dimethylamines

Summary

Top Publications

  1. ncbi Photocatalytic degradation of N-nitrosodimethylamine: mechanism, product distribution, and TiO2 surface modification
    Jaesang Lee
    School of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang 790- 784, Korea
    Environ Sci Technol 39:6800-7. 2005
  2. ncbi Beta-deuterium isotope effects on amine basicity, "inductive" and stereochemical
    Charles L Perrin
    Department of Chemistry 0358, University of California, San Diego, La Jolla, California 92093-0358, USA
    J Am Chem Soc 125:15008-9. 2003
  3. ncbi Expression, purification, and aggregation studies of His-tagged thermoalkalophilic lipase from Bacillus thermocatenulatus
    Nils Helge Schlieben
    , , , , Germany
    Protein Expr Purif 34:103-10. 2004
  4. ncbi [Dimethylamine]
    Kei Miyanaka
    Division of Medical and Pharmaceutical Research, Nephrology, Kumamoto University Graduate School
    Nippon Rinsho 62:512-4. 2004
  5. ncbi Methylohalomonas lacus gen. nov., sp. nov. and Methylonatrum kenyense gen. nov., sp. nov., methylotrophic gammaproteobacteria from hypersaline lakes
    Dimitry Yu Sorokin
    Winogradsky Institute of Microbiology, Russian Academy of Sciences, Prospect 60 let Octyabrya 7 2, 117811 Moscow, Russia
    Int J Syst Evol Microbiol 57:2762-9. 2007
  6. ncbi Stereochemistry of beta-deuterium isotope effects on amine basicity
    Charles L Perrin
    Department of Chemistry 0358, University of California, San Diego, La Jolla, California 92093 0358, USA
    J Am Chem Soc 127:9641-7. 2005
  7. ncbi Sampling and analytical methodology development for the determination of primary and secondary low molecular weight amines in ambient air
    Mathieu Fournier
    Institut de Recherche Robert Sauve en Sante et en Securite du Travail, 505 De Maisonneuve Blvd West, Montreal, H3A 3C2, Canada
    J Environ Monit 10:379-86. 2008
  8. ncbi Mid-infrared spectroscopic investigation of methylamines by a continuous-wave difference-frequency-generation-based system
    Dilyan Marinov
    ETH Zurich, Institute for Quantum Electronics, Laser Spectroscopy and Sensing Laboratory, Schafmattstrasse 16, CH 8093 Zurich, Switzerland
    Appl Opt 47:1956-62. 2008
  9. ncbi Inhibition of ATP hydrolysis by thermoalkaliphilic F1Fo-ATP synthase is controlled by the C terminus of the epsilon subunit
    Stefanie Keis
    Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, P.O. Box 56, Dunedin, New Zealand
    J Bacteriol 188:3796-804. 2006
  10. ncbi Overexpression and purification of the RyR1 pore-forming region
    Gil Bu Kang
    Department of Life Science, Gwangju Institute of Science and Technology GIST, Gwangju, Korea
    Protein Pept Lett 14:742-6. 2007

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Detail Information

Publications116 found, 100 shown here

  1. ncbi Photocatalytic degradation of N-nitrosodimethylamine: mechanism, product distribution, and TiO2 surface modification
    Jaesang Lee
    School of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang 790- 784, Korea
    Environ Sci Technol 39:6800-7. 2005
    ..The PCD of NDMA on surface-fluorinated TiO2 was also highly enhanced but favored the formation of MA over the formation of DMA...
  2. ncbi Beta-deuterium isotope effects on amine basicity, "inductive" and stereochemical
    Charles L Perrin
    Department of Chemistry 0358, University of California, San Diego, La Jolla, California 92093-0358, USA
    J Am Chem Soc 125:15008-9. 2003
    ..The values are consistent with a cos(2) dependence on dihedral angle, with no detectable angle-independent inductive effect...
  3. ncbi Expression, purification, and aggregation studies of His-tagged thermoalkalophilic lipase from Bacillus thermocatenulatus
    Nils Helge Schlieben
    , , , , Germany
    Protein Expr Purif 34:103-10. 2004
    ..For the concentrated lipase, the availability of 5% 2-propanol was sufficient to hold the lipase in monomeric form and no additional detergent was needed...
  4. ncbi [Dimethylamine]
    Kei Miyanaka
    Division of Medical and Pharmaceutical Research, Nephrology, Kumamoto University Graduate School
    Nippon Rinsho 62:512-4. 2004
  5. ncbi Methylohalomonas lacus gen. nov., sp. nov. and Methylonatrum kenyense gen. nov., sp. nov., methylotrophic gammaproteobacteria from hypersaline lakes
    Dimitry Yu Sorokin
    Winogradsky Institute of Microbiology, Russian Academy of Sciences, Prospect 60 let Octyabrya 7 2, 117811 Moscow, Russia
    Int J Syst Evol Microbiol 57:2762-9. 2007
    ..nov., sp. nov. (type strain AMT 1(T) =DSM 15732(T) =NCCB 100209(T) =UNIQEM U238(T))...
  6. ncbi Stereochemistry of beta-deuterium isotope effects on amine basicity
    Charles L Perrin
    Department of Chemistry 0358, University of California, San Diego, La Jolla, California 92093 0358, USA
    J Am Chem Soc 127:9641-7. 2005
    ..The isotope effect is attributed to a lowered zero-point energy of a C-H bond adjacent to an amine nitrogen, arising from delocalization of either a syn or an anti lone pair, and with no detectable angle-independent inductive effect...
  7. ncbi Sampling and analytical methodology development for the determination of primary and secondary low molecular weight amines in ambient air
    Mathieu Fournier
    Institut de Recherche Robert Sauve en Sante et en Securite du Travail, 505 De Maisonneuve Blvd West, Montreal, H3A 3C2, Canada
    J Environ Monit 10:379-86. 2008
    ..This new strategy will be useful in evaluating workplace air since a unique sampling system will be used, independent of the amine to be quantified...
  8. ncbi Mid-infrared spectroscopic investigation of methylamines by a continuous-wave difference-frequency-generation-based system
    Dilyan Marinov
    ETH Zurich, Institute for Quantum Electronics, Laser Spectroscopy and Sensing Laboratory, Schafmattstrasse 16, CH 8093 Zurich, Switzerland
    Appl Opt 47:1956-62. 2008
    ..Future developments are discussed to further improve these detection limits that are currently still about 2 orders of magnitude higher than required for direct methylamine monitoring in human breath...
  9. ncbi Inhibition of ATP hydrolysis by thermoalkaliphilic F1Fo-ATP synthase is controlled by the C terminus of the epsilon subunit
    Stefanie Keis
    Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, P.O. Box 56, Dunedin, New Zealand
    J Bacteriol 188:3796-804. 2006
    ..Reconstituted TA2F(o)F(1)(epsilon(6A)) exhibited ATPase activity that correlated with increased ATP-driven proton pumping, confirming that the epsilon subunit also inhibits ATPase activity of TA2F(o)F(1)...
  10. ncbi Overexpression and purification of the RyR1 pore-forming region
    Gil Bu Kang
    Department of Life Science, Gwangju Institute of Science and Technology GIST, Gwangju, Korea
    Protein Pept Lett 14:742-6. 2007
    ..The protein was then purified using nickel-affinity chromatography and gel filtration. Gel filtration analysis confirmed that the RyR1 fragment containing the pore-forming region (amino acids 4829-5037) is sufficient to form a tetramer...
  11. ncbi Hoechst 33258 as a pH-sensitive probe to study the interaction of amine oxide surfactants with DNA
    Laura Goracci
    CEMIN, Centro di Eccellenza per Materiali Innovativi Nanostrutturati, Dipartimento di Chimica, , 06123 Perugia, Italy
    Chembiochem 6:197-203. 2005
    ....
  12. ncbi Phenols and amine induced HO* generation during the initial phase of natural water ozonation
    Marc-Olivier Buffle
    Swiss Federal Institute of Aquatic Science and Technology (Eawag, Uberlandstrasse 133, Postfach 611, CH-8600 Dubendorf, Switzerland
    Environ Sci Technol 40:3057-63. 2006
    ..Pretreatment of phenol-containing water with HOCl or HOBr did not decrease HO* generation, while the same treatment of dimethylamine-containing water considerably reduced HO* generation...
  13. ncbi N-nitrosodimethylamine (NDMA) formation during ozonation of dimethylamine-containing waters
    Przemysław Andrzejewski
    Department of Water Treatment Technology, Faculty of Chemistry, Adam Mickiewicz University, ul Drzymały 24, 60 613 Poznań, Poland
    Water Res 42:863-70. 2008
    ..The reaction may have potential importance for water treatment technology assuming reasonable micrograms per liter of DMA concentrations in raw waters...
  14. ncbi Additive impairment of the barrier function and irritation by biogenic amines and sodium lauryl sulphate: a controlled in vivo tandem irritation study
    J W Fluhr
    Skin Physiology Laboratory, Department of Dermatology and Allergology, Friedrich Schiller University, Erfurter Strasse 35, DE 07740 Jena, Germany
    Skin Pharmacol Physiol 18:88-97. 2005
    ..The results are suggestive that in the food-processing industry the simultaneous contact with biogenic amines and harmful detergents like SLS should be minimized...
  15. ncbi Homeostatic signature of anabolic steroids in cattle using 1H-13C HMBC NMR metabonomics
    Marc Emmanuel Dumas
    Biological Chemistry Section, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, United Kingdom
    J Proteome Res 4:1493-502. 2005
    ....
  16. ncbi The trimethylamine methyltransferase gene and multiple dimethylamine methyltransferase genes of Methanosarcina barkeri contain in-frame and read-through amber codons
    L Paul
    Department of Microbiology, Ohio State University, Columbus, Ohio
    J Bacteriol 182:2520-9. 2000
    ..Thus, the genes encoding the three types of methyltransferases that initiate methanogenesis from methylamine contain in-frame amber codons that are suppressed during expression of the characterized methyltransferases...
  17. ncbi Investigations into biochemical changes of genetic hypertensive rats using 1H nuclear magnetic resonance-based metabonomics
    Kazuki Akira
    School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
    Hypertens Res 28:425-30. 2005
    ....
  18. ncbi Metabolism of trimethylamines in kelp bass (Paralabrax clathratus) and marine and freshwater pink salmon (Oncorhynchus gorbuscha)
    R P Charest
    Department of Biological Sciences, University of Southern California, Los Angeles 90089
    J Comp Physiol B 158:609-19. 1988
    ..4% of administered dose). Labeled TMA and TMAO, however, were detected in liver after [14C]betaine administration to a marine salmon, indicating that TMA-mono-oxygenase is present in salmon liver.(ABSTRACT TRUNCATED AT 400 WORDS)..
  19. ncbi High-resolution NMR spectroscopy as a method of studying human biological fluids in normal state and pathology
    V P Kutyshenko
    Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Oblast, 142290 Russia
    Dokl Biochem Biophys 410:300-3. 2006
  20. ncbi Adsorption of phenolic compounds from aqueous solutions by aminated hypercrosslinked polymers
    Zhen mao Jiang
    The State Key Laboratory of Pollution Control and Resource Reuse, Department of Environment Engineering, Nanjing University, Nanjing 210093, China
    J Environ Sci (China) 19:135-40. 2007
    ..The adsorption impetus increased as quantity of hydroxyl groups increased, but the adsorption capacity decreased due to the drop of the matching degree of the aperture of resins and the diameter of adsorbate molecules...
  21. ncbi Biofiltration of trimethylamine, dimethylamine, and methylamine by immobilized Paracoccus sp. CP2 and Arthrobacter sp. CP1
    Kuo Ling Ho
    Department of Biological Science and Technology, National Chiao Tung University, Hsin Chu, Taiwan, Republic of China
    Chemosphere 72:250-6. 2008
    ..CP1 in the co-immobilization biofilter...
  22. ncbi Temperature-induced sedimentation to dispersion of ionic vesicles
    Hideya Kawasaki
    Department of Chemistry, Faculty of Science, Kyushu University 33, Hakozaki, Higashi ku, Fukuoka 812 8581, Japan
    J Colloid Interface Sci 284:349-53. 2005
    ..The combined effect of the thermally induced dissociation of the counterions from the vesicle and a hydrogen bonding between the nonionic and the cationic head groups is likely to be responsible for this unique behavior...
  23. ncbi Enhanced adsorption of alkyl glucosides on the silica/water interface by addition of amine oxides
    Maria K Matsson
    YKI, Institute for Surface Chemistry, Box 5607, SE 114 86 Stockholm, Sweden
    Langmuir 21:2766-72. 2005
    ..Both these effects are explained by incorporation of DDAO in the mixed micelles above cmc(mix), which leads to a desorption of DDAO from the surface...
  24. ncbi N-nitrosodimethylamine formation during treatment with strong oxidants of dimethylamine containing water
    P Andrzejewski
    Department of Water Treatment Technology, Faculty of Chemistry, Adam Mickiewicz University, ul Drzymały 24, Poznan, Poland
    Water Sci Technol 56:125-31. 2007
    ....
  25. ncbi Complete mineralization of dodecyldimethylamine using a two-membered bacterial culture
    A G Kroon
    Akzo Nobel Chemicals Research, Arnhem, The Netherlands
    Environ Microbiol 3:131-6. 2001
    ..A two-membered culture was therefore imperative for growth on dodecyldimethylamine under nitrogen-limited conditions, whereas a pure culture of B. cepacia was capable of growth on dodecyldimethylamine under carbon-limited conditions...
  26. ncbi Solvation dynamics of DCM in a polypeptide-surfactant aggregate: gelatin-sodium dodecyl sulfate
    Arnab Halder
    Physical Chemistry Department, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700 032, India
    Langmuir 20:653-7. 2004
    ..The critical association concentration (cac) of SDS for gelatin is determined to be 0.5 +/- 0.1 mM...
  27. ncbi Novel N,N '-diacyl-1,3-diaminopropyl-2-carbamoyl bivalent cationic lipids for gene delivery--synthesis, in vitro transfection activity, and physicochemical characterization
    Michael Spelios
    Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    FEBS J 275:148-62. 2008
    ..Taken together, the results suggest that well-hydrated and highly elastic cationic lipids with increased acyl chain fluidity and minimal cytotoxicity elicit high transfection activity...
  28. ncbi Effect of amphiphilic surfactant LDAO on the solubilization of DOPC vesicles and on the activity of Ca(2+)-ATPase reconstituted in DOPC vesicles
    J Karlovska
    Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University, Odbojarov 10, 832 32 Bratislava, Slovakia
    Gen Physiol Biophys 26:290-7. 2007
    ..The ATPase activity decrease at higher LDAO concentrations was caused by the bilayer deformation. This deformation resulted in the formation of non-bilayer aggregates in LDAO+DOPC system...
  29. ncbi Hydrogen ion titration of alkyldimethylamine oxides by 13C and 1H NMR and conventional methods
    Rie Kakehashi
    Osaka Municipal Technical Research Institute, Morinomiya, Osaka 536 8553, Japan
    J Colloid Interface Sci 289:498-503. 2005
    ..The intrinsic logarithmic dissociation constants of the micelle were 5.9+/-0.1 for H2O, and 6.5+/-0.1 for D2O...
  30. ncbi Small-angle neutron scattering study of N-dodecyl-N,N-dimethylamine N-oxide induced solubilization of dioleoylphosphatidylcholine bilayers in liposomes
    D Uhrikova
    Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University, Bratislava, Slovakia
    Gen Physiol Biophys 20:183-9. 2001
    ..5 < DDAO : DOPC < 3.5, and transition to globular particles (spheroid micelles) at DDAO: DOPC > 4. In bilayers or/and bilayer fragments, DDAO modulates the thickness of the bilayer...
  31. ncbi Purification, crystallization, and properties of F1-ATPase complexes from the thermoalkaliphilic Bacillus sp. strain TA2.A1
    Achim Stocker
    , , Wolfgang-Pauli-Strasse 10, , Switzerland
    J Struct Biol 152:140-5. 2005
    ..A1 membranes. ATPase assays of F(1)Deltadelta crystals exhibited latent ATP hydrolytic activity that was highly stimulated by lauryldimethylamine oxide, a hallmark of the native enzyme...
  32. ncbi Self-assembly of ATP synthase subunit c rings
    Ignacio Arechaga
    The Medical Research Council Dunn Human Nutrition Unit, Hills Road, CB2 2YK, Cambridge, UK
    FEBS Lett 515:189-93. 2002
    ..The results suggest that the ability of subunit c to form rings is determined by its primary structure...
  33. ncbi Influence of the order of reagent addition on NDMA formation during chloramination
    I Marie Schreiber
    Department of Chemical Engineering, Yale University, Mason Lab 313b, 9 Hillhouse Avenue, New Haven, Connecticut 06520, USA
    Environ Sci Technol 39:3811-8. 2005
    ..Chloramination strategies are suggested that may reduce NDMA formation by nearly an order of magnitude...
  34. ncbi Nitrosamine formation pathway revisited: the importance of chloramine speciation and dissolved oxygen
    I Marie Schreiber
    Department of Chemical Engineering, Yale University, New Haven, Connecticut 06520, USA
    Environ Sci Technol 40:6007-14. 2006
    ..With the improved understanding of the nitrosamine formation pathway, strategies are suggested that could significantly reduce nitrosamine formation during chloramination...
  35. ncbi Toxicological evaluation of mixtures of nonionic surfactants, alone and in combination with oil
    Warangkana Warisnoicharoen
    Pharmacy Department, King's College London, University of London, Franklin Wilkins Building, 150 Stamford Street, London, SE1 9NN, United Kingdom
    J Pharm Sci 92:859-68. 2003
    ....
  36. ncbi Antimicrobial and diffusional correlation of N-alkyl betaines and N-alkyl-N,N-dimethylamine oxides from semisolids
    C R Birnie
    Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, 600 South 43rd Street, Philadelphia, PA 19104, USA
    J Pharm Sci 90:1386-94. 2001
    ..The formulations delayed release in the same rank order as the contact time kill analysis: hydroxyethylcellulose gel > poloxamer gel > cream...
  37. ncbi Synthesis, in vitro transfection activity and physicochemical characterization of novel N,N'-diacyl-1,2-diaminopropyl-3-carbamoyl-(dimethylaminoethane) amphiphilic derivatives
    Ahmad Aljaberi
    Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA
    Chem Phys Lipids 133:135-49. 2005
    ..4 mN/m. In conclusion, increased acyl chain fluidity and high molecular elasticity of cationic lipids were found to correlate with improved transfection activity...
  38. ncbi Effect of additives on photodegradation of 1,3,5-trichlorobenzene in aqueous surfactant solutions
    Y Itoh
    Department of Functional Polymer Science, Faculty of Textile Science and Technology Shinshu University, Ueda, Nagano, Japan
    J Environ Sci Health A Tox Hazard Subst Environ Eng 40:1013-9. 2005
    ....
  39. ncbi Migration of methyl groups between aliphatic amines in water
    Brian P Callahan
    Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, 27599-7260, USA
    J Am Chem Soc 125:310-1. 2003
    ..With dimethylamine as a common acceptor, trimethylsulfonium ion was found to be approximately 104-fold more reactive than the tetramethylammonium ion at ambient temperature...
  40. ncbi Solution structure of the integral human membrane protein VDAC-1 in detergent micelles
    Sebastian Hiller
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Science 321:1206-10. 2008
    ..NMR measurements revealed the binding sites of VDAC-1 for the Bcl-2 protein Bcl-x(L), for reduced beta-nicotinamide adenine dinucleotide, and for cholesterol. Bcl-x(L) interacts with the VDAC barrel laterally at strands 17 and 18...
  41. ncbi Structure of myelin P2 protein from equine spinal cord
    Dominic J B Hunter
    Department of Chemistry, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland
    Acta Crystallogr D Biol Crystallogr 61:1067-71. 2005
    ..187 (Rfree=0.233). The structure contains a molecule of the detergent LDAO and HEPES buffer in the binding cavity and is otherwise analogous to other cellular retinol-binding proteins...
  42. ncbi AFM characterization of tilt and intrinsic flexibility of Rhodobacter sphaeroides light harvesting complex 2 (LH2)
    Simon Scheuring
    Institut Curie, UMR CNRS 168 and LRC CEA 34V, 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05, France
    J Mol Biol 325:569-80. 2003
    ....
  43. ncbi Resolution of the V1 ATPase from Manduca sexta into subcomplexes and visualization of an ATPase-active A3B3EG complex by electron microscopy
    Vincenzo F Rizzo
    , Fachrichtung 2.5-Biophysik, D-66421 Homburg, Germany
    J Biol Chem 278:270-5. 2003
    ..sexta (Radermacher, M., Ruiz, T., Wieczorek, H., and Grüber, G. (2001) J. Struct. Biol. 135, 26-37)...
  44. ncbi Self-assembling peptide detergents stabilize isolated photosystem I on a dry surface for an extended time
    Patrick Kiley
    Center for Biomedical Engineering NE47-379, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    PLoS Biol 3:e230. 2005
    ..These observations suggest that the peptide detergents may effectively stabilize membrane proteins in the solid-state. These designed peptide detergents may facilitate the study of diverse types of membrane proteins...
  45. ncbi 4,5,6-Trisubstituted piperidinones as conformationally restricted ceramide analogues: synthesis and evaluation as inhibitors of sphingosine and ceramide kinases and as NKT cell-stimulatory antigens
    Thresen Mathew
    Laboratorium fur Organische Chemie, Departement Chemie und Angewandte Biowissenschaften, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich
    Chem Biodivers 6:1688-715. 2009
    ..The L-arabino and the L-ribo dimethylamines 21-24, the L-gluco ceramide analogues 43, 46a, and 47, and the L-altro ceramide analogues 51a and 52 did not ..
  46. ncbi Quantitative structure-activity relationship modeling of acute toxicity of quaternary alkylammonium sulfobetaines to Daphnia magna
    Joanna Davies
    University of Wales Swansea, Singleton Park, Swansea SA2 8PP, United Kingdom
    Environ Toxicol Chem 23:2111-5. 2004
    ..general formula RN+(CH3)2(CH2)nSO3-, where n = 2 to 4, and were synthesized by reacting the corresponding N,N-dimethylamines with either sodium-2-chloroethanesulfonate (n = 2), 1,3-propanesultone (n = 3), or 1,4-butanesultone (n = 4)...
  47. ncbi Fragmentation pathways of N(G)-methylated and unmodified arginine residues in peptides studied by ESI-MS/MS and MALDI-MS
    Peter M Gehrig
    Institute of Biochemistry, University of Zurich, Zurich, Switzerland
    J Am Soc Mass Spectrom 15:142-9. 2004
    ..The neutral losses of mono- and dimethylamines permit the differentiation between aDMA and sDMA.
  48. ncbi Biodegradability and ecotoxicity of amine oxide based surfactants
    M T Garcia
    Surfactant Technology Department, IIQAB CSIC, Jordi Girona 18 26, 08034 Barcelona, Spain
    Chemosphere 69:1574-8. 2007
    ..11 to 11 mg l(-1)) proved to be more sensitive to the toxic effects of the amine oxide based surfactants than crustacea (IC(50) from 6.8 to 45 mg l(-1)). The fatty amido amine oxide showed the lowest aquatic toxicity...
  49. ncbi Growth hormone treatment improves markers of systemic nitric oxide bioavailability via insulin-like growth factor-I
    Thomas Thum
    Universitatsklinikum, Medizinische Klinik I Kardiologie, 97080 Wurzburg, Germany
    J Clin Endocrinol Metab 92:4172-9. 2007
    ..Animal data demonstrate increased NO availability to be mediated via an increase in IGF-I plasma levels. Thus, GH treatment enhances systemic NO bioavailability via IGF-I and may be beneficial in certain cardiovascular diseases...
  50. ncbi Insights on co-catalyst-promoted enamine formation between dimethylamine and propanal through ab initio and density functional theory study
    Mahendra P Patil
    Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India
    J Org Chem 72:8202-15. 2007
    ..The results are found to be in concurrence with the available reports on the rate acceleration by co-catalysts in the Michael reaction between enamine and methyl vinyl ketone under neat conditions...
  51. ncbi Dimethylamine and diet
    S C Mitchell
    Biomolecular Medicine, SORA Division, Faculty of Medicine, Imperial College London, South Kensington, London, UK
    Food Chem Toxicol 46:1734-8. 2008
    ..Freshwater trout, plaice and prawns gave no discernable effect. It seems that not all fish and seafoods may be treated equally with regards to human dimethylamine exposure and that the situation is more complicated than at first appears...
  52. ncbi Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats
    Chang Z Zhu
    Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064 3500, USA
    Eur J Pharmacol 580:314-21. 2008
    ....
  53. ncbi Regulation of CD40 reconstitution into a liposome using different ratios of solubilized LDAO to lipids
    Kyung Eun Lee
    Laboratory of Cell Engineering and 3D Structure, School of Life Sciences and Biotechnology, Korea University, 1, 5 Ka, Anam Dong, Sungbuk Ku, Seoul, Republic of Korea
    Colloids Surf B Biointerfaces 62:51-7. 2008
    ..The results of the present study show that the detergent ratio had an effect on the structure of the liposome and the amount of CD40 that was reconstituted into the liposome...
  54. ncbi Dependence of N-nitrosodimethylamine photodecomposition on the irradiation wavelength: excitation to the s(2) state as a doorway to the dimethylamine radical ground-state chemistry
    Daniel Pelaez
    Department of Physical Chemistry, Faculty of Sciences, University of Malaga, E 29071 Malaga, Spain
    J Org Chem 72:4741-9. 2007
    ....
  55. ncbi Degradation of amine-based water treatment polymers during chloramination as N-nitrosodimethylamine (NDMA) precursors
    Sang Hyuck Park
    School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
    Environ Sci Technol 43:1360-6. 2009
    ..Polyamines' tertiary amine chain ends play a major role in their NDMA-FP, while polyDADMACs' NDMA-FP is related to degradation of the quaternary ammonium ring group...
  56. ncbi Size-dependent reactions of ammonium bisulfate clusters with dimethylamine
    Bryan R Bzdek
    Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA
    J Phys Chem A 114:11638-44. 2010
    ..The results of this study give further evidence to suggest that ambient sub-3 nm diameter particles are likely to contain aminium salts rather than ammonium salts...
  57. ncbi SANS investigation of the photosynthetic machinery of Chloroflexus aurantiacus
    Kuo Hsiang Tang
    Department of Biology, Washington University in St Louis, Missouri, USA
    Biophys J 99:2398-407. 2010
    ..Finally, two populations of chlorosome particles are suggested in our SANS measurements...
  58. ncbi Kinetics and equilibrium adsorption studies of dimethylamine (DMA) onto ion-exchange resin
    Qinhai Hu
    College of Environmental and Resources Science, Zhejiang University, Hangzhou 310029, Zhejiang, China
    J Hazard Mater 185:677-81. 2011
    ..DMA adsorption on ZGSPC106 fitted well to the pseudo-second-order kinetic model. Furthermore, the adsorption mechanism was discussed by Fourier transform infrared spectroscopy (FT-IR) analysis...
  59. ncbi Intramolecular charge delocalization and nonlinear optical properties of push-pull chromophore 1-(4-N,N-dimethylaminopyridinium) acetic acid bromide monohydrate from vibrational spectra
    C Jesintha John
    Centre for Molecular and Biophysics Research, Department of Physics, Mar Ivanios College, Thiruvananthapuram, 695 015 Kerala, India
    Spectrochim Acta A Mol Biomol Spectrosc 78:264-72. 2011
    ..The Natural Bond Orbital analysis confirms the occurrence of strong intermolecular O-H⋯O hydrogen bonding...
  60. ncbi The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings
    Y V Bobkov
    Whitney Laboratory, Center for Smell and Taste, St Augustine, FL, USA
    Biochim Biophys Acta 1808:1120-8. 2011
    ..5 Å. These findings provide important insight into the basic fundamental properties and function of TRPA1 channels in general and human TRPA1 channel in particular...
  61. ncbi Adsorption of dimethylamine from aqueous solution by manganese dioxide
    L Yang
    State Key Laboratory of Urban Water Resources and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin, 150090, China
    Water Sci Technol 63:45-50. 2011
    ..According to the results, it suggests that the adsorption is primarily brought about by electrostatic interaction between DMA and MnO₂ surface...
  62. ncbi Chloramination of nitrogenous contaminants (pharmaceuticals and pesticides): NDMA and halogenated DBPs formation
    Julien Le Roux
    Laboratoire de Chimie et Microbiologie de l Eau CNRS UMR 6008, Université de Poitiers ENSIP, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France
    Water Res 45:3164-74. 2011
    ..Previous research used dimethylamine (DMA) as a model precursor of NDMA, but certain widely used tertiary dimethylamines (e.g. the pharmaceutical ranitidine) show much higher conversion rates to NDMA than DMA...
  63. ncbi PolyDADMAC and dimethylamine as precursors of N-nitrosodimethylamine during ozonation: reaction kinetics and mechanisms
    Lokesh Padhye
    School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
    Environ Sci Technol 45:4353-9. 2011
    ..The mechanistic understanding from this study can help develop source control strategies for minimization of NDMA formation risk at water and wastewater utilities...
  64. ncbi Tailored synthesis of mesoporous platinum replicas using double gyroid mesoporous silica (KIT-6) with different pore diameters via vapor infiltration of a reducing agent
    Yoji Doi
    Faculty of Science and Engineering, Waseda University, Ohkubo 3 4 1, Shinjuku, Tokyo 169 8555, Japan
    Chem Commun (Camb) 46:6365-7. 2010
    ..Through controlling the complementary pore size, it becomes possible to selectively deposit Pt into one side pore of the Ia3d bicontinuous structure, thereby forming a mesoporous Pt replica with relatively large mesopores (over 10 nm)...
  65. ncbi Development of an on-line weak-cation exchange liquid chromatography-tandem mass spectrometric method for screening aldehyde products in biological matrices
    Mark Eggink
    VU University Amsterdam, Faculty of Science, Section of Analytical Chemistry and Applied Spectroscopy, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands
    J Chromatogr B Analyt Technol Biomed Life Sci 877:3937-45. 2009
    ..An in vitro model shows how derivatized aldehydes in human and rat plasma are detected. Finally, plasma treated with radical inducer shows elevated aldehyde species compared to untreated plasma...
  66. ncbi Computational study on the aminolysis of beta-hydroxy-alpha,beta-unsaturated ester via the favorable path including the formation of alpha-oxo ketene intermediate
    Lu Jin
    College of Chemistry, Sichuan University, Chengdu 610064, PR China
    J Phys Chem A 112:4501-10. 2008
    ..Being independent of the concentration of amine, the first process obeys the first-order rate law...
  67. ncbi Optimization of normal-phase chromatographic separation of compounds with primary, secondary and tertiary amino groups
    M Kagan
    Discovery Analytical Chemistry, Chemical Technologies, Wyeth Research, CN 8000, Princeton, NJ 08543, USA
    J Chromatogr A 1194:80-9. 2008
    ..1% concentration. On diol columns, the elution order of free primary, N-N-methyl, and N,N-dimethylamines was predictable, while the elution order of primary and secondary amines on cyano columns varied depending on ..
  68. ncbi Repulsion between inorganic particles inserted within surfactant bilayers
    Doru Constantin
    Laboratoire de Physique des Solides, Universite Paris Sud, CNRS, UMR8502, 91405 Orsay Cedex, France
    Phys Rev Lett 101:098101. 2008
    ..Systematic application of this technique should lead to a better understanding of the interaction between membrane inclusions...
  69. ncbi The L-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications
    Thomas Becker
    Department of Visceral and Transplant Surgery, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Nitric Oxide 20:61-7. 2009
    ..The importance of analytical chemistry in this area of research is also discussed in this article...
  70. ncbi Nitrosamine, dimethylnitramine, and chloropicrin formation during strong base anion-exchange treatment
    Jerome M Kemper
    Department of Chemical Engineering, Yale University, Mason Laboratory 313b, 9 Hillhouse Avenue, New Haven, Connecticut 06520, USA
    Environ Sci Technol 43:466-72. 2009
    ....
  71. ncbi A light-initiated, dark oxidation of bacteriochlorophyll from reaction center particles
    D C Brune
    Section of Genetics, Development and Physiology, Cornell University, Ithaca, NY 14850, USA
    Biochim Biophys Acta 333:37-43. 1974
    ..These results are consistent with the hypothesis that illumination generates a reaction initiator which is fairly stable in methanol but decays with a half-life of about 4.5 min in reaction center particles after illumination ceases...
  72. ncbi Optimization of the multiple enzymatic activities of the hepatitis C virus NS3 protein
    Shawn Misialek
    InterMune, Brisbane, CA 94005, USA
    Anal Biochem 394:138-40. 2009
    ..These conditions enable a particularly sensitive protease assay that uses picomolar concentrations of NS3...
  73. ncbi Mg2+-induced vesicles of tetradecyldimethylamine oxide and magnesium dodecyl sulfate
    Minmin Teng
    Key Laboratory of Colloid and Interface Chemistry of Ministry of Education, Shandong University, Jinan 250100, People s Republic of China
    J Colloid Interface Sci 338:537-41. 2009
    ..The results indicate that the crystal growth is along the (111) direction which can be affected by the presence of a vesicle phase having a fixation of Mg2+ ions to the bilayer membranes...
  74. ncbi Dimethylamine, trimethylamine, and biogenic amine formation in high-pressure processed semidried squid (Todarodes pacificius) during refrigerated storage
    Jingyu Gou
    Medical and Bio material Research Center and Div of Biomaterials Engineering, Kangwon Natl Univ, Chuncheon, Gangwon 200 701, Republic of Korea
    J Food Sci 75:M489-95. 2010
    ..The production of biogenic amines (BAs) varied with HPP treatment during refrigerated storage. Therefore, the application of HPP may provide a significant improvement in the safety and quality of semidried squid...
  75. ncbi Nitric oxide formation from hydroxylamine by myoglobin and hydrogen peroxide
    J Taira
    Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1336:502-8. 1997
    ..In summary, our results demonstrate a possible pathway of NO formation from HA, however, the significance of this mechanism for bioactivation of HA in vivo is unknown at the present time...
  76. ncbi Endotoxin adsorbent using dimethylamine ligands
    Zhi Yuan
    The State Key Laboratory of Functional Polymer Materials for Adsorption and Separation, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, Pepole s Republic of China
    Biomaterials 26:2741-7. 2005
    ..The combination of endotoxin with adsorbent was tight and adsorption capacity was effectually increased...
  77. ncbi N-nitrosodimethylamine formation by free-chlorine-enhanced nitrosation of dimethylamine
    Junghoon Choi
    Department of Civil and Environmental Engineering, University of Iowa, Iowa City, Iowa 52242 1527, USA
    Environ Sci Technol 37:4871-6. 2003
    ....
  78. ncbi Asymmetric synthesis of diarylmethyl amines by rhodium-catalyzed asymmetric addition of aryl titanium reagents to imines
    Tamio Hayashi
    Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan
    Angew Chem Int Ed Engl 43:6125-8. 2004
  79. ncbi Effects of non-ionic surfactants N-alkyl-N,N-dimethylamine-N-oxides on the structure of a phospholipid bilayer: small-angle X-ray diffraction study
    Janka Karlovska
    Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University, Bratislava SK 832 32, Slovak Republic
    Chem Phys Lipids 129:31-41. 2004
    ....
  80. ncbi The influence of detergents and amphiphiles on the solubility of the light-harvesting I complex
    M A Rosenow
    Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 1604, USA
    Acta Crystallogr D Biol Crystallogr 59:1422-8. 2003
    ..These results suggest that mass spectrometry can be used for screening of favorable crystallization conditions...
  81. ncbi Liquid-liquid phase separation of a surfactant-solubilized membrane protein
    Roberto Piazza
    INFM Politecnico di Milano, Dipartimento di Ingegneria Nucleare, Via Ponzio 34 3, I 20133 Milano, Italy
    Phys Rev Lett 90:208101. 2003
    ..After a fast initial droplet growth, the nearly arrested kinetics at a later stage leaves the system in a finely divided, long-lasting emulsified state...
  82. ncbi [Participation of dexamethasone and E and C vitamins in the modulation of the hepatotoxic effect induced by fomesafen and 2,4-D amino herbicides, in rats ]
    Luz Orfila
    , , Facultad de Farmacia Universidad Central de Venezuela, Caracas-Venezuela
    Acta Cient Venez 53:60-5. 2002
    ..Under experimental conditions of this study, the use of these agents does not guarantee protection against the hepatotoxic effects induced by the herbicides...
  83. ncbi Synthesis and inhibitory activity of dimethylamino-chalcone derivatives on the induction of nitric oxide synthase
    Javier Rojas
    , Universidad de Valencia, Facultad de Farmacia, , 46100 Burjassot, Valencia, Spain
    Eur J Med Chem 37:699-705. 2002
    ..Chalcone (6) at 25 mg kg(-1) by oral route, inhibited significantly the formation of oedema in the carrageenan-induced model of inflammation in mice...
  84. ncbi Inhibition and inactivation of the F1 adenosinetriphosphatase from Bacillus PS3 by dequalinium and activation of the enzyme by lauryl dimethylamine oxide
    S R Paik
    Department of Chemistry, University of California at San Diego, La Jolla 92093 0601
    Biochemistry 33:126-33. 1994
    ..When irradiated in the presence of dequalinium, TF1 is rapidly inactivated with an apparent Kd of 12.5 microM in the presence or absence of LDAO.(ABSTRACT TRUNCATED AT 250 WORDS)..
  85. ncbi Allergic contact dermatitis from shellac in mascara
    Christophe J Le Coz
    Unité de Dermato Allergologie, Dermatologie Professionnelle and Photobiologie, Clinique Dermatologique des Hôpitaux Universitaires de Strasbourg, France
    Contact Dermatitis 46:149-52. 2002
    ..These reports underline the rôle of networks, such as REVIDAL-GERDA, in monitoring the emergence of contact allergens and disseminating such information among the medical community...
  86. ncbi [Guanidino compounds and aliphatic monoamines in acute and chronic renal failure]
    Y Suzuki
    Internal Medicine II, Niigata University Medical School, Japan
    Nihon Jinzo Gakkai Shi 34:1077-85. 1992
    ..The liver homogenate produced DMA by adding TMA-N-O as substrate. However, the kidney homogenate could synthesize it even without substrate. Therefore, the kidney seems to be a major site of DMA production as well as the intestine...
  87. ncbi Wavelength shifts correlation between near infrared and ultraviolet regions of the LHII bacteriochlorophyll spectrum from Ectothiorhodospira sp
    A Buche
    Estacion Experimental de Aula Dei CSIC, Zaragoza, Spain
    Z Naturforsch C 56:363-8. 2001
    ..Both shifts have similar apparent pKs (12.3 and 12.6, respectively). Interestingly, the presence of NaCl reduces these pKs values to 11.4 and 11.7...
  88. ncbi Effects of 2,4-dichlorophenoxy acetic acid dimethyl amine salt on dental hard tissue formation in rats
    A R Alpoz
    Department of Pedodontics, Faculty of Dentistry, Ege University, Izmir, Turkey
    Environ Int 26:137-42. 2001
    ..It is concluded that environmental contaminants such as chlorinated organic pesticides may play an important role in infant's dental development when taken via mother's milk...
  89. ncbi Two mechanisms for toxic effects of hydroxylamines in human erythrocytes: involvement of free radicals and risk of potentiation
    C T Evelo
    Department of Pharmacology, Universiteit Maastricht, The Netherlands
    Blood Cells Mol Dis 24:280-95. 1998
    ..Since these enzymes play a key role in the protection of erythrocytes against oxidative stress a risk of potentiation during mixed exposure does exist...
  90. ncbi Activation and reaction kinetics of the dimethylamine/coenzyme M methyltransfer in Methanosarcina barkeri strain Fusaro
    R W Wassenaar
    Department of Microbiology, Faculty of Science, University of Nijmegen, The Netherlands
    Eur J Biochem 258:597-602. 1998
    ..barkeri Fusaro...
  91. ncbi 13C solid-state NMR of gramicidin A in a lipid membrane
    P O Quist
    Department of Physical Chemistry, Umea University, S 901 87 Umea, Sweden
    Biophys J 75:2478-88. 1998
    ..As expected, the elements of the residual chemical shift tensor were consistent with the single-stranded, right-handed beta6.3 helix structure proposed for gramicidin A in lipid membranes...
  92. ncbi Effects of N-alkyl-N,N-dimethylamine-N-oxides on the activity of purified sarcoplasmic reticulum Ca(2+)-transporting ATPase
    J Karlovska
    Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University, Bratislava, Slovakia
    Pharmazie 60:135-7. 2005
    ....
  93. ncbi Derivatization using dimethylamine for tandem mass spectrometric structure analysis of enzymatically and acidically depolymerized methyl cellulose
    Dane Momcilovic
    Department of Technical Analytical Chemistry, Lund University, P.O. Box 124, S-221 00 Lund, Sweden
    Anal Chem 77:2948-59. 2005
    ..The combination of DMA derivatization and tandem MS was demonstrated as a tool for the characterization of endoglucanase selectivity...
  94. ncbi UV photolytic mechanism of N-nitrosodimethylamine in water: dual pathways to methylamine versus dimethylamine
    Changha Lee
    School of Chemical Engineering, College of Engineering, Seoul National University, Sillim-dong, Gwanak-gu, Seoul 151-742, Korea
    Environ Sci Technol 39:2101-6. 2005
    ..The observed photolytic behaviors of NDMA photolysis could be successfully explained in terms of the new mechanism involving the role of NO2-...
  95. ncbi Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease
    Dimitrios Tsikas
    Institut fur Klinische Pharmakologie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 851:229-39. 2007
    ..17+/-4.2) being insignificantly lower (P=0.46). Between urinary DMA and ADMA there was a positive correlation (R=0.6655, P<0.0001) in coronary artery disease, but no correlation (R=0.27339) was found in end-stage liver disease...
  96. ncbi Ca2+- and ba2+-ligand coordinated unilamellar, multilamellar, and oligovesicular vesicles
    Aixin Song
    Key Laboratory of Colloid and Interface Chemistry, Shandong University, Ministry of Education, Jinan 250100, China
    Chemistry 13:496-501. 2007
    ..A mechanism is proposed that accounts for the formation of these new metal-ligand coordinated vesicles...
  97. ncbi Role of PKA and PKC in histamine H1 receptor-mediated activation of catecholamine neurotransmitter synthesis
    Nader H Moniri
    Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina, Chapel Hill, NC 25799-7360, USA
    Neurosci Lett 407:249-53. 2006
    ..Results for cis-PAB suggest H1/PLC/IP/DAG/PKC signaling activates PKA, downstream of cAMP formation, indicating apparent direct activation of PKA by PKC...
  98. ncbi Novel 5-dimethylamino-1- and 2-indanyl uracil derivatives
    Konstantin Ulanenko
    Global Innovative R and D, Teva Pharmaceutical Industries Ltd, Netanya 42504, Israel
    J Org Chem 71:7053-6. 2006
    ..The formation of 9 may be rationalized by a putative mechanism based on the intermediacy of the imminium methide species 8a...
  99. ncbi Short-chain aliphatic amines in human urine: a mathematical examination of metabolic interrelationships
    Stephen C Mitchell
    SORA Division, Biomolecular Medicine, Faculty of Medicine, Imperial College London, South Kensington, London SW7 2AZ, UK
    Metabolism 56:19-23. 2007
    ..In all cases, ethylamine was least significantly correlated with the other urinary components and appeared metabolically unrelated...
  100. ncbi A new amphoteric superabsorbent hydrogel based on sodium starch sulfate
    Gui Peng
    Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, Xinjiang University, Urumqi, Xinjiang, China
    Bioresour Technol 99:444-7. 2008
    ..The maximum swelling capacity in distilled water and saline solution reached 1493.1 and 91.0 g/g, respectively. These results were compared with those obtained from original starch-based hydrogel...
  101. ncbi Amphiphilic amine-N-oxides with aliphatic alkyl chain act as efficient superoxide dismutase mimics, antioxidants and lipid peroxidation blockers in yeast
    A Krasowska
    Institute of Genetics and Microbiology, Wrocław University, 51 148 Wrocław, Poland
    Folia Microbiol (Praha) 51:99-107. 2006
    ..sod mutants are useful in assessing pro- and antioxidant properties of different compounds...

Research Grants3

  1. Pyrrolysine, a novel genetically encoded amino acid
    Joseph Krzycki; Fiscal Year: 2007
    ..Finally, transposon mutagenesis will be used to identify unknown genes with anticipated or unanticipated functions during UAG translation as pyrrolysine. ..