foams and jellies vaginal creams

Summary

Summary: Medicated dosage forms for topical application in the vagina. A cream is a semisolid emulsion containing suspended or dissolved medication; a foam is a dispersion of a gas in a medicated liquid resulting in a light, frothy mass; a jelly is a colloidal semisolid mass of a water soluble medicated material, usually translucent.

Top Publications

  1. ncbi The effect of pH on release of PGE2 from vaginal and endocervical preparations for induction of labour: an in-vitro study
    T A Johnson
    Department of Obstetrics and Gynaecology, University of Edinburgh, UK
    Br J Obstet Gynaecol 99:877-80. 1992
  2. ncbi Awareness and practice of family planning methods in women attending gyne OPD at Nepal Medical College Teaching Hospital
    H Tuladhar
    Department of Obs Gyne, Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal
    Nepal Med Coll J 10:184-91. 2008
  3. pmc Does self-administered vaginal misoprostol result in cervical ripening in postmenopausal women after 14 days of pre-treatment with estradiol? Trial protocol for a randomised, placebo-controlled sequential trial
    K S Oppegaard
    Department of Gynaecology, Helse Finnmark, Klinikk Hammerfest, Hammerfest, Norway
    BJOG 115:917-e10. 2008
  4. ncbi Isosorbide mononitrate vaginal gel versus misoprostol vaginal gel versus Dilapan-S for cervical ripening before first trimester curettage
    Frank Chih Kang Chen
    Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Klinik fur Geburtsmedizin, Augustenburger Platz 1, Berlin, Germany
    Eur J Obstet Gynecol Reprod Biol 138:176-9. 2008
  5. pmc A combination of misoprostol and estradiol for preoperative cervical ripening in postmenopausal women: a randomised controlled trial
    K S Oppegaard
    Department of Gynaecology, Helse Finnmark, Klinikk Hammerfest, Hammerfest, Norway
    BJOG 117:53-61. 2010
  6. ncbi Comparison of isosorbide mononitrate (Mono Mack) and misoprostol (Cytotec) for cervical ripening in the first trimester missed abortion
    Matthias David
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Arch Gynecol Obstet 273:144-5. 2005
  7. ncbi ["Mixed" and "miscellaneous" vulvovaginitis: diagnostics and therapy of vaginal administration of nystatin and nifuratel]
    P Cepicky
    Gynekologicko porodnická ambulance LEVRET s r o, Praha
    Ceska Gynekol 70:232-7. 2005
  8. ncbi Thrombotic thrombocytopenic purpura induced by metronidazole vaginal gel
    Anastasia Rivkin
    Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Brooklyn, New York 11201, USA
    Pharmacotherapy 27:1058-61. 2007
  9. ncbi Men's knowledge of and attitude with respect to family planning in a suburban Nigerian community
    O O Odu
    Department of Community Medicine, College of Health Sciences, Ladoke Akintola University of Technology, Osogbo, Osun State, Nigeria
    Niger J Med 15:260-5. 2006
  10. pmc Oral misoprostol for induction of labour at term: randomised controlled trial
    Jodie M Dodd
    Department of Obstetrics and Gynaecology, University of Adelaide, Women s and Children s Hospital, North Adelaide, SA 5006, Australia
    BMJ 332:509-13. 2006

Detail Information

Publications168 found, 100 shown here

  1. ncbi The effect of pH on release of PGE2 from vaginal and endocervical preparations for induction of labour: an in-vitro study
    T A Johnson
    Department of Obstetrics and Gynaecology, University of Edinburgh, UK
    Br J Obstet Gynaecol 99:877-80. 1992
    ....
  2. ncbi Awareness and practice of family planning methods in women attending gyne OPD at Nepal Medical College Teaching Hospital
    H Tuladhar
    Department of Obs Gyne, Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal
    Nepal Med Coll J 10:184-91. 2008
    ..Efforts should be made to educate the public about the safety and convenience of modern, long-term, reversible methods of contraception among both healthcare professionals and the public...
  3. pmc Does self-administered vaginal misoprostol result in cervical ripening in postmenopausal women after 14 days of pre-treatment with estradiol? Trial protocol for a randomised, placebo-controlled sequential trial
    K S Oppegaard
    Department of Gynaecology, Helse Finnmark, Klinikk Hammerfest, Hammerfest, Norway
    BJOG 115:917-e10. 2008
    ....
  4. ncbi Isosorbide mononitrate vaginal gel versus misoprostol vaginal gel versus Dilapan-S for cervical ripening before first trimester curettage
    Frank Chih Kang Chen
    Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Klinik fur Geburtsmedizin, Augustenburger Platz 1, Berlin, Germany
    Eur J Obstet Gynecol Reprod Biol 138:176-9. 2008
    ..To compare the efficacy and safety of vaginal applications of three different principles of cervical priming prior to first trimester curettage, isosorbide mononitrate (ISMN), misoprostol and Dilapan-S, a hygroscopical cervical dilator...
  5. pmc A combination of misoprostol and estradiol for preoperative cervical ripening in postmenopausal women: a randomised controlled trial
    K S Oppegaard
    Department of Gynaecology, Helse Finnmark, Klinikk Hammerfest, Hammerfest, Norway
    BJOG 117:53-61. 2010
    ....
  6. ncbi Comparison of isosorbide mononitrate (Mono Mack) and misoprostol (Cytotec) for cervical ripening in the first trimester missed abortion
    Matthias David
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Arch Gynecol Obstet 273:144-5. 2005
    ..The objective of this study was to compare NO-donor isosorbide mononitrate to misoprostol, both applied as vaginal tablets for cervical ripening prior to first trimester curettage in patients with missed abortion...
  7. ncbi ["Mixed" and "miscellaneous" vulvovaginitis: diagnostics and therapy of vaginal administration of nystatin and nifuratel]
    P Cepicky
    Gynekologicko porodnická ambulance LEVRET s r o, Praha
    Ceska Gynekol 70:232-7. 2005
    ..The evaluation of combined and miscellaneous vulvovaginal infections incidence and their treatment with combined vaginal products containing nifuratel and nystatin...
  8. ncbi Thrombotic thrombocytopenic purpura induced by metronidazole vaginal gel
    Anastasia Rivkin
    Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Brooklyn, New York 11201, USA
    Pharmacotherapy 27:1058-61. 2007
    ..This patient had developed TTP after only one exposure to metronidazole vaginal gel. Clinicians should be aware of this life-threatening adverse reaction to a commonly prescribed drug...
  9. ncbi Men's knowledge of and attitude with respect to family planning in a suburban Nigerian community
    O O Odu
    Department of Community Medicine, College of Health Sciences, Ladoke Akintola University of Technology, Osogbo, Osun State, Nigeria
    Niger J Med 15:260-5. 2006
    ..A cross-sectional survey was conducted to determine men's knowledge of and attitude to family planning at Ganmo, a sub-urban community on the outskirts of Ilorin, Nigeria...
  10. pmc Oral misoprostol for induction of labour at term: randomised controlled trial
    Jodie M Dodd
    Department of Obstetrics and Gynaecology, University of Adelaide, Women s and Children s Hospital, North Adelaide, SA 5006, Australia
    BMJ 332:509-13. 2006
    ..To compare oral misoprostol solution with vaginal prostaglandin gel (dinoprostone) for induction of labour at term to determine whether misoprostol is superior...
  11. ncbi A clinical multicenter study comparing efficacy and tolerability of topical combination therapy with clotrimazole (Canesten, two formats) with oral single dose fluconazole (Diflucan) in vulvovaginal mycoses
    Werner Mendling
    Vivantes Klinka im Friedrichshain und Am Urban, Klinik für Gynäkologie und Geburtsmedizin, Berlin, Germany
    Mycoses 47:136-42. 2004
    ..All treatments administered were safe and well-tolerated and the number of patients experiencing adverse events was low...
  12. ncbi [Ketoconazole and clindamycin efficacy vs oral clindamycin in premature membranes rupture prevention]
    Eugenio Castillo Huerta
    Servicio de Ginecologia y Obstetricia, Ginecoobstetra certificado por el Consejo Mexicano de Ginecología y Obstetricia, Hospital Civil Dr Miguel Silva SSA de Morelia, Michoacan, Mexico
    Ginecol Obstet Mex 76:373-80. 2008
    ..Vulvovaginitis is one of the main causes of premature membrane rupture...
  13. ncbi [Indication for labor induction by prostaglandin E2 vaginal gel. Retrospective study of a continuous series of 170 patients]
    Lionel Carbillon
    Service de Gynécologie Obstétrique Hôpital Jean Verdier Assistance Publique Hôpitaux de Paris Avenue du 14 Juillet 93143 Bondy
    Presse Med 31:594-600. 2002
    ..To assess the factors of efficacy, side effects and complications following vaginal application of prostaglandin E2 (PGE2)...
  14. ncbi Estrogen and progesterone effects on transcapillary fluid dynamics
    N S Stachenfeld
    The John B Pierce Laboratory and Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Am J Physiol Regul Integr Comp Physiol 281:R1319-29. 2001
    ..05), and the PV loss during ANP infusion was attenuated (-0.9 +/- 0.2 and -0.2 +/- 0.2 ml/kg for GnRH analog-alone and E(2)-P(4) treatments, respectively). Thus the E(2)-P(4) treatment lowered CFC and reduced PV loss during ANP infusion...
  15. ncbi Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis
    P Mastromarino
    Department of Public Health Sciences, Section of Microbiology, Universita Sapienza, Rome, Italy
    Clin Microbiol Infect 15:67-74. 2009
    ..The data indicate that intravaginal administration of exogenous selected strains of lactobacilli can restore a normal vaginal microbiota and be used in treating bacterial vaginosis...
  16. ncbi A randomized study of low-dose conjugated estrogens on sexual function and quality of life in postmenopausal women
    Michael J Gast
    Wyeth Pharmaceuticals, Collegeville, PA, USA
    Menopause 16:247-56. 2009
    ..To evaluate the effects of combined vaginal and oral low-dose estrogen plus progestogen therapy (EPT) on the frequency and severity of dyspareunia, sexual function, and quality of life in recently postmenopausal women...
  17. ncbi [Antifungal effect in selected natural compounds and probiotics and their possible use in prophylaxis of vulvovaginitis]
    M Hronek
    Katedra biologických a lékarských vĕd Farmaceutické fakulty v Hradci Králové, LF UK, Praha
    Ceska Gynekol 70:395-9. 2005
    ..a survey of effective natural compounds and probiotics with antifungal activity and their possible use in vulvovaginitis as a prophylactic or therapeutic drug...
  18. ncbi Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval
    Ian Tummon
    Department of Obstetrics and Gynaecology, The University of Western Ontario, London, Ontario, Canada
    Hum Reprod 19:1116-20. 2004
    ..Vaginal application of lidocaine gel is a non-invasive alternative to lidocaine paracervical block. The goal of the present trial was to compare analgesia with lidocaine vaginal gel versus lidocaine paracervical block...
  19. ncbi Management of post-menopausal vaginal atrophy and atrophic vaginitis
    Camil Castelo-Branco
    Institut Clinic de Ginecologia, Obstetricia i Neonatologia, Hospital Clinic, Facultad de Medicina, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Maturitas 52:S46-52. 2005
    ..This review focuses on the changes involved in vaginal aging and efforts to present a synopsis of the pathophysiology and therapy of atrophic vaginitis and vaginal atrophy...
  20. ncbi Efficacy of the combination of 2 g oral tinidazole and acidic buffering vaginal gel in comparison with vaginal clindamycin alone in bacterial vaginosis: a randomized, investigator-blinded, controlled trial
    Massimo Milani
    R and D Mipharm, Via B Quaranta 12, 20141 Milan, Italy
    Eur J Obstet Gynecol Reprod Biol 109:67-71. 2003
    ..To evaluate the efficacy of tinidazole (T) (Trimonase, Mipharm, Italy) and an acidic vaginal gel (Miphil) (M) in comparison with vaginal clindamycin (CL) (Cleocin Pharmacia Upjohn) in BV...
  21. ncbi Progesterone vaginal gel for the reduction of recurrent preterm birth: primary results from a randomized, double-blind, placebo-controlled trial
    J M O'Brien
    Perinatal Diagnostic Center, Central Baptist Hospital, Lexington, Kentucky, USA
    Ultrasound Obstet Gynecol 30:687-96. 2007
    ..The objective of this trial was to determine whether prophylactic administration of vaginal progesterone reduces the risk of preterm birth in women with a history of spontaneous preterm birth...
  22. ncbi Preinduction cervical ripening with prostaglandin E2 at preterm
    Nir Melamed
    Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Hospital, Petah Tiqva, Israel
    Acta Obstet Gynecol Scand 87:63-7. 2008
    ..To evaluate the efficacy of prostaglandin E2 (PGE2) for cervical ripening at preterm and to identify factors predicting ripening failure...
  23. ncbi Single-dose sertaconazole vaginal tablet treatment of vulvovaginal candidiasis
    Peng Hui Wang
    Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taiwan, ROC
    J Chin Med Assoc 69:259-63. 2006
    ..The aim of the present study was to evaluate the efficacy, acceptability, and safety of single-dose sertaconazole vaginal tablet (500 mg) treatment compared with conventional 3-dose econazole vaginal tablet (150 mg) treatment for VVC...
  24. ncbi The efficacy and safety of a single dose of polyhexamethylene biguanide gynaecologic solution versus a seven-dose regimen of vaginal clindamycin cream in patients with bacterial vaginosis
    M Minozzi
    Institute of Gynecology and Obstetrics, University La Sapienza, Rome, Italy
    Eur Rev Med Pharmacol Sci 12:59-65. 2008
    ....
  25. ncbi A universal combination treatment for vaginitis
    Jacob Bornstein
    Department of Obstetrics and Gynecology, Western Galilee Hospital, Nahariya, Israel
    Gynecol Obstet Invest 65:195-200. 2008
    ..We compared a novel vaginal tablet consisting of 100 mg of clotrimazole and 100 mg of metronidazole ('Clo-Met') to a 100-mg clotrimazole tablet in the treatment of vaginitis...
  26. pmc A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women
    L Van Damme
    Institute of Tropical Medicine, Antwerp, Belgium
    Sex Transm Infect 76:126-30. 2000
    ..5% and 4%) over a 2 week period of daily exposure in two cohorts of healthy sexually abstinent women (one in London, UK, and the other in Antwerp, Belgium)...
  27. pmc Development and evaluation of acid-buffering bioadhesive vaginal tablet for mixed vaginal infections
    Mohd Aftab Alam
    Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi 110062, India
    AAPS PharmSciTech 8:E109. 2007
    ..In the in vitro antimicrobial study it was found that the acid-buffering bioadhesive tablet produces better antimicrobial action than marketed intravaginal drug delivery systems (Infa-V, Candid-V and Canesten 1)...
  28. pmc Effect of a single vaginal administration of levonorgestrel in Carraguard gel on the ovulatory process: a potential candidate for "dual protection" emergency contraception
    Vivian Brache
    PROFAMILIA, Biomedical Research Department, P O Box 1053, Santo Domingo 10401, Dominican Republic
    Contraception 76:111-6. 2007
    ..75 mg of levonorgestrel (CARRA/LNG gel) administered in a single dose at different stages of follicle development over subsequent follicle rupture and hormonal levels...
  29. pmc Effect of thiolated polymers to textural and mucoadhesive properties of vaginal gel formulations prepared with polycarbophil and chitosan
    Erdal Cevher
    Faculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul University, 34116, Istanbul, Turkey
    AAPS PharmSciTech 9:953-65. 2008
    ..Stability of CLM was preserved during the 3 month stability analysis under controlled room temperature and accelerated conditions...
  30. ncbi A phase II randomized controlled trial to evaluate the safety and efficacy of Praneem polyherbal vaginal tablets compared with betadine vaginal pessary in women with symptoms of abnormal vaginal discharge
    Sudha Salhan
    Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
    Asia Pac J Public Health 21:461-8. 2009
    ..Thus, the study indicates the efficacy of Praneem for the treatment of AVD and provides a rationale for planning a further Phase III study on a larger sample size for definitive conclusions...
  31. ncbi Comparison of dermatopharmacokinetic vs. clinicial efficacy methods for bioequivalence assessment of miconazole nitrate vaginal cream, 2% in humans
    Lynn K Pershing
    Department of Dermatology, University of Utah School of Medicine, Salt Lake City 84132, USA
    Pharm Res 19:270-7. 2002
    ..To compare the dermatopharmacokinetic vs. clinical trial methods for bioequivalence assessment of two miconazole nitrate vaginal cream, 2% products...
  32. pmc Luteal phase bleeding after IVF cycles: comparison between progesterone vaginal gel and intramuscular progesterone and correlation with pregnancy outcomes
    Sami Jabara
    Department of Obstetrics and Gynecology, Texas Tech University, Lubbock, Texas, USA
    J Exp Clin Assist Reprod 6:6. 2009
    ..To compare luteal phase bleeding and pregnancy outcomes in normogonadotropic patients receiving progesterone vaginal gel (PVG) or intramuscular progesterone (IMP) injections...
  33. ncbi 17 alpha-hydroxyprogesterone caproate versus intravaginal progesterone in IVF-embryo transfer cycles: a prospective randomized study
    Vittorio Unfer
    A G UN CO, Obstetrics and Gynecology Centre, via G Cassiani, 15 00155 Rome, Italy
    Reprod Biomed Online 9:17-21. 2004
    ..The data showed that 17-HPC administered every 3 days appears to be more effective in providing luteal support in comparison to intra-vaginal progesterone...
  34. ncbi Cervical ripening with the Foley catheter
    A Cromi
    Department of Obstetrics and Gynecology, University of Insubria Ospedale F Del Ponte, Varese, Italy
    Int J Gynaecol Obstet 97:105-9. 2007
    ..To evaluate maternal and neonatal outcomes in a large series of patients undergoing cervical ripening with a Foley catheter...
  35. ncbi Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial
    Lut Van Damme
    Institute of Tropical Medicine, Antwerp, Belgium
    Lancet 360:971-7. 2002
    ..Results of studies of its effectiveness in prevention of HIV-1 infection in women have been inconclusive. We aimed to assess effectiveness of this vaginal gel...
  36. ncbi Urinary tract infections in pregnant women with bacterial vaginosis
    S H Sharami
    Department of Obstetrics and Gynecology, Guilan University of Medical Sciences, Rasht, Iran
    J Obstet Gynaecol 27:252-4. 2007
    ..8%) of those without. Bacterial vaginosis was associated with an increased risk of UTIs (odds ratio (OR) 3.05; 95% CI: 1.47-6.33). Pregnant women with bacterial vaginosis are at increased risk for UTIs...
  37. ncbi Investigation of product quality between extemporaneously compounded progesterone vaginal suppositories and an approved progesterone vaginal gel
    Vorapann Mahaguna
    PharmaForm, LLC, Austin, TX 78758, USA
    Drug Dev Ind Pharm 30:1069-78. 2004
    ..This data indicates that pharmacy compounded delivery systems for progesterone should be used with caution...
  38. ncbi [Preterm delivery in a patient with frontal lobe brain tumor]
    Nedo Cutura
    Ginekolosko akuserska klinika, Narodni Front, Beograd, Srbija
    Vojnosanit Pregl 66:830-2. 2009
    ..The aim of this paper was to emphasize the importance of such pregnancy expert control and completion...
  39. pmc Progesterone replacement with vaginal gel versus i.m. injection: cycle and pregnancy outcomes in IVF patients receiving vitrified blastocysts
    Daniel B Shapiro
    Reproductive Biology Associates, 1100 Johnson Ferry Road, Suite 200, Atlanta, GA 30342, USA
    Hum Reprod 29:1706-11. 2014
    ..Does the type of luteal support affect pregnancy outcomes in recipients of vitrified blastocysts?..
  40. ncbi Phase I safety study of Praneem polyherbal vaginal tablet use among HIV-uninfected women in Pune, India
    Smita N Joshi
    National AIDS Research Institute, Epidemiology Department, MIDC, Bhosari, Pune, Maharashtra, India
    Trans R Soc Trop Med Hyg 99:769-74. 2005
    ..There were no serious adverse events. Praneem polyherbal tablets were found to be safe for once daily intravaginal use for 14 consecutive days in sexually active HIV-uninfected women and a Phase II study may be taken up as a priority...
  41. ncbi Efficacy of vitamin C vaginal tablets in the treatment of bacterial vaginosis: a randomised, double blind, placebo controlled clinical trial
    Eiko E Petersen
    Scientific Department, Polichem SA, Lugano, Switzerland
    Arzneimittelforschung 61:260-5. 2011
    ..0001). Both Vit. C and placebo were well tolerated and no differences in safety profile were evident between groups. The results support an effective and safe use of silicon-coated Vit. C vaginal tablets in the management of BV...
  42. ncbi The topical microbicide PRO 2000 protects against genital herpes infection in a mouse model
    N Bourne
    Division of Infectious Diseases, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Infect Dis 180:203-5. 1999
    ..Furthermore, the 4% gel provided significant protection even when viral challenge was delayed until 60 min after treatment. This is the first report to show that PRO 2000 can protect against infection with an STD pathogen in vivo...
  43. ncbi [Comparative efficacy of vaginal insert and dinoprostone gel for cervical ripening at term in current practice]
    C Denoual-Ziad
    Service Gynécologie Obstétrique et Médecine de la Reproduction, CHU, Caen
    J Gynecol Obstet Biol Reprod (Paris) 34:62-8. 2005
    ..To compare efficiency for slow release vaginal insert and vaginal gel in current practice...
  44. ncbi Induced labour with prostaglandin E2 in different parity groups after premature rupture of membranes
    A A Sobande
    College of Medicine and Medical Sciences, King Khalid University, Abha, Saudi Arabia
    East Mediterr Health J 9:309-15. 2003
    ..Prostaglandin E2 may be used with care for labour induction in women with PROM at term, even grand multiparas, unless there is history of previous caesarean delivery...
  45. pmc High-risk human papillomavirus is associated with HIV acquisition among South African female sex workers
    Bertran Auvert
    CESP INSERM UVSQ U1018, Villejuif, France
    Infect Dis Obstet Gynecol 2011:692012. 2011
    ..Mounting evidence suggests an association between human papillomavirus (HPV) and HIV acquisition. This study aimed to explore this association among South African female sex workers (FSWs)...
  46. ncbi Dose-ranging phase 1 study of TMC120, a promising vaginal microbicide, in HIV-negative and HIV-positive female volunteers
    Vicky A Jespers
    Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 44:154-8. 2007
    ..To evaluate the short-term safety, tolerability, and systemic exposure of a vaginal microbicide gel containing the nonnucleoside reverse transcriptase inhibitor TMC120...
  47. ncbi Endometrial safety of ultra-low-dose Vagifem 10 microg in postmenopausal women with vaginal atrophy
    L S G Ulrich
    Copenhagen University Hospital Rigshospitalet, Department of Gynecology and Obstetrics, Copenhagen, Denmark
    Climacteric 13:228-37. 2010
    ..The objective of the study was to evaluate the endometrial safety of a 10 microg estradiol vaginal tablet in the treatment of vaginal atrophy in postmenopausal women...
  48. ncbi Microparticulated anti-HIV vaginal gel: in vitro-in vivo drug release and vaginal irritation study
    Arkendu Chatterjee
    Department of Pharmaceutics, Himalayan Pharmacy Institute, Majhitar, Rangpo, Sikkim, India
    Pharm Dev Technol 16:466-73. 2011
    ..On the basis of a pharmacokinetic study of MBVG4 (containing ZMP: Carbopol 1:4), it was found to have better bioavailability, larger AUC and T(max) in comparison to an oral pure suspension of AZT...
  49. ncbi Comparative uterine effects on ovariectomized rats after repeated treatment with different vaginal estrogen formulations
    Juan López-Belmonte
    Farma Cros Ibérica, SL, C Castilla La Mancha 7, Pol Ind Camporrosso, 02520 Chinchilla de Montearagón, Albacete, Spain
    Maturitas 72:353-8. 2012
    ..This study was designed to compare the uterotrophic effects of a new estrogen vaginal formulation (0.005% estriol vaginal gel) and other existing topical treatments (Ovestinon(®) and Colpotrofin(®))...
  50. ncbi The practicability and surgeons' subjective experiences with vaginal danazol before an operative hysteroscopy
    Pasquale Florio
    Department of Pediatrics, Obstetrics and Reproductive Medicine, Section of Obstetrics and Gynecology, University of Siena, Siena, Italy
    Steroids 77:528-33. 2012
    ..Vaginal danazol adequately prepares the endometrium for an operative hysteroscopy by thinning the endometrium effectively with few side effects and little impact on the metabolic parameters...
  51. ncbi [Local combined therapy of vaginal infections by nifuratel-nistatin]
    Mahira Jahic
    Sluzba za zdravstvenu zastitu zena, Dom zdravlja Tuzla s poliklinikom z Dr Mustafa Sehović, Tuzla, Bosna i Hercegovina
    Med Glas (Zenica) 7:86-8. 2010
    ..Bacterial vaginitis was cured in 29 (71%) patients during this tharapy. Local vaginal combined therapy of nifuratel and nistatin is eficient in patients with vaginitis caused by fungi and Trichomonas vaginalis too...
  52. ncbi Expanded safety study of Praneem polyherbal vaginal tablet among HIV-uninfected women in Pune, India: a phase II clinical trial report
    S N Joshi
    National AIDS Research Institute, G 73, MIDC, Post Box 1895, Bhosari, Pune 411026, India
    Sex Transm Infect 84:343-7. 2008
    ..Praneem, a candidate vaginal microbicide with reported anti-HIV and contraceptive properties was evaluated for its long-term safety through a double-blind, placebo-controlled, randomised phase II trial...
  53. ncbi A randomized, double-blind, placebo-controlled Phase II extended safety study of two Invisible Condom formulations in Cameroonian women
    Francois Xavier Mbopi-Keou
    Laboratoire de Santé Hygiène Mobile, Ministry of Public Health and Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
    Contraception 81:79-85. 2010
    ....
  54. ncbi A randomized, multiple-dose parallel study to compare the pharmacokinetic parameters of synthetic conjugated estrogens, A, administered as oral tablet or vaginal cream
    Rupinder K Bhamra
    Teva Branded Pharmaceuticals USA, Woodcliff Lake, NJ, USA
    Menopause 18:393-9. 2011
    ..625 mg SCE-A/g) when administered at intervals (1 g once daily for 7 d, then twice weekly) over a 27-day period as compared with the pharmacokinetic profile of 0.3 mg SCE-A tablets administered once daily orally for 27 days...
  55. ncbi Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention
    Ariane van der Straten
    Women s Global Health Imperative, RTI International, Department of Medicine, University of California San Francisco, USA
    AIDS 26:F13-9. 2012
    ....
  56. ncbi Distribution of a vaginal gel (Invisible Condom) before, during and after simulated sexual intercourse and its persistence when delivered by two different vaginal applicators: a magnetic resonance imaging study
    Rabeea F Omar
    Centre de recherche en infectiologie de l Université Laval, Centre Hospitalier Universitaire de Quebec Centre Hospitalier de l Universite Laval, Quebec, QC, Canada G1V 4G2
    Contraception 77:447-55. 2008
    ..The persistence of the gel was evaluated up to 24 h after its administration...
  57. ncbi Pre-clinical validation of a vaginal cream containing copaiba oil (reproductive toxicology study)
    C S Lima
    Programa de Pós Graduação em Biodiversidade Tropical, Laboratório de Pesquisa em Fármacos, Universidade Federal do Amapá, Rod JK, Km 02, CEP 68902 330, Macapá, Amapa, Brazil
    Phytomedicine 18:1013-23. 2011
    ..Thus, it is concluded that the vaginal cream containing 2.5% copaiba oleoresin is safe during gestation, in female rats (Rattus norvegicus) of the Wistar strain...
  58. ncbi A comparative study of the therapeutic effects of the Zataria multiflora vaginal cream and metronidazole vaginal gel on bacterial vaginosis
    M Simbar
    School of Midwifery, Shahid Beheshti Medical Science University, Tehran, Iran
    Phytomedicine 15:1025-31. 2008
    ..multiflora vaginal cream are similar to metronidazole vaginal gel on BV. Therefore it could be an appropriate choice to BV treatment for those interested in herbal medicines or those affected by side effects of metronidazole...
  59. ncbi A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: design, in vitro and 'in vivo' evaluation
    Lei Wang
    Department of Pharmaceutics, Shenyang Pharmaceutical University, 110016 Shenyang, People s Republic of China
    Int J Pharm 350:181-7. 2008
    ..Even after 24h of administration in vagina of rats, 17% of the original employed drug was retained on the vaginal tissue. Our study may provide a potential vaginal tablet formulation of ketoconazole against Candida albicans...
  60. ncbi A randomized, placebo-controlled trial to assess the safety and acceptability of use of carraguard vaginal gel by heterosexual couples in Thailand
    Peter H Kilmarx
    National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Sex Transm Dis 35:226-32. 2008
    ..To determine the safety and acceptability of use of Carraguard, a carrageenan-derived candidate microbicide gel, during sexual intercourse in women and men...
  61. ncbi Effectiveness of vaginal tablets containing lactobacilli versus pH tablets on vaginal health and inflammatory cytokines: a randomized, double-blind study
    R Hemalatha
    Clinical Microbiology and Immunology, National Institute of Nutrition, Hyderabad, 500007, India
    Eur J Clin Microbiol Infect Dis 31:3097-105. 2012
    ..Vaginal neutral sphingomyelinase activity was not modified in either group. Vaginal tablets containing lactobacilli can cure BV and reduce vaginal inflammatory response...
  62. ncbi A randomized controlled trial of a new ovule formulation of ornidazole for the treatment of bacterial vaginosis
    E Baloglu
    Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Ege, Izmir, Turkey
    J Clin Pharm Ther 28:131-6. 2003
    ..To compare the efficacy of 500 mg ornidazole vaginal ovules (VO) and vaginal tablets (VT) in the treatment of bacterial vaginosis...
  63. ncbi Indicated labor induction with vaginal prostaglandin E2 increases the risk of cesarean section even in multiparous women with no previous cesarean section
    Avi Ben-Haroush
    Perinatal Division, WHO Collaborating Center for Perinatal Care, Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel
    J Perinat Med 32:31-6. 2004
    ..To evaluate the impact of induction of labor with vaginal tablets of prostaglandin E2 on the rate of cesarean section (CS), and to identify possible predictors of successful vaginal delivery...
  64. pmc Microbicides and HIV: A Review and an update
    Smriti Naswa
    Department of Skin VD, Medical College, Vadodara, Gujarat, India
    Indian J Sex Transm Dis 33:81-90. 2012
    ..It also enumerates various approaches in pipeline like antimicrobial peptides, aptamers, flavonoids, small interfering RNAs and DNAs, and bioengineered lactic acid bacilli...
  65. ncbi A phase I comparative postcoital testing study of three concentrations of C31G
    Christine K Mauck
    CONRAD, Eastern Virginia Medical School, 1611 North Kent Street, Suite 806, Arlington, VA 22209, USA
    Contraception 70:227-31. 2004
    ..5%, 1.0% and 1.7%, administered as a 3.5-mL dose of a vaginal gel to prevent sperm from entering mid-cycle cervical mucus. Irritation of the genitalia and acceptability were also assessed...
  66. ncbi Induction of labor with prostaglandin E2 in women with previous cesarean section and unfavorable cervix
    Yariv Yogev
    Perinatal Division and WHO Collaborating Center, Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tikva 49100, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Obstet Gynecol Reprod Biol 116:173-6. 2004
    ..To study the pregnancy outcome of induction of labor with prostaglandin E2 (PGE2) in women with one previous lower segment cesarean section...
  67. ncbi An approach to evaluate the efficacy of vaginal misoprostol administered for a rapid management of first trimester spontaneous onset incomplete abortion, in comparison to surgical curettage
    Bijan Patua
    Department of Gynecology and Obstetrics, North Bengal Medical College, Darjeeling, India
    Arch Gynecol Obstet 288:1243-8. 2013
    ....
  68. ncbi Intramuscular progesterone versus 8% Crinone vaginal gel for luteal phase support for day 3 cryopreserved embryo transfer
    Daniel J Kaser
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Fertil Steril 98:1464-9. 2012
    ..To compare outcomes after intramuscular progesterone (IMP) or 8% Crinone vaginal gel for luteal support for day 3 cryopreserved embryo transfer (CET)...
  69. ncbi Safety and acceptability of 6% cellulose sulfate vaginal gel applied four times per day for 14 days
    Anderson S Doh
    l Hôpital Gynéco Obstétrique et Pédiatrique de Yaoundé, Yaounde, Cameroon
    Contraception 76:245-9. 2007
    ..Six percent cellulose sulfate (CS) is a vaginal gel that has been in development as a microbicide...
  70. ncbi Drug delivery by the intravaginal route
    A D Woolfson
    School of Pharmacy, The Queen s University of Belfast, Northern Ireland, UK
    Crit Rev Ther Drug Carrier Syst 17:509-55. 2000
    ..Drug release mechanisms and absorption pathways are reviewed with respect to a range of therapeutic and prophylactic indications for intravaginal delivery...
  71. ncbi Termination of pregnancy in patients with previous cesarean section
    Chafika Mazouni
    Department of Obstetrics and Gynecology, Conception Hospital, 13385 Marseille, France
    Contraception 73:244-8. 2006
    ..To evaluate the safety and efficacy of termination of pregnancy using mifepristone and misosprostol at more than 15 weeks' gestation in patients with uterine scar due to previous cesarean section...
  72. ncbi Effects of acute administration of natural progesterone on peripheral vascular responsiveness in healthy postmenopausal women
    G Mercuro
    Institute of Cardiology and Department of Obstetrics and Gynecology, University of Cagliari, Sardinia, Italy
    Am J Cardiol 84:214-8. 1999
    ..Consideration must be given to the hypothesis that the addition of progestin may attenuate the beneficial effects of unopposed estrogen replacement therapy in postmenopausal women...
  73. pmc Women's experiences with oral and vaginal pre-exposure prophylaxis: the VOICE-C qualitative study in Johannesburg, South Africa
    Ariane van der Straten
    Women s Global Health Imperative, RTI International, San Francisco, California, United States of America Center for AIDS Prevention Studies, Department of Medicine, UCSF, San Francisco, California, United States of America
    PLoS ONE 9:e89118. 2014
    ..Using a socio-ecological framework (SEF), we explored socio-cultural and contextual factors that influenced participants' experience of daily vaginal gel and oral tablet regimens in VOICE...
  74. ncbi Metronidazole with Lactacyd vaginal gel in bacterial vaginosis
    Ditas Cristina D Decena
    University Santo Tomas Hospital, Manila, Philippines
    J Obstet Gynaecol Res 32:243-51. 2006
    ..To assess the efficacy and tolerability of lactic acid (Lactacyd vaginal gel; LVG) when given as an adjunct to metronidazole in the treatment of bacterial vaginosis (BV) among Filipino patients...
  75. ncbi Comparison of prostaglandin E2 tablets or Foley catheter for labour induction in grand multiparas
    M I Al-Taani
    Department of Obstetrics and Gynaecology, Queen Alia Military Hospital, Royal Medical Services, Amman, Jordan
    East Mediterr Health J 10:547-53. 2004
    ..For grand multiparas, PGE2 vaginal tablets may be preferable for ripening the cervix as well as for labour induction...
  76. ncbi User-identified gel characteristics: a qualitative exploration of perceived product efficacy of topical vaginal microbicides
    Kathleen M Morrow
    Centers for Behavioral and Preventive Medicine, Department of Psychiatry and Human Behavior, The Miriam Hospital and Warren Alpert Medical School of Brown University, CORO West, Suite 309, 164 Summit Ave, Providence, RI, 02906, USA
    Arch Sex Behav 43:1459-67. 2014
    ..When a microbicide is approved for use, providers should educate users to anticipate and understand their sensory experiences; improving users' experience can maximize adherence and product effectiveness...
  77. ncbi Research on the development of bioadhesive vaginal tablets containing 5-fluorouracil
    Ileana Cojocaru
    Discipline of Pharmaceutical Technology, Faculty of Pharmacy, University of Medicine and Pharmacy Grigore T Popa, Iasi
    Rev Med Chir Soc Med Nat Iasi 117:263-7. 2013
    ..The results are in favor of formulations F1, F2 containing 20-30% Carbopol 71 and of 37-47% Microcelac...
  78. ncbi Effect of long-term local or systemic hormone replacement therapy on post-menopausal mood disturbances. Influences of socio-economic and personality factors
    A Cagnacci
    Institute of Obstetrics and Gynecology, University of Modena, Italy
    Maturitas 31:111-6. 1999
    ..To clarify the effect exerted by hormone replacement therapy (HRT) versus socio-economic and personality factors in improving postmenopausal mood disorders...
  79. ncbi Induction of labour in nulliparous and multiparous women: a UK, multicentre, open-label study of intravaginal misoprostol in comparison with dinoprostone
    A A Calder
    Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, UK
    BJOG 115:1279-88. 2008
    ..To compare the efficacy and safety of a 25-microgram vaginal tablet of misoprostol (APL202) with dinoprostone (3-mg vaginal tablet) in cervical ripening and labour induction...
  80. pmc Ultra-low-dose estriol and lactobacilli in the local treatment of postmenopausal vaginal atrophy
    U Jaisamrarn
    Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Climacteric 16:347-55. 2013
    ..03 mg in combination with viable Lactobacillus acidophilus KS400 (Gynoflor(®) vaginal tablets) in the short-term therapy and to investigate the long-term maintenance dose in the treatment of vaginal atrophy...
  81. pmc An evaluation of methods to improve the reporting of adherence in a placebo gel trial in Andhra Pradesh, India
    Sharon A Abbott
    Population Council, New York, NY, USA
    AIDS Behav 17:2222-36. 2013
    ..Compliance to IVRS was low, despite familiarity with mobile phone technology. Additional explorations with other populations are needed...
  82. ncbi Design of tenofovir-UC781 combination microbicide vaginal gels
    Patrick F Kiser
    Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112 5820, USA
    J Pharm Sci 101:1852-64. 2012
    ..The approach described herein provides a rational schema to design and evaluate vaginal gels for use as microbicides...
  83. ncbi [Evaluation of an estrogen vaginal cream for the treatment of dyspareunia: a double-blind randomized trial]
    Sylvie Bazin
    Service d Obstétrique Gynécologie, Centre Hospitalier Universitaire de Quebec
    J Obstet Gynaecol Can 33:838-43. 2011
    ..Our objective was to assess the short-term effect of an estrogen cream on symptoms associated with provoked vestibulodynia...
  84. pmc MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments
    Craig W Hendrix
    Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    PLoS ONE 8:e55013. 2013
    ....
  85. ncbi Preparation of cycles for cryopreservation transfers using estradiol patches and Crinone 8% vaginal gel is effective and does not need any monitoring
    C Banz
    Department of Gynecology and Obstetrics, University Hospital, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Eur J Obstet Gynecol Reprod Biol 103:43-7. 2002
    ..The estradiol serum level did not predict success. In conclusion, this method of endometrial preparation is comfortable for patients and monitoring is unnecessary...
  86. ncbi Vaginal gel formulation based on theaflavin derivatives as a microbicide to prevent HIV sexual transmission
    Jie Yang
    School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
    AIDS Res Hum Retroviruses 28:1498-508. 2012
    ....
  87. ncbi Progesterone vaginal ring versus vaginal gel for luteal support with in vitro fertilization: a randomized comparative study
    Laurel Stadtmauer
    Jones Institute for Reproductive Medicine, Norfolk, Virginia 23507, USA
    Fertil Steril 99:1543-9. 2013
    ..To compare the efficacy and safety of luteal phase support in IVF with a progesterone (P) vaginal ring or gel (VR or VG)...
  88. pmc Women with pregnancies had lower adherence to 1% tenofovir vaginal gel as HIV preexposure prophylaxis in CAPRISA 004, a phase IIB randomized-controlled trial
    Lynn T Matthews
    Massachusetts General Hospital, Division of Infectious Disease, Center for Global Health, Boston, Massachusetts, USA
    PLoS ONE 8:e56400. 2013
    ..Maximizing the benefit of periconception pharmacologic HIV risk-reduction requires an understanding of the links between pregnancy and adherence to this prevention strategy...
  89. ncbi Evaluation of the efficacy and safety of hyaluronic acid vaginal gel to ease vaginal dryness: a multicenter, randomized, controlled, open-label, parallel-group, clinical trial
    Junya Chen
    Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China
    J Sex Med 10:1575-84. 2013
    ..Estrogen-based treatments have been shown to be effective; however, many patients are reluctant to use such formulations due to health concerns, hence the need to assess the efficacy of acceptable alternatives...
  90. doi Acceptability of coitally-associated versus daily use of 1% tenofovir vaginal gel among women in Pune, India
    Sanjay Mehendale
    National Institute of Epidemiology, R 127, 3rd Avenue, Tamil Nadu Housing Board, Ayapakkam, Chennai 600077, India
    Int Health 4:63-9. 2012
    ..Leakage was a problem that requires attention. Positioning of the product in a setting such as India where the majority of decision-making is done by men would need extensive and systematic education of men. ..
  91. ncbi [Gynecological aspects of allogenic stem cell transplantation--incidence, risk factors and preventive strategies--description of two clinical cases and literature review]
    Tomasz Rechberger
    II Katedra i Klinika Ginekologii UM w Lublinie, Polska
    Ginekol Pol 84:807-10. 2013
    ..After 6 weeks a follow up revealed complete healing of the vaginal canal and both patients resumed uneventful sexual intercourses. A literature review of preventive strategies for vaginal GVHD was also presented...
  92. ncbi Neuroendocrine effects of different estradiol-progestin regimens in postmenopausal women
    M Stomati
    Department of Obstetrics and Gynecology, University of Pisa, Italy
    Maturitas 28:127-35. 1997
    ..Vasomotor and behavioral effects were evaluated by using the Kupperman score, while changes in plasma endorphin (beta-END) levels were used as marker of neuroendocrine effects...
  93. pmc Efficacy and tolerability of fitostimoline (vaginal cream, ovules, and vaginal washing) and of benzydamine hydrochloride (tantum rosa vaginal cream and vaginal washing) in the topical treatment of symptoms of bacterial vaginosis
    F Boselli
    Department of Obstetrics and Gynecology, University Hospital, 4121 Modena, Italy
    ISRN Obstet Gynecol 2012:183403. 2012
    ..All the treatments were well tolerated, with only minor local adverse events infrequently reported. The results of this study confirmed that gynaecological Fitostimoline is a safe and effective topical treatment for BV...
  94. pmc Development and evaluation of a thermosensitive vaginal gel containing raltegravir+efavirenz loaded nanoparticles for HIV prophylaxis
    Abhijit A Date
    School of Pharmacy and Health Professions, Creighton University, Omaha, NE 68178, USA
    Antiviral Res 96:430-6. 2012
    ..These data demonstrate the potential of antiretroviral NP-embedded vagina gels for long-term vaginal pre-exposure prophylaxis of heterosexual HIV-1 transmission...
  95. ncbi Effectiveness and safety of a new vaginal misoprostol product specifically labeled for cervical ripening and labor induction
    Jose Guilherme Cecatti
    Department of Obstetrics and Gynecology, School of Medical Sciences FCM, University of Campinas, SP, Brazil
    Acta Obstet Gynecol Scand 85:706-11. 2006
    ....
  96. ncbi Prostaglandin E vaginal gel to treat dystocia in spontaneous labour: a multicentre randomised placebo-controlled trial
    Lawrence W Oppenheimer
    Department of Obstetrics and Gynaecology, University of Ottawa, Ottawa Hospital General Campus, Rm 8420, Ottawa, Ontario, Canada K1H 8L6
    BJOG 112:612-8. 2005
    ..To test the safety and efficacy of prostaglandin E(2) (PgE(2)) as a treatment for dystocia in spontaneous labour...
  97. ncbi Distribution of a 3.5-mL (1.0%) C31G vaginal gel using magnetic resonance imaging
    Kurt T Barnhart
    Center for Reproductive Medicine and Surgery, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Contraception 71:357-61. 2005
    ..Repeat application of the gel may be necessary if intercourse has not occurred within the first few hours after initial insertion...
  98. ncbi In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials
    Deborah Tien
    Biosyn, Inc, Huntingdon Valley, PA 19006, USA
    AIDS Res Hum Retroviruses 21:845-53. 2005
    ....
  99. pmc Potential role of tenofovir vaginal gel for reduction of risk of herpes simplex virus in females
    Dhs Tan
    Divisions of Infectious Diseases, St Michael s Hospital, University, Health Network, and University of Toronto, Toronto, Canada
    Int J Womens Health 4:341-50. 2012
    ..This article reviews the currently available data for tenofovir as an anti-herpes agent, as well as unanswered questions about delivery systems, drug formulation, rectal administration, drug resistance, and clinical applications...
  100. ncbi Recurrent bacterial vaginosis: the use of maintenance acidic vaginal gel following treatment
    J D Wilson
    Department of Genitourinary Medicine, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK janet_d wilson nhs uk
    Int J STD AIDS 16:736-8. 2005
    ..4 per woman/year, and this was reduced to 0.6 recurrences per woman/year. As there are few effective therapies for women with recurrent BV, we feel this offers an option that can currently be used in clinical practice...
  101. ncbi The therapeutic effect of a new ultra low concentration estriol gel formulation (0.005% estriol vaginal gel) on symptoms and signs of postmenopausal vaginal atrophy: results from a pivotal phase III study
    Antonio Cano
    Pediatrics Obstetrics and Gynecology Department, Valencia University, HU Dr Preset, Valencia, Spain
    Menopause 19:1130-9. 2012
    ..005% estriol vaginal gel), providing an ultra low dose of estriol per application (50 μg), for the local treatment of postmenopausal vaginal atrophy...

Research Grants32

  1. Vaginal Gel to Enhance Lubrication & Sperm Function
    JOANNA ELLINGTON; Fiscal Year: 2003
    ....
  2. Vaginal Ring for Preventing Bacterial Vaginosis
    THOMAS RAY MOENCH; Fiscal Year: 2010
    ..The ring will likely be useful for women with frequent episodes of symptomatic BV, and especially useful for preventing BV during pregnancy. ) ..
  3. Ex Vivo Model for Assessing the Vaginal Disposition of PrEP Antiretrovirals
    MARC MICHAEL BAUM; Fiscal Year: 2013
    ....
  4. Differential HIV infection and tenofovir activity in pre and postmenopausal women
    Gustavo F Doncel; Fiscal Year: 2013
    ....
  5. Optimizing Antiretroviral-Based Prevention by Enhancing PrEP Adherence in MSM
    Kenneth H Mayer; Fiscal Year: 2013
    ..The proposed study will allow for the development of an optimal AC prevention package, including combined biomedical and behavioral approaches to HIV prevention. ..
  6. Single and multi-component biguanide-based microbicides
    Mohamed Labib; Fiscal Year: 2007
    ....
  7. Single and multi-component biguanide-based microbicides
    Mohamed Labib; Fiscal Year: 2006
    ....
  8. Non-Toxic Gel to Treat Vulvovaginal Candidiasis
    Charles Gauntt; Fiscal Year: 2006
    ..Annual costs for treating WC in the U.S. are estimated at $1.8 billion. [unreadable] [unreadable]..
  9. Preclinical Pharmacology and Toxicology Studies
    Michael Pawlita; Fiscal Year: 2013
    ..This project is to provide pre-clinical safety on a new formulation of diindolylymethane (DIM). The project will be testing the vaginal cream in rabbits and guinea pigs for safety. ..
  10. Multitargeted Microbicide Combinations to Block HIV
    Betsy Herold; Fiscal Year: 2007
    ..The proposed comprehensive preclinical evaluation of combinations and clinical evaluation of PRO 2000 will lay the groundwork for future clinical trials with optimal combinations. ..
  11. Multitargeted Microbicide Combinations to Block HIV
    Betsy Herold; Fiscal Year: 2006
    ..The proposed comprehensive preclinical evaluation of combinations and clinical evaluation of PRO 2000 will lay the groundwork for future clinical trials with optimal combinations. ..
  12. VAGINAL BIOPROTECTION BY CONTROLLED ACIDIFICATION
    ES NUWAYSER; Fiscal Year: 2005
    ....
  13. DEVELOPMENT AND TESTING OF ACIDIC BUFFERS
    Richard Cone; Fiscal Year: 1999
    ..The feasability of adding lactobacilli to both formulations will be explored. ..
  14. TREATMENT FOR GBS COLONIZATION IN PREGNANT WOMEN
    Bakul Bhatt; Fiscal Year: 2001
    ..proposed commercial application: not available ..
  15. Enhancing HIV Prevention Among High-Risk HIV+ Men
    Kenneth Mayer; Fiscal Year: 2007
    ..Participants will then be followed every three months for one year, integrating PCM and/or prevention booster sessions to their HIV care visits. ..
  16. HIV PREVENTION TRIAL UNITS
    Kenneth Mayer; Fiscal Year: 2007
    ..We will continue our leadership work in community education and the engagement of diverse communities in HIV prevention initiatives. ( ..
  17. A Contextual Model of Microbicide Acceptability
    Kathleen Morrow; Fiscal Year: 2005
    ..abstract_text> ..
  18. Estrogen & Progesterone Effects on Orthostatic Tolerance
    NINA STACHENFELD; Fiscal Year: 2010
    ..We also expect that the data in these studies will provide a basis to study the impact of sex hormones on diseases related to compromised peripheral circulation, such as hypertension, Raynaud's phenomenon and diabetes ..
  19. LYME DISEASE--HOST PARASITE INTERACTIONS
    STEPHEN MALAWISTA; Fiscal Year: 2003
    ..These studies may provide the technical and conceptual basis for improvements in diagnostic and prognostic aspects of inflammatory diseases. ..
  20. IMPACT OF SCHOOL QUALITY ON ADOLESCENTS
    Barbara Mensch; Fiscal Year: 2001
    ....
  21. Assessing & Improving the Measurement of Sexual Behavior
    Barbara Mensch; Fiscal Year: 2008
    ..abstract_text> ..
  22. Acupuncture/Reproductive Hormones/Ovulation/Polycystic
    Lisa Pastore; Fiscal Year: 2007
    ..g., normal insulin, smaller body mass index) are more responsive to acupuncture therapy. We will also compare enrollment strategies for population-based recruitment of women into an acupuncture clinical trial. [unreadable] [unreadable]..
  23. Fragile X Premutations Among Women Diagnosed with Diminished Ovarian Reserve
    Lisa Pastore; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  24. Linking Biophysical Functions of Microbicides to User Perception & Acceptability
    Kathleen Morrow; Fiscal Year: 2007
    ..In sum, this work will contribute methodology leading to rational design of microbicide formulations that co-optimize vaginal distribution and retention with user acceptability. ..
  25. VULVODYNIA PREVALENCE AND EFFICACY OF 4 INTERVENTIONS
    Gloria Bachmann; Fiscal Year: 2004
    ..Our ultimate goal is to share findings from this and related research with the broadest cross-spectrum of women that we can. ..
  26. HARLEM AIDS TREATMENT GROUP-'CPCRA'
    Wafaa El Sadr; Fiscal Year: 2006
    ..They also are committed to the conduct of large long-term studies as a means of answering key questions in HIV management that cannot be answered through shorter trials. ..
  27. TUBERCULOSIS ADHERENCE PARTNERSHIP ALLIANCE STUDY
    Wafaa El Sadr; Fiscal Year: 2004
    ..abstract_text> ..
  28. SEX HORMONES AND BODY FLUID REGULATION
    NINA STACHENFELD; Fiscal Year: 2003
    ....
  29. HIV PREVENTION TRIAL UNIT (PRIDE NYC PROGRAM)
    Wafaa El Sadr; Fiscal Year: 2006
    ..abstract_text> ..
  30. Resolution of Gouty Inflammation
    STEPHEN MALAWISTA; Fiscal Year: 2008
    ..We suggest further that this reprogramming of lipid mediators may explain in part the action of therapeutic agents such as colchicine, and could lead to better treatment for this condition. [unreadable] [unreadable] [unreadable]..