cyanoacrylates

Summary

Summary: A group of compounds having the general formula CH2=C(CN)-COOR; it polymerizes on contact with moisture; used as tissue adhesive; higher homologs have hemostatic and antibacterial properties.

Top Publications

  1. pmc Use of tissue adhesives in the management of paediatric lacerations
    A Mattick
    Department of Accident and Emergency Department, The Royal Infirmary of Edinburgh, Lauriston Place, Edinburgh EH3 9YW, UK
    Emerg Med J 19:382-5. 2002
  2. ncbi Comparative study of suture and Cyanoacrylates in skin closure of rats
    Sandro Cilindro de Souza
    Adventist Education Institute, Capoeiruçu, Bahia, Brazil
    Acta Cir Bras 22:309-16. 2007
  3. ncbi [Cyanoacrylate adhesives for the synthesis of soft tissue]
    Sybele Saska
    Instituto de Quimica de Araraquara, Universidade Estadual Paulista, Sao Paulo, SP, Brasil
    An Bras Dermatol 84:585-92. 2009
  4. pmc Posttraumatic pseudoaneurysm in scalp treated by direct puncture embolization using N-butyl-2-cyanoacrylate: a case report
    Hee Jin Yang
    Department of Neurosurgery, Seoul National University Boramae Hospital, Seoul, Korea
    Korean J Radiol 6:37-40. 2005
  5. ncbi Cytotoxic effects of cyanoacrylates used as retrograde filling materials: an in vitro analysis
    Cledson Lima de Azevedo
    Department of Endodontics, School of Dentistry, University of Sao Paulo, Brazil
    Pesqui Odontol Bras 17:113-8. 2003
  6. doi Strong, low-density nanocomposites by chemical vapor deposition and polymerization of cyanoacrylates on aminated silica aerogels
    Dylan J Boday
    Materials Science and Engineering, University of Arizona, Tucson, Arizona 85721 0012, USA
    ACS Appl Mater Interfaces 1:1364-9. 2009
  7. ncbi The efficacy of cyanoacrylate-derived surgical adhesive for use in the repair of lacerations during competitive athletics
    A D Perron
    Department of Emergency Medicine, University of Virginia Health Sciences Center, Charlottesville 22906 0014, USA
    Am J Emerg Med 18:261-3. 2000
  8. ncbi Intratumoral injection of cyanoacrylate glue in head and neck paragangliomas
    Daniel Giansante Abud
    Department of Interventional Neuroradiology, Foundation Rothschild, Paris, France
    AJNR Am J Neuroradiol 25:1457-62. 2004
  9. ncbi Evaluation of a new liquid occlusive dressing for excisional wounds
    Adam J Singer
    Department of Emergency Medicine, Stony Brook University, Stony Brook, New York 11794, USA
    Wound Repair Regen 11:181-7. 2003
  10. ncbi The effect of a new tissue-adhesive wound dressing on the healing of traumatic abrasions
    J Quinn
    Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA
    Dermatology 201:343-6. 2000

Research Grants

  1. Omega-3 Fish Oil for Nonalcoholic Steatohepatitis
    Stephen Caldwell; Fiscal Year: 2007
  2. Engineering Tendon Grafts for Better Outcomes
    Chunfeng Zhao; Fiscal Year: 2010
  3. Effect of lipid modification on peripheral arterial disease (PAD)
    Christie Ballantyne; Fiscal Year: 2007
  4. Modified Hyaluronic Acid for Extrasynovial Tendon Graft
    Chunfeng Zhao; Fiscal Year: 2006
  5. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004

Detail Information

Publications171 found, 100 shown here

  1. pmc Use of tissue adhesives in the management of paediatric lacerations
    A Mattick
    Department of Accident and Emergency Department, The Royal Infirmary of Edinburgh, Lauriston Place, Edinburgh EH3 9YW, UK
    Emerg Med J 19:382-5. 2002
  2. ncbi Comparative study of suture and Cyanoacrylates in skin closure of rats
    Sandro Cilindro de Souza
    Adventist Education Institute, Capoeiruçu, Bahia, Brazil
    Acta Cir Bras 22:309-16. 2007
    ..To compare the biocompatibility of ethyl-cyanoacrylate (ECA) and octylcyanoacrylate (OCA) wound closures to sutures in rat skin...
  3. ncbi [Cyanoacrylate adhesives for the synthesis of soft tissue]
    Sybele Saska
    Instituto de Quimica de Araraquara, Universidade Estadual Paulista, Sao Paulo, SP, Brasil
    An Bras Dermatol 84:585-92. 2009
    ..Tissue adhesives have been used for the synthesis of wound due to their painless application and quick and easy handling...
  4. pmc Posttraumatic pseudoaneurysm in scalp treated by direct puncture embolization using N-butyl-2-cyanoacrylate: a case report
    Hee Jin Yang
    Department of Neurosurgery, Seoul National University Boramae Hospital, Seoul, Korea
    Korean J Radiol 6:37-40. 2005
    ..Direct puncture embolization was then performed, and the pseudoaneurysm was completely obliterated. Non-surgical treatment options for pseudoaneurysm are briefly discussed...
  5. ncbi Cytotoxic effects of cyanoacrylates used as retrograde filling materials: an in vitro analysis
    Cledson Lima de Azevedo
    Department of Endodontics, School of Dentistry, University of Sao Paulo, Brazil
    Pesqui Odontol Bras 17:113-8. 2003
    ..The aim of this study was to evaluate the cytotoxic effects of Histoacryl and other two homologue ethyl cyanoacrylates, Super Bonder and Ultrabond, on cultured fibroblasts, using the Trypan blue dye exclusion assay...
  6. doi Strong, low-density nanocomposites by chemical vapor deposition and polymerization of cyanoacrylates on aminated silica aerogels
    Dylan J Boday
    Materials Science and Engineering, University of Arizona, Tucson, Arizona 85721 0012, USA
    ACS Appl Mater Interfaces 1:1364-9. 2009
    ..220 g/cm(3) and up to 31 times stronger (flexural strength) than the precursor aerogel and about 2.3 times stronger than an unmodified silica aerogel of the same density...
  7. ncbi The efficacy of cyanoacrylate-derived surgical adhesive for use in the repair of lacerations during competitive athletics
    A D Perron
    Department of Emergency Medicine, University of Virginia Health Sciences Center, Charlottesville 22906 0014, USA
    Am J Emerg Med 18:261-3. 2000
    ..Of these 31, all had good results at 7 days following repair. Dermabond retained its strength, durability, and skin apposition when the athlete was allowed to reenter competition following wound repair...
  8. ncbi Intratumoral injection of cyanoacrylate glue in head and neck paragangliomas
    Daniel Giansante Abud
    Department of Interventional Neuroradiology, Foundation Rothschild, Paris, France
    AJNR Am J Neuroradiol 25:1457-62. 2004
    ..We report our experience with the preoperative devascularization of head and neck paragangliomas by using direct puncture and an intralesional injection of cyanoacrylate...
  9. ncbi Evaluation of a new liquid occlusive dressing for excisional wounds
    Adam J Singer
    Department of Emergency Medicine, Stony Brook University, Stony Brook, New York 11794, USA
    Wound Repair Regen 11:181-7. 2003
    ..The liquid occlusive dressing is an effective microbial barrier and hemostatic agent resulting in fewer foreign body reactions than hydrocolloid-treated wounds or controls...
  10. ncbi The effect of a new tissue-adhesive wound dressing on the healing of traumatic abrasions
    J Quinn
    Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, USA
    Dermatology 201:343-6. 2000
    ..Octylcyanoacrylate is a new medical-grade adhesive with antimicrobial properties. It forms a thin, flexible, occlusive bandage...
  11. ncbi A prospective comparison of octyl cyanoacrylate tissue adhesive (dermabond) and suture for the closure of excisional wounds in children and adolescents
    L Bernard
    Children's Hospital and HealthCenter, 3030 Children's Way, Suite 408, San Diego, CA 92123, USA
    Arch Dermatol 137:1177-80. 2001
    ..09). CONCLUSION: The cosmetic outcome of cutaneous excisional surgery wounds closed with standard suturing was found to be superior to that of wounds closed with octyl cyanoacrylate...
  12. ncbi The clinical characteristics, endoscopic treatment, and prognosis for patients presenting with duodenal varices
    Shigenaga Matsui
    Depertment of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka Sayama 589 8511, Japan
    Hepatogastroenterology 55:959-62. 2008
    ..This study investigated the clinical characteristics, endoscopic appearances, usefulness of endoscopic treatments, and survival of patients with duodenal varices...
  13. ncbi 2-octyl cyanoacrylate adhesive for conjunctival wound closure in rabbits
    Yuri M Kim
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, USA
    J Pediatr Ophthalmol Strabismus 40:152-5. 2003
    ..To evaluate the efficacy and histology of 2-octyl cyanoacrylate in conjunctival wound closure in rabbits...
  14. ncbi Cyanoacrylates for skin closure
    William H Eaglstein
    Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, FL 33136, USA
    Dermatol Clin 23:193-8. 2005
    b>Cyanoacrylates (CAs) were not widely adopted for medical use until recently because of lingering concerns regarding the initial tissue toxicities of the short-chain CAs...
  15. ncbi The use of tissue adhesive for skin closure in body contouring surgery
    Fabio Xerfan Nahas
    Universidade Federal de Sao Paulo EPM, Disciplina de Cirurgia Plástica, Brazil
    Aesthetic Plast Surg 28:165-9. 2004
    ..Abdominoplasty and mammoplasty are cosmetic surgeries that demand relatively more time for skin closure...
  16. doi Clinical characteristics and endoscopic treatment with cyanoacrylate injection in patients with duodenal varices
    Yingdi Liu
    Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China
    Scand J Gastroenterol 44:1012-6. 2009
    ..To summarize the clinical characteristics and evaluate the effectiveness of cyanoacrylate injection in patients with duodenal varices (DV)...
  17. ncbi A new acrylic tissue adhesive for conjunctival surgery: experimental study
    Jorge L Alio
    Ophthalmology Department, Miguel Hernandez University, Alicante, Spain
    Ophthalmic Res 35:306-12. 2003
    ..To evaluate the clinical efficacy and the clinical and histopathologic tolerance of a new acrylic tissue adhesive (ADAL-2) versus 8/0 polyglactin sutures (Vicryl) for its use in conjunctival surgery...
  18. ncbi An octyl-2-cyanoacrylate formulation speeds healing of partial-thickness wounds
    S C Davis
    Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA
    Dermatol Surg 27:783-8. 2001
    ..Occlusive dressings have been known to accelerate the rate of healing. Every year new dressings are being introduced in the marketplace...
  19. ncbi A prospective, randomized, controlled clinical trial of tissue adhesive (2-octylcyanoacrylate) versus standard wound closure in breast surgery
    R Gennari
    Department of Surgery, European Institute of Oncology, Milano, Italy
    Surgery 136:593-9. 2004
    ..To date, no studies have investigated tissue adhesive in breast surgery and costs. Our aim was to compare the tissue adhesive 2-octylcyanoacrylate (OCA) with standard suture in breast surgery...
  20. ncbi Dermabond skin closures for bilateral reduction mammaplasties: a review of 255 consecutive cases
    Gregory R Scott
    Department of Plastic Surgery, Kaiser Permanente San Diego Medical Center, CA 92110, USA
    Plast Reconstr Surg 120:1460-5. 2007
    ..The purpose of this study was to review a large series of 255 consecutive bilateral reduction mammaplasty patients to evaluate the safety and efficacy of Dermabond for these procedures...
  21. ncbi In vitro assessment of microbial barrier properties of Dermabond topical skin adhesive
    Shubhangi Bhende
    Corporate Microbiology and Sterilization Sciences, Ethicon, Somerville, New Jersey 08876, USA
    Surg Infect (Larchmt) 3:251-7. 2002
    ..The purpose of this study is to demonstrate that Dermabond Topical Skin Adhesive, 2-octylcyanoacrylate (a registered trademark of Ethicon) is an effective barrier against the penetration of microorganisms in an in vitro model...
  22. doi Cleft lip repair without suture removal
    T W Collin
    Department of Plastic and Reconstructive Surgery, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Plast Reconstr Aesthet Surg 62:1161-5. 2009
    ..Subjective and objective data were collected and are presented to justify the continued use of this technique in the Newcastle Cleft Lip and Palate Unit...
  23. ncbi A review of the literature on octylcyanoacrylate tissue adhesive
    Adam J Singer
    Department of Emergency Medicine, Stony Brook Health Sciences Center, L3 058, Stony Brook University, Stony Brook, NY 11794 8350, USA
    Am J Surg 187:238-48. 2004
    ..We reviewed animal and human studies that evaluated its use for a variety of surgical indications and specialties. We also performed a meta-analysis of all clinical trials using octylcyanoacrylate...
  24. ncbi Comparison of the bacteriostatic effects, corneal cytotoxicity, and the ability to seal corneal incisions among three different tissue adhesives
    Wei Li Chen
    Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan
    Cornea 26:1228-34. 2007
    ..To compare the bacteriostatic effects, corneal cytotoxicity, and ability to seal corneal incisions among fibrin glue and 2 commercially available cyanoacrylate derivatives: N-butyl cyanoacrylate and methoxypropyl cyanoacrylate...
  25. ncbi Use of Dermabond tissue adhesive in hand surgery
    N J Hancock
    Royal Hampshire County Hospital, Eastleigh and Winchester Hospitals NHS Trust, Winchester, UK
    J Wound Care 16:441-3. 2007
    ..To assess the efficacy and safety of a tissue adhesive for wound closure in elective hand surgery...
  26. ncbi Using Dermabond for wound closure in lumbar and cervical neurosurgical procedures
    Lance T Hall
    Department of Neurosurgery, West Virginia University, Morgantown, West Virginia 26506, USA
    Neurosurgery 56:147-50; discussion 147-50. 2005
    ..There are no published studies using Dermabond on lumbar or cervical procedures. This study was undertaken to determine whether Dermabond is safe and efficacious to use in these common neurosurgical procedures...
  27. ncbi Prospective randomized trial of skin adhesive versus sutures for closure of 217 laparoscopic port-site incisions
    Surena F Matin
    Cleveland Clinic Foundation Minimally Invasive Surgery Center, Cleveland Clinic Foundation, OH, USA
    J Am Coll Surg 196:845-53. 2003
    ....
  28. ncbi Octyl 2-cyanoacrylate for repair of peripheral nerve
    Angela Pineros-Fernandez
    Department of Plastic Surgery, University of Virginia Health System, Charlottesville, VA 22903 1351, USA
    Ann Plast Surg 55:188-95. 2005
    ..These results indicate that the use of octyl 2-cyanoacrylate adhesive for nerve anastomoses is safe and effective and may have benefits compared with the use of sutures...
  29. ncbi Efficacy of octyl-2-cyanoacrylate tissue glue in blepharoplasty. A prospective controlled study of wound-healing characteristics
    D Greene
    Division of Otolaryngology Head and Neck Surgery, Facial Plastic and Reconstructive Surgery, Stanford University Medical Center, Calif, USA
    Arch Facial Plast Surg 1:292-6. 1999
    ..To compare the surgical efficacy and wound-healing characteristics of the tissue adhesive octyl-2-cyanoacrylate (approved by the Food and Drug Administration) with traditional suture closure in upper blepharoplasty...
  30. ncbi Octyl 2-cyanoacrylate in sutureless surgery of extraocular muscles: an experimental study in the rabbit model
    B Ricci
    Department of Ophthalmology, Catholic University of Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 238:454-8. 2000
    ..Thus far, however, the results obtained with tissue adhesives such as the cyanoacrylates instead of sutures have been less than satisfactory.
  31. pmc A blinded, randomised, controlled trial of stapled versus tissue glue closure of neck surgery incisions
    D M Ridgway
    Scunthorpe General Hospital, Northern Lincolnshire and Goole Hospitals NHS Trust, Scunthorpe, UK
    Ann R Coll Surg Engl 89:242-6. 2007
    ..This randomised, controlled trial compares these parameters in closures using tissue glue (Dermabond, Ethicon, UK) and skin staples...
  32. ncbi A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations
    J Quinn
    Section of Emergency Medicine, University of Michigan, Ann Arbor 48109 0303, USA
    JAMA 277:1527-30. 1997
    ..To assess the effectiveness of a new tissue adhesive for laceration closure...
  33. ncbi Use of cyanoacrylate tissue adhesive under a diaper
    V J Ferlise
    Division of Urology, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    BJU Int 87:672-3. 2001
    ..The incisions were cosmetically identical at 3 months of follow-up. CONCLUSION: Cyanoacrylate adhesive is a safe and effective method of skin closure that can be used under a diaper...
  34. pmc Antibacterial properties of cyanoacrylate tissue adhesive: Does the polymerization reaction play a role?
    Ivana Lopes Romero
    Department of Ophthalmology, Santa Casa de Sao Paulo, Sao Paulo, Brazil
    Indian J Ophthalmol 57:341-4. 2009
    ..To ascertain if the polymerization reaction also contributes additionally to the antibacterial effects of two commonly used cyanoacrylate tissue adhesives...
  35. ncbi Antibacterial analysis in vitro of ethyl-cyanoacrylate against ocular pathogens
    Roberta Pereira de Almeida Manzano
    Department of Ophthalmology, Santa Casa de Sao Paulo, Sao Paulo, Brazil
    Cornea 25:350-1. 2006
    ..To analyze the antimicrobial properties of ethyl-cyanoacrylate (Superbonder, Loctite, Brazil) in vitro in different microorganisms related to corneal infections...
  36. ncbi Concomitant use of computer image guidance, linear or sigmoid incisions after minimal shave, and liquid wound dressing with 2-octyl cyanoacrylate for tumor craniotomy or craniectomy: analysis of 225 consecutive surgical cases with antecedent historical co
    Joon Cho
    Department of Neurosurgery, Konkuk University, Seoul, South Korea
    Neurosurgery 52:832-40; discussion 840-1. 2003
    ..Somerville, NJ) for tumor craniotomy or craniectomy in our attempt to optimize craniotomy or craniectomy for tumor...
  37. ncbi Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting
    Irène Brigger
    Laboratory of Biopharmacy and Pharmaceutical Technology, UMR Centre National de la Recherche Scientifique 8612, Faculty of Pharmacy, Chatenay Malabry, France
    J Pharmacol Exp Ther 303:928-36. 2002
    ..The exact underlying mechanism of such affinity deserves further investigation, since it was observed to be as important as specific interactions described for immunoliposomes with the blood-brain barrier...
  38. ncbi Preliminary in vitro evaluation of 2-octyl cyanoacrylate (Dermabond) to seal corneal incisions
    Gloria Y S Leung
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, People s Republic of China
    Cornea 24:998-9. 2005
    ..To compare the efficacy of Dermabond with conventional nylon sutures for sealing linear corneal incisions...
  39. doi Dermabond tissue adhesive versus Steri-Strips in unilateral cleft lip repair: an audit of infection and hypertrophic scar rates
    Andrew D H Wilson
    Department of Plastic Surgery, Frenchay Hospital, Frenchay, Bristol, United Kingdom
    Cleft Palate Craniofac J 45:614-9. 2008
    ..The purpose of this study was to compare the infection and hypertrophic scar rates in unilateral cleft lip repairs, having had Steri-Strips or Dermabond tissue glue applied across the repair as the final stage...
  40. doi Persistent trigeminal artery terminating in the posterior inferior cerebellar artery: case report
    Saad Ali
    Department of Radiology, Section of Neuroradiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Neurosurgery 62:E746-8; discussion E746-8. 2008
    ..An unusual case of a patient with a trigeminal artery originating from the internal carotid artery and terminating as the dominant hemispheric branch of the posterior inferior cerebellar artery is presented...
  41. ncbi Cellular, histomorphologic, and clinical characteristics of a new octyl-2-cyanoacrylate skin adhesive
    Axel Nitsch
    Georg August University, University Hospital and Medical School, Goettingen, Germany
    Aesthetic Plast Surg 29:53-8. 2005
    Short-chained cyanoacrylates have been used for many years for topical skin closure...
  42. ncbi Liquid embolic agents in the treatment of intracranial arteriovenous malformations
    Jay U Howington
    Department of Neurosurgery and Toshiba Stroke Research Center, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 3 Gates Circle, Buffalo, NY 14209, USA
    Neurosurg Clin N Am 16:355-63, ix-x. 2005
  43. ncbi Embolotherapy of an arterioportal fistula
    Qi Chen
    Department of Radiology, Maimonides Medical Center, 4802 10th Avenue, Brooklyn, NY 11219, USA
    Cardiovasc Intervent Radiol 30:1047-51. 2007
    ..On the day following the procedure, the patient reported total remission of the abdominal pain and diarrhea. These results were maintained at 3 months follow-up...
  44. ncbi A novel technique and new grading scale for the embolization of cerebral vascular malformations
    Arun P Amar
    Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut 06520 8082, USA
    Neurosurgery 59:S158-62; discussion S3-13. 2006
    ..The authors sought to overcome these obstacles by developing a technique to enhance glue penetration into the fistula or AVM nidus itself...
  45. ncbi Primary treatment of an indirect carotid cavernous fistula by injection of N-butyl cyanoacrylate in the dural wall of the cavernous sinus
    Ali Shaibani
    Department of Radiology, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, USA
    Surg Neurol 67:403-8; discussion 408. 2007
    ..Endovascular treatment is the treatment of choice, but because of their heterogeneous etiology and anatomy, an appropriate treatment plan must be tailored for each patient...
  46. ncbi Closure of long surgical incisions with a new formulation of 2-octylcyanoacrylate tissue adhesive versus commercially available methods
    Phillip N V Blondeel
    University Hospital Gent, De Pintelaan 185, 2K12C, B 9000, Gent, Belgium
    Am J Surg 188:307-13. 2004
    ..Topical 2-octylcyanoacrylate tissue adhesive is an alternative to traditional devices for closing short surgical incisions...
  47. ncbi Octyl-2-cyanoacrylate tissue glue (Dermabond) versus Monocryl 6 x 0 Sutures in lip closure
    Paul H M Spauwen
    Department of Plastic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
    Cleft Palate Craniofac J 43:625-7. 2006
    ..To assess the value of octyl-2-cyanoacrylate tissue glue in lip closure versus Monocryl stitches...
  48. ncbi Microneural anastomosis using cyanoacrylate adhesives
    B H Choi
    Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, South Korea
    Int J Oral Maxillofac Surg 33:777-80. 2004
    ..It was concluded that the cyanoacrylate repair deserves to be considered as an alternative to the conventional suture technique in microneural anastomosis...
  49. ncbi Pulmonary embolization of 2-octyl cyanoacrylate after endoscopic injection therapy for gastric variceal bleeding
    Otis B Rickman
    Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Mayo Clin Proc 79:1455-8. 2004
    ..The radiologist should be alerted so that the appropriate radiographic settings are used to make the diagnosis...
  50. ncbi [Dermabond--local skin bandage]
    R Velev
    Akush Ginekol (Sofiia) 45:22-4. 2006
  51. ncbi Low morbidity associated with use of n-butyl cyanoacrylate liquid adhesive for preoperative transarterial embolization of central nervous system tumors
    Louis J Kim
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
    Neurosurgery 59:98-104; discussion 98-104. 2006
    ..To determine the safety and efficacy of preoperative embolization of central nervous system tumors with n-butyl cyanoacrylate (NBCA) liquid adhesive...
  52. ncbi Cardiac device implant wound closure with 2-octyl cyanoacrylate
    Roman Pachulski
    Alamo Heart Associates, San Antonio, Texas
    J Interv Cardiol 18:185-7. 2005
    ..6%) of the suture group (P=NS). In cardiac device implant closure 2-OCA obviated the need for topical antibiotics and dressing materials while facilitating wound care without increased complications...
  53. ncbi A modified percutaneous transhepatic variceal embolization with 2-octyl cyanoacrylate versus endoscopic ligation in esophageal variceal bleeding management: randomized controlled trial
    Chun Qing Zhang
    Department of Gastroenterology, Shandong Provincial Hospital, Jinan, Shandong, China
    Dig Dis Sci 53:2258-67. 2008
    ..We compared this PTVE with endoscopic band ligation (EVL) in the treatment of esophageal variceal bleeding...
  54. ncbi Intracranial mycotic aneurysm due to infective endocarditis--successful NBCA glue embolisation
    S K Misser
    Inkosi Albert Luthuli Central Hospital, Durban
    S Afr Med J 95:397-9, 403-4. 2005
  55. ncbi Wound approximation with tissue glue in circumcision
    Keramettin Ugur Ozkan
    Department of Pediatric Surgery, Kahramanmaras Sutcuimam University Medical Faculty, Kahramanmaras, Turkey
    Int J Urol 12:374-7. 2005
    ..To assess the feasibility of using tissue glue in the approximation of circumcision wounds in children...
  56. ncbi Octyl-2-cyanoacrylate tissue adhesive in external dacryocystorhinostomy
    Steven H McKinley
    Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA
    Ophthal Plast Reconstr Surg 21:197-200. 2005
    ..To review our experience using octyl-2-cyanoacrylate for closing the cutaneous incision in external dacryocystorhinostomy (DCR)...
  57. ncbi Prevention of systemic embolization associated with treatment of gastric fundal varices
    Akio Matsumoto
    Mayo Clin Proc 80:705. 2005
  58. ncbi [Octylcyanoacrylate (Dermabond) for skin closure at the time of head and neck surgery: a longitudinal prospective study]
    O Laccourreye
    Service d otorhinolaryngologie et de chirurgie cervicofaciale, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris V, 75015 Paris, France
    Ann Chir 130:624-30. 2005
    ..A prospective non-randomised evaluation of the octyl-2-cyanoacrylate (Dermabond) for skin closure in head and neck surgery...
  59. ncbi Evaluation of an absorbable cyanoacrylate adhesive as a suture line sealant
    Peter I Ellman
    Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Surg Res 125:161-7. 2005
    ..A novel cyanoacrylate compound with less tissue reactivity was recently developed. The objective of this study was to assess this novel cyanoacrylate compound for the use as vascular suture line sealant...
  60. ncbi Embolization of type 2 endoleaks after endovascular repair of abdominal aortic aneurysms with use of cyanoacrylate with or without coils
    S William Stavropoulos
    Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19010, USA
    J Vasc Interv Radiol 16:857-61. 2005
    ..Aneurysm size remained unchanged in four patients (44%), decreased in four patients (44%), and increased in one patient (11%). No complications occurred. Initial results with the use of NBCA for endoleak embolization are encouraging...
  61. ncbi Adverse events of sutures: possible interactions of biomaterials?
    Rene G Holzheimer
    Chirurgische Praxisklinik, Sauerlach München, Germany
    Eur J Med Res 10:521-6. 2005
    ..We do not know the cause for this change. For clarification evaluation of the tissue reactions of these biomaterials including possible interactions or combined reactions should be done...
  62. ncbi A comparison of three methods of wound closure following arthroplasty: a prospective, randomised, controlled trial
    R J K Khan
    Sir Charles Gairdner Hospital, Perth 6009, Western Australia
    J Bone Joint Surg Br 88:238-42. 2006
    ..We consider that skin staples are the skin closure of choice for both hip and knee replacements...
  63. ncbi The management of vein of Galen aneurysmal malformations
    Pierre L Lasjaunias
    Department of Diagnostic and Interventional Neuroradiology, Hopital de Bicetre, Le Kremlin Bicetre, France
    Neurosurgery 59:S184-94; discussion S3-13. 2006
    ....
  64. ncbi Transcranial puncture through the parietal and mastoid foramina for the treatment of dural fistulas. Report of four cases
    Rene Chapot
    Department of Neuroradiology, hôpital Dupuytren, Limoges, France
    J Neurosurg 106:912-5. 2007
    ..Complete cure of the DAVF was attained in all patients after injection of acrylic glue...
  65. ncbi A preliminary study of applying chemical biliary duct embolization to chemical hepatectomy in rats
    Fu Yu Li
    Department of Hepatobiliary Surgery, West China Hospital of Sichuan University, Chengdu 610041, China
    Dig Dis Sci 50:1161-5. 2005
    ..In conclusion, CBDE might be a promising approach for achieving the effects of chemical hepatectomy. The combination of phenol and cyanoacrylate potentially acted as a more effective agent for biliary duct embolization...
  66. ncbi Resistance and stability of a new method for bonding biological materials using sutures and biological adhesives
    J M García Páez
    Servicio de Cirugia Experimental, Clinica Puerta de Hierro, San Martin de Porres 4, 28035 Madrid, Espana
    J Biomater Appl 19:215-36. 2005
    ..These results need to be confirmed in future studies as they may be of value in the design and manufacture of cardiac bioprostheses...
  67. ncbi A prospective randomized trial comparing 2-octyl cyanoacrylate to conventional suturing in closure of laparoscopic cholecystectomy incisions
    Navid Jallali
    Department of General Surgery, Addenbrooke s Hospital, Cambridge, United Kingdom
    J Laparoendosc Adv Surg Tech A 14:209-11. 2004
    ..To compare 2-octyl cyanoacrylate (Dermabond) with conventional suturing for closure of laparoscopic cholecystectomy (LC) wounds in a prospective randomized controlled trial...
  68. ncbi A prospective comparison of octyl-2-cyanoacrylate and suture in standardized facial wounds
    J G K Handschel
    Department of Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstr 5, D 40225 Dusseldorf, Germany
    Int J Oral Maxillofac Surg 35:318-23. 2006
    ....
  69. ncbi Sutureless Lichtenstein: first results of a prospective randomised clinical trial
    Christian Helbling
    Klinik für Chirurgie Kantonsspital Aarau, Buchserstrasse, Switzerland
    Hernia 7:80-4. 2003
    ..The results in group 2 were excellent, and there was no difference vs group 1. Furthermore, there was a tendency for better results in group 2. These results are very promising and justify a continuation of the study...
  70. ncbi Subcuticular closure versus Dermabond: a prospective randomized trial
    Erin F Switzer
    Department of Surgery, Eisenhower Army Medical Center, Fort Gordon, Georgia 30905, USA
    Am Surg 69:434-6. 2003
    ..Based on these findings we do not feel Dermabond is an acceptable alternative to subcuticular suture closure in inguinal herniorrhaphy incisions...
  71. ncbi Sutureless colonic anastomosis in the rat: a randomized controlled study
    I Kanellos
    Fourth Department of Surgery, Aristotle University, Antheon 1, Panorama, GR 55236 Thessaloniki, Greece
    Tech Coloproctol 6:143-6. 2002
    ..05). In conclusion, 2-octyl cyanoacrylate provides, under experimental conditions, a sutureless anastomosis equal in healing to the conventionally sutured one. The outcome may differ under demanding clinical situations...
  72. ncbi Comparing wound closure using tissue glue versus subcuticular suture for pediatric surgical incisions: a prospective, randomised trial
    C C P Ong
    Department of Pediatric Surgery, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore 229899
    Pediatr Surg Int 18:553-5. 2002
    ..68). No patient reported any rash, wound infection, or dehiscence. Tissue glue is easy to use with no complications and has equivalent cosmetic results, but is not faster than a subcuticular suture...
  73. ncbi Randomized study of the effectiveness of closing laparoscopic trocar wounds with octylcyanoacrylate, adhesive papertape or poliglecaprone
    S Maartense
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Br J Surg 89:1370-5. 2002
    ..This study was performed to analyse the efficacy of octylcyanoacrylate, a new tissue adhesive, adhesive papertape and poliglecaprone for wound closure in laparoscopy...
  74. ncbi [Long-term results of suture-free cutanous wound closure in head and neck incisions with octylcyanoacrylate topival skin adhesive]
    W E Rojas
    Klinik für Hals Nasen Ohrenheilkunde und Plastische Kopf und Halschirurgie der RWTH Aachen, Germany
    Laryngorhinootologie 81:644-8. 2002
    ..Cyanoacrylate monomers have been developed for use as skin adhesives. So far, little is known about long-term results concerning functional and aesthetic results of wound closure with octylcyanoacrylate in head and neck region...
  75. ncbi Patch-and-glue technique for left ventricular free wall rupture
    Pasquale Totaro
    Ann Thorac Surg 74:294-5; author reply 295-6. 2002
  76. ncbi Coronary end-to-side sleeve anastomosis using adhesive in off-pump bypass grafting in the pig
    Marc P Buijsrogge
    Heart Lung Center Utrecht, University Medical Center Utrecht, The Netherlands
    Ann Thorac Surg 73:1451-6. 2002
    ..In the exploration of facilitated coronary anastomosis strategies, we assessed a new octylcyanoacrylate adhesive in combination with a modified end-to-side sleeve anastomosis in off-pump bypass grafting in the pig...
  77. ncbi Arterial embolization of unresectable hepatocellular carcinoma with use of microspheres, lipiodol, and cyanoacrylate
    Thomas Rand
    Department of Angiography and Interventional Radiology, University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Cardiovasc Intervent Radiol 28:313-8. 2005
    ..TAE with the use of microspheres and Lipiodol and cyanoacrylate for unresectable HCC is a feasible treatment modality. Bland embolization with the use of microspheres can be used in patients for whom chemoembolization is not desired...
  78. ncbi Processes involved in the development of latent fingerprints using the cyanoacrylate fuming method
    L A Lewis
    Development Chemists, Analytical Chemistry Organization, Lockheed Martin Energy Systems, Inc, Oak Ridge, TN, USA
    J Forensic Sci 46:241-6. 2001
    ..When heat is used to accelerate the fuming process, typically a period of 2 min is required to develop the print. The optimum development time depends upon the concentration of cyanoacrylate vapors within the enclosure...
  79. ncbi Sutureless coronary anastomosis with an anastomotic device and tissue adhesive in off-pump porcine coronary bypass grafting
    Marc P Buijsrogge
    Heart Lung Center Utrecht, University Medical Center Utrecht, The Netherlands
    J Thorac Cardiovasc Surg 123:788-94. 2002
    ....
  80. pmc Tissue adhesive with adhesive strips for wound closure
    P Atkinson
    Emerg Med J 20:498. 2003
  81. ncbi [Percutaneous transhepatic varices embolization with cyanoacrylate in the treatment of varices]
    Chun Qing Zhang
    Department of Gastroenterology, Shandong Provincial Hospital, Jinan 250021, China
    Zhonghua Yi Xue Za Zhi 87:3389-93. 2007
    ..To test the safety and validity of percutaneous transhepatic variceal embolization (PTVE) with tissue adhesive cyanoacrylate...
  82. ncbi A pilot study of 2-octyl cyanoacrylate injection for treatment of gastric fundal varices in humans
    Daniel S Rengstorff
    Interventional Endoscopy Service, California Pacific Medical Center, San Francisco, California 94115, USA
    Gastrointest Endosc 59:553-8. 2004
    ..This pilot study prospectively evaluated the efficacy and safety of 2-octyl cyanoacrylate injection for treatment of gastric fundal varices...
  83. pmc Octylcyanoacrylate skin closure in laparoscopy
    Michael J Sebesta
    Wilford Hall Medical Center, Lackland AFB, Texas 78326, USA
    JSLS 8:9-14. 2004
    ..Octylcyanoacrylate (Dermabond) is a dermal bond useful in closing surgical skin incisions. We compared skin octylcyanoacrylate with subcuticular skin sutures to close laparoscopic trocar sites...
  84. ncbi N-butyl cyanoacrylate embolization for control of acute arterial hemorrhage
    John William Kish
    Department of Radiology, Los Angeles County and University of Southern California Medical Center, 90064, USA
    J Vasc Interv Radiol 15:689-95. 2004
    ..To report the initial clinical experience with the use of n-butyl cyanoacrylate (NBCA) for embolization of acute arterial hemorrhage from varied etiologies and at varied anatomic sites...
  85. ncbi A new technique of tissue repair for ophthalmic surgery
    Grant T Hoffman
    Biomedical Engineering Program, Rose Hulman Institute of Technology, Terre Haute, IN 47803, USA
    Biomed Sci Instrum 40:57-63. 2004
    ..Future experiments will examine the optimization of application parameters and detail tensile strength time course studies...
  86. ncbi When endoscopic therapy or pharmacotherapy fails to control variceal bleeding: what should be done? Immediate control of bleeding by TIPS?
    Martin Rossle
    Praxiszentrum, Bertoldstrasse 48, 79098 Freiburg, Germany
    Langenbecks Arch Surg 388:155-62. 2003
    ..In the case of ectopic varices terlipressin and cyanoacrylate embolization (if varices can be reached by endoscope) are in use...
  87. ncbi Randomized controlled comparison of cosmetic outcomes of simple facial lacerations closed with Steri Strip Skin Closures or Dermabond tissue adhesive
    William T Zempsky
    Department of Pediatrics, Connecticut Children s Medical Center, University of Connecticut School of Medicine, Hartford, CT 06106, USA
    Pediatr Emerg Care 20:519-24. 2004
    ..To compare the short-term complications and long-term cosmetic outcomes of simple facial lacerations closed with 3M Steri Strip Skin Closures or Dermabond...
  88. ncbi Octylcyanoacrylate skin closure in laparoscopy
    Michael J Sebesta
    Department of Urology MCSU, Wilford Hall Medical Center, 2200 Bergquist Drive, Suite 1, Lackland AFB, TX 78326, USA
    J Endourol 17:899-903. 2003
    ..Octylcyanoacrylate (Dermabond) is a tissue "glue" useful in closing surgical skin incisions. We compared skin octylcyanoacrylate with subcuticular skin sutures to close laparoscopic trocar sites...
  89. ncbi Percutaneous puncture and pre-operative cyanoacrylate obliteration of a traumatic false aneurysm of an angular artery branch
    F Huang
    Departments of Plastic Surgery and Radiology, Chang Gung University, Chang Gung Memorial Hospital, 123, Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien 833, Taiwan
    Br J Radiol 76:746-9. 2003
    ..Intralesional obliteration with cyanoacrylate was subsequently performed smoothly. Succeeding excision was easy and the cosmetic outcome was excellent...
  90. ncbi In vitro and in vivo studies for modified ethyl cyanoacrylate regimens for sclerotherapy
    J C Lin
    Department of Chemical Engineering, National Cheng Kung University, Tainan, Taiwan 70101, ROC
    J Biomed Mater Res 53:799-805. 2000
    b>Cyanoacrylates have known for their ability to polymerize rapidly in the presence of traces of weakly basic moieties such as water...
  91. ncbi Occupational asthma due to acrylates in a graphic arts worker
    I Reig Rincon de Arellano
    Allergy Service, Hospital Clinico San Carlos, Madrid, Spain
    Allergol Immunopathol (Madr) 34:32-6. 2006
    ..Currently there are various types of acrylic compounds: acrylates, cyanoacrylates (such as tissue adhesives and home glues), and methacrylates (prostheses and dental and orthopedic fillings)...
  92. ncbi Microcatheter adhesion of cyanoacrylates: comparison of normal butyl cyanoacrylate to 2-hexyl cyanoacrylate
    J D Barr
    Department of Radiology, Penn State University College of Medicine, Milton S Hershey Medical Center, Hershey, USA
    J Vasc Interv Radiol 10:165-8. 1999
    ..To compare the catheter adhesion properties of 2-hexyl cyanoacrylate (Neuracryl M), a new agent, to those of normal butyl cyanoacrylate (Histoacryl), the most widely used liquid acrylic agent for microcatheter embolization...
  93. doi [An update on the use of tissue adhesives in ophthalmology]
    L Vera
    Service d Ophtalmologie, Hopital Charles Nicolle, boulevard Gambetta, Rouen, France
    J Fr Ophtalmol 32:290-305. 2009
    ..Among the currently available adhesives, synthetic glues are mainly represented by cyanoacrylates and biologic glues by fibrin-based adhesives...
  94. ncbi [Contact dermatitis caused by acrylates among 8 workers in an elevator factory]
    J L Pérez-Formoso
    Instituto de Salud Laboral Asepeyo Cartuja, Sevilla, Espana
    Actas Dermosifiliogr 101:336-40. 2010
    ..One of their main features is the ability to undergo polymerization. The most commonly used acrylic compounds are cyanoacrylates, methacrylates, and acrylates.
  95. ncbi Reducing needle-stick injuries with the use of 2-octyl cyanoacrylates for laceration repair
    C A Gordon
    J Am Acad Nurse Pract 13:10-2. 2001
    To describe the effectiveness of 2-octyl cyanoacrylates (2-OCA) for repair of lacerations, reduction of needle-stick injuries to health care providers, patient satisfaction, and overall cost reduction.
  96. ncbi [Transient ischemic attacks as the only manifestation of a dural arteriovenous fistula]
    F Delgado-Acosta
    Hospital Universitario Reina Sofia, Cordoba, Espana
    Rev Neurol 37:931-4. 2003
    ..Transient ischemic attacks (TIA), as the only clinical manifestation of a dural arteriovenous malformation, are very seldom seen in clinical practice...
  97. pmc Endovascular treatment of brain arteriovenous malformations using onyx: preliminary results of a prospective multicenter study
    L Pierot
    Department of Radiology, Hôpital Maison Blanche Reims, France
    Interv Neuroradiol 11:159-64. 2005
    ..Several embolic agents have been proposed for embolization of brain AVMs like particles or cyanoacrylates. The main disadvantage of particles is the high frequency of recanalization...
  98. ncbi Effects of a mixture of a low concentration of n-butylcyanoacrylate and ethiodol on tissue reactions and the permanence of arterial occlusion after embolization
    A Sadato
    Toshiba Stroke Research Center, Department of Neurosurgery, State University of New York at Buffalo, USA
    Neurosurgery 47:1197-203; discussion 1204-5. 2000
    b>Cyanoacrylates are the most commonly used liquid embolic agents...
  99. doi Hemostats, sealants, and adhesives: components of the surgical toolbox
    William D Spotnitz
    The Surgical Therapeutic Advancement Center, Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 1370, USA
    Transfusion 48:1502-16. 2008
    ..sealants as represented by fibrin sealants and polyethylene glycol hydrogels; and adhesives as represented by cyanoacrylates and albumin cross-linked with glutaraldehyde...
  100. doi Use of cyanoacrylate glue for the closure of uterine incisions
    Mustafa Basaran
    Zonguldak Karaelmas University Faculty of Medicine, Department of Obstetrics and Gynecology, Zonguldak, Turkey
    Minim Invasive Ther Allied Technol 18:217-20. 2009
    ..b>Cyanoacrylates are a group of molecules used as industrial adhesives. Newer cyanoacrylates are widely used in medicine...
  101. ncbi Allergic cutaneous diseases in hairdressers
    M Ferrari
    Unità Operativa di Medicina Ambientale e Medicina Occupazionale, Fondazione Salvatore Maugeri, IRCCS, Via Ferrata 4, 27100 Pavia, Italy
    Med Lav 96:102-18. 2005
    ..Several cases of allergic contact dermatitis and contact urticaria in hairdressers have been described over the last few years...

Research Grants12

  1. Omega-3 Fish Oil for Nonalcoholic Steatohepatitis
    Stephen Caldwell; Fiscal Year: 2007
    ....
  2. Engineering Tendon Grafts for Better Outcomes
    Chunfeng Zhao; Fiscal Year: 2010
    ..This research proposal is to develop a novel method for engineering tendon surfaces to improve the outcomes of tendon reconstruction leading towards restoration of normal hand function. ..
  3. Effect of lipid modification on peripheral arterial disease (PAD)
    Christie Ballantyne; Fiscal Year: 2007
    ..Finally, these studies will advance our understanding of the molecular mechanisms of inflammation and thrombosis associated with aggressive lipid modification. ..
  4. Modified Hyaluronic Acid for Extrasynovial Tendon Graft
    Chunfeng Zhao; Fiscal Year: 2006
    ..abstract_text> ..
  5. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004
    ..We hypothesize these genes can be used to modulate the biology of adult wound healing. This first step will form our basis for developing treatment to induce scarless healing. ..