diffusion tensor imaging


Summary: The use of diffusion ANISOTROPY data from diffusion magnetic resonance imaging results to construct images based on the direction of the faster diffusing molecules.

Top Publications

  1. Aguirre G, Butt O, Datta R, Roman A, Sumaroka A, Schwartz S, et al. Postretinal Structure and Function in Severe Congenital Photoreceptor Blindness Caused by Mutations in the GUCY2D Gene. Invest Ophthalmol Vis Sci. 2017;58:959-973 pubmed publisher
    ..of the size of the optic chiasm, and the fractional anisotropy of the optic radiations as measured with diffusion tensor imaging was also normal. These results identify dissociable effects of blindness upon the visual pathway...
  2. Pasi M, van Uden I, Tuladhar A, de Leeuw F, Pantoni L. White Matter Microstructural Damage on Diffusion Tensor Imaging in Cerebral Small Vessel Disease: Clinical Consequences. Stroke. 2016;47:1679-84 pubmed publisher
  3. Rangaprakash D, Deshpande G, Daniel T, Goodman A, Robinson J, Salibi N, et al. Compromised hippocampus-striatum pathway as a potential imaging biomarker of mild-traumatic brain injury and posttraumatic stress disorder. Hum Brain Mapp. 2017;38:2843-2864 pubmed publisher
    ..Hum Brain Mapp 38:2843-2864, 2017. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc. ..
  4. Chang Y, Kemmotsu N, Leyden K, Kucukboyaci N, Iragui V, Tecoma E, et al. Multimodal imaging of language reorganization in patients with left temporal lobe epilepsy. Brain Lang. 2017;170:82-92 pubmed publisher
    ..Fourteen patients with LTLE and 26 controls underwent structural MRI, functional MRI, diffusion tensor imaging, and neuropsychological language tasks...
  5. Lagana M, Rovaris M, Ceccarelli A, Venturelli C, Marini S, Baselli G. DTI parameter optimisation for acquisition at 1.5T: SNR analysis and clinical application. Comput Intell Neurosci. 2010;:254032 pubmed publisher
    Magnetic Resonance (MR) diffusion tensor imaging (DTI) is able to quantify in vivo tissue microstructure properties and to detect disease related pathology of the central nervous system...
  6. Benjamin P, Zeestraten E, Lambert C, Ster I, Williams O, Lawrence A, et al. Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials. J Cereb Blood Flow Metab. 2016;36:228-40 pubmed
    ..change in brain volume, T2 white matter hyperintensity (WMH) volume, lacunes, and white matter damage on diffusion tensor imaging (DTI). Over 3 years, change was detectable in all MRI markers but not in cognitive measures...
  7. Daducci A, Dal Palù A, Lemkaddem A, Thiran J. COMMIT: Convex optimization modeling for microstructure informed tractography. IEEE Trans Med Imaging. 2015;34:246-57 pubmed publisher
    ..Results clearly demonstrate the benefits of the proposed formulation, opening new perspectives for a more quantitative and biologically plausible assessment of the structural connectivity of the brain. ..
  8. Grieve S, Korgaonkar M, Etkin A, Harris A, Koslow S, Wisniewski S, et al. Brain imaging predictors and the international study to predict optimized treatment for depression: study protocol for a randomized controlled trial. Trials. 2013;14:224 pubmed publisher
    ..International Study to Predict Optimized Treatment--in Depression (iSPOT-D). ClinicalTrials.gov, NCT00693849. ..
  9. Mayer E, Tillisch K, Ellingson B. Dyspepsia: Structural changes in functional gastrointestinal disorders. Nat Rev Gastroenterol Hepatol. 2013;10:200-2 pubmed publisher

More Information


  1. Lee R, Foster K, Lillard J, Klimo P, Ellison D, Orr B, et al. Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors. J Neurosurg Pediatr. 2017;20:247-255 pubmed publisher
    ..RESULTS On preoperative diffusion tensor imaging tractography (performed in 12 patients), the ipsilateral corticospinal tract was displaced laterally in 1 ..
  2. van Dijken B, Yan J, Boonzaier N, Li C, van Laar P, van der Hoorn A, et al. Subventricular Zone Involvement Characterized by Diffusion Tensor Imaging in Glioblastoma. World Neurosurg. 2017;105:697-701 pubmed publisher
    ..zone is the main source of neural stem cells, we aimed at characterizing the subventricular zone using diffusion tensor imaging (DTI) to show subventricular zone involvement in glioblastoma...
  3. Caspell Garcia C, Simuni T, Tosun Turgut D, Wu I, Zhang Y, Nalls M, et al. Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease. PLoS ONE. 2017;12:e0175674 pubmed publisher
    ..computed tomography (SPECT) scan, structural magnetic resonance imaging (MRI; volume and thickness), diffusion tensor imaging (mean diffusivity and fractional anisotropy), cerebrospinal fluid (CSF; amyloid beta [A?], tau and alpha ..
  4. Maillard P, Mitchell G, Himali J, Beiser A, Fletcher E, Tsao C, et al. Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury. Stroke. 2017;48:1567-1573 pubmed publisher
  5. Bonilha L, Hillis A, Hickok G, den Ouden D, Rorden C, Fridriksson J. Temporal lobe networks supporting the comprehension of spoken words. Brain. 2017;140:2370-2380 pubmed publisher
    ..Magnetic resonance imaging (T1-weighted and diffusion tensor imaging-based structural connectome), auditory word comprehension and object recognition tests were obtained from ..
  6. Wang X, Casadio M, Weber K, Mussa Ivaldi F, Parrish T. White matter microstructure changes induced by motor skill learning utilizing a body machine interface. Neuroimage. 2014;88:32-40 pubmed publisher
    ..These changes may underlie the functional reorganization associated with motor skill learning. ..
  7. Spiegelhalder K, Regen W, Prem M, Baglioni C, Nissen C, Feige B, et al. Reduced anterior internal capsule white matter integrity in primary insomnia. Hum Brain Mapp. 2014;35:3431-8 pubmed
    ..In this study, diffusion tensor imaging (DTI) was used in a well-characterized sample of primary insomnia (PI) patients and good sleeper controls ..
  8. Martino D, Delorme C, Pelosin E, Hartmann A, Worbe Y, Avanzino L. Abnormal lateralization of fine motor actions in Tourette syndrome persists into adulthood. PLoS ONE. 2017;12:e0180812 pubmed publisher
    ..index [(single RH-bimanual RH)/single RH X 100) for percentage of correct movements (%CORR); 2) MRI-based diffusion tensor imaging and probabilistic tractography of inter-hemispheric corpus callosum (CC) connections between ..
  9. Underwood E. Neuroscience. NFL kicks off brain injury research effort. Science. 2013;339:1367 pubmed publisher
  10. Schulz R, Park E, Lee J, Chang W, Lee A, Kim Y, et al. Interactions Between the Corticospinal Tract and Premotor-Motor Pathways for Residual Motor Output After Stroke. Stroke. 2017;48:2805-2811 pubmed publisher
    ..This finding might have important implications for future research on recovery prediction models and on responses to treatment strategies. ..
  11. Jang S, Kwon H. Aggravation of an injured dentato-rubro-thalamic tract in a patient with mild traumatic brain injury: A case report. Medicine (Baltimore). 2017;96:e8253 pubmed publisher
    ..We report on a patient with mild traumatic brain injury (TBI) by follow-up diffusion tensor tractography (DTT), and observed for approximately nine monthsby serial diffusion tensor tractography (DTT)...
  12. Elnakib A, Soliman A, Nitzken M, Casanova M, Gimel farb G, El Baz A. Magnetic resonance imaging findings for dyslexia: a review. J Biomed Nanotechnol. 2014;10:2778-805 pubmed
    ..We focus on three MRI techniques: structural MRI, functional MRI, and diffusion tensor imaging. Structural MRI reveals dyslexia-associated volumetric and shape-based abnormalities in different brain ..
  13. Cavallari M, Dai W, Guttmann C, Meier D, Ngo L, Hshieh T, et al. Longitudinal diffusion changes following postoperative delirium in older people without dementia. Neurology. 2017;89:1020-1027 pubmed publisher
    To investigate the effect of postoperative delirium on longitudinal brain microstructural changes, as measured by diffusion tensor imaging.
  14. Killiany R. Are white matter signal abnormalities clinically relevant?. Neurology. 2010;74:1014-5 pubmed publisher
  15. Hiremath S, Muraleedharan A, Kumar S, Nagesh C, Kesavadas C, Abraham M, et al. Combining Diffusion Tensor Metrics and DSC Perfusion Imaging: Can It Improve the Diagnostic Accuracy in Differentiating Tumefactive Demyelination from High-Grade Glioma?. AJNR Am J Neuroradiol. 2017;38:685-690 pubmed publisher
    ..DTI and DSC perfusion add profoundly to conventional imaging in differentiating tumefactive demyelinating lesions and high-grade gliomas. The combination of DTI metrics and DSC perfusion markedly improved diagnostic accuracy. ..
  16. Monnot C, Zhang X, Nikkhou Aski S, Damberg P, Svenningsson P. Asymmetric dopaminergic degeneration and levodopa alter functional corticostriatal connectivity bilaterally in experimental parkinsonism. Exp Neurol. 2017;292:11-20 pubmed publisher
    ..In accordance with a neurodegeneration of the nigrostriatal dopaminergic pathway, diffusion tensor imaging showed increased radial diffusivity and decreased fractional anisotropy in the lesioned substantia nigra...
  17. Acheson A, Wijtenburg S, Rowland L, Winkler A, Mathias C, Hong L, et al. Reproducibility of tract-based white matter microstructural measures using the ENIGMA-DTI protocol. Brain Behav. 2017;7:e00615 pubmed publisher
    ..FA) values, measured using the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA)-diffusion tensor imaging (DTI) protocol...
  18. Moroso A, Ruet A, Lamargue Hamel D, Munsch F, Deloire M, Coupe P, et al. Microstructural analyses of the posterior cerebellar lobules in relapsing-onset multiple sclerosis and their implication in cognitive impairment. PLoS ONE. 2017;12:e0182479 pubmed publisher
    ..36 matched healthy subjects (HS) underwent 3T magnetic resonance imaging, including 3D T1-weighted and diffusion tensor imaging (DTI)...
  19. Kochunov P, Coyle T, Rowland L, Jahanshad N, Thompson P, Kelly S, et al. Association of White Matter With Core Cognitive Deficits in Patients With Schizophrenia. JAMA Psychiatry. 2017;74:958-966 pubmed publisher
    ..Efforts to remediate the multiple cognitive function impairments in schizophrenia should consider white matter as one of the underlying neural mechanisms...
  20. van Duinkerken E, Schoonheim M, Ijzerman R, Klein M, Ryan C, Moll A, et al. Diffusion tensor imaging in type 1 diabetes: decreased white matter integrity relates to cognitive functions. Diabetologia. 2012;55:1218-20 pubmed publisher
  21. Castronovo V, Scifo P, Castellano A, Aloia M, Iadanza A, Marelli S, et al. White matter integrity in obstructive sleep apnea before and after treatment. Sleep. 2014;37:1465-75 pubmed publisher
    ..CPAP. WM integrity measured by diffusion tensor imaging (DTI) and cognitive performance (measured with neuropsychological testing) before and after 3 and 12 ..
  22. Jang S, Kwon H. Injury of the dentato-rubro-thalamic tract in patients with cerebellar infarct: Case report. Medicine (Baltimore). 2017;96:e7220 pubmed publisher
    ..Three patients with cerebellar infarct were enrolled in this study. Diffusion tensor imaging data were acquired at 3 weeks (patient 1) and 2 weeks (patients 2 and 3) after onset and the DRTT was ..
  23. Jang S, Lee H. Delayed recovery of the affected finger extensors at chronic stage in a stroke patient: A case report. Medicine (Baltimore). 2017;96:e8023 pubmed publisher
    ..A 33-year-old male presented with complete weakness of the right extremities due to corona radiata infarct...
  24. Raco A, Pesce A, Fraschetti F, Frati A, D Andrea G, Cimatti M, et al. Motor Outcomes After Surgical Resection of Lesions Involving the Motor Pathway: A Prognostic Evaluation Scale. World Neurosurg. 2017;103:748-756 pubmed publisher
    ..682 times greater for the higher ES classes (IV-VI). The anatomic features of lesions are crucial in the prediction of motor outcome. The new proposed score (ES score) is useful to stratify motor function prognosis. ..
  25. Wang E, Wu Y, Cheung J, Zhou I, Igarashi T, Zhang X, et al. pH imaging reveals worsened tissue acidification in diffusion kurtosis lesion than the kurtosis/diffusion lesion mismatch in an animal model of acute stroke. J Cereb Blood Flow Metab. 2017;37:3325-3333 pubmed publisher
    ..Our work documented initial evidence that DKI may reveal the heterogeneous metabolic derangement within the commonly used DWI lesion. ..
  26. Postal M, Lapa A, Reis F, Rittner L, Appenzeller S. Magnetic resonance imaging in neuropsychiatric systemic lupus erythematosus: current state of the art and novel approaches. Lupus. 2017;26:517-521 pubmed publisher
    ..This review will highlight different magnetic resonance imaging techniques, including the advanced magnetic resonance imaging methods used to determine central nervous system involvement in systemic lupus erythematosus. ..
  27. Reislev N, Dyrby T, Siebner H, Lundell H, Ptito M, Kupers R. Thalamocortical Connectivity and Microstructural Changes in Congenital and Late Blindness. Neural Plast. 2017;2017:9807512 pubmed publisher
    ..network between congenitally blind individuals, late blind individuals, and normal sighted controls, diffusion tensor imaging (DTI) indices revealed significant microstructural changes within thalamic clusters of both blind groups...
  28. Gao B, Shen X, Shiroishi M, Pang M, Li Z, Yu B, et al. A pilot study of pre-operative motor dysfunction from gliomas in the region of corticospinal tract: Evaluation with diffusion tensor imaging. PLoS ONE. 2017;12:e0182795 pubmed publisher
    ..aim of this study is to evaluate the effect of gliomas located in the CST region on motor function with diffusion tensor imaging (DTI) preoperatively...
  29. Mah A, Geeraert B, Lebel C. Detailing neuroanatomical development in late childhood and early adolescence using NODDI. PLoS ONE. 2017;12:e0182340 pubmed publisher
    b>Diffusion tensor imaging (DTI) studies have provided much evidence of white and subcortical gray matter changes during late childhood and early adolescence that suggest increasing myelination, axon density, and/or fiber coherence...
  30. Owens J, Spitz G, Ponsford J, Dymowski A, Ferris N, Willmott C. White matter integrity of the medial forebrain bundle and attention and working memory deficits following traumatic brain injury. Brain Behav. 2017;7:e00608 pubmed publisher
    ..This study investigated white matter microstructure of the medial MFB, specifically the supero-lateral branch (slMFB), following TBI, and its association with performance on attention and working memory tasks...
  31. Raval S, Britton C, Zhao T, Krishnamurthy N, Santini T, Gorantla V, et al. Ultra-high field upper extremity peripheral nerve and non-contrast enhanced vascular imaging. PLoS ONE. 2017;12:e0175629 pubmed publisher
    ..T2] double-echo steady state [DESS], susceptibility weighted imaging [SWI], time-of-flight [TOF], diffusion tensor imaging [DTI], and diffusion spectrum imaging [DSI] were optimized and incorporated with a radiofrequency [RF] ..
  32. Wardlaw J, Chappell F, Valdés Hernández M, Makin S, Staals J, Shuler K, et al. White matter hyperintensity reduction and outcomes after minor stroke. Neurology. 2017;89:1003-1010 pubmed publisher
    ..The role of risk factor control requires verification. Interstitial fluid alterations may account for some WMH reversibility, offering potential intervention targets. ..
  33. Croall I, Lohner V, Moynihan B, Khan U, Hassan A, O Brien J, et al. Using DTI to assess white matter microstructure in cerebral small vessel disease (SVD) in multicentre studies. Clin Sci (Lond). 2017;131:1361-1373 pubmed publisher
    b>Diffusion tensor imaging (DTI) metrics such as fractional anisotropy (FA) and mean diffusivity (MD) have been proposed as clinical trial markers of cerebral small vessel disease (SVD) due to their associations with outcomes such as ..
  34. Wang S, Yuan J, Guo X, Teng L, Jiang H, Gu H, et al. Correlation between prefrontal-striatal pathway impairment and cognitive impairment in patients with leukoaraiosis. Medicine (Baltimore). 2017;96:e6703 pubmed publisher
    ..aimed to investigate the changes of white matter microstructure of cortico-subcortical pathways using diffusion tensor imaging (DTI), and to explore the relationship between abnormal parameters of DTI and cognitive function ..
  35. Koerte I, Ertl Wagner B, Reiser M, Zafonte R, Shenton M. White matter integrity in the brains of professional soccer players without a symptomatic concussion. JAMA. 2012;308:1859-61 pubmed publisher
  36. Ruff C, Faulkner S, Rumajogee P, Beldick S, Foltz W, Corrigan J, et al. The extent of intrauterine growth restriction determines the severity of cerebral injury and neurobehavioural deficits in rodents. PLoS ONE. 2017;12:e0184653 pubmed publisher
    ..This model has the potential to be applied to examine the pathobiology of and potential therapeutic strategies for IUGR-related brain injury. Thus, this work has potential translational relevance for the study of CP. ..
  37. Vaeggemose M, Pham M, Ringgaard S, Tankisi H, Ejskjaer N, Heiland S, et al. Magnetic Resonance Neurography Visualizes Abnormalities in Sciatic and Tibial Nerves in Patients With Type 1 Diabetes and Neuropathy. Diabetes. 2017;66:1779-1788 pubmed publisher
    This study evaluates whether diffusion tensor imaging magnetic resonance neurography (DTI-MRN), T2 relaxation time, and proton spin density can detect and grade neuropathic abnormalities in patients with type 1 diabetes...
  38. Sârbu N, Toledano P, Calvo A, Roura E, Sarbu M, Espinosa G, et al. Advanced MRI techniques: biomarkers in neuropsychiatric lupus. Lupus. 2017;26:510-516 pubmed publisher
    ..Conclusions Atrophy and microstructural damage in fronto-temporal WM and GM in NPSLE correlate with severity, activity and the time from disease onset. Antimalarial treatment seems to give some brain-protective effects. ..
  39. Simon N, Narvid J, Cage T, Banerjee S, Ralph J, Engstrom J, et al. Visualizing axon regeneration after peripheral nerve injury with magnetic resonance tractography. Neurology. 2014;83:1382-4 pubmed publisher
  40. Wong Y, Tan L, Seow P, Tan M, Abd Kadir K, Vijayananthan A, et al. Microstructural integrity of white matter tracts amongst older fallers: A DTI study. PLoS ONE. 2017;12:e0179895 pubmed publisher
    ..85 participants (43 fallers, 42 non-fallers) were evaluated with conventional MRI and diffusion tensor imaging (DTI) sequences of the brain...
  41. Fragata I, Alves M, Papoila A, Nunes A, Ferreira P, Canto Moreira N, et al. Early Prediction of Delayed Ischemia and Functional Outcome in Acute Subarachnoid Hemorrhage: Role of Diffusion Tensor Imaging. Stroke. 2017;48:2091-2097 pubmed publisher
    b>Diffusion tensor imaging (DTI) parameters are markers of cerebral lesion in some diseases...
  42. Chaves M, Bettini M, Fernandez M, Basalo M, Rojas J, Besada C, et al. Usefulness of diffusion tensor imaging in amyotrophic lateral sclerosis: potential biomarker and association with the cognitive profile. Arq Neuropsiquiatr. 2017;75:272-276 pubmed publisher
    ..The DTI showed white matter damage in ALS patients vs. healthy controls (p < 0.001). In our preliminary study the alterations of white matter in DTI were significantly associated with cognitive impairment in patients with ALS. ..
  43. Widerstrom Noga E. Neuropathic Pain and Spinal Cord Injury: Phenotypes and Pharmacological Management. Drugs. 2017;77:967-984 pubmed publisher
  44. Coenen V, Várkuti B, Parpaley Y, Skodda S, Prokop T, Urbach H, et al. Postoperative neuroimaging analysis of DRT deep brain stimulation revision surgery for complicated essential tremor. Acta Neurochir (Wien). 2017;159:779-787 pubmed publisher
    ..Direct targeting with DTI FT-assisted approaches in a variety of indications is the focus of our ongoing research. ..
  45. Aoki Y, Yoncheva Y, Chen B, Nath T, Sharp D, Lazar M, et al. Association of White Matter Structure With Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder. JAMA Psychiatry. 2017;74:1120-1128 pubmed publisher
    ..Clinical overlap between autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) is increasingly appreciated, but the underlying brain mechanisms remain unknown to date...
  46. Jiang Y, Mao L, Yan X, Fan M, Wang X, Ding J, et al. Investigation of altered microstructure in patients with drug refractory epilepsy using diffusion tensor imaging. Neuroradiology. 2017;59:597-608 pubmed publisher
    ..analysis (VWA) and tract-based spatial statistics (TBSS) methods to measure microstructural changes using diffusion tensor imaging (DTI) in patients of drug refractory epilepsy (DRE) who had been epileptic for more than 10 years...
  47. Seo J, Chang M. Degeneration of corticofugal fibers in a patient with primary progressive freezing gait: A case report. Medicine (Baltimore). 2017;96:e6840 pubmed publisher
    ..From the patient and 20 age- and sex- matched normal controls, diffusion tensor imaging data were acquired using a 1.5 T magnetic resonance scanner...
  48. Lindemer E, Greve D, Fischl B, Augustinack J, Salat D. Regional staging of white matter signal abnormalities in aging and Alzheimer's disease. Neuroimage Clin. 2017;14:156-165 pubmed publisher
    ..White matter staging could play an important role in a better understanding and the treatment of cerebrovascular contributions to brain aging and dementia. ..
  49. Shankar B, Narayanan R, Muralitharan P, Ulaganathan B. Evaluation of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) by diffusion-weighted and diffusion tensor imaging. BMJ Case Rep. 2014;2014: pubmed publisher
    ..We present a case of MERS evaluated with diffusion-weighted and diffusion tensor imaging along with various conventional sequences of MRI...
  50. Lucas Jiménez O, Díez Cirarda M, Ojedaa N, Pena J, Cabrera Zubizarreta A, Ibarretxe Bilbao N. Verbal Memory in Parkinson's Disease: A Combined DTI and fMRI Study. J Parkinsons Dis. 2015;5:793-804 pubmed
    ..Functional magnetic resonance imaging (fMRI) while performing a verbal memory paradigm and diffusion tensor imaging data (DTI), were acquired in 37 PD patients and 15 age-, sex-, and education-matched HC...
  51. Svärd D, Nilsson M, Lampinen B, Lätt J, Sundgren P, Stomrud E, et al. The effect of white matter hyperintensities on statistical analysis of diffusion tensor imaging in cognitively healthy elderly and prodromal Alzheimer's disease. PLoS ONE. 2017;12:e0185239 pubmed publisher
    b>Diffusion tensor imaging (DTI) has been used to study microstructural white matter alterations in a variety of conditions including normal aging and Alzheimer's disease (AD)...
  52. Hammond D, Scherrer B, Warfield S. Cortical graph smoothing: a novel method for exploiting DWI-derived anatomical brain connectivity to improve EEG source estimation. IEEE Trans Med Imaging. 2013;32:1952-63 pubmed publisher
    ..Evaluated over a series of 18 subjects, the proposed cortical graph smoothing method shows superior localization accuracy compared to the minimum norm method, and greater relative peak intensity than the other comparison methods. ..
  53. Javadi S, Nabavi A, Giordano M, Faghihzadeh E, Samii A. Evaluation of Diffusion Tensor Imaging-Based Tractography of the Corticospinal Tract: A Correlative Study With Intraoperative Magnetic Resonance Imaging and Direct Electrical Subcortical Stimulation. Neurosurgery. 2017;80:287-299 pubmed publisher
    The accuracy of intraoperative diffusion tensor imaging (DTI)–based tractography of the corticospinal tract (CST) is crucial for its use in neurosurgical planning and its implementation in image-guided surgery...
  54. Lam B, Halliday G, Irish M, Hodges J, Piguet O. Longitudinal white matter changes in frontotemporal dementia subtypes. Hum Brain Mapp. 2014;35:3547-57 pubmed
    ..Our results indicate that investigations of white matter changes reveal important differences across FTD syndromes with disease progression. ..
  55. Tournier J, Mori S, Leemans A. Diffusion tensor imaging and beyond. Magn Reson Med. 2011;65:1532-56 pubmed publisher
  56. Liu G, Tan S, Dang C, Peng K, Xie C, Xing S, et al. Motor Recovery Prediction With Clinical Assessment and Local Diffusion Homogeneity After Acute Subcortical Infarction. Stroke. 2017;48:2121-2128 pubmed publisher
    Initial clinical assessment or conventional diffusion tensor imaging parameters alone do not reliably predict poststroke recovery of motor function...
  57. Zhou Y, Liu J, Driesen N, Womer F, Chen K, Wang Y, et al. White Matter Integrity in Genetic High-Risk Individuals and First-Episode Schizophrenia Patients: Similarities and Disassociations. Biomed Res Int. 2017;2017:3107845 pubmed publisher
    ..and differences in WM connectivity between those at-risk for and in early stages of SZ, a cross-sectional diffusion tensor imaging study of 48 individuals diagnosed with first-episode SZ (FE-SZ), 37 nonpsychotic individuals at a high ..
  58. Wang M, Owen J, Mukherjee P, Raj A. Brain network eigenmodes provide a robust and compact representation of the structural connectome in health and disease. PLoS Comput Biol. 2017;13:e1005550 pubmed publisher
  59. Apostolidis L, Schwarz D, Xia A, Weiler M, Heckel A, Godel T, et al. Dorsal root ganglia hypertrophy as in vivo correlate of oxaliplatin-induced polyneuropathy. PLoS ONE. 2017;12:e0183845 pubmed publisher
    ..plexus and both sciatic nerves and their branches using T2-weighted fat-saturated sequences and diffusion tensor imaging. Quantitative assessment included volumetry of the dorsal root ganglia (DRG), sciatic nerve normalized T2 ..
  60. Hobert M, Stein V, Dziallas P, Ludwig D, Tipold A. Evaluation of normal appearing spinal cord by diffusion tensor imaging, fiber tracking, fractional anisotropy, and apparent diffusion coefficient measurement in 13 dogs. Acta Vet Scand. 2013;55:36 pubmed publisher
    ..b>Diffusion tensor imaging (DTI) is a technique sensitive to the random motion of water providing information about tissue ..
  61. Filippi M, Agosta F, Grosskreutz J, Benatar M, Kassubek J, Verstraete E, et al. Progress towards a neuroimaging biomarker for amyotrophic lateral sclerosis. Lancet Neurol. 2015;14:786-788 pubmed publisher
  62. Keong N, Pena A, Price S, Czosnyka M, Czosnyka Z, DeVito E, et al. Diffusion tensor imaging profiles reveal specific neural tract distortion in normal pressure hydrocephalus. PLoS ONE. 2017;12:e0181624 pubmed publisher
    ..We used diffusion tensor imaging (DTI) to explore the topography and reversibility of white matter injury in NPH pre- and early after ..
  63. Chen M, Chen P, Lu C, Chen H, Chao Y, Li S, et al. Plasma DNA Mediate Autonomic Dysfunctions and White Matter Injuries in Patients with Parkinson's Disease. Oxid Med Cell Longev. 2017;2017:7371403 pubmed publisher
    ..This model could provide us with a piece of the puzzle of the entire PD pathogenesis. ..
  64. Borsodi F, Culea V, Langkammer C, Khalil M, Pirpamer L, Quasthoff S, et al. Multimodal assessment of white matter tracts in amyotrophic lateral sclerosis. PLoS ONE. 2017;12:e0178371 pubmed publisher
    ..proposed to investigate microstructural tissue changes in amyotrophic lateral sclerosis (ALS) including diffusion tensor imaging (DTI), magnetization transfer imaging, and R2* mapping...
  65. Maggipinto T, Bellotti R, Amoroso N, Diacono D, Donvito G, Lella E, et al. DTI measurements for Alzheimer's classification. Phys Med Biol. 2017;62:2361-2375 pubmed publisher
    b>Diffusion tensor imaging (DTI) is a promising imaging technique that provides insight into white matter microstructure integrity and it has greatly helped identifying white matter regions affected by Alzheimer's disease (AD) in its early ..
  66. Reijmer Y, van Veluw S, Greenberg S. Ischemic brain injury in cerebral amyloid angiopathy. J Cereb Blood Flow Metab. 2016;36:40-54 pubmed
    ..white-matter hyperintensities, microinfarcts, and microstructural tissue abnormalities as detected with diffusion tensor imaging. Furthermore, imaging markers of ischemic disease show a robust association with cognition, independent ..
  67. Hänggi J, Vitacco D, Hilti L, Luechinger R, Kraemer B, Brugger P. Structural and functional hyperconnectivity within the sensorimotor system in xenomelia. Brain Behav. 2017;7:e00657 pubmed publisher
    ..We compared structural and functional connectivity between 13 xenomelic men with matched controls using diffusion tensor imaging combined with fiber tractography and resting state functional magnetic resonance imaging...
  68. Thiel A, Vahdat S. Structural and resting-state brain connectivity of motor networks after stroke. Stroke. 2015;46:296-301 pubmed publisher
  69. Medaglia J, Huang W, Segarra S, Olm C, Gee J, Grossman M, et al. Brain network efficiency is influenced by the pathologic source of corticobasal syndrome. Neurology. 2017;89:1373-1381 pubmed publisher
    ..regions by the number of white matter streamlines identified in a deterministic tractography analysis of diffusion tensor imaging data...
  70. Lord L, Stevner A, Deco G, Kringelbach M. Understanding principles of integration and segregation using whole-brain computational connectomics: implications for neuropsychiatric disorders. Philos Trans A Math Phys Eng Sci. 2017;375: pubmed publisher
    ..This article is part of the themed issue 'Mathematical methods in medicine: neuroscience, cardiology and pathology'. ..
  71. Duffau H. The dangers of magnetic resonance imaging diffusion tensor tractography in brain surgery. World Neurosurg. 2014;81:56-8 pubmed publisher
  72. Jang S, Seo J. Injury of optic radiation and visual field defect in a patient with aneurysmal subarachnoid hemorrhage: A case report. Medicine (Baltimore). 2017;96:e7356 pubmed publisher
    ..On the configuration of the OR of the patient, both ORs were thinner than those of normal control subjects. Injury of the OR was demonstrated in a patient with a visual field defect following aneurysmal SAH, using DTT. ..
  73. Takemura H, Pestilli F, Weiner K, Keliris G, Landi S, Sliwa J, et al. Occipital White Matter Tracts in Human and Macaque. Cereb Cortex. 2017;27:3346-3359 pubmed publisher
    ..These similarities and differences between the occipital lobe tracts will be useful in establishing which circuitry in the macaque can serve as an accurate model for human visual cortex...
  74. Cheng C, Hsu C, Huang Y, Tsai Y, Hsu H, Yang W, et al. Motor outcome of deep intracerebral haemorrhage in diffusion tensor imaging: comparison of data from different locations along the corticospinal tract. Neurol Res. 2015;37:774-81 pubmed publisher
    Although diffusion tensor imaging (DTI) is widely studied to assess the motor outcome after ischaemic stroke, there is paucity of data regarding outcomes of intracerebral haemorrhage (ICH)...
  75. Buch E, Rizk S, Nicolo P, Cohen L, Schnider A, Guggisberg A. Predicting motor improvement after stroke with clinical assessment and diffusion tensor imaging. Neurology. 2016;86:1924-5 pubmed publisher
  76. Olivito G, Dayan M, Battistoni V, Clausi S, Cercignani M, Molinari M, et al. Bilateral effects of unilateral cerebellar lesions as detected by voxel based morphometry and diffusion imaging. PLoS ONE. 2017;12:e0180439 pubmed publisher
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    Perinatal stroke injures developing motor systems, resulting in hemiparetic cerebral palsy. Diffusion tensor imaging can explore structural connectivity...
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