latex

Summary

Summary: A milky, product excreted from the latex canals of a variety of plant species that contain cauotchouc. Latex is composed of 25-35% caoutchouc, 60-75% water, 2% protein, 2% resin, 1.5% sugar & 1% ash. RUBBER is made by the removal of water from latex.(From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) However, the term latex has been broadened in scope to include RUBBER and other synthetic polymers. Latexes are used as inert vehicles to carry antibodies or antigens in LATEX FIXATION TESTS.

Top Publications

  1. pmc Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex
    Keng See Chow
    Malaysian Rubber Board, Rubber Research Institute of Malaysia, Experiment Station, Selangor, Malaysia
    J Exp Bot 63:1863-71. 2012
  2. ncbi Plant latex and other exudates as plant defense systems: roles of various defense chemicals and proteins contained therein
    Kotaro Konno
    National Institute of Agrobiological Sciences, 1 2 Ohwashi, Tsukuba, Ibaraki 305 8634, Japan
    Phytochemistry 72:1510-30. 2011
  3. ncbi Structural and functional comparison of proteolytic enzymes from plant latex and snake venoms
    Júnia de O Costa
    Institute of Genetics and Biochemistry, Federal University of Uberlandia, MG, Brazil
    Biochimie 92:1760-5. 2010
  4. ncbi Procerain, a stable cysteine protease from the latex of Calotropis procera
    Vikash Kumar Dubey
    Molecular Biology Unit, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India
    Phytochemistry 62:1057-71. 2003
  5. ncbi Insights into rubber biosynthesis from transcriptome analysis of Hevea brasiliensis latex
    Keng See Chow
    Biotechnology Unit, Rubber Research Institute of Malaysia, Malaysian Rubber Board, RRIM Experiment Station, 47000 Sungai Buloh, Selangor, Malaysia
    J Exp Bot 58:2429-40. 2007
  6. ncbi Comparative toxicity of Euphorbia milii latex and synthetic molluscicides to Biomphalaria glabrata embryos
    Eduardo C Oliveira-Filho
    Laboratory of Environmental Toxicology, Department of Biological Sciences, National School of Public Health, FIOCRUZ, Rio de Janeiro, RJ 21040 361, Brazil
    Chemosphere 81:218-27. 2010
  7. pmc Involvement of HbPIP2;1 and HbTIP1;1 aquaporins in ethylene stimulation of latex yield through regulation of water exchanges between inner liber and latex cells in Hevea brasiliensis
    Kessarin Tungngoen
    Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Plant Physiol 151:843-56. 2009
  8. ncbi Ethylene stimulation of latex yield depends on the expression of a sucrose transporter (HbSUT1B) in rubber tree (Hevea brasiliensis)
    Anaïs Dusotoit-Coucaud
    Clermont Universite, Universite Blaise Pascal, UMRA 547 PIAF, F 63177 Aubiere, France
    Tree Physiol 30:1586-98. 2010
  9. pmc Induction of mucosal tolerance with recombinant Hev b 1 and recombinant Hev b 3 for prevention of latex allergy in BALB/c mice
    K Hufnagl
    Department of Pathophysiology, University of Vienna, Austria
    Clin Exp Immunol 133:170-6. 2003
  10. ncbi Papain protects papaya trees from herbivorous insects: role of cysteine proteases in latex
    Kotaro Konno
    National Institute of Agrobiological Sciences, 1 2 Ohwashi, Tsukuba, Ibaraki 305 8634, Japan
    Plant J 37:370-8. 2004

Detail Information

Publications287 found, 100 shown here

  1. pmc Metabolic routes affecting rubber biosynthesis in Hevea brasiliensis latex
    Keng See Chow
    Malaysian Rubber Board, Rubber Research Institute of Malaysia, Experiment Station, Selangor, Malaysia
    J Exp Bot 63:1863-71. 2012
    The cytosolic mevalonate (MVA) pathway in Hevea brasiliensis latex is the conventionally accepted pathway which provides isopentenyl diphosphate (IPP) for cis-polyisoprene (rubber) biosynthesis...
  2. ncbi Plant latex and other exudates as plant defense systems: roles of various defense chemicals and proteins contained therein
    Kotaro Konno
    National Institute of Agrobiological Sciences, 1 2 Ohwashi, Tsukuba, Ibaraki 305 8634, Japan
    Phytochemistry 72:1510-30. 2011
    Plant latex and other exudates are saps that are exuded from the points of plant damage caused either mechanically or by insect herbivory. Although many (ca...
  3. ncbi Structural and functional comparison of proteolytic enzymes from plant latex and snake venoms
    Júnia de O Costa
    Institute of Genetics and Biochemistry, Federal University of Uberlandia, MG, Brazil
    Biochimie 92:1760-5. 2010
    ..These toxins also display potential for clinical use in the treatment of hemostatic disorders...
  4. ncbi Procerain, a stable cysteine protease from the latex of Calotropis procera
    Vikash Kumar Dubey
    Molecular Biology Unit, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India
    Phytochemistry 62:1057-71. 2003
    A protease was purified to homogeneity from the latex of medicinal plant Calotropis procera (Family-Asclepiadaceae). The molecular mass and isoelectric point of the enzyme are 28.8 kDa and 9.32, respectively...
  5. ncbi Insights into rubber biosynthesis from transcriptome analysis of Hevea brasiliensis latex
    Keng See Chow
    Biotechnology Unit, Rubber Research Institute of Malaysia, Malaysian Rubber Board, RRIM Experiment Station, 47000 Sungai Buloh, Selangor, Malaysia
    J Exp Bot 58:2429-40. 2007
    ..In this study, 10,040 expressed sequence tags (ESTs) were generated from the latex of the rubber tree, which represents the cytoplasmic content of a single cell type, in order to analyse the latex ..
  6. ncbi Comparative toxicity of Euphorbia milii latex and synthetic molluscicides to Biomphalaria glabrata embryos
    Eduardo C Oliveira-Filho
    Laboratory of Environmental Toxicology, Department of Biological Sciences, National School of Public Health, FIOCRUZ, Rio de Janeiro, RJ 21040 361, Brazil
    Chemosphere 81:218-27. 2010
    ..This study was undertaken to compare the developmental toxicity of a plant molluscicide (Euphorbia milii latex, LAT) with that of three synthetic molluscicidal compounds...
  7. pmc Involvement of HbPIP2;1 and HbTIP1;1 aquaporins in ethylene stimulation of latex yield through regulation of water exchanges between inner liber and latex cells in Hevea brasiliensis
    Kessarin Tungngoen
    Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Plant Physiol 151:843-56. 2009
    ..Upon bark tapping, the laticifer cytoplasm (latex) is expelled due to liber tissue turgor pressure...
  8. ncbi Ethylene stimulation of latex yield depends on the expression of a sucrose transporter (HbSUT1B) in rubber tree (Hevea brasiliensis)
    Anaïs Dusotoit-Coucaud
    Clermont Universite, Universite Blaise Pascal, UMRA 547 PIAF, F 63177 Aubiere, France
    Tree Physiol 30:1586-98. 2010
    Hevea brasiliensis is an important industrial crop for natural rubber production. Latex biosynthesis occurs in the cytoplasm of highly specialized latex cells and requires sucrose as the unique precursor...
  9. pmc Induction of mucosal tolerance with recombinant Hev b 1 and recombinant Hev b 3 for prevention of latex allergy in BALB/c mice
    K Hufnagl
    Department of Pathophysiology, University of Vienna, Austria
    Clin Exp Immunol 133:170-6. 2003
    The prevalence of type I allergy to Hevea brasiliensis latex is particularly high among individuals with frequent exposure to latex products, such as health-care workers (HCW) and patients with spina bifida (SB)...
  10. ncbi Papain protects papaya trees from herbivorous insects: role of cysteine proteases in latex
    Kotaro Konno
    National Institute of Agrobiological Sciences, 1 2 Ohwashi, Tsukuba, Ibaraki 305 8634, Japan
    Plant J 37:370-8. 2004
    Many plants contain latex that exudes when leaves are damaged, and a number of proteins and enzymes have been found in it. The roles of those latex proteins and enzymes are as yet poorly understood...
  11. ncbi Got milk? The secret life of laticifers
    Jillian M Hagel
    Department of Biological Sciences, University of Calgary, Calgary, Alberta, T2N 1N4, Canada
    Trends Plant Sci 13:631-9. 2008
    ..The classification of laticifers is based on developmental patterns and overall morphology. The cytoplasmic latex exuded in response to damage often includes specialized metabolites, such as cardenolides, alkaloids and natural ..
  12. ncbi Hormonal treatment of the bark of rubber trees (Hevea brasiliensis) increases latex yield through latex dilution in relation with the differential expression of two aquaporin genes
    Kessarin Tungngoen
    Department of Biotechnology, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand
    J Plant Physiol 168:253-62. 2011
    ..Upon bark tapping, the latex is expelled due to liber turgor pressure...
  13. ncbi Funastrain c II: a cysteine endopeptidase purified from the latex of Funastrum clausum
    Susana R Morcelle
    Laboratorio de Investigacion de Proteinas Vegetales, Departamento de Ciencias Biologicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C C 711, B1900AVW, La Plata, Argentina
    Protein J 23:205-15. 2004
    A cysteine endopeptidase, named funastrain c II, was isolated and characterized from the latex of Funastrum clausum (Asclepiadaceae). The molecular mass (mass spectrometry) of the protease was 23.636 kDa...
  14. ncbi Latex allergy and associated risk factors in a group of Turkish patients with spina bifida
    Okan Gulbahar
    Department of Internal Medicine, Ege University Faculty of Medicine, Izmir, Turkey
    Turk J Pediatr 46:226-31. 2004
    Allergic reactions to latex are common in patients with spina bifida. Its incidence varies between 28% and 67%...
  15. pmc Ethylene stimulation of latex production in Hevea brasiliensis
    Jiahong Zhu
    Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Biosciences and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
    Plant Signal Behav 4:1072-4. 2009
    ..Ethylene, as a stimulant of latex production in H. brasiliensis, has been widely used in commercial latex production...
  16. ncbi Structural characterization of natural rubber based on recent evidence from selective enzymatic treatments
    Jitladda Tangpakdee Sakdapipanich
    Department of Chemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    J Biosci Bioeng 103:287-92. 2007
    ..The rubber particles of fresh latex were purified by washing, i.e...
  17. ncbi Anti-asthmatic potential of a D-galactose-binding lectin from Synadenium carinatum latex
    Alexandre P Rogerio
    Centro de Ciencias Biologicas, Campus Universitario Trindade, Universidade Federal de Santa Catarina, Florianopolis, SC 88049 900, Brazil
    Glycobiology 17:795-804. 2007
    Extracts from the plant Synadenium carinatum latex are widely and indiscriminately used in popular medicine to treat a great number of inflammatory disorders and although the mechanisms underlying these effects remain undefined, the ..
  18. ncbi Plant defense syndromes
    Anurag A Agrawal
    Department of Ecology and Evolutionary Biology and Department of Entomology, Cornell University, Ithaca, New York 14853, USA
    Ecology 87:S132-49. 2006
    ..seven defensive traits, no bivariate trade-offs, and notable positive correlations between trichome density and latex production, and between C:N ratio and leaf toughness...
  19. ncbi Philibertain g I, the most basic cysteine endopeptidase purified from the latex of Philibertia gilliesii Hook. et Arn. (Apocynaceae)
    C Sequeiros
    CENPAT CONICET Centro Nacional Patagónico, Blvd Brown s n, 9120, Puerto Madryn, Chubut, Argentina
    Protein J 24:445-53. 2005
    A new papain-like cysteine peptidase isolated from latex of Philibertia gilliesii Hook. et Arn., Apocynaceae (formerly Asclepiadaceae) has been purified and characterized...
  20. pmc Sucrose importation into laticifers of Hevea brasiliensis, in relation to ethylene stimulation of latex production
    Anaïs Dusotoit-Coucaud
    UMR 547 PIAF, INRA, Universite Blaise Pascal, 24 avenue des Landais, 63177 Aubiere Cedex, France
    Ann Bot 104:635-47. 2009
    The major economic product of Hevea brasiliensis is a rubber-containing cytoplasm (latex), which flows out of laticifers (latex cells) when the bark is tapped. The latex yield is stimulated by ethylene...
  21. ncbi Differential expression pattern of rubber elongation factor (REF) mRNA transcripts from high and low yielding clones of rubber tree (Hevea brasiliensis Muell. Arg.)
    P Priya
    Biotechnology Division, Rubber Research Institute of India, Kottayam 686009, India
    Plant Cell Rep 26:1833-8. 2007
    ..Since the immaturity period for Hevea is 6 years, identification of molecular marker for latex yield potential will be beneficial for early selection of high yielding clones...
  22. pmc Zinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosa
    M Carmen Conejo
    Department of Microbiology, School of Medicine, University of Seville, Seville, Spain
    Antimicrob Agents Chemother 47:2313-5. 2003
    The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD...
  23. ncbi Increased vascular permeability, angiogenesis and wound healing induced by the serum of natural latex of the rubber tree Hevea brasiliensis
    Ricardo José Mendonça
    Department of Biochemistry and Immunology, Ribeirao Preto School of Medicine, University of Sao Paulo, Ribeirao Preto SP, Brazil
    Phytother Res 24:764-8. 2010
    ..It has been suggested that the natural latex from Hevea brasiliensis showed wound healing properties and angiogenic activity...
  24. ncbi Characterization of proteins in latex of the opium poppy (Papaver somniferum) using two-dimensional gel electrophoresis and microsequencing
    G Decker
    Max Planck Institute for Biochemistry, Analytical Protein Chemistry Group, Martinsried, Germany
    Electrophoresis 21:3500-16. 2000
    The opium poppy (Papaver somniferum) belongs to the group of latex-containing plants. Latex is the milky-like fluid within laticifer cells...
  25. pmc Identification and characterization of genes associated with tapping panel dryness from Hevea brasiliensis latex using suppression subtractive hybridization
    Dejun Li
    Key Laboratory of Rubber Biology, Ministry of Agriculture, Rubber Research Institute, Chinese Academy of Tropical Agricultural Sciences, Danzhou, Hainan 571737, China
    BMC Plant Biol 10:140. 2010
    ..The present study is undertaken to generate information about the genes related to TPD in rubber tree...
  26. ncbi Identification of a putative triacylglycerol lipase from papaya latex by functional proteomics
    R Dhouib
    CNRS, Aix Marseille Universite, Enzymologie Interfaciale et Physiologie de la Lipolyse, France
    FEBS J 278:97-110. 2011
    b>Latex from Caricaceae has been known since 1925 to contain strong lipase activity. However, attempts to purify and identify the enzyme were not successful, mainly because of the lack of solubility of the enzyme...
  27. pmc Activation of the Epstein-Barr virus lytic cycle by the latex of the plant Euphorbia tirucalli
    A MacNeil
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Br J Cancer 88:1566-9. 2003
    ..The purpose of this study was to examine the effects of unpurified E. tirucalli latex on Epstein-Barr virus (EBV) gene expression...
  28. ncbi Proteins from latex of Calotropis procera prevent septic shock due to lethal infection by Salmonella enterica serovar Typhimurium
    José V Lima-Filho
    Departamento de Biologia, Universidade Federal Rural de Pernambuco, Campus Dois Irmãos, Recife, PE, Brazil
    J Ethnopharmacol 129:327-34. 2010
    The latex of Calotropis procera has been used in traditional medicine to treat different inflammatory diseases. The anti-inflammatory activity of latex proteins (LP) has been well documented using different inflammatory models...
  29. ncbi Biocompatibility of natural latex implanted into dental alveolus of rats
    Cláudia A C A Balabanian
    Department of Morphology, Stomatology and Physiology, School of Dentistry, University of Sao Paulo USP, Ribeirao Preto, Brazil
    J Oral Sci 48:201-5. 2006
    The present study investigated the biocompatibility of a biopolymer based on vegetable latex extracted from the Hevea brasiliensis rubber tree, implanted into the bony alveolar cavity after dental extraction in rats...
  30. ncbi An experimental investigation of the stability of ethylcellulose latex: correlation between zeta potential and sedimentation
    V Gallardo
    Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Granada, 18071 Granada, Spain
    Eur J Pharm Sci 26:170-5. 2005
    ..at explaining the experimental observations of the stability and redispersibility of an aqueous ethylcellulose latex through the electrokinetic characterization of the particles...
  31. ncbi Lipid transfer protein from Hevea brasiliensis (Hev b 12), a cross-reactive latex protein
    Donald H Beezhold
    Guthrie Research Institute, Sayre, Pennsylvania 18840, USA
    Ann Allergy Asthma Immunol 90:439-45. 2003
    b>Latex-allergic individuals experience clinical cross-reactivity to a large number of fruits and vegetables...
  32. ncbi Latex allergy: a model for therapy
    J M Rolland
    Department of Immunology, Monash University, Melbourne, Vic, Australia
    Clin Exp Allergy 38:898-912. 2008
    Allergy to natural rubber latex products emerged as an important clinical condition following an increase in the use of latex gloves for barrier protection in the early 1980s...
  33. pmc Latex-allergic patients sensitized to the major allergen hevein and hevein-like domains of class I chitinases show no increased frequency of latex-associated plant food allergy
    Christian Radauer
    Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Mol Immunol 48:600-9. 2011
    Allergies to certain fruits such as banana, avocado, chestnut and kiwi are described in 30-70% of latex-allergic patients...
  34. ncbi A silver-staining cDNA-AFLP protocol suitable for transcript profiling in the latex of Hevea brasiliensis (para rubber tree)
    Xiaohu Xiao
    Key Lab of Rubber Biology, Ministry of Agriculture, Danzhou, Hainan, 571737, China
    Mol Biotechnol 42:91-9. 2009
    ..Furthermore, the usage of radioactive isotope in typical protocols excludes their application in many labs. Latex, as the cytoplasm of rubber-producing cells sees a critical role in elucidating rubber biosynthesis and its ..
  35. pmc Polyphenoloxidase silencing affects latex coagulation in Taraxacum species
    Daniela Wahler
    Westphalian Wilhelms University of Munster, Institute of Biochemistry and Biotechnology of Plants, 48143 Muenster, Germany
    Plant Physiol 151:334-46. 2009
    b>Latex is the milky sap that is found in many different plants...
  36. ncbi The sucrose transporter HbSUT3 plays an active role in sucrose loading to laticifer and rubber productivity in exploited trees of Hevea brasiliensis (para rubber tree)
    Chaorong Tang
    Key Lab of Rubber Biology, Ministry of Agriculture and Rubber Research Institute, Chinese Academy of Tropical Agricultural Sciences, College of Agronomy, Hainan University, Danzhou, Hainan 571737, China
    Plant Cell Environ 33:1708-20. 2010
    ..other Hevea SUT genes, HbSUT3 was found to be the predominant member expressed in the rubber-containing cytoplasm (latex) of laticifers...
  37. ncbi Molecular identification and characterization of a gene associated with the onset of tapping panel dryness (TPD) syndrome in rubber tree (Hevea brasiliensis Muell.) by mRNA differential display
    Perumal Venkatachalam
    Plant Molecular Biology Lab, Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907, USA
    Mol Biotechnol 41:42-52. 2009
    ..tapping panel dryness (TPD) syndrome is considered as a complex physiological disorder which affects latex biosynthesis...
  38. ncbi Component-resolved diagnosis from latex allergy by microarray
    D G Ebo
    Department of Immunology Allergology Rheumatology, Faculty of Medicine, University of Antwerp, Antwerp, Belgium
    Clin Exp Allergy 40:348-58. 2010
    A positive specific IgE (sIgE) result for latex does not always mirror the clinical situation and is frequently found in individuals without overt latex allergy.
  39. ncbi Latex-free gloves: safer for whom?
    Ehab Aldlyami
    Department of Trauma and Orthopaedic, Northumbria Healthcare NHS Foundation Trust, England
    J Arthroplasty 25:27-30. 2010
    Increasing latex hypersensitivity among patients and health care workers has prompted the development of latex-free surgical gloves. Latex-free gloves must perform equally as the existing latex standard...
  40. doi Improving latex-allergy diagnosis: the clinical role of Hev b8-specific IgE
    L Antonicelli
    Allergy Unit, Department of Internal Medicine, Immuno Allergic and Respiratory Diseases, Ospedali Riuniti di Ancona, Ancona, Italy
    Allergy 63:620-1. 2008
  41. ncbi Significant role of bacterial undecaprenyl diphosphate (C55-UPP) for rubber synthesis by Hevea latex enzymes
    Atiya Rattanapittayaporn
    Department of Biochemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkla 90112, Thailand
    Macromol Biosci 4:1039-52. 2004
    Washed bottom fraction (BF) membrane-bound particles of centrifuged fresh Hevea latex were found to be very active in rubber biosynthesis (RB)...
  42. ncbi Integerrimides A and B, cyclic heptapeptides from the latex of Jatropha integerrima
    Wantana Mongkolvisut
    Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand
    J Nat Prod 69:1435-41. 2006
    Two new cyclic heptapeptides, integerrimides A and B, have been isolated from the latex of Jatropha integerrima. Their structures were elucidated by using extensive 1D and 2D NMR, MS, and chemical degradation...
  43. ncbi Laser diffraction: A new tool for identification and studies of physiological effectors involved in aggregation-coagulation of the rubber particles from Hevea latex
    Panida Kongsawadworakul
    Institut de Recherche pour le Developpement, 911 Avenue Agropolis, BP 64501, F 34394 Montpellier, France
    Plant Cell Physiol 44:707-17. 2003
    b>Latex coagulation is the main limiting factor of rubber yield in Hevea brasiliensis (rubber tree)...
  44. ncbi Osmotin purified from the latex of Calotropis procera: biochemical characterization, biological activity and role in plant defense
    Cléverson Diniz Teixeira de Freitas
    Departamento de Bioquímica e Biologia Molecular da, Universidade Federal do Ceara, Campus do Pici, CX, Postal 6033, Fortaleza, Ceara, CEP 60451 970, Brazil
    Plant Physiol Biochem 49:738-43. 2011
    A protein, similar to osmotin- and thaumatin-like proteins, was purified from Calotropis procera (Ait.) R.Br latex. The isolation procedure required two cation exchange chromatography steps on 50mM Na-acetate buffer (pH 5...
  45. ncbi Anti-inflammatory effect of the latex from Calotropis procera in three different experimental models: peritonitis, paw edema and hemorrhagic cystitis
    N M N Alencar
    Departamento de Farmacologia e Fisiologia, Universidade Federal do Ceara, Campus do Pici, Fortaleza Ceara, Brasil
    Planta Med 70:1144-9. 2004
    b>Latex from Calotropis procera is widely used in folk medicine as a rich source of biologically active compounds capable of promoting diverse benefits such as control of dermal fungal infections, antimicrobial activities and pain relief ..
  46. ncbi Permeability and reactivity of Thermotoga maritima in latex bimodal blend coatings at 80 degrees C: a model high temperature biocatalytic coating
    Olav K Lyngberg
    Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, USA
    Extremophiles 9:197-207. 2005
    ..Therefore a 55-microm thick, two layer (cell coat + polymer top coat) bimodal, adhesive latex coating of partially coalesced polystyrene particles was investigated at 80 degrees C using Thermotoga maritima as ..
  47. pmc Anticancer and cytotoxic properties of the latex of Calotropis procera in a transgenic mouse model of hepatocellular carcinoma
    Tenzin Choedon
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    World J Gastroenterol 12:2517-22. 2006
    To evaluate the anticancer property of the dried latex (DL) of Calotropis procera, a tropical medicinal plant, in the X15-myc transgenic mouse model of hepatocellular carcinoma and to elucidate its mechanism of action in cell culture.
  48. pmc Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity
    Sakihito Kitajima
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    BMC Biochem 11:6. 2010
    Plant latex is the cytoplasm of highly specialized cells known as laticifers, and is thought to have a critical role in defense against herbivorous insects...
  49. ncbi Larvicidal activity of latex and stem bark of Euphorbia tirucalli plant on the mosquito Culex quinquefasciatus
    Rajeshwari Yadav
    Natural Product Laboratory, Department of Zoology D D U Gorakhpur University, Gorakhpur
    J Commun Dis 34:264-9. 2002
    The methanolic, chloroform and ether extracts of Euphorbia tirucalli latex and stem bark were evaluated for larvicidal activity against laboratory-reared larvae of Culex quinquefasciatus (Diptera: Culicidae), vector of the brancroftian ..
  50. ncbi Establishment of new crops for the production of natural rubber
    Jan B van Beilen
    Département de Biologie Moléculaire Végétale, Biophore, Universite de Lausanne, CH 1015 Lausanne, Switzerland
    Trends Biotechnol 25:522-9. 2007
    ..This review summarizes our knowledge of plants that can serve as alternative sources of natural rubber, of rubber biosynthesis and the scientific gaps that must be filled to bring the alternative crops into production...
  51. ncbi Induction of tumor antigen-specific cytotoxic T cell responses in naïve mice by latex microspheres-based artificial antigen-presenting cell constructs
    Chuanlai Shen
    The Key Laboratory of Developmental Genes and Human Disease of Education Ministry, Genetics Research Center, Southeast University Medical School, 87 Dingjiaqiao Road, Nanjing, Jiangsu 210009, PR China
    Cell Immunol 247:28-35. 2007
    b>Latex microspheres-based artificial antigen-presenting cell constructs (aAPCs) are proved to be valuable tools to expand T cells ex vivo for adoptive cell therapy, but little is known about their potential for active immunization...
  52. ncbi The hevein domain of the major latex-glove allergen Hev b 6.01 contains dominant T cell reactive sites
    H D de Silva
    Co operative Research Centre for Asthma, Sydney, Australia
    Clin Exp Allergy 34:611-8. 2004
    Sensitization to natural rubber latex (Hevea brasiliensis) is a major cause of occupational asthma and rhinitis affecting frequent latex-glove users. Hev b 6.01, a known major latex allergen, is cleaved naturally into hevein (4...
  53. ncbi A mitogenic protein fraction in latex from Carica candamarcensis
    C A Silva
    Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, UFMG, Belo Horizonte, Brasil
    Planta Med 69:926-32. 2003
    b>Latex from Caricaceae contains a number of proteins believed to be part of a defense mechanism that protects these plants from wounding...
  54. ncbi Profile of latex sensitization and allergies in children and adolescents with myelomeningocele in São Paulo, Brazil
    A Bueno de Sã
    Division of Allergy and Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of Sao Paulo, Sao Paulo, Brazil
    J Investig Allergol Clin Immunol 23:43-9. 2013
    b>Latex allergy is an important cause of occupational allergy. In many countries the prevalence of latex allergy is still high and the profile of latex sensitization is unknown.
  55. ncbi Comparative evaluation of three Tactylon(TM) condoms and a latex condom during vaginal intercourse: breakage and slippage
    M Callahan
    Contraceptive Research and Development CONRAD Program, Eastern Virginia Medical School, Arlington, Virginia, USA
    Contraception 61:205-15. 2000
    ..and slippage rates of three male condom styles made of Tactylon(TM), a synthetic elastomer, to those of a marketed latex condom during vaginal intercourse. Safety and acceptability outcomes were also assessed...
  56. ncbi Inflammation induced by phytomodulatory proteins from the latex of Calotropis procera (Asclepiadaceae) protects against Salmonella infection in a murine model of typhoid fever
    Raquel S B Oliveira
    Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Campus do Pici, CX, Postal 6033, Fortaleza, Ceara, CEP 60451 970, Brazil
    Inflamm Res 61:689-98. 2012
    ..Typhimurium was investigated...
  57. ncbi Thrombin like activity of Asclepias curassavica L. latex: action of cysteine proteases
    H V Shivaprasad
    Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysore 570006, India
    J Ethnopharmacol 123:106-9. 2009
    To validate the scientific basis of plant latex to stop bleeding on fresh cuts. Cysteine protease(s) from Asclepias curassavica (Asclepiadaceae) plant latex was assessed for pro-coagulant and thrombin like activities.
  58. ncbi In vitro antimicrobial and antioxidant activities of anthrone and chromone from the latex of Aloe harlana Reynolds
    Gelila Asamenew
    Department of Pharmaceutical Chemistry and Pharmacognosy, School of Pharmacy, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    Phytother Res 25:1756-60. 2011
    In the search for new antimicrobial and antioxidant compounds from plants, the latex of the medicinal plant Aloe harlana Reynolds from Ethiopia was subjected to bioassay-guided fractionation, which led to the isolation of two known ..
  59. ncbi [Latex allergy. Diagnosis and therapeutic aspects]
    A Sanchez Palacios
    Unidad de Alergologia, Hospital Universitario Insular, Las Palmas de Gran Canaria, Spain
    Allergol Immunopathol (Madr) 29:212-21. 2001
    In the last two decades of the 20th century, latex allergy has reached epidemic proportions. Epidemiological studies demonstrate that 3-25 % of health personnel is allergic to latex...
  60. ncbi Purification and physicochemical characterization of a serine protease with fibrinolytic activity from latex of a medicinal herb Euphorbia hirta
    Girijesh Kumar Patel
    Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247 667, India
    Plant Physiol Biochem 52:104-11. 2012
    A 34 kDa serine protease, designated as hirtin, with fibrinolytic activity was purified to homogeneity from the latex of Euphorbia hirta by the combination of ion exchange and gel filtration chromatography...
  61. ncbi Colloid stable sorbents for cesium removal: preparation and application of latex particles functionalized with transition metals ferrocyanides
    Valentin Avramenko
    Institute of Chemistry, Far Eastern Branch, Russian Academy of Sciences, 159 ave 100 letiya Vladivostoka, Vladivostok 690022, Russia
    J Hazard Mater 186:1343-50. 2011
    ..using immobilization of transition metals (cobalt, nickel, and copper) ferrocyanides in nanosized carboxylic latex emulsions...
  62. ncbi Polyphenol oxidases from latex of Hevea brasiliensis: purification and characterization
    Dhirayos Wititsuwannakul
    Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Phytochemistry 61:115-21. 2002
    ..the B-serum obtained after repetitive freeze-thawing of the bottom fraction isolated from ultracentrifuged fresh latex. The B-serum was subjected to acetone precipitation and CM-Sepharose chromatography, affording two PPOs, PPO-I and ..
  63. ncbi Cytotoxicity of latex and non-latex orthodontic elastomeric ligatures on L929 mouse fibroblasts
    Rogério Lacerda dos Santos
    Departament of Orthodontics, Federal University of Rio de Janeiro, RJ, Brazil
    Braz Dent J 21:205-10. 2010
    This study investigated the cytotoxicity exists between latex and non-latex Orthodontic elastomeric ligatures...
  64. ncbi Wound healing activity of latex of Euphorbia caducifolia
    Manoj Goyal
    Lachoo Memorial College of Science and Technology, Pharmacy Wing, Jodhpur 342008, Rajasthan, India
    J Ethnopharmacol 144:786-90. 2012
    corrected] Euphorbia caducifolia is a Euphorbiaceae species native to Thar Desert of India, where latex of E. caducifolia (ECL) is used by the local inhabitants for treatment of bleeding wound, cutaneous eruption and other skin diseases...
  65. ncbi The effect of pH levels on nonlatex vs latex interarch elastics
    Paul S Sauget
    Department of Orthodontics and Oral Facial Genetics, Indiana University School of Dentistry, IUPUI, Indianapolis, 46202, USA
    Angle Orthod 81:1070-4. 2011
    To evaluate the force decay characteristics of nonlatex vs latex interarch elastics within the normal range of salivary pH levels.
  66. pmc Oral dosing with papaya latex is an effective anthelmintic treatment for sheep infected with Haemonchus contortus
    David J Buttle
    Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, S10 2RX, UK
    Parasit Vectors 4:36. 2011
    The cysteine proteinases in papaya latex have been shown to have potent anthelmintic properties in monogastric hosts such as rodents, pigs and humans, but this has not been demonstrated in ruminants.
  67. ncbi Use of a highly sensitive latex reagent with amino acid spacer for determination of C-reactive protein concentration in a variety of liver diseases
    Tomoe Komoriya
    College of Industrial Technology, Nihon University, 1 2 1 Izumi, Narashino, Chiba 275 8575, Japan
    J Biosci Bioeng 114:560-3. 2012
    ..In this report, we prepared a novel, ultra-sensitive latex-based CRP test using amino acid spacers with a high sensitivity and a wider assay range...
  68. pmc Resistance of Pseudomonas aeruginosa to imipenem induced by eluates from siliconized latex urinary catheters is related to outer membrane protein alterations
    L Martinez-Martinez
    Department of Microbiology, School of Medicine, University of Seville, Spain
    Antimicrob Agents Chemother 43:397-9. 1999
    ..against Pseudomonas aeruginosa HUS-3 decreased by 16 times in the presence of substances eluted from siliconized latex urinary catheters (SLUCs). SLUCs did not inactivate imipenem or increase beta-lactamase activity...
  69. ncbi Specific monoclonal antibodies and human immunoglobulin E show that Hev b 5 is an abundant allergen in high protein powdered latex gloves
    M F Sutherland
    Department of Allergy, Asthma and Clinical Immunology, The Alfred Hospital and Monash University, Victoria, Australia
    Clin Exp Allergy 32:583-9. 2002
    Hev b 5 is a major latex allergen recognized predominantly by latex-allergic health care workers (HCWs)...
  70. ncbi The influence of pH levels on mechanical and biological properties of nonlatex and latex elastics
    Rogério Lacerda Dos Santos
    Department of Orthodontics, Federal University of Campina Grande, Paraiba, Brazil
    Angle Orthod 82:709-14. 2012
    ..To evaluate the influence of pH levels on interarch elastics with regard to force decay and cytotoxicity...
  71. ncbi Visualizing a plant defense and insect counterploy: alkaloid distribution in Lobelia leaves trenched by a plusiine caterpillar
    Craig B Oppel
    Department of Biology, University of Central Arkansas, Conway, Arkansas 72035, USA
    J Chem Ecol 35:625-34. 2009
    Insects that feed on plants protected by latex canals often sever leaf veins or cut trenches across leaves before feeding distal to the cuts...
  72. ncbi Two new cytotoxic cardenolides from the latex of Antiaris toxicaria
    Hao Fu Dai
    Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China
    J Asian Nat Prod Res 11:832-7. 2009
    Two new cardenolides, toxicarioside F (1) and toxicarioside G (2), were isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Their structures were elucidated on the basis of spectral data and chemical evidence...
  73. ncbi Anti-diarrhoeal activity of the latex of Calotropis procera
    S Kumar
    Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, 110 029, New Delhi, India
    J Ethnopharmacol 76:115-8. 2001
    The dry latex (DL) of Calotropis procera (Asclepiadaceae), a potent anti-inflammatory agent has been evaluated for anti-diarrhoeal activity...
  74. ncbi Purification and characterization of a wound-inducible thaumatin-like protein from the latex of Carica papaya
    Yvan Looze
    Laboratoire de Chimie Générale CP 206 4, Institut de Pharmacie, Universite Libre de Bruxelles, Campus de la Plaine, Boulevard du Triomphe, 1050 Brussels, Belgium
    Phytochemistry 70:970-8. 2009
    A 22.137 kDa protein constituent of fresh latex was isolated both from the latex of regularly damaged papaya trees and from a commercially available papain preparation...
  75. ncbi Latex use as an occlusive membrane for guided bone regeneration
    Cibele Ereno
    Programa de Pós Graduação em Biologia Oral, Universidade do Sagrado Coração, PRPPG, Bauru, Sao Paulo, Brazil
    J Biomed Mater Res A 95:932-9. 2010
    b>Latex extracted from Hevea brasiliensis was used as an occlusive membrane for guided bone regeneration. Twenty-four rabbits were divided in two groups: treated and control group...
  76. ncbi Role of lipid rafts in innate immunity and phagocytosis of polystyrene latex microspheres
    Goshi Nagao
    Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278 8510, Japan
    Colloids Surf B Biointerfaces 84:317-24. 2011
    ..Macrophage phagocytosis of polystyrene latex microspheres was examined and assayed by treatment of macrophages with the cholesterol depletor methyl-β-..
  77. ncbi Latex constituents from Calotropis procera (R. Br.) display toxicity upon egg hatching and larvae of Aedes aegypti (Linn.)
    Márcio Viana Ramos
    Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, Campus do Pici, 60451 970 Fortaleza, CE, Brasil
    Mem Inst Oswaldo Cruz 101:503-10. 2006
    ..This work deals with the fractionation of the crude latex produced by the green parts of the plant and aims to evaluate its toxic effects upon egg hatching and larval ..
  78. pmc Development of a rapid dipstick with latex immunochromatographic assay (DLIA) for diagnosis of schistosomiasis japonica
    Li Ling Yu
    Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, Hangzhou, 310013, China
    Parasit Vectors 4:157. 2011
    ..In this study, we developed a novel rapid dipstick with latex immunochromatographic assay (DLIA) to detect anti-Schisaosoma japonicum antibodies in human serum.
  79. ncbi Uptake, excretion and toxicity of nano-sized latex particles on medaka (Oryzias latipes) embryos and larvae
    Masahiko Manabe
    Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Aquat Toxicol 105:576-81. 2011
    ..In this study, we investigated the effect of nano-sized, fluorescent, latex particles on the freshwater fish, medaka (Oryzias latipes)...
  80. ncbi Purification and biochemical characterization of asclepain c I from the latex of Asclepias curassavica L
    Constanza Liggieri
    Laboratorio de Investigacion de Proteinas Vegetales, Departamento de Ciencias Biologicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C C 711, B1900AVW, La Plata, Argentina
    Protein J 23:403-11. 2004
    In this work we report the isolation, purification and characterization of a new protease from latex of Asclepias curassavica L. Crude extract (CE) was obtained by gathering latex on 0...
  81. ncbi Lupeol, a triterpenoid isolated from Calotropis gigantea latex ameliorates the primary and secondary complications of FCA induced adjuvant disease in experimental rats
    Venkatesan Saratha
    Department of Biochemistry, University of Madras, Guindy Campus, Chennai 600025, Tamilnadu, India
    Inflammopharmacology 20:27-37. 2012
    ..Calotropis gigantea is a xerophytic, latex producing medicinal plant widely distributed in nature...
  82. ncbi Study of blood contact in simulated surgical needlestick injuries with single or double latex gloving
    Andreas Wittmann
    Department of Safety Engineering, University of Wuppertal, and the Helios Klinikum Wuppertal, Klinik für Nuklearmedizin, Wuppertal, Germany
    Infect Control Hosp Epidemiol 30:53-6. 2009
    ..The aim of this study was to measure the quantity of blood transferred at the point of a percutaneous injury by using radioactively labeled blood...
  83. ncbi Perioperative latex allergy
    R Bernardini
    San Giuseppe Hospital, Empoli, Florence, Italy
    Int J Immunopathol Pharmacol 24:S55-60. 2011
    The prevalence of latex allergy varies greatly depending on the population studied and the methods used to detect sensitization...
  84. ncbi Detection of three wound-induced proteins in papaya latex
    Mohamed Azarkan
    Laboratoire de Chimie Générale I, Faculty of Medicine, University of Brussels, Campus Erasme CP 609, 808 Route de Lennik, B 1070 Brussels, Belgium
    Phytochemistry 65:525-34. 2004
    The effects of routine mechanical wounding for latex collection from unripe fruits of the tropical Carica papaya tree were investigated. For that purpose, the protein composition of three different latexes was analyzed...
  85. ncbi Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-γ-mediated airway hyperreactivity in a murine model of natural rubber latex allergy
    Rita Haapakoski
    Unit of Excellence for Immunotoxicology, Finnish Institute of Occupational Health, Helsinki, Finland
    Am J Respir Cell Mol Biol 44:639-47. 2011
    ..Using natural rubber latex (NRL)-induced murine model of asthma, we demonstrated that intradermal CpG administration with allergen reduced ..
  86. ncbi Liquid marbles prepared from pH-responsive sterically stabilized latex particles
    Syuji Fujii
    Department of Applied Chemistry, Faculty of Engineering, Osaka Institute of Technology, 5 16 1 Ohmiya, Osaka 535 8585, Japan
    Langmuir 27:8067-74. 2011
    Submicrometer-sized pH-responsive sterically stabilized polystyrene (PS) latex particles were synthesized by dispersion polymerization in isopropyl alcohol with a poly[2-(diethylamino)ethyl methacrylate]- (PDEA-) based macroinitiator...
  87. pmc Laticifer-specific cis-prenyltransferase silencing affects the rubber, triterpene, and inulin content of Taraxacum brevicorniculatum
    Janina Post
    Westphalian Wilhelms University of Munster, Institute of Plant Biology and Biotechnology, 48143 Münster, Germany
    Plant Physiol 158:1406-17. 2012
    ..Taraxacum koksaghyz and Taraxacum brevicorniculatum, produce large amounts of high-quality natural rubber in their latex, the milky cytoplasm of specialized cells known as laticifers...
  88. ncbi Management of occupational allergy to natural rubber latex in a medical center: the importance of quantitative latex allergen measurement and objective follow-up
    Loren W Hunt
    Allergic Diseases Research Laboratory and the Departments of Pediatrics and Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Allergy Clin Immunol 110:S96-106. 2002
    ..or undetectable allergen content greatly reduced the concentration of allergen in the work site, reduced the number of new cases of occupational allergy to rubber, and allowed individuals with latex allergy to work at their usual jobs.
  89. ncbi Isolation and characterization of the early nodule-specific protein homologue (Hev b 13), an allergenic lipolytic esterase from Hevea brasiliensis latex
    Siti Arija M Arif
    Rubber Research Institute of Malaysia, 50450 Kuala Lumpur, Malaysia
    J Biol Chem 279:23933-41. 2004
    Recurring reports of a highly allergenic 42-46-kDa protein in Hevea brasiliensis latex appeared to have been resolved with the discovery of a 43-kDa allergenic latex protein that was a homologue to patatin...
  90. ncbi Rabbit retinal neovascularization induced by latex angiogenic-derived fraction: an experimental model
    R B Sampaio
    Department of Ophthalmology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
    Curr Eye Res 35:56-62. 2010
    To create a retinal neovascularization experimental model using intravitreal injection of microspheres loaded with latex-derived angiogenic fraction.
  91. ncbi Osmotin from Calotropis procera latex: new insights into structure and antifungal properties
    Cléverson Diniz Teixeira de Freitas
    Departamento de Biologia, Universidade Federal do Piaui, Bairro Melladão, Floriano Piauí, Brazil
    Biochim Biophys Acta 1808:2501-7. 2011
    ..structural properties and mechanisms of the antifungal action of CpOsm, a purified osmotin from Calotropis procera latex. Fluorescence and CD assays revealed that the CpOsm structure is highly stable, regardless of pH levels...
  92. ncbi Effect of the Synadenium carinatum latex lectin (ScLL) on Leishmania (Leishmania) amazonensis infection in murine macrophages
    Sandra R Afonso-Cardoso
    Instituto de Ciencias Biomedicas, Universidade Federal de Uberlandia, Avenida Pará 1720, Uberlandia, MG, Brazil
    Exp Parasitol 128:61-7. 2011
    Antiparasitic effect of a lectin isolated from Synadenium carinatum latex (ScLL) was evaluated against Leishmania (Leishmania) amazonensis promastigotes/amastigotes...
  93. ncbi Proteomic analysis of latex from the rubber-producing plant Taraxacum brevicorniculatum
    Daniela Wahler
    Molecular Biotechnology, RWTH Aachen, Aachen, Germany
    Proteomics 12:901-5. 2012
    Many plants produce latex, a specialized, metabolically active cytoplasm. This is generally regarded as a defensive trait but latex may also possess additional functions...
  94. ncbi Measurement of airborne latex allergens
    Xaver Baur
    Institute of Occupational Medicine Hamburg, University of Hamburg, Adolph Schoenfelder Strasse 5, D 22083, Hamburg, Germany
    Methods 27:59-62. 2002
    ..Several studies demonstrate that the use of powdered allergenic latex gloves leads to a significant aeroallergen load which is responsible for IgE-mediated rhinitis, bronchial asthma, ..
  95. ncbi Puncture resistance and stiffness of nitrile and latex dental examination gloves
    H B Patel
    School of Dentistry, University of Birmingham, St Chad s Queensway, Birmingham B4 6NN
    Br Dent J 196:695-700; discussion 685; quiz 707. 2004
    The aim of the current study was to assess the puncture resistance and stiffness of nitrile and latex dental examination gloves.
  96. ncbi Sub-femtomolar electrochemical detection of DNA hybridization based on latex/gold nanoparticle-assisted signal amplification
    Suttiporn Pinijsuwan
    School of Bioresources and Technology, King Mongkut s University of Technology Thonburi, Bangkhuntien, Bangkok 10150, Thailand
    Anal Chem 80:6779-84. 2008
    We report a relatively simple electrostatic method for modifying submicrometer-size latex spheres with gold nanoparticles (AuNPs) based on layer-by-layer modification of the latex by polyelectrolytes...
  97. pmc Time and force dependence of the rupture of glycoprotein IIb-IIIa-fibrinogen bonds between latex spheres
    H L Goldsmith
    McGill University Medical Clinic, Montreal General Hospital Research Institute, Montreal, Quebec, Canada
    Biophys J 78:1195-206. 2000
    We studied the shear-induced breakup of doublets of aldehyde/sulfate (A/S) latex spheres covalently linked with purified platelet GPIIb-IIIa receptor, and cross-linked by fibrinogen...
  98. pmc Calotropis procera latex extract affords protection against inflammation and oxidative stress in Freund's complete adjuvant-induced monoarthritis in rats
    Vijay L Kumar
    Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Mediators Inflamm 2007:47523. 2007
    In view of the well-established anti-inflammatory properties of latex of Calotropis procera (DL), the present study was carried out to evaluate the protective effect of its methanol extract (MeDL) against inflammation and oxidative ..
  99. ncbi Biosynthesis of silver nanoparticles using latex from few Euphorbian plants and their antimicrobial potential
    Satish V Patil
    School of Life Sciences, North Maharashtra University, Jalgaon, India
    Appl Biochem Biotechnol 167:776-90. 2012
    ..This study is the first report of one-step solvent-free synthesis of AgNPs using Euphorbiaceae plant latex. Among evaluated eight latex-producing plants, four (Jatropha curcas, Jatropha gossypifolia, Pedilanthus ..
  100. ncbi Diagnostic value of specific IgE analysis in latex allergy
    Mehmet Unsel
    Division of Allergy, Department of Internal Medicine, Tepecik Training and Research Hospital, Izmir, Turkey
    Int Arch Allergy Immunol 158:281-7. 2012
    The precision of the methods used to diagnose latex allergy is of great importance due to false-positive results. Neither the skin prick test (SPT) nor the latex-specific IgE assay has 100% diagnostic accuracy...
  101. ncbi A molecular and in silico characterization of Hev b 4, a glycosylated latex allergen
    Adeel Malik
    Department of Biosciences, Jamia Millia Islamia, New Delhi 110025, India
    Int J Biol Macromol 42:185-90. 2008
    Hev b 4 is a heavily glycosylated latex allergen with seven attached N-glycans, comprising of both oligomannose and complex type structures...

Research Grants63

  1. ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION (ADME) IN MAMMALS
    Jacob McDonald; Fiscal Year: 2013
    ..consumed by the tire industry, but is also present in other products such as belts, cables, hoses, rubber gloves, latex gloves, printing screen rollers, and athletic shoes...
  2. The Roles of Conserved outer-membrane proteins in SFG rickettsia pathogenesis
    Juan J Martinez; Fiscal Year: 2013
    ..coli, purified proteins and protein coupled latex beads...
  3. The CryptoART Study: Decreasing mortality associated with initiation of antiretro
    CHIRATIDZO ELLEN NDHLOVU; Fiscal Year: 2013
    ..We will test the performance of the LFA against gold standards (cryptococcal antigen latex agglutination assays, blood and CSF cultures) and determine its sensitivity and specificity in whole blood (finger ..
  4. Nanoscale Optical Fiber Biosensor Assays for Detection of Category A and B Select
    Thomas J Inzana; Fiscal Year: 2010
    ..In addition, we will use Real-Time PCR and latex agglutination assays as control assays to compare the sensitivity and specificity of DNA-based or antigen- based ..
  5. Microthrombus Formation Triggers Lung Injury in Sepsis
    BRUCE ALLAN HARMS; Fiscal Year: 2012
    ..sepsis development, we will correlate microthrombus location with trapping patterns of small-diameter fluorescent latex particles infused into lung capillaries to determine the association between microthrombus formation and alveolar ..
  6. Antibacterial, antifungal, antiviral, and antispore paints
    YUYU contact SUN; Fiscal Year: 2011
    ..tetramethyl-4-piperidinyl acrylate (Cl-TMPA), will be polymerized to produce polymeric N-halamine latex emulsions...
  7. Behavioral and Manufacturing Science to Commercially Develop Fitted Condoms
    PATRICK SEAN SULLIVAN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): A policy statement by the World Health Organization notes that, "the male latex condom is the single, most efficient, available technology to reduce the transmission of HIV and other sexually ..
  8. Nanoparticle-Hydrogel Strips for Detection of Staphylococcal Enterotoxins
    Chuanmin Ruan; Fiscal Year: 2009
    ..Current SEB detection is enzyme-linked immunosorbent assay (ELISA), reverse phase latex agglutination and reverse transcription polymerase chain reaction (RT-PCR)...
  9. Beclin Deficiency and Microglial Impairment in Alzheimer's Disease
    Tony Wyss-Coray; Fiscal Year: 2013
    ..in microglia impairs their capacity to clear amyloid plaques from brain sections in situ as well as to phagocytose latex beads in culture...
  10. Evaluation of a progesterone vaginal ring as a new contraceptive option in India
    REGINE SITRUK WARE; Fiscal Year: 2013
    ..4) To optimize the technology of progesterone rings and prepare a transfer of technology to Hindustan Latex in India...
  11. ESCHERICHIA COLI LT-RELATED ENTEROTOXINS
    RICHARD FINKELSTEIN; Fiscal Year: 1991
    ..The technology to be used: involves; a) immunologic assays (enzyme-linked immunosorption assays (ELISA), latex particle agglutination tests (LPAT), immuno-blotting precipitin and neutralization tests) using polyclonal and ..
  12. Bacterial Interactions with Corneal Epithelium in Health and Disease
    SUZANNE MARIANE JANETE FLEISZIG; Fiscal Year: 2013
    ..Outcomes to be quantified include bacterial traversal, antimicrobial activity, mRNA and protein expression, and colocalization of proteins, bacteria and latex beads of various sizes.
  13. Direct visualization of the FG nups, the selective gating for nuclear transport
    Loren E Hough; Fiscal Year: 2010
    ..We have covalently attached the FG repeat portion of two archetypal FG nups to 40 nm radius latex beads in an orientation and density comparable to that found in the NPC...
  14. COATING OF URINARY PROTHESES TO PREVENT ENCRUSTATION
    Harmeet Sidhu; Fiscal Year: 2000
    ..we propose to evaluate the three known oxalate-degrading enzyme systems for a) efficacy in coating silicon- latex biomaterial surfaces, b) stability of enzymatic activity following coating plus its survival in a urinary ..
  15. Keratinocyte Costimulation and Th2-Cell Immune Deviation
    Anthony Gaspari; Fiscal Year: 2009
    ..is highly relevant to the understanding of development of type I allergic responses to haptens, natural rubber latex (NRL)-containing medical devices, and atopic diseases in general...
  16. RAI CONDOM: Feasibility & Acceptability Study, Phase 1 Pilot Clinical Research
    DANIEL RESNIC; Fiscal Year: 2010
    ..made of a biocompatible, viral-impermeable silicone, which may provide better sensation and less breakage than latex products and provide maximum protection against viral transmission...
  17. Novel Topical Treatment of Eczema
    Bakul Bhatt; Fiscal Year: 2006
    ..on the skin and deter hand washing, and also provide a route for skin sensitization to natural rubber latex proteins...
  18. NOVEL ACCESSORY FOR URINARY LEG BAGS
    SHANTHA SARANGAPANI; Fiscal Year: 1999
    ..b>latex tubing used currently)...
  19. ACCEPTABILITY AND SAFETY STUDY OF JANESWAY FEMALE CONDOM
    Ron Frezieres; Fiscal Year: 2000
    ..The new design attaches a disposable latex condom to the midsection of specially designed cotton underwear...
  20. A new hemagglutination method for detection of unexpected antibodies
    SIMON BYSTRYAK; Fiscal Year: 2012
    ..a general approach for enhancement and detection of agglutination of particles of different origin, including latex, silica microparticles, and biological cells...
  21. ANATOMY OF IDENTIFIED CELL POPULATIONS IN VISUAL CORTEX
    BARBARA MC GUIRE; Fiscal Year: 1991
    ..Meynert cells and layer 4B cells will be identified in living brain slices by retrograde transport of fluorescent latex microspheres from areas MT, V2 and the superior colliculus...
  22. Rapid Test for Monitoring Dust Mite Avoidance in Homes
    Martin Chapman; Fiscal Year: 2004
    ..Lateral flow technology will enable tests for food and latex allergens to be developed, as well as a new generation of rapid allergen diagnostic tests using genetically ..
  23. NON-ALLERGENIC SURGICAL GLOVES AND CONDOMS
    JOHN GARDON; Fiscal Year: 2000
    Surgical gloves and condoms are currently made from vulcanized natural rubber (VNR) latex. Its protein content causes severe Type I allergies in sensitized individuals, involving major occupational and medical hazards...
  24. IMMUNOPROBES FOR LUBRICIN FROM HUMAN SYNOVIAL FLUID
    Gregory Jay; Fiscal Year: 2003
    ..An arthrotripsometer composed of latex oscillating against glass employed by the PI reproduced critical findings of previous studies using cartilage ..
  25. ENGINEERING INTEGRIN--MEDIATED CELL MIGRATION
    Douglas Lauffenburger; Fiscal Year: 2002
    ..An optical trap assay that employs integrin antibodies (anti-aIIbb3 or anti-a5) chemically conjugated to latex beads will be used to measure the front-vs-rear asymmetry in integrin/cytoskeleton linkage in CHO cells with ..
  26. REACTION MECHANISMS FOR ENZYMES
    JULES SHAFER; Fiscal Year: 1990
    Papain, a thiol protease from papaya latex, will be studied to determine the role of Asp-158 in catalysis and to determine the effect of Asp-158 on the interactive ionization of His-159 and Cys-25 at the active site of papain...
  27. MOLECULAR BIOLOGY OF INFECTION WITH M TUBERCULOSIS
    Lee Riley; Fiscal Year: 2002
    ..tuberculosis that promoted uptake of latex microspheres coated with the protein into nonphagocytic cells...
  28. SYNAPTIC INTEGRATION AND LESIONING OF PRE-LABELED GRAFTS
    Dennis Turner; Fiscal Year: 1993
    ..this the grafted neurons will be pre-labeled with a laser sensitive photo-activated dye, chlorin e6 attached to latex microspheres...
  29. A validated asthma questionnaire for healthcare workers
    George Delclos; Fiscal Year: 2003
    ..exposures risk factors (RAST IgE-specific antibody panel against common environmental aeroallergens and latex)...
  30. TREATMENT OF ARDS WITH FRUCTOSE DIPHOSPHATE
    ANGEL MARKOV; Fiscal Year: 1991
    ..3) The "respiratory burst" by human or dog neutrophils stimulated with latex particles or PMA or bacteria is inhibited by addition of FDP...
  31. WOUND HEALING ACCELERATION USING NATURAL PRODUCTS
    Gerald Hammond; Fiscal Year: 1999
    ..Characterization of the active principle from Anredera diffusa and bioassay-guided fractionation of Jatropa curcas latex. The former was isolated during the previous grant period. 2...
  32. TRANSLOCATING BACTERIA: ROLE IN POSTSURGICAL SEPSIS
    Carol Wells; Fiscal Year: 1990
    ..Inert particles such as ferritin, starch, and latex beads also translocate...
  33. TURNOVER OF SUBSTANCES IN THE OUTFLOW PATHWAY OF THE EYE
    Arnold Miller; Fiscal Year: 1990
    ..by these cells of various radiolabeled particles including lens material, red blood cells and protein-laden latex spheres will be determined...
  34. ISOLATION OF TOXINS FROM C. DIFFICILE & C. SORDELLII
    Tracy Wilkins; Fiscal Year: 1992
    ..intestinal enzymes so we may be able to treat the disease by giving large amounts of the receptor attached to latex beads...
  35. PHOTOCHEMICAL TARGETING OF TRABECULAR MESHWORK CELLS
    Mark Latina; Fiscal Year: 1991
    ..Selectively will be achieved by coupling a photosensitizer to a carrier (latex microspheres) which will be preferentially phagocytosed by TM cells...
  36. COLLABORATIVE STUDY OF 1,3 BUTADIENE BIOMARKERS
    Thomas Smith; Fiscal Year: 2002
    ..Eighty (80) subjects will be drawn from male Taiwanese petrochemical workers producing butadiene latex and related products at 10 large plants (250 workers total)...
  37. New Condom: Feasibility Study
    DANIEL RESNIC; Fiscal Year: 2006
    ..a new condom made from silicone, a material that may offer better sensation and be less prone to breakage than latex or plastic...
  38. Alcohol, Gender, Power, and Condom use among Adults in Northern Tanzania
    SARAH WOOLF; Fiscal Year: 2009
    ..route of transmission among this population, one way to prevent the spread of HIV is through the use of a male latex condom...
  39. ELEMENTS IN THE TRABECULAR MESHWORK
    Thomas Richardson; Fiscal Year: 1991
    ..trabecular cells - both receptor mediated mechanisms (Fc, C3 and zymosan receptors) and non-specific mechanisms (latex particles) will be studied; and (4) characterize the distribution of specific cytoskeletal proteins in trabecular ..
  40. A new hemagglutination method for blood grouping
    SIMON BYSTRYAK; Fiscal Year: 2013
    ..Significantly, the method presents a general approach for enhancement and detection of agglutination of particles of different origin, including latex, silica microparticles, and biologial cells.
  41. CELL SURFACE ARCHITECTURE OF EMBRYOS AND SPERM
    MARTHA SPIEGELMAN; Fiscal Year: 1980
    ..Using anti-tw18 serum and antibody coated latex spheres, a proportion of primitive streak embryos from segregating litters show labeling in the scanning electron ..
  42. Aging, Angiogenesis, and the Neuropeptide Y (NPY) System
    Joanna Kitlinska; Fiscal Year: 2002
    ..New vessels will be detected by CD31 immunostaining and by their casting by perfusion with latex. Systemic and local NPY levels, as well as expression of angiogenic stimuli, will be determined...
  43. DETERMINANTS OF CONDOM USE TO PREVENT AIDS
    Daniel Montano; Fiscal Year: 1992
    ..There is evidence that condoms, particularly latex, prevent the transmission of HIV if they are used correctly and consistently...
  44. PREVENTION OF ALLERGIC RESPONSE TO LATEX RUBBER
    MELVIN KEYES; Fiscal Year: 1993
    Recently latex allergic hypersensitivity has emerged as a new and unexpected health care problem. Latex rubber is used in many products where tissue contact is possible for both the health care practitioner and the patient...
  45. ISOLATION AND CHARACTERIZATION OF PEYER'S PATCH M CELLS
    Jacques Pappo; Fiscal Year: 1993
    ..will enable the positive identification of isolated M cells, and of M cells after phagocytosis of fluoresceinated latex microspheres...
  46. OXYGEN AND OXY-RADICALS IN PHAGOCYTIC KILLING
    Michael Thomas; Fiscal Year: 1990
    ..Chemical probes, introduced in small quantities coated onto latex beads, will be used to test for various oxidants that are formed in the phagosome...
  47. HYPOXIC RESPONSES OF MEDULLARY CARDIORESPIRATORY NEURONS
    Judith Neubauer; Fiscal Year: 2001
    ..this application will investigate the mechanisms underlying these responses in retrogradely labeled (fluorescent latex beads) premotor VRG (hypoxia- depressed) and RVLM (hypoxia-excited) neurons dissociated and cultured from neonatal ..
  48. ALLERGY, IMMUNOLOGY, AND ANESTHETIC ACTION
    GIRISH MOUDGIL; Fiscal Year: 2000
    ..will discuss the pathogenesis and diagnosis of perioperative allergic drug reactions, newer insights into latex allergy, anaphlactoid reactions and volume expanders, and anesthesia in patients at risk of hypersensitivity ..
  49. SURFACE MODIFYING TO IMPROVE URINARY CATHETER FUNCTION
    DAVID CLAPPER; Fiscal Year: 1990
    ..The two most commonly used types of urinary catheters (latex and silicone) will be coated with reagents that have improved wettability and reduced bacteria colonization when ..
  50. FLOW-INDUCED NEAR-WALL EXCESS OF PLATELETS
    Eugene Eckstein; Fiscal Year: 1993
    ..method, developed and demonstrated in the last two years, captures the distribution of fluorescent platelet-sized latex beads in a blood suspension flowing through a polyethylene tube by rapidly freezing it with liquid nitrogen...
  51. PLATELETS IN RHEUMATIC DISEASE
    Mark Ginsberg; Fiscal Year: 2000
    ..monoclonal antibodies which preferentially recognize occupied forms of B3 integrins, 2) binding of fluorescent latex beads bearing bound adhesive proteins, and 3) quantitative binding of ligands to purified integrins in vitro...
  52. Validation of topography-biased antibody libraries
    Sylvia Smith; Fiscal Year: 2005
    ..For instance, the libraries will be screened with the allergen for latex (Hevea brasilian), the toxin of one of the most lethal scorpions known (Centruroides noxius) and the biological ..
  53. Thick tissue imaging with auto-confocal microscopy
    Jerome Mertz; Fiscal Year: 2004
    ..using simple samples such as latex beads (or cultured cells) in agarose (or collagen) gels...
  54. IMMUNOTHERAPY FOR LATEX RUBBER ALLERGY
    N Adkinson; Fiscal Year: 2007
    Allergic sensitivity to natural rubber latex has become a major occupational hazard of healthcare workers and some patients with frequent latex rubber exposures. Between 2.2 and 10...
  55. CELL BIOLOGY OF RETINAL PIGMENT EPITHELIUM
    CYNTHIA HETH; Fiscal Year: 1993
    ..Isolated ROS and polystyrene latex spheres (PSL) will be used as particles for phagocytic challenge to differentiate changes which are specific only ..
  56. LASER KILLING OF FETAL NEURONS
    JEFFREY MACKLIS; Fiscal Year: 1990
    ..A newly developed latex nanosphere delivery system can deliver sufficient dye to targeted subpopulations of cells to allow selective ..
  57. BEHAVIORAL INTERVENTION FOR CONGENITAL CMV DISEASE
    Stuart Adler; Fiscal Year: 2001
    ..in both education groups will be given instructions about protective behaviors (frequent hand washing, wearing latex gloves) and risky behaviors to avoid (intimate contact with the child)...
  58. A Pilot Study of a Spiritually-Focused Intervention
    BRENDA COLE; Fiscal Year: 2005
    ..through a comprehensive questionnaire administered before and after the intervention, and two and four months latex as follow-up...
  59. Ultrasound monitored HIV rapid test
    SIMON BYSTRYAK; Fiscal Year: 2004
    ..of the agglutination process; (b) generation of microbubbles in the nodes of the standing acoustic wave, where the latex particle aggregates serve as microbubble nucleation centers; (c) the growth of the microbubbles in the ultrasonic ..
  60. POROSITY PREVENTION IN PROPHYLACTIC MEMBRANES
    DON GRAY; Fiscal Year: 1993
    b>Latex rubber articles in the form of condoms and gloves are used as barriers against the transmission of infectious diseases...
  61. DIAGNOSIS OF INFLAMMATORY DIARRHEA
    ROBERT CARMAN; Fiscal Year: 1992
    ..We will optimize a rapid agglutination assay for the detection of lactoferrin using antibody-coated latex particles and examine the stability of the marker in fecal specimens...
  62. BIOCHEMICAL STUDIES OF A MAJOR OPSONIC PROTEIN
    Janos Molnar; Fiscal Year: 1980
    ..We are using 125I-gelatin coated latex particles (g-Ltx) in conjunction with rat peritoneal macrophages...
  63. Unraveling the Molecular Mechanisms of Phagocytosis(RMI)
    Fabienne Paumet; Fiscal Year: 2005
    ..In this application, we seek to address these questions. By using a cell assay based on fluorescent latex beads, we will investigate 1- which compounds are influencing the internalization of different size particles and ..