oxytetracycline

Summary

Summary: A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.

Top Publications

  1. ncbi Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river
    Dong Li
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, China
    Environ Toxicol Chem 27:80-6. 2008
  2. pmc Antibiotic resistance characteristics of environmental bacteria from an oxytetracycline production wastewater treatment plant and the receiving river
    Dong Li
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, China
    Appl Environ Microbiol 76:3444-51. 2010
  3. ncbi Indirect evidence of transposon-mediated selection of antibiotic resistance genes in aquatic systems at low-level oxytetracycline exposures
    Charles W Knapp
    Department of Civil, Environmental and Architectural Engineering, University of Kansas, Lawrence, Kansas 66045, USA
    Environ Sci Technol 42:5348-53. 2008
  4. pmc Genetics of Streptomyces rimosus, the oxytetracycline producer
    Hrvoje Petkovic
    Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
    Microbiol Mol Biol Rev 70:704-28. 2006
  5. doi A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot
    G J Wassink
    Department of Biological Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, West Midlands, UK
    Prev Vet Med 96:93-103. 2010
  6. pmc Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase
    Wenjun Zhang
    Department of Chemical and Biomolecular Engineering, University of California Los Angeles, 5531 Boelter Hall, 420 Westwood Plaza, Los Angeles, CA 90095
    Appl Environ Microbiol 72:2573-80. 2006
  7. ncbi Validation of a high-performance liquid chromatography method for the determination of oxytetracycline, tetracycline, chlortetracycline and doxycycline in bovine milk and muscle
    A L Cinquina
    Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana, Via Appia Nuova 1411, 00178 Rome, Italy
    J Chromatogr A 987:227-33. 2003
  8. pmc Heterologous expression of the oxytetracycline biosynthetic pathway in Myxococcus xanthus
    D Cole Stevens
    Department of Chemistry, Syracuse University, Syracuse, New York 132441, USA
    Appl Environ Microbiol 76:2681-3. 2010
  9. doi Occurrence of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracycline
    Erin E Seyfried
    Department of Civil and Environmental Engineering, University of Wisconsin at Madison, 3204 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706, USA
    Microb Ecol 59:799-807. 2010
  10. pmc Lettuce for human consumption collected in Costa Rica contains complex communities of culturable oxytetracycline- and gentamicin-resistant bacteria
    Cesar Rodriguez
    Abteilung Mikrobiologie, Fachbereich Biologie chemie, Universitat Osnabruck, Barbarastrasse 11, D 49069 Osnabruck, Germany
    Appl Environ Microbiol 72:5870-6. 2006

Research Grants

Detail Information

Publications266 found, 100 shown here

  1. ncbi Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river
    Dong Li
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, China
    Environ Toxicol Chem 27:80-6. 2008
    This study investigated the occurrence and fate of oxytetracycline (OTC) and its related substances, 4-epi-oxytetracycline (EOTC), alpha-apo-oxytetracycline (alpha-apo-OTC), and beta-apo-oxytetracycline (beta-apo-OTC), in a wastewater ..
  2. pmc Antibiotic resistance characteristics of environmental bacteria from an oxytetracycline production wastewater treatment plant and the receiving river
    Dong Li
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, China
    Appl Environ Microbiol 76:3444-51. 2010
    We characterized the bacterial populations in surface water receiving effluent from an oxytetracycline (OTC) production plant...
  3. ncbi Indirect evidence of transposon-mediated selection of antibiotic resistance genes in aquatic systems at low-level oxytetracycline exposures
    Charles W Knapp
    Department of Civil, Environmental and Architectural Engineering, University of Kansas, Lawrence, Kansas 66045, USA
    Environ Sci Technol 42:5348-53. 2008
    ..To examine this issue, 15 mesocosms containing pristine surface water were treated with oxytetracycline (OTC) for 56 days at five levels (0, 5, 20, 50, and 250 microg L(-1)), and six tetracycline-resistance genes (..
  4. pmc Genetics of Streptomyces rimosus, the oxytetracycline producer
    Hrvoje Petkovic
    Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia
    Microbiol Mol Biol Rev 70:704-28. 2006
    ..Streptomyces rimosus is arguably the best-characterized industrial streptomycete as the producer of oxytetracycline and other tetracycline antibiotics...
  5. doi A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot
    G J Wassink
    Department of Biological Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, West Midlands, UK
    Prev Vet Med 96:93-103. 2010
    ..We conclude that prompt parenteral and topical antibacterial treatment of sheep lame with ID and FR reduced the prevalence and incidence of these infectious conditions and led to improved health, welfare and productivity...
  6. pmc Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase
    Wenjun Zhang
    Department of Chemical and Biomolecular Engineering, University of California Los Angeles, 5531 Boelter Hall, 420 Westwood Plaza, Los Angeles, CA 90095
    Appl Environ Microbiol 72:2573-80. 2006
    ..To this end, we have sequenced the gene cluster of oxytetracycline (oxy and otc genes) PKS genes from Streptomyces rimosus...
  7. ncbi Validation of a high-performance liquid chromatography method for the determination of oxytetracycline, tetracycline, chlortetracycline and doxycycline in bovine milk and muscle
    A L Cinquina
    Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana, Via Appia Nuova 1411, 00178 Rome, Italy
    J Chromatogr A 987:227-33. 2003
    ..7-129.9 micro/kg for all compounds in milk and muscle, respectively. The detection capability (CCbeta) was in the range 117.2-131.3 microg/kg and 114.9-133.1 microg/kg for all compounds in milk and muscle, respectively...
  8. pmc Heterologous expression of the oxytetracycline biosynthetic pathway in Myxococcus xanthus
    D Cole Stevens
    Department of Chemistry, Syracuse University, Syracuse, New York 132441, USA
    Appl Environ Microbiol 76:2681-3. 2010
    ..However, a "universal" host is needed for this experiment. Herein, we show that Myxococcus xanthus is a potential "universal" host for heterologous expression of polyketide biosynthetic gene clusters...
  9. doi Occurrence of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracycline
    Erin E Seyfried
    Department of Civil and Environmental Engineering, University of Wisconsin at Madison, 3204 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706, USA
    Microb Ecol 59:799-807. 2010
    ..The purpose of this study was to determine if oxytetracycline (OTC) use in aquaculture facilities increased the detection frequency (i.e...
  10. pmc Lettuce for human consumption collected in Costa Rica contains complex communities of culturable oxytetracycline- and gentamicin-resistant bacteria
    Cesar Rodriguez
    Abteilung Mikrobiologie, Fachbereich Biologie chemie, Universitat Osnabruck, Barbarastrasse 11, D 49069 Osnabruck, Germany
    Appl Environ Microbiol 72:5870-6. 2006
    ..Farmers from nine sampling sites regularly apply commercial formulations containing gentamicin, oxytetracycline, streptomycin, or a combination of them without being able to indicate how often and how much of these ..
  11. ncbi Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi
    S Townson
    Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, UK
    Ann Trop Med Parasitol 94:801-16. 2000
    The activity against filarial parasites of the antibiotics rifampicin, oxytetracycline and chloramphenicol was examined...
  12. doi Kinetics of Coxiella burnetii excretion in a commercial dairy sheep flock after treatment with oxytetracycline
    Ianire Astobiza
    NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Department of Animal Health, Berreaga 1, 48160 Derio, Bizkaia, Spain
    Vet J 184:172-5. 2010
    ..In the following breeding cycle, 75% of the animals in the flock were double treated with oxytetracycline (OTC) at days +100 and +120 of gestation, while the remaining 25% of the animals were kept as untreated ..
  13. ncbi ssDNA aptamers that selectively bind oxytetracycline
    Javed H Niazi
    College of Life Sciences and Biotechnology, Korea University, Anam Dong, Seongbuk gu, Seoul 136 701, South Korea
    Bioorg Med Chem 16:1254-61. 2008
    Single stranded DNA aptamers that bind with high affinity and specificity to the oxytetracycline (OTC) were identified by selection from an oligonucleotide library of 10(15) molecules...
  14. doi Man-tailored biomimetic sensor of molecularly imprinted materials for the potentiometric measurement of oxytetracycline
    Felismina T C Moreira
    REQUIMTE, Instituto Superior de Engenharia do Porto, R Dr Antonio Bernardino de Almeida, 431, 4200 072 Porto, Portugal
    Biosens Bioelectron 26:566-74. 2010
    A novel biomimetic sensor for the potentiometric transduction of oxytetracycline is presented. The artificial host was imprinted in methacrylic acid and/or acrylamide based polymers...
  15. ncbi [Residues of tetracycline and quinolones in wild fish living around a salmon aquaculture center in Chile]
    Antonia Fortt Z
    Oceana Oficina para la América del Sur y la Antártica, Santiago, Chile AFZ
    Rev Chilena Infectol 24:14-8. 2007
    ..More studies are needed in Chile to determine the relevance of these findings for human and animal health and the environment to regulate this use of antibiotics...
  16. doi Fabrication of an oxytetracycline molecular-imprinted sensor based on the competition reaction via a GOD-enzymatic amplifier
    Jianping Li
    College of Chemistry and Bioengineering, Guilin University of Technology, Jiangan Road, Guangxi, 541004, China
    Biosens Bioelectron 26:2097-101. 2011
    A highly sensitive molecular-imprinted polymer sensor (MIP sensor) for ultratrace oxytetracycline (OTC) determination was prepared based on the competition reaction between template molecule OTC and glucose oxidase (GOD)-labeled OTC (GOD-..
  17. doi Molecularly imprinted sensor based on an enzyme amplifier for ultratrace oxytetracycline determination
    Jianping Li
    College of Chemistry and Bioengineering, Guilin University of Technology, Guangxi, 541004, China
    Anal Chem 82:6074-8. 2010
    ..for preparing highly sensitive, molecularly imprinted sensors based on enzyme amplifiers was proposed for oxytetracycline (OTC) determination...
  18. pmc Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection
    R D Ayling
    Veterinary Laboratories Agency Weybridge, Woodham Lane, Addlestone, Surrey KT15 3NB, United Kingdom
    Antimicrob Agents Chemother 49:5162-5. 2005
    ..Of the antimicrobials used most widely in Africa, oxytetracycline and tilmicosin were effective, while the isolates were resistant to tylosin...
  19. ncbi Sorption of oxytetracycline to iron oxides and iron oxide-rich soils
    Raquel A Figueroa
    University of Connecticut, Environmental Engineering Program, 261 Glenbrook Road, U 2037, Storrs, Connecticut 06269 2037, USA
    Environ Sci Technol 39:6664-71. 2005
    The sorption interactions of oxytetracycline with goethite, hematite, and two iron oxide-rich soils were investigated using batch sorption experiments...
  20. doi Degradation of tetracycline and oxytetracycline by crude lignin peroxidase prepared from Phanerochaete chrysosporium--a white rot fungus
    Xianghua Wen
    State Key Joint Laboratory of Environment Simulation and Pollution Control, Department of Environmental Science and Engineering, Tsinghua University, Beijing 100084, PR China
    Chemosphere 75:1003-7. 2009
    ..This study chose tetracycline (TC) and oxytetracycline (OTC) as examples of pharmaceuticals...
  21. ncbi Comparison of the antimicrobial tolerance of oxytetracycline-resistant heterotrophic bacteria isolated from hospital sewage and freshwater fishfarm water in Belgium
    G Huys
    Laboratory of Microbiology, University of Gent, Ghent, Belgium
    Syst Appl Microbiol 24:122-30. 2001
    ..to investigate the relationship between antimicrobial tolerance and taxonomic diversity among the culturable oxytetracycline-resistant (Ot(r)) heterotrophic bacterial population in two Belgian aquatic sites receiving wastewater either ..
  22. doi Photodegradation of oxytetracycline in aqueous by 5A and 13X loaded with TiO2 under UV irradiation
    Chun Zhao
    Key Laboratory of Yangtze River Water Environment, Ministry of Education, Tongji University, Shanghai 200092, PR China
    J Hazard Mater 176:884-92. 2010
    The photocatalysis degradation, mineralization and detoxification of oxytetracycline (OTC) in aqueous were investigated by 5A and 13X zeolite with nano-TiO(2) loaded under UV light...
  23. doi A novel colorimetric aptasensor using gold nanoparticle for a highly sensitive and specific detection of oxytetracycline
    Yeon Seok Kim
    College of Life Sciences and Biotechnology, Korea University, Anam Dong, Seongbuk gu, Seoul 136 701, South Korea
    Biosens Bioelectron 26:1644-9. 2010
    ..a novel colorimetric aptasensor using gold nanoparticles for highly sensitive and specific detection of oxytetracycline (OTC), one of the most common antibacterial agents...
  24. doi Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes
    Lan Yu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China
    Enzyme Microb Technol 50:318-24. 2012
    b>Oxytetracycline (OTC) is a widely used antibiotic, which is commercially produced by Streptomyces rimosus. The type II minimal polyketide synthases (minimal PKS) genes of the oxytetracycline biosynthesis cluster in S...
  25. ncbi Effect of steroidal and non-steroidal anti-inflammatory drugs in combination with long-acting oxytetracycline on non-specific immunity of calves suffering from enzootic bronchopneumonia
    Dariusz Bednarek
    Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Partyzantow 57, 24 100, Pulawy, Poland
    Vet Microbiol 96:53-67. 2003
    The aim of this paper was to compare the effect of flumethasone and meloxicam in combination with oxytetracycline on clinical and immunological parameters of calves suffering from enzootic bronchopneumonia...
  26. doi Oxytetracycline attenuates allergic airway inflammation in mice via inhibition of the NF-κB pathway
    Xinxin Ci
    Institute of Zoonoses, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, Jilin 130062, People s Republic of China
    J Clin Immunol 31:216-27. 2011
    b>Oxytetracycline has been used in the treatment of acute and chronic bronchial inflammation and infectious asthma. However, its potential use for non-infectious asthma has not yet been studied...
  27. ncbi Influence of flumequine and oxytetracycline on the resistance of the European eel against the parasitic swimbladder nematode Anguillicola crassus
    M H van der Heijden
    Department of Fish Culture and Fisheries, Wageningen Agricultural University, The Netherlands
    Vet Immunol Immunopathol 52:127-34. 1996
    The effect of the antibacterial drugs flumequine (FQ) and oxytetracycline (OTC) on the defence system of the European eel (Anguilla anguilla L...
  28. pmc Comparison of side effects of oxytetracycline and talc pleurodesis: an experimental study
    Alper Gozubuyuk
    Department of Thoracic Surgery, Kirikkale University, School of Medicine, Kirikkale, Turkey
    J Cardiothorac Surg 5:128. 2010
    ..Talc is the most commonly used agent for the treatment, with rare, serious complications reported. Oxytetracycline pleurodesis in clinical practice has been described in a few studies, but literature reveals no experimental ..
  29. pmc Oxytetracycline biosynthesis
    Lauren B Pickens
    Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095, USA
    J Biol Chem 285:27509-15. 2010
    b>Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. It is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products...
  30. doi Insights into aquatic toxicities of the antibiotics oxytetracycline and ciprofloxacin in the presence of metal: complexation versus mixture
    Yu Zhang
    Key Laboratory of Industrial Ecology and Environmental Engineering, Ministry of Education, School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China
    Environ Pollut 166:48-56. 2012
    ..The complexation of two antibiotics, oxytetracycline and ciprofloxacin, with three heavy metals, copper, zinc, and cadmium, was verified by spectroscopic ..
  31. doi In vitro synergistic effects of baicalin with oxytetracycline and tetracycline against Staphylococcus aureus
    Pavel Novy
    Department of Crop Sciences and Agroforestry, Institute of Tropics and Subtropics, Czech University of Life Sciences Prague, Kamycka 129, 16521 Prague 6 Suchdol, Czech Republic
    J Antimicrob Chemother 66:1298-300. 2011
    In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus.
  32. ncbi The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community
    W D Kong
    Research Center for Eco Environmental Sciences, Soil Environment of Sciences, Chinese Academy of Sciences, Beijing, China
    Environ Pollut 143:129-37. 2006
    ..The widely used veterinary antibiotic oxytetracycline (OTC), Cu and their combination on soil microbial community function were assessed with the Biolog method...
  33. doi Molecular characterizations of chloramphenicol- and oxytetracycline-resistant bacteria and resistance genes in mariculture waters of China
    Hongyue Dang
    Centre for Bioengineering and Biotechnology, China University of Petroleum East China, 66 Changjiang West Road, Qingdao 266555, China
    Mar Pollut Bull 58:987-94. 2009
    ..gene cat II, cat IV or floR could be detected in most of the multidrug-resistant isolates, and the oxytetracycline-resistance gene tet(B), tet(D), tet(E) or tet(M) could also be detected for most of the isolates...
  34. ncbi Preliminary investigation on the environmental occurrence and effects of antibiotics used in aquaculture in Italy
    Giorgia Mary Lalumera
    Environment Research Group, Department of Structural and Functional Biology DBSF, University of Insubria, Via J H Dunant, 3 21100 Varese, Italy
    Chemosphere 54:661-8. 2004
    ..on the most pertinent and diffuse fish diseases and their related therapies, the presence of flumequine and oxytetracycline in sediments sampled from two trout farms and three sea-bass farms and in their surrounding environments was ..
  35. ncbi The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil
    Thomas L Ter Laak
    IRAS Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 2, P O Box 80176, 3508 TD Utrecht, The Netherlands
    Environ Toxicol Chem 25:904-11. 2006
    ..the soil sorption of three antimicrobial agents--sulfachloropyridazine (SCP), tylosin (TYL), and oxytetracycline (OTC)--was investigated. Their respective sorption coefficients in two agricultural soils ranged from 1...
  36. ncbi Influence of naringenin on oxytetracycline mediated oxidative damage in rat liver
    Leelavinothan Pari
    Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar 608002, Tamilnadu, India
    Basic Clin Pharmacol Toxicol 98:456-61. 2006
    ..was carried out to evaluate the effect of naringenin on antioxidant and lipid peroxidation status in liver of oxytetracycline-intoxicated rats...
  37. ncbi Effects of European foulbrood treatment regime on oxytetracycline levels in honey extracted from treated honeybee (Apis mellifera) colonies and toxicity to brood
    Helen M Thompson
    National Bee Unit, Central Science Laboratory, Sand Hutton, York, UK
    Food Addit Contam 22:573-8. 2005
    This study aimed to assess oxytetracycline (OTC) residue levels in honey up to 12 weeks after treatment of honeybee colonies with two methods of application (in liquid sucrose and in powdered icing sugar)...
  38. pmc A clinical trial comparing parenteral oxytetracyline and enrofloxacin on time to recovery in sheep lame with acute or chronic footrot in Kashmir, India
    J Kaler
    The School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire LE12 5RD, UK
    BMC Vet Res 8:12. 2012
    ..footrot were allocated to one of three treatments using stratified random sampling: long acting parenteral oxytetracycline, long acting parenteral enrofloxacin and topical application of potassium permanganate solution (a ..
  39. pmc New Mg2+-dependent oxytetracycline resistance determinant tet 34 in Vibrio isolates from marine fish intestinal contents
    Lisa Nonaka
    Center for Marine Environmental Studies CMES, Ehime University, Matsuyama 790 8577, Japan
    Antimicrob Agents Chemother 46:1550-2. 2002
    A new oxytetracycline (OTC) resistance (Otc(r)) determinant, Tet 34, was cloned from chromosomal DNA of Vibrio sp. no. 6 isolated from intestinal contents of cultured yellowtail (Seriola quinqueradiata)...
  40. ncbi Effects of dietary soyabean meal, inulin and oxytetracycline on intestinal microbiota and epithelial cell stress, apoptosis and proliferation in the teleost Atlantic salmon (Salmo salar L.)
    Anne Marie Bakke-McKellep
    Aquaculture Protein Centre, CoE, Norway
    Br J Nutr 97:699-713. 2007
    ..fishmeal (FM) as the sole protein source, responses to extracted SBM or the prebiotic inulin, with or without oxytetracycline (OTC) inclusion, were studied following a 3-week feeding trial...
  41. doi Randomized clinical trial of long-acting oxytetracycline, foot trimming, and flunixine meglumine on time to recovery in sheep with footrot
    J Kaler
    Department of Biological Sciences, University of Warwick, Coventry, UK
    J Vet Intern Med 24:420-5. 2010
    ..Internationally, foot trimming is used by most farmers, and parenteral antibacterials by some, to treat sheep with footrot. Nonsteroidal anti-inflammatory drugs (NSAID) are sometimes used. No clinical trials have compared these treatments...
  42. ncbi Efficacy of intramuscular treatment of beef cows with oxytetracycline to reduce mastitis and to increase calf growth
    C A Lents
    Department of Animal Science, Oklahoma Agricultural Experiment Station, Stillwater 74078, USA
    J Anim Sci 80:1405-12. 2002
    ..multiparous Angus x Hereford cows were used to determine the efficacy of intramuscular treatment with oxytetracycline to reduce the incidence of mastitis-causing bacteria, decrease milk somatic cell counts (SCC), and increase ..
  43. doi Noncovalent interaction of oxytetracycline with the enzyme trypsin
    Zhenxing Chi
    Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, China America CRC for Environment and Health, Shandong Province, 27 Shanda South Road, Jinan 250100, P R China
    Biomacromolecules 11:2454-9. 2010
    b>Oxytetracycline (OTC) is a kind of widely used veterinary drugs. The residue of OTC in the environment (e.g., animal food, soils, surface, and groundwater) is potentially harmful...
  44. ncbi Disappearance of oxytetracycline resistance genes in aquatic systems
    Christina A Engemann
    Department of Civil, Environmental, and Architectural Engineering, University of Kansas, Lawrence, KS, USA
    FEMS Microbiol Lett 263:176-82. 2006
    ..Treatments included simulated sunlight with 0, 25, and 250 microg L(-1) nominal oxytetracycline (OTC) levels, respectively, and 'dark' conditions...
  45. doi Interactions of oxytetracycline with a smectite clay: a spectroscopic study with molecular simulations
    Ludmilla Aristilde
    Environmental Geochemistry Group, LGIT, University of Grenoble 1, CNRS, F 38041 Grenoble, France
    Environ Sci Technol 44:7839-45. 2010
    ..mechanisms of tetracycline antibiotics on smectite clays as a function of pH, we probed the interactions of oxytetracycline (OTC) with Na-montmorillonite (MONT) using X-ray diffraction (XRD), infrared (IR), and solid-state nuclear ..
  46. ncbi Field assessment of oxytetracycline exposure to the freshwater macrophytes Egeria densa Planch. and Ceratophyllum demersum L
    M L Hanson
    Department of Environment and Geography, University of Manitoba, 118 Isbister Building, Winnipeg, Manitoba R3T 2N2, Canada
    Environ Pollut 141:434-42. 2006
    ..densa and Ceratophyllum demersum were exposed to nominal concentrations of 0, 5, 20, 50, and 250 microg/L oxytetracycline (n=3), plus 20 microg/L oxytetracycline amended with additional nitrogen (N) and phosphorus (P)...
  47. doi Clinical, histologic, and bacteriologic findings in dairy cows with digital dermatitis (footwarts) one month after topical treatment with lincomycin hydrochloride or oxytetracycline hydrochloride
    Steven L Berry
    Department of Animal Science, College of Agricultural and Environmental Sciences, University of California Davis, Davis, CA 95616, USA
    J Am Vet Med Assoc 237:555-60. 2010
    To compare the effectiveness of lincomycin and oxytetracycline for treatment of digital dermatitis (DD) in dairy cows through gross visual examination, histologic evaluation, and bacteriologic evaluation.
  48. doi Effects of two simulated oxytetracycline dosing regimens on horizontal transfer of antimicrobial resistance plasmids in an in vitro pharmacodynamic model
    Brian V Lubbers
    Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA
    Am J Vet Res 72:877-83. 2011
    To evaluate the impact of oxytetracycline exposure on horizontal transfer of an antimicrobial resistance plasmid.
  49. ncbi Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus
    Stuart C Findlow
    School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton, SO16 7PX, United Kingdom
    Biochemistry 42:8423-33. 2003
    ..and dynamics of the ACP involved in the biosynthesis of the commonly prescribed polyketide antibiotic, oxytetracycline (otc)...
  50. pmc Lack of lysosomal fusion with phagosomes containing Ehrlichia risticii in P388D1 cells: abrogation of inhibition with oxytetracycline
    M Y Wells
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Ohio State University, Columbus 43210 1092
    Infect Immun 56:3209-15. 1988
    ..or cationized ferritin to document phagosome-lysosome (P-L) fusion in untreated cells and cells treated with oxytetracycline. Regardless of the marker used, P-L fusion was generally not observed in E...
  51. ncbi Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline
    Charles K Nfon
    Liverpool School of Tropical Medicine and Faculty of Veterinary Science, University of Liverpool, Liverpool, United Kingdom
    Am J Trop Med Hyg 76:67-72. 2007
    ..Using Onchocerca ochengi in cattle, an analog of human onchocerciasis, we have previously shown that oxytetracycline is macrofilaricidal, and protective immunity exists naturally in a subset of animals termed putatively immune...
  52. ncbi P-glycoprotein-mediated transport of oxytetracycline in the Caco-2 cell model
    J Schrickx
    Department of Veterinary Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    J Vet Pharmacol Ther 30:25-31. 2007
    ..b>Oxytetracycline (OTC) has been used for decennia in veterinary medicine for its extensive spectrum of antimicrobial activity...
  53. pmc Incidence, distribution, and spread of tetracycline resistance determinants and integron-associated antibiotic resistance genes among motile aeromonads from a fish farming environment
    A S Schmidt
    Danish Veterinary Laboratory, DK 1790 Copenhagen V
    Appl Environ Microbiol 67:5675-82. 2001
    ..Environ. Microbiol. 66:4908-4915, 2000), the predominant resistance phenotype (37%) being a combined oxytetracycline (OTC) and sulphadiazine/trimethoprim resistance...
  54. ncbi Fate of oxytetracycline in streams receiving aquaculture discharges: model simulations
    Peter E Rose
    River Studies Center, University of Wisconsin, La Crosse, Wisconsin 54601, USA
    Environ Toxicol Chem 24:40-50. 2005
    The potential aquatic fate of oxytetracycline (OTC) in streams receiving discharge from fish hatcheries was examined using the Water-Quality Analysis Simulation Program (WASP, Ver 6.1) model. The modeled 4...
  55. ncbi Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil
    Marco De Liguoro
    Dipartimento di Sanita Pubblica, Patologia Comparata ed Igiene Veterinaria, Facolta di Medicina Veterinaria, Universita degli Studi di Padova, Agripolis, I 35020 PD, Legnaro, Italy
    Chemosphere 52:203-12. 2003
    ..Because of their biological effects, antibiotics are regarded as potential micropollutants. The levels of oxytetracycline and tylosin over time were followed in faeces, bedding and manure, and then in the soil of a manured field ..
  56. ncbi Effects of prostaglandin E1, melatonin, and oxytetracycline on lipid peroxidation, antioxidant defense system, paraoxonase (PON1) activities, and homocysteine levels in an animal model of spinal cord injury
    Cahide Topsakal
    Department of Neurosurgery, Firat University School of Medicine, Elazig, Turkey
    Spine (Phila Pa 1976) 28:1643-52. 2003
    Investigation of the effects of prostaglandin E1, melatonin, and oxytetracycline on lipid peroxidation, antioxidant and paraoxonase activities, and homocysteine levels in an experimental model of spinal cord injury.
  57. ncbi Rapid pleurodesis in symptomatic malignant pleural effusion
    Erkan Yildirim
    Department of Thoracic Surgery, Ankara Numune Education and Research Hospital, Ankara, Turkey
    Eur J Cardiothorac Surg 27:19-22. 2005
    ..The objective of the study was to see whether a rapid method of pleurodesis was superior to the standard protocol in patients with symptomatic malignant pleural effusion...
  58. ncbi Effects of melatonin and oxytetracycline in autologous intraperitoneal ovary transplantation in rats
    Ekrem Sapmaz
    Department of Obstetrics and Gynecology, Faculty of Medicine, Firat University, Elazig Turkey
    Neuro Endocrinol Lett 24:350-4. 2003
    To comparatively investigate the effects melatonin and oxytetracycline as antioxidants on autologous intraperitoneal ovary transplantation in rats.
  59. ncbi The bryophyte Fontinalis antipyretica Hedw. bioaccumulates oxytetracycline, flumequine and oxolinic acid in the freshwater environment
    Raphael Delepee
    Ecole Nationale Veterinaire de Nantes, UMR INRA ENVN Chimiothérapie Aquacole et Environnement, B P 40706, 44307 Nantes Cedex 03, France
    Sci Total Environ 322:243-53. 2004
    ..Oxolinic acid (OA), flumequine (FLU) and oxytetracycline (OTC) are commonly used antibacterial agents...
  60. ncbi Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens
    M Singh
    Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences, CSK Himachal Pradesh Agricultural University, Himachal Pradesh, India
    J Vet Sci 6:197-200. 2005
    The pharmacokinetic profile of orally administered oxytetracycline (10 mg/kg body weight) was studied 7 days post oral treatment of Piper longum (15 mg equivalent/kg) in White Leghorn hens (2-2.8 kg)...
  61. ncbi Investigating the molecular interactions of oxytetracycline in clay and organic matter: insights on factors affecting its mobility in soil
    Pankaj Kulshrestha
    Departments of Chemistry and Geology, University at Buffalo, The State University of New York, Buffalo, New York 14260, USA
    Environ Sci Technol 38:4097-105. 2004
    The interactions of oxytetracycline with model clay adsorbents were investigated as a function of suspension pH...
  62. ncbi Determination of the distribution coefficient (log Kd) of oxytetracycline, tylosin A, olaquindox and metronidazole in manure
    Marie Louise Loke
    Department of Analytical and Pharmaceutical Chemistry, Royal Danish School of Pharmacy, Copenhagen
    Chemosphere 48:351-61. 2002
    ..This corresponds with the negative log Kow values of these antibiotics. Tylosin (log Kow = 1.63) and oxytetracycline (log Kow = -1.12) sorp relatively strongly to the manure particles and have log Kd values between 1.5 and 2.0...
  63. ncbi Growth performance and immune response of two commercial broiler strains fed diets containing Lactobacillus cultures and oxytetracycline under heat stress conditions
    I Zulkifli
    Department of Animal Science, Universiti Putra, Malaysia, Selangor
    Br Poult Sci 41:593-7. 2000
    1. Hubbard x Hubbard (HH) and Shaver x Shaver (SS) chicks given a dietary supplement of either 50 mg/kg oxytetracycline (OTC) or 1 g/kg Lactobacillus culture (LC) were exposed to 36 +/- 1 degrees C for 3 h daily from day (d) 21 to 42. 2...
  64. ncbi Microbiological and chemical detection of incurred penicillin G, oxytetracycline, enrofloxacin and ciprofloxacin residues in bovine and porcine tissues
    A L Myllyniemi
    Department of Food Microbiology, National Veterinary and Food Research Institute, P O Box 368 Hämeentie 57, 00231 Helsinki, Finland anna liisa
    Food Addit Contam 17:991-1000. 2000
    Incurred penicillin G, oxytetracycline, enrofloxacin and ciprofloxacin residues in bovine and porcine muscle and kidney samples were analysed by microbiological and chemical methods, the former using Bacillus subtilis BGA as a test ..
  65. doi Specific detection of oxytetracycline using DNA aptamer-immobilized interdigitated array electrode chip
    Yeon Seok Kim
    School of Life Sciences and Biotechnology, Korea University, Anam Dong, Seongbuk gu, Seoul 136 701, Republic of Korea
    Anal Chim Acta 634:250-4. 2009
    An electrochemical sensing system for oxytetracycline (OTC) detection was developed using ssDNA aptamer immobilized on gold interdigitated array (IDA) electrode chip...
  66. ncbi Comparison of the effectiveness of some pleural sclerosing agents used for control of effusions in malignant pleural mesothelioma: a review of 117 cases
    A Senyigit
    Department of Chest Diseases, Faculty of Medicine, University of Dicle, Diyarbakir, Turkey
    Respiration 67:623-9. 2000
    ..We aimed to investigate the efficacy of oxytetracycline (OT), Corynebacterium parvum (CP), and nitrogen mustard (NM) in the management of pleural effusion associated ..
  67. pmc Distribution of oxytetracycline resistance plasmids between aeromonads in hospital and aquaculture environments: implication of Tn1721 in dissemination of the tetracycline resistance determinant tet A
    G Rhodes
    Freshwater Biological Association, Far Sawrey, Ambleside, Cumbria LA22 OLP, United Kingdom
    Appl Environ Microbiol 66:3883-90. 2000
    b>Oxytetracycline-resistant (OT(r)) mesophilic aeromonads were recovered from untreated hospital effluent (72 isolates) and from fish farm hatchery tanks (91 isolates) at sites within the English Lake District, Cumbria, England...
  68. ncbi In vitro susceptibilities of field isolates of Mycoplasma agalactiae to oxytetracycline, tylosin, enrofloxacin, spiramycin and lincomycin-spectinomycin
    G R Loria
    Institute Zooprofilattico, Sperimentale della Sicilia, Via Rocco Dicillo, 4 I 90129, Palermo, Sicily, Italy
    Res Vet Sci 75:3-7. 2003
    ..521; MIC(90)0.938 microg/ml) and spiramycin (MIC(50)1.583; MIC(90)2.850 microg/ml). MIC values above 1.000 microg/ml were obtained using tetracycline, tylosin and spiramycin for some M. agalactiae isolates...
  69. ncbi Eosinophils contribute to killing of adult Onchocerca ochengi within onchocercomata following elimination of Wolbachia
    Charles K Nfon
    Liverpool School of Tropical Medicine and Faculty of Veterinary Science, University of Liverpool, Pembroke Place, Liverpool L3 5QA, UK
    Microbes Infect 8:2698-705. 2006
    ..ochengi, we previously demonstrated that combined intensive and intermittent (COM) oxytetracycline treatment induces a sustained depletion of Wolbachia and is macrofilaricidal, whereas a short intensive ..
  70. pmc Influence of ileo-caecal cannulation and oxytetracycline on ileo-caecal and rectal coliform populations in pigs
    A Högberg
    Department of Animal Nutrition and Management, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Acta Vet Scand 42:435-40. 2001
    The effect of surgery (insertion of an ileo-caecal cannula) and a subsequent parenteral treatment with oxytetracycline on the ileo-caecal and rectal coliform populations in 7 Swedish Yorkshire castrates were studied...
  71. ncbi Clinical signs, computed tomographic imaging, and management of chronic otitis media/interna in dairy calves
    Jérôme Van Biervliet
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    J Vet Intern Med 18:907-10. 2004
  72. ncbi Molecular spectroscopic study on the interaction of tetracyclines with serum albumins
    Shuyun Bi
    College of Chemistry, Jilin University, Jiefang Road 119, Changchun 130023, PR China
    Spectrochim Acta A Mol Biomol Spectrosc 61:629-36. 2005
    ..The main sorts of acting force between the drugs and serum albumins were found and the action distances and the energy transfer efficiencies between donor-acceptor were calculated based on the Foster energy transference...
  73. ncbi [Microbiological method for the detection of antibiotic residues in meat using mixed-mode, reverse-phase and cation-exchange cartridge]
    Tomoko Kusano
    Tokyo Metropolitan Institute of Public Health 3 24 1, Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
    Shokuhin Eiseigaku Zasshi 45:191-6. 2004
    A microbiological method for screening of residual benzylpenicillin (PCG), oxytetracycline (OTC) and spiramycin (SPM) in meat using a single mixed mode, reversed-phase and cation-exchange cartridge was developed...
  74. ncbi Simultaneous determination of selected veterinary antibiotics in gilthead seabream (Sparus Aurata) by liquid chromatography-mass spectrometry
    R Romero-González
    Department of Analytical Chemistry, Almeria University, E 04071, Almeria, Spain
    J Chromatogr B Analyt Technol Biomed Life Sci 857:142-8. 2007
    ..drugs of different classes of antibiotics such as quinolones (oxilinic acid and flumequine), tetracyclines (oxytetracycline), sulfonamides (sulfadiazine) and trimethoprim in fish muscle and skin...
  75. ncbi Escherichia coli O157:H7 in a cohort of weaned, preconditioned range beef calves
    John R Dunn
    Louisiana State University, School of Veterinary Medicine, Skip Bertman Drive, Baton Rouge, Louisiana 70803, USA
    J Food Prot 67:2391-6. 2004
    ..29 cow-calf farms were commingled at three preconditioning sites and placed on a transition ration containing oxytetracycline (200 g/ton) for 45 days. Initial animal-level fecal point prevalence was 2...
  76. ncbi Topical treatment of digital dermatitis associated with severe heel-horn erosion in a Swedish dairy herd
    Thomas Manske
    Department of Animal Environment and Health, Section of Field Research, Swedish University of Agricultural Sciences, P O Box 234, SE 532 23, Skara, Sweden
    Prev Vet Med 53:215-31. 2002
    ..In Experiment I, topical treatments with solutions of either glutaraldehyde or oxytetracycline were compared with foot trimming and cleansing alone...
  77. pmc Changes in tetracycline susceptibility of enteric bacteria following switching to nonmedicated milk replacer for dairy calves
    John B Kaneene
    Center for Comparative Epidemiology, Michigan State University, East Lansing, Michigan 48824 1314, USA
    J Clin Microbiol 46:1968-77. 2008
    ..intervention study was conducted to determine if discontinuing use of calf milk replacer medicated with oxytetracycline results in increased tetracycline susceptibility in Salmonella and Campylobacter spp...
  78. ncbi Antimicrobial susceptibilities of Campylobacter isolated from food-producing animals on farms (1999-2001): results from the Japanese Veterinary Antimicrobial Resistance Monitoring Program
    Kanako Ishihara
    National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries 1 15 1 Tokura, Kokubunji, Tokyo 185 8511, Japan
    Int J Antimicrob Agents 24:261-7. 2004
    ..Campylobacter species showed high frequencies of resistance to oxytetracycline and dihydrostreptomycin...
  79. ncbi Analysis of tetracyclines in honey by high-performance liquid chromatography/tandem mass spectrometry
    Seu Ping Khong
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Rapid Commun Mass Spectrom 19:493-502. 2005
    ..chromatography to tandem mass spectrometry (LC/MS/MS) is described for the determination of tetracycline, oxytetracycline, doxycycline and chlortetracycline in honey...
  80. ncbi In vitro susceptibility of avian mycoplasmas to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline
    C Wang
    College of Veterinary Medicine, Mississippi State University, Mississippi State 39762-9825, USA
    Avian Dis 45:456-60. 2001
    ..avian Mycoplasma gallisepticum (MG) and Mycoplasma synoviae (MS) to enrofloxacin, sarafloxacin, tylosin, and oxytetracycline was determined by a serial broth dilution method...
  81. ncbi Antibiotic resistance and hypermutability of Escherichia coli O157 from feedlot cattle treated with growth-promoting agents
    Brigitte Lefebvre
    Centre d étude et de valorisation de la diversité microbienne, Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada J1K 2R1
    J Food Prot 68:2411-9. 2005
    ..the effect of growth-promoting agents (monensin and trenbolone acetate-estradiol) and an antibiotic (oxytetracycline) on the incidence in feedlot steers of Escherichia coli O157, including antibiotic-resistant and hypermutable ..
  82. ncbi The tetAB genes of the Corynebacterium striatum R-plasmid pTP10 encode an ABC transporter and confer tetracycline, oxytetracycline and oxacillin resistance in Corynebacterium glutamicum
    A Tauch
    Department of Genetics, University of Bielefeld, Germany
    FEMS Microbiol Lett 173:203-9. 1999
    ..An antibiotic susceptibility screening in C. glutamicum showed that the tetAB genes confer resistance to tetracycline, oxytetracycline and to the structurally and functionally unrelated beta-lactam antibiotic oxacillin.
  83. ncbi Comparison of spontaneous antibiotic resistance frequency of Salmonella Typhimurium growth in glucose amended continuous culture at slow and fast dilution rates
    W K Kim
    Department of Poultry Science, Texas A and M University College Station, Texas 77843 2472, USA
    J Environ Sci Health B 40:475-84. 2005
    ..state, samples were plated to tryptic soy agar (TSA) alone or supplemented (per ml) with 2 and 16 microg oxytetracycline, 4 and 16 microg tetracycline, 2 and 64 microg kanamycin, and 0.25 and 2 microg enrofloxacin...
  84. ncbi Flow cytometric evaluation of selected antimicrobial efficacy for clearance of Anaplasma marginale in short-term erythrocyte cultures
    J F Coetzee
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
    J Vet Pharmacol Ther 29:173-83. 2006
    ..Herein, we used flow cytometry to test the efficacy of three antimicrobials; oxytetracycline, imidocarb and enrofloxacin against Virginia (VGN) or Oklahoma (OK) A...
  85. ncbi Long-term effects of meloxicam in the treatment of respiratory disease in fattening cattle
    G M Friton
    Corporate Marketing, Boehringer Ingelheim Animal Health, D 55216 Ingelheim am Rhein, Germany
    Vet Rec 156:809-11. 2005
    ..Two hundred animals with clinical signs of brd received a single subcutaneous injection of 20 mg/kg oxytetracycline; 100 of them also received a subcutaneous injection of 0...
  86. pmc A clinical trial to assess the use of sodium hypochlorite and oxytetracycline on the healing of digital dermatitis lesions in cattle
    Luiz A F Silva
    Department of Veterinary Medicine, School of Veterinary Medicine, Universidade Federal de Goias, P O Box 131 ZIP CODE 74 001 970, Goiania, Goias, Brazil
    Can Vet J 46:345-8. 2005
    ..of this study was to evaluate the topical action of sodium hypochlorite associated with the systemic use of oxytetracycline for the treatment of wounds clinically diagnosed as bovine digital dermatitis...
  87. ncbi Growth performance and shedding of some pathogenic bacteria in feedlot cattle treated with different growth-promoting agents
    Brigitte Lefebvre
    Centre de Valorisation de la Diversité Microbienne, Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada J1K 2R
    J Food Prot 69:1256-64. 2006
    ..evaluate the effect of a growth-promoting implant (trenbolone acetate plus estradiol benzoate), monensin, and oxytetracycline on the steer performance and shedding of some foodborne pathogens...
  88. pmc A comparison of prophylactic efficacy of tilmicosin and a new formulation of oxytetracycline in feedlot calves
    Oliver C Schunich
    Feedlot Health Management Services, Bay 7 87 Elizabeth Street, Postal Bag Service 5, Okotoks, Alberta T0L 1T0
    Can Vet J 43:355-62. 2002
    ..performed under commercial feedlot conditions in western Canada to compare the administration of long-acting oxytetracycline at 30 mg/kg body weight (BW) versus tilmicosin at 10 mg/kg BW to feedlot calves upon arrival at the feedlot...
  89. ncbi Microbial inhibition by pharmaceutical antibiotics in different soils--dose-response relations determined with the iron(III) reduction test
    Sören Thiele-Bruhn
    Institute for Land Use, Soil Science Section, University of Rostock, Justus von Liebig Weg 6, D 18051 Rostock, Germany
    Environ Toxicol Chem 24:869-76. 2005
    ..increased in the order (average ED50 in parentheses) chlortetracycline (53) < sulfadimethoxine (58) < oxytetracycline (170) < sulfadiazine (190) < sulfadimidine (270) = tetracycline (270) < sulfapyridine (430), though ..
  90. ncbi Assessment and promotion of judicious antibiotic use on dairy farms in Washington State
    M J Raymond
    Communicable Disease Control Program, Tacoma Pierce County Health Department, Tacoma, WA 98418, USA
    J Dairy Sci 89:3228-40. 2006
    ..The most commonly cited drugs used for disease treatment were penicillin, ceftiofur, and oxytetracycline. Participants also indicated significant preventive uses with 28% using medicated milk replacer...
  91. ncbi Ulcerative and papillomatous digital dermatitis of the pastern region in dairy cattle: clinical and histopathological studies
    W el-Ghoul
    Department of Surgery, Anaesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
    Dtsch Tierarztl Wochenschr 108:216-22. 2001
    ..The topical application of oxytetracycline solution or benzathine penicillin powder appeared to be effective for the treatment of the ulcerative lesions...
  92. ncbi Putative quantitative trait loci associated with the probability of contracting infectious bovine keratoconjunctivitis
    E Casas
    US Meat Animal Research Center, USDA, ARS, Clay Center, NE 68933 0166, USA
    J Anim Sci 84:3180-4. 2006
    ..Although a candidate gene was identified for one of the regions of interest, further studies are needed to identify the genetic basis of resistance to the disease...
  93. ncbi Clinical efficacy of meloxicam (Metacam) and flunixin (Finadyne) as adjuncts to antibacterial treatment of respiratory disease in fattening cattle
    Gabriele M Friton
    Boehringer Ingelheim Animal Health GmbH, Ingelheim am Rhein, Germany
    Berl Munch Tierarztl Wochenschr 117:304-9. 2004
    ..On Day 0 all animals were treated with 20 mg oxytetracycline/kg body-weight (Bivatop 200) by subcutaneous injection, in conjunction with either meloxicam (0...
  94. ncbi Comparison of the efficacy of enrofloxacin, imidocarb, and oxytetracycline for clearance of persistent Anaplasma marginale infections in cattle
    Johann F Coetzee
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 5001, USA
    Vet Ther 7:347-60. 2006
    This study compared enrofloxacin and imidocarb dipropionate treatments with an oxytetracycline regimen proposed by the World Organization for Animal Health for elimination of persistent Anaplasma marginale infections in cattle...
  95. ncbi Determination of tetracycline antibiotics in salmon muscle by liquid chromatography using post-column derivatization with fluorescence detection
    Angelina L Pena
    University of Coimbra, Centre of Pharmaceutical Studies, Faculty of Pharmacy, Group of Bromatology, 3000 Coimbra, Portugal
    J AOAC Int 86:925-9. 2003
    A simple and accurate cleanup procedure using polymeric sorbent was developed for the determination of oxytetracycline (OTC) and tetracycline (TC) residues in salmon muscle...
  96. ncbi Use of antimicrobial susceptibility testing of bacterial pathogens isolated from the milk of dairy cows with clinical mastitis to predict response to treatment with cephapirin and oxytetracycline
    Peter D Constable
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana 61802, USA
    J Am Vet Med Assoc 221:103-8. 2002
    ..susceptibility testing of bacterial pathogens isolated from the milk of dairy cows with clinical mastitis were associated with duration of clinical signs or bacteriologic cure rate following treatment with cephapirin and oxytetracycline.
  97. ncbi Persistence of oxytetracycline residues in milk after the intrauterine treatment of lactating cows for endometritis
    X Tan
    Department of Veterinary Medicine, Zhejiang University, Hangzhou, People s Republic of China
    Vet Rec 161:585-6. 2007
    ..collected at one day intervals after the last dose from 31 cows that had received an intrauterine infusion of oxytetracycline once daily between one and five times...
  98. ncbi Assay and purity control of tetracycline, chlortetracycline and oxytetracycline in animal feeds and premixes by TLC densitometry with fluorescence detection
    Weng Naidong
    Laboratorium voor Farmaceutische Chemie en Analyse van Geneesmiddelen, Faculteit Farmaceutische Wetenschappen, Katholieke Universiteit Leuven, Van Evenstraat 4, B 3000 Leuven, Belgium
    J Pharm Biomed Anal 33:85-93. 2003
    ..detection are described for the assay and purity control of tetracycline (TC), chlortetracycline (CTC), and oxytetracycline (OTC) in animal feeds and premixes...
  99. ncbi Diversity of tetracycline resistance genes in bacteria from aquaculture sources in Australia
    O L Akinbowale
    Sansom Institute, School of Pharmaceutical and Medical Sciences, University of South Australia, Adelaide, SA, Australia
    J Appl Microbiol 103:2016-25. 2007
    To determine the genetic determinants responsible for tetracycline resistance in oxytetracycline resistant bacteria from aquaculture sources in Australia.
  100. ncbi Quantitative analysis of oxytetracycline and its 4-epimer in calf tissues by high-performance liquid chromatography combined with positive electrospray ionization mass spectrometry
    Marc Cherlet
    Ghent University, Faculty of Veterinary Medicine, Department of Pharmacology, Pharmacy and Toxicology, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Analyst 128:871-8. 2003
    ..b>Oxytetracycline (OTC) is one of the most important members of this antibiotic family...
  101. ncbi AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor?
    Pierre Louis Toutain
    UMR181 Physiopathologie et Toxicologie Expérimentales INRA, ENVT, 23 Chemin des Capelles, 31076 Toulouse cedex 03, France
    J Antimicrob Chemother 60:1185-8. 2007
    ..To accommodate the need for dose prediction during these novel therapeutic situations, we propose a general approach that is based on the targeted time interval over which some desired average concentration should be maintained...

Research Grants18

  1. Enhancement of antimicrobics by electrical current
    Robin Patel; Fiscal Year: 2007
    ..vitro experiments have shown that electric current can enhance the activity of aminoglycosides, quinolones or oxytetracycline against bacteria in biofilms; this has been termed the 'bioelectric effect...
  2. GROWTH PLATE CELLULAR FUNCTION FOLLOWING RADIOTHERAPY
    Timothy Damron; Fiscal Year: 2007
    ..abstract_text> ..
  3. Analysis of CD81-PGRL complex on T cells
    STEPHEN CHAPES; Fiscal Year: 2007
    ..The coordinated effect of CD81, PGRL and EP3 on T cell integrin activity measured by adhesion to or motility on ICAMs. ..
  4. GROWTH PLATE CELLULAR FUNCTION FOLLOWING RADIOTHERAPY
    Timothy Damron; Fiscal Year: 2003
    ..abstract_text> ..