phenol

Summary

Summary: An antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. It has been used to disinfect skin and to relieve itching. (From Martindale, The Extra Pharmacopoeia, 30th ed, p801)

Top Publications

  1. ncbi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    P Chomczynski
    Anal Biochem 162:156-9. 1987
  2. ncbi The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on
    Piotr Chomczynski
    Molecular Research Center, 2600 Clifton Avenue, Cincinnati, Ohio 45221, USA
    Nat Protoc 1:581-5. 2006
  3. ncbi Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries
    N Hobara
    Department of Clinical Pharmaceutical Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1 1 1 Tsushima naka, Okayama 700 8530, Japan
    Neuroscience 150:730-41. 2007
  4. pmc Population dynamics of phenol-degrading bacteria in activated sludge determined by gyrB-targeted quantitative PCR
    K Watanabe
    Corporate Research and Development Laboratories, Tonen Corporation, Saitama, Japan
    Appl Environ Microbiol 64:1203-9. 1998
  5. ncbi Grouping of phenol hydroxylase and catechol 2,3-dioxygenase genes among phenol- and p-cresol-degrading Pseudomonas species and biotypes
    Merike Merimaa
    Department of Genetics, Institute of Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu, Estonia
    Arch Microbiol 186:287-96. 2006
  6. ncbi Antioxidant activity, phenol and flavonoid contents of 13 citrus species peels and tissues
    Kamran Ghasemi
    Department of Horticulture, Faculty of Agriculture, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran
    Pak J Pharm Sci 22:277-81. 2009
  7. pmc Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles
    Bas G J Surewaard
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS Pathog 8:e1002606. 2012
  8. ncbi Bioenergetic strategy of microalgae for the biodegradation of phenolic compounds: exogenously supplied energy and carbon sources adjust the level of biodegradation
    Aikaterini Papazi
    Department of Biology, University of Crete, Heraklion, Crete, Greece
    J Biotechnol 129:706-16. 2007
  9. doi Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells
    Nobuhiro Ikezawa
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo, Kyoto, Japan
    J Biol Chem 283:8810-21. 2008
  10. ncbi Evaluation of the antioxidant properties of litchi fruit phenolics in relation to pericarp browning prevention
    Xuewu Duan
    South China Botanical Garden, The Chinese Academy of Sciences, Guangzhou Leyiju 510650, PR China
    Molecules 12:759-71. 2007

Detail Information

Publications333 found, 100 shown here

  1. ncbi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    P Chomczynski
    Anal Biochem 162:156-9. 1987
    A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described. The method provides a pure preparation of undegraded RNA in high yield and can be completed within 4 h...
  2. ncbi The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on
    Piotr Chomczynski
    Molecular Research Center, 2600 Clifton Avenue, Cincinnati, Ohio 45221, USA
    Nat Protoc 1:581-5. 2006
    ..is separated from DNA after extraction with an acidic solution containing guanidinium thiocyanate, sodium acetate, phenol and chloroform, followed by centrifugation...
  3. ncbi Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries
    N Hobara
    Department of Clinical Pharmaceutical Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1 1 1 Tsushima naka, Okayama 700 8530, Japan
    Neuroscience 150:730-41. 2007
    ..II (Ang II) type 2 receptors (AT2 receptors) in restoration of perivascular nerve innervation injured by topical phenol treatment...
  4. pmc Population dynamics of phenol-degrading bacteria in activated sludge determined by gyrB-targeted quantitative PCR
    K Watanabe
    Corporate Research and Development Laboratories, Tonen Corporation, Saitama, Japan
    Appl Environ Microbiol 64:1203-9. 1998
    ..The adequacy of the method was examined by analyzing the population dynamics of two phenol-degrading bacteria, Pseudomonas putida BH and Comamonas sp...
  5. ncbi Grouping of phenol hydroxylase and catechol 2,3-dioxygenase genes among phenol- and p-cresol-degrading Pseudomonas species and biotypes
    Merike Merimaa
    Department of Genetics, Institute of Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu, Estonia
    Arch Microbiol 186:287-96. 2006
    b>Phenol- and p-cresol-degrading pseudomonads isolated from phenol-polluted water were analysed by the sequences of a large subunit of multicomponent phenol hydroxylase (LmPH) and catechol 2,3-dioxygenase (C23O), as well as according to the ..
  6. ncbi Antioxidant activity, phenol and flavonoid contents of 13 citrus species peels and tissues
    Kamran Ghasemi
    Department of Horticulture, Faculty of Agriculture, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran
    Pak J Pharm Sci 22:277-81. 2009
    ..3 to 31.1 mg quercetin equivalent/g of extract. There were no correlation between the total phenolic and/or flavonoids contents and antioxidant activity in tissues and/or peels...
  7. pmc Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles
    Bas G J Surewaard
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS Pathog 8:e1002606. 2012
    Staphylococcus aureus virulence has been associated with the production of phenol soluble modulins (PSM). PSM are known to activate, attract and lyse neutrophils...
  8. ncbi Bioenergetic strategy of microalgae for the biodegradation of phenolic compounds: exogenously supplied energy and carbon sources adjust the level of biodegradation
    Aikaterini Papazi
    Department of Biology, University of Crete, Heraklion, Crete, Greece
    J Biotechnol 129:706-16. 2007
    ..of microalgae incubated with phenols, it can be assumed that, at least in low concentrations, phenol have no toxic effects on the cultures and can be used as alternative carbon source in them...
  9. doi Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells
    Nobuhiro Ikezawa
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo, Kyoto, Japan
    J Biol Chem 283:8810-21. 2008
    ..several unique P450 reactions have been reported, such as methylenedioxy bridge formation, intramolecular C-C phenol-coupling and intermolecular C-O phenol-coupling reactions...
  10. ncbi Evaluation of the antioxidant properties of litchi fruit phenolics in relation to pericarp browning prevention
    Xuewu Duan
    South China Botanical Garden, The Chinese Academy of Sciences, Guangzhou Leyiju 510650, PR China
    Molecules 12:759-71. 2007
    ..These results suggest that litchi pericarp tissue phenolics could be beneficial in scavenging free radicals, maintaining membrane integrity and, thereby inhibiting pericarp browning of litchi fruit...
  11. ncbi Phenol as an adjuvant for local control in the treatment of giant cell tumour of the bone
    H R Dürr
    Department of Orthopedics and Orthopedic Surgery, Ludwig Maximilians University Munich, Klinikum Grosshadern, Marchioninistr 15, Munich, D 81366, Germany
    Eur J Surg Oncol 25:610-8. 1999
    ..Due to the combined use of phenol and cementation in most studies, the effect of phenol alone is described in this study.
  12. ncbi Alternative surgical treatment for giant-cell reparative granuloma in the metacarpal, using phenol and ethanol adjuvant therapy
    Tatsuya Yoshida
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Hand Surg Am 32:887-92. 2007
    ..Adjuvant therapy usually is applied to reduce the recurrence of locally aggressive bone tumors. We report 2 cases of GCRG that were treated successfully with curettage, adjuvant phenol and ethanol, and autogenous bone grafting.
  13. ncbi Adaptation of Comamonas testosteroni TA441 to utilize phenol: organization and regulation of the genes involved in phenol degradation
    H Arai
    Laboratory of Microbiology, Institute of Physical and Chemical Research RIKEN, Saitama, Japan
    Microbiology 144:2895-903. 1998
    Comamonas testosteroni TA441 was not able to grow on phenol as a sole carbon and energy source, but it gained the ability to utilize phenol after a 2-3-week incubation in a medium containing phenol...
  14. doi Phenol-oxidizing laccases from the termite gut
    M R Coy
    Department of Entomology and Nematology, University of Florida, Gainesville, FL 32611, USA
    Insect Biochem Mol Biol 40:723-32. 2010
    ..These findings contribute to a better understanding of termite digestion and gut physiology, and will assist future translational studies that examine the contributions of individual termite enzymes in lignocellulose digestion...
  15. pmc Ligand escape pathways and (un)binding free energy calculations for the hexameric insulin-phenol complex
    Harish Vashisth
    Department of Chemical and Biological Engineering, Drexel University, Philadelphia, Pennsylvania, USA
    Biophys J 95:4193-204. 2008
    ..b>Phenol dissociation is rapid on hexamer dissolution timescales, and phenol unbinding upon dilution is likely the first ..
  16. pmc Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry
    David J Gonzalez
    Department of Pediatrics, University of California at San Diego, La Jolla, California 92093, USA
    J Biol Chem 287:13889-98. 2012
    ..aureus (CA-MRSA) with homology to the phenol-soluble modulins (PSMs) from Staphylococcus epidermidis...
  17. doi Cell-based biosensor for measurement of phenol and nitrophenols toxicity
    Chang Liu
    State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
    Talanta 84:766-70. 2011
    A cost-effective whole cell biosensor based on electrochemical technique to detect toxicities of phenol and nitrophenols has been developed...
  18. pmc Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization
    Ingrid C McCall
    Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Toxicol Appl Pharmacol 241:61-70. 2009
    b>Phenol contamination of soil and water has raised concerns among people living near phenol-producing factories and hazardous waste sites containing the chemical...
  19. ncbi The thermophilic archaeon Sulfolobus solfataricus is able to grow on phenol
    Viviana Izzo
    Dipartimento di Biologia Strutturale e Funzionale, Universita di Napoli Federico II, Complesso Universitario di Monte S Angelo, Via Cinthia, 80126 Naples, Italy
    Res Microbiol 156:677-89. 2005
    ..In this paper we report that S. solfataricus can efficiently grow on phenol as the sole source of carbon and energy...
  20. ncbi Differential gene expression in response to phenol and catechol reveals different metabolic activities for the degradation of aromatic compounds in Bacillus subtilis
    Le Thi Tam
    Institut fur Mikrobiologie, Ernst Moritz Arndt Universitat Greifswald, F L Jahn Strasse 15, D 17487 Greifswald, Germany
    Environ Microbiol 8:1408-27. 2006
    ..We report here the global response of Bacillus subtilis 168 to phenol and catechol using proteome and transcriptome analyses...
  21. ncbi Kinetics of phenol and chlorophenol utilization by Acinetobacter species
    Oliver J Hao
    Department of Civil and Environmental Engineering, University of Maryland, College Park 20742, USA
    Chemosphere 46:797-807. 2002
    ..The present study investigated the degradation kinetics of self-inhibitory growth (phenol) and nongrowth (4-chlorophenol, 4-CP) substrates, present individually and in combination...
  22. ncbi Effect of activated carbons modification on porosity, surface structure and phenol adsorption
    G G Stavropoulos
    Chemical Engineering Department, Aristotle University of Thessaloniki, TEI campus, P O Box 1520, 54006 Thessaloniki, Greece
    J Hazard Mater 151:414-21. 2008
    ..Urea treated samples with a basic character and high nitrogen content presented the highest phenol uptake capacity; nitric acid treated carbons and oxygen gasified samples presented an acidic surface functionality ..
  23. ncbi Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity
    Shaohua Ye
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Am J Hypertens 15:717-24. 2002
    Intrarenal injection of phenol in rats causes a persistent elevation in blood pressure (BP) and in norepinephrine (NE) secretion from the posterior hypothalamus (PH), and downregulation of neuronal nitric oxide synthase (nNOS) and ..
  24. ncbi Oxidative stress mediates the stimulation of sympathetic nerve activity in the phenol renal injury model of hypertension
    Shaohua Ye
    Division of Nephrology, Hypertension Center, Keck School of Medicine, University of Southern California, 1200 North State St, Los Angeles, CA 90033, USA
    Hypertension 48:309-15. 2006
    Renal injury caused by the injection of phenol in the lower pole of one kidney increases blood pressure (BP), norepinephrine secretion from the posterior hypothalamic nuclei (PH), and renal sympathetic nerve activity in the rat...
  25. ncbi The cyo operon of Pseudomonas putida is involved in carbon catabolite repression of phenol degradation
    L Petruschka
    , , , Greifswald, Germany
    Mol Genet Genomics 266:199-206. 2001
    ..of the promoterless genes aacC1 (conferring gentamycin resistance) and lacZ fused to the catabolic promoter of the phenol degradation genes was used to identify and analyse mutants of Pseudomonas putida with altered carbon catabolite ..
  26. ncbi Local recurrence of giant cell tumor of bone after intralesional treatment with and without adjuvant therapy
    Wolfgang T Becker
    Orthopädische Klinik Volmarstein, Universitat Witten Herdecke, Wetter, Germany
    J Bone Joint Surg Am 90:1060-7. 2008
    ..The purpose of this study was to analyze the rates of recurrence following different types of treatment as well as the influence of various factors of tumor presentation on those rates...
  27. pmc Analysis of current and alternative phenol based RNA extraction methodologies for cyanobacteria
    Fernando Lopes Pinto
    Department of Photochemistry and Molecular Science, The Angstrom Laboratories, Uppsala University, Box 523, SE 75120, Uppsala, Sweden
    BMC Mol Biol 10:79. 2009
    ..Therefore, we used the NHM5 strain of Nostoc punctiforme ATCC 29133 to compare and improve existing phenol based chemistry and procedures for RNA extraction.
  28. ncbi Internal mass transfer effect on biodegradation of phenol by Ca-alginate immobilized Ralstonia eutropha
    Arzu Y Dursun
    Department of Environmental Engineering, Firat University, 23100 Elazig, Turkey
    J Hazard Mater 126:105-11. 2005
    b>Phenol biodegradation by free and Ca-alginate immobilized Ralstonia eutropha was performed in batch system...
  29. ncbi Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 revealed by quantitative proteomics
    Pedro M Santos
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisboa, Portugal
    OMICS 11:233-51. 2007
    Quantitative proteomics was used to gain insights into the global adaptive response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 when an alternative carbon source (pyruvate or succinate) is present...
  30. ncbi Regioselective nitration of phenol induced by catalytic antibodies
    Remy Ricoux
    Laboratoire de Chimie Bioorganique et Bioinorganique, FRE 2127 CNRS, Institut de Chimie Moléculaire d Orsay, Bat 420, Universite de Paris Sud XI, 91405, Orsay Cedex, France
    J Protein Chem 21:473-7. 2002
    ..This paper shows that those complexes also catalyzed efficiently the nitration of phenol into 2- and 4-nitrophenol by NO2- in the presence of H2O2...
  31. ncbi Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase
    Kohtaro Kirimura
    Department of Applied Chemistry, Faculty of Science and Engineering, Waseda University, 3 4 1 Ohkubo, Shinjuku ku 169 8555, Tokyo, Japan
    Biochem Biophys Res Commun 394:279-84. 2010
    Salicylic acid decarboxylase (Sdc) can produce salicylic acid from phenol; it was found in the yeast Trichosporon moniliiforme WU-0401 and was for the first time enzymatically characterized, with the sdc gene heterologously expressed...
  32. doi Microorganisms involved in anaerobic phenol degradation in the treatment of synthetic coke-oven wastewater detected by RNA stable-isotope probing
    Kazuo Sueoka
    Institute of Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan
    FEMS Microbiol Lett 291:169-74. 2009
    An RNA-based stable-isotope probing method was used to identify anaerobic phenol-assimilating bacteria present in activated sludge and used to treat synthetic coke-oven wastewater...
  33. ncbi Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure
    Y Panahi
    Department of Chemical Injury, Baqyatallah Hospital, Tehran, Iran
    Singapore Med J 48:392-5. 2007
    ..The current study evaluated the efficacy of a combination of one percent phenol and one percent menthol in the control of pruritus in these affected patients.
  34. pmc The alkene monooxygenase from Xanthobacter strain Py2 is closely related to aromatic monooxygenases and catalyzes aromatic monohydroxylation of benzene, toluene, and phenol
    N Y Zhou
    Department of Biochemistry, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom
    Appl Environ Microbiol 65:1589-95. 1999
    ..Detailed comparison of XamoA with the oxygenase alpha-subunits from aromatic monooxygenases, phenol hydroxylases, methane monooxygenase, and the alkene monooxygenase from Rhodococcus rhodochrous B276 showed that, ..
  35. ncbi Rhodococcus phenolicus sp. nov., a novel bioprocessor isolated actinomycete with the ability to degrade chlorobenzene, dichlorobenzene and phenol as sole carbon sources
    Marc Rehfuss
    Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Syst Appl Microbiol 28:695-701. 2005
    The aerobic degradation of phenol, chlorobenzene and dichlorobenzene as a sole carbon source has been observed in bacterial Gram-positive strain G2PT isolated from a wastewater bioprocessor...
  36. pmc Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600
    V Shingler
    Unit for Applied Cell and Molecular Biology, University of Umea, Sweden
    J Bacteriol 174:711-24. 1992
    ..Pseudomonas sp. strain CF600 grows efficiently on phenol, cresols, and 3,4-dimethylphenol via a plasmid-encoded multicomponent phenol hydroxylase and a subsequent meta-..
  37. ncbi Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds
    Andrew M Jenner
    Biochemistry Department, Faculty of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597
    Free Radic Biol Med 38:763-72. 2005
    ..This study is the first to measure the range of aromatic compounds in human fecal water and demonstrates that phenolic acid concentrations are high. The biological effects of phenolics may play an important role in colon function...
  38. pmc Phenylphosphate carboxylase: a new C-C lyase involved in anaerobic phenol metabolism in Thauera aromatica
    Karola Schühle
    Mikrobiologie, Institut Biologie II, Universitat Freiburg, Germany
    J Bacteriol 186:4556-67. 2004
    The anaerobic metabolism of phenol in the beta-proteobacterium Thauera aromatica proceeds via carboxylation to 4-hydroxybenzoate and is initiated by the ATP-dependent conversion of phenol to phenylphosphate...
  39. ncbi Comparison of different advanced oxidation processes for phenol degradation
    Santiago Esplugas
    Departamento de Ingenieria Química y Metalurgia de la Universidad de Barcelona, Spain
    Water Res 36:1034-42. 2002
    ..Processes (O3, O3/H2O2, UV, UV/O3, UV/H2O2, O3/UV/H2O2, Fe2+ /H2O2 and photocatalysis) for degradation of phenol in aqueous solution have been studied in earlier works...
  40. ncbi Response of Pseudomonas putida KT2440 to phenol at the level of membrane proteome
    Catarina Roma-Rodrigues
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Lisboa, Portugal
    J Proteomics 73:1461-78. 2010
    ..led to the extension and refinement of our current model for the global response of Pseudomonas putida KT2440 to phenol by getting insights into the adaptive response mechanisms involving the membrane proteome...
  41. doi Study of phenol biodegradation using Bacillus amyloliquefaciens strain WJDB-1 immobilized in alginate-chitosan-alginate (ACA) microcapsules by electrochemical method
    Daban Lu
    Department of Chemistry, Lanzhou University, Lanzhou, 730000, People s Republic of China
    Biodegradation 23:209-19. 2012
    An aerobic microorganism with an ability to utilize phenol as sole carbon and energy source was isolated from phenol-contaminated wastewater samples...
  42. ncbi Evolution of toxicity upon wet catalytic oxidation of phenol
    A Santos
    Departamento de Ingenieria Quimica, Facultad de Ciences Químicas, Universidad Complutense de Madrid, Cuidad Universitaria s n 28040, Madrid, Spain
    Environ Sci Technol 38:133-8. 2004
    This work reports on the evolution of the toxicity of phenol-containing simulated wastewater upon catalytic wet oxidation with a commercial copper-based catalyst (Engelhard Cu-0203T)...
  43. ncbi Bacterial degradation of airborne phenol in the phyllosphere
    Amarjyoti Sandhu
    Department of Plant Pathology and Interdepartmental Microbiology Program, Iowa State University, Ames, IA 50011 3211, USA
    Environ Microbiol 9:383-92. 2007
    ..Here, we examined bacterial acquisition and degradation of phenol on leaves by an introduced phenol degrader and by natural phyllosphere communities...
  44. doi Integrated photocatalytic-biological reactor for accelerated phenol mineralization
    Yongming Zhang
    Department of Environmental Engineering, College of Life and Environmental Science, Shanghai Normal University, Shanghai, 200234, People s Republic of China
    Appl Microbiol Biotechnol 86:1977-85. 2010
    An integrated photocatalytic-biological reactor (IPBR) was developed for accelerated phenol degradation and mineralization...
  45. doi Enhancement of phenol degradation by soil bioaugmentation with Pseudomonas sp. JS150
    A Mrozik
    Department of Biochemistry, University of Silesia, Jagiellonska 28, Katowice, Poland
    J Appl Microbiol 111:1357-70. 2011
    To test whether bioaugmentation with genetically modified Pseudomonas sp. JS150 strain could be used to enhance phenol degradation in contaminated soils.
  46. ncbi Influence of phenol on the biodegradation of pyridine by freely suspended and immobilized Pseudomonas putida MK1
    M K Kim
    Environmental and Molecular Microbiology Laboratory, Department of Biological Sciences, Korea Advanced Institute of Science and Technology KAIST, Daejeon, Korea
    Lett Appl Microbiol 42:495-500. 2006
    To study the effect of co-contaminants (phenol) on the biodegradation of pyridine by freely suspended and calcium alginate immobilized bacteria.
  47. ncbi Antioxidant activities of estrogens against aqueous and lipophilic radicals; differences between phenol and catechol estrogens
    M B Ruiz-Larrea
    Departamento de Fisiologia, Facultad de Medicina, Universidad del Pais Vasco UPV EHU, Bilbao, Spain
    Chem Phys Lipids 105:179-88. 2000
    ..The antioxidant activity of an estrogen depends not only on the hydrophilic or lipophilic nature of the scavenged radical, but also on the phenol and catechol structures of the estrogen compound.
  48. ncbi Sonographically guided phenol injection in painful stump neuroma
    Hannes Gruber
    Department of Radiodiagnostics, University Hospital Innsbruck, Anichstrasse 35, Innsbruck 6020, Austria
    AJR Am J Roentgenol 182:952-4. 2004
  49. doi Remediation of phenol-contaminated soil by a bacterial consortium and Acinetobacter calcoaceticus isolated from an industrial wastewater treatment plant
    S M Cordova-Rosa
    Universidade do Vale do Itajai, Centro de Ciências Tecnológicas da Terra e do Mar, 88302 202, Itajai, SC, Brazil
    J Hazard Mater 164:61-6. 2009
    Time-course performance of a phenol-degrading indigenous bacterial consortium, and of Acinetobacter calcoaceticus var. anitratus, isolated from an industrial coal wastewater treatment plant was evaluated...
  50. doi Automatic biodetector of water toxicity (ABTOW) as a tool for examination of phenol and cyanide contaminated water
    Andrzej Woznica
    Department of Biochemistry, Faculty of Biology and Environmental Protection, University of Silesia, 40 032 Katowice, Poland
    Chemosphere 81:767-72. 2010
    ..The dynamics of ABTOW response is studied in details for phenol and cyanide as model toxins. These data indicate that the sensitivity was 3.5 μM for phenol and 0...
  51. doi Adsorption and recognizing ability of molecular imprinted polymer MIP-PEI/SiO(2) towards phenol
    Fuqiang An
    Department of Chemical Engineering, North University of China, Taiyuan, PR China
    J Hazard Mater 157:286-92. 2008
    ..imprinting was carried out towards the macromolecule PEI grafted on the surface of silica particles using phenol as a template and diepoxyalkyl (669) as a crosslinking agent...
  52. ncbi Combined biological and photocatalytic treatment for the mineralization of phenol in water
    Dhanus Suryaman
    Department of Chemical and Biochemical Engineering, Faculty of Engineering, Toyama University, 3190 Gofuku, Toyama 930 8555, Japan
    Chemosphere 65:2502-6. 2006
    b>Phenol is degraded by biological treatment, however mineralization requires long time...
  53. ncbi Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp strain ST-550 in a water-organic solvent two-phase system
    N Doukyu
    Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8501, Japan
    Appl Microbiol Biotechnol 60:720-5. 2003
    ..One of the proteins showed a N-terminal amino acid sequence that was identical to that of the largest subunit of phenol hydroxylase (MopN) from A. calcoaceticus NCBI8250...
  54. doi Artificial neural network modeling in competitive adsorption of phenol and resorcinol from water environment using some carbonaceous adsorbents
    R M Aghav
    Civil Engineering Department, Jadavpur University, Kolkata 700 032, West Bengal, India
    J Hazard Mater 188:67-77. 2011
    ..the application of artificial neural network (ANN) for prediction of performances in competitive adsorption of phenol and resorcinol from aqueous solution by conventional and low cost carbonaceous adsorbent materials, such as ..
  55. pmc Group-specific monitoring of phenol hydroxylase genes for a functional assessment of phenol-stimulated trichloroethylene bioremediation
    H Futamata
    Marine Biotechnology Institute, Kamaishi Laboratories, Heita, Kamaishi City, Iwate 026-0001, Japan
    Appl Environ Microbiol 67:4671-7. 2001
    The sequences of the largest subunit of bacterial multicomponent phenol hydroxylases (LmPHs) were compared...
  56. ncbi Photocatalytic degradation of phenol
    Feryal Akbal
    Ondokuz Mayis University, Faculty of Engineering, Environmental Engineering Department, Kurupelit Samsun, Turkey
    Environ Monit Assess 83:295-302. 2003
    In this study photocatalytic degradation of phenol in the presence of UV irradiated TiO2 catalyst and H2O2 was investigated. Effects of TiO2 and H2O2 concentrations and pH on photocatalytic degradation were examined...
  57. ncbi Phenol-induced in vivo oxidative stress in skin: evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion
    A R Murray
    Department of Physiology and Pharmacology, West Virginia University, Morgantown 26506, USA
    Chem Res Toxicol 20:1769-77. 2007
    A variety of phenolic compounds are utilized in industry (e.g., for the production of phenol (PhOH)-formaldehyde resins, paints and lacquers, cosmetics, and pharmaceuticals)...
  58. ncbi A luxCDABE-based bioluminescent bioreporter for the detection of phenol
    D Abd-El-Haleem
    The Center for Environmental Biotechnology, The University of Tennessee, Knoxville, TN 37996, USA
    J Ind Microbiol Biotechnol 29:233-7. 2002
    A bioluminescent reporter strain, Acinetobacter sp. DF4-8, was constructed for the detection of phenol by inserting a mopR-like promoter upstream of the Vibrio fischeri bioluminescent luxCDABE gene cassette in a modified mini-Tn5 ..
  59. ncbi Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin
    N A Monteiro-Riviere
    Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
    Toxicol Ind Health 17:95-104. 2001
    Pure phenol is colorless and used in the manufacture of phenolic resins, plastics, explosives, fertilizers, paints, rubber, textiles, adhesives, pharmaceuticals, paper, soap, and wood preservatives...
  60. doi Effect of biosurfactants on laccase production and phenol biodegradation in solid-state fermentation
    Mei Fang Zhou
    College of Environmental Science and Engineering, Hunan University, Changsha, People s Republic of China
    Appl Biochem Biotechnol 164:103-14. 2011
    ..of two biosurfactants, tea saponin (TS) and rhamnolipid (RL), on the production of laccase and the degradation of phenol by P...
  61. doi Phenol biosensor based on hydrogel microarrays entrapping tyrosinase and quantum dots
    Eunji Jang
    Department of Chemical and Biomolecular Engineering, Yonsei University, 134 Sinchon dong, Seodaemoon Gu, Seoul, 120 749, Republic of Korea
    Analyst 135:2871-8. 2010
    This paper describes the use of microarray-based biosensor system for the determination of phenol. Microarrays based on poly(ethylene glycol)(PEG) hydrogel were prepared by photopatterning of a solution containing PEG diacrylate (PEG-DA), ..
  62. ncbi Prolonged elimination half-life of phenol after dermal exposure
    Y Bentur
    Rambam Medical Center, Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    J Toxicol Clin Toxicol 36:707-11. 1998
    b>Phenol is a general protoplastic poison which has been in use in medicine and industry for decades. It is readily absorbed through the skin causing both local and systemic toxicity.
  63. ncbi Comparison of phenol and sodium hydroxide chemical matricectomies for the treatment of ingrowing toenails
    Seher Bostanci
    Department of Dermatology, Ankara University, Medical School, Ankara, Turkey
    Dermatol Surg 33:680-5. 2007
    Chemical matricectomy is performed mainly by two agents: phenol and sodium hydroxide. Both agents have excellent cure rates, but there are no data about the comparison of postoperative healing periods...
  64. ncbi Enrichment and cultivation of pelagic bacteria from a humic lake using phenol and humic matter additions
    Kristine Michelle L Hutalle-Schmelzer
    Department of Limnology of Stratified Lakes, Leibniz Institute of Freshwater Ecology and Inland Fisheries, Stechlin, Germany
    FEMS Microbiol Ecol 72:58-73. 2010
    ..To test how the availability of either pure phenol or natural humic matter (HM) selects for specific pelagic bacteria phylotypes from a humic lake (Lake Grosse ..
  65. doi Batch adsorption of phenol onto physiochemical-activated coconut shell
    Azam T Mohd Din
    School of Chemical Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Penang, Malaysia
    J Hazard Mater 161:1522-9. 2009
    The liquid-phase adsorption of phenol onto coconut shell-based activated carbon, CS850A was investigated for its equilibrium studies and kinetic modeling...
  66. ncbi The effect of phenol on ingrown toenail excision in children
    Saleem Islam
    CS Mott Children s Hospital, University of Michigan Health System, Ann Arbor, MI 48109, USA
    J Pediatr Surg 40:290-2. 2005
    ..The objective of this retrospective data review was to compare simple excision of the nail matrix with excision plus phenol (EPP) application in the treatment of ingrown toenails.
  67. ncbi Phenol degradation by immobilized cells of Arthrobacter citreus
    Chandrakant Karigar
    Biochemistry Division, Department of Chemistry, Central College Campus, Bangalore University, Bangalore, India
    Biodegradation 17:47-55. 2006
    An aerobic microorganism with an ability to utilize phenol as carbon and energy source was isolated from a hydrocarbon contamination site by employing selective enrichment culture technique...
  68. doi Oxidation of phenol by hydrogen peroxide catalyzed by metal-containing poly(amidoxime) grafted starch
    Hany El-Hamshary
    Petrochemical Research Chair, Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia
    Molecules 16:9900-11. 2011
    ..The produced metal-polyamidoxime polymer complexes were used as catalysts for the oxidation of phenol using H(2)O(2) as oxidizing agent...
  69. ncbi Minimizing postoperative drainage with 20% ferric chloride after chemical matricectomy with phenol
    A B Aksakal
    Gazi University, School of Medicine, Department of Dermatology, Ankara, Turkey
    Dermatol Surg 27:158-60. 2001
    b>Phenol used in partial matricectomy shows its effects by denaturing matrix proteins. This highly successful method has the major problem of oozing which can continue for 5-6 weeks.
  70. ncbi Toxicities of triclosan, phenol, and copper sulfate in activated sludge
    Rosalind A Neumegen
    Institute of Technology and Engineering, Massey University, Private Bag 11 222, Palmerston North, New Zealand
    Environ Toxicol 20:160-4. 2005
    ..of toxicants on the BOD degradation rate constant was used to quantitatively establish the toxicity of triclosan, phenol, and copper (II) against activated sludge microorganisms...
  71. doi The conversion of a phenol to an aniline occurs in the biochemical formation of the 1-(4-aminophenyl)-1-deoxy-D-ribitol moiety in methanopterin
    Robert H White
    Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 0308, USA
    Biochemistry 50:6041-52. 2011
    ..H. (1996) Biochemistry 35, 3447-3456]. This work represents the first biochemical example of the conversion of a phenol to an aniline.
  72. ncbi Gauze application of phenol for matrixectomy
    Ricardo Becerro de Bengoa Vallejo
    Universidad Complutense de Madrid, Madrid, Spain
    J Am Podiatr Med Assoc 98:418-21. 2008
    b>Phenol matrixectomy is commonly used to treat onychocryptosis. The podiatric medical community has been progressively improving the technique of phenol application to avoid cases of burns...
  73. doi The cytotoxic effect of phenol and ethanol on the chondrosarcoma-derived cell line OUMS-27: an in vitro experiment
    S H M Verdegaal
    Department of Orthopaedics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands
    J Bone Joint Surg Br 90:1528-32. 2008
    ..We investigated the potential for phenol to be used as an adjuvant...
  74. doi Silica-immobilized Methylobacterium sp. NP3 and Acinetobacter sp. PK1 degrade high concentrations of phenol
    P Khongkhaem
    Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
    Lett Appl Microbiol 52:448-55. 2011
    To immobilize Methylobacterium sp. NP3 and Acinetobacter sp. PK1 to silica and determine the ability of the immobilized bacteria to degrade high concentrations of phenol.
  75. doi Safety of phenol vapor inhalation during performance of chemical matrixectomy to treat ingrown toenails
    Marta Elena Losa Iglesias
    Health Sciences II Department, Universidad Rey Juan Carlos, Alcorcon, Madrid, Spain
    Dermatol Surg 34:1515-9. 2008
    b>Phenol is commonly used in chemical matrixectomies to treat ingrown toenails...
  76. ncbi Phenol cauterization for ganglions of the hand, wrist, and foot: a preliminary report
    S Park
    Division of Plastic Surgery, Shizuoka Children s Hospital, 860 Urushiyama, Shizuoka 420 8660, Japan
    Ann Plast Surg 48:582-5. 2002
    ..Their modification enables them to perform sclerotherapy safely and consistently, and they have treated 10 patients in this manner. The method is described and the cases are illustrated...
  77. doi [Comparison of phenol applications of different durations for the cauterization of the germinal matrix: an efficacy and safety study]
    Semih Tatlican
    Department of Dermatology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey
    Acta Orthop Traumatol Turc 43:298-302. 2009
    Partial nail avulsion with phenol matricectomy is one of the most widely performed procedures for the treatment of ingrowing nails. We compared phenol applications of different durations with respect to efficacy and safety.
  78. ncbi Characterization of phenol and trichloroethene degradation by the rhizobium Ralstonia taiwanensis
    Wen Ming Chen
    Department of Seafood Science, National Kaohsiung Marine University, Nan Tzu, Kaohsiung City 811, Hai Chuan Rd No 142, Taiwan
    Res Microbiol 155:672-80. 2004
    ..in southern Taiwan. Some strains of R. taiwanensis demonstrated the ability to grow on medium containing phenol as the sole carbon source, especially strain TJ86, which was able to survive and grow at phenol concentrations of ..
  79. ncbi Phenol burn
    Tsai Ming Lin
    Department of Plastic Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    Burns 32:517-21. 2006
  80. ncbi Performance of photocatalytic reactors using immobilized TiO2 film for the degradation of phenol and methylene blue dye present in water stream
    Chin Mei Ling
    School of Chemical Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Pulau Pinang, Malaysia
    Chemosphere 57:547-54. 2004
    ..1 H2O: 0.05 acetic acid (in molar ratio) gave excellent photocatalytic activity for degradation of phenol and methylene blue dye present in the water...
  81. ncbi Halomonas organivorans sp. nov., a moderate halophile able to degrade aromatic compounds
    Maria Teresa Garcia
    Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain
    Int J Syst Evol Microbiol 54:1723-8. 2004
    ..benzoic acid, p-hydroxybenzoic acid, cinnamic acid, salicylic acid, phenylacetic acid, phenylpropionic acid, phenol, p-coumaric acid, ferulic acid and p-aminosalicylic acid), and it could be useful for the decontamination of ..
  82. doi Improvement of an E. coli bioreporter for monitoring trace amounts of phenol by deletion of the inducible sigma54-dependent promoter
    Zixin Peng
    Key Laboratory of Crop Biotechnology, Biotechnology Research Institute, Ministry of Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China
    Biotechnol Lett 32:1265-70. 2010
    An Escherichia coli bioreporter harboring the phenol-inducible mphK promoter (P(mphK)) from Acinetobacter calcoaceticus PHEA-2 fused to a beta-galactosidase gene (lacZ) and the regulator gene (mopR) of A...
  83. ncbi DNA renaturation at the water-phenol interface
    A Goldar
    Groupe de Biophysique de l ADN, CEA Saclay, DBJC SBGM, 91191 Gif sur Yvette, France
    Eur Phys J E Soft Matter 14:211-39. 2004
    We study the renaturation of complementary single-stranded DNAs in a water-phenol two-phase system, with or without shaking...
  84. ncbi Quantitative structure-activity relationships in prooxidant cytotoxicity of polyphenols: role of potential of phenoxyl radical/phenol redox couple
    Ausra Nemeikaite-Ceniene
    Institute of Immunology of Vilnius University, Moletu pl 29, LT 08409 Vilnius, Lithuania
    Arch Biochem Biophys 441:182-90. 2005
    The aim of this work was to characterize the role of the potential of phenoxyl radical/phenol redox couple, E(7)(2), in the cytotoxicity of polyphenols...
  85. ncbi Phenol and catechol biodegradation by the haloalkaliphile Halomonas campisalis: influence of pH and salinity
    Victor A Alva
    Center for Multiphase Environmental Research, Consortium for Extremophile Research, Washington State University, Dana Hall, 118 Spokane Street, Pullman, Washington 99164 2710, USA
    Environ Sci Technol 37:4397-402. 2003
    ..compound biodegradation in saline and alkaline conditions, the effect of pH and salinity on the biodegradation of phenol as a model aromatic waste compound by the haloalkaliphilic bacterium Halomonas campisalis was examined...
  86. ncbi Binding of phenol and analogues to alanine complexes of tyrosine phenol-lyase from Citrobacter freundii: implications for the mechanisms of alpha,beta-elimination and alanine racemization
    H Chen
    Department of Chemistry, University of Georgia, Athens 30602
    Biochemistry 32:11591-9. 1993
    We have examined the interaction of Citrobacter freundii tyrosine phenol-lyase with both L- and D-alanine...
  87. ncbi Effects of phenol peeling on dermal endothelial cells
    Yuki Yamamoto
    J Dermatol Sci 35:158-61. 2004
  88. ncbi Analysis of catRABC operon for catechol degradation from phenol-degrading Rhodococcus erythropolis
    M Vesely
    Institute of Microbiology, Academy of Sciences of the Czech Republic, v v i, Videnska 1083, 14220, Prague 4, Czech Republic
    Appl Microbiol Biotechnol 76:159-68. 2007
    ..Measurements of catechol 1,2-dioxygenase activity showed that the expression of catA is induced by phenol but not by catechol or cis,cis-muconate...
  89. pmc Benzoate catabolite repression of the phenol degradation in Acinetobacter calcoaceticus PHEA-2
    Yuhua Zhan
    College of Biological Sciences, China Agriculture University, Beijing, PR China
    Curr Microbiol 59:368-73. 2009
    Acinetobacter calcoaceticus PHEA-2 exhibited a delayed utilization of phenol in the presence of benzoate. Benzoate supplementation completely inhibited phenol degradation in a benzoate 1,2-dioxygenase knockout mutant...
  90. doi The use of Trizol reagent (phenol/guanidine isothiocyanate) for producing high quality two-dimensional gel electrophoretograms (2-DE) of dinoflagellates
    Fred Wang Fat Lee
    The Proteomic Task Force, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong
    J Microbiol Methods 73:26-32. 2008
    ..In this study, we report the use of Trizol (a monophasic solution of phenol and guanidine isothiocyanate) for the extraction of proteins from dinoflagellate cells for 2-DE...
  91. doi Use of Folin-Ciocalteu phenol reagent and 3-methyl-2-benzothiazolinone hydrazine hydrochloride in the determination of oxcarbazepine in pharmaceuticals
    Muruganathan Gandhimathi
    Department of Pharmaceutical Analysis, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore, 641 044, India
    Acta Pharm 58:111-8. 2008
    ..methods are proposed for the assay of oxcarbazepine (OXC) in bulk and dosage forms using Folin-Ciocalteu phenol reagent (FCP) and 3-methyl-2-benzothiazolinone hydrazine hydrochloride (MBTH) as reagents...
  92. doi Isolation and characterization of hyper phenol tolerant Bacillus sp. from oil refinery and exploration sites
    Aditi Banerjee
    Center for Environment, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India
    J Hazard Mater 176:85-91. 2010
    ..19% among same genus similar sequences. At phenol concentration of 1000 mg/L, the optimum growth conditions for AKG1 were found to be 37 degrees C and pH 7...
  93. ncbi Growth of moderately halophilic bacteria isolated from sea water using phenol as the sole carbon source
    J A Munoz
    D S M Deretil Research Institute, 046 18 Almeria, Spain
    Folia Microbiol (Praha) 46:297-302. 2001
    Moderately halophilic bacteria utilizing phenol as the sole carbon source were isolated by selective enrichment from sea water. The isolate (Gram-negative motile rods) was identified as Deleya venusta...
  94. ncbi Kinetics of phenol biodegradation in high salt solutions
    Brent M Peyton
    Department of Chemical Engineering, Center for Multiphase Environmental Research, Washington State University, Pullman 99164 2710, USA
    Water Res 36:4811-20. 2002
    ..While halophilic degradation of phenol and other organics has been investigated, there exists a general absence of kinetic data in current literature to ..
  95. ncbi Characterization of Trametes versicolor laccase for the transformation of aqueous phenol
    Selvia Kurniawati
    Department of Civil Engineering and Applied Mechanics, McGill University, 817 Sherbrooke Street West Montreal, Quebec, Canada H3A 2K6
    Bioresour Technol 99:7825-34. 2008
    ..of its catalytic stability and its effectiveness as a biocatalyst under various reaction conditions when using phenol as a model substrate...
  96. doi Neurolytic phenol blockade of the obturator nerve for severe adductor spasticity
    T Akkaya
    Ministry of Health Diskapi Yildirim Beyazit Research and Educational Hospital, Clinic of I Anaesthesiology Reanimation and Pain Unit, Ankara, Turkey
    Acta Anaesthesiol Scand 54:79-85. 2010
    In this study, we present the 3-month follow-up results of a retrospective analysis of obturator nerve (ON) phenol neurolysis performed between 2000 and 2007 in patients with adductor spasticity.
  97. pmc An AraC/XylS family member at a high level in a hierarchy of regulators for phenol-metabolizing enzymes in Comamonas testosteroni R5
    Maki Teramoto
    Marine Biotechnology Institute, Kamaishi Laboratories, Kamaishi City, Iwate 026 0001, Japan
    J Bacteriol 184:3941-6. 2002
    Comamonas testosteroni strain R5 expresses a higher level of phenol-oxygenating activity than any other bacterial strain so far characterized...
  98. doi Identification and genetic characterization of phenol-degrading bacteria from leaf microbial communities
    Amarjyoti Sandhu
    Department of Plant Pathology and Interdepartmental Microbiology Program, Iowa State University, Ames, IA 50011, USA
    Microb Ecol 57:276-85. 2009
    Microbial communities on aerial plant leaves may contribute to the degradation of organic air pollutants such as phenol. Epiphytic bacteria capable of phenol degradation were isolated from the leaves of green ash trees grown at a site ..
  99. ncbi Approach to tetrodotoxin via the oxidative amidation of a phenol
    Brian A Mendelsohn
    Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada
    Org Lett 11:4736-9. 2009
    ..The stereoselective introduction of a beta-hydroxynitrile functionality on one of the double bonds of the emerging dienone is achieved through an intramolecular nitrile oxide cycloaddition-fragmentation sequence...
  100. pmc The impact of ColRS two-component system and TtgABC efflux pump on phenol tolerance of Pseudomonas putida becomes evident only in growing bacteria
    Marta Putrins
    Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia
    BMC Microbiol 10:110. 2010
    We have recently found that Pseudomonas putida deficient in ColRS two-component system is sensitive to phenol and displays a serious defect on solid glucose medium where subpopulation of bacteria lyses...
  101. ncbi Characterization of a high-affinity phenol hydroxylase from Comamonas testosteroni R5 by gene cloning, and expression in Pseudomonas aeruginosa PAO1c
    M Teramoto
    Marine Biotechnology Institute, Kamaishi Laboratories, Kamaishi City, Iwate, Japan
    Mol Gen Genet 262:552-8. 1999
    Comamonas testosteroni strain R5 is a phenol-degrading bacterium which expresses a phenol-oxygenating activity that is characterized by low Ks (the apparent half-saturation constant in Haldane's equation) and low K(SI) (the apparent ..

Research Grants89

  1. APPLICATION OF CRYSTALLOGRAPHIC TECHNIQUES
    JENNY GLUSKER; Fiscal Year: 2002
    ..Some ab initio molecular orbital studies of reaction pathways in the metabolism of benzene and phenol will also be carried out...
  2. MECHANISMS OF PYRIDOXAL-5'-PHOSPHATE DEPENDENT ENZYMES
    Robert Phillips; Fiscal Year: 2004
    ..These enzymes include tryptophan indole-lyase, tyrosine phenol-lyase, tryptophan synthase, bacterial and human kynureninases, and aspartate beta-decarboxylase...
  3. Quercetin and Innate Immune Responses in COPD
    Umadevi Sajjan; Fiscal Year: 2009
    ..John's Wort, both popular health supplements. Flavonoids share a common chemical structure consisting of two phenol rings linked through three carbons...
  4. Quercetin and Innate Immune Responses in COPD
    UMADEVI SIVANAPPA SAJJAN; Fiscal Year: 2010
    ..John's Wort, both popular health supplements. Flavonoids share a common chemical structure consisting of two phenol rings linked through three carbons...
  5. Tyrosinase Model Complexes using Imidazole Ligands
    JOHN BRANNON GARY; Fiscal Year: 2012
    ..a substrate-binding induced rearrangement to an isomeric bis-m-oxo-dicopper(III) intermediate (O) that performs phenol oxidation with electronic and kinetic isotope parameters consistent with enzymatic values...
  6. Nonheme Diiron Centers/Biological Oxidation Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2006
    ..proteins, and of complexes between them, from three bacterial systems, sMMO, toluene/o-xylene monooxygenase, and phenol hydroxylase, will be investigated by X-ray crystallography and NMR spectroscopy...
  7. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2007
    ..proteins, and of complexes between them, from three bacterial systems, sMMO, toluene/o-xylene monooxygenase, and phenol hydroxylase, will be investigated by X-ray crystallography and NMR spectroscopy...
  8. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..proteins, and of complexes between them, from three bacterial systems, sMMO, toluene/o-xylene monooxygenase, and phenol hydroxylase, will be investigated by X-ray crystallography and NMR spectroscopy...
  9. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..proteins, and of complexes between them, from three bacterial systems, sMMO, toluene/o-xylene monooxygenase, and phenol hydroxylase, will be investigated by X-ray crystallography and NMR spectroscopy...
  10. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2007
    ..proteins, and of complexes between them, from three bacterial systems, sMMO, toluene/o-xylene monooxygenase, and phenol hydroxylase,will be investigated by X-ray crystallography and NMR spectroscopy...
  11. HEPATOBILIARY DISPOSITION IN TOXICOLOGY
    Curtis Klaassen; Fiscal Year: 1999
    ..Both rats and humans are known to have seven major sulfotransferases. Rats have four phenol-sulfotransferases and three hydroxysteroid sulfotransferases, whereas humans have six phenol sulfotransferases and ..
  12. HEPATOBILIARY DISPOSITION IN TOXICOLOGY
    Curtis Klaassen; Fiscal Year: 2002
    ..Both rats and humans are known to have seven major sulfotransferases. Rats have four phenol-sulfotransferases and three hydroxysteroid sulfotransferases, whereas humans have six phenol sulfotransferases and ..
  13. HEPATOBILIARY DISPOSITION IN TOXICOLOGY
    Curtis Klaassen; Fiscal Year: 2000
    ..Both rats and humans are known to have seven major sulfotransferases. Rats have four phenol-sulfotransferases and three hydroxysteroid sulfotransferases, whereas humans have six phenol sulfotransferases and ..
  14. HEPATOBILIARY DISPOSITION IN TOXICOLOGY
    Curtis Klaassen; Fiscal Year: 2003
    ..Both rats and humans are known to have seven major sulfotransferases. Rats have four phenol-sulfotransferases and three hydroxysteroid sulfotransferases, whereas humans have six phenol sulfotransferases and ..
  15. HEPATOBILIARY DISPOSITION IN TOXICOLOGY
    Curtis Klaassen; Fiscal Year: 2001
    ..Both rats and humans are known to have seven major sulfotransferases. Rats have four phenol-sulfotransferases and three hydroxysteroid sulfotransferases, whereas humans have six phenol sulfotransferases and ..
  16. Silk Fibroin Small-Molecule Drug Carriers for the Treatment of Osteoarthritis
    TIMOTHY KARIITHI MWANGI; Fiscal Year: 2012
    ..Curcumin is a small di-phenol that inhibits inflammation in many cell types and will be used as a model drug here...
  17. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 2000
    The activation of pro-phenol oxidase is an important physiological process involved in defense mechanisms in insects...
  18. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 2001
    The activation of pro-phenol oxidase is an important physiological process involved in defense mechanisms in insects...
  19. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 1999
    The activation of pro-phenol oxidase is an important physiological process involved in defense mechanisms in insects...
  20. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 2000
    The activation of pro-phenol oxidase is an important physiological process involved in defense mechanisms in insects...
  21. Phase II Environmentally greener, efficient, and safe synthetic platform for the
    PAUL MATTHEW HERRINTON; Fiscal Year: 2010
    ..3. Augment the phenol portfolio to make more previously unreported products available. Increase the scale to produce kilogram quantities...
  22. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 2002
    The activation of pro-phenol oxidase is an important physiological process involved in defense mechanisms in insects...
  23. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 2003
    The activation of pro-phenol oxidase is an important physiological process involved in defense mechanisms in insects...
  24. MECHANISMS OF CARBON-CARBON LYASES AND KYNURENINASE
    Robert Phillips; Fiscal Year: 1992
    ..to understand, at the molecular level, the mechanisms of three of these enzymes, tryptophan indole-lyase, tyrosine phenol-lyase, and kynureninase...
  25. MECHANISMS OF CARBON-CARBON LYASES AND KYNURENINASE
    Robert Phillips; Fiscal Year: 1993
    ..to understand, at the molecular level, the mechanisms of three of these enzymes, tryptophan indole-lyase, tyrosine phenol-lyase, and kynureninase...
  26. MECHANISMS OF CARBON-CARBON LYASES AND KYNURENINASE
    Robert Phillips; Fiscal Year: 1990
    ..to understand, at the molecular level, the mechanisms of three of these enzymes, tryptophan indole-lyase, tyrosine phenol-lyase, and kynureninase...
  27. MECHANISMS OF CARBON-CARBON LYASES AND KYNURENINASE
    Robert Phillips; Fiscal Year: 1991
    ..to understand, at the molecular level, the mechanisms of three of these enzymes, tryptophan indole-lyase, tyrosine phenol-lyase, and kynureninase...
  28. Heme/Copper and Heme/Nonheme Iron O(2) and NO Reactivity
    KENNETH KARLIN; Fiscal Year: 2009
    ..chemical or biochemical systems, (3) the design of new ligands for copper which possess a linked phenol-imidazole moiety, to elucidate how such a group may take part in O-O cleavage chemistry, i.e., HCO function...
  29. Mechanisms of PVL-induced Acute Lung Injury
    Binh An Diep; Fiscal Year: 2010
    ..Aim 3. To determine the relative effects of PVL, -hemolysin (HLA), and -type phenol-soluble modulins (PSM-) on acute lung injury and necrotizing pneumonia in the rabbit model...
  30. Heme/Copper and Heme/Nonheme Iron O(2) and NO Reactivity
    Kenneth D Karlin; Fiscal Year: 2010
    ..chemical or biochemical systems, (3) the design of new ligands for copper which possess a linked phenol-imidazole moiety, to elucidate how such a group may take part in O-O cleavage chemistry, i.e., HCO function...
  31. DENTINOGENESIS IMPERFECTA
    Mary Macdougall; Fiscal Year: 1991
    ..a hemizygous interstitial deletion of the chromosome 4 ql3-q2l, to construct a regional genomic library using the phenol-enhanced differential reassociation (PERT) technique...
  32. Identification of Novel Broad Spectrum Influenza Virus Inhibitors
    Arnab Basu; Fiscal Year: 2012
    ..g., endosomal pH, or sialic acid residues or viral/cell membrane). MBX494, MBX994, and MBX726 have aminoalkyl phenol ether, aminoacetamide sulfonamide and simple sulfonamide scaffolds respectively...
  33. H-BONDS AND PROTON TRANSFER IN MODEL PIGMENT CHROMOPHORE
    PAUL BLATZ; Fiscal Year: 1990
    ..Some of the experimental variables to be studied are: i) donor reagents such as phenol, substituted phenols, acetic acid and chloro substituted acetic acids, ii) selected solvents such as hydrocarbons ..
  34. EPIDEMIOLOGIC STUDIES OF DIET AND CANCER IN HAWAII
    Laurence Kolonel; Fiscal Year: 2002
    ..and selected genetic markers in relation to colorectal cancer; 2) carotenoids, tocopherols, vitamin C, total phenol, isothiocyanates, selenium, and isoprostane in relation to lung cancer; 3) phytoestrogens, carotenoids, ..
  35. EPIDEMIOLOGIC STUDIES OF DIET AND CANCER IN HAWAII
    Laurence Kolonel; Fiscal Year: 2001
    ..and selected genetic markers in relation to colorectal cancer; 2) carotenoids, tocopherols, vitamin C, total phenol, isothiocyanates, selenium, and isoprostane in relation to lung cancer; 3) phytoestrogens, carotenoids, ..
  36. EPIDEMIOLOGIC STUDIES OF DIET AND CANCER IN HAWAII
    Laurence Kolonel; Fiscal Year: 2001
    ..and selected genetic markers in relation to colorectal cancer; 2) carotenoids, tocopherols, vitamin C, total phenol, isothiocyanates, selenium, and isoprostane in relation to lung cancer; 3) phytoestrogens, carotenoids, ..
  37. EPIDEMIOLOGIC STUDIES OF DIET AND CANCER IN HAWAII
    Laurence Kolonel; Fiscal Year: 2000
    ..and selected genetic markers in relation to colorectal cancer; 2) carotenoids, tocopherols, vitamin C, total phenol, isothiocyanates, selenium, and isoprostane in relation to lung cancer; 3) phytoestrogens, carotenoids, ..
  38. EPIDEMIOLOGIC STUDIES OF DIET AND CANCER IN HAWAII
    Laurence Kolonel; Fiscal Year: 2003
    ..and selected genetic markers in relation to colorectal cancer; 2) carotenoids, tocopherols, vitamin C, total phenol, isothiocyanates, selenium, and isoprostane in relation to lung cancer; 3) phytoestrogens, carotenoids, ..
  39. EPIDEMIOLOGIC STUDIES OF DIET AND CANCER IN HAWAII
    Laurence Kolonel; Fiscal Year: 2004
    ..and selected genetic markers in relation to colorectal cancer; 2) carotenoids, tocopherols, vitamin C, total phenol, isothiocyanates, selenium, and isoprostane in relation to lung cancer; 3) phytoestrogens, carotenoids, ..
  40. MECHANISMS OF PYRIDOXAL-5'-PHOSPHATE DEPENDENT ENZYMES
    Robert Phillips; Fiscal Year: 2000
    ..These enzymes include tryptophan indole-lyase, tyrosine phenol-lyase, tryptophan synthase, bacterial and human kynureninases, and aspartate beta-decarboxylase...
  41. MECHANISMS OF PYRIDOXAL-5'-PHOSPHATE DEPENDENT ENZYMES
    Robert Phillips; Fiscal Year: 2002
    ..These enzymes include tryptophan indole-lyase, tyrosine phenol-lyase, tryptophan synthase, bacterial and human kynureninases, and aspartate beta-decarboxylase...
  42. MECHANISMS OF PYRIDOXAL-5'-PHOSPHATE DEPENDENT ENZYMES
    Robert Phillips; Fiscal Year: 2003
    ..These enzymes include tryptophan indole-lyase, tyrosine phenol-lyase, tryptophan synthase, bacterial and human kynureninases, and aspartate beta-decarboxylase...
  43. MECHANISMS OF PYRIDOXAL-5'-PHOSPHATE DEPENDENT ENZYMES
    Robert Phillips; Fiscal Year: 2001
    ..These enzymes include tryptophan indole-lyase, tyrosine phenol-lyase, tryptophan synthase, bacterial and human kynureninases, and aspartate beta-decarboxylase...
  44. O2 ACTIVATION BY MOSSBAUER SPECTROSCOPY
    Eckard Munck; Fiscal Year: 2002
    ..of the diiron proteins methane monooxygenase, ribonucleotide reductase, delta9 desaturase, toluene monooxygenase, phenol hydroxylase and alkane hydroxylase will be continued with particular focus on characterizing the electronic ..
  45. GENETIC AND CYTOGENETIC STUDIES OF MENTAL RETARDATION
    Louis Kunkel; Fiscal Year: 1990
    ..which allow intense study of subchromosomal regions, such as fluorescence activated chromosome sorting and phenol-enhanced differential hybridization, recombinant DNA methodology, cytogenetics, somatic cell genetics and pedigree ..
  46. O2 ACTIVATION BY MOSSBAUER SPECTROSCOPY
    Eckard Munck; Fiscal Year: 2000
    ..of the diiron proteins methane monooxygenase, ribonucleotide reductase, delta9 desaturase, toluene monooxygenase, phenol hydroxylase and alkane hydroxylase will be continued with particular focus on characterizing the electronic ..
  47. Interaction of inhalational anesthetics with macromolecules
    Roderic Eckenhoff; Fiscal Year: 2009
    ..Another divergence from the original aims is that these studies now focus on alkyl phenol drugs (derivatives of propofol) and less emphasis is placed on volatile anesthetics. Strengths: Dr...
  48. O2 ACTIVATION BY MOSSBAUER SPECTROSCOPY
    Eckard Munck; Fiscal Year: 1999
    ..of the diiron proteins methane monooxygenase, ribonucleotide reductase, delta9 desaturase, toluene monooxygenase, phenol hydroxylase and alkane hydroxylase will be continued with particular focus on characterizing the electronic ..
  49. O2 ACTIVATION BY MOSSBAUER SPECTROSCOPY
    Eckard Munck; Fiscal Year: 2001
    ..of the diiron proteins methane monooxygenase, ribonucleotide reductase, delta9 desaturase, toluene monooxygenase, phenol hydroxylase and alkane hydroxylase will be continued with particular focus on characterizing the electronic ..
  50. Understanding coupled transfers of electrons and protons relevant to biological c
    James Mayer; Fiscal Year: 2009
    ..For example, the proposed studies of oxidation of phenol-base compounds will probe how framework motions affect hydrogen transfers, an issue of much current debate ..
  51. Understanding coupled transfers of electrons and protons relevant to biological c
    James Mayer; Fiscal Year: 2009
    ..For example, the proposed studies of oxidation of phenol-base compounds will probe how framework motions affect hydrogen transfers, an issue of much current debate ..
  52. Understanding coupled transfers of electrons and protons relevant to biological c
    James M Mayer; Fiscal Year: 2010
    ..For example, the proposed studies of oxidation of phenol-base compounds will probe how framework motions affect hydrogen transfers, an issue of much current debate ..
  53. ABSORPTION OF INHALED SUB-MICRON TRACE METALS
    Daniel Menzel; Fiscal Year: 1980
    ..Possible alterations of a well defined carrier mediated transport system in the lung, phenol red, will be investigated...
  54. MEMBRANE-BOUND DETOXICATION ENZYMES
    Richard Armstrong; Fiscal Year: 1993
    ..of UDP- glucuronosyltransferase include (i) construction of a baculovirus-based expression system for the phenol UDPGT and characterization of the immature and mature protein products and various truncated proteins; (ii) a ..
  55. Structure and Mechanisms of PLP Dependent Lyases
    Robert Phillips; Fiscal Year: 2005
    ..The carbon-carbon lyase, tyrosine phenol-lyase (EC 4.1.99...
  56. Structure and Mechanisms of PLP Dependent Lyases
    Robert Phillips; Fiscal Year: 2006
    ..The carbon-carbon lyase, tyrosine phenol-lyase (EC 4.1.99...
  57. Structure and Mechanisms of PLP Dependent Lyases
    Robert Phillips; Fiscal Year: 2004
    ..The carbon-carbon lyase, tyrosine phenol-lyase (EC 4.1.99...
  58. Understanding coupled transfers of electrons and protons relevant to biological c
    James Mayer; Fiscal Year: 2007
    ..For example, the proposed studies of oxidation of phenol-base compounds will probe how framework motions affect hydrogen transfers, an issue of much current debate ..
  59. Search for the Molecular Targets of Phenols
    CYNTHIA SELASSIE; Fiscal Year: 2006
    ..potentials in vitro, in order to delineate which apoptotic pathway (intrinsic or extrinsic) is compromised in phenol exposed cells...
  60. PROTEINASE SYSTEMS IN INSECT HEMOLYMPH
    Michael Kanost; Fiscal Year: 1999
    ..The specific aims of the project are: 1. Identify and characterize serine proteases involved in activation of pro-phenol oxidase. Proteases linked to activation of pro-phenol oxidase will be purified and characterized...
  61. PROTEINASE SYSTEMS IN INSECT HEMOLYMPH
    Michael Kanost; Fiscal Year: 2000
    ..The specific aims of the project are: 1. Identify and characterize serine proteases involved in activation of pro-phenol oxidase. Proteases linked to activation of pro-phenol oxidase will be purified and characterized...
  62. PROTEINASE SYSTEMS IN INSECT HEMOLYMPH
    Michael Kanost; Fiscal Year: 2001
    ..The specific aims of the project are: 1. Identify and characterize serine proteases involved in activation of pro-phenol oxidase. Proteases linked to activation of pro-phenol oxidase will be purified and characterized...
  63. LUNG TUMOR PROMOTION BY BHT
    ALVIN MALKINSON; Fiscal Year: 1993
    Promotion of mouse lung tumors by the antioxidant butylated hydroxytolune (BHT; 2,6,-di-tert-butyl-4-methyl phenol) has become a powerful system for understanding how a non-carcinogen enhances tumor growth in a internal organ...
  64. LUNG TUMOR PROMOTION BY BHT
    ALVIN MALKINSON; Fiscal Year: 1991
    Promotion of mouse lung tumors by the antioxidant butylated hydroxytolune (BHT; 2,6,-di-tert-butyl-4-methyl phenol) has become a powerful system for understanding how a non-carcinogen enhances tumor growth in a internal organ...
  65. ELECTRICAL AND CONTRACTILE PROPERTIES OF MUSCLE
    William Chandler; Fiscal Year: 1999
    ..In most experiments, the amount and time course of release will be measured with the EGTA-phenol red method. Currents from intramembranous change movement will be measured with the voltage-clamp method...
  66. GLUTATHIONE PATHWAY TO THE FORMATION OF PHENOLS
    KHINGKAN LERTRATANANGKOON; Fiscal Year: 1990
    ..This route to phenols may be the major mode of phenol formation for many aromatic compounds whose metabolism involve the reaction of oxides with glutathione...
  67. APPLICATION OF CRYSTALLOGRAPHIC TECHNIQUES
    JENNY GLUSKER; Fiscal Year: 2000
    ..Some ab initio molecular orbital studies of reaction pathways in the metabolism of benzene and phenol will also be carried out...
  68. APPLICATION OF CRYSTALLOGRAPHIC TECHNIQUES
    JENNY GLUSKER; Fiscal Year: 2001
    ..Some ab initio molecular orbital studies of reaction pathways in the metabolism of benzene and phenol will also be carried out...
  69. IMMUNOTOXICOLOGY OF BENZENE METABOLITES
    Brian Freed; Fiscal Year: 1993
    ..1) To assess the role of macrophages and peroxidases in the immunosuppressive effects of the benzene metabolites, phenol, hydroquinol (HQ), and p-BQ; (2) To measure the effects of benzene metabolites on the expression of genes encoding ..
  70. NOVEL REDOX PROTEINS FROM SULFATE REDUCING BACT
    Boi Hanh Huynh; Fiscal Year: 1993
    ..the catalysis of a variety of important biological functions, including oxygen transport, methane hydroxylation, phenol oxidation, and hydrolysis of phosphate esters...
  71. NOVEL REDOX PROTEINS FROM SULFATE REDUCING BACT
    Boi Hanh Huynh; Fiscal Year: 1992
    ..the catalysis of a variety of important biological functions, including oxygen transport, methane hydroxylation, phenol oxidation, and hydrolysis of phosphate esters...
  72. BIOSYNTHESIS OF NEUROPHYSINS
    TING CHI WUU; Fiscal Year: 1980
    ..b>Phenol-chloroform-sodium dodecyl sulfate extraction followed by affinity chromatography on oligo-(dT) cellulose column ..
  73. FLAVONOIDS BLOCK SULFATION-INDUCED CARCINOGEN ACTIVATION
    Thomas Walle; Fiscal Year: 1999
    ..Aim 1 will investigate the structure-activity relationship and kinetics for inhibition of human P form phenol-ST (P-PST) and dehydroepiandrosterone-ST (DHEA-ST) by flavonoids, using recombinant enzymes, model substrates for ..
  74. ELECTROSTATICS AND DYNAMICS IN MYOGLOBIN MUTANTS
    STEVEN BOXER; Fiscal Year: 2003
    ..histidine in Mb with a very wide range of small organic ligands including methyl-substituted imidazoles, pyridine, phenol, furan, thiophene, and ethanethiol. With this method it is possible to radically alter the properties of Mb...
  75. ACTIVE SITE STUDIES OF HUMAN SULFOTRANSFERASES
    Guangping Chen; Fiscal Year: 2001
    ..probes to identify amino acid residues in both the substrate- binding site and PAPS binding site of human liver phenol- sulfating ST (P-PST-1), dehydroepiandrosterone ST (DHEA-ST), and estrogen ST (EST). 2...
  76. ELECTROSTATICS AND DYNAMICS IN MYOGLOBIN MUTANTS
    STEVEN BOXER; Fiscal Year: 2002
    ..histidine in Mb with a very wide range of small organic ligands including methyl-substituted imidazoles, pyridine, phenol, furan, thiophene, and ethanethiol. With this method it is possible to radically alter the properties of Mb...
  77. ACTIVE SITE STUDIES OF HUMAN SULFOTRANSFERASES
    Guangping Chen; Fiscal Year: 2000
    ..probes to identify amino acid residues in both the substrate- binding site and PAPS binding site of human liver phenol- sulfating ST (P-PST-1), dehydroepiandrosterone ST (DHEA-ST), and estrogen ST (EST). 2...
  78. ELECTROSTATICS AND DYNAMICS IN MYOGLOBIN MUTANTS
    STEVEN BOXER; Fiscal Year: 2000
    ..histidine in Mb with a very wide range of small organic ligands including methyl-substituted imidazoles, pyridine, phenol, furan, thiophene, and ethanethiol. With this method it is possible to radically alter the properties of Mb...
  79. ACTIVE SITE STUDIES OF HUMAN SULFOTRANSFERASES
    Guangping Chen; Fiscal Year: 2003
    ..probes to identify amino acid residues in both the substrate- binding site and PAPS binding site of human liver phenol- sulfating ST (P-PST-1), dehydroepiandrosterone ST (DHEA-ST), and estrogen ST (EST). 2...
  80. ACTIVE SITE STUDIES OF HUMAN SULFOTRANSFERASES
    Guangping Chen; Fiscal Year: 2002
    ..probes to identify amino acid residues in both the substrate- binding site and PAPS binding site of human liver phenol- sulfating ST (P-PST-1), dehydroepiandrosterone ST (DHEA-ST), and estrogen ST (EST). 2...
  81. ELECTROSTATICS AND DYNAMICS IN MYOGLOBIN MUTANTS
    STEVEN BOXER; Fiscal Year: 2001
    ..histidine in Mb with a very wide range of small organic ligands including methyl-substituted imidazoles, pyridine, phenol, furan, thiophene, and ethanethiol. With this method it is possible to radically alter the properties of Mb...
  82. ELECTROSTATICS AND DYNAMICS IN MYOGLOBIN MUTANTS
    STEVEN BOXER; Fiscal Year: 2003
    ..histidine in Mb with a very wide range of small organic ligands including methyl-substituted imidazoles, pyridine, phenol, furan, thiophene, and ethanethiol. With this method it is possible to radically alter the properties of Mb...