Summary: Recording of brain electrical activities in which the electrodes are placed directly on the CEREBRAL CORTEX.

Top Publications

  1. Fedele T, Schönenberger C, Curio G, Serra C, Krayenbühl N, Sarnthein J. Intraoperative subdural low-noise EEG recording of the high frequency oscillation in the somatosensory evoked potential. Clin Neurophysiol. 2017;128:1851-1857 pubmed publisher
    ..Low-noise EEG might critically improve the detectability of interictal spontaneous HFO in subdural and possibly in scalp recordings. ..
  2. Jiang H, Schuele S, Rosenow J, Zelano C, Parvizi J, Tao J, et al. Theta Oscillations Rapidly Convey Odor-Specific Content in Human Piriform Cortex. Neuron. 2017;94:207-219.e4 pubmed publisher
    ..Together these findings suggest that human piriform cortex has access to olfactory content in the time-frequency domain and can utilize these signals to rapidly differentiate odor stimuli. ..
  3. Zhang R, Ren Y, Liu C, Xu N, Li X, Cong F, et al. Temporal-spatial characteristics of phase-amplitude coupling in electrocorticogram for human temporal lobe epilepsy. Clin Neurophysiol. 2017;128:1707-1718 pubmed publisher
    ..Phase-amplitude coupling can provide meaningful reference for accurate resection of epileptogenic focus and provide insight into the underlying neural dynamics of the epileptic seizure in patients with temporal lobe epilepsy. ..
  4. Fedele T, Ramantani G, Burnos S, Hilfiker P, Curio G, Grunwald T, et al. Prediction of seizure outcome improved by fast ripples detected in low-noise intraoperative corticogram. Clin Neurophysiol. 2017;128:1220-1226 pubmed publisher
    ..Prediction of seizure outcome was improved by the optimal integration of low-noise EEG and unsupervised FR detection. Accurate, automated and fast FR rating is essential for consideration of FR in the intraoperative setting. ..
  5. Nishida M, Korzeniewska A, Crone N, Toyoda G, Nakai Y, Ofen N, et al. Brain network dynamics in the human articulatory loop. Clin Neurophysiol. 2017;128:1473-1487 pubmed publisher
    ..The articulatory loop employs sustained reciprocal propagation of neural activity across a network of cortical sites with strong neurophysiological connectivity. ..
  6. Aarabi A, He B. Seizure prediction in patients with focal hippocampal epilepsy. Clin Neurophysiol. 2017;128:1299-1307 pubmed publisher
    ..The spatio-temporal characterization of preictal periods may help to better understand the mechanism underlying seizure generation in patients with focal hippocampal epilepsy. ..
  7. Zhang G, Chen G, Meng D, Liu Y, Chen J, Shu L, et al. Stereoelectroencephalography based on the Leksell stereotactic frame and Neurotech operation planning software. Medicine (Baltimore). 2017;96:e7106 pubmed publisher
    ..The L-SEEG system with Neurotech operation planning software can be used for safe, accurate, and reliable intracranial electrode implantation for SEEG. ..
  8. Gradwohl G, Olini N, Huber R. Sleep/wake movement velocities, trajectories and micro-arousals during maturation in rats. BMC Neurosci. 2017;18:24 pubmed publisher
    ..These dynamic measures may represent new indicators for changes in sleep regulatory processes across maturation. ..
  9. Lopes M, Richardson M, Abela E, Rummel C, Schindler K, Goodfellow M, et al. An optimal strategy for epilepsy surgery: Disruption of the rich-club?. PLoS Comput Biol. 2017;13:e1005637 pubmed publisher
    ..We show that the postsurgical outcome for these patients was better when a greater proportion of the rich club was removed, in agreement with our theoretical predictions. ..

More Information


  1. Berezutskaya J, Freudenburg Z, Güçlü U, van Gerven M, Ramsey N. Neural Tuning to Low-Level Features of Speech throughout the Perisylvian Cortex. J Neurosci. 2017;37:7906-7920 pubmed publisher
    ..Two complementary imaging techniques were used with human participants (both males and females): electrocorticography (ECoG) and fMRI...
  2. Murugesan S, Bouchard K, Chang E, Dougherty M, Hamann B, Weber G. Multi-scale visual analysis of time-varying electrocorticography data via clustering of brain regions. BMC Bioinformatics. 2017;18:236 pubmed publisher
    There exists a need for effective and easy-to-use software tools supporting the analysis of complex Electrocorticography (ECoG) data...
  3. Baldassano S, Brinkmann B, UNG H, Blevins T, Conrad E, Leyde K, et al. Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings. Brain. 2017;140:1680-1691 pubmed publisher
    ..The success of this competition demonstrates how sharing code and high quality data results in the creation of powerful translational tools with significant potential to impact patient care. ..
  4. Bar Klein G, Lublinsky S, Kamintsky L, Noyman I, Veksler R, Dalipaj H, et al. Imaging blood-brain barrier dysfunction as a biomarker for epileptogenesis. Brain. 2017;140:1692-1705 pubmed publisher
    ..imaging to quantitatively follow blood-brain barrier pathology in rats following status epilepticus, late electrocorticography to identify epileptic animals and post-mortem immunohistochemistry to confirm blood-brain barrier ..
  5. van t Klooster M, van Klink N, Zweiphenning W, Leijten F, Zelmann R, Ferrier C, et al. Tailoring epilepsy surgery with fast ripples in the intraoperative electrocorticogram. Ann Neurol. 2017;81:664-676 pubmed publisher
    Intraoperative electrocorticography (ECoG) can be used to delineate the resection area in epilepsy surgery. High-frequency oscillations (HFOs; 80-500 Hz) seem better biomarkers for epileptogenic tissue than spikes...
  6. Bourdillon P, Ryvlin P, Isnard J, Montavont A, Catenoix H, Mauguiere F, et al. Stereotactic Electroencephalography Is a Safe Procedure, Including for Insular Implantations. World Neurosurg. 2017;99:353-361 pubmed publisher
    ..52%), acute pneumocephalus (0.38%), and local cutaneous infection (0.19%). SEEG is a safe procedure. Insular trajectories cannot be considered an additional risk of intracranial bleeding. ..
  7. Bartolomei F, Lagarde S, Wendling F, McGonigal A, Jirsa V, Guye M, et al. Defining epileptogenic networks: Contribution of SEEG and signal analysis. Epilepsia. 2017;58:1131-1147 pubmed publisher
    ..The epileptogenic network concept is a key factor in identifying the anatomic distribution of the epileptogenic process, which is particularly important in the context of epilepsy surgery. ..
  8. Hermes D, Nguyen M, Winawer J. Neuronal synchrony and the relation between the blood-oxygen-level dependent response and the local field potential. PLoS Biol. 2017;15:e2001461 pubmed publisher
  9. Zea Vera A, Aungaroon G, Horn P, Byars A, Greiner H, Tenney J, et al. Language and motor function thresholds during pediatric extra-operative electrical cortical stimulation brain mapping. Clin Neurophysiol. 2017;128:2087-2093 pubmed publisher
    ..Functional and AD/seizure thresholds relationships suggest individual differences in cortical excitability which cannot be explained by clinical variables. ..
  10. Aungaroon G, Zea Vera A, Horn P, Byars A, Greiner H, Tenney J, et al. After-discharges and seizures during pediatric extra-operative electrical cortical stimulation functional brain mapping: Incidence, thresholds, and determinants. Clin Neurophysiol. 2017;128:2078-2086 pubmed publisher
    ..ADs and seizures during ECS brain mapping are potentially hazardous and affect its functional validity. Thus, safer method(s) for brain mapping with improved neurophysiologic validity are desirable. ..
  11. Suzuki M, Larkum M. Dendritic calcium spikes are clearly detectable at the cortical surface. Nat Commun. 2017;8:276 pubmed publisher
  12. Talakoub O, Marquez Chin C, Popovic M, Navarro J, Fonoff E, Hamani C, et al. Reconstruction of reaching movement trajectories using electrocorticographic signals in humans. PLoS ONE. 2017;12:e0182542 pubmed publisher
    ..An adaptive selection of frequency bands was used for movement classification and prediction. This demonstrates the efficacy of developing a real-time brain-machine interface for arm movements with as few as eight ECoG electrodes. ..
  13. Song I, Orosz I, Chervoneva I, Waldman Z, Fried I, Wu C, et al. Bimodal coupling of ripples and slower oscillations during sleep in patients with focal epilepsy. Epilepsia. 2017;58:1972-1984 pubmed publisher
    ..Phase-event amplitude coupling between ripples and sleep oscillations may be useful to distinguish pathologic and physiologic events in patients with frontal and parietal SOZ. ..