herpes zoster vaccine


Summary: An attenuated vaccine used to prevent and/or treat HERPES ZOSTER, a disease caused by HUMAN HERPESVIRUS 3.

Top Publications

  1. Winthrop K, Wouters A, Choy E, Soma K, Hodge J, Nduaka C, et al. The Safety and Immunogenicity of Live Zoster Vaccination in Patients With Rheumatoid Arthritis Before Starting Tofacitinib: A Randomized Phase II Trial. Arthritis Rheumatol. 2017;69:1969-1977 pubmed publisher
    ..Vaccination appeared to be safe in all of the patients except 1 patient who lacked preexisting VZV immunity. ..
  2. Yawn B. Post-shingles neuralgia by any definition is painful, but is it PHN?. Mayo Clin Proc. 2011;86:1141-2 pubmed publisher
  3. . Varicella and herpes zoster vaccines: WHO position paper, June 2014. Wkly Epidemiol Rec. 2014;89:265-87 pubmed
  4. Weinberg A, Canniff J, Rouphael N, Mehta A, Mulligan M, Whitaker J, et al. Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults. J Immunol. 2017;199:604-612 pubmed publisher
    ..This may underlie their inability to contain VZV reactivation and prevent the development of HZ. ..
  5. Li S, Sullivan N, Rouphael N, Yu T, Banton S, Maddur M, et al. Metabolic Phenotypes of Response to Vaccination in Humans. Cell. 2017;169:862-877.e17 pubmed publisher
    ..Our approach is broadly applicable to study human immunity and can help to identify predictors of efficacy as well as mechanisms controlling immunity to vaccination. ..
  6. Dayan R, Peleg R. Herpes zoster - typical and atypical presentations. Postgrad Med. 2017;129:567-571 pubmed publisher
    ..We discuss the epidemiology, pathophysiology, diagnosis and management of Herpes Zoster, typical and atypical presentations. ..
  7. Jacobson J. Residents' role in immunizing adults: rationale, opportunity, obstacles, and strategies. Virtual Mentor. 2012;14:23-9 pubmed publisher
  8. Williams W, Lu P, O Halloran A, Bridges C, Pilishvili T, Hales C, et al. Noninfluenza vaccination coverage among adults - United States, 2012. MMWR Morb Mortal Wkly Rep. 2014;63:95-102 pubmed
  9. Gershon A. Is chickenpox so bad, what do we know about immunity to varicella zoster virus, and what does it tell us about the future?. J Infect. 2017;74 Suppl 1:S27-S33 pubmed publisher
    ..There are strong indications that the best way to control disease and spread of this virus is by vaccination against both. ..

More Information


  1. Dommasch E, Joyce C, Mostaghimi A. Trends in Nationwide Herpes Zoster Emergency Department Utilization From 2006 to 2013. JAMA Dermatol. 2017;153:874-881 pubmed publisher
    ..Per-visit and total costs increased across all age groups. Vaccination may be associated with a reduction of ED utilization. Further research is required to confirm these results and examine the drivers of increased ED costs. ..
  2. Chen L, Arai H, Chen L, Chou M, Djauzi S, Dong B, et al. Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific. BMC Infect Dis. 2017;17:213 pubmed publisher
    ..Given the strong rationale for prevention, most adult immunisation guidelines include HZ vaccine, yet it remains underused. We urge all stakeholders to give higher priority to adult immunisation in general and HZ in particular. ..
  3. Horn J, Damm O, Greiner W, Hengel H, Kretzschmar M, Siedler A, et al. Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany - a mathematical modelling study. BMC Med. 2018;16:3 pubmed publisher
  4. Verschoor C, Lelic A, Parsons R, Evelegh C, Bramson J, Johnstone J, et al. Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents. J Infect Dis. 2017;216:191-197 pubmed publisher
    ..In summary, these data improve our understanding of vaccine responsiveness for those in long-term care, suggesting that certain risk factors are associated with a greater likelihood of vaccine failure. ..
  5. Wright W, Morrell E, Lee J, CUELLAR N, White P. Comparison of immunization rates of adults ages 65 years and older managed within two nurse practitioner-owned clinics with national immunization rates. J Am Assoc Nurse Pract. 2017;29:384-391 pubmed publisher
    ..and pertussis; influenza; pneumococcal polysaccharide vaccine 23; pneumococcal conjugate vaccine 13; and herpes zoster vaccine). One hundred and fifty females (70.8%) and 62 males (29.2%) met inclusion criteria...
  6. Williams W, Lu P, O Halloran A, Bridges C, Kim D, Pilishvili T, et al. Vaccination coverage among adults, excluding influenza vaccination - United States, 2013. MMWR Morb Mortal Wkly Rep. 2015;64:95-102 pubmed
  7. Johnson R, Rice A. Clinical practice. Postherpetic neuralgia. N Engl J Med. 2014;371:1526-33 pubmed publisher
  8. Cohen J. Clinical practice: Herpes zoster. N Engl J Med. 2013;369:255-63 pubmed publisher
  9. Naidus E, Damon L, Schwartz B, Breed C, Liu C. Experience with use of Zostavax(®) in patients with hematologic malignancy and hematopoietic cell transplant recipients. Am J Hematol. 2012;87:123-5 pubmed publisher
  10. Wilson J. In the clinic. Herpes zoster. Ann Intern Med. 2011;154:ITC31-15; quiz ITC316 pubmed publisher
    ..Readers who are interested in these primary resources for more detail can consult www.acponline.org, http://pier.acponline.org, and other resources referenced within each issue of In the Clinic. ..