butylamines

Summary

Top Publications

  1. ncbi Diacetylenic isobutylamides of Echinacea: synthesis and natural distribution
    Lankun Wu
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Phytochemistry 65:2477-84. 2004
  2. ncbi Caffeic acid derivatives production by hairy root cultures of Echinacea purpurea
    Chun Zhao Liu
    Phytochemical Engineering Group, National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    J Agric Food Chem 54:8456-60. 2006
  3. ncbi Rydberg fingerprint spectroscopy of hot molecules: structural dispersion in flexible hydrocarbons
    Michael P Minitti
    Department of Chemistry, Brown University, Providence, Rhode Island 02912, USA
    J Phys Chem A 110:10212-8. 2006
  4. ncbi Study of primary amines for nucleophilic cleavage of cyanylated cystinyl proteins in disulfide mass mapping methodology
    Jose Luis Gallegos-Perez
    Department of Chemistry, Michigan State University, East Lansing, MI 48824, USA
    Anal Biochem 346:311-9. 2005
  5. ncbi Application of colorimetric indicators and thermo-hand method to determine base permeation through chemical protective gloves
    Evanly Vo
    National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, Pennsylvania 15236, USA
    J Occup Environ Hyg 1:799-805. 2004
  6. ncbi Supercritical fluid extraction of alkylamides from Echinacea angustifolia
    Li Sun
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5
    J Agric Food Chem 50:3947-53. 2002
  7. ncbi Determination of tertiary amines based on pH junctions and field amplification in capillary electrophoresis with electrochemiluminescence detection
    Mallipattu Sreedhar
    Department of Chemistry, National Taiwan University, Taipei
    Electrophoresis 26:2984-90. 2005
  8. ncbi Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains
    Shigeki Sasaki
    Graduate School of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Biol Pharm Bull 27:531-7. 2004
  9. ncbi Environmentally friendly and highly sensitive ruthenium(II) tris(2,2'-bipyridyl) electrochemiluminescent system using 2-(dibutylamino)ethanol as co-reactant
    Xiaoqing Liu
    Department State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P R China
    Angew Chem Int Ed Engl 46:421-4. 2007
  10. ncbi Homochiral oligopeptides via a lattice-controlled polymerisation in racemic crystals of valine N-carboxyanhydride suspended in aqueous solutions
    Ran Eliash
    Department of Materials and Interfaces, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Chemistry 13:10140-51. 2007

Research Grants

  1. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 1999
  2. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2009
  3. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2002
  4. BIOSYNTHESIS AND METABOLISM OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 2001
  5. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2001
  6. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2000
  7. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2000
  8. BIOSYNTHESIS AND METABOLISM OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 2000
  9. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2000
  10. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 1999

Detail Information

Publications117 found, 100 shown here

  1. ncbi Diacetylenic isobutylamides of Echinacea: synthesis and natural distribution
    Lankun Wu
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Phytochemistry 65:2477-84. 2004
    ..angustifolia, E. sanguinea, E. simulata, E. tennesseensis, E. atrorubens and E. laevigata. The accumulation of these amides is sensitive to organ type and age...
  2. ncbi Caffeic acid derivatives production by hairy root cultures of Echinacea purpurea
    Chun Zhao Liu
    Phytochemical Engineering Group, National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    J Agric Food Chem 54:8456-60. 2006
    ..purpurea is possible. Furthermore, these hairy root cultures offer, for the very first time, an excellent biological model to study the biosynthetic pathway of medicinally important CADs...
  3. ncbi Rydberg fingerprint spectroscopy of hot molecules: structural dispersion in flexible hydrocarbons
    Michael P Minitti
    Department of Chemistry, Brown University, Providence, Rhode Island 02912, USA
    J Phys Chem A 110:10212-8. 2006
    ..A simple model accounts for the sensitivity of Rydberg fingerprint spectroscopy to the molecular shape, as well as the relative insensitivity of the spectra toward vibrational excitation...
  4. ncbi Study of primary amines for nucleophilic cleavage of cyanylated cystinyl proteins in disulfide mass mapping methodology
    Jose Luis Gallegos-Perez
    Department of Chemistry, Michigan State University, East Lansing, MI 48824, USA
    Anal Biochem 346:311-9. 2005
    ..Further, the concurrent use of homologous nucleophiles (e.g., ammonia and methylamine) facilitates recognition and identification of cleavage products...
  5. ncbi Application of colorimetric indicators and thermo-hand method to determine base permeation through chemical protective gloves
    Evanly Vo
    National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, Pennsylvania 15236, USA
    J Occup Environ Hyg 1:799-805. 2004
    ..The thermo-hand test method and base indicators together should find utility in detecting, collecting, and quantitatively analyzing base permeation samples under simulated in-use conditions...
  6. ncbi Supercritical fluid extraction of alkylamides from Echinacea angustifolia
    Li Sun
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5
    J Agric Food Chem 50:3947-53. 2002
    ..05) among those from fresh, ground and unground E. angustifolia roots. Supercritical fluid extraction therefore shows potential for the recovery of alkylamides from dried Echinacea roots...
  7. ncbi Determination of tertiary amines based on pH junctions and field amplification in capillary electrophoresis with electrochemiluminescence detection
    Mallipattu Sreedhar
    Department of Chemistry, National Taiwan University, Taipei
    Electrophoresis 26:2984-90. 2005
    ..The potential applicability of the new and low-cost CE-ECL system has been demonstrated by the determination of 1.0 microM lidocaine, a local anesthetic drug, in urine without any tedious sample preparation...
  8. ncbi Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains
    Shigeki Sasaki
    Graduate School of Pharmaceutical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Biol Pharm Bull 27:531-7. 2004
    ..The present findings indicate that none of these (11)C-labelled analogues have potential for PET study of binding sites on the N-methyl-D-aspartate (NMDA) receptors...
  9. ncbi Environmentally friendly and highly sensitive ruthenium(II) tris(2,2'-bipyridyl) electrochemiluminescent system using 2-(dibutylamino)ethanol as co-reactant
    Xiaoqing Liu
    Department State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P R China
    Angew Chem Int Ed Engl 46:421-4. 2007
  10. ncbi Homochiral oligopeptides via a lattice-controlled polymerisation in racemic crystals of valine N-carboxyanhydride suspended in aqueous solutions
    Ran Eliash
    Department of Materials and Interfaces, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Chemistry 13:10140-51. 2007
    ....
  11. ncbi Combining the enantioselectivities of L-valine diamide and permethylated beta-cyclodextrin in one gas chromatographic chiral stationary phase
    Pavel A Levkin
    Institute of Organic Chemistry, University of Tubingen, Germany
    Anal Chem 78:5143-8. 2006
    ..Furthermore, it was shown that the presence of the cyclodextrin selector in Chirasil-Val-C11 significantly improved the enantioseparation of proline, which represented a problematic amino acid on diamide CSPs...
  12. doi Concise synthesis of enantiomers of 4-aminobutane-1,2,3-triol
    NORMA K DUNLAP
    Department of Chemistry, Middle Tennessee State University, Murfreesboro, TN 37132, USA
    J Org Chem 73:2928-30. 2008
    ..A key step is the one-pot conversion of an aldehyde to an amide, the scope of which has been extended to include other carbohydrate-derived aldehydes...
  13. ncbi Indolebutylamines as selective 5-HT(1A) agonists
    Timo Heinrich
    Preclinical Pharmaceutical Research, Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany
    J Med Chem 47:4677-83. 2004
    ..3-[4-[4-(4-Methoxyphenyl)piperazin-1-yl]butyl]-1H-indole-5-carboxamide 45 is one of the most potent and selective 5-HT(1A) agonists known [5-HT(1A), IC(50) = 0.09 nM; D(2), IC(50) = 140 nM]...
  14. ncbi Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes
    A Matthias
    MediHerb Research Laboratories, Department of Chemistry, The University of Queensland, Brisbane, QLD 4072, Australia
    Chem Biol Interact 155:62-70. 2005
    ..These findings suggest that Echinacea may effect the P450-mediated metabolism of other concurrently ingested pharmaceuticals...
  15. ncbi Efficient transfection of DNA by liposomes formulated with cationic gemini amphiphiles
    Cecilia Bombelli
    Istituto di Metodologie Chimiche del CNR and Dipartimento di Chimica, Universita degli Studi di Roma La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy
    J Med Chem 48:5378-82. 2005
    ..Transfection efficiency was better than that obtained with a commercial lipofection kit...
  16. ncbi Developmental toxicity of oral n-butylamine hydrochloride and inhaled n-butylamine in rats
    A O Gamer
    Department of Product Safety, BASF Aktiengesellschaft, 67056 Ludwigshafen, Germany
    Food Chem Toxicol 40:1833-42. 2002
    ..Possible mechanisms of fetotoxicity are free radical production, metabolic acidosis, and lysosomotrophy...
  17. ncbi Novel enamine derivatives of 5,6-dihydro-2'-deoxyuridine formed in reductive amination of 5-formyl-2'-deoxyuridine
    Elzbieta Sochacka
    Institute of Organic Chemistry, Technical University of Lodz, Lodz, Poland
    Nucleosides Nucleotides Nucleic Acids 27:1045-60. 2008
    ....
  18. ncbi Maillard reaction of D-glucose: identification of a colored product with conjugated pyrrole and furanone rings
    Holger Lerche
    Department of Pharmacy, University of Munich, Butenandtstrasse 7, 81377 Munich, Germany
    J Agric Food Chem 50:2984-6. 2002
    ..The previously unknown, yellow product, 4-hydroxy-5-methyl-2-(N-butyl-3-hydroxy-5-(2-hydroxyethyl)pyrrolyl-2-methylidene)-2H-furan-3-one (1a), was isolated from the reaction mixtures and identified by spectroscopic data...
  19. ncbi PI factor, a novel type quorum-sensing inducer elicits pimaricin production in Streptomyces natalensis
    Eliseo Recio
    Instituto de Biotecnologia de Leon, Parque Cientifico de Leon, Avda del Real, n degrees 1, 24006 Leon, Spain
    J Biol Chem 279:41586-93. 2004
    ..Because restoration of pimaricin production in the npi287 mutant is conferred by both A-factor and PI factor, S. natalensis appears to be able to integrate different quorum signals from actinomycetes...
  20. ncbi Liquid chromatography quadrupole time-of-flight mass spectrometry analysis of carbosulfan, carbofuran, 3-hydroxycarbofuran, and other metabolites in food
    Carla Soler
    Laboratori de Bromatologia i Toxicologia, Facultat de Farmacia, Universitat de Valencia, Avenue Vicent Andres Estelles s n, 46100 Burjassot, Spain
    Anal Chem 79:1492-501. 2007
    ..Field degradation studies show that carbofuran, 3-hydroxycarbofuran, and dibutylamine are the main degradation products formed in the environmental disappearance of carbosulfan...
  21. ncbi Polyamines as olfactory stimuli in the goldfish Carassius auratus
    S H Rolen
    Department of Biological Sciences, Louisiana State University, Life Sciences Building Room 202, Baton Rouge, LA 70830, USA
    J Exp Biol 206:1683-96. 2003
    ..Behavioral assays indicated that polyamines are attractants that elicit feeding behavior similar to that elicited by L-amino acids...
  22. ncbi Water soluble cationic trans-platinum complexes which induce programmed cell death in the protozoan parasite Leishmania infantum
    Paul A Nguewa
    Departamento de Parasitologia, Facultad de Farmacia, Universidad de La Laguna, Tenerife, Spain
    J Inorg Biochem 99:727-36. 2005
    ..To the best of our knowledge, compounds 3 and 4 are the first reported trans-platinum complexes that show antiparasitic activity...
  23. ncbi Determination of isocyanates in air using 1-(2-methoxyphenyl)piperazine-impregnated filters: long-term sampling performance and field comparison with impingers with dibutylamine
    Carl J Sennbro
    Department of Occupational and Environmental Medicine, University Hospital, SE 221 85 Lund, Sweden
    Ann Occup Hyg 48:415-24. 2004
    ..For long-term monitoring the 2MP method can be applied for TDI but, since the method underestimates the concentrations, a correction factor is needed which needs to be corroborated further...
  24. ncbi A method of test for residual isophorone diisocyanate trimer in new polyester-polyurethane coatings on light metal packaging using liquid chromatography with tandem mass spectrometric detection
    Malcolm Driffield
    Central Science Laboratory, Department for Food Environment and Rural Affairs, Sand Hutton, York, UK
    J Chromatogr A 1141:61-6. 2007
    ....
  25. ncbi Development of a personal isocyanate sampler based on DBA derivatization on solid-phase microextraction fibers
    R Batlle
    Department of Analytical Chemistry, Stockholm University, Sweden
    Fresenius J Anal Chem 371:514-8. 2001
    ..Practical points that should be considered when using the SPME device as a diffusive sampler are discussed...
  26. ncbi Determination of airborne anhydrides using LC-MS monitoring negative ions of di-n-butylamine derivatives
    Jakob Dahlin
    Work Environment Chemistry, Analytical Chemistry, Stockholm University, P O B 460, S 281 24 Hässleholm, Sweden
    J Environ Monit 6:624-9. 2004
    ..When air samples were collected during thermal degradation of different coated metal sheets both anhydrides and isocyanates were present in the same samples and all the studied anhydrides were found...
  27. pmc AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana
    Andreas Meyer
    Institute of Plant Sciences, University of Bern, Altenbergrain 21, 3013 Bern, Switzerland
    J Biol Chem 281:7197-204. 2006
    ..In planta, AtGAT1 expression was highest in flowers and under conditions of elevated GABA concentrations such as wounding or senescence...
  28. ncbi Interaction of 2,3-dichloro-1,4-naphthoquinone with n-butylamine in halocarbon solvents
    Gururaj M Neelgund
    P G Department of Studies in Chemistry, Karnatak University, Dharwad 580003, India
    Spectrochim Acta A Mol Biomol Spectrosc 61:1729-35. 2005
    ..The influence of dielectric constant on the properties of reaction was discussed and the probable course of reaction is presented...
  29. ncbi High-performance ion-pair chromatographic behaviour of conjugated bile acids with di-n-butylamine acetate
    T Sasaki
    Department of Chemistry, College of Humanities and Sciences, Nihon University, Sakurajousui, Tokyo, Japan
    J Chromatogr A 888:93-102. 2000
    ..The present HPIPC method with DBAA provides an insight into the separation and structural elucidation of these biologically important bile acid conjugates and may be proved to be applied to HPLC-mass spectrometric analysis...
  30. ncbi Chemiluminescence associated with amino acid oxidation mediated by hypochlorous acid
    A Aspee
    Departmento de Ciencias Químicas, Facultad de Quimica y Biologia, Universidad de Santiago de Chile
    Luminescence 17:158-64. 2002
    ..The spectral changes and the effect of pH upon the observed luminescence are compatible with light emission from products produced in the free radical oxidation of Trp...
  31. ncbi Synthesis and characterization of model compounds of the lysine tyrosyl quinone cofactor of lysyl oxidase
    Minae Mure
    Department of Chemistry, University of California, Berkeley 94720 1460, USA
    J Am Chem Soc 125:6113-25. 2003
    ..Characterization of a 1,6-adduct between an o-quinone and butylamine (3-n-butylamino-5-ethyl-1,2-benzoquinone, 13) confirms the assignment of LTQ as a 1,4-addition product...
  32. ncbi Kinetic resolution of (R,S)-sec-butylamine using omega-transaminase from Vibrio fluvialis JS17 under reduced pressure
    Hyungdon Yun
    Laboratory of Molecular Biotechnology and Biomaterials, Institute for Molecular Biology and Genetics, Seoul National University, 151 742, Korea
    Biotechnol Bioeng 87:772-8. 2004
    ..0. Using the recombinant Escherichia coli BL21 overexpressing omega-TA, 400 mM racemic sec-butylamine was resolved successfully to 98% ee of (R)-sec-butylamine with 53% conversion at 150 torr and pH 7.0...
  33. ncbi Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test
    P Kelliher
    National University of Ireland, Department of Pharmacology, Galway, Ireland
    Psychoneuroendocrinology 28:332-47. 2003
    ..These results suggest that selective monoamine re-uptake inhibition produces distinct, but not necessarily exclusive, behavioural responses in the forced swim test...
  34. ncbi Cardiovascular pharmacological characterization of novel 2,3-dimethyl-2-butylamine derivatives in rats
    Yu Ping Chen
    Department of Cardiovascular Pharmacology, Beijing Institute of Pharmacology and Toxicology, 100850, PR China
    Life Sci 75:2131-42. 2004
    ....
  35. ncbi Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder
    Norifumi Sawada
    Department of Molecular Signaling, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi, Japan
    Lab Invest 88:553-63. 2008
    ..These results suggested that outlet obstruction caused ER stress via hypoxic stress in the bladder and that hypoxia-triggered ER stress may be involved in the induction of apoptosis in BOO...
  36. ncbi Mammalian spermidine synthase--identification of cysteine residues and investigation of the putrescine binding site--
    Hitomi Goda
    Faculty of Pharmaceutical Sciences, Josai University, 1 1 Keyakidai, Sakado, Saitama 350 0295, Japan
    Biol Pharm Bull 27:1327-32. 2004
    ..Our results indicated that 5-amino-1-pentene and 4MCHA possess comparable inhibitory activities towards the enzyme...
  37. ncbi A chemical chaperone 4-PBA ameliorates palmitate-induced inhibition of glucose-stimulated insulin secretion (GSIS)
    Sung E Choi
    Institute for Medical Science, Ajou University School of Medicine, Wonchon dong san 5, Youngtong Gu, Gyunggi Do, 442 749 Suwon, Republic of Korea
    Arch Biochem Biophys 475:109-14. 2008
    ..These data suggested that ER stress was involved in FFA-induced GSIS-inhibition and that the FFA-induced beta cell dysfunction could be ameliorated by treatment with a chemical chaperone...
  38. ncbi Effects of di-n-butylamine on the respiratory system of Wistar (WU) rats after subchronic inhalation
    Jochen Buschmann
    Fraunhofer Institut für Toxikologie und Experimentelle Medizin, Nikolai Fuchs Str 1, D 30625 Hannover, Germany
    Inhal Toxicol 15:701-13. 2003
    ....
  39. ncbi Towards automation of a valuable preclinical cardiac safety pharmacology assay: Evaluation of the effects of cardiac ion channel blockers on cardiac repolarisation in vitro
    Ian D Lightbown
    Global Safety Pharmacology Group, Drug Safety Research and Development, Pfizer Global Research and Development IPC 388, Ramsgate Road, Sandwich, Kent CT13 9NJ, United Kingdom
    J Pharmacol Toxicol Methods 56:194-202. 2007
    ..The throughput of compound testing in this assay is low therefore we designed a novel recording system to improve screening and animal tissue usage efficiencies...
  40. doi Development of a gas chromatography method for the estimation of alkylamines in foods
    Anji Pendem
    Unilever R and D, Bangalore, No 64, Main Road, Whitefield, Bangalore 560 066, India
    J Agric Food Chem 58:8904-10. 2010
    ..paper reports for the first time quantitative data on four alkylamines, ethyl-, propyl-, isopropyl-, and sec-butylamines, in commonly consumed fruits and vegetables...
  41. ncbi The "bridge" game: role of the fourth player in chiral recognition
    Caterina Fraschetti
    Dipartimento degli Studi di Chimica e Tecnologie del Farmaco, Universita di Roma La Sapienza, 00185 Roma, Italy
    Chemistry 17:3078-81. 2011
    ..Gas-phase experiments have indicated that at least a fourth "player" must be considered: the rigidity that a receptor opposes to distortions of its cavity resulting from noncovalent interactions with a chiral molecule (see picture)...
  42. doi Interaction of protonated merocyanine dyes with amines in organic solvents
    Eduardo Alberton Ribeiro
    Departamento de Quimica, Universidade Regional de Blumenau, FURB, Blumenau, SC, 89010 971, Brazil
    Spectrochim Acta A Mol Biomol Spectrosc 81:745-53. 2011
    ....
  43. doi Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy
    D Fu
    Harold Hamm Diabetes Center and Section of Endocrinology, University of Oklahoma Health Sciences Center, 1000 N Lincoln Blvd, Suite 2900, Oklahoma City, OK 73104, USA
    Diabetologia 55:3128-40. 2012
    ..In previous studies we have shown that extravasated, modified LDL is associated with pericyte loss, an early feature of diabetic retinopathy (DR). Here we sought to determine detailed mechanisms of this LDL-induced pericyte loss...
  44. doi Studies on the interaction mechanism of aminopyrene derivatives with human tumor-related DNA
    Li Li
    Jiangsu Key Laboratory of New Power Batteries, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    J Photochem Photobiol B 123:32-40. 2013
    ..PAGE results showed that the binding of amino-PAHs could further change the conformation of DNA sequences from the duplex to the antiparallel G-quadruplex...
  45. doi Epigenetic treatment of neurological disease
    Steven G Gray
    Translational Cancer Research Group, Department of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James s Hospital, James s Street, Dublin 8, Ireland
    Epigenomics 3:431-50. 2011
    ..Finally, some of the potential mechanisms to specifically target these proteins within the neurological setting are discussed...
  46. ncbi Fluorescence quenching of Rhodamine B base by two amines
    S Bakkialakshmi
    Department of Physics, Annamalai University, Annamalainagar 608 002, Tamil Nadu, India
    Spectrochim Acta A Mol Biomol Spectrosc 105:557-62. 2013
    ..The rate constants for the quenching process have been calculated using Stern-Volmer equation. Time resolved fluorescence study and (1)H NMR spectral study have also been carried out and discussed...
  47. doi An electrochemiluminescence sensor based on a Ru(bpy)3(2+)-silica-chitosan/nanogold composite film
    Zhi min Cai
    Department of Chemistry and Key Laboratory of Analytical Sciences of Xiamen University, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
    Talanta 94:356-60. 2012
    ..ECL studies revealed that the sensor had very good response to different concentrations of 2-(dibutylamino) ethanol. This sensor was also applied in methamphetamine determination...
  48. doi Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells
    Shaohua Zhu
    School of Pharmaceutical Sciences, Sun Yat Sen University, Guangzhou 510006, PR China
    Toxicol In Vitro 26:663-71. 2012
    ..Taken together, these results suggest that the ER stress response is involved in apoptosis induced by AAI in HK-2 cells, thus offering a new insight into the nephrotoxicity of AAI...
  49. ncbi Evaluating the role of curcum powder as a protective factor against bladder cancer--an experimental study
    Hala El-Mesallamy
    Biochemistry Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt
    Asian Pac J Cancer Prev 13:5287-90. 2012
    ..coli. These findings suggested that curcum may have a protective role during the process of bladder carcinogenesis by inhibiting the NF-κB pathway and its downstream products...
  50. ncbi Chemistry and some biological effects of model melanoidins and pigments as Maillard intermediates
    Fumitaka Hayase
    Department of Agricultural Chemistry, Meiji University, Kawasaki, Kanagawa, Japan
    Mol Nutr Food Res 50:1171-9. 2006
    ..1 cells, respectively. These findings suggest that melanoidins have suppressive effect on allergic reaction as a novel physiological effect...
  51. doi Structure-activity relationships for hepatocyte toxicity and electrophilic reactivity of alpha,beta-unsaturated esters, acrylates and methacrylates
    Katie Chan
    University of Toronto, Faculty of Pharmacy, Toronto, ON, Canada
    J Appl Toxicol 28:1004-15. 2008
    ..These results suggest that differences in hepatocyte toxicity of acrylates and methacrylates can be related to their electrophilic reactivity which corresponds to their ability to deplete GSH and protein thiols...
  52. ncbi Pharmacokinetics and metabolism of 3,4-dichlorophenyl-propenoyl-sec.-butylamine in rats by high performance liquid chromatography-ion trap mass spectrometry
    Shu Mei Wang
    Department of Pharmacology, Basic Medical School, Beijing University, 38 Xue Yuan Road, Beijing 100083, China
    J Chromatogr B Analyt Technol Biomed Life Sci 850:92-100. 2007
    ..It was concluded that 3,4-DCPB was involved in the multiple metabolic pathways (hydrolysis, dealkylation and oxidation) and the hydrolysis product, 3,4-dichloro-cinnamic acid (M1) appeared to be the major metabolite...
  53. ncbi Analysis of pharmacological effects of drugs used for treatment of urinary disturbance based on anticholinergic and smooth muscle-relaxing effects
    Risa Takayanagi
    Department of Clinical Evaluation of Drug Efficacy, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
    Biol Pharm Bull 30:1297-300. 2007
    ..01 to 0.48%. The present results suggest that muscarinic acetylcholine receptor occupancy is a principal determinant of the therapeutic effect of a drug used for treatment of urinary disturbance...
  54. ncbi Electrophilic reactions of skin-sensitizing sultones
    David W Roberts
    Unilever Research Port Sunlight, Quarry Road East, Bebington, Wirral, CH63 3JW, United Kingdom
    Chem Res Toxicol 20:61-71. 2007
    ....
  55. ncbi Preparation of convection interaction media isobutyl disc monolithic column and its application to purification of secondary alcohol dehydrogenase and alcohol oxidase
    Kimiyasu Isobe
    Department of Agro bioscience, Iwate University, Ueda 3 18 8, Morioka 020 8550, Japan
    J Chromatogr A 1144:85-9. 2007
    ..P-AOD was also purified to an electrophoretically homogeneous state by three column chromatographies of CIM DEAE-8 tube, CIM C4-8 tube and CIM isobutyl disc columns...
  56. ncbi Determination of aliphatic amines using fluorescence intensity of 4-methyl umbelliferone
    M R Hadjmohamadi
    Department of Chemistry, University of Mazandaran, Babolsar, Iran
    Spectrochim Acta A Mol Biomol Spectrosc 70:358-61. 2008
    ..Determination of amines at fluorescence enhancing region using inverse fluorescence intensity against inverse amine concentration (bireciprocal plot) were investigated and related equations was also proposed...
  57. doi Ultrafast dynamics of epicocconone, a second generation fluorescent protein stain
    Soumit Chatterjee
    Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney NSW 2109, Australia
    J Phys Chem A 115:10154-8. 2011
    ..The correct interpretation of these data will allow the design of second generation protein stains based on the epicocconone scaffold with increased quantum yields and photostability...
  58. ncbi Modification of neodymium-doped ZnO hybrid nanoparticles under mild hydrothermal conditions
    Behzad Shahmoradi
    Faculty of Environmental Health Engineering, Kurdistan University of Medical Sciences, Sanandaj 66174, Iran
    Nanoscale 2:1160-4. 2010
    ..The work proved the efficiency of caprylic acid and n-butylamine as suitable surfactants for surface modification of neodymium-doped ZnO hybrid nanoparticles...
  59. ncbi Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile
    Sankar K Guchhait
    Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research NIPER, S A S Nagar Mohali 160062, Punjab, India
    Org Biomol Chem 8:3631-4. 2010
    ....
  60. ncbi Reactivity of the insecticide fenitrothion toward O and N nucleophiles
    Natalia M Rougier
    Instituto de Investigaciones en Fisicoquimica de Cordoba INFIQC, Departamento de Quimica Organica, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Medina Allende y Haya de la Torre, Argentina
    J Org Chem 75:3427-36. 2010
    ..With HOO(-), NH(2)OH, and NH(2)O(-) a significant alpha-effect was observed, confirming the participation of the nucleophile in the rate-limiting step of the reaction...
  61. doi Dual-sensitive probe 1-imidazole-2-(5-benzoacridine)-ethanone for the determination of amines in environmental water using HPLC with fluorescence detection and online atmospheric chemical ionization-mass spectrometry identification
    Jinmao You
    Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining 810001, PR China
    Talanta 80:1392-9. 2010
    ..Therefore, the facile IBAE intermediate derivatization allowed the development of a highly sensitive and specific method for the quantitative analysis of trace levels of amines in environmental water...
  62. doi Study of highly efficient bimetallic ruthenium tris-bipyridyl ECL labels for coreactant system
    Shiguo Sun
    State Key Laboratory of Fine Chemicals, Dalian University of Technology, No 158 40, Zhongshanlu, Xigang District 116012, Dalian, China
    Anal Chem 81:10227-31. 2009
    ..This is the highest ECL detection limit for bimetallic system reported until now. The study provides a general methodology to further improve and tune the ECL efficiency by using multimetallic ruthenium complexes...
  63. pmc Effect of the regiochemistry of butyl amide substituents on the solution-state structures of lanthanide(III) DOTA-tetraamide complexes
    Tomoyasu Mani
    Department of Chemistry, University of Texas at Dallas, 800 W Campbell Road, Richardson, Texas 75080, USA
    Inorg Chem 48:10338-45. 2009
    ..Unlike chiral complexes with larger amide substituents there is no "locking" effect of the orientation of the pendant arms in these complexes and up to four diastereoisomeric coordination isomers can be observed...
  64. doi Synthesis and antifungal activity of beta-trifluoroalkyl aminovinyl ketone derivatives
    Gary Gellerman
    Department of Biological Chemistry, Ariel University Center of Samaria, Ariel 40700, Israel
    J Agric Food Chem 57:8303-7. 2009
    ..We propose that (Z)-3-amino-4,4,4-trifluoro-1-phenylbut-2-en-1-one is the minimal structural requirement for a beta-trifluoroalkyl aminovinyl ketone fungitoxic derivative...
  65. doi Machine learning of chemical reactivity from databases of organic reactions
    Gonçalo V S M Carrera
    REQUIMTE, CQFB, Departamento de Quimica, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829 516 Caparica, Portugal
    J Comput Aided Mol Des 23:419-29. 2009
    ..While NaCNBH3 is a selective reducing reagent widely used in organic synthesis, BuNH2 is a nucleophile that mimics the reactivity of the lysine side chain (involved in an initiating step of the mechanism leading to skin sensitization)...
  66. pmc Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases
    Dale E Edmondson
    Department of Biochemistry, Emory University, Atlanta, Georgia 30322, USA
    Biochemistry 48:4220-30. 2009
    ..This review summarizes the current structural and mechanistic information available that can be utilized in the development of future highly specific neuroprotectants and cardioprotectants...
  67. doi Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol, a compound designed to act as a beta2 adrenoceptor agonist
    Marvin A Soriano-Ursúa
    Departamento de Bioquimica, Instituto Politecnico Nacional, Plan de San Luis y Diaz Miron, DF Mexico, Mexico
    Eur J Med Chem 44:2840-6. 2009
    ..Additionally, propranolol and ICI 118,551 showed competitive antagonism in relation to the relaxing effect of the test compound (pA(2) 6.204+/-0.367 and 9.089+/-0.470, respectively)...
  68. doi Inhibition of cough-reflex sensitivity by benzonatate and guaifenesin in acute viral cough
    Peter V Dicpinigaitis
    Albert Einstein College of Medicine and Montefiore Medical Center, 1825 Eastchester Road, Bronx, NY 10461, USA
    Respir Med 103:902-6. 2009
    ..008). The mechanism by which the combination of B+G causes a potentiation of antitussive effect remains to be elucidated. Our results suggest that B+G may be an effective therapy for acute cough due to the common cold (URI)...
  69. pmc Amine-reactive fluorene probes: synthesis, optical characterization, bioconjugation, and two-photon fluorescence imaging
    Alma R Morales
    Department of Chemistry, The College of Optics and Photonics, University of Central Florida, P O Box 162366, Orlando, Florida 32816 2366, USA
    Bioconjug Chem 19:2559-67. 2008
    ..Conventional and 2PFM imaging and fluorescence lifetime imaging (FLIM) of HeLa, NT2, and H1299 cells, incubated with two-photon absorbing amine-reactive probe (1), RGDfK-dye conjugate (7), and Reelin-dye conjugate (6), was demonstrated...
  70. pmc Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B
    Erika M Milczek
    Department of Chemistry, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, USA
    J Med Chem 51:8019-26. 2008
    ..A mechanism to explain these structural and spectral data is proposed...
  71. doi Application of structure-activity relationships to investigate the molecular mechanisms of hepatocyte toxicity and electrophilic reactivity of alpha,beta-unsaturated aldehydes
    Katie Chan
    University of Toronto, Faculty of Pharmacy, Toronto, ON, Canada
    J Appl Toxicol 28:1027-39. 2008
    ..Even with the presence of electrophile characteristics, alpha,beta-unsaturated aldehyde hepatocyte toxicity could not be predicted exclusively by electrophilic reactivity as oxidative metabolism was also a factor for toxicity...
  72. doi Dual buffer gases for ion manipulation in a miniature ion trap mass spectrometer with a discontinuous atmospheric pressure interface
    Tsung Chi Chen
    Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA
    Rapid Commun Mass Spectrom 25:3274-80. 2011
    ..The buffer gas can be switched between air and helium for different steps within a single scan, which allows further optimization of the instrument performance for tandem mass spectrometry...
  73. ncbi Practical synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate and resolution of enantiomers
    Qun Xu
    Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, DHHS, 9000 Rockville Pike, Bethesda, Maryland 20892, USA
    J Org Chem 71:8655-7. 2006
    ..The route provides ready access to multigram quantities of both enantiomers without the need for chromatography...
  74. ncbi Soybean and ascorbate feeding in experimental carcinogenesis: immunological studies
    A M Medhat
    Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt
    Tumori 77:372-8. 1991
    ..These agents were found to be capable of increasing the defense mechanism of rats by enhancing both cellular and humoral immunity in the presence of the carcinogenic nitrosamine precursors dibutylamine and sodium nitrite...
  75. ncbi Hydrolysis triggers oxidation of a trans diamine platinum(II) anticancer complex
    Ana María Pizarro
    Facultad de Ciencias, Departamento de Quimica Inorganica, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Angew Chem Int Ed Engl 42:5339-42. 2003
  76. ncbi Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells
    Hong Wang
    Division of Rheumatology, Department of Internal Medicine and Interdisciplinary Group in Immunology, University of Iowa College of Medicine, Iowa City, IA 52442, USA
    J Immunol 170:3696-706. 2003
    ..Thus, recognition of nonpeptide prenyl pyrophosphate, bisphosphonate, and alkylamine Ags is conserved in primates suggesting that primates can provide an animal model for human gammadelta T cell Ag responses...
  77. ncbi Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in atherogenesis in KKAy diabetic mice fed with high cholesterol diet
    P H Yu
    Neuropsychiatry Research Unit, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Diabetologia 45:1255-62. 2002
    ..The deaminated products include the toxic aldehydes, formaldehyde and methylglyoxal, respectively, hydrogen peroxide and ammonia...
  78. ncbi Comparison of the omega-transaminases from different microorganisms and application to production of chiral amines
    J S Shin
    School of Chemical Engineering and Institute for Molecular Biology and Genetics, Seoul National University, Korea
    Biosci Biotechnol Biochem 65:1782-8. 2001
    ..fluvialis JS17. Enantiomeric excess of (R)-sec-butylamine reached 94.7% after 12 h of reaction...
  79. ncbi Characterization of a model compound for the lysine tyrosylquinone cofactor of lysyl oxidase
    M Akagawa
    Department of Applied Bioorganic Chemistry, Division of Life Science, Graduate School of Agricultural Science, Tohoku University, 1 1 Tsutsumidori Amamiyamachi, Aobaku, Sendai, 981 8555, Japan
    Biochem Biophys Res Commun 281:193-9. 2001
    ..0. In the presence of beta-aminopropionitrile and upon deoxygenation with N2 aldelyde, production was decreased. The important features of the reaction were consistent with the enzymatic reaction...
  80. ncbi LY393615, a novel neuronal Ca(2+) and Na(+) channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischemia
    M J O'Neill
    Lilly Research Centre Ltd, Erl Wood Manor, Windlesham, GU20 6PH, Surrey, UK
    Brain Res 888:138-149. 2001
    ..The compound is neuroprotective when administered post-occlusion and may therefore be a useful anti-ischaemic agent...
  81. ncbi Do amines react with protonated peptides in the gas phase via transacylation reactions to induce peptide bond cleavage?
    R A O'Hair
    School of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia
    Rapid Commun Mass Spectrom 14:1707-16. 2000
    ..MS(4) experiments, carried out to determine the nature of the [b(n) + BuNH(2)](+) ions, reveal that they correspond to a mixture of hydrogen bonded (i.e. proton bound dimer) and covalent amide bond structures...
  82. pmc CYP2D6 and CYP2C19 genotypes of patients with terodiline cardiotoxicity identified through the yellow card system
    G A Ford
    Department of Pharmacological Sciences, University of Newcastle upon Tyne, UK
    Br J Clin Pharmacol 50:77-80. 2000
    ..We sought to determine whether CYP2D6 (debrisoquine hydroxylase) or CYP2C19 (S-mephenytoin hydroxylase) status is a risk factor for terodiline cardiotoxicity...
  83. ncbi Benzonatate overdose associated with seizures and arrhythmias
    B I Crouch
    University of Utah, Salt Lake City, USA
    J Toxicol Clin Toxicol 36:713-8. 1998
    ..Therefore, laboratory analysis of benzonatate is difficult. We report 2 cases of benzonatate poisoning with seizures and cardiac arrest and an analytical method to identify and quantify benzonatate in human plasma...
  84. ncbi Cross-linking of proteins by Maillard processes--model reactions of D-glucose or methylglyoxal with butylamine and guanidine derivatives
    M O Lederer
    Institut fur Lebensmittelchemie, Universitat Hohenheim, Stuttgart, Germany
    Bioorg Med Chem 6:993-1002. 1998
    ..It seems justified, therefore, to expect cross-linking of proteins by action of reducing carbohydrates to proceed analogously...
  85. ncbi Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors
    A P Tamiz
    Department of Chemistry, University of Oregon, Eugene, Oregon 97403, USA
    J Med Chem 41:3499-506. 1998
    ..This study provides a framework for designing structurally novel NR2B-selective antagonists which may be useful for treatment of a variety of neurological disorders...
  86. ncbi Increase of formation of methylamine and formaldehyde in vivo after administration of nicotine and the potential cytotoxicity
    P H Yu
    Department of Psychiatry, University of Saskatchewan, Saskatoon, Canada
    Neurochem Res 23:1205-10. 1998
    ..The findings support the idea that nicotine can enhance SSAO/methylamine-mediated increase of formaldehyde and oxidative stress and this could in part contribute the adverse effect of health associated with smoking...
  87. ncbi ATP-dependent lysis of isolated lysosomes by basic substances and acidic ionophores
    S Ohkuma
    Department of Molecular and Cell Biology, Faculty of Pharmaceutical Sciences, Kanazawa University, Ishikawa, Japan
    Cell Struct Funct 22:253-68. 1997
    ..Furthermore, this lysosomal disruption was inhibited by cytosolic factors. This phenomenon will provide an in vitro system for studies on osmoregulation and the intracellular dynamics of the lysosomal system, including membrane fusion...
  88. ncbi A microgonotropen branched decaaza decabutylamine and its DNA and DNA/transcription factor interactions
    T C Bruice
    Department of Chemistry, University of California, Santa Barbara 93106, USA
    Bioorg Med Chem 5:685-92. 1997
    ..Results of studies of the inhibition of the binding of several proteins to target DNA are discussed. Binding of the E2F1 transcription factor to its DNA target is 50% inhibited at approximately 2 nM concentration of 8...
  89. ncbi Ion chromatography of amylamine and tert.-butylamine in pharmaceuticals
    N K Jagota
    Analytical R and D, Bristol-Myers Squibb, Pharmaceutical Research Institute, New Brunswick, NJ 08903-0191, USA
    J Chromatogr A 739:343-9. 1996
    ..9993). The method for TBA was linear from 5 to 30% (w/w) (50-300 micrograms/ml, n = 8, r = 0.9993) of working sample concentration (1 mg/ml BMS-188 494-04). The precision and accuracy of the methods are presented...
  90. ncbi [Anticholinergic therapy of urinary incontinence and urinary frequency associated with the elderly--with special reference to dementia]
    T Sugiyama
    Department of Urology, Kinki University School of Medicine
    Nihon Hinyokika Gakkai Zasshi 84:1068-73. 1993
    ..This suggests that the major cause of incontinence in demented patients is not the bladder dysfunction but the specific conditions of demented patients such as agnosia and apraxia...
  91. ncbi The effect of terodiline on hyperreflexia (in vivo) and the in vitro response of isolated strips of rabbit bladder to field stimulation, bethanechol and KCL
    R M Levin
    Division of Urology, University of Pennsylvania School of Medicine, Philadelphia 19104
    Pharmacology 46:346-52. 1993
    ....
  92. ncbi Contact guidance induced organization of extracellular matrix
    Michael E Manwaring
    The Keck Center for Tissue Engineering, Department of Bioengineering, University of Utah, 20 South 2030 East, Building 570, Room 108D, Salt Lake City, UT 84112, USA
    Biomaterials 25:3631-8. 2004
    ....
  93. ncbi 4-Aryl(benzyl)amino-4-heteroarylbut-1-enes as building blocks in heterocyclic synthesis. 4. Synthesis of 4, 6-dimethyl-5-nitro(amino)-2-pyridylquinolines and their antiparasitic activities
    Vladimir V Kouznetsov
    Laboratory of Fine Organic Synthesis, Research Center for Biomolecules, School of Chemistry, Industrial University of Santander, Bucaramanga, Colombia
    Arch Pharm (Weinheim) 337:127-32. 2004
    ..Although some of the compounds showed only moderate activity it was possible to establish some structure-activity relationships...
  94. ncbi 2,5-Dihydroxybenzoic acid butylamine and other ionic liquid matrixes for enhanced MALDI-MS analysis of biomolecules
    Marko Mank
    Numico Research Germany, Bahnstrasse 14 30, 61318 Friedrichsdorf, Germany
    Anal Chem 76:2938-50. 2004
    ..This was proven by the desialylation of sialylactose with sialidase from Clostridium perfringens in the presence of diluted aqueous DHBB and subsequent direct MALDI-MS analysis of the reaction mixture...
  95. ncbi From experiment to theory: molecular orbital parameters to interpret the skin sensitization potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one
    Aynur O Aptula
    School of Pharmacy and Chemistry, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, England
    Chem Res Toxicol 18:324-9. 2005
    ..A key finding of this analysis is that the reaction produces "positive chlorine" in the form of N-chloro- and/or N,N-dichloro-butylamine, which could contribute to the skin sensitizing properties of MCI...
  96. ncbi Interaction of gemini surfactants butane-1,4-diyl-bis(alkyldimethylammonium bromide) with DNA
    Daniela Uhrikova
    Faculty of Pharmacy, Comenius University, Odbojarov 10, 832 32 Bratislava, Slovak Republic
    Colloids Surf B Biointerfaces 42:59-68. 2005
    ..The aggregates undergo structural changes induced by temperature in the range 60-95 degrees C, which are accompanied by changes of the diffraction patterns, namely in the region of reciprocal spacing s=0.15-0.30 nm(-1)...
  97. ncbi Solvent-free sampling with di-n-butylamine for monitoring of isocyanates in air
    Asa Marand
    Work Environment Chemistry, Stockholm University, PO Box 460, S 281 24 Hässleholm, Sweden
    J Environ Monit 7:335-43. 2005
    ..In conclusion, the solvent-free sampler is a convenient alternative in most applications to the more cumbersome impinger-filter sampler...
  98. ncbi Effects of amine modifiers on the separation of tetramethylrhodamine-labeled mono- and oligosaccharides by capillary zone electrophoresis
    H D Osthoff
    Department of Chemistry, University of Alberta, Edmonton, Canada
    J Chromatogr A 895:285-90. 2000
    ..The separation was significantly improved in the presence of the organic modifiers methyl- and ethylamines, but worsened in the presence of propyl- and butylamines. Possible mechanisms of the amine additives are discussed.
  99. ncbi Microbial synthesis of chiral amines by (R)-specific transamination with Arthrobacter sp. KNK168
    A Iwasaki
    Life Science Research Laboratories, Life Science RD Center, Corporate Research and Development Division, Kaneka Corporation, 1 8, Miyamae machi, Takasago cho, Takasago, Hyogo, 676 8688, Japan
    Appl Microbiol Biotechnol 69:499-505. 2006
    ..knk168...
  100. ncbi A novel HPLC procedure for detection and quantification of aminoacetone, a precursor of methylglyoxal, in biological samples
    Michael Kazachkov
    Neuropsychiatry Research Unit, Department of Psychiatry, University of Saskatchewan, A114 Medical Research Building, 103 Wiggins Road, Saskatoon, Sask, Canada
    J Chromatogr B Analyt Technol Biomed Life Sci 824:116-22. 2005
    ..Results confirm that aminoacetone is an endogenous substrate for SSAO. However, data also indicate that deamination is not the only catabolic pathway for aminoacetone...
  101. ncbi New 6-butylamino-6-deoxycellulose and 6-deoxy-6-pyridiniumcellulose derivatives with highest regioselectivity and completeness of reaction
    Chun Liu
    ITMC, Institute of Technical Chemistry and Macromolecular Chemistry, Hemocompatible and Biocompatible Biomaterials, University of Technology Aachen, Worringer Weg 1, D 52074 Aachen, Germany
    Carbohydr Res 340:2229-35. 2005
    ..The highest regioselectivity and completeness at C-6 can be obtained at 100 degrees C for 90 h, whereas at 145 degrees C substitution also occurs at C-2. The results were proved by 1H NMR and 13C NMR spectroscopy...

Research Grants61

  1. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 1999
    ....
  2. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2009
    ..The MAO B inhibitors would function as neuroprotective agents for the prevention of and treatment of age-related neurological disorders. The MAO A inhibitors could have clinical benefit as new types of anti-depressants. ..
  3. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2002
    ..abstract_text> ..
  4. BIOSYNTHESIS AND METABOLISM OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 2001
    ..The potential use of the CmaA gene for construction of hybrid peptide antibiotics containing L-alloisoleucine or coronamic acid will also be explored, using surfactin biosynthesis in B. subtilis as a model system. ..
  5. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2001
    ..The final goal is to overproduce and study the sulfur insertion and dioxygenase proteins in vitro. ..
  6. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2000
    ....
  7. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2000
    ....
  8. BIOSYNTHESIS AND METABOLISM OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 2000
    ..The potential use of the CmaA gene for construction of hybrid peptide antibiotics containing L-alloisoleucine or coronamic acid will also be explored, using surfactin biosynthesis in B. subtilis as a model system. ..
  9. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2000
    ..The final goal is to overproduce and study the sulfur insertion and dioxygenase proteins in vitro. ..
  10. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 1999
    ....
  11. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2002
    ..The final goal is to overproduce and study the sulfur insertion and dioxygenase proteins in vitro. ..
  12. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2001
    ....
  13. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2009
    ..The MAO B inhibitors would function as neuroprotective agents for the prevention of and treatment of age-related neurological disorders. The MAO A inhibitors could have clinical benefit as new types of anti-depressants. ..
  14. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2008
    ..The MAO B inhibitors would function as neuroprotective agents for the prevention of and treatment of age-related neurological disorders. The MAO A inhibitors could have clinical benefit as new types of anti-depressants. ..
  15. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2007
    ..The MAO B inhibitors would function as neuroprotective agents for the prevention of and treatment of age-related neurological disorders. The MAO A inhibitors could have clinical benefit as new types of anti-depressants. ..
  16. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2007
    ..Future investigations of sparsomycin will focus on cloning the sparsomycin resistance gene from S. sparsogenes to understand the mechanism of self-resistance in this organism and to gain access to the biosynthetic genes. ..
  17. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2006
    ..The MAO B inhibitors would function as neuroprotective agents for the prevention of and treatment of age-related neurological disorders. The MAO A inhibitors could have clinical benefit as new types of anti-depressants. ..
  18. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2006
    ..Future investigations of sparsomycin will focus on cloning the sparsomycin resistance gene from S. sparsogenes to understand the mechanism of self-resistance in this organism and to gain access to the biosynthetic genes. ..
  19. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2005
    ..abstract_text> ..
  20. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2005
    ..Future investigations of sparsomycin will focus on cloning the sparsomycin resistance gene from S. sparsogenes to understand the mechanism of self-resistance in this organism and to gain access to the biosynthetic genes. ..
  21. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2004
    ..abstract_text> ..
  22. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2004
    ..Future investigations of sparsomycin will focus on cloning the sparsomycin resistance gene from S. sparsogenes to understand the mechanism of self-resistance in this organism and to gain access to the biosynthetic genes. ..
  23. BIOSYNTHESIS OF SOME MICROBIAL METABOLITES
    Ronald Parry; Fiscal Year: 2003
    ..The final goal is to overproduce and study the sulfur insertion and dioxygenase proteins in vitro. ..
  24. COVALENT FLAVIN COENZYME IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 2003
    ..abstract_text> ..
  25. Peptidomimetics of D-Ala-D-Ala as Novel Antibacterials
    Norma Dunlap; Fiscal Year: 2003
    ..This would have a significant impact in the ability to treat bacterial infections. ..
  26. COVALENT FLAVIN COENZYMES IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 1991
    ..The results of these studies will be of importance in mitochondrial electron transport and in the elucidation of the mechanism of action of important enzyme systems such as succinate dehydrogenase and monoamine oxidase...
  27. BIOSYNTHESIS AND METABOLISM OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 1999
    ..The potential use of the CmaA gene for construction of hybrid peptide antibiotics containing L-alloisoleucine or coronamic acid will also be explored, using surfactin biosynthesis in B. subtilis as a model system. ..
  28. BIOSYNTHESIS OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 1992
    ..Polyoximic acid is a component of the polyoxins, a group of antifungal antibiotics produced by S. cacaoi var. asoensis...
  29. COVALENT FLAVIN COENZYMES IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 1990
    ..The results of these studies will be of importance in mitochondrial electron transport and in the elucidation of the mechanism of action of important enzyme systems such as succinate dehydrogenase and monoamine oxidase...
  30. COVALENT FLAVIN COENZYMES IN FLAVOENZYME CATALYSIS
    Dale Edmondson; Fiscal Year: 1993
    ..Anti- depressants used clinically are MAO A inhibitors while the clinical use of MAO B inhibitors is to potentiate L-Dopa therapy of patients with Parkinson's Disease...
  31. BIOSYNTHESIS OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 1993
    ..Polyoximic acid is a component of the polyoxins, a group of antifungal antibiotics produced by S. cacaoi var. asoensis...
  32. BIOSYNTHESIS OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 1991
    ..Future investigations of coronatine bio- synthesis will employ precursor incorporation experiments to probe both the mechanism of assembly of the polyketide and the mechanism of cyclopropane ring formation...
  33. BIOSYNTHESIS OF CYCLOPENTANOIDS
    Ronald Parry; Fiscal Year: 1990
    ..Future investigations of coronatine bio- synthesis will employ precursor incorporation experiments to probe both the mechanism of assembly of the polyketide and the mechanism of cyclopropane ring formation...