chlorinated hydrocarbons

Summary

Top Publications

  1. ncbi A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002
    Duk Hee Lee
    Department of Preventive Medicine, School of Medicine, Kyungpook University, 101 Dongin dong, Jung Gu, Daegu, Korea 700 422
    Diabetes Care 29:1638-44. 2006
  2. ncbi Increased plasma levels of toxic pollutants accompanying weight loss induced by hypocaloric diet or by bariatric surgery
    Olivier Hue
    Department of Social and Preventive Medicine, Laval University, Quebec, Canada
    Obes Surg 16:1145-54. 2006
  3. ncbi Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002
    Duk Hee Lee
    Department of Preventive Medicine, School of Medicine, Kyungpook National University, 101 Dongin dong, Jung Gu, Daegu, Korea 700 422
    Diabetes Care 30:622-8. 2007
  4. ncbi Geographical distribution of organochlorine pesticides (OCPs) in polar bears (Ursus maritimus) in the Norwegian and Russian Arctic
    E Lie
    National Veterinary Institute, PO Box 8156 Dep, Oslo N 0033, Norway
    Sci Total Environ 306:159-70. 2003
  5. ncbi Environmental and lifestyle factors for organochlorine exposure among women living in Southern Spain
    I Cerrillo
    Laboratory of Medical Investigations, School of Medicine, University of Granada, Hospital Clinico, 18071 Granada, Spain
    Chemosphere 62:1917-24. 2006
  6. ncbi Plasma organochlorine concentrations in endurance athletes and obese individuals
    Catherine Pelletier
    Physical Activity Sciences Laboratory and Division of Kinesiology, PEPS and Department of Food Science and Nutrition, Laval University, Ste Foy Québec, Canada
    Med Sci Sports Exerc 34:1971-5. 2002
  7. ncbi Burden of organochlorine pesticides in blood and its effect on thyroid hormones in women
    Minakshi Rathore
    Department of Zoology, University of Rajasthan, Jaipur, India
    Sci Total Environ 295:207-15. 2002
  8. ncbi Kinetic models for volatile chlorinated hydrocarbons removal by zero-valent iron
    Václav Janda
    Department of Water Technology and Environmental Engineering, Institute of Chemical Technology Prague, Technicka 5, CZ 166 28 Prague 6, Czech Republic
    Chemosphere 54:917-25. 2004
  9. ncbi Prenatal organochlorine pesticides in placentas from Finland: exposure of male infants born during 1997-2001
    H Shen
    Placenta 26:512-4. 2005
  10. ncbi Body burdens and tissue concentrations of organochlorines in polar bears (Ursus maritimus) vary during seasonal fasts
    S C Polischu
    Office of the Vice President Research, University of Saskatchewan, Saskatoon, Canada
    Environ Pollut 118:29-39. 2002

Detail Information

Publications206 found, 100 shown here

  1. ncbi A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002
    Duk Hee Lee
    Department of Preventive Medicine, School of Medicine, Kyungpook University, 101 Dongin dong, Jung Gu, Daegu, Korea 700 422
    Diabetes Care 29:1638-44. 2006
    ..Low-level exposure to some persistent organic pollutants (POPs) has recently become a focus because of their possible link with the risk of diabetes...
  2. ncbi Increased plasma levels of toxic pollutants accompanying weight loss induced by hypocaloric diet or by bariatric surgery
    Olivier Hue
    Department of Social and Preventive Medicine, Laval University, Quebec, Canada
    Obes Surg 16:1145-54. 2006
    ....
  3. ncbi Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002
    Duk Hee Lee
    Department of Preventive Medicine, School of Medicine, Kyungpook National University, 101 Dongin dong, Jung Gu, Daegu, Korea 700 422
    Diabetes Care 30:622-8. 2007
    ..S population with background exposure to POPs. Here, we investigated POPs and insulin resistance, a frequent pathogenic precursor of type 2 diabetes...
  4. ncbi Geographical distribution of organochlorine pesticides (OCPs) in polar bears (Ursus maritimus) in the Norwegian and Russian Arctic
    E Lie
    National Veterinary Institute, PO Box 8156 Dep, Oslo N 0033, Norway
    Sci Total Environ 306:159-70. 2003
    ..This may imply the presence of a significant pollution source in the Russian Arctic area. The study suggests that the western Russian Arctic is the most contaminated region of the Arctic and warrants further research...
  5. ncbi Environmental and lifestyle factors for organochlorine exposure among women living in Southern Spain
    I Cerrillo
    Laboratory of Medical Investigations, School of Medicine, University of Granada, Hospital Clinico, 18071 Granada, Spain
    Chemosphere 62:1917-24. 2006
    ..Research is required on women occupationally exposed to a selected group of organochlorine pesticides, especially those of reproductive age, as a basis for preventive action...
  6. ncbi Plasma organochlorine concentrations in endurance athletes and obese individuals
    Catherine Pelletier
    Physical Activity Sciences Laboratory and Division of Kinesiology, PEPS and Department of Food Science and Nutrition, Laval University, Ste Foy Québec, Canada
    Med Sci Sports Exerc 34:1971-5. 2002
    ..Their plasma concentrations were compared in three groups of individuals with different body fatness characteristics: endurance athletes, lean sedentary subjects, and obese individuals...
  7. ncbi Burden of organochlorine pesticides in blood and its effect on thyroid hormones in women
    Minakshi Rathore
    Department of Zoology, University of Rajasthan, Jaipur, India
    Sci Total Environ 295:207-15. 2002
    ..The correlation analysis for dieldrin and depleted T4 levels in hypothyroid women elicited an inverse relationship between them...
  8. ncbi Kinetic models for volatile chlorinated hydrocarbons removal by zero-valent iron
    Václav Janda
    Department of Water Technology and Environmental Engineering, Institute of Chemical Technology Prague, Technicka 5, CZ 166 28 Prague 6, Czech Republic
    Chemosphere 54:917-25. 2004
    ..Regression analysis proved, that the first-order kinetic is not suitable for the modelling of chlorinated hydrocarbons dechlorination...
  9. ncbi Prenatal organochlorine pesticides in placentas from Finland: exposure of male infants born during 1997-2001
    H Shen
    Placenta 26:512-4. 2005
  10. ncbi Body burdens and tissue concentrations of organochlorines in polar bears (Ursus maritimus) vary during seasonal fasts
    S C Polischu
    Office of the Vice President Research, University of Saskatchewan, Saskatoon, Canada
    Environ Pollut 118:29-39. 2002
    ..Since developing young may be susceptible to the effects of environmental contaminants, the increased exposure of nursing cubs to OCs during a fast by their mothers is noteworthy...
  11. ncbi Strategies for the aerobic co-metabolism of chlorinated solvents
    L Semprini
    Department of Civil, Construction, and Environmental Engineering, Oregon State University, Corvallis 97331 2302, USA
    Curr Opin Biotechnol 8:296-308. 1997
    ..Many factors can enhance co-metabolic transformations, such as nutrients and available energy sources...
  12. ncbi Photodegradation of chlorinated hydrocarbons in the presence and absence of dissolved oxygen in water
    H Shirayama
    Water Pollution Section, Toyama Prefectural Environmental Science Research Center, Kosugi, Imizu gun, Toyama 939 0363, Japan
    Water Res 35:1941-50. 2001
    The photodegradation rates of seven chlorinated hydrocarbons; C2Cl4, C2HCl3, C2H4Cl2, 1,1,1-C2H3Cl3, 1,1,2-C2H3Cl3, CHCl3, CCl4 were investigated under the UV bandwidths of 185 and 254 nm in the presence and absence of dissolved oxygen (..
  13. ncbi Serum organochlorine levels and history of lactation in Egypt
    Amr S Soliman
    Department of Epidemiology, The University of Texas, M D Anderson Cancer Center, Box 189 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Environ Res 92:110-7. 2003
    ..Organochlorine serum level was not a risk factor of breast cancer in this population...
  14. ncbi Health of tree swallow (Tachycineta bicolor) nestlings exposed to chlorinated hydrocarbons in the St Lawrence River basin. Part I. Renal and hepatic vitamin A concentrations
    Barbara Martinovic
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1053-72. 2003
    ..Lower circulating levels and higher tissue concentrations of retinoids may result in compromised immune function and reduced reproductive success in adult birds...
  15. pmc Organochlorine exposure and incidence of diabetes in a cohort of Great Lakes sport fish consumers
    Mary Turyk
    Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago, Chicago, Illinois 60612, USA
    Environ Health Perspect 117:1076-82. 2009
    ..Prospective studies, however, have been lacking...
  16. ncbi Interactions of persistent environmental organohalogens with the thyroid hormone system: mechanisms and possible consequences for animal and human health
    A Brouwer
    Department of Toxicology, Wageningen Agricultural University, The Netherlands
    Toxicol Ind Health 14:59-84. 1998
    ....
  17. ncbi Global assessment of organic contaminants in farmed salmon
    Ronald A Hites
    School of Public and Environmental Affairs, Indiana University, Bloomington, IN 47405, USA
    Science 303:226-9. 2004
    ..Risk analysis indicates that consumption of farmed Atlantic salmon may pose health risks that detract from the beneficial effects of fish consumption...
  18. ncbi Organochlorines, p53 mutations in relation to breast cancer risk and survival. A Danish cohort-nested case-controls study
    Annette Pernille Høyer
    The Copenhagen Center for Prospective Population Studies, Denmark
    Breast Cancer Res Treat 71:59-65. 2002
    ..These preliminary results suggest that p53 mutations may have a modifying effect on at least the breast cancer risk associated with exposures to organochlorines...
  19. ncbi Toxicity of trans-nonachlor to Sprague-Dawley rats in a 90-day feeding study
    Genevieve Bondy
    Toxicology Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada, K1A 0L2
    Food Chem Toxicol 42:1015-27. 2004
    ..Differences in target organ responses in male and female rats indicate that the sex-related metabolic differences affecting trans-nonachlor bioaccumulation and elimination merit further study...
  20. ncbi Carry-over of persistent organochlorine pesticides through placenta to fetus
    S M Waliszewski
    Instituto de Medicina Forense de la Universidad Veracruzana, Veracruz, Ver, Mexico
    Salud Publica Mex 42:384-90. 2000
    ..To establish their distribution in the human body, the concentration gradients of organochlorine pesticides between these compartments were determined...
  21. ncbi Cancer incidence among workers potentially exposed to chlorinated solvents in an electronics factory
    Yung Ming Chang
    Graduate Institute of Life Sciences, National Defense Medical Center, National Defense University, Taiwan, Republic of China
    J Occup Health 47:171-80. 2005
    ..This study provides no evidence that exposure to chlorinated organic solvents at the electronics factory was associated with elevated human cancers. Dominant short-term employees may bias the cancer risk toward false positive...
  22. pmc Increased mortality odds ratio of male liver cancer in a community contaminated by chlorinated hydrocarbons in groundwater
    L J H Lee
    Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan
    Occup Environ Med 60:364-9. 2003
    To investigate the association between cancer mortality risk and exposure to chlorinated hydrocarbons in groundwater of a downstream community near a contaminated site.
  23. ncbi Organochlorines affect the steroid hormone cortisol in free-ranging polar bears (Ursus maritimus) at Svalbard, Norway
    Irma Oskam
    Department of Production Animal Clinical Science, Norwegian School of Veterinary Science, Oslo, Norway
    J Toxicol Environ Health A 67:959-77. 2004
    ..Despite the complexity on stress responses and the interactions with environmental factors, this study demonstrated that high concentrations of OCs in polar bears might alter plasma cortisol concentrations...
  24. pmc Risk of non-Hodgkin's lymphoma and prediagnostic serum organochlorines: beta-hexachlorocyclohexane, chlordane/heptachlor-related compounds, dieldrin, and hexachlorobenzene
    Kenneth P Cantor
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Environ Health Perspect 111:179-83. 2003
    ..These findings do not support the hypothesis that the organochlorine compounds included in this study are strongly linked to the development of NHL. The possibility of a weak association cannot be excluded by these data...
  25. ncbi Epidemiological evidence on reproductive effects of persistent organochlorines in humans
    Gunnar Toft
    Department of Occupational Medicine, Aarhus University Hospital, Noerrebrogade 44, Build 2C, 8000 Aarhus C, Denmark
    Reprod Toxicol 19:5-26. 2004
    ..Due to inherent methodological problems in several of the available studies, additional research is needed to fully elucidate the possible adverse effects of organochlorines on human reproductive health...
  26. ncbi Smoking as a determinant of high organochlorine levels in Greenland
    Bente Deutch
    Centre of Arctic Environmental Medicine, Aarhus University, Aarhus, Denmark
    Arch Environ Health 58:30-6. 2003
    ..These findings confirm that the source of POPs among the Inuit in Greenland is diet, but smoking is an important determinant of POP bioaccumulation. Smoking cessation may provide a means to lower the body burden of POPs...
  27. ncbi A proportionate cancer morbidity ratio study of workers exposed to chlorinated organic solvents in Taiwan
    Yung Ming Chang
    Graduate Institute of Life Sciences, National Defense Medical Center, 161 Ming Chun East Road, Sec 6, Nei Hu, Taipei, Taiwan, 114, ROC
    Ind Health 41:77-87. 2003
    ..Since this association has never been reported in the previous studies, further study is needed to clarify the association...
  28. ncbi Investigation of organochlorine pesticides (OCPs) in mollusks collected from coastal sites along the Chinese Bohai Sea from 2002 to 2004
    Yawei Wang
    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, P O Box 2871, 18 Shuangqing Road, Haidian District, Beijing 100085, China
    Environ Pollut 146:100-6. 2007
    ..Principal component analysis (PCA) was also used for determining the polluting characters existing in this selected field...
  29. ncbi Incidence of hospitalized osteoporotic fractures in cohorts with high dietary intake of persistent organochlorine compounds
    Ann Kathrine Alveblom
    Department of Occupational and Environmental Medicine, Lund University Hospital, 221 85 Lund, Sweden
    Int Arch Occup Environ Health 76:246-8. 2003
    ..The goal of this study was to assess whether a high dietary intake of POCs through fatty fish from the Baltic Sea may result in an increased incidence of osteoporotic fractures...
  30. ncbi Exposure of women to organochlorine pesticides in Southern Spain
    Begoña Botella
    Laboratory of Medical Investigations, Department of Radiology, School of Medicine, Hospital Clinico, University of Granada, 18071 Granada, Spain
    Environ Res 96:34-40. 2004
    ..Because many of these chemicals can mobilize during pregnancy and lactation, further research is warranted to interpret the health consequences for the children of such exposure...
  31. ncbi Organochlorine pesticides in seafood products from southern China and health risk assessment
    Jian yang Guo
    State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China
    Environ Toxicol Chem 26:1109-15. 2007
    ..Therefore, continual monitoring of OCPs in various environment compartments, including biota and abiota, urgently is needed to mitigate effectively the impact of OCPs, particularly DDTs, on human health and the ecological environment...
  32. pmc Organochlorine compounds and concentrations of thyroid stimulating hormone in newborns
    N Ribas-Fito
    Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Occup Environ Med 60:301-3. 2003
    ..To assess the association between prenatal exposure to organochlorine compounds and thyroid status in newborns from an area with high levels of hexachlorobenzene (HCB)...
  33. ncbi Predictors of organochlorines in New York City pregnant women, 1998-2001
    Mary S Wolff
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, 1 Gustave Levy Pl, Box 1057, New York, NY 10029 6574, USA
    Environ Res 97:170-7. 2005
    ..In multivariate models, levels of OCs increased with age; DDE was higher in women not born in the US or Puerto Rico; PCB were higher in women who bought fresh fish and lower in those with higher body mass indices...
  34. pmc Determinants of serum concentrations of organochlorine compounds in Swedish pregnant women: a cross-sectional study
    Anders Glynn
    Swedish National Food Administration, Uppsala, Sweden
    Environ Health 6:2. 2007
    ....
  35. ncbi Exposure to organochlorine compounds and effects on ovarian function
    Gayle C Windham
    Environmental Health Investigations Branch, Department of Health Services, Oakland, California 94612, USA
    Epidemiology 16:182-90. 2005
    ..Some chemicals appear to have hormonally active properties in animals, but data in humans are sparse. Therefore, we examined ovarian function in relation to organochlorine compound levels...
  36. pmc Inter-population variations in concentrations, determinants of and correlations between 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE): a cross-sectional study of 3161 men and women from Inuit and
    Bo A G Jonsson
    Department of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Environ Health 4:27. 2005
    ....
  37. ncbi PCBs and organochlorine pesticides (OCPs) in edible fish and shellfish from China
    Naiqing Yang
    Department of Environment Conservation, Ehime University, Tarumi 3 5 7, Matsuyama 790 8566, Japan
    Chemosphere 63:1342-52. 2006
    ..9 ng/g on wet weight basis, respectively. The daily intake of PCBs and organochlorine pesticides ingested by people living in these cities in China through fish and shellfish was estimated and compared with those observed in other areas...
  38. pmc A cross-sectional study of the association between persistent organochlorine pollutants and diabetes
    Lars Rylander
    Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, Department of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Environ Health 4:28. 2005
    ..We have assessed the association between serum levels of POPs and prevalence of diabetes in Swedish fishermen and their wives, with high consumption of fatty fish from the Baltic Sea...
  39. ncbi Reproductive success and contaminants in tree swallows (Tachycineta bicolor) breeding at a wastewater treatment plant
    Patti L Dods
    Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada
    Environ Toxicol Chem 24:3106-12. 2005
    ....
  40. ncbi The association between organochlorine and thyroid hormone levels in cord serum: a study from northern Thailand
    R Asawasinsopon
    Environmental Science Ph D Program, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand
    Environ Int 32:554-9. 2006
    ..76, P = 0.019). These results therefore suggest that exposure to DDT and its metabolites during fetal development may cause some effects on thyroid hormonal status in infants...
  41. ncbi Factors predicting organochlorine pesticide levels in pregnant Latina women living in a United States agricultural area
    A S A Bradman
    Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
    J Expo Sci Environ Epidemiol 17:388-99. 2007
    ..Although the weight of evidence from this study indicates that most exposure occurred before moving to the United States, the results for HCB indicate the possibility of ongoing exposure in this country...
  42. ncbi Distribution of polychlorinated biphenyls, organochlorine pesticides and polybrominated diphenyl ethers in human umbilical cord serum, maternal serum and milk from Wielkopolska region, Poland
    Kamila Jaraczewska
    Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, 6 Grunwaldzka St, 60 780 Poznan, Poland
    Sci Total Environ 372:20-31. 2006
    ..4), with BDE 47 being always the most abundant PBDE congener and, together with BDE 153, being present in all samples. In general, results found in the investigated group are at the low end of the concentration range measured in Europe...
  43. ncbi Semen quality and exposure to persistent organochlorine pollutants
    Gunnar Toft
    Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark
    Epidemiology 17:450-8. 2006
    ..The majority of studies have been conducted among selected populations of infertility clients or among occupational cohorts including a limited number of participants...
  44. pmc Fertility in four regions spanning large contrasts in serum levels of widespread persistent organochlorines: a cross-sectional study
    Gunnar Toft
    Department of Occupational Medicine, Aarhus University Hospital, Noerrebrogade 44, Build, 2C, DK 8000 Aarhus C, Denmark
    Environ Health 4:26. 2005
    ..Persistent organochlorine pollutants (POPs) may interfere with reproductive function but direct evidence in humans is very limited...
  45. pmc Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health Study
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Int J Cancer 120:642-9. 2007
    ....
  46. ncbi Serum polychlorinated biphenyl and organochlorine insecticide concentrations in a Faroese birth cohort
    Dana B Barr
    Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F17, Atlanta, GA 30341, USA
    Chemosphere 62:1167-82. 2006
    ....
  47. ncbi Levels of persistent organochlorine contaminants in fish from Korea and their potential health risk
    U H Yim
    Southern Coastal Environment Research Division, Korea Ocean Research and Development Institute, 391 Jangmok ri, Jangmok myon, Geoje shi, 656 834, Korea
    Arch Environ Contam Toxicol 48:358-66. 2005
    ..04 ng/g based on total PCBs), but the other compounds were mostly below SV values. Based on the estimated SVs, PCB compounds were identified as potential chemicals of concern...
  48. ncbi Human health risk assessment of organochlorines associated with fish consumption in a coastal city in China
    Q T Jiang
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Environ Pollut 136:155-65. 2005
    ..The hazard ratios (HRs), based on non-cancer endpoints were all less than 1.0, while the HRs based on cancer were greater than 1.0 for certain contaminants based on the 95th centile concentration in fish tissue...
  49. ncbi In utero and lactational exposure to an environmentally relevant organochlorine mixture disrupts reproductive development and function in male rats
    Mohamed Kheir Idris Anas
    Centre de Recherche en Biologie de la Reproduction, Departement de sciences animales, Universite Laval, Quebec, Canada G1K 7P4
    Biol Reprod 73:414-26. 2005
    ....
  50. ncbi Associations between serum levels of selected organochlorine compounds and endometriosis in infertile Japanese women
    Hiromasa Tsukino
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center Tsukiji, Tokyo, Japan
    Environ Res 99:118-25. 2005
    ..06). The results of this study provide some evidence that serum levels of these organochlorine compounds are not associated with an increased risk of endometriosis in infertile Japanese women...
  51. ncbi Organochlorines in carpet dust and non-Hodgkin lymphoma
    Joanne S Colt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Epidemiology 16:516-25. 2005
    ..The incidence of non-Hodgkin lymphoma (NHL) has risen over the past several decades. Reasons for this increase are largely unexplained...
  52. ncbi Organochlorine exposures during pregnancy and infant size at birth
    Sharon K Sagiv
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Epidemiology 18:120-9. 2007
    ..Organochlorines, including polychlorinated biphenyls (PCBs) and pesticides, are environmentally persistent contaminants that concentrate in the food chain as well in human adipose tissue and readily cross the placenta...
  53. pmc Thyroid hormones in pregnancy in relation to environmental exposure to organochlorine compounds and mercury
    Larissa Takser
    Laboratoire de Physiologie Materno Foetale, Universite du Quebec a Montreal, Montreal, Quebec, Canada
    Environ Health Perspect 113:1039-45. 2005
    ..Cord serum free thyroxin was negatively correlated with inorganic Hg. These results suggest that at even low levels of exposure, persistent environmental contaminants can interfere with thyroid status during pregnancy...
  54. ncbi Concentrations of environmental chemicals associated with neurodevelopmental effects in U.S. population
    Larry L Needham
    Organic Analytical Toxicology Branch, Mailstop F17, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341 3724, USA
    Neurotoxicology 26:531-45. 2005
    ..S. population. These data will continue to be collected in 2-year cycles and thus allow changes in human levels to be followed...
  55. pmc Distribution of persistent organochlorine contaminants in infertile patients from Tanzania and Germany
    Jürgen M Weiss
    Department of Obstetrics and Gynecology, University Clinic Luebeck, Ratzeburger Allee 160, D 23538, Luebeck, Germany
    J Assist Reprod Genet 23:393-9. 2006
    ..To test whether environmental pollutants could affect fertility in humans...
  56. ncbi Polychlorinated camphenes (toxaphenes), polybrominated diphenylethers and other halogenated organic pollutants in glaucous gull (Larus hyperboreus) from Svalbard and Bjørnøya (Bear Island)
    Dorte Herzke
    Norwegian Institute for Air Research, The Polar Environmental Centre, Hjalmar Johansen gt 14 N 9296 Tromsø, Norway
    Environ Pollut 121:293-300. 2003
    ..Concentrations of toxaphenes and PBDEs were up to 100-times lower than the concentrations of PCB and some of the pesticides. PCB and p,p/-DDE constituted 90% of the contaminants found...
  57. ncbi Elemental and organochlorine residues in bald eagles from Adak Island, Alaska
    Jordan H Stout
    U S Fish and Wildlife Service, Ecological Services, Anchorage Field Office, 605 West 4th Avenue, Room G 61, Anchorage, Alaska 99501, USA
    J Wildl Dis 38:511-7. 2002
    ..Furthermore, although mean polychlorinated biphenyl and pp'-dichlorodiphenyldichloroethylene concentrations were below acute toxic thresholds, they were surprisingly high given Adak Island's remote location...
  58. ncbi Organochlorines and heavy metals in pregnant women from the Disko Bay area in Greenland
    P Bjerregaard
    National Institute of Public Health, Section for Research in Greenland, Copenhagen, Denmark
    Sci Total Environ 245:195-202. 2000
    ..The contaminants are potentially toxic for several organ systems but the high concentrations of pollutants have so far not been shown to influence health in Greenland...
  59. ncbi Organochlorines and endometrial cancer risk
    E Weiderpass
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 9:487-93. 2000
    ..1 (95% confidence interval, 0.6-2.2; P for trend, 0.90). Our data do not support the hypothesis that the organochlorine exposure studied increases the risk for endometrial cancer...
  60. pmc Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study
    A P Høyer
    The Copenhagen Center for Prospective Population Studies, Harsdorffsvej 1B, 2tv, DK 1874 Frederiksberg C, Denmark
    BMC Cancer 1:8. 2001
    ..As estrogen receptor positive and negative breast cancer may represent different entities of the disease, this study was undertaken to evaluate organochlorines influence on breast cancer risk and survival according to receptor status...
  61. pmc Changes in maternal serum chlorinated pesticide concentrations across critical windows of human reproduction and development
    Michael S Bloom
    Department of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, One University Place, Rm 153, Rensselaer, NY 12144, USA
    Environ Res 109:93-100. 2009
    ..This underscores the importance of timing biospecimen collection to critical windows for development in the assessment of reproductive and/or developmental effects...
  62. ncbi Organochlorines and polybrominated diphenyl ethers in four geographically separated populations of Atlantic salmon (Salmo salar)
    Tore Christian Svendsen
    Department of Chemistry, Biotechnology, and Environmental Engineering, Aalborg University, Sohngardsholmsvej 57, DK 9000, Aalborg, Denmark
    J Environ Monit 9:1213-9. 2007
    ..The PBDE pattern changed between locations, with a significant separation of the fish from the freshwater and marine environment when analyzed using principal component analysis...
  63. doi Plasma organochlorine levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Sci Total Environ 402:176-83. 2008
    ..Our data do not support the hypothesis that plasma levels of p,p'-DDT, p,p'-DDE, HCB, and beta-HCH are associated with an overall increased risk of breast cancer among Japanese women...
  64. ncbi Exposure of Inuit in Greenland to organochlorines through the marine diet
    P Bjerregaard
    Section for Research in Greenland, National Institute of Public Health, Copenhagen, Denmark
    J Toxicol Environ Health A 62:69-81. 2001
    ..The age pattern indicates that bioaccumulation of PCB started in the 1950s, which is a likely date for the introduction of the compounds into the Arctic environment...
  65. pmc Host and environmental determinants of polychlorinated aromatic hydrocarbons in serum of adolescents
    Tim S Nawrot
    Studiecoördinatiecentrum, Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Faculteit Geneeskunde, Leuven, Belgium
    Environ Health Perspect 110:583-9. 2002
    ....
  66. ncbi Association of maternal blood pressure and hemoglobin level with organochlorines in human milk
    M K J Siddiqui
    Analytical Toxicology, Industrial Toxicology Research Centre, Lucknow, India
    Hum Exp Toxicol 21:1-6. 2002
    ..05). These results highlight the need for periodic monitoring to determine organochlorine contamination in human milk and assess their impact on mother and on neonatal health...
  67. pmc Serum organochlorine pesticide residues and risk of testicular germ cell carcinoma: a population-based case-control study
    Mary L Biggs
    Department of Biostatistics, School of Public Health and Community Medicine, University of Washington, Box 354922, Seattle, WA 98195 4922, USA
    Cancer Epidemiol Biomarkers Prev 17:2012-8. 2008
    ..Due to uncertainty regarding how well organochlorine levels measured in adulthood reflect exposures during early life, further research is needed using exposure measurements collected in utero or during infancy...
  68. ncbi Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium
    Michael G Wade
    Growth and Development Section, Environmental and Occupational Toxicology Section, Environmental Health Directorate, Health Canada, Tunney s Pasture, Ottawa, Ontario, Canada K1A 0L2
    Toxicol Sci 67:207-18. 2002
    ..These results demonstrate that low doses of ubiquitous environmental contaminants can alter HPT physiology in sexually mature males...
  69. pmc Infant exposure to chemicals in breast milk in the United States: what we need to learn from a breast milk monitoring program
    J S LaKind
    LaKind Associates, LLC, Catonsville, Maryland 21228, USA
    Environ Health Perspect 109:75-88. 2001
    ..A program of breast milk monitoring would serve to provide the information needed to assess infant exposures during breast-feeding and develop scientifically sound information on benefits and risks of breast-feeding in the United States...
  70. doi Serum organochlorines and breast cancer risk in Japanese women: a case-control study
    Hiroaki Itoh
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:567-80. 2009
    ..Here, we examined these associations in Japanese women in the largest study in Asian women to date...
  71. pmc Prevalence of self-reported diabetes and exposure to organochlorine pesticides among Mexican Americans: Hispanic health and nutrition examination survey, 1982-1984
    Shanna Cox
    Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Environ Health Perspect 115:1747-52. 2007
    ..Higher serum levels of organochlorine pesticides in Mexican Americans have been reported. Few studies have explored the association between pesticide exposure and diabetes...
  72. pmc Serum organochlorines and urinary porphyrin pattern in a population highly exposed to hexachlorobenzene
    Jordi Sunyer
    Respiratory and Environmental Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Catalonia, Spain
    Environ Health 1:1. 2002
    ..We aimed at analysing the association of individual urinary porphyrins with the serum concentrations of HCB and other organochlorine compounds in this highly exposed population...
  73. ncbi Health risk assessment on residents exposed to chlorinated hydrocarbons contaminated in groundwater of a hazardous waste site
    Lukas Jyuhn Hsiarn Lee
    Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei
    J Toxicol Environ Health A 65:219-35. 2002
    ..measured contaminant levels and exposure parameters to perform health risk assessment on seven chlorinated hydrocarbons. We measured groundwater concentrations of vinyl chloride, tetrachloroethylene, trichloroethylene, 1,1-..
  74. ncbi Serum levels of several organochlorine pesticides in farmers correspond with dietary exposure and local use history
    J W Brock
    National Center for Environmental Health NCEH, Centers for Disease Control, Atlanta, GA 30341, USA
    Toxicol Ind Health 14:275-89. 1998
    ..Previous reported use of chlordane on the North Carolina farms corresponded with measurable dietary levels of chlordance and higher serum trans-nonachlor levels than the levels in Iowa farm families...
  75. ncbi Evaluation of Mexican American migrant farmworker work practices and organochlorine pesticide metabolites
    M A Hernández-Valero
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Ind Med 40:554-60. 2001
    ..Epidemiologic studies often must rely upon questionnaire data to assess past exposures. The ability of questionnaires to rank migrant farmworkers according to past pesticide exposure is not known...
  76. ncbi Organochlorines and breast cancer risk
    Eugenia E Calle
    American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 52:301-9. 2002
    ..Women concerned about possible organochlorine exposure can be reassured that available evidence does not suggest an association between these chemicals and breast cancer...
  77. ncbi Chronic toxicity of a mixture of chlorinated alkanes and alkenes in ICR mice
    Fun In Wang
    Department of Veterinary Medicine, College of Agriculture, National Taiwan University, Taipei
    J Toxicol Environ Health A 65:279-91. 2002
    ..This study has demonstrated that the CA mixture is a potential carcinogen to male and female mice. These animal toxicology data may be important in assessing the health effects of individuals exposed to the CA mixture...
  78. ncbi Persistent chlordane concentrations in Long Island Sound sediment: implications from chlordane, 210Pb, and 137Cs profiles
    Lijia Yang
    Department of Earth and Atmospheric Sciences, City College of New York, CUNY, New York, New York 10031, USA
    Environ Sci Technol 41:7723-9. 2007
    ..S. Continued chlordane input and significant sediment mixing may have contributed to the persistent chlordane concentrations in surficial sediment, which poses long-term threats to benthic organisms in LIS...
  79. doi Assessment of the environmental and physiological processes determining the accumulation of organochlorine compounds in European mountain lake fish through multivariate analysis (PCA and PLS)
    M Felipe-Sotelo
    Department of Environmental Chemistry, IIQAB CSIC, C Jordi Girona 18 26, E 08034, Barcelona, Spain
    Sci Total Environ 404:148-61. 2008
    ..PLS models confirmed that temperature and altitude were the main factors influencing the accumulation of most organochlorine compounds in the lipids of the fish tissue...
  80. ncbi Bioaccumulation studies of organochlorinated pesticides in tissues of Cyprinus carpio
    Shanta Satyanarayan
    National Environmental Engineering Research Institute, Nagpur, India
    J Environ Sci Health B 40:397-412. 2005
    ..Based on actual BCF values, log Kow were calculated and the values are well within the reported values of 6.5 indicating efficient relationship between BCF and log Kow because beyond the 6.5 the bioconcentration levels off...
  81. ncbi Recent trends in organochlorine residues in mussels (Mytilus edulis) from the Mersey Estuary
    L Connor
    School of Biological Sciences, University of Liverpool, UK
    Mar Environ Res 52:397-411. 2001
    ....
  82. ncbi Brominated flame retardants and organochlorine pollutants in aquatic and terrestrial predatory birds of Belgium: levels, patterns, tissue distribution and condition factors
    V L B Jaspers
    Department of Biology, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Pollut 139:340-52. 2006
    ..BDE 183 and BDE 209 were only measured in the terrestrial birds. These results indicate that terrestrial birds may be more exposed to higher brominated BDE congeners than aquatic species...
  83. ncbi [Human biomonitoring investigations of organochlorine compounds -- PCB, DDE, HCB, beta- and gamma-HCH, PCDD/PCDF, Dioxin-like PCB's and polybrominated biphenyl ethers]
    T Gabrio
    Landesgesundheitsamt Baden Württemberg, Stuttgart
    Gesundheitswesen 67:302-11. 2005
    ..The difficulty to produce time series while the analyzing pollutants are more and more decreasing, as well as the change of the calculation base of the summation of parameters like I-TEQ NATO to TEQ WHO are discussed...
  84. ncbi Organochlorine residuals in groundwater of Pondicherry region
    M A Sivasankaran
    Department of Civil Engineering, Pondicherry Engineering College, Pondicherry
    J Environ Sci Eng 49:7-12. 2007
    ..Though the residual levels of pesticides in the study area were well below the acute toxicological problems, the major concern is for long term, chronic exposure from compounds that may be carcinogenic...
  85. ncbi Organochlorine pesticide and trace metal monitoring of Russian rivers flowing to the Arctic Ocean: 1990-1996
    L B Alexeeva
    Department of Environmental Monitoring and Pollution, SPA Typhoon, Institute of Experimental Meteorology, Obninsk, Russia
    Mar Pollut Bull 43:71-85. 2001
    ..Ni was monitored at too few rivers to estimate its total Russian flux. The fluxes for the HCHs considerably exceed previous estimates and indicate that the Arctic Ocean is not in balance as much as was previously believed...
  86. ncbi Contamination of persistent organic pollutants (POPs) and relevant management in China
    Wang Tieyu
    Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
    Environ Int 31:813-21. 2005
    ..Only some clauses mention POPs and lack pertinent, explicit statements on POP pollution and control. Legislation is urgently needed for more effective environmental management to enhance POP control...
  87. ncbi Non-destructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): IV. Hair versus soil analysis in exposure and risk assessment of organochlorine compounds
    Helga D'Havé
    Department of Biology, Ecophysiology, Biochemistry and Toxicology Group, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Pollut 145:861-8. 2007
    ....
  88. ncbi Distribution and fate of persistent organochlorine pesticides in coastal marine environment of Mumbai
    G G Pandit
    Environmental Assessment Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India
    Environ Int 32:240-3. 2006
    ..The alpha-HCH is found to be more dominant in fish samples whereas the gamma-HCH is major contributor in the sediment samples...
  89. ncbi Organohalogen chemicals in human blood from the United Kingdom
    Gareth O Thomas
    Department of Environmental Sciences, IENS, Lancaster University, Lancaster LA1 4YQ, UK
    Environ Pollut 141:30-41. 2006
    ..There is increasing regulation to control persistent and bioaccumulative chemicals, and establishing human exposure will help to identify substances which should be urgently phased out...
  90. ncbi The occurrence of organochlorines in marine avian top predators along a latitudinal gradient
    Cecilie Steffen
    Norwegian Institute for Nature Research, Unit for Arctic Ecology, The Polar Environmental Centre, Tromsø, Norway
    Environ Sci Technol 40:5139-46. 2006
    ....
  91. ncbi Temporal bioavailability of organochlorine pesticides and PCBs
    D Sethajintanin
    Department of Environmental and Molecular Toxicology and Food Safety and Environmental Stewardship Program, Oregon State University, Corvallis, Oregon 97331, USA
    Environ Sci Technol 40:3689-95. 2006
    ....
  92. ncbi [Residues and distribution character of organochlorine pesticides in stream sediments in southwestern suburb of Nanjing]
    Qiong An
    Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China
    Huan Jing Ke Xue 27:737-41. 2006
    ..Meanwhile, sedimentation of soil in streams could reduce OCPs input to the Yangtze River...
  93. ncbi Accumulation of PCBs and organochlorine pesticides in river-caught European river lamprey (Lampetra fluviatillis) in Finland
    L Merivirta
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Post Office Box 66, FIN 00014 Helsinki University, Finland
    Bull Environ Contam Toxicol 76:497-504. 2006
  94. ncbi Comparison of PCBs, organochlorine pesticides, and trace metals in cod liver from Georges Bank and Stellwagen Bank, USA and Canada
    Emily Monosson
    Mar Pollut Bull 52:591-7. 2006
  95. ncbi A survey and measurement of residues of lindane (organochlorine pesticides) in four species of the most consumed fish in the Caspian Sea (Iran)
    A G Ebadi
    Department of Biology, Islamic Azad University of Sari, Sari Branch, Iran
    Toxicol Ind Health 22:53-8. 2006
    ..05). However, the concentrations of lindane residues in the muscle were found to be less than the FAO/WHO (1993) recommended permissible intake and should not be of public concern in Mazandaran province...
  96. ncbi Distribution of organochlorine pesticides in surface water and sediments from Qiantang River, East China
    Rongbing Zhou
    Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang 310028, China
    J Hazard Mater 137:68-75. 2006
    ..The notable contamination was found in Fuchun reservoir. Composition analyses in sediments indicated a recent usage or discharge of lindane into the river...
  97. ncbi A preliminary risk assessment of organochlorines accumulated in fish to the Indo-Pacific humpback dolphin (Sousa chinensis) in the Northwestern waters of Hong Kong
    C L H Hung
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Environ Pollut 144:190-6. 2006
    ..The HCHs, total PCBs and heptachlor had comparatively high RQs and thus they should also be the priority organochlorines that would require further investigation...
  98. ncbi Organochlorine residues in fish and water samples from lake victoria, Uganda
    G N Kasozi
    Soil and Water Science Department, University of Florida, Gainesville, FL 326111 0290, USA
    J Environ Qual 35:584-9. 2006
    ..S. FDA, Australian, and German extraneous residue limits and maximum residue limits. The concentration of organochlorine residues in surface water within the Napoleon Gulf of Lake Victoria was below detection limit (0.1 microg L(-1))...
  99. ncbi Levels of organochlorine compounds in bivalves from the Japanese coastal waters: results from the environmental specimen bank in Japan
    Y Takazawa
    National Institute for Environmental Studies, 16 2 Onogawa, Tsukuba, Ibaraki 305 8506, Japan
    Bull Environ Contam Toxicol 75:561-8. 2005
  100. ncbi Gridded inventories of historical usage for selected organochlorine pesticides in Heilongjiang River Basin, China
    Li yan Liu
    School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harhin, China
    J Environ Sci (China) 18:822-6. 2006
    ..Data of usage and soil concentrations of sigma HCH in HRB match quite well to those in Shanghai region, and much higher soil concentration of sigma DDT in Shanghai region could be due to much heavier dicofol use in this region...
  101. ncbi Field validation of antioxidant enzyme biomarkers in mussels (Perna viridis) and clams (Ruditapes philippinarum) transplanted in Hong Kong coastal waters
    Sharon B De Luca-Abbott
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 51:694-707. 2005
    ..Multivariate statistical techniques indicated little relationship between the site patterns for antioxidant responses and the contaminant gradients identified in body burden analysis...

Research Grants67

  1. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..because bacterial monooxygenases prevent ChU, a greenhouse gas, from reaching the atmosphere, degrade chlorinated hydrocarbons in ground water, and are activated for bioremediation of oil spills...
  2. Prenatal Organochlorine Metabolites, Thyroid Function and Development
    PAM R FACTOR LITVAK; Fiscal Year: 2010
    ..This line of research could lead to prenatal interventions. ..
  3. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..because bacterial monooxygenases prevent ChU, a greenhouse gas, from reaching the atmosphere, degrade chlorinated hydrocarbons in ground water, and are activated for bioremediation of oil spills...
  4. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2007
    ..because bacterial monooxygenases prevent ChU, a greenhouse gas, from reaching the atmosphere, degrade chlorinated hydrocarbons in ground water, and are activated for bioremediation of oil spills...
  5. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    Stephen J Lippard; Fiscal Year: 2010
    ..The ability of these hydrocarbon-consuming "superbugs" to degrade chlorinated hydrocarbons has led to their application in the bioremediation of industrial wastewater, decontamination of seawater, ..
  6. CHLORINATED HYDROCARBONS EFFECTS ON MAMMALIAN SYSTEMS
    David Kupfer; Fiscal Year: 2003
    ..CYP3A4 catalyzes the metabolism of the majority of drugs and is involved in drug-drug interaction. Understanding the mechanism of 3A4 activity would be useful in predicting drug interactions and drug:drug-metabolite interactions. ..
  7. Sub-micrometer zero valent metal for in-situ remediation of contaminated aquifers
    JOHN FREIM; Fiscal Year: 2007
    In prior decades, chlorinated hydrocarbons were used for cleaning and degreasing. In numerous locations these toxic chemicals have been introduced into shallow aquifers and the public drinking water supply is adversely affected...
  8. Interaction of Nutrient & Organochlorine Absorption
    Patrick Tso; Fiscal Year: 2010
    ..The proposed research is important because of the biological and clinical importance of OCs in health and disease and they provide considerable new insights into how OCs are carried and delivered to the various organs in the body. ..
  9. Interaction of Nutrient & Organochlorine Absorption
    Patrick Tso; Fiscal Year: 2007
    ..The proposed research is important because of the biological and clinical importance of OCs in health and disease and they provide considerable new insights into how OCs are carried and delivered to the various organs in the body. ..
  10. CARBONYLS IN ENZYME MECHANISM--RAMAN CHARACTERIZATION
    Paul Carey; Fiscal Year: 1999
    ..4- chlorobenzoyl-CoA dehalogenase, which participates in the dechlorination of potentially harmful chlorinated hydrocarbons. In all cases, enzyme- carbonyl interactions are a key part of enzyme mechanism and in all cases, Raman ..
  11. Effects of organochlorines on male infertility
    JULIA WIRTH; Fiscal Year: 2006
    ..abstract_text> ..
  12. In Utero Organochlorine Exposure & Breast Density
    BARBARA COHN; Fiscal Year: 2009
    ..These women have not yet achieved the age of high breast cancer risk. The proposed project is an efficient use of existing resources for a unique 40-year follow-up study. ..
  13. In Utero Organochlorine Exposure & Breast Density
    BARBARA COHN; Fiscal Year: 2007
    ..These women have not yet achieved the age of high breast cancer risk. The proposed project is an efficient use of existing resources for a unique 40-year follow-up study. ..
  14. Feto-Maternal Pharmacokinetics of Abused Inhalants
    STEPHEN DEWEY; Fiscal Year: 2004
    ..indicate that 10% of an inhaled dose of toluene reaches the fetus whereas this fraction is 2% -4% for chlorinated hydrocarbons or for more highly substituted aromatics such as xylene and styrene...
  15. Prenatal Organochlorine Metabolites, Thyroid Function and Development
    Pam Factor Litvak; Fiscal Year: 2009
    ..This line of research could lead to prenatal interventions. ..