oxalic acids

Summary

Summary: Acids, salts, and derivatives of OXALIC ACID.

Top Publications

  1. ncbi Growth-inhibiting activity of active component isolated from Terminalia chebula fruits against intestinal bacteria
    H G Kim
    Faculty of Biotechnology and Center for Agricultural Science and Technology, College of Agriculture and Life Science, Chonbuk National University, Chonju 561 756, Korea
    J Food Prot 69:2205-9. 2006
  2. ncbi DDE remediation and degradation
    John E Thomas
    University of Florida, Soil and Water Science Deptartment, Gainesville, FL 32611, USA
    Rev Environ Contam Toxicol 194:55-69. 2008
  3. ncbi Light induced multiphase chemistry of gas-phase ozone on aqueous pyruvic and oxalic acids
    I Grgic
    Laboratory for Analytical Chemistry, National Institute of Chemistry, Hajdrihova 19, P O Box 660, SI 1001 Ljubljana, Slovenia
    Phys Chem Chem Phys 12:698-707. 2010
  4. doi Degradation mechanism of alachlor during direct ozonation and O(3)/H(2)O(2) advanced oxidation process
    Zhimin Qiang
    Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, China
    Chemosphere 78:517-26. 2010
  5. ncbi Mineralization of salicylic acid in acidic aqueous medium by electrochemical advanced oxidation processes using platinum and boron-doped diamond as anode and cathodically generated hydrogen peroxide
    Elena Guinea
    Laboratori d Electroquímica dels Materials i del Medi Ambient, Departament de Quimica Fisica, Facultat de Quimica, Universitat de Barcelona, Marti i Franques 1 11, 08028 Barcelona, Spain
    Water Res 42:499-511. 2008
  6. ncbi Use of citric acid for heavy metals extraction from contaminated sewage sludge for land application
    D Mundo del Dacera
    Environmental Technology Program, Sirindhorn International Institute of Technology SlIT, Thammasat University, P O Box 22, Pathumthani 12121, Thailand
    Water Sci Technol 54:129-35. 2006
  7. ncbi Ozonolytic depolymerization of polysaccharides in aqueous solution
    Y Wang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Carbohydr Res 319:141-7. 1999
  8. ncbi DNAPL remediation with in situ chemical oxidation using potassium permanganate. II. Increasing removal efficiency by dissolving Mn oxide precipitates
    X David Li
    Department of Geological Sciences, The Ohio State University, 125 South Oval Mall, Columbus, OH 43210, USA
    J Contam Hydrol 68:269-87. 2004
  9. ncbi Ethylene glycol poisoning
    Mila Lovric
    Clinical Institute of Laboratory Diagnosis, Zagreb University Hospital Center, Kispaticeva 12, Zagreb, Croatia
    Forensic Sci Int 170:213-5. 2007
  10. ncbi Effect of low molecular weight organic acids on adsorption and desorption of fluoride on variable charge soils
    Renkou Xu
    Institute of Soil Science, Chinese Academy of Sciences, PO Box 821, Nanjing 210008, China
    Environ Geochem Health 28:141-6. 2006

Scientific Experts

Detail Information

Publications93

  1. ncbi Growth-inhibiting activity of active component isolated from Terminalia chebula fruits against intestinal bacteria
    H G Kim
    Faculty of Biotechnology and Center for Agricultural Science and Technology, College of Agriculture and Life Science, Chonbuk National University, Chonju 561 756, Korea
    J Food Prot 69:2205-9. 2006
    ..These results may be an indication of at least one of the pharmacological properties of T. chebula fruits...
  2. ncbi DDE remediation and degradation
    John E Thomas
    University of Florida, Soil and Water Science Deptartment, Gainesville, FL 32611, USA
    Rev Environ Contam Toxicol 194:55-69. 2008
    ..g., citric and oxalic acids). DDE microbial degradation by dehalogenases, dioxygenases, and hydrolases occurs under the proper conditions...
  3. ncbi Light induced multiphase chemistry of gas-phase ozone on aqueous pyruvic and oxalic acids
    I Grgic
    Laboratory for Analytical Chemistry, National Institute of Chemistry, Hajdrihova 19, P O Box 660, SI 1001 Ljubljana, Slovenia
    Phys Chem Chem Phys 12:698-707. 2010
    ..Following the simultaneous ozone and light irradiation the first peak for pyruvic and oxalic acids (retention time = 3...
  4. doi Degradation mechanism of alachlor during direct ozonation and O(3)/H(2)O(2) advanced oxidation process
    Zhimin Qiang
    Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, China
    Chemosphere 78:517-26. 2010
    ..to the formation of low-molecular-weight byproducts including formic, acetic, propionic, monochloroacetic and oxalic acids as well as chloride ion (only detected in O(3)/H(2)O(2)). Nitrite and nitrate formation was negligible...
  5. ncbi Mineralization of salicylic acid in acidic aqueous medium by electrochemical advanced oxidation processes using platinum and boron-doped diamond as anode and cathodically generated hydrogen peroxide
    Elena Guinea
    Laboratori d Electroquímica dels Materials i del Medi Ambient, Departament de Quimica Fisica, Facultat de Quimica, Universitat de Barcelona, Marti i Franques 1 11, 08028 Barcelona, Spain
    Water Res 42:499-511. 2008
    ..2,6-dihydroxybenzoic, alpha-ketoglutaric, glycolic, glyoxylic, maleic, fumaric, malic, tartronic and oxalic acids are detected as oxidation products...
  6. ncbi Use of citric acid for heavy metals extraction from contaminated sewage sludge for land application
    D Mundo del Dacera
    Environmental Technology Program, Sirindhorn International Institute of Technology SlIT, Thammasat University, P O Box 22, Pathumthani 12121, Thailand
    Water Sci Technol 54:129-35. 2006
    Recent studies revealed that organic acids such as citric and oxalic acids seemed to be more promising as chemical extracting agents for removal of heavy metals from contaminated sludge, since they are biodegradable and can attain a ..
  7. ncbi Ozonolytic depolymerization of polysaccharides in aqueous solution
    Y Wang
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Carbohydr Res 319:141-7. 1999
    ..pathways include oxidative degradation by radical species that oxidize glycosyl residues to formic, acetic, and oxalic acids. The nonselective degradation caused by acids is minimized by basic buffers...
  8. ncbi DNAPL remediation with in situ chemical oxidation using potassium permanganate. II. Increasing removal efficiency by dissolving Mn oxide precipitates
    X David Li
    Department of Geological Sciences, The Ohio State University, 125 South Oval Mall, Columbus, OH 43210, USA
    J Contam Hydrol 68:269-87. 2004
    ..Once plugging reduced permeability and prevented further delivery of the oxidant, citric or oxalic acids were pumped into the flow tank to dissolve the Mn oxide precipitates...
  9. ncbi Ethylene glycol poisoning
    Mila Lovric
    Clinical Institute of Laboratory Diagnosis, Zagreb University Hospital Center, Kispaticeva 12, Zagreb, Croatia
    Forensic Sci Int 170:213-5. 2007
    ..Further toxicological analyses of glycolic and oxalic acids in serum and urine samples were performed by ion-chromatography (IC) method and showed high values in spot ..
  10. ncbi Effect of low molecular weight organic acids on adsorption and desorption of fluoride on variable charge soils
    Renkou Xu
    Institute of Soil Science, Chinese Academy of Sciences, PO Box 821, Nanjing 210008, China
    Environ Geochem Health 28:141-6. 2006
    ....
  11. ncbi Versatile gas/particle ion chromatograph
    S M Rahmat Ullah
    Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409 1061, USA
    Environ Sci Technol 40:962-8. 2006
    ..The system measures ammonia, organic acids (such as acetic, formic, and oxalic acids), HCl, HONO, SO2, HNO3, and the corresponding ions in the aerosol phase...
  12. ncbi Destruction of cresols by Fenton oxidation process
    V Kavitha
    Centre for Environmental Studies, Anna University, Chennai 600 025, India
    Water Res 39:3062-72. 2005
    ..The results showed that the cresols were completely oxidized and degraded into lower molecular weight aliphatic acids. Among the acids, acetic and oxalic acids were identified as the major products formed during the degradation.
  13. ncbi Detection and quantification of ligands involved in nickel detoxification in a herbaceous Ni hyperaccumulator Stackhousia tryonii Bailey
    Naveen P Bhatia
    Primary Industries Research Centre, School of Biological and Environmental Sciences, Central Queensland University, Rockhampton, Queensland 4702, Australia
    J Exp Bot 56:1343-9. 2005
    ..Malic acid was the dominant organic acid, followed by citric and oxalic acids. The molar ratio of Ni to malic acid was 1...
  14. ncbi Prestorage heat treatment to maintain nutritive and functional properties during postharvest cold storage of pomegranate
    Seyed Hossein Mirdehghan
    Department of Food Technology, EPSO, University Miguel Hernandez, ctra Beniel Km 3 2, 03312 Orihuela, Alicante, Spain
    J Agric Food Chem 54:8495-500. 2006
    ..Additionally, the levels of sugars (glucose and fructose) and organic acids (malic, citric, and oxalic acids) remained also at higher concentrations in arils from treated fruits...
  15. ncbi Spectra investigation on surface characteristics of graphene oxide nanosheets treated with tartaric, malic and oxalic acids
    Xiyao Teng
    College of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, PR China Institute of Health Research, Anhui University, Hefei 230601, PR China
    Spectrochim Acta A Mol Biomol Spectrosc 118:1020-4. 2014
    ..4 F g(-1) to 100.8, 112.4, and 147 F g(-1) after treated with tartaric, malic and oxalic acids, respectively...
  16. ncbi Influence of organic acids on the mobility of heavy metals in soil amended with some insecticides
    S U Khan
    Department of Applied Chemistry, Z H College of Engineering and Technology, Aligarh Muslim University, Aligarh 202 002
    Indian J Environ Health 44:212-9. 2002
    ..such as: endosulfan, chlorpyrifos, dimethoate and methyl demeton using distilled water, formic, acetic and oxalic acids as mobile phase...
  17. doi Effect of low-molecular-weight organic acids on kinetics release and fractionation of phosphorus in some calcareous soils of western Iran
    M Taghipour
    Department of Soil Science, College of Agriculture, Bu Ali Sina University, Hamadan, Iran
    Environ Monit Assess 185:5471-82. 2013
    ..In this study, we examined the effect of low-molecular-weight organic acids (malic, citric, and oxalic acids) on P release of some calcareous soils from western Iran...
  18. ncbi Reactions of hydroxyl radical with humic substances: bleaching, mineralization, and production of bioavailable carbon substrates
    J V Goldstone
    Woods Hole Oceanographic Institution, and Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA
    Environ Sci Technol 36:364-72. 2002
    ..Production rates of low molecular weight (LMW) acids including acetic, formic, malonic, and oxalic acids by reaction of SRFA and SRHA with OH* were measured using HPLC...
  19. doi Kinetics and mechanism for omethoate degradation by catalytic ozonation with Fe(III)-loaded activated carbon in water
    Zhimin Qiang
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, 18 Shuang Qing Road, Beijing 100085, China
    Chemosphere 90:1966-72. 2013
    ..organic acids and inorganic anions were also detected and quantified, including formic, acetic and oxalic acids as well as nitrate, sulfate and phosphate ions...
  20. doi Biodegradation of tribenuron methyl that is mediated by microbial acidohydrolysis at cell-soil interface
    Nan Xi Wang
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
    Chemosphere 86:1098-105. 2012
    ..TBM degradation by strain BW30 was dependent on glucose that was converted into lactic or oxalic acids. HPLC-MS analysis revealed two end-products from TBM degradation, and they were identical to the products from ..
  21. doi Enriching carbonylated proteins inside a microchip through the use of oxalyldihydrazide as a crosslinker
    Bryant C Hollins
    Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
    Lab Chip 12:2526-32. 2012
    ..This is the first report to suggest the use of immobilized oxalyldihydrazide on a microchip as an enrichment methodology for low abundance proteins in a sample...
  22. doi Ethylene glycol poisoning: quintessential clinical toxicology; analytical conundrum
    William H Porter
    Department of Pathology and Laboratory Medicine, University of Kentucky Medical Center, Lexington, KY, United States
    Clin Chim Acta 413:365-77. 2012
    ..review encompasses an assessment of analytical methods for the analytes relevant for the diagnosis and prognosis of ethylene glycol poisoning and of the role of the ethylene glycol metabolites, glycolic and oxalic acids, in its toxicity.
  23. doi Composition of hydroponic medium affects thorium uptake by tobacco plants
    Petr Soudek
    Laboratory of Plant Biotechnologies, Institute of Experimental Botany AS CR, v v i, Rozvojova 263, 165 02 Prague 6, Lysolaje, Czech Republic
    Chemosphere 92:1090-8. 2013
    ..Thorium was accumulated preferentially in the root system. The presence of citric, tartaric and oxalic acids in hydroponic medium increased thorium accumulation in all plant organs...
  24. doi Plums (Prunus domestica L.) are a good source of yeasts producing organic acids of industrial interest from glycerol
    Paula García-Fraile
    Departamento de Microbiologia y Genetica, Universidad de Salamanca, 37007 Salamanca, Spain
    Food Chem 139:31-4. 2013
    ..The production from glycerol of succinic, acetic, citric, malic and oxalic acids from C. oleophila and W. anomalus, and that of succinic, oxalic and acetic acids by P...
  25. doi Bioleaching of nickel and cobalt from lateritic chromite overburden using the culture filtrate of Aspergillus niger
    Supratim Biswas
    Department of Metallurgical and Material Engineering, Jadavpur University, Kolkata 700032, India
    Appl Biochem Biotechnol 170:1547-59. 2013
    ..The culture filtrate was analyzed for citric and oxalic acids, and contained only oxalic acid-the concentration of which increased with time...
  26. doi Photo-Fenton-like treatment of BPA: effect of UV light source and water matrix on toxicity and transformation products
    Merle Molkenthin
    Berlin University of Technology, Department of Water Quality and Control, Strasse des 17 Juni 135, 10623 Berlin, Germany
    Water Res 47:5052-64. 2013
    ..4-ethyl,1,3-benzenediol), as well as the ring opening products hexanoic acid methyl ester, fumaric, succinic and oxalic acids. A reaction pathway featuring hydroxylation, dimerization and ring opening steps is proposed.
  27. pmc Effects of the selective sigma receptor ligand, 1-(2-phenethyl)piperidine oxalate (AC927), on the behavioral and toxic effects of cocaine
    Rae R Matsumoto
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, USA
    Drug Alcohol Depend 118:40-7. 2011
    ..Earlier studies have shown that cocaine and many other abused substances interact with sigma receptors and that antagonism of these proteins can mitigate their actions...
  28. doi Pyrolysis of pine and gasification of pine chars--influence of organically bound metals
    A Aho
    Process Chemistry Centre, Åbo Akademi University, FI 20500 Turku Åbo, Finland
    Bioresour Technol 128:22-9. 2013
    ..elements in pine wood was performed with different acids, namely, nitric, sulfuric, hydrochloric and oxalic acids. No other major changes in the chemical composition of the biomass were observed except the removal of the ..
  29. ncbi Cadmium, lead and zinc leaching from smelter fly ash in simple organic acids--simulators of rhizospheric soil solutions
    Vojtech Ettler
    Institute of Geochemistry, Mineralogy and Mineral Resources, Charles University, Albertov 6, 12843 Prague 2, Czech Republic
    J Hazard Mater 170:1264-8. 2009
    ..5-168 h) in 500 microM solutions of acetic, citric, or oxalic acids to simulate the release of toxic metals (Cd, Pb, Zn) in rhizosphere-like environments...
  30. ncbi Therapeutic manipulation of the HIF hydroxylases
    Simon Nagel
    Acute Stroke Programme, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    Antioxid Redox Signal 12:481-501. 2010
    ..This article summarizes current understanding of the biochemistry of the HIF hydroxylases, identifies targets for their pharmacological manipulation, and discusses their potential in the therapeutic manipulation of the HIF system...
  31. pmc Attenuation of methamphetamine-induced effects through the antagonism of sigma (sigma) receptors: Evidence from in vivo and in vitro studies
    Rae R Matsumoto
    Department of Pharmacology, University of Mississippi, University, MS 38677, USA
    Eur Neuropsychopharmacol 18:871-81. 2008
    ..Together, the results demonstrate that AC927 protects against METH-induced effects, and suggests a new strategy for treating psychostimulant abuse...
  32. doi The influence of aluminium availability on phosphate uptake in Phaseolus vulgaris L. and Phaseolus lunatus L
    Tanja Mimmo
    Department of Agroenvironmental Sciences and Technologies, University of Bologna, Viale Fanin 40, 40127 Bologna, Italy
    Plant Physiol Biochem 47:68-72. 2009
    ..vulgaris L var. Red Kidney released fumaric acid and P. lunatus L. fumaric and oxalic acids which could have hindered further Al uptake...
  33. doi Antibacterial activity and spectral studies of trivalent chromium, manganese, iron macrocyclic complexes derived from oxalyldihydrazide and glyoxal
    D P Singh
    Department of Chemistry, National Institute of Technology, Kurukshetra, Haryana, 136 119, India
    J Enzyme Inhib Med Chem 24:883-9. 2009
    ..The biological activities of the metal complexes were tested in vitro against a number of pathogenic bacteria and some of the complexes exhibited remarkable antibacterial activities...
  34. doi Electrochemical incineration of high concentration azo dye wastewater on the in situ activated platinum electrode with sustained microwave radiation
    Guohua Zhao
    Department of Chemistry, Tongji University, Shanghai, China
    Chemosphere 77:188-93. 2009
    ..2,5-Dinitrophenol, p-nitrophenol, hydroquinone, benzoquinone, maleic and oxalic acids are the main intermediates during degradation of methyl orange...
  35. ncbi [Cu and Fe bioleaching in low-grade chalcopyrite and bioleaching mechanisms using Penicillium janthinellum strain GXCR]
    Yuan Zhou
    College of Life Science and Technology, Guangxi University, Nanning 530005, China
    Sheng Wu Gong Cheng Xue Bao 24:1993-2002. 2008
    ..05). The major organic acids for Cu and Fe bioleaching were citric and oxalic acids, respectively...
  36. ncbi Heavy metal contaminant remediation study of western Xiamen Bay sediment, China: laboratory bench scale testing results
    Luoping Zhang
    State Key Laboratory of Marine Environmental Science, Environmental Science Research Center, Xiamen University, Xiamen, Fujian, PR China
    J Hazard Mater 172:108-16. 2009
    ..This research provides additional useful information for sediment metal remediation technology development...
  37. doi Increase of ascorbic acid content and nutritional quality in spinach leaves during physiological acclimation to low temperature
    Simona Proietti
    Istituto di Biologia Agroambientale e Forestale, Consiglio Nazionale delle Ricerche, Viale Marconi 2, 05010 Porano TR, Italy
    Plant Physiol Biochem 47:717-23. 2009
    The effect of acclimation to 10 degrees C on the leaf content of ascorbic and oxalic acids, was investigated in spinach (Spinacia oleracea L.)...
  38. ncbi Reaction pathways of glucose oxidation by ozone under acidic conditions
    Olivier Marcq
    ICMUB LIMRES UMR 5260, Universite de Bourgogne, Faculte des Sciences Mirande, F 21100 Dijon, France
    Carbohydr Res 344:1303-10. 2009
    ..The origin of small molecules such as tartaric, erythronic, and oxalic acids is clarified...
  39. ncbi Kinetics of acid leaching of ilmenite decomposed by KOH Part 2. Leaching by H2SO4 and C2H2O4
    A A Nayl
    Hot Laboratory Center, Atomic Energy Authority, Inshas, Cairo, Egypt
    J Hazard Mater 168:793-9. 2009
    A kinetic study of the leaching of ilmenite paste (resulting from ilmenite treatment by KOH) by sulfuric and oxalic acids has been investigated...
  40. doi Thallium dynamics in contrasting light sandy soils--soil vulnerability assessment to anthropogenic contamination
    Ales Vanek
    Department of Soil Science and Soil Protection, Czech University of Life Sciences Prague, Kamycka 129, 165 21 Praha 6, Czech Republic
    J Hazard Mater 173:717-23. 2010
    ..Thermodynamic modeling showed that Tl mobilization in the presence of citric and oxalic acids was indirect and could be attributed to complexation of major elements (Ca, Mg, Al) originating from the ..
  41. doi Effects of amendments on soil availability and phytoremediation potential of aged p,p'-DDT, p,p'-DDE and p,p'-DDD residues by willow plants (Salix sp.)
    Francesca M Mitton
    Laboratorio de Ecotoxicologia, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata UNMdP, Mar del Plata, Argentina
    J Hazard Mater 203:62-8. 2012
    ..3 ng g(-1)) and p,p'-DDE (381.4 ng g(-1)) residues. The effect of root exudates, Tween 80 and citric and oxalic acids on DDTs desorption and availability from soil was tested together with the plant uptake and translocation...
  42. ncbi [Mitochondrial pyruvate carboxylase]
    Michinori Ito
    Department of Pediatrics, School of Medicine, University of Tokushima
    Nihon Rinsho 60:122-5. 2002
  43. doi Effects of cell lysis treatments on the yield of coenzyme Q10 following Agrobacterium tumefaciens fermentation
    - Yuting Tian
    College of Food Science and Engineering, Northwest A and F University, Yangling Shaanxi, P R China 712100
    Food Sci Technol Int 16:195-203. 2010
    ..acid is found the most effective in releasing CoQ₁₀, followed by lactic, sulfuric, phosphoric and oxalic acids. The most significant processing parameters, namely the ratio of acid solution volume and bacteria weight (A/B ..
  44. doi A ratiometric fluorescent probe for oxalate based on alkyne-conjugated carboxamidoquinolines in aqueous solution and imaging in living cells
    Chunsheng He
    Shanghai Key Laboratory of Chemical Biology, School of Pharmacy East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, PR China
    Dalton Trans 40:1034-7. 2011
    ..It shows highly selective "on-off" fluorescence changes with a more than 20 nm blue shift in wavelength for oxalic acids in aqueous solution. Moreover, it can fluorescently respond to oxalic acid in living cells.
  45. doi Seasonal variation in total phenolic and flavonoid contents and DPPH scavenging activity of Bellis perennis L. flowers
    Tomáš Siatka
    Department of Pharmacognosy, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic
    Molecules 15:9450-61. 2010
    ..with aluminium chloride after acidic hydrolysis of flower extracts (method 1) and by reaction with boric and oxalic acids in extracts without their modification (method 2)...
  46. pmc Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice
    Michael J Seminerio
    Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA
    Pharmacol Biochem Behav 98:12-20. 2011
    ..Together, the data suggest that AC927 (10 mg/kg) protects against methamphetamine-induced neurotoxicity. The reduction of methamphetamine-induced hyperthermia by AC927 may contribute to the observed neuroprotection in vivo...
  47. doi Effect of selected metal ions on the photocatalytic degradation of bog lake water natural organic matter
    Luis A Tercero Espinoza
    Water Chemistry, Engler Bunte Institut, Karlsruhe Institute of Technology, Engler Bunte Ring 1, 76131 Karlsruhe, Germany
    Water Res 45:1039-48. 2011
    ..Similarly, addition of Cu(2+) reduced the production of formic and oxalic acids, and reduced the bioavailability of the partially degraded NOM.
  48. ncbi Aqueous coordination chemistry and photochemistry of uranyl(VI) oxalate revisited: a density functional theory study
    Satoru Tsushima
    Institut fur Radiochemie, Forschungszentrum Dresden Rossendorf FZD, Bautzner Landstraße 400, 01328, Dresden, Germany
    Dalton Trans 39:10953-8. 2010
    ..1:2) complex as the main photoreactive species are thus unlikely to apply, because the two oxalic acids are bound to uranium in a chelating binding mode...
  49. doi Small-molecule inhibitors of NADPH oxidase 4
    Gabor Borbely
    Vichem Chemie Research Ltd, Budapest, Hungary
    J Med Chem 53:6758-62. 2010
    ..Twenty-four compounds inhibited Nox4 activity with low-micromolar IC(50) values of which three were selected for further drug development...
  50. ncbi [Degradation mechanism of phenol with electrogenerated hydrogen peroxide on a Pd/C gas-diffusion electrode]
    Hui Wang
    College of Environmental Science and Engineering, Beijing Forestry University, Beijing 100083, China
    Huan Jing Ke Xue 31:1506-12. 2010
    ..and benzoquinone as the main aromatic intermediates, and adipic, maleic, fumaric, succinic, malonic, and oxalic acids as the main aliphatic carboxylic intermediates. A reaction scheme involving all these intermediates was proposed...
  51. doi Discrimination of apple juice and herbal liqueur brands with solid-state electrodes covered with polyaniline and thiacalixarenes
    G A Evtugyn
    AM Butlerov Chemistry Institute, Kazan State University, Kazan, Russian Federation
    Talanta 82:613-9. 2010
    ..Besides, the electrodes developed make it possible to detect individual antioxidants (ascorbic, malic, oxalic acids, hydroquinone, and quercetin) in the range from 5.0x10(-6) to 1...
  52. pmc Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches
    Nathan R Rose
    The Department of Chemistry and the Oxford Centre for Integrative Systems Biology, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, United Kingdom
    J Med Chem 53:1810-8. 2010
    ..A crystal structure of JMJD2A in complex with one of the potent inhibitors was obtained; modeling other inhibitors based on this structure predicts interactions that enable improved inhibition for some compounds...
  53. pmc Ascorbate metabolism and the developmental demand for tartaric and oxalic acids in ripening grape berries
    Vanessa J Melino
    The University of Adelaide, School of Agriculture, Food and Wine, Private Mail Bag 1, Glen Osmond, SA 5064, Australia
    BMC Plant Biol 9:145. 2009
    ..The purpose of this study was to gain insights into Asc metabolism in wine grapes (Vitis vinifera c.v. Shiraz.) and thus ascertain whether the developmental demand for TA and OA synthesis influences Asc accumulation in the berry...
  54. ncbi Electrochemical incineration of diclofenac in neutral aqueous medium by anodic oxidation using Pt and boron-doped diamond anodes
    Enric Brillas
    Laboratori d Electroquímica de Materials i del Medi Ambient, Departament de Quimica Fisica, Facultat de Quimica, Universitat de Barcelona, Marti i Franques 1 11, 08028 Barcelona, Spain
    Chemosphere 79:605-12. 2010
    ..For AO with Pt, high amounts of malic, succinic, tartaric and oxalic acids are accumulated in the bulk and the N-derivatives produced are rapidly destroyed with loss of NH4+...
  55. ncbi Synthesis and spectroscopic studies of biologically active compounds derived from oxalyldihydrazide and benzil, and their Cr(III), Fe(III) and Mn(III) complexes
    D P Singh
    Department of Chemistry, National Institute of Technology, Kurukshetra 136 119, India
    Eur J Med Chem 44:1731-6. 2009
    ..Some of these complexes have been found to exhibit remarkable antibacterial activities...
  56. doi Oxaliplatin doublets in non-small cell lung cancer: a literature review
    Diego Cortinovis
    Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, 20133 Milan, Italy
    Lung Cancer 60:325-31. 2008
    ..We performed a literature search in order to better understand the possible role of oxaliplatin-based combinations in advanced NSCLC treatment strategies...
  57. ncbi Degradation of chemical substances using wet peroxide oxidation under mild conditions
    Kiyokazu Okawa
    Fukuoka University Institute for Recycling and Environmental Control System, Wakamatsu ku, Kitakyushu, Japan
    J Hazard Mater 127:68-72. 2005
    ..Acetic and oxalic acids were mineralized using WPO. TOC removal rate of acetic acid was highest in the solution of pH 2.5...
  58. ncbi A novel atomic force microscope operating in liquid for in situ investigation of electrochemical preparation of porous alumina
    Haijun Zhang
    Department of Optical Engineering, Zhejiang University, Hangzhou 310027, People s Republic of China
    Microsc Res Tech 66:126-31. 2005
    ..As a typical example of applications, the results of this work show that the new AFM is an ideal and powerful tool for in-situ observation and study of materials or samples in aqueous solutions...
  59. ncbi Effects of dissolved organic matter on toxicity and bioavailability of copper for lettuce sprouts
    Shoko Inaba
    Graduate School of Bioagricultural Sciences, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8601, Japan
    Environ Int 31:603-8. 2005
    ..Low molecular weight organic acids (citric, malic, and oxalic acids) increased the toxicity and bioavailability of Cu, but low concentrations of the synthetic chelators ..
  60. ncbi Degradation of tert-butyl alcohol in dilute aqueous solution by an O3/UV process
    Temesgen Garoma
    Department of Civil and Environmental Engineering, San Diego State University, San Diego, California 92182, USA
    Environ Sci Technol 38:5246-52. 2004
    ..formaldehyde were identified as primary intermediates, whereas pyruvaldehyde and acetic, formic, pyruvic, and oxalic acids were generated as a result of further oxidation process...
  61. ncbi Solid phase extraction procedure for urinary organic acid analysis by gas chromatography mass spectrometry
    Aiping Liu
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 806:283-7. 2004
    ..They were below 5 nmole with the exception of malonic and oxalic acids and mevalonic acid lactone...
  62. ncbi Occurrence and characterization of hypovirulence in the tan sclerotial isolate S10 of Sclerotinia sclerotiorum
    Guo Quing Li
    Agriculture and Agri Food Canada, Lethbridge Research Centre, Lethbridge AB, TIJ 4BI Canada
    Mycol Res 107:1350-60. 2003
    ..The existence of dsRNA-free hypovirulence in S10 progenies suggests that another hypovirulence mechanism may exist in S. sclerotiorum...
  63. ncbi Role of organic acids in enhancing the desorption and uptake of weathered p,p'-DDE by Cucurbita pepo
    Jason C White
    Department of Soil and Water, The Connecticut Agricultural Experiment Station, 123 Huntington Street, New Haven, CT 06504, USA
    Environ Pollut 124:71-80. 2003
    ..containing weathered p,p'-DDE (300 ng/g, dry weight) were periodically amended with distilled water, citric or oxalic acids (0.01 M). Plants receiving water removed 1.7% of the p,p'-DDE from the soil...
  64. ncbi [Recurrent episodes of acidosis with encephalopathy in a hemodialysis program patient with short bowel syndrome]
    P Angelet
    Unidad Nefrológica del Hospital de la Santa Creu, Jesús Tortosa
    Nefrologia 22:196-8. 2002
    ..The detection of acidosis in predialysis measurements and the acute episodes of acidosis, made it necessary to administer bicarbonate to the patient and give him additional hemodialysis sessions...
  65. ncbi sigma(2) Receptors regulate changes in sphingolipid levels in breast tumor cells
    Keith W Crawford
    Department of Pharmacology, Howard University College of Medicine, Washington, DC 20059, USA
    Eur J Pharmacol 443:207-9. 2002
    ..Both effects were attenuated by the novel sigma(2) receptor antagonist, N-phenethylpiperidine oxalate (AC927). sigma(2) Receptors may produce effects on cell growth and apoptosis by regulating the sphingolipid pathway...
  66. ncbi [Effects of organic acids on the toxicity of cadmium during ryegrass growth]
    Min Liao
    College of Environment and Natural Resources Science, Zhejiang University, Hangzhou 310029
    Ying Yong Sheng Tai Xue Bao 13:109-12. 2002
    ..low molecular weight organic acids, and the sequence of this influence was: citric acid > acetic acid > oxalic acids. The concentration of Cd decreased gradually as a result of increasing the concentration of humic acid, which ..
  67. ncbi [Effect of organic acids on soil chemical behavior of lead and cadmium and their toxicity to plants]
    Q Lin
    Department of Environmental Science, Zhejiang University, Hangzhou 310029
    Ying Yong Sheng Tai Xue Bao 12:619-22. 2001
    The interaction between organic acids (citric and oxalic acids) and heavy metals was examined in this paper...
  68. ncbi Photooxidation of the phenylazonaphthol AO20 on TIO2: kinetic and mechanistic investigations
    C Galindo
    Laboratoire de Chimie Textile, Ecole Nationale Superieure de Chimie de Mulhouse, France
    Chemosphere 45:997-1005. 2001
    ..original dye anchored to the oxide surface systematically undergoes fast decomposition until it is transformed into CO2 or aliphatic acids (formic, acetic, oxalic acids), which react rather slowly with hydroxyl radicals or trapped holes.
  69. ncbi Formation of reduced carbonaceous matter in basalts and xenoliths: reaction of C-O-H gases on olivine crack surfaces
    T N Tingle
    Department of Geology, Stanford University, CA 94305, USA
    Geochim Cosmochim Acta 57:3245-9. 1993
    ....
  70. ncbi Synthesis of radialene-shaped pyrroles by multiple-anion-capture reactions of 1,3-dianions
    P Langer
    Institut für Organische Chemie der Georg August Universität Göttingen, Germany
    Chemistry 7:2617-27. 2001
    ..The cyclization products can be considered as aza-analogues of the pharmacologically relevant substance class of 3-acetyltetramic acids. A rationalization of the experimental results is given based on quantum chemical computations...
  71. ncbi Determination of the Maillard product oxalic acidmonolysinylamide (OMA) in heated milk products by ELISA
    K Hasenkopf
    Friedrich Alexander University Erlangen, Institute of Pharmacy and Food Chemistry, Schuhstrasse 19, D 91052 Erlangen, Germany
    Nahrung 45:206-9. 2001
    ..For some samples intra- and interassay variation were determined. The ELISA was used to measure OMA-formation in heated milk and commercially available infant formula...
  72. ncbi The role of root exudates in aluminium resistance and silicon-induced amelioration of aluminium toxicity in three varieties of maize (Zea mays L.)
    P S Kidd
    Laboratorio de Fisiologia Vegetal, Facultad de Ciencias, Universidad Autonoma de Barcelona, E 08193 Bellaterra, Spain
    J Exp Bot 52:1339-52. 2001
    ..The flavonoid-type phenolics, to date unconsidered, appear to play a role in the mechanism(s) of Si-induced amelioration of Al toxicity...
  73. ncbi Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]-dimethyl-amine
    U Gulini
    Dipartimento di Scienze Chimiche, Universita degli Studi di Camerino, Italy
    Bioorg Med Chem Lett 11:247-50. 2001
    ..These results may well lead to the development of new potent antimuscarinic drugs lacking a cationic head...
  74. ncbi Fomepizole treatment of ethylene glycol poisoning in an infant
    C R Baum
    Department of Pediatrics, Northwestern University Medical School, Chicago, IL 60614 3394, USA
    Pediatrics 106:1489-91. 2000
    The enzyme alcohol dehydrogenase metabolizes ingested ethylene glycol (EG) to the toxic compounds glycolic and oxalic acids. Renal failure, acidosis, hypocalcemia, and death may follow...
  75. pmc Nickel deficiency disrupts metabolism of ureides, amino acids, and organic acids of young pecan foliage
    Cheng Bai
    United States Department of Agriculture, Agricultural Research Service, South Atlantic Area, Southeast Fruit and Tree Nut Research Laboratory, Byron, Georgia 31008, USA
    Plant Physiol 140:433-43. 2006
    ..Disruption of carbon metabolism was also via accumulation of lactic and oxalic acids. The results indicate that mouse-ear, a key morphological symptom, is likely linked to the toxic accumulation ..
  76. doi Mineralization of the biocide chloroxylenol by electrochemical advanced oxidation processes
    Marcel Skoumal
    Laboratori d Electroquímica dels Materials i del Medi Ambient, Departament de Quimica Fisica, Facultat de Quimica, Universitat de Barcelona, Marti i Franques 1 11, 08028 Barcelona, Spain
    Chemosphere 71:1718-29. 2008
    ..are identified as aromatic by-products, and maleic, malonic, pyruvic, acetic and oxalic acids are found as generated carboxylic acids...
  77. ncbi Degradation of diuron in aqueous solution by dielectric barrier discharge
    Jingwei Feng
    State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment Nanjing University, Nanjing 210093, PR China
    J Hazard Mater 154:1081-9. 2008
    ..The main degradation pathway of diuron by DBD involved a series of dechlorination-hydroxylation, dealkylation and oxidative opening of the aromatic ring processes...
  78. ncbi Ecotoxicology of ozone: bioactivation of extracellular ascorbate
    Heinrich Sandermann
    ecotox freiburg, Schubertstr 1, D 79104 Freiburg, Germany
    Biochem Biophys Res Commun 366:271-4. 2008
    ..Peroxy-l-threonic and peroxy-oxalic acids are now derived as further decomposition products on the basis of Criegee-type ozone chemistry...
  79. ncbi Capillary electrophoresis for short chain organic acids in faeces Reference values in a Mediterranean elderly population
    A Garcia
    Universidad San Pablo CEU, Facultad de Farmacia, Campus Monteprincipe, 28668 Boadilla del Monte, Madrid, Spain
    J Pharm Biomed Anal 46:356-61. 2008
    ..validated for a representative group of compounds: acetic, propionic butyric, 2-hydroxybutiric, isovaleric, and oxalic acids, including the comparison of results with ionic chromatography...
  80. ncbi Decomposition of toxic pollutants in landfill leachate by ozone after coagulation treatment
    Tatyana Poznyak
    Superior School of Chemical Engineering, National Polytechnic Institute ESIQIE IPN, Edif 7, UPALM, C P 07738, Mexico, DF, Mexico
    J Hazard Mater 152:1108-14. 2008
    ..In the HPLC results we identify malonic and oxalic acids. The initial concentrations of these acids were 19 mg/L and 214 mg/L, respectively...
  81. ncbi Changes in crested wheatgrass root exudation caused by flood, drought, and nutrient stress
    Amelia Henry
    Dep of Plants, Soils, and Biometeorology, Utah State Univ, Logan UT 84321, USA
    J Environ Qual 36:904-12. 2007
    ..Fumaric, malonic, succinic, and oxalic acids were also detected in the exudates of all treatments...
  82. ncbi Degradation of the herbicide 2,4-DP by anodic oxidation, electro-Fenton and photoelectro-Fenton using platinum and boron-doped diamond anodes
    Enric Brillas
    Laboratori d Electroquímica dels Materials i del Medi Ambient, Departament de Quimica Fisica, Facultat de Quimica, Universitat de Barcelona, Marti i Franques 1 11, 08028 Barcelona, Spain
    Chemosphere 68:199-209. 2007
    ..Chlorohydroquinone, chloro-p-benzoquinone and maleic, fumaric, malic, lactic, pyruvic, acetic, formic and oxalic acids are detected as products by chromatographic techniques...
  83. ncbi Recovery of metals from Cuban nickel tailings by leaching with organic acids followed by precipitation and magnetic separation
    C M F Hernández
    High Institute of Mining and Metallurgy Dr Antonio Núnez Jiménez, MOA, Cuba
    J Hazard Mater 139:25-30. 2007
    ..34% Ni, 0.08% Co and 44.2% Fe was investigated by using tartaric and oxalic acids at different concentrations...
  84. ncbi Evidence for oligomer formation in clouds: reactions of isoprene oxidation products
    Katye E Altieri
    Institute of Marine and Coastal Sciences, Department of Environmental Sciences, Rutgers NOAA CMER Program, Rutgers, The State University of New Jersey, New Brunswick 08901 8521, USA
    Environ Sci Technol 40:4956-60. 2006
    ..No evidence of oligomer formation was found in a standard mix composed of pyruvic, glyoxylic, and oxalic acids prepared in the same matrix as the samples analyzed using the same instrument conditions...
  85. ncbi [Decoloring and spectral properties analysis of innoxious ultraviolet absorbents]
    Yi Wen Fang
    Department of Chemistry, Shantou University, Shantou 515063, China
    Guang Pu Xue Yu Guang Pu Fen Xi 26:1303-5. 2006
    ..5% (w/w), the ultraviolet ray transmission was smaller than 0.3% in 200-370 nm, and it increased slightly from 370 nm. There was a maximum value at 400 nm, approaching 12%...
  86. ncbi Mechanism of decolorization and degradation of CI Direct Red 23 by ozonation combined with sonolysis
    Shuang Song
    College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People s Republic of China
    Chemosphere 66:1782-8. 2007
    ..with mass spectrometry in the absence of pH buffer, while nitrate and sulfate ions and formic, acetic and oxalic acids were detected by ion chromatography...
  87. ncbi Electrochemical oxidation of oxalic acid at highly boron-doped diamond electrodes
    Tribidasari A Ivandini
    Department of Chemistry, Faculty of Science and Technology, Keio University, 3 14 1 Hiyoshi, Yokohama 223 8522, Japan
    Anal Chem 78:3467-71. 2006
    ....
  88. ncbi 1,4- vs 1,3-prototropic mechanism for intramolecular double proton transfer reaction in monothiooxalic acid. Theoretical investigation of potential energy surface
    Christophe Raynaud
    Laboratoire de Physique Quantique, UMR 5626, IRSAMC, Université P Sabatier, 118 Route Narbonne, 31062 Toulouse, France
    J Phys Chem A 109:9646-52. 2005
    ..The main conclusion is: the 1,4-prototropic mechanism, mainly considered as a one step concerted exchange of protons, is the most favored from an energetic point of view...
  89. ncbi The effect of oxalic acid incorporation on the setting time and strength of a glass-ionomer cement
    Leon Hugh Prentice
    School of Dental Science, University of Melbourne, Parkville, VIC 3010, Australia
    Acta Biomater 2:109-12. 2006
    ..Oxalic acid may be a useful reaction modifier in glass-ionomer systems. It accelerated the setting reaction without affecting strength, but was limited to low concentrations because of its relatively poor solubility in water...
  90. ncbi Antimicrobial, spectral, magnetic and thermal studies of Cu(II), Ni(II), Co(II), UO(2)(VI) and Fe(III) complexes of the Schiff base derived from oxalylhydrazide
    Khlood Abou Melha
    Department of Chemistry, Education College for Girls, Abha, Saudi Arabia, KSA
    J Enzyme Inhib Med Chem 23:285-95. 2008
    ..The ligand and its metal complexes were tested against a Gram + ve bacteria (Staphylococcus aureus), a Gram -ve bacteria (Escherichia coli), and a fungi (Candida albicans). The tested compounds exhibited high antibacterial activities...
  91. ncbi Antibacterial Schiff bases of oxalyl-hydrazine/diamide incorporating pyrrolyl and salicylyl moieties and of their zinc(II) complexes
    Zahid H Chohan
    J Enzyme Inhib Med Chem 17:1-7. 2002
    ..Some of them showed promising biological activity in inhibiting the growth of such organisms...
  92. ncbi Effects of organic and inorganic acids on phosphorus release from municipal sludge
    N B Pakdil
    Dept of Environmental Engineering, Dokuz Eylul University, Engineering Faculty, Kaynaklar Campus, Buca, 35160, Izmir, Turkey
    Water Sci Technol 56:87-94. 2007
    ..the effects of inorganic acids (sulphuric acid, hydrochloric acid, nitric acid) and organic acids (citric acid, oxalic acids) for phosphorus recovery from sludge and struvite precipitation results...
  93. ncbi Oxalate contributes to the resistance of Gaillardia grandiflora and Lupinus sericeus to a phytotoxin produced by Centaurea maculosa
    Tiffany L Weir
    Department of Horticulture and Landscape Architecture, Graduate Program in Cell and Molecular Biology, Colorado State University, Fort Collins, 80523, USA
    Planta 223:785-95. 2006
    ..Heynh grown in vitro alleviated the phytotoxic effects of catechin, supporting the field experiments and suggesting that root-secreted oxalate may also act as a chemical facilitator for plant species that do not secrete the compound...

Research Grants16

  1. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2000
    ..Together, we anticipate that these studies will lead to the development of new and effective agents for the treatment of cocaine overdose and addiction. ..
  2. Synthesis and Evaluation of Sigma-Active Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2009
    ..It is anticipated that the results of this project will stimulate the rational development of new a2 receptor probes and ultimately contribute to improved treatments for psychostimulant abuse. ..
  3. Synthesis and Evaluation of Sigma-Active Cocaine Antagonists
    Rae R Matsumoto; Fiscal Year: 2010
    ..It is anticipated that the results of this project will stimulate the rational development of new a2 receptor probes and ultimately contribute to improved treatments for psychostimulant abuse. ..
  4. Synthesis and Evaluation of Sigma-Active Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2009
    ..It is anticipated that the results of this project will stimulate the rational development of new a2 receptor probes and ultimately contribute to improved treatments for psychostimulant abuse. ..
  5. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2007
    ..It is anticipated that the results of this project will facilitate the development of new and effective treatments for cocaine abuse. ..
  6. Synthesis and Evaluation of Sigma-Active Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2008
    ..It is anticipated that the results of this project will stimulate the rational development of new a2 receptor probes and ultimately contribute to improved treatments for psychostimulant abuse. ..
  7. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2007
    ..It is anticipated that the results of this project will facilitate the development of new and effective treatments for cocaine abuse. ..
  8. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2006
    ..It is anticipated that the results of this project will facilitate the development of new and effective treatments for cocaine abuse. ..
  9. Synthesis & Evaluation of Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2003
    ..It is anticipated that the results of this project will lead to the development of new and effective treatments for cocaine addiction and overdose. ..
  10. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2003
    ..Together, we anticipate that these studies will lead to the development of new and effective agents for the treatment of cocaine overdose and addiction. ..
  11. Synthesis & Evaluation of Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2002
    ..It is anticipated that the results of this project will lead to the development of new and effective treatments for cocaine addiction and overdose. ..
  12. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2002
    ..Together, we anticipate that these studies will lead to the development of new and effective agents for the treatment of cocaine overdose and addiction. ..
  13. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2001
    ..Together, we anticipate that these studies will lead to the development of new and effective agents for the treatment of cocaine overdose and addiction. ..
  14. Synthesis & Evaluation of Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2001
    ..It is anticipated that the results of this project will lead to the development of new and effective treatments for cocaine addiction and overdose. ..
  15. SIGMA LIGANDS FOR THE TREATMENT OF COCAINE OVERDOSE
    Rae Matsumoto; Fiscal Year: 2001
    ..Together, we anticipate that these studies will lead to the development of new and effective agents for the treatment of cocaine overdose and addiction. ..
  16. Synthesis and Evaluation of Sigma-Active Cocaine Antagonists
    Rae Matsumoto; Fiscal Year: 2009
    ..It is anticipated that the results of this project will stimulate the rational development of new a2 receptor probes and ultimately contribute to improved treatments for psychostimulant abuse. ..