Summary: An antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. It has been used to disinfect skin and to relieve itching. (From Martindale, The Extra Pharmacopoeia, 30th ed, p801)

Top Publications

  1. ncbi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    P Chomczynski
    Anal Biochem 162:156-9. 1987
  2. ncbi The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on
    Piotr Chomczynski
    Molecular Research Center, 2600 Clifton Avenue, Cincinnati, Ohio 45221, USA
    Nat Protoc 1:581-5. 2006
  3. pmc Prenatal phenol and phthalate exposures and birth outcomes
    Mary S Wolff
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Environ Health Perspect 116:1092-7. 2008
  4. pmc Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles
    Bas G J Surewaard
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS Pathog 8:e1002606. 2012
  5. ncbi Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries
    N Hobara
    Department of Clinical Pharmaceutical Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1 1 1 Tsushima naka, Okayama 700 8530, Japan
    Neuroscience 150:730-41. 2007
  6. pmc Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization
    Ingrid C McCall
    Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Toxicol Appl Pharmacol 241:61-70. 2009
  7. pmc Analysis of current and alternative phenol based RNA extraction methodologies for cyanobacteria
    Fernando Lopes Pinto
    Department of Photochemistry and Molecular Science, The Angstrom Laboratories, Uppsala University, Box 523, SE 75120, Uppsala, Sweden
    BMC Mol Biol 10:79. 2009
  8. pmc Group-specific monitoring of phenol hydroxylase genes for a functional assessment of phenol-stimulated trichloroethylene bioremediation
    H Futamata
    Marine Biotechnology Institute, Kamaishi Laboratories, Heita, Kamaishi City, Iwate 026-0001, Japan
    Appl Environ Microbiol 67:4671-7. 2001
  9. pmc Population dynamics of phenol-degrading bacteria in activated sludge determined by gyrB-targeted quantitative PCR
    K Watanabe
    Corporate Research and Development Laboratories, Tonen Corporation, Saitama, Japan
    Appl Environ Microbiol 64:1203-9. 1998
  10. ncbi Bioenergetic strategy of microalgae for the biodegradation of phenolic compounds: exogenously supplied energy and carbon sources adjust the level of biodegradation
    Aikaterini Papazi
    Department of Biology, University of Crete, Heraklion, Crete, Greece
    J Biotechnol 129:706-16. 2007

Detail Information

Publications368 found, 100 shown here

  1. ncbi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    P Chomczynski
    Anal Biochem 162:156-9. 1987
    A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described. The method provides a pure preparation of undegraded RNA in high yield and can be completed within 4 h...
  2. ncbi The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on
    Piotr Chomczynski
    Molecular Research Center, 2600 Clifton Avenue, Cincinnati, Ohio 45221, USA
    Nat Protoc 1:581-5. 2006 separated from DNA after extraction with an acidic solution containing guanidinium thiocyanate, sodium acetate, phenol and chloroform, followed by centrifugation...
  3. pmc Prenatal phenol and phthalate exposures and birth outcomes
    Mary S Wolff
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Environ Health Perspect 116:1092-7. 2008
    ..Many phthalates and phenols are hormonally active and are suspected to alter the course of development...
  4. pmc Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles
    Bas G J Surewaard
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS Pathog 8:e1002606. 2012
    Staphylococcus aureus virulence has been associated with the production of phenol soluble modulins (PSM). PSM are known to activate, attract and lyse neutrophils...
  5. ncbi Angiotensin II type 2 receptors facilitate reinnervation of phenol-lesioned vascular calcitonin gene-related peptide-containing nerves in rat mesenteric arteries
    N Hobara
    Department of Clinical Pharmaceutical Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1 1 1 Tsushima naka, Okayama 700 8530, Japan
    Neuroscience 150:730-41. 2007
    ..II (Ang II) type 2 receptors (AT2 receptors) in restoration of perivascular nerve innervation injured by topical phenol treatment...
  6. pmc Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization
    Ingrid C McCall
    Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Toxicol Appl Pharmacol 241:61-70. 2009
    b>Phenol contamination of soil and water has raised concerns among people living near phenol-producing factories and hazardous waste sites containing the chemical...
  7. pmc Analysis of current and alternative phenol based RNA extraction methodologies for cyanobacteria
    Fernando Lopes Pinto
    Department of Photochemistry and Molecular Science, The Angstrom Laboratories, Uppsala University, Box 523, SE 75120, Uppsala, Sweden
    BMC Mol Biol 10:79. 2009
    ..Therefore, we used the NHM5 strain of Nostoc punctiforme ATCC 29133 to compare and improve existing phenol based chemistry and procedures for RNA extraction.
  8. pmc Group-specific monitoring of phenol hydroxylase genes for a functional assessment of phenol-stimulated trichloroethylene bioremediation
    H Futamata
    Marine Biotechnology Institute, Kamaishi Laboratories, Heita, Kamaishi City, Iwate 026-0001, Japan
    Appl Environ Microbiol 67:4671-7. 2001
    The sequences of the largest subunit of bacterial multicomponent phenol hydroxylases (LmPHs) were compared...
  9. pmc Population dynamics of phenol-degrading bacteria in activated sludge determined by gyrB-targeted quantitative PCR
    K Watanabe
    Corporate Research and Development Laboratories, Tonen Corporation, Saitama, Japan
    Appl Environ Microbiol 64:1203-9. 1998
    ..The adequacy of the method was examined by analyzing the population dynamics of two phenol-degrading bacteria, Pseudomonas putida BH and Comamonas sp...
  10. ncbi Bioenergetic strategy of microalgae for the biodegradation of phenolic compounds: exogenously supplied energy and carbon sources adjust the level of biodegradation
    Aikaterini Papazi
    Department of Biology, University of Crete, Heraklion, Crete, Greece
    J Biotechnol 129:706-16. 2007
    ..of microalgae incubated with phenols, it can be assumed that, at least in low concentrations, phenol have no toxic effects on the cultures and can be used as alternative carbon source in them...
  11. ncbi Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells
    Nobuhiro Ikezawa
    Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo, Kyoto, Japan
    J Biol Chem 283:8810-21. 2008
    ..several unique P450 reactions have been reported, such as methylenedioxy bridge formation, intramolecular C-C phenol-coupling and intermolecular C-O phenol-coupling reactions...
  12. ncbi Evaluation of the antioxidant properties of litchi fruit phenolics in relation to pericarp browning prevention
    Xuewu Duan
    South China Botanical Garden, The Chinese Academy of Sciences, Guangzhou Leyiju 510650, PR China
    Molecules 12:759-71. 2007
    ..These results suggest that litchi pericarp tissue phenolics could be beneficial in scavenging free radicals, maintaining membrane integrity and, thereby inhibiting pericarp browning of litchi fruit...
  13. pmc Oxidation of benzene to phenol, catechol, and 1,2,3-trihydroxybenzene by toluene 4-monooxygenase of Pseudomonas mendocina KR1 and toluene 3-monooxygenase of Ralstonia pickettii PKO1
    Ying Tao
    Department of Chemical Engineering, University of Connecticut, Storrs, CT 06269 3222, USA
    Appl Environ Microbiol 70:3814-20. 2004
    ..of Ralstonia pickettii PKO1, and toluene ortho-monooxygenase (TOM) of Burkholderia cepacia G4 convert benzene to phenol, catechol, and 1,2,3-trihydroxybenzene by successive hydroxylations...
  14. ncbi Response of Pseudomonas putida KT2440 to phenol at the level of membrane proteome
    Catarina Roma-Rodrigues
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Lisboa, Portugal
    J Proteomics 73:1461-78. 2010
    ..led to the extension and refinement of our current model for the global response of Pseudomonas putida KT2440 to phenol by getting insights into the adaptive response mechanisms involving the membrane proteome...
  15. ncbi Antioxidant activities of estrogens against aqueous and lipophilic radicals; differences between phenol and catechol estrogens
    M B Ruiz-Larrea
    Departamento de Fisiologia, Facultad de Medicina, Universidad del Pais Vasco UPV EHU, Bilbao, Spain
    Chem Phys Lipids 105:179-88. 2000
    ..The antioxidant activity of an estrogen depends not only on the hydrophilic or lipophilic nature of the scavenged radical, but also on the phenol and catechol structures of the estrogen compound.
  16. ncbi A cytomic approach reveals population heterogeneity of Cupriavidus necator in response to harmful phenol concentrations
    Claudia Wiacek
    Department of Environmental Microbiology, UFZ Centre for Environmental Research Leipzig Halle, Leipzig, Germany
    Proteomics 6:5983-94. 2006
    ..Betaproteobacterium Cupriavidus necator dramatically altered its population heterogeneity in response to harmful phenol concentrations...
  17. ncbi Semicontinuous Fenton oxidation of phenol in aqueous solution. A kinetic study
    J A Zazo
    Ingenieria Quimica, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Water Res 43:4063-9. 2009
    This work investigates the Fenton oxidation of phenol in a semicontinuous reactor where the overall amount of H(2)O(2) is distributed as a continuous feed upon the reaction time...
  18. ncbi Grouping of phenol hydroxylase and catechol 2,3-dioxygenase genes among phenol- and p-cresol-degrading Pseudomonas species and biotypes
    Merike Merimaa
    Department of Genetics, Institute of Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu, Estonia
    Arch Microbiol 186:287-96. 2006
    b>Phenol- and p-cresol-degrading pseudomonads isolated from phenol-polluted water were analysed by the sequences of a large subunit of multicomponent phenol hydroxylase (LmPH) and catechol 2,3-dioxygenase (C23O), as well as according to the ..
  19. ncbi Phenol degradation in water through a heterogeneous photo-Fenton process catalyzed by Fe-treated laponite
    B Iurascu
    Facultatea de Inginerie Chimica, Universitatea Tehnica Gh Asachi, Iasi, Romania
    Water Res 43:1313-22. 2009
    ..The catalysts were used for photo-assisted Fenton conversion of phenol, analyzing the influence of five operating factors: the wavelength of the light source (254 nm UV-C and 360 UV-A ..
  20. ncbi Comparative lipidomics of four strains of Saccharomyces cerevisiae reveals different responses to furfural, phenol, and acetic acid
    Jin Mei Xia
    Key Laboratory of Systems Bioengineering, Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin, People s Republic of China
    J Agric Food Chem 57:99-108. 2009
    ..cerevisiae to furfural, phenol, and acetic acid, comparative lipidomics strategy was employed using an LC-ESI/MS(n) technique on four S...
  21. ncbi Enrichment and cultivation of pelagic bacteria from a humic lake using phenol and humic matter additions
    Kristine Michelle L Hutalle-Schmelzer
    Department of Limnology of Stratified Lakes, Leibniz Institute of Freshwater Ecology and Inland Fisheries, Stechlin, Germany
    FEMS Microbiol Ecol 72:58-73. 2010
    ..To test how the availability of either pure phenol or natural humic matter (HM) selects for specific pelagic bacteria phylotypes from a humic lake (Lake Grosse ..
  22. ncbi The removal of phenol from aqueous solutions by adsorption using surfactant-modified bentonite and kaolinite
    Uday F Alkaram
    Department of Chemistry, College of Education, Ibn Al Haitham, University of Baghdad, Baghdad, Iraq
    J Hazard Mater 169:324-32. 2009
    ..The ability of raw and organo-modified clays to remove phenol from aqueous solutions has been carried out as a function of contact time, pH and temperatures using a batch ..
  23. ncbi Insights into Pseudomonas putida KT2440 response to phenol-induced stress by quantitative proteomics
    Pedro M Santos
    Biological Sciences Research Group, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico IST, Lisboa, Portugal
    Proteomics 4:2640-52. 2004
    To gain insight into the global mechanism underlying phenol toxicity and tolerance in bacteria, we have generated a two-dimensional protein reference map and used it to identify variations in protein expression levels in Pseudomonas ..
  24. ncbi Integrated phospholipidomics and transcriptomics analysis of Saccharomyces cerevisiae with enhanced tolerance to a mixture of acetic acid, furfural, and phenol
    Jie Yang
    Key Laboratory of Systems Bioengineering, Ministry of Education Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, PR China
    OMICS 16:374-86. 2012
    A mixture of acetic acid, furfural, and phenol (AFP), three representative lignocellulose-derived inhibitors, significantly inhibited the growth and bioethanol production of Saccharomyces cerevisiae...
  25. pmc Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1
    Christine E Tinberg
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
    Biochemistry 50:1788-98. 2011
    b>Phenol hydroxylase (PH) and toluene/o-xylene monooxygenase (ToMO) from Pseudomonas sp. OX1 require three or four protein components to activate dioxygen for the oxidation of aromatic substrates at a carboxylate-bridged diiron center...
  26. pmc Acquisition of a deliberately introduced phenol degradation operon, pheBA, by different indigenous Pseudomonas species
    M Peters
    Department of Genetics, University of Tartu, Estonia
    Appl Environ Microbiol 63:4899-906. 1997
    ..Expression of the gene pheA, which encodes phenol monooxygenase and is linked to the pheBA operon (A. Nurk, L. Kasak, and M...
  27. ncbi Hologram QSAR models of 4-[(diethylamino)methyl]-phenol inhibitors of acetyl/butyrylcholinesterase enzymes as potential anti-Alzheimer agents
    Simone Decembrino de Souza
    Laboratory of Molecular Modeling and QSAR 3D ModMolQSAR, Faculty of Pharmacy, Federal University of Rio de Janeiro UFRJ, Rio de Janeiro, 21949 900, RJ, Brazil
    Molecules 17:9529-39. 2012
    ..Both the HQSAR models and the contribution maps should be useful for the further design of novel, structurally related cholinesterase inhibitors...
  28. ncbi Artificial neural network modeling in competitive adsorption of phenol and resorcinol from water environment using some carbonaceous adsorbents
    R M Aghav
    Civil Engineering Department, Jadavpur University, Kolkata 700 032, West Bengal, India
    J Hazard Mater 188:67-77. 2011
    ..the application of artificial neural network (ANN) for prediction of performances in competitive adsorption of phenol and resorcinol from aqueous solution by conventional and low cost carbonaceous adsorbent materials, such as ..
  29. pmc Ligand escape pathways and (un)binding free energy calculations for the hexameric insulin-phenol complex
    Harish Vashisth
    Department of Chemical and Biological Engineering, Drexel University, Philadelphia, Pennsylvania, USA
    Biophys J 95:4193-204. 2008
    ..b>Phenol dissociation is rapid on hexamer dissolution timescales, and phenol unbinding upon dilution is likely the first ..
  30. ncbi Cell-based biosensor for measurement of phenol and nitrophenols toxicity
    Chang Liu
    State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
    Talanta 84:766-70. 2011
    A cost-effective whole cell biosensor based on electrochemical technique to detect toxicities of phenol and nitrophenols has been developed...
  31. ncbi Phenol-oxidizing laccases from the termite gut
    M R Coy
    Department of Entomology and Nematology, University of Florida, Gainesville, FL 32611, USA
    Insect Biochem Mol Biol 40:723-32. 2010
    ..These findings contribute to a better understanding of termite digestion and gut physiology, and will assist future translational studies that examine the contributions of individual termite enzymes in lignocellulose digestion...
  32. ncbi Adaptation of Comamonas testosteroni TA441 to utilize phenol: organization and regulation of the genes involved in phenol degradation
    H Arai
    Laboratory of Microbiology, Institute of Physical and Chemical Research RIKEN, Saitama, Japan
    Microbiology 144:2895-903. 1998
    Comamonas testosteroni TA441 was not able to grow on phenol as a sole carbon and energy source, but it gained the ability to utilize phenol after a 2-3-week incubation in a medium containing phenol...
  33. ncbi Alternative surgical treatment for giant-cell reparative granuloma in the metacarpal, using phenol and ethanol adjuvant therapy
    Tatsuya Yoshida
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    J Hand Surg Am 32:887-92. 2007
    ..Adjuvant therapy usually is applied to reduce the recurrence of locally aggressive bone tumors. We report 2 cases of GCRG that were treated successfully with curettage, adjuvant phenol and ethanol, and autogenous bone grafting.
  34. ncbi Phenol as an adjuvant for local control in the treatment of giant cell tumour of the bone
    H R Dürr
    Department of Orthopedics and Orthopedic Surgery, Ludwig Maximilians University Munich, Klinikum Grosshadern, Marchioninistr 15, Munich, D 81366, Germany
    Eur J Surg Oncol 25:610-8. 1999
    ..Due to the combined use of phenol and cementation in most studies, the effect of phenol alone is described in this study.
  35. ncbi The thermophilic archaeon Sulfolobus solfataricus is able to grow on phenol
    Viviana Izzo
    Dipartimento di Biologia Strutturale e Funzionale, Universita di Napoli Federico II, Complesso Universitario di Monte S Angelo, Via Cinthia, 80126 Naples, Italy
    Res Microbiol 156:677-89. 2005
    ..In this paper we report that S. solfataricus can efficiently grow on phenol as the sole source of carbon and energy...
  36. ncbi Differential gene expression in response to phenol and catechol reveals different metabolic activities for the degradation of aromatic compounds in Bacillus subtilis
    Le Thi Tam
    Institut fur Mikrobiologie, Ernst Moritz Arndt Universitat Greifswald, F L Jahn Strasse 15, D 17487 Greifswald, Germany
    Environ Microbiol 8:1408-27. 2006
    ..We report here the global response of Bacillus subtilis 168 to phenol and catechol using proteome and transcriptome analyses...
  37. ncbi Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity
    Shaohua Ye
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Am J Hypertens 15:717-24. 2002
    Intrarenal injection of phenol in rats causes a persistent elevation in blood pressure (BP) and in norepinephrine (NE) secretion from the posterior hypothalamus (PH), and downregulation of neuronal nitric oxide synthase (nNOS) and ..
  38. ncbi Effect of activated carbons modification on porosity, surface structure and phenol adsorption
    G G Stavropoulos
    Chemical Engineering Department, Aristotle University of Thessaloniki, TEI campus, P O Box 1520, 54006 Thessaloniki, Greece
    J Hazard Mater 151:414-21. 2008
    ..Urea treated samples with a basic character and high nitrogen content presented the highest phenol uptake capacity; nitric acid treated carbons and oxygen gasified samples presented an acidic surface functionality ..
  39. ncbi Kinetics of phenol and chlorophenol utilization by Acinetobacter species
    Oliver J Hao
    Department of Civil and Environmental Engineering, University of Maryland, College Park 20742, USA
    Chemosphere 46:797-807. 2002
    ..The present study investigated the degradation kinetics of self-inhibitory growth (phenol) and nongrowth (4-chlorophenol, 4-CP) substrates, present individually and in combination...
  40. ncbi Oxidative stress mediates the stimulation of sympathetic nerve activity in the phenol renal injury model of hypertension
    Shaohua Ye
    Division of Nephrology, Hypertension Center, Keck School of Medicine, University of Southern California, 1200 North State St, Los Angeles, CA 90033, USA
    Hypertension 48:309-15. 2006
    Renal injury caused by the injection of phenol in the lower pole of one kidney increases blood pressure (BP), norepinephrine secretion from the posterior hypothalamic nuclei (PH), and renal sympathetic nerve activity in the rat...
  41. ncbi The cyo operon of Pseudomonas putida is involved in carbon catabolite repression of phenol degradation
    L Petruschka
    , , , Greifswald, Germany
    Mol Genet Genomics 266:199-206. 2001
    ..of the promoterless genes aacC1 (conferring gentamycin resistance) and lacZ fused to the catabolic promoter of the phenol degradation genes was used to identify and analyse mutants of Pseudomonas putida with altered carbon catabolite ..
  42. pmc Engineering of solvent-tolerant Pseudomonas putida S12 for bioproduction of phenol from glucose
    Nick J P Wierckx
    TNO Quality of Life, P O Box 342, 7300 AH Apeldoorn, The Netherlands
    Appl Environ Microbiol 71:8221-7. 2005
    Efficient bioconversion of glucose to phenol via the central metabolite tyrosine was achieved in the solvent-tolerant strain Pseudomonas putida S12...
  43. ncbi Local recurrence of giant cell tumor of bone after intralesional treatment with and without adjuvant therapy
    Wolfgang T Becker
    Orthopädische Klinik Volmarstein, Universitat Witten Herdecke, Wetter, Germany
    J Bone Joint Surg Am 90:1060-7. 2008
    ..The purpose of this study was to analyze the rates of recurrence following different types of treatment as well as the influence of various factors of tumor presentation on those rates...
  44. pmc The impact of ColRS two-component system and TtgABC efflux pump on phenol tolerance of Pseudomonas putida becomes evident only in growing bacteria
    Marta Putrins
    Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia
    BMC Microbiol 10:110. 2010
    We have recently found that Pseudomonas putida deficient in ColRS two-component system is sensitive to phenol and displays a serious defect on solid glucose medium where subpopulation of bacteria lyses...
  45. ncbi Quantitative structure-activity relationships in prooxidant cytotoxicity of polyphenols: role of potential of phenoxyl radical/phenol redox couple
    Ausra Nemeikaite-Ceniene
    Institute of Immunology of Vilnius University, Moletu pl 29, LT 08409 Vilnius, Lithuania
    Arch Biochem Biophys 441:182-90. 2005
    The aim of this work was to characterize the role of the potential of phenoxyl radical/phenol redox couple, E(7)(2), in the cytotoxicity of polyphenols...
  46. pmc RNA stable isotope probing, a novel means of linking microbial community function to phylogeny
    Mike Manefield
    CEH Oxford, Oxford OX1 3SR, United Kingdom
    Appl Environ Microbiol 68:5367-73. 2002
    ..In this study stable-isotope-labeled [13C]phenol was fed into a phenol-degrading community from an aerobic industrial bioreactor, and the 13C-labeled RNA produced ..
  47. ncbi Antioxidant activity, phenol and flavonoid contents of 13 citrus species peels and tissues
    Kamran Ghasemi
    Department of Horticulture, Faculty of Agriculture, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran
    Pak J Pharm Sci 22:277-81. 2009
    ..3 to 31.1 mg quercetin equivalent/g of extract. There were no correlation between the total phenolic and/or flavonoids contents and antioxidant activity in tissues and/or peels...
  48. pmc Syntrophorhabdus aromaticivorans gen. nov., sp. nov., the first cultured anaerobe capable of degrading phenol to acetate in obligate syntrophic associations with a hydrogenotrophic methanogen
    Yan Ling Qiu
    Bio Measurement Research Group, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Appl Environ Microbiol 74:2051-8. 2008
    b>Phenol degradation under methanogenic conditions has long been studied, but the anaerobes responsible for the degradation reaction are still largely unknown. An anaerobe, designated strain UI(T), was isolated in a pure syntrophic culture...
  49. ncbi Degradation of phenol by Acinetobacter strain isolated from aerobic granules
    Sunil S Adav
    Department of Chemical Engineering, National Taiwan University, No 1, Sec 4, Roosevelt Road, Taipei 10617, Taiwan
    Chemosphere 67:1566-72. 2007
    Aerobic granules effectively degrade phenol at high concentrations from which no Acinetobacter species, that can effectively degrade high concentrations of phenol, have ever been isolated from aerobic granules...
  50. ncbi Chemical pathway and kinetics of phenol oxidation by Fenton's reagent
    J A Zazo
    Ingenieria Quimica, Universidad Autonoma de Madrid, Spain
    Environ Sci Technol 39:9295-302. 2005
    b>Phenol oxidation by Fenton's reagent (H2O2 + Fe2+) in aqueous solution has been studied in depth for the purpose of learning more about the reactions involved and the extent of the oxidation process, under various operating conditions...
  51. ncbi Immuno-biochemical evaluations of phenol and thimerosal as antigen preservatives in Montenegro skin test
    Wilson Mayrink
    Universidade Federal de Minas Gerais, Instituto de Ciencias Biologicas, Depto de Parasitologia, Brazil
    Acta Trop 98:87-93. 2006
    ..In the search for an alternative stabilizer, phenol and thimerosal were tested as antigen preservatives in MST...
  52. ncbi Structure of the phenol-soluble polysaccharide from Shewanella putrefaciens strain A6
    Alexander S Shashkov
    Arrhenius Laboratory, Department of Organic Chemistry, Stockholm University, Sweden
    Carbohydr Res 337:1119-27. 2002
    The structure of the phenol-soluble polysaccharide from Shewanella putrefaciens strain A6 has been elucidated...
  53. ncbi Biosorption of phenol and chlorophenols by acclimated residential biomass under bioremediation conditions in a sandy aquifer
    B Antizar-Ladislao
    Technion, Israel Institute of Technology, Faculty of Civil and Environmental Engineering, Haifa 32000, Israel
    Water Res 38:267-76. 2004
    b>Phenol and chlorophenols are common environmental contaminants...
  54. ncbi Kinetic parameters of continuous cultures of Bacillus thermoleovorans sp. A2 degrading phenol at 65 degrees C
    Heiko Feitkenhauer
    Laboratory of Chemical Engineering and Industrial Chemistry, ETH Zurich, Honggerberg, CH 8093 Zurich, Switzerland
    J Biotechnol 103:129-35. 2003
    In this paper, we report on the kinetics of phenol degradation and cell growth in continuous cultures of suspended cells of Bacillus thermoleovorans sp. A2 at 65 degrees C. A high yield coefficient of Y(x/s)=0...
  55. ncbi Changes in structure, activity and metabolism of aerobic granules as a microbial response to high phenol loading
    H L Jiang
    Environmental Engineering Research Centre, School of Civil and Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore
    Appl Microbiol Biotechnol 63:602-8. 2004
    Four column-type sequential aerobic sludge blanket reactors were fed with phenol as the sole carbon and energy source and operated at loading rates of 1.0, 1.5, 2.0 and 2.5 kg phenol m(-3) day(-1)...
  56. ncbi An enzymatic method for removal of phenol from industrial effluent
    Naresh Singh
    Center for Biochemical Technology CSIR, Delhi University Campus, India
    Prep Biochem Biotechnol 32:127-33. 2002
    ..b>Phenol-containing industrial wastewater was treated with immobilized turnip peroxidase in the presence of hydrogen ..
  57. ncbi Effects of aeration intensity on formation of phenol-fed aerobic granules and extracellular polymeric substances
    Sunil S Adav
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Appl Microbiol Biotechnol 77:175-82. 2007
    ..No correlation was noted between extracellular polymeric substances composition and the proliferation of filamentous microorganisms on granule surface...
  58. ncbi 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) inhibits peroxynitrite-mediated phenol nitration
    R T Carroll
    Neuroscience Therapeutics, Parke Davis Pharmaceutical Research, Division of Warner Lambert Company, Ann Arbor, Michigan 48105, USA
    Chem Res Toxicol 13:294-300. 2000
    ..This complex could react with water to form either nitrite or nitrate, or with a phenol radical to produce nitrophenol or nitrosophenol products and regenerate the nitroxide.
  59. ncbi A mechanistic kinetic model for phenol degradation by the Fenton process
    Ricardo F F Pontes
    Chemical Engineering Department, Universidade de Sao Paulo, Av Prof Luciano Gualberto, Travessa 3, 380, 05508 900, Sao Paulo, SP, Brazil
    J Hazard Mater 176:402-13. 2010
    The objective of this paper is to develop and validate a mechanistic model for the degradation of phenol by the Fenton process...
  60. ncbi Enhanced degradation of phenol by Pseudomonas sp. CP4 entrapped in agar and calcium alginate beads in batch and continuous processes
    P Y Aneez Ahamad
    Department of Food Microbiology, Central Food Technological Research Institute, Mysore, 570 013, India
    Biodegradation 22:253-65. 2011
    b>Phenol is one of the major toxic pollutants in the wastes generated by a number of industries and needs to be eliminated before their discharge...
  61. ncbi Portable surface-enhanced Raman scattering sensor for rapid detection of aniline and phenol derivatives by on-site electrostatic preconcentration
    Dan Li
    Key Laboratory for Advanced Materials and Department of Chemistry, East China University of Science and Technology, Shanghai 200237, People s Republic of China
    Anal Chem 82:9299-305. 2010
    ..surface-enhanced Raman scattering (SERS) sensor is developed and applied to simultaneous detection of aniline and phenol derivatives in a label-free way with an electrostatic preconcentration technique to amplify the signals...
  62. ncbi Simple and rapid method for the analysis of phenolic compounds in beverages and grains
    Marjorie B Medina
    Residue Chemistry and Predictive Microbiology Research Unit, Eastern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, United States
    J Agric Food Chem 59:1565-71. 2011
    ..This method is simple and inexpensive and can be used to rapidly assess the total phenolics of foods and beverages...
  63. ncbi Theoretical evaluation of isotopic fractionation factors in oxidation reactions of benzene, phenol and chlorophenols
    Paweł Adamczyk
    Institute of Applied Radiation Chemistry, Faculty of Chemistry, Technical University of Lodz, Zeromskiego 116, 90 924, Lodz, Poland
    J Mol Model 17:2285-96. 2011
    ..of benzene with permanganate, perchlorate, ozone and dioxygen in the gas phase and aqueous solution as well as phenol and dichlorophenol in protonated and unprotonated forms in aqueous solution...
  64. pmc Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry
    David J Gonzalez
    Department of Pediatrics, University of California at San Diego, La Jolla, California 92093, USA
    J Biol Chem 287:13889-98. 2012
    ..aureus (CA-MRSA) with homology to the phenol-soluble modulins (PSMs) from Staphylococcus epidermidis...
  65. pmc Current production in a microbial fuel cell using a pure culture of Cupriavidus basilensis growing in acetate or phenol as a carbon source
    Hen Friman
    Department of Chemical Engineering and Biotechnology, Ariel University Center, Ariel, 40700, Israel
    Microb Biotechnol 6:425-34. 2013
    ..Cupriavidus basilensis bacterial cells growing in the anode compartment in a defined medium containing acetate or phenol. Operating this mediator-less MFC under a constant external resistor of 1 kΩ with acetate or phenol led to ..
  66. pmc Insight into structure-function relationship in phenol-soluble modulins using an alanine screen of the phenol-soluble modulin (PSM) α3 peptide
    Gordon Y C Cheung
    3National Institute of Allergy and Infectious Diseases, 9000 Rockville Pike, Bldg 33 1W10, Bethesda, MD 20892, USA
    FASEB J 28:153-61. 2014
    b>Phenol-soluble modulins (PSMs) are a family of peptides with multiple functions in staphylococcal pathogenesis...
  67. ncbi Degradation of phenol by the collapse of microbubbles
    Pan Li
    National Institute of Advanced Industrial Science and Technology, 16 1, Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Chemosphere 75:1371-5. 2009
    ..We have verified that collapsing air microbubbles lead to the decomposition of phenol, a common pollutant...
  68. ncbi Amperometric phenol biosensor based on horseradish peroxidase entrapped PVF and PPy composite film coated GC electrode
    Meral Topcu Sulak
    Department of Environmental Engineering, Gebze Institute of Technology, 41400 Gebze, Turkey
    Appl Biochem Biotechnol 160:856-67. 2010
    ..PVF) was used as a mediator for the fabrication of a horseradish peroxidase (HRP)-modified electrode to detect phenol derivatives via a composite polymeric matrix of conducting polypyrrole (PPy)...
  69. pmc Transcriptome analysis of a phenol-producing Pseudomonas putida S12 construct: genetic and physiological basis for improved production
    Nick J P Wierckx
    TNO Quality of Life, P O Box 5057, 2600 GB, Delft, The Netherlands
    J Bacteriol 190:2822-30. 2008
    The unknown genetic basis for improved phenol production by a recombinant Pseudomonas putida S12 derivative bearing the tpl (tyrosine-phenol lyase) gene was investigated via comparative transcriptomics, nucleotide sequence analysis, and ..
  70. ncbi Adsorption of phenol on a novel adsorption material PEI/SiO2
    Fuqiang An
    Department of Chemical Engineering, North University of China, Taiyuan 030051, People s Republic of China
    J Hazard Mater 152:1186-91. 2008
    ..trimethoxysilane (CP), and the novel adsorption material PEI/SiO2 with strong adsorption ability for phenol was prepared. The adsorption properties of PEI/SiO2 for phenol were researched by both static and dynamic methods...
  71. ncbi Optimization of phenol degradation by Candida tropicalis Z-04 using Plackett-Burman design and response surface methodology
    Jiangya Zhou
    School of Environmental Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, Shanghai 200240, China
    J Environ Sci (China) 23:22-30. 2011
    Statistical experimental designs were used to optimize the process of phenol degradation by Candida tropicalis Z-04, isolated from phenol-degrading aerobic granules. The most important factors influencing phenol degradation (p < 0...
  72. ncbi Determination of the kinetic parameters of the phenol-degrading thermophile Bacillus themoleovorans sp. A2
    H Feitkenhauer
    Laboratory of Chemical Engineering and Industrial Chemistry, ETH Zürich Hönggerberg HCI, Zurich, Switzerland
    Appl Microbiol Biotechnol 57:744-50. 2001
    ..g. from crude oil refineries, coal gasification plants or olive oil mills. Phenol removal is a key process for the biodegradation of pollutants at high temperatures because even low concentrations ..
  73. ncbi Intergeneric coaggregation of strains isolated from phenol-degrading aerobic granules
    Sunil S Adav
    Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
    Appl Microbiol Biotechnol 79:657-61. 2008
    ..I2 or Candida tropicalis I9 (with GenBank accession numbers EU250016, EU036759, and DQ515822) isolated from phenol-degrading aerobic granules...
  74. ncbi The isolation and analysis of phenol-soluble modulins of Staphylococcus epidermidis
    Hwang Soo Joo
    Pathogen Molecular Genetics Section, Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, U S National Institutes of Health, Bethesda, MD, USA
    Methods Mol Biol 1106:93-100. 2014
    b>Phenol-soluble modulins (PSMs) are multifunctional peptide toxins produced by many staphylococcal strains. PSMs have received much recent attention, owing to multiple reports underscoring their importance for staphylococcal pathogenesis...
  75. ncbi Internal mass transfer effect on biodegradation of phenol by Ca-alginate immobilized Ralstonia eutropha
    Arzu Y Dursun
    Department of Environmental Engineering, Firat University, 23100 Elazig, Turkey
    J Hazard Mater 126:105-11. 2005
    b>Phenol biodegradation by free and Ca-alginate immobilized Ralstonia eutropha was performed in batch system...
  76. ncbi Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 revealed by quantitative proteomics
    Pedro M Santos
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisboa, Portugal
    OMICS 11:233-51. 2007
    Quantitative proteomics was used to gain insights into the global adaptive response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 when an alternative carbon source (pyruvate or succinate) is present...
  77. pmc The alkene monooxygenase from Xanthobacter strain Py2 is closely related to aromatic monooxygenases and catalyzes aromatic monohydroxylation of benzene, toluene, and phenol
    N Y Zhou
    Department of Biochemistry, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom
    Appl Environ Microbiol 65:1589-95. 1999
    ..Detailed comparison of XamoA with the oxygenase alpha-subunits from aromatic monooxygenases, phenol hydroxylases, methane monooxygenase, and the alkene monooxygenase from Rhodococcus rhodochrous B276 showed that, ..
  78. ncbi Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase
    Kohtaro Kirimura
    Department of Applied Chemistry, Faculty of Science and Engineering, Waseda University, 3 4 1 Ohkubo, Shinjuku ku 169 8555, Tokyo, Japan
    Biochem Biophys Res Commun 394:279-84. 2010
    Salicylic acid decarboxylase (Sdc) can produce salicylic acid from phenol; it was found in the yeast Trichosporon moniliiforme WU-0401 and was for the first time enzymatically characterized, with the sdc gene heterologously expressed...
  79. ncbi Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure
    Y Panahi
    Department of Chemical Injury, Baqyatallah Hospital, Tehran, Iran
    Singapore Med J 48:392-5. 2007
    ..The current study evaluated the efficacy of a combination of one percent phenol and one percent menthol in the control of pruritus in these affected patients.
  80. ncbi Microorganisms involved in anaerobic phenol degradation in the treatment of synthetic coke-oven wastewater detected by RNA stable-isotope probing
    Kazuo Sueoka
    Institute of Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan
    FEMS Microbiol Lett 291:169-74. 2009
    An RNA-based stable-isotope probing method was used to identify anaerobic phenol-assimilating bacteria present in activated sludge and used to treat synthetic coke-oven wastewater...
  81. ncbi Regioselective nitration of phenol induced by catalytic antibodies
    Remy Ricoux
    Laboratoire de Chimie Bioorganique et Bioinorganique, FRE 2127 CNRS, Institut de Chimie Moléculaire d Orsay, Bat 420, Universite de Paris Sud XI, 91405, Orsay Cedex, France
    J Protein Chem 21:473-7. 2002
    ..This paper shows that those complexes also catalyzed efficiently the nitration of phenol into 2- and 4-nitrophenol by NO2- in the presence of H2O2...
  82. pmc Phenylphosphate carboxylase: a new C-C lyase involved in anaerobic phenol metabolism in Thauera aromatica
    Karola Schühle
    Mikrobiologie, Institut Biologie II, Universitat Freiburg, Germany
    J Bacteriol 186:4556-67. 2004
    The anaerobic metabolism of phenol in the beta-proteobacterium Thauera aromatica proceeds via carboxylation to 4-hydroxybenzoate and is initiated by the ATP-dependent conversion of phenol to phenylphosphate...
  83. ncbi Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds
    Andrew M Jenner
    Biochemistry Department, Faculty of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597
    Free Radic Biol Med 38:763-72. 2005
    ..This study is the first to measure the range of aromatic compounds in human fecal water and demonstrates that phenolic acid concentrations are high. The biological effects of phenolics may play an important role in colon function...
  84. ncbi Rhodococcus phenolicus sp. nov., a novel bioprocessor isolated actinomycete with the ability to degrade chlorobenzene, dichlorobenzene and phenol as sole carbon sources
    Marc Rehfuss
    Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Syst Appl Microbiol 28:695-701. 2005
    The aerobic degradation of phenol, chlorobenzene and dichlorobenzene as a sole carbon source has been observed in bacterial Gram-positive strain G2PT isolated from a wastewater bioprocessor...
  85. pmc Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600
    V Shingler
    Unit for Applied Cell and Molecular Biology, University of Umea, Sweden
    J Bacteriol 174:711-24. 1992
    ..Pseudomonas sp. strain CF600 grows efficiently on phenol, cresols, and 3,4-dimethylphenol via a plasmid-encoded multicomponent phenol hydroxylase and a subsequent meta-..
  86. ncbi Comparison of different advanced oxidation processes for phenol degradation
    Santiago Esplugas
    Departamento de Ingenieria Química y Metalurgia de la Universidad de Barcelona, Spain
    Water Res 36:1034-42. 2002
    ..Processes (O3, O3/H2O2, UV, UV/O3, UV/H2O2, O3/UV/H2O2, Fe2+ /H2O2 and photocatalysis) for degradation of phenol in aqueous solution have been studied in earlier works...
  87. ncbi Evolution of toxicity upon wet catalytic oxidation of phenol
    A Santos
    Departamento de Ingenieria Quimica, Facultad de Ciences Químicas, Universidad Complutense de Madrid, Cuidad Universitaria s n 28040, Madrid, Spain
    Environ Sci Technol 38:133-8. 2004
    This work reports on the evolution of the toxicity of phenol-containing simulated wastewater upon catalytic wet oxidation with a commercial copper-based catalyst (Engelhard Cu-0203T)...
  88. ncbi Study of phenol biodegradation using Bacillus amyloliquefaciens strain WJDB-1 immobilized in alginate-chitosan-alginate (ACA) microcapsules by electrochemical method
    Daban Lu
    Department of Chemistry, Lanzhou University, Lanzhou, 730000, People s Republic of China
    Biodegradation 23:209-19. 2012
    An aerobic microorganism with an ability to utilize phenol as sole carbon and energy source was isolated from phenol-contaminated wastewater samples...
  89. ncbi Integrated photocatalytic-biological reactor for accelerated phenol mineralization
    Yongming Zhang
    Department of Environmental Engineering, College of Life and Environmental Science, Shanghai Normal University, Shanghai, 200234, People s Republic of China
    Appl Microbiol Biotechnol 86:1977-85. 2010
    An integrated photocatalytic-biological reactor (IPBR) was developed for accelerated phenol degradation and mineralization...
  90. ncbi Bacterial degradation of airborne phenol in the phyllosphere
    Amarjyoti Sandhu
    Department of Plant Pathology and Interdepartmental Microbiology Program, Iowa State University, Ames, IA 50011 3211, USA
    Environ Microbiol 9:383-92. 2007
    ..Here, we examined bacterial acquisition and degradation of phenol on leaves by an introduced phenol degrader and by natural phyllosphere communities...
  91. ncbi Enhancement of phenol degradation by soil bioaugmentation with Pseudomonas sp. JS150
    A Mrozik
    Department of Biochemistry, University of Silesia, Jagiellonska 28, Katowice, Poland
    J Appl Microbiol 111:1357-70. 2011
    To test whether bioaugmentation with genetically modified Pseudomonas sp. JS150 strain could be used to enhance phenol degradation in contaminated soils.
  92. ncbi Influence of phenol on the biodegradation of pyridine by freely suspended and immobilized Pseudomonas putida MK1
    M K Kim
    Environmental and Molecular Microbiology Laboratory, Department of Biological Sciences, Korea Advanced Institute of Science and Technology KAIST, Daejeon, Korea
    Lett Appl Microbiol 42:495-500. 2006
    To study the effect of co-contaminants (phenol) on the biodegradation of pyridine by freely suspended and calcium alginate immobilized bacteria.
  93. ncbi Sonographically guided phenol injection in painful stump neuroma
    Hannes Gruber
    Department of Radiodiagnostics, University Hospital Innsbruck, Anichstrasse 35, Innsbruck 6020, Austria
    AJR Am J Roentgenol 182:952-4. 2004
  94. ncbi Adsorption and recognizing ability of molecular imprinted polymer MIP-PEI/SiO(2) towards phenol
    Fuqiang An
    Department of Chemical Engineering, North University of China, Taiyuan, PR China
    J Hazard Mater 157:286-92. 2008
    ..imprinting was carried out towards the macromolecule PEI grafted on the surface of silica particles using phenol as a template and diepoxyalkyl (669) as a crosslinking agent...
  95. ncbi Remediation of phenol-contaminated soil by a bacterial consortium and Acinetobacter calcoaceticus isolated from an industrial wastewater treatment plant
    S M Cordova-Rosa
    Universidade do Vale do Itajai, Centro de Ciências Tecnológicas da Terra e do Mar, 88302 202, Itajai, SC, Brazil
    J Hazard Mater 164:61-6. 2009
    Time-course performance of a phenol-degrading indigenous bacterial consortium, and of Acinetobacter calcoaceticus var. anitratus, isolated from an industrial coal wastewater treatment plant was evaluated...
  96. ncbi Automatic biodetector of water toxicity (ABTOW) as a tool for examination of phenol and cyanide contaminated water
    Andrzej Woznica
    Department of Biochemistry, Faculty of Biology and Environmental Protection, University of Silesia, 40 032 Katowice, Poland
    Chemosphere 81:767-72. 2010
    ..The dynamics of ABTOW response is studied in details for phenol and cyanide as model toxins. These data indicate that the sensitivity was 3.5 μM for phenol and 0...
  97. ncbi Photocatalytic degradation of phenol
    Feryal Akbal
    Ondokuz Mayis University, Faculty of Engineering, Environmental Engineering Department, Kurupelit Samsun, Turkey
    Environ Monit Assess 83:295-302. 2003
    In this study photocatalytic degradation of phenol in the presence of UV irradiated TiO2 catalyst and H2O2 was investigated. Effects of TiO2 and H2O2 concentrations and pH on photocatalytic degradation were examined...
  98. ncbi Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp strain ST-550 in a water-organic solvent two-phase system
    N Doukyu
    Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8501, Japan
    Appl Microbiol Biotechnol 60:720-5. 2003
    ..One of the proteins showed a N-terminal amino acid sequence that was identical to that of the largest subunit of phenol hydroxylase (MopN) from A. calcoaceticus NCBI8250...
  99. ncbi Combined biological and photocatalytic treatment for the mineralization of phenol in water
    Dhanus Suryaman
    Department of Chemical and Biochemical Engineering, Faculty of Engineering, Toyama University, 3190 Gofuku, Toyama 930 8555, Japan
    Chemosphere 65:2502-6. 2006
    b>Phenol is degraded by biological treatment, however mineralization requires long time...
  100. ncbi Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin
    N A Monteiro-Riviere
    Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA
    Toxicol Ind Health 17:95-104. 2001
    Pure phenol is colorless and used in the manufacture of phenolic resins, plastics, explosives, fertilizers, paints, rubber, textiles, adhesives, pharmaceuticals, paper, soap, and wood preservatives...
  101. ncbi Characterization of phenol and trichloroethene degradation by the rhizobium Ralstonia taiwanensis
    Wen Ming Chen
    Department of Seafood Science, National Kaohsiung Marine University, Nan Tzu, Kaohsiung City 811, Hai Chuan Rd No 142, Taiwan
    Res Microbiol 155:672-80. 2004 southern Taiwan. Some strains of R. taiwanensis demonstrated the ability to grow on medium containing phenol as the sole carbon source, especially strain TJ86, which was able to survive and grow at phenol concentrations of ..

Research Grants66

    JENNY GLUSKER; Fiscal Year: 2002
    ..Some ab initio molecular orbital studies of reaction pathways in the metabolism of benzene and phenol will also be carried out...
    Robert Phillips; Fiscal Year: 2004
    ..These enzymes include tryptophan indole-lyase, tyrosine phenol-lyase, tryptophan synthase, bacterial and human kynureninases, and aspartate beta-decarboxylase...
  3. Enhanced Membrane Systems for Supplying Quality Drinking Water
    Andrew Feiring; Fiscal Year: 2013
    ..Poliovirus, Cryptosporidium parvum, Legionelle pneumophila, and Salmonella enterica plus specific chemicals, phenol, and humic acid), Cryptosporidium or appropriate surrogate...
  4. Genome-wide measurement of bacterial transcriptional regulatory states
    Peter L Freddolino; Fiscal Year: 2013
    ..from crosslinked lysates, using the fact that these complexes partition to the organic-aqueous interphase during phenol-chloroform extraction. High throughput sequencing is used to reveal the locations of DNA-bound TFs...
  5. Tyrosinase Model Complexes using Imidazole Ligands
    JOHN BRANNON GARY; Fiscal Year: 2013
    ..a substrate-binding induced rearrangement to an isomeric bis-m-oxo-dicopper(III) intermediate (O) that performs phenol oxidation with electronic and kinetic isotope parameters consistent with enzymatic values...
  6. Green tea effects on gene expression in tobacco users
    Joel L Schwartz; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Green tea (GT) is a mixture largely of catechins, which are phenol flavonoids, and caffeine, that has shown efficacy in preventing lung cancer and a large host of other spontaneous and experimentally ..
  7. Octopamine Neuroanatomy and Functioning in Fruit Fly Social Behavior
    KYLE LYNN GOBROGGE; Fiscal Year: 2013
    ..Interestingly, the phenol analogue of norepinephrine - octopamine (OA), which is commonly found in invertebrate species, was recently found ..
  8. Hormonal Modulation of Aggression in Drosophila
    Edward A Kravitz; Fiscal Year: 2013
    ..These studies focus on two major amines found in the fruit fly nervous system: octopamine (OA), the phenol analogue of norepinephrine, is the major amine synthesized from tyrosine;and serotonin (5HT), is the major amine ..
  9. Epitope-specific vaccines targeting the alpha toxin of Staphylococcus aureus
    KEMP BAILEY CEASE; Fiscal Year: 2013
    ..aureus infections. The goal of this project is to develop epitope-specific vaccines targeting alpha toxin and the phenol-soluble modulins (PSMs), which are two critical virulence factors for S. aureus, for use in preventing S...
  10. Coupled Transfers of Electrons and Protons
    James M Mayer; Fiscal Year: 2013
    ..The phenol studies, for instance, will shed light on the formation of tyrosyl radicals in enzymatic catalysis or under ..
  11. Heme/Copper and Heme/Nonheme Iron O(2) and NO Reactivity
    Kenneth D Karlin; Fiscal Year: 2013
    ..or biochemical systems, (3) the employment and study of ligand systems which possess a copper-ligand imidazole-phenol moiety which induces O-O reductive cleavage chemistry for a corresponding heme/copper-O2 assembly...
  12. Design and synthesis of novel anticonvulsant molecules.
    Rajesh Kumar Mishra; Fiscal Year: 2011
    ..Propofol and this novel analog, 2,6-diisopropyl-4-(1-hydroxy-2,2,2-trifluoroethyl)phenol (MB003), both exhibit lower ED50s than many other anti-convulsant drugs including valproic acid, felbamate, ..
  13. Peri-Conceptional Biomonitoring
    Christina Porucznik; Fiscal Year: 2013
    ..SPECIFIC AIMS 1. Conduct prospective, peri-ovulational biomonitoring for disinfection by-products (DBP) and bis-phenol-A (BPA) in a human preconception cohort using a novel strategy of self-collection of environmental and biological ..
  14. Mechanisms of PVL-induced Acute Lung Injury
    Binh An Diep; Fiscal Year: 2013
    ..Aim 3. To determine the relative effects of PVL, -hemolysin (HLA), and -type phenol-soluble modulins (PSM-) on acute lung injury and necrotizing pneumonia in the rabbit model...
  15. Understanding protein radicals
    Cecilia Tommos; Fiscal Year: 2012
    ..During the proposed five-year funding period, we will structurally characterize the reduced and oxidized states of phenol-labeled proteins whose redox properties have already been determined by voltammetry techniques...
  16. Silk Fibroin Small-Molecule Drug Carriers for the Treatment of Osteoarthritis
    TIMOTHY KARIITHI MWANGI; Fiscal Year: 2013
    ..Curcumin is a small di-phenol that inhibits inflammation in many cell types and will be used as a model drug here...
  17. Mechanisms of Reduced Heart Failure Pathogenesis with Phytochemical Intake
    Steven F Bolling; Fiscal Year: 2012
    ..Phytochemicals can activate the NF-E2 p45-related factor (Nrf2) and the phenol-responsive Aryl-hydrocarbon receptor (AhR) which stimulates the gene transcription related to antioxidant defense...
  18. Identification of Novel Broad Spectrum Influenza Virus Inhibitors
    Arnab Basu; Fiscal Year: 2013
    ..g., endosomal pH, or sialic acid residues or viral/cell membrane). MBX494, MBX994, and MBX726 have aminoalkyl phenol ether, aminoacetamide sulfonamide and simple sulfonamide scaffolds respectively...
  19. Selective Opioid Antagonists as Medications for Drug Abuse
    Frank Ivy Carroll; Fiscal Year: 2013
    ..phenyl)morphan, (c) 4a-(3-hydroxyphenyl)-8a-methyldecahydroisoquinoline, (d) 3-[4-(substituted piperazin-1- yl)]phenol, and (e) N-substituted 4-(3-hydroxyphenyl)-4-methylazabicyclo[3.1.0]hexane classes of opioid antagonist...
  20. Targetting InhA For Anti-TB Drug Discovery
    Peter Tonge; Fiscal Year: 2009
    ..The lead compound for inhibitor discovery is triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol), a compound that inhibits InhA with a Ki value of 0.22 mu/M and which has an MIC99 for MTB of 5 mu/g/mL (17 mu/M)...
  21. Evaluating Aspects of O2-Activation by Bacterial Multicomponent Monooxygenases
    RACHEL BEHAN WOLLACOTT; Fiscal Year: 2010
    ..With the help of the recent crystal structure of phenol hydroxylase (PHH) and its regulatory protein (PHM) we have proposed several mutations to address these issues...
  22. The effect of curcumin on age-related cognitive decline in the rhesus monkey
    MARK BARRY MOSS; Fiscal Year: 2013
    ..Toward this evolving hypothesis, Curcumin, a natural phenol and member of the ginger family, has been shown to evidence such positive effects and provide a strong rationale ..
  23. Phase II Environmentally greener, efficient, and safe synthetic platform for the
    PAUL MATTHEW HERRINTON; Fiscal Year: 2011
    ..3. Augment the phenol portfolio to make more previously unreported products available. Increase the scale to produce kilogram quantities...
    Curtis Klaassen; Fiscal Year: 2003
    ..Both rats and humans are known to have seven major sulfotransferases. Rats have four phenol-sulfotransferases and three hydroxysteroid sulfotransferases, whereas humans have six phenol sulfotransferases and ..
  25. Palladium-Catalyzed Aerobic Dehydrogenation of Carbon-Carbon Bonds
    Shannon S Stahl; Fiscal Year: 2013
    ..are targeted: (1) dehydrogenation of cyclohexanones and cyclohexenones to prepare a variety of substituted phenol derivatives, (2) dehydrogenation of ketones and other carbonyl compounds to prepare versatile 1,2-unsaturated ..
  26. Biocatalytic Use of Cytochrome P450 Enzymes
    SHEEL DODANI; Fiscal Year: 2013
    ..this proposal are to: (1) Develop and evolve existing BM3 variants to utilize reactive nitrogen species to nitrate phenol, (2) Optimize the regioselectivity, product distribution, and substrate scope of BM3 mediated nitration, (3) ..
  27. Mixed Kappa-Mu Opioids: Synthesis and Evaluation
    John L Neumeyer; Fiscal Year: 2012
    ..1) Synthesis of morphinans with aminothiazole substitution of the phenol moiety in opioids...
  28. The Synthesis and Application of Novel Aromatic Materials
    THOMAS R PETTUS; Fiscal Year: 2012
    ..led to the development of other methods including novel procedures for o-quinone formation, enone epoxidation, and phenol dearomatization...
    George Jackson; Fiscal Year: 2009
    ..the technology by integrating it with currently available processing methods like guanidinium thiocyanate-phenol-chloroform (TRIzol) extraction of RNA/DNA...
    PAUL BLATZ; Fiscal Year: 1990
    ..Some of the experimental variables to be studied are: i) donor reagents such as phenol, substituted phenols, acetic acid and chloro substituted acetic acids, ii) selected solvents such as hydrocarbons ..
  31. New Chiral Br??nsted Acids for Asymmetric Synthesis
    WILLIAM DEAN WULFF; Fiscal Year: 2013
    ..fact that it can be assembled by the substrate from the ligand, a boron source, two equivalents of an alcohol or phenol and three equivalents of water...
  32. Structure and Mechanisms of PLP Dependent Lyases
    Robert Phillips; Fiscal Year: 2006
    ..The carbon-carbon lyase, tyrosine phenol-lyase (EC 4.1.99...
  33. Understanding coupled transfers of electrons and protons relevant to biological c
    James Mayer; Fiscal Year: 2007
    ..For example, the proposed studies of oxidation of phenol-base compounds will probe how framework motions affect hydrogen transfers, an issue of much current debate ..
  34. Search for the Molecular Targets of Phenols
    CYNTHIA SELASSIE; Fiscal Year: 2006
    ..potentials in vitro, in order to delineate which apoptotic pathway (intrinsic or extrinsic) is compromised in phenol exposed cells...
    Eckard Munck; Fiscal Year: 2002
    ..of the diiron proteins methane monooxygenase, ribonucleotide reductase, delta9 desaturase, toluene monooxygenase, phenol hydroxylase and alkane hydroxylase will be continued with particular focus on characterizing the electronic ..
    ..This route to phenols may be the major mode of phenol formation for many aromatic compounds whose metabolism involve the reaction of oxides with glutathione...
    Thomas Walle; Fiscal Year: 1999
    ..Aim 1 will investigate the structure-activity relationship and kinetics for inhibition of human P form phenol-ST (P-PST) and dehydroepiandrosterone-ST (DHEA-ST) by flavonoids, using recombinant enzymes, model substrates for ..
    Guangping Chen; Fiscal Year: 2003
    ..probes to identify amino acid residues in both the substrate- binding site and PAPS binding site of human liver phenol- sulfating ST (P-PST-1), dehydroepiandrosterone ST (DHEA-ST), and estrogen ST (EST). 2...
    STEVEN BOXER; Fiscal Year: 2003
    ..histidine in Mb with a very wide range of small organic ligands including methyl-substituted imidazoles, pyridine, phenol, furan, thiophene, and ethanethiol. With this method it is possible to radically alter the properties of Mb...
    TERRENCE MONKS; Fiscal Year: 2004
    ..Coadministration of hydroquinone (HQ) and phenol (PHE), however, does lead to bone marrow suppression in rodents...
    Martin Klinger; Fiscal Year: 1991
    ..We intend to evaluate these membranes on the basis of their ability to enzymatically convert phenol to the nontoxic product, phenylglucuronide...
  42. Innovative molecular cytogenetic techniques for early leukemia/lymphoma detection
    JOE LUCAS; Fiscal Year: 2005
    ..The method includes subtracting hybridized biotin-labeled repetitive-sequence DNA complex with phenol and chloroform and a second subtraction using avidin labeled magnetic beads...
    RUTH BILLINGS; Fiscal Year: 1990 conducted with purified isozymes of liver microsomal cytochrome P-450, to resolve which isozymes hydroxylate phenol metabolites to catechols...
    Michael Dunn; Fiscal Year: 1992
    ..e) What hexamer conformation states are induced in solution by the lyotropic anions (SCN- ,l-,Br-, Cl-) and by phenol? (f) How are the energetics of the phenol and lyotropic anion-induced conformational transitions influenced by ..
    DANIEL LUCHTEL; Fiscal Year: 1993
    ..vapors generated prior to polymerization of ACMs will be studied first in a relatively simple two-component (phenol-formaldehyde) model system, than as more complex multi-component mixtures...
  46. The Role of Quinols in Estrogen Neuroprotection
    Laszlo Prokai; Fiscal Year: 2006
    ..The phenol to quinol pathway may augment the estrogens' free-radical scavenging efficacy, and make a pivotal ..
    John Thompson; Fiscal Year: 2007
    ..lines derived from mouse lung epithelia and the tumorigenic siblings, polyclonal antibodies that recognize the phenol group, and a variety of mass spectrometric techniques...
  48. Pd-Catalyzed Olefin Functionalization Reactions for Organic Synthesis
    MATTHEW SIGMAN; Fiscal Year: 2007
    ..and develop our recently discovered Pd-catalyzed aerobic hydroalkoxylation reactions of styrenes containing a phenol, (2) develop and investigate Pd-catalyzed hydroalkoxylation reactions of styrene derivatives, (3) explore Pd-..
  49. Catalytic Asymmetric Synthesis of Vinyl Chromans Using Palladium(II) Catalysts
    ANGELA CHRISTINE OLSON; Fiscal Year: 2010
    ..The SN2'allylic substitution chemistry of trichloroacetimidates using a tethered phenol nucleophile will be examined using chiral cobalt oxazoline palladium(ll) catalysts...
    PATRICIA GWIRTZ; Fiscal Year: 1993
    ..10 will use conscious dogs and will examine whether chronic chemical sympathectomy [by topical application of phenol] exerts the same influence on the coronary collateral circulation as does surgical sympathectomy...
    THOMAS DOOLEY; Fiscal Year: 2001
    ..Three of the genes cloned and mapped by the applicant and his coworkers encode the phenol sulfotransferase gene loci, STP1, STP2, and STM...
    KAREN SPRAGUE; Fiscal Year: 1993
    ..Factor X appears to be a nucleic acid because it is resistant to heat, detergent, phenol, and protease, but sensitive to nuclease...
  53. Oxidative Stress, Antioxidants and Breast Cancer Risk
    Qi Dai; Fiscal Year: 2007
    ..5% cohort members. For this proposed study, urinary level of total phenols will be assayed with Folin-Ciocalteu Phenol Reagent, urinary levels of polyphenol flavonols and flavanols will be determined using liquid chromatography photo-..
    Richard Weinshilboum; Fiscal Year: 1980 expand these studies to include two additional catecholamine metabolic enzymes, monoamine oxidase (MAO) and phenol sulphotransferase (PST). Inhibitors of MAO have been used clinically as antihypertensive agents...
    Kelly Nichols; Fiscal Year: 2003
    ..the additional diagnostic tests performed in the dry eye examination (osmolality, lactoferrin concentration, phenol red thread test, and lissamine green conjunctival staining) and our proposed definition of dry eye...
    Michael Apicella; Fiscal Year: 1980
    ..which is based on a family of acidic polysaccharides designated Gc antigens which can be isolated from the phenol-water extract by DEAE chromatography...
    ANTON LEWIS USALA; Fiscal Year: 2000
    ..Surgical interruption of the skin vasculature, or phenol chemical burns, will be induced at six separate sites in two cohorts of four pigs each...
    Clifford Weisel; Fiscal Year: 2000
    ..the fraction of total inhaled benzene by humans excreted as ring hydroxylated metabolites, hydroquinone, and phenol, ring opened metabolite, trans, trans muconic acid, and unmetabolized benzene by human subjects following exposure ..
    Brian Thomas; Fiscal Year: 2001
    ..probing the putative antagonist conferring interaction, analogs of the pyran oxygen interaction and pyrazole / phenol correspondence analogs...
    Vaughn Smider; Fiscal Year: 2002
    ..Tyrosine depletion can be accomplished by dietary restriction or through catabolism by the enzyme tyrosine phenol-lyase (TPL)...
  61. Synthesis through N-Acylnitrenium Ion Cyclization
    DUNCAN WARDROP; Fiscal Year: 2006
    ..6]azaspiranes. The dienone-phenol rearrangement of this ring system will be studied since it will provide rapid access to the benzazocine core of ..
    SARAH THURSTON; Fiscal Year: 2004
    ..Genotyping for multiple genes is ongoing. Phenol-related adducts have been measured in nontumorous lung tissue for 69 cases and in mononuclear blood cells for 38 ..
    Robert Phillips; Fiscal Year: 2000
    ..renewal application to provide continued support for collaborative studies on the enzymatic mechanisms of tyrosine phenol-lyase...
    Michael Lovett; Fiscal Year: 2009
    ..Most investigators would prefer this to be simplified and standardized into a "kit-like" format. We shall test phenol emulsion methods to increase nucleic acid reassociation rates and to standardize the selection parameters...
    Philip Loverde; Fiscal Year: 1991
    ..reproduction by stimulating vitelline gland development, the focus will be on vitellaria-specific genes such as phenol oxidase...
    THEODORE MILL; Fiscal Year: 1980
    ..Vitamin E is a less efficient radical trap than BHT in liposomes and the products of phenol oxidation in liposomes are different from those in solution...