sulfaquinoxaline

Summary

Summary: An antiprotozoal agent used to combat coccidial infections of swine, cattle, fowl, and other veterinary animals. Also used in controlling outbreaks of fowl typhoid and fowl cholera and in treatment of infectious enteritis.

Top Publications

  1. ncbi Sulfaquinoxaline inhibition of vitamin K epoxide and quinone reductase
    P C Preusch
    Department of Chemistry, University of Akron, Ohio 44325
    Arch Biochem Biophys 269:18-24. 1989
  2. ncbi Simultaneous determination of 17 sulfonamides and the potentiators ormetoprim and trimethoprim in salmon muscle by liquid chromatography with tandem mass spectrometry detection
    Ross A Potter
    Canadian Food Inspection Agency, Dartmouth Laboratory, PO Box 1060, Dartmouth, NS, B3B 1Y9, Canada
    J AOAC Int 90:343-8. 2007
  3. ncbi Determination of dimetridazole and ipronidazole in feeds at cross-contamination levels
    D D Hughes
    Food and Drug Administration, Kansas City, MO 64106
    J Assoc Off Anal Chem 71:474-7. 1988
  4. ncbi Interaction between lead toxicity and some sulphonamides in rabbits: effect on certain blood constituents and serum enzymes
    M Atef
    Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
    Dtsch Tierarztl Wochenschr 101:187-90. 1994
  5. ncbi Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection
    Marcello Di Sabatino
    University of Bologna, Department of Pharmaceutical Sciences, Via Belmeloro 6, 40126 Bologna, Italy
    J AOAC Int 90:598-603. 2007
  6. doi Determination of sulfonamides in soil samples based on alumina-coated magnetite nanoparticles as adsorbents
    Lei Sun
    College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, Jilin 130012, China
    Anal Chim Acta 665:185-92. 2010
  7. doi Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC-UV detection
    Lei Sun
    College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China
    Chemosphere 77:1306-12. 2009
  8. doi Use of capillary electrophoresis with laser-induced fluorescence detection to screen and liquid chromatography-tandem mass spectrometry to confirm sulfonamide residues: validation according to European Union 2002/657/EC
    Rodrigo Barcellos Hoff
    Programa de Pós Graduação em Biologia Celular e Molecular, Centro de Biotecnologia do Estado do Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    J Chromatogr A 1216:8254-61. 2009
  9. doi Synthesis, crystal structure and fluorescence spectrum of a cadmium(II) sulfaquinoxaline complex
    Xiu hua Zhao
    Faculty of Science, Ningbo University, Ningbo, Zhejiang 315211, People s Republic of China
    Acta Crystallogr C 69:1332-5. 2013
  10. ncbi Detection limits of antimicrobials in ewe milk by delvotest photometric measurements
    R L Althaus
    Departamento de Ciencia Animal, Universidad Politecnica de Valencia, Camino de Vera, 14 Apartado 22012, 46071 Valencia, Espana
    J Dairy Sci 86:457-63. 2003

Scientific Experts

Detail Information

Publications81

  1. ncbi Sulfaquinoxaline inhibition of vitamin K epoxide and quinone reductase
    P C Preusch
    Department of Chemistry, University of Akron, Ohio 44325
    Arch Biochem Biophys 269:18-24. 1989
    b>Sulfaquinoxaline (N1-(2-quinoxalinyl)sulfanilamide) has been shown to be a potent (Ki = 1 microM) freely reversible inhibitor of the dithiothreitol-dependent reduction of both vitamin K epoxide and vitamin K quinone by rat liver ..
  2. ncbi Simultaneous determination of 17 sulfonamides and the potentiators ormetoprim and trimethoprim in salmon muscle by liquid chromatography with tandem mass spectrometry detection
    Ross A Potter
    Canadian Food Inspection Agency, Dartmouth Laboratory, PO Box 1060, Dartmouth, NS, B3B 1Y9, Canada
    J AOAC Int 90:343-8. 2007
    ..sulfamethazine (SMZ), sulfamethoxypyridazine (SMP), sulfamonomethoxine (SMM), sulfachloropyridazine (SCP), sulfaquinoxaline (SQX), and sulfadimethoxine (SDM)] and 2 potentiators [ormetoprim (OMP) and trimethoprim (TMP)] in fish ..
  3. ncbi Determination of dimetridazole and ipronidazole in feeds at cross-contamination levels
    D D Hughes
    Food and Drug Administration, Kansas City, MO 64106
    J Assoc Off Anal Chem 71:474-7. 1988
    ..Carbadox, furazolidone, levamisole, oxytetracycline, chlortetracycline, sulfamethazine, sulfaquinoxaline, arsanilic acid, piperazine, penicillin, and commonly added vitamins and minerals do not interfere...
  4. ncbi Interaction between lead toxicity and some sulphonamides in rabbits: effect on certain blood constituents and serum enzymes
    M Atef
    Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
    Dtsch Tierarztl Wochenschr 101:187-90. 1994
    ..On the other hand, AST/ALT ratio in both healthy and lead intoxicated rabbits was found to decrease 1 h after the last dose as compared with before treatment...
  5. ncbi Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection
    Marcello Di Sabatino
    University of Bologna, Department of Pharmaceutical Sciences, Via Belmeloro 6, 40126 Bologna, Italy
    J AOAC Int 90:598-603. 2007
    ..sulfadimidine, sulfamethizole, sulfamonomethoxine, sulfachloropyridazine, sulfadoxine, sulfadimethoxine, and sulfaquinoxaline. The residues were extracted with acetone-chloroform (1 + 1)...
  6. doi Determination of sulfonamides in soil samples based on alumina-coated magnetite nanoparticles as adsorbents
    Lei Sun
    College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, Jilin 130012, China
    Anal Chim Acta 665:185-92. 2010
    ..sulfamethoxazole (SMX), sulfamonomethoxine (SMM), sulfamethoxydiazine (SMD), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX) in different soil samples based on magnetic solid-phase extraction (MSPE)...
  7. doi Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC-UV detection
    Lei Sun
    College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China
    Chemosphere 77:1306-12. 2009
    ..SAs) compounds including sulfamethoxazole (SMX), sulfamethoxydiazine (SMD), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX) from environmental water samples...
  8. doi Use of capillary electrophoresis with laser-induced fluorescence detection to screen and liquid chromatography-tandem mass spectrometry to confirm sulfonamide residues: validation according to European Union 2002/657/EC
    Rodrigo Barcellos Hoff
    Programa de Pós Graduação em Biologia Celular e Molecular, Centro de Biotecnologia do Estado do Rio Grande do Sul, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    J Chromatogr A 1216:8254-61. 2009
    ..for determining six sulfonamides (SAs) (sulfadiazine, sulfathiazole, sulfamethazine, sulfamethoxazole, sulfaquinoxaline and sulfadimethoxine) in liver by a capillary electrophoresis screening method and a liquid chromatography ..
  9. doi Synthesis, crystal structure and fluorescence spectrum of a cadmium(II) sulfaquinoxaline complex
    Xiu hua Zhao
    Faculty of Science, Ningbo University, Ningbo, Zhejiang 315211, People s Republic of China
    Acta Crystallogr C 69:1332-5. 2013
    ..Cd(II) cation has a distorted octahedral coordination geometry formed by five N atoms from three different sulfaquinoxaline ligands and one O atom from a water molecule...
  10. ncbi Detection limits of antimicrobials in ewe milk by delvotest photometric measurements
    R L Althaus
    Departamento de Ciencia Animal, Universidad Politecnica de Valencia, Camino de Vera, 14 Apartado 22012, 46071 Valencia, Espana
    J Dairy Sci 86:457-63. 2003
    ..oxytetracycline; 590, tetracycline; 88, sulfadiazine; 44, sulfamethoxazole; 140, sulfametoxypyridazine; 48, sulfaquinoxaline; 12,000, chloramphenicol; and 290, trimethoprim...
  11. ncbi Analysis of veterinary drug residues in shrimp: a multi-class method by liquid chromatography-quadrupole ion trap mass spectrometry
    Hui Li
    U S Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD 20708, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 836:22-38. 2006
    ..This method is able to confirm oxytetracycline residues at 200 ng/g, toltrazuril sulfone at 50 ng/g, sulfaquinoxaline at 20 ng/g, and the other 15 drugs at 10 ng/g or lower levels...
  12. doi Development and validation of an LC-UV method for the determination of sulfonamides in animal feeds
    P Kumar
    Department de Química Analítica, Universitat de Barcelona, Spain
    Drug Test Anal 4:368-75. 2012
    ..eight sulfonamides (sulfachloropyridazine, sulfadiazine, sulfadimidine, sulfadoxine, sulfamethoxypyridazine, sulfaquinoxaline, sulfamethoxazole, and sulfadimethoxine) in six types of animal feed...
  13. doi Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives
    Mostafa M Ghorab
    Medicinal, Aromatic and Poisonous Plants Research Center MAPPRC, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
    Acta Pharm 61:415-25. 2011
    ..This paper reports the synthesis of novel thioureido sulfaquinoxaline derivatives...
  14. doi Simultaneous detection of sulfamethazine and sulfaquinoxaline using a dual-label time-resolved fluorescence immunoassay
    Tao Le
    College of Life Science, Chongqing Normal University, Chongqing, PR China
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:1264-9. 2013
    ..fluoroimmunoassay (TRFIA) was introduced for the simultaneous quantification of sulfamethazine (SM2) and sulfaquinoxaline (SQX)...
  15. doi Rapid and sensitive determination of sulfonamide residues in milk and chicken muscle by microfluidic chip electrophoresis
    Lili Wang
    State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, Department of Chemistry, Lanzhou University, Lanzhou, Gansu, China
    J Agric Food Chem 60:1613-8. 2012
    ..By optimizing these conditions, the separation of four sulfonamides, sulfamethazine, sulfamethoxazole, sulfaquinoxaline, and sulfanilamide, was achieved within 1 min with limits of detection (S/N = 3) of 0.2-2...
  16. doi Synthesis, in-vitro anticancer screening and radiosensitizing evaluation of some new N-(quinoxalin-2-yl)benzenesulfonamide derivatives
    M M Ghorab
    Department of Drug Radiation Research, National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt
    Arzneimittelforschung 62:46-52. 2012
    The objective of this work is to synthesize and investigate the anticancer activity of a new series of sulfaquinoxaline derivatives by incorporating biologically active moieties (thiourethane, thiazole, imidazole, imidazopyrimidine, ..
  17. doi Dispersive liquid-liquid microextraction combined with ultra-high performance liquid chromatography for the simultaneous determination of 25 sulfonamide and quinolone antibiotics in water samples
    Antonio V Herrera-Herrera
    Departamento de Quimica Analitica, Nutricion y Bromatologia, Facultad de Quimica, Universidad de La Laguna, Avenida Astrofísico Francisco Sánchez, S N, 38206 La Laguna Tenerife, Spain
    J Pharm Biomed Anal 75:130-7. 2013
    ..sulfadimidin, sulfamethoxypyridazine, sulfadoxine, sulfamethoxazole, sulfisoxazole, sulfadimethoxine and sulfaquinoxaline) and 14 quinolones (pipemidic acid, marbofloxacin, fleroxacin, levofloxacin, pefloxacin, ciprofloxacin, ..
  18. doi Evaluation and validation of two microbiological tests for screening antibiotic residues in honey according to the European guideline for the validation of screening methods
    V Gaudin
    Community Reference Laboratory, Anses Fougères, La Haute Marche BP 90203, F 35302 Fougeres Cedex, France
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:234-43. 2013
    ..gt;75 µg kg(-1)), sulfamethoxazole (≤25 µg kg(-1)), sulfanilamide (>>1000 µg kg(-1)), sulfaquinoxaline (>75 µg kg(-1)), sulfathiazole (≤250 µg kg(-1)) and lincomycin (>1500 µg kg(-1))...
  19. doi Development and validation of a confirmatory method for the determination of sulphonamides in milk by liquid chromatography with diode array detection
    Valentina Gamba
    Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna, B Ubertini, Via Bianchi 9, 25124 Brescia, Italy
    Anal Chim Acta 637:18-23. 2009
    ..sulfadiazine, sulfapyridine, sulfamerazine, sulfamethazine, sulfamonomethoxine, sulfadimethoxine and sulfaquinoxaline) in milk samples was developed and validated...
  20. ncbi Trace determination of sulfonamides residues in meat with a combination of solid-phase microextraction and liquid chromatography-mass spectrometry
    Kuan Hui Lu
    Department of Chemistry, National Chung Hsing University, Taichung, Taiwan, ROC
    Talanta 72:1082-7. 2007
    ..STZ), sulfamerazine (SMR), sulfamethazine (SMT), sulfamonomethoxine (SMMX), sulfamethoxazole (SMXZ), sulfaquinoxaline (SQX) and sulfadimethoxine (SDMX), were investigated in this study...
  21. doi The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim
    Marco De Liguoro
    Department of Public Health, Comparative Pathology and Veterinary Hygiene, Faculty of Veterinary Medicine, University of Padua, Agripolis, I 35020 Legnaro PD, Italy
    Chemosphere 75:1519-24. 2009
    ..86 mgL(-1)). In acute binary tests SMZ showed a complex interaction with sulfaquinoxaline (superadditivity, additivity or subadditivity) at the three different combination ratios tested, simple ..
  22. doi A landmark contribution to poultry science--prophylactic control of coccidiosis in poultry
    H D Chapman
    Department of Poultry Science, University of Arkansas, Fayetteville 72701, USA
    Poult Sci 88:813-5. 2009
    Continuous feeding of low concentrations of sulfaquinoxaline for the control of coccidiosis in poultry" by L. C. Grumbles, J. P. Delaplane, and T. C. Higgins [Poult. Sci...
  23. doi History of the discovery of sulfaquinoxaline as a coccidiostat
    William C Campbell
    Research Institute for Scientists Emeriti, Drew University, Madison, New Jersey 07901, USA
    J Parasitol 94:934-45. 2008
    b>Sulfaquinoxaline played an important part in the demotion of roast chicken from vaunted Sunday-dinner status to an unrespected position on the everyday menu of the Western world...
  24. doi Use of experimental design and effective mobility calculations to develop a method for the determination of antimicrobials by capillary electrophoresis
    Mónica Cecília Vargas Mamani
    Institute of Chemistry, Department of Analytical Chemistry, University of Campinas UNICAMP, P O Box 6154, 13084 971 Campinas, SP, Brazil
    Talanta 76:1006-14. 2008
    ..chloramphenicol (CLP), danofloxacin (DANO), ciprofloxacin (CIPRO), enrofloxacin (ENRO), sulfamethazine (SMZ), sulfaquinoxaline (SQX) and sulfamethoxazole (SMX) is described...
  25. doi Simultaneous analysis of 16 sulfonamide and trimethoprim antibiotics in environmental waters by liquid chromatography-electrospray tandem mass spectrometry
    Hong Chang
    College of Urban and Environmental Sciences, Peking University, Beijing 100871, China
    J Chromatogr A 1190:390-3. 2008
    ..08 (sulfadimethoxine)-161 ng/L (sulfapyridine) in wastewater and 10 (0.03 (sulfamethizol)-8.9 ng/L (sulfaquinoxaline) in river samples were detected.
  26. doi Application of liquid-liquid-liquid microextraction and high-performance liquid-chromatography for the determination of sulfonamides in water
    Che Yi Lin
    Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan
    Anal Chim Acta 612:37-43. 2008
    ..method also confirms microextraction to be robust to monitoring trace levels of sulfacetamide, sulfadiazine, sulfathiazole, sulfamerazine, sulfadimidine, sulfamonomethoxine, sulfamethoxazole, and sulfaquinoxaline in aqueous samples.
  27. ncbi [Simultaneous determination of nine sulfonamide residues in milk using solid phase extraction and high performance liquid chromatography]
    Yinliang Wu
    Quality Control and Inspection Center for Domestic Animal Products, Ministry of Agriculture, Beijing 100026, China
    Se Pu 25:728-31. 2007
    ..sulfamethoxypyridazine, sufamonomethoxine, sulfachloropyridazine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline) in milk was developed...
  28. ncbi [Determination of 12 sulfonamides in cosmetics by ultra performance liquid chromatography]
    Hehui Zheng
    Beijing Center for Disease Prevention and Control, Beijing 100013, China
    Se Pu 25:238-40. 2007
    ..sulfamethoxazole, sulfadiazine, sulfisoxazole, sulfathiazole, sulfadi-methoxine, sulfamerazine, sulfaquinoxaline, sulfamethazine, sulfanitran) in cosmetics was developed by ultra performance liquid chromatography with ..
  29. ncbi Determination of residues of sulphonamide in eggs and laying hens
    Shazia Tabassum
    Department of Chemistry GC University Faisalabad, Pakistan
    Pak J Pharm Sci 20:199-202. 2007
    ..In another experiment, a group of hens were kept at a poultry farm after medicating them with darvisal liquid to see if the residues of sulphonamide pass into the eggs of poultry. The period of existence of residues was noted...
  30. doi Determination of ten sulphonamides in egg by liquid chromatography-tandem mass spectrometry
    A F Forti
    Istituto Zooprofilattico Sperimentale dell Abruzzo e del Molise G Caporale, Via Campo Boario, 64100 Teramo, Italy
    Anal Chim Acta 637:214-9. 2009
    ..sulfamethoxypyridazine, sulfachloropyridazine, sulfamethoxazole, sulfamonomethoxine, sulfadimethoxine and sulfaquinoxaline) in egg by liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed...
  31. doi Analytical method for simultaneous determination of pesticide and veterinary drug residues in milk by CE-MS
    Cristina Blasco
    Laboratori de Bromatologia, Facultat de Farmacia, Universitat de Valencia, Burjassot, Valencia, Spain
    Electrophoresis 30:1698-707. 2009
    ..of veterinary drugs (ciprofloxacin, enrofloxacin, sulfacetamide, sulfabenzamide, sulfachlorpyridazine, sulfaquinoxaline, sulfathiazole, sulfisoxazole), whose contents are regulated by the EU Council Regulations no...
  32. doi Kinetic modelling and residue depletion of drugs in eggs
    P Hekman
    Medicines Evaluation Board, Veterinary Medicines Unit, Den Haag, The Netherlands
    Br Poult Sci 52:376-80. 2011
    ..The model could be used as a tool to obtain an insight into those properties of a drug which are responsible for the amount of residue in eggs, and could help in the design of critical studies for determining withdrawal periods for eggs...
  33. doi Fast and selective extraction of sulfonamides from honey based on magnetic molecularly imprinted polymer
    Ligang Chen
    College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China
    J Agric Food Chem 57:10073-80. 2009
    ..including sulfadiazine, sulfamerazine, sulfamethoxydiazine, sulfamonomethoxine, sulfadimethoxine, sulfamethoxazole and sulfaquinoxaline in different honey samples. The recoveries of SAs in these samples from 67.1% to 93.6% were obtained.
  34. ncbi Development of a quantitative multiclass/multiresidue method for 21 veterinary drugs in shrimp
    Hui Li
    U S Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD 20708, USA
    J AOAC Int 94:394-406. 2011
    ..sulfonamides (sulfadiazine, sulfamerazine, sulfamethazine, sulfachloropyridazine, sulfadimethoxine, and sulfaquinoxaline); tetracyclines (oxytetracycline, tetracycline, and chlortetracycline); (fluoro)quinolones (norfloxacin, ..
  35. doi Occurrence and source apportionment of sulfonamides and their metabolites in Liaodong Bay and the adjacent Liao River basin, North China
    Ai Jia
    Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing, China
    Environ Toxicol Chem 30:1252-60. 2011
    ..4%) were the main chemicals from human sources, while sulfamonomethoxine, sulfamethazine, sulfaquinoxaline, sulfaguanidine, sulfadiazine, sulfanilamide, and sulfamethoxypyridazine were dominant in the animal ..
  36. doi Occurrence of veterinary antibiotics in animal wastewater and surface water around farms in Jiangsu Province, China
    Ruicheng Wei
    Jiangsu Provincial Key Laboratory of Animal Derived Food Safety, Nanjing 210014, China
    Chemosphere 82:1408-14. 2011
    ..63 μg L(-1) for sulfadoxine, 39.5 μg L(-1) for doxycycline and 0.64 μg L(-1) for sulfaquinoxaline were determined in the collected samples...
  37. doi Multiresidue analysis of sulfonamides in meat by supramolecular solvent microextraction, liquid chromatography and fluorescence detection and method validation according to the 2002/657/EC decision
    Esther María Costi
    Department of Analytical Chemistry, Faculty of Sciences, University of Cordoba, Edificio Anexo Marie Curie, Campus de Rabanales, 14071 Cordoba, Spain
    J Chromatogr A 1217:6250-7. 2010
    ..sulfamethoxypyridazine, sulfachloropyridazine, sulfadoxine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline) in animal muscle tissues (pork, chicken, turkey, lamb and beef) at concentrations below the maximum residue ..
  38. doi Utilizing three monoclonal antibodies in the development of an immunochromatographic assay for simultaneous detection of sulfamethazine, sulfadiazine, and sulfaquinoxaline residues in egg and chicken muscle
    Yancheng Guo
    State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, P R China
    Anal Chem 82:7550-5. 2010
    ..was developed and validated for simultaneous detection of sulfamethazine (SM(2)), sulfadiazine (SDZ), and sulfaquinoxaline (SQX) in chicken breast muscle and egg samples...
  39. doi Studies on the extraction of sulfonamides from agricultural soils
    J Raich-Montiu
    Departament de Quimica Analitica, Universitat de Barcelona, Marti i Franques 1, 08028, Barcelona, Spain
    Anal Bioanal Chem 397:807-14. 2010
    ..of six sulfonamides (sulfadiazine, sulfadimidine, sulfathiazole, sulfachloropiridazine, sulfadimethoxine, and sulfaquinoxaline) from soils with different physicochemical characteristics and at several aging times was investigated...
  40. doi Comparison of several extraction techniques for multiclass analysis of veterinary drugs in eggs using ultra-high pressure liquid chromatography-tandem mass spectrometry
    Antonia Garrido Frenich
    Group Analytical Chemistry of Contaminants, Department of Analytical Chemistry, Almeria University, E 04071 Almeria, Spain
    Anal Chim Acta 661:150-60. 2010
    ..The solvent extraction procedure was validated, obtaining recoveries ranging from 60% (sulfaquinoxaline) to 119% (levamisole) with repeatability values (expressed as relative standard deviations, RSDs) lower than ..
  41. doi Evaluation of the aquatic toxicity of two veterinary sulfonamides using five test organisms
    Marco De Liguoro
    Dipartimento di Sanita Pubblica, Patologia Comparata e Igiene Veterinaria, Facolta di Medicina Veterinaria, Universita degli Studi di Padova, Agripolis, I 35020 Legnaro, PD, Italy
    Chemosphere 81:788-93. 2010
    The aquatic toxicity of sulfaquinoxaline (SQO) and sulfaguanidine (SGD) was evaluated on the following test organisms: Daphnia magna (reproduction test), Pseudokirchneriella subcapitata, Scenedesmus dimorphus, Synecococcus leopoliensis (..
  42. doi On-line coupling of dynamic microwave-assisted extraction to solid-phase extraction for the determination of sulfonamide antibiotics in soil
    Ligang Chen
    College of Chemistry, Jilin University, Changchun 130012, China
    Anal Chim Acta 648:200-6. 2009
    ..for the determination of sulfonamides (SAs) including sulfadiazine, sulfameter, sulfamonomethoxine and sulfaquinoxaline in soil...
  43. doi Rapid separation and highly sensitive detection methodology for sulfonamides in shrimp using a monolithic column coupled with BDD amperometric detection
    Haruthai Sangjarusvichai
    Department of Chemistry, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok 10330, Thailand
    Talanta 79:1036-41. 2009
    ..sulfaguanidine, sulfadiazine, sulfamethazine, sulfamonomethoxine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline)...
  44. doi A confirmatory method for the simultaneous extraction, separation, identification and quantification of Tetracycline, Sulphonamide, Trimethoprim and Dapsone residues in muscle by ultra-high-performance liquid chromatography-tandem mass spectrometry accord
    Mark McDonald
    Central Meat Control Laboratory, Department of Agriculture, Backweston Campus, Celbridge, Co Kildare, Ireland
    J Chromatogr A 1216:8110-6. 2009
    ..sulfamethoxypyridazine, sulfamonomethoxine, sulfachlorpyridazine, dapsone, sulfamethoxazole, sulfisoxazole, sulfaquinoxaline and sulfadimethoxine. Samples are extracted with 0...
  45. doi Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin
    Huan Yu
    MOA Key Laboratory of Food Safety Evaluation National Reference Laboratory of Veterinary Drug Residues HZAU, Huazhong Agricultural University, Wuhan, Hubei 430070, China
    J Chromatogr B Analyt Technol Biomed Life Sci 879:2653-62. 2011
    ..sulfachloropyridazine, sulfamethoxazole, sulfamonomethoxine, sulfadoxine, sulfaclozine, sulfadimethoxine, sulfaquinoxaline in the muscles, livers and kidneys of swine, bovine and chicken were developed and validated...
  46. ncbi Validation of an analytical method to determine sulfamides in kidney by HPLC-DAD and PARAFAC2 with first-order derivative chromatograms
    I Garcia
    Department of Chemistry, Faculty of Sciences, Pza Misael Banuelos s n, 09001 Burgos, Spain
    Anal Chim Acta 587:222-34. 2007
    ..HPLC-DAD): sulfadiazine, sulfamethazine, sulfamethoxypyridazine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline. Two main difficulties arose in identifying and quantifying the analytes...
  47. ncbi Multiresidue supercritical fluid extraction method for the recovery at low ppb levels of three sulfonamides from fortified chicken liver
    R J Maxwell
    U S Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, Wyndmoor, PA 19038, USA
    J Chromatogr B Biomed Sci Appl 715:431-5. 1998
    ..High recoveries of sulfamethazine (SMZ), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX) were obtained from chicken liver samples fortified at levels from 1000 to 50 ppm.
  48. ncbi Transferring profile of dietary sulphaquinoxaline into eggs
    N Furusawa
    Faculty of Human Life Science, Osaka City University, Japan
    Zentralbl Veterinarmed A 45:225-8. 1998
    ..After 4 days of SQ feeding, the SQ content in the homogenized eggs reached a plateau at 0.0292.x (= 0.007318.4x) ppm. This equation permits to predict SQ content in the eggs...
  49. ncbi Decreasing profile of residual sulphaquinoxaline in eggs
    N Furusawa
    Faculty of Human Life Science, Osaka City University, Japan
    Br Poult Sci 39:241-4. 1998
    ..4. Biological half-life of SQ in the whole egg was estimated to be 1.23 d. 5. From the above equation, SQ residue of whole egg laid at 9th d after withdrawal will be below the detection limit of 0.01 mg/kg...
  50. pmc Monodrug efficacies of sulfonamides in prophylaxis for Pneumocystis carinii pneumonia
    W T Hughes
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    Antimicrob Agents Chemother 40:962-5. 1996
    ..and sulfadimethoxine per kg per day, as little as 10 mg of sulfameter, sulfachlorpyridazine, and sulfaquinoxaline per kg per day; and 100 mg of sulfaguanidine and sulfanilamide per kg per day...
  51. ncbi Comparison of supercritical CHF3 and CO2 and methanol-modified CHF3 and CO2 for extraction of sulfonamides from chicken liver
    M Ashraf-Khorassani
    Virginia Polytechnic Institute and State University, Department of Chemistry, Blacksburg 24061, USA
    J AOAC Int 79:1043-9. 1996
    ....
  52. ncbi Kinetic behaviour of sulphaquinoxaline and amprolium in chickens
    M G El-Sayed
    Pharmacology Department, Fac of Vet Med Moshtohor, Benha
    Dtsch Tierarztl Wochenschr 102:481-5. 1995
    ..11 +/- 0.14 h respectively. Sulphaquinoxaline and its N4 acetyl metabolite disappeared from all body tissues at 120 hours, however amprolium persisted in most tissues for 72 hours after the last dose of repeated administrations...
  53. ncbi Comparative plasma and tissue pharmacokinetics and drug residue profiles of different chemotherapeutants in fowls and rabbits
    T Li
    Pharmacology and Toxicology Program, Northeast Agricultural University, Harbin, China
    J Vet Pharmacol Ther 18:260-73. 1995
    ..Ceftriaxone (CEF), intravenously at 50 mg/kg, sulfamonomethoxine (SMM) and sulfaquinoxaline (SQ), orally at 200 mg/kg, and olaquindox (OLA), orally at 50 mg/kg, were administered to young broilers...
  54. ncbi Stability of sulfaquinoxaline, sulfadimethoxine, and their N4-acetyl derivatives in chicken tissues during frozen storage
    O W Parks
    U S Department of Agriculture, Eastern Regional Research Center, Agricultural Research Service, Philadelphia, PA 19118
    J AOAC Int 77:486-8. 1994
    The N4-acetyl derivatives of sulfaquinoxaline and sulfadimethoxine were stable in fortified chicken liver and thigh muscle tissues during frozen storage for 1 year at -20 and -70 degrees C...
  55. ncbi Confirmation of sulfonamide residues in kidney tissue by liquid chromatography-mass spectrometry
    S Porter
    Analytical Chemistry Unit, Central Veterinary Laboratory, Addlestone, Surrey, UK
    Analyst 119:2753-6. 1994
    ..Although sulfonamides can be determined using a single quadrupole mass spectrometer with pseudo-MS-MS, advantages in interfacing to a tandem mass spectrometer are demonstrated...
  56. ncbi Experimental and field sulfaquinoxaline toxicosis in Leghorn chickens
    B M Daft
    University of California, Davis
    Avian Dis 33:30-4. 1989
    Mortality of 47% occurred in a commercial flock of 20-week-old leghorn pullets treated with 0.05% sulfaquinoxaline in the feed. The drug was given for 2-3 days, removed for 2 days, and fed again for 2-3 days...
  57. ncbi Immunosuppressive properties of chloroquinoxaline sulfonamide
    R F Branda
    Department of Medicine, University of Vermont, Burlington 05401
    Biochem Pharmacol 38:3521-6. 1989
    ..In all of these drug effects, CQS was approximately one to two logs more potent than the parent compound, sulfaquinoxaline (SQ). These studies indicate that CQS inhibits essential basic processes in human lymphocytes...
  58. ncbi Tissue sulfonamide concentration and correlation in turkeys
    R L Epstein
    USDA, Food Safety and Inspection Service, Chemistry Division, Washington, DC 20250
    Am J Vet Res 50:926-8. 1989
    Nineteen hen turkeys (10 to 12 kg each) were used in a feeding study to determine sulfadimethoxine and sulfaquinoxaline concentrations in blood serum, liver, and skeletal muscle, as well as the respective ratios at selected withdrawal ..
  59. ncbi Chemotherapy of caecal coccidiosis: efficacy of toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate, given in drinking water, against field isolates of Eimeria tenella
    H D Chapman
    Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire
    Res Vet Sci 46:419-20. 1989
    ..Few oocysts of E tenella were produced in birds medicated with sulphaquinoxaline/pyrimethamine or amprolium/ethopabate and none in those medicated with toltrazuril...
  60. ncbi Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts
    A Arakawa
    Department of Veterinary Science, College of Agriculture, University of Osaka Prefecture, Japan
    Vet Parasitol 38:55-60. 1991
    ..Monensin, salinomycin, lasalocid, amprolium plus ethpabate, amporolium plus ethopabate plus sulfaquinoxaline, clopidol, or nicarbazin were given to chickens continuously via the feed at the recommended use level or one-..
  61. ncbi Tissue concentrations of sulphaquinoxaline administered in the food of laying hens
    N Furusawa
    Faculty of Human Life Science, Osaka City University, Osaka, Japan
    Br Poult Sci 39:683-5. 1998
    ..4. The plateau values of SQ in the tissues were much greater than those of sulphamonomethoxine and sulphadimethoxine...
  62. ncbi Tissue residues of some sulphonamides in normal and Eimeria stiedai infected rabbits
    A H Atta
    Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
    Dtsch Tierarztl Wochenschr 106:295-8. 1999
    ..1 g/g) in the liver and kidney and lower levels in other tissues. A withdrawal period of 4 days for SDZ and 5 days for SDD and SQ in healthy rabbits and 7 days for SDZ and 8 days for SDD and SQ in E. stiedai infected rabbits is suggested...
  63. ncbi Multiresidue determination of sulfonamides in edible catfish, shrimp and salmon tissues by high-performance liquid chromatography with postcolumn derivatization and fluorescence detection
    Theresa A Gehring
    Division of Biochemical Toxicology, U S Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR 72079, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 840:132-8. 2006
    ..sulfachloropyridazine (SCP), sulfamonomethoxine, sulfadoxine, sulfamethoxazole, sulfadimethoxine (SDM), and sulfaquinoxaline (SQX)) residues in edible catfish, shrimp and salmon tissues was developed and validated at 5, 10 or 20 ng g(-..
  64. ncbi [Determination of residual sulfonamides in meat by high performance liquid chromatography with solid-phase extraction]
    Yan Zhang
    College of Science, China Agricultural University, Beijing 100094, China
    Se Pu 23:636-8. 2005
    ..such as sulfamethazine (SM2), sulfamonomethoxine (SMM), sulfamethiazole (SMZ), sulfadimethoxine (SDM) and sulfaquinoxaline (SQ) in pork and chicken using solid-phase extraction (SPE) and high performance liquid chromatography (HPLC) ..
  65. ncbi [Qualification and quantification of 10 sulfonamides in animal feedstuff by high performance liquid chromatography-electrospray tandem mass spectrometry]
    Yan Qin
    Guangzhou Entry and Exit Inspection and Quarantine Bureau, Guangzhou 510623, China
    Se Pu 23:397-400. 2005
    ..sulfamethoxypyridazine (SMP), sulfamethoxazole (SMZ), sulfamonomethoxine (SMM), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX)...
  66. ncbi Determination of sulfonamide residues in the tissues of food animals using automated precolumn derivatization and liquid chromatography with fluorescence detection
    Craig D C Salisbury
    Canadian Food Inspection Agency, Centre for Veterinary Drug Residues, 116 Veterinary Rd, Saskatoon, SK, Canada
    J AOAC Int 87:1264-8. 2004
    ..of sulfachloropyridazine, sulfadiazine, sulfadimethoxine, sulfadoxine, sulfaethoxypyridazine, sulfamethazine, sulfaquinoxaline, and sulfathiazole residues in the muscle, liver, and kidney of food animals using sulfapyridine as internal ..
  67. ncbi Validation of a confirmatory method for the determination of sulphonamides in muscle according to the European Union regulation 2002/657/EC
    Ivan Pecorelli
    Istituto Zooprofilattico Sperimentale dell Umbria e delle Marche, Via Salvemini, Perugia 1 06126, Italy
    J Chromatogr A 1032:23-9. 2004
    ..sulfapyridine, sulfamerazine, sulfamethazine, sulfamonomethoxine, sulfachlorpyridazine, sulfamethoxazole, sulfaquinoxaline and sulfadimethoxine) in muscle samples...
  68. ncbi Determination of sulfonamide residues in eggs by liquid chromatography
    Naoto Furusawa
    Osaka City University, Faculty of Human Life Science, Osaka, Japan
    J AOAC Int 85:848-52. 2002
    ..antibacterials such as sulfamethazine (SMZ), sulfamonomethoxine (SMM), sulfadimethoxine (SDM), and sulfaquinoxaline (SQ) in eggs using liquid chromatography with a photodiode array detector...
  69. ncbi Comparison of ion-pairing and ion-suppressing liquid chromatographic methods for the determination of pyrimethamine and ormetoprim in chicken feed
    Shih Yuh Lin
    National Institute for Animal Health, Council of Agriculture, Tansui, Taipei, Taiwan
    J Chromatogr Sci 40:331-6. 2002
    ..Sulfamonomethoxine, sulfadimethoxine, sulfaquinoxaline, trimethoprim, amprolium, clopidol, and nicarbazin do not interfere with the detection of PYR or OMT...
  70. ncbi High-performance liquid chromatographic procedure for routine residue monitoring of seven sulfonamides in milk
    N Furusawa
    Faculty of Human Sciences, Osaka City University, Osaka, Japan
    Fresenius J Anal Chem 371:1031-3. 2001
    ..SMR), sulfadimidine (SDD), sulfamonomethoxine (SMM), sulfamethoxazole (SMX), sulfadimethoxine (SDM), and sulfaquinoxaline (SQ)) in milk using high-performance liquid chromatography (HPLC) with a photodiode array detector is ..
  71. ncbi Simultaneous determination of sulfaquinoxaline, sulfamethazine and pyrimethamine by liquid chromatography
    J J Berzas Nevado
    Departamento de Química Analítica y Tecnología de Alimentos, Facultad de Ciencias Quimicas, Universidad de Castilla La Mancha, Ciudad Real, Spain
    J Chromatogr A 870:169-77. 2000
    A liquid chromatography method is described to determine sulfaquinoxaline (SQX), sulfamethazine (SMT), and pyrimethamine (PMT), by using a Kromasil C18 column and a 40 mM NaH2PO4 buffer solution, containing 10 mM NaClO4 (pH 3...
  72. ncbi Quantitative determination of sulfonamide residues in foods of animal origin by high-performance liquid chromatography with fluorescence detection
    G Stoev
    Central Laboratory for Veterinary Control and Ecology, Sofia, Bulgaria
    J Chromatogr A 871:37-42. 2000
    ..The recovery for mix meat spiked with 1, 5 and 10 microg/kg of sulfonamides averaged 64%, 68% and 75%, respectively. Limits of quantitation were 1 microg/kg for sulfaquinoxaline and 0.5 microg/kg for the remaining sulfonamides.
  73. ncbi Determination of eight sulfonamides in bovine kidney by liquid chromatography/tandem mass spectrometry with on-line extraction and sample clean-up
    N Van Eeckhout
    Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium
    Rapid Commun Mass Spectrom 14:2331-8. 2000
    ..The method has been validated for sulfadimethoxine, sulfaquinoxaline, sulfamethazine, sulfamerazine, sulfathiazole, sulfamethoxazole, sulfadiazine and sulfapyridine...
  74. ncbi Application of ion-exchange cartridge clean-up in food analysis. V. Simultaneous determination of sulphonamide antibacterials in animal liver and kidney using high-performance liquid chromatography with ultraviolet and mass spectrometric detection
    Y Ito
    Aichi Prefectural Institute of Public Health, Nagoya, Japan
    J Chromatogr A 898:95-102. 2000
    ..sulfisozole, sulfamonomethoxine, sulfamethoxazole, sulfisoxazole, sulfadimethoxine, and sulfaquinoxaline) in animal liver and kidney was developed using a combination of clean-up on a Bond Elut PSA cartridge and ..
  75. ncbi Matrix solid-phase dispersion extraction and high-performance liquid chromatographic determination of residual sulfonamides in chicken
    K Kishida
    Graduate School of Human Life Science, Osaka City University, Japan
    J Chromatogr A 937:49-55. 2001
    ..sulfonamides (SAs) sulfadiazine, sulfadimidine, sulfamonomethoxine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline in chicken using matrix solid-phase dispersion (MSPD) with neutral aluminium oxide as an MSPD sorbent and ..
  76. ncbi Hypoprothrombinemia secondary to administration of sulfaquinoxaline to dogs in a kennel setting
    T M Neer
    Department of Clinical Sciences, College of Veterinary Medicine, Louisiana State University, Baton Rouge 70803
    J Am Vet Med Assoc 200:1344-5. 1992
    b>Sulfaquinoxaline, a coccidiostat readily available to the public, was mixed in the drinking water for this purpose by the owner. Secondary to its use, a bleeding disorder attributable to hypoprothrombinemia developed in several dogs...
  77. ncbi Determination of 14C residue in eggs of laying hens administered orally with [14C] sulfaquinoxaline
    B Shaikh
    FDA CVM Office of Research, 8401 Muirkirk Road, Laurel, MD 20708, USA
    Food Addit Contam 21:545-54. 2004
    Ten layer hens were dosed for 5 consecutive days with 6.2 mg kg(-1) [14C] sulfaquinoxaline (SQX). Eggs were collected from the hens during the 5-day dosing period and during a 10-day post-dose withdrawal period...
  78. ncbi Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells
    R F Branda
    Department of Medicine, University of Vermont, Burlington 05405
    Biochem Pharmacol 37:4557-64. 1988
    Chloroquinoxaline sulfonamide (CQS), a chlorinated derivative of sulfaquinoxaline (SQ), inhibited proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) were used...
  79. ncbi Stability of sulfonamide antibiotics in spiked pig liver tissue during frozen storage
    G K Thomas
    Australian Government Analytical Laboratories, Cottesloe, Western Australia
    J AOAC Int 80:988-95. 1997
    ..maximum residue limit) of each of sulfathiazole, sulfachlorpyridazine, sulfadimidine (sulfamethazine), sulfaquinoxaline, and sulfadimethoxine...
  80. ncbi Coccidiosis: a radiological study of sulphaquinoxaline distribution in infected and uninfected chickens
    R B Williams
    Wellcome Research Laboratories, Berkhamsted Hill, Berkhamsted, Hertfordshire, UK
    J Vet Pharmacol Ther 18:172-9. 1995
    ..tenella coincided with an overall 3.5-fold sustained increase of SQ concentration in chick tissues. An updated hypothesis including these new observations for the anticoccidial mode of action of SQ in chickens is expounded...
  81. ncbi Binding profile of spiramycin to oviducal proteins of laying hens
    N Furusawa
    Faculty of Human Life Science, Osaka City University, Osaka, 558 8585, Japan
    J Vet Med A Physiol Pathol Clin Med 47:585-91. 2000
    ..Of plasma, M-S9 and IS-S9, variation in SP concentration in the ranges from 1 to 20 micrograms/ml did not alter the binding properties of the drug...