plant oils

Summary

Summary: Oils derived from plants or plant products.

Top Publications

  1. ncbi Direct analysis of total antioxidant activity of olive oil and studies on the influence of heating
    N Pellegrini
    Institute of Hygiene, University of Parma, Parma, Italy
    J Agric Food Chem 49:2532-8. 2001
  2. ncbi Dietary virgin olive oil reduces oxidative stress and cellular damage in rat brain slices subjected to hypoxia-reoxygenation
    J A Gonzalez-Correa
    Laboratorio de Investigaciones Antitrombóticas e Isquemia Tisular LIAIT, Department of Pharmacology, School of Medicine, University of Malaga, Campus de Teatinos s n, 29071, Malaga, Spain
    Lipids 42:921-9. 2007
  3. ncbi The impact of olive oil consumption pattern on the risk of acute coronary syndromes: The CARDIO2000 case-control study
    Meropi D Kontogianni
    Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece
    Clin Cardiol 30:125-9. 2007
  4. ncbi Tyrosol, the major extra virgin olive oil compound, restored intracellular antioxidant defences in spite of its weak antioxidative effectiveness
    Roberta Di Benedetto
    National Centre for Food Quality and Risk Assessment, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Nutr Metab Cardiovasc Dis 17:535-45. 2007
  5. ncbi Oil content of Arabidopsis seeds: the influence of seed anatomy, light and plant-to-plant variation
    Yonghua Li
    Department of Plant Biology, Michigan State University, East Lansing, 48824 1312, USA
    Phytochemistry 67:904-15. 2006
  6. ncbi A comparative linkage map of oilseed rape and its use for QTL analysis of seed oil and erucic acid content
    D Qiu
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 1 Shizishan, 430070, Wuhan, China
    Theor Appl Genet 114:67-80. 2006
  7. doi Palm tocotrienol exerted better antioxidant activities in bone than alpha-tocopherol
    Sandra Maniam
    Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
    Basic Clin Pharmacol Toxicol 103:55-60. 2008
  8. pmc Genotype-specific responses in Atlantic salmon (Salmo salar) subject to dietary fish oil replacement by vegetable oil: a liver transcriptomic analysis
    Sofia Morais
    Institute of Aquaculture, University of Stirling, UK
    BMC Genomics 12:255. 2011
  9. ncbi Increasing the flow of carbon into seed oil
    Randall J Weselake
    Agricultural Lipid Biotechnology Program Department of Agricultural, Food and Nutritional Science University of Alberta, Edmonton, Alberta, Canada T6G 2P5
    Biotechnol Adv 27:866-78. 2009
  10. ncbi Maternal control of seed oil content in Brassica napus: the role of silique wall photosynthesis
    Wei Hua
    Key Laboratory of Oil Crop Biology of the Ministry of Agriculture, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China
    Plant J 69:432-44. 2012

Detail Information

Publications338 found, 100 shown here

  1. ncbi Direct analysis of total antioxidant activity of olive oil and studies on the influence of heating
    N Pellegrini
    Institute of Hygiene, University of Parma, Parma, Italy
    J Agric Food Chem 49:2532-8. 2001
    ..Heating experiments suggest that polyphenols from EVOO are effective stabilizers of alpha-tocopherol during olive oil heating, thus contributing to the nutritional value of cooked foods...
  2. ncbi Dietary virgin olive oil reduces oxidative stress and cellular damage in rat brain slices subjected to hypoxia-reoxygenation
    J A Gonzalez-Correa
    Laboratorio de Investigaciones Antitrombóticas e Isquemia Tisular LIAIT, Department of Pharmacology, School of Medicine, University of Malaga, Campus de Teatinos s n, 29071, Malaga, Spain
    Lipids 42:921-9. 2007
    ..It reduced oxidative stress and modulated the inducible isoform of nitric oxide synthase, diminishing platelet aggregation and protecting the brain from the effects of hypoxia-reoxygenation...
  3. ncbi The impact of olive oil consumption pattern on the risk of acute coronary syndromes: The CARDIO2000 case-control study
    Meropi D Kontogianni
    Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece
    Clin Cardiol 30:125-9. 2007
    ..The aim of the present study was to evaluate the association between the pattern of edible oils and fats consumption and the prevalence of a first, nonfatal event of an acute coronary syndrome (ACS) in a Greek sample...
  4. ncbi Tyrosol, the major extra virgin olive oil compound, restored intracellular antioxidant defences in spite of its weak antioxidative effectiveness
    Roberta Di Benedetto
    National Centre for Food Quality and Risk Assessment, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Nutr Metab Cardiovasc Dis 17:535-45. 2007
    ..This study compared the protective effects of tyrosol and hydroxytyrosol, two biophenols greatly different in antioxidant power, on J774 A.1-mediated oxidation of LDL...
  5. ncbi Oil content of Arabidopsis seeds: the influence of seed anatomy, light and plant-to-plant variation
    Yonghua Li
    Department of Plant Biology, Michigan State University, East Lansing, 48824 1312, USA
    Phytochemistry 67:904-15. 2006
    ....
  6. ncbi A comparative linkage map of oilseed rape and its use for QTL analysis of seed oil and erucic acid content
    D Qiu
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 1 Shizishan, 430070, Wuhan, China
    Theor Appl Genet 114:67-80. 2006
    ..The results provide new insights into the genetic control of seed oil and erucic acid content in oilseed rape, and demonstrate the utility of the linkage map and population...
  7. doi Palm tocotrienol exerted better antioxidant activities in bone than alpha-tocopherol
    Sandra Maniam
    Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
    Basic Clin Pharmacol Toxicol 103:55-60. 2008
    ..This study suggests that palm tocotrienol plays an important role in preventing imbalance in bone metabolism due to free radicals...
  8. pmc Genotype-specific responses in Atlantic salmon (Salmo salar) subject to dietary fish oil replacement by vegetable oil: a liver transcriptomic analysis
    Sofia Morais
    Institute of Aquaculture, University of Stirling, UK
    BMC Genomics 12:255. 2011
    ..This study investigates the influence of genotype on transcriptomic responses to sustainable feeds in Atlantic salmon...
  9. ncbi Increasing the flow of carbon into seed oil
    Randall J Weselake
    Agricultural Lipid Biotechnology Program Department of Agricultural, Food and Nutritional Science University of Alberta, Edmonton, Alberta, Canada T6G 2P5
    Biotechnol Adv 27:866-78. 2009
    ....
  10. ncbi Maternal control of seed oil content in Brassica napus: the role of silique wall photosynthesis
    Wei Hua
    Key Laboratory of Oil Crop Biology of the Ministry of Agriculture, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China
    Plant J 69:432-44. 2012
    ..Taken together, our results highlight an important role of silique wall photosynthesis in the regulation of seed oil content in terms of maternal effects...
  11. pmc Transcriptome analysis of the oil-rich seed of the bioenergy crop Jatropha curcas L
    Gustavo G L Costa
    Centre for Molecular Biology and Genetic Engineering, State University of Campinas, UNICAMP, Campinas, SP, Brazil
    BMC Genomics 11:462. 2010
    ..As a non-food, drought-resistant and oil-rich crop, Jatropha curcas L. fulfils many of the requirements for biofuel production...
  12. ncbi Anti-atherogenic effects of seabuckthorn (Hippophaea rhamnoides) seed oil
    M Basu
    Defence Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, Delhi 110054, India
    Phytomedicine 14:770-7. 2007
    ..These observations suggest that supercritical CO(2) extracted SBT seed oil has significant anti-atherogenic and cardioprotective activity...
  13. pmc DGAT1 and PDAT1 acyltransferases have overlapping functions in Arabidopsis triacylglycerol biosynthesis and are essential for normal pollen and seed development
    Meng Zhang
    Department of Plant Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 21:3885-901. 2009
    ....
  14. ncbi Metabolic engineering of fatty acid biosynthesis in plants
    Jay J Thelen
    Department of Plant Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Metab Eng 4:12-21. 2002
    ..plant transformation technology, metabolic engineering of oilseed fatty acids has become possible and transgenic plant oils represent some of the first successes in design of modified plant products...
  15. ncbi WRINKLED1 encodes an AP2/EREB domain protein involved in the control of storage compound biosynthesis in Arabidopsis
    Alex Cernac
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 1319, USA
    Plant J 40:575-85. 2004
    ..This effect depended upon the presence of glucose in the growth medium or other sugars readily metabolized to glucose. Oil-accumulating seedlings showed aberrant development consistent with a prolonged embryonic state...
  16. pmc Regulatory mechanisms underlying oil palm fruit mesocarp maturation, ripening, and functional specialization in lipid and carotenoid metabolism
    Timothy J Tranbarger
    Institut de Recherche pour le Developpement, UMR Diversité et Adaptation et Développement des Plantes, 34394 Montpellier Cedex 5, France
    Plant Physiol 156:564-84. 2011
    ..Our results suggest that divergence has occurred in the regulatory components in this monocot fruit compared with those identified in the dicot tomato (Solanum lycopersicum) fleshy fruit model...
  17. ncbi Antimicrobial activity of essential oils and other plant extracts
    K A Hammer
    Department of Microbiology, The University of Western Australia, Nedlands, Western Australia
    J Appl Microbiol 86:985-90. 1999
    The antimicrobial activity of plant oils and extracts has been recognized for many years. However, few investigations have compared large numbers of oils and extracts using methods that are directly comparable...
  18. ncbi Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
    Sven Eric Jordt
    Department of Cellular and Molecular Pharmacology University of California, San Francisco, California 94143 2140, USA
    Nature 427:260-5. 2004
    ..These findings identify a cellular and molecular target for the pungent action of mustard oils and support an emerging role for TRP channels as ionotropic cannabinoid receptors...
  19. pmc Seed-specific over-expression of an Arabidopsis cDNA encoding a diacylglycerol acyltransferase enhances seed oil content and seed weight
    C Jako
    Seed Oil Biotechnology Group, National Research Council of Canada, Plant Biotechnology Institute, 110 Gymnasium Place, Saskatoon, Saskatchewan S7N 0W9, Canada
    Plant Physiol 126:861-74. 2001
    ..The DGAT activity in developing seed of transgenic lines was enhanced by 10% to 70%. Thus, the current study confirms the important role of DGAT in regulating the quantity of seed triacylglycerols and the sink size in developing seeds...
  20. doi Transcriptome analysis of an oil-rich race A strain of Botryococcus braunii (BOT-88-2) by de novo assembly of pyrosequencing cDNA reads
    Masato Baba
    Graduate School of Life and Environment Sciences, University of Tsukuba, Tennoudai 1 1 1, Tsukuba, Ibaraki 305 8572, Japan
    Bioresour Technol 109:282-6. 2012
    ..The transcriptome data embraced candidate genes for majority of enzymes involved in the biosynthesis of unsaturated very long-chain fatty acids. The transcriptome dataset has been deposited in the GenBank/EMBL/DDBJ database...
  21. doi New frontiers in oilseed biotechnology: meeting the global demand for vegetable oils for food, feed, biofuel, and industrial applications
    Chaofu Lu
    Department of Plant Sciences, Plant Pathology, Montana State University, Bozeman, MT 59717, USA
    Curr Opin Biotechnol 22:252-9. 2011
    ..Alternative crop platforms and emerging technologies for metabolic engineering also hold promise for meeting global demand for vegetable oils and for enhancing nutritional, industrial, and biofuel properties of vegetable oils...
  22. doi Modulation of cytokines, resistin, and distribution of adipose tissue in C57BL/6 mice by different high-fat diets
    Mariana Catta-Preta
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Nutrition 28:212-9. 2012
    ..To investigate whether changing the lipid source induces metabolic changes and/or modulates the adipose tissue distribution in mice fed with a high-fat (HF) diet...
  23. pmc Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects
    Inger Ottestad
    Department of Health, Nutrition and Management, Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, Oslo, Norway
    PLoS ONE 7:e42550. 2012
    ..The aim of this study was to investigate the effect of fish oil supplementation on the plasma lipidomic profile in healthy subjects...
  24. doi Vitamin E tocotrienols improve insulin sensitivity through activating peroxisome proliferator-activated receptors
    Fang Fang
    Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou Science City, Guangzhou, P R China
    Mol Nutr Food Res 54:345-52. 2010
    ..These lines of evidence collectively suggested that PPARs represent a set of molecular targets of tocotrienols...
  25. pmc (n-3) fatty acids and cardiovascular health: are effects of EPA and DHA shared or complementary?
    Dariush Mozaffarian
    Division of Cardiovascular Medicine and Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
    J Nutr 142:614S-625S. 2012
    ....
  26. doi Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, placebo controlled trial
    Siegfried Kasper
    Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
    Int Clin Psychopharmacol 25:277-87. 2010
    ..Lavandula oil preparation silexan is both efficacious and safe for the relief of anxiety disorder not otherwise specified. It has a clinically meaningful anxiolytic effect and alleviates anxiety related disturbed sleep...
  27. ncbi The effect of oil components on the physicochemical properties and drug delivery of emulsions: tocol emulsion versus lipid emulsion
    Chi Feng Hung
    School of Medicine, Fu Jen Catholic University, Taipei, Taiwan
    Int J Pharm 335:193-202. 2007
    ..The mean vesicle size of the tocol emulsion remained unchanged during 30 days at 37 degrees C. The lipid emulsion and aqueous micelle system, respectively, showed 11- and 16-fold increases in vesicle size after 30 days of storage...
  28. ncbi Phenolic molecules in virgin olive oils: a survey of their sensory properties, health effects, antioxidant activity and analytical methods. An overview of the last decade
    Alessandra Bendini
    Department of Food Science, University of Bologna P zza Goidanich 60, I 47023 Cesena FC, Italy
    Molecules 12:1679-719. 2007
    ..In particular, starting from the basic studies, the results of researches developed in the last ten years will be focused...
  29. ncbi Tailoring plant lipid composition: designer oilseeds come of age
    Johnathan A Napier
    Department of Biological Chemistry, Rothamsted Research, Harpenden, Herts AL5 2JQ, UK
    Curr Opin Plant Biol 13:330-7. 2010
    ..There is also growing interest in using plant oils as a replacement for petrochemicals, either for fuel or as a chemical feedstock...
  30. ncbi Palm oil: biochemical, physiological, nutritional, hematological, and toxicological aspects: a review
    D O Edem
    Department of Chemistry and Biochemistry, University of Uyo, Uyo, Akwa Ibom State, Nigeria
    Plant Foods Hum Nutr 57:319-41. 2002
    ..Red palm oil, by virtue of its beta-carotene content, may protect against vitamin A deficiency and certain forms of cancer...
  31. ncbi Effects of sea buckthorn (Hippophaë rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats
    Jianfeng Xing
    College of Pharmacy, Xi an Medical University, 710061 Xi an, PR China
    Fitoterapia 73:644-50. 2002
    ..01). The results suggested that the CO(2)-extracted sea buckthorn seed and pulp oils have both preventive and curative effects against experimental gastric ulcers in rats...
  32. pmc Castor phospholipid:diacylglycerol acyltransferase facilitates efficient metabolism of hydroxy fatty acids in transgenic Arabidopsis
    Harrie van Erp
    Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 6340, USA
    Plant Physiol 155:683-93. 2011
    ..We show the usefulness of RcPDAT1A for engineering plants with high levels of HFAs and alleviating bottlenecks due to the production of unusual FAs in transgenic oilseeds...
  33. pmc Expression of ZmLEC1 and ZmWRI1 increases seed oil production in maize
    Bo Shen
    Pioneer Hi Bred International, Inc, A DuPont Business, Johnston, Iowa 50131 1004, USA
    Plant Physiol 153:980-7. 2010
    ..These results emphasize the importance of field testing for developing a commercial high-oil product and highlight ZmWRI1 as a promising target for increasing oil production in crops...
  34. ncbi Traceability of plant contribution in olive oil by amplified fragment length polymorphisms
    Simona Pafundo
    Division of Genetics and Environmental Biotechnology, Department of Environmental Sciences, University of Parma, Parco Area delle Scienze 11 A, 43100 Parma, Italy
    J Agric Food Chem 53:6995-7002. 2005
    ....
  35. doi Tocotrienol suppresses adipocyte differentiation and Akt phosphorylation in 3T3-L1 preadipocytes
    Harumi Uto-Kondo
    Internal Medicine 1, National Defense Medical College, Tokorozawa shi, Saitama 359 8513, Japan
    J Nutr 139:51-7. 2009
    ..Furthermore, tocotrienol could act as an antiadipogenic vitamin in the nutrient-mediated regulation of body fat through its effects on differentiation...
  36. ncbi Olive oil in parenteral nutrition
    Aleix Sala-Vila
    Institute of Human Nutrition, School of Medicine, University of Southampton, Southampton, UK
    Curr Opin Clin Nutr Metab Care 10:165-74. 2007
    ..The purpose of this review is to provide background information about the rationale for this emulsion, to collate and synthesize the literature about it, and to highlight recent studies in which it has been used...
  37. doi Daily supplementation of tocotrienol-rich fraction or alpha-tocopherol did not induce immunomodulatory changes in healthy human volunteers
    Ammu K Radhakrishnan
    Department of Pathology, International Medical University, 126, Jalan 19 155B, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
    Br J Nutr 101:810-5. 2009
    ..As these observations were made in the absence of any immunogenic challenge, we feel it would be of benefit to study if there would be any differences observed when an immunogenic challenge such as vaccination were introduced...
  38. doi Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators
    Yuji Karashima
    KU Leuven Department of Mol Cell Biology, Lab Ion Channel Research, Campus Gasthuisberg, Herestraat 49, Bus 802, B 3000, Leuven, Belgium
    Pflugers Arch 457:77-89. 2008
    ....
  39. ncbi Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species
    Eugénia Pinto
    Department of Microbiology CEQOFF, Faculty of Pharmacy, University of Porto, 4050 Porto, Portugal
    J Med Microbiol 55:1367-73. 2006
    ..The present study indicates that T. pulegioides essential oil has considerable antifungal activity, deserving further investigation for clinical applications...
  40. pmc TRPA1 acts as a cold sensor in vitro and in vivo
    Yuji Karashima
    Laboratory of Ion Channel Research, Division of Physiology, Department of Molecular Cell Biology, Campus Gasthuisberg O and N1, Katholieke Universiteit Leuven, Herestraat 49 bus 802, B 3000 Leuven, Belgium
    Proc Natl Acad Sci U S A 106:1273-8. 2009
    ..Finally, cold plate and tail-flick experiments reveal TRPA1-dependent, cold-induced nociceptive behavior in mice. We conclude that TRPA1 acts as a major sensor for noxious cold...
  41. ncbi Antinociceptive effects of Teucrium polium L total extract and essential oil in mouse writhing test
    Mohammad Abdollahi
    Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, 14155 6451, Tehran
    Pharmacol Res 48:31-5. 2003
    ..polium comparable to those of hyoscine and indomethacin and suggests a good place for it in antispasmodic therapies in human. The presence of flavonoids and sterols might be responsible for the anti-inflammatory activity of this plant...
  42. doi Plant triacylglycerols as feedstocks for the production of biofuels
    Timothy P Durrett
    Department of Plant Biology, Michigan State University, East Lansing, MI 48824, USA
    Plant J 54:593-607. 2008
    ..Given their chemical similarities, plant oils represent a logical substitute for conventional diesel, a non-renewable energy source...
  43. ncbi Red palm oil: nutritional, physiological and therapeutic roles in improving human wellbeing and quality of life
    O O Oguntibeju
    Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, South Africa
    Br J Biomed Sci 66:216-22. 2009
    ..This review provides a comprehensive overview of the nutritional, physiological and biochemical roles of red palm oil in improving wellbeing and quality of life...
  44. ncbi Association mapping of seed oil content in Brassica napus and comparison with quantitative trait loci identified from linkage mapping
    Jun Zou
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China
    Genome 53:908-16. 2010
    ..napus...
  45. doi Transcriptome analysis of an oil-rich race B strain of Botryococcus braunii (BOT-22) by de novo assembly of pyrosequencing cDNA reads
    Motohide Ioki
    Environmental Biology Division, National Institute for Environmental Studies, Onogawa 16 2, Tsukuba, Ibaraki 305 8506, Japan
    Bioresour Technol 109:292-6. 2012
    ..braunii. All transcriptome sequences have been deposited in the GenBank/EMBL/DDBJ database...
  46. doi Suppression of tumor growth by palm tocotrienols via the attenuation of angiogenesis
    Wong Weng-Yew
    Malaysian Palm Oil Board, 43000 Kajang, Selangor, Malaysia
    Nutr Cancer 61:367-73. 2009
    ..TRF significantly reduced serum vascular endothelial growth factor (VEGF) level in BALB/c mice. In conclusion, this study showed that palm tocotrienols exhibit anti-angiogenic properties that may assist in tumor regression...
  47. pmc In vitro permeation and in vivo anti-inflammatory and analgesic properties of nanoscaled emulsions containing ibuprofen for topical delivery
    Ghassan Z Abdullah
    School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia
    Int J Nanomedicine 6:387-96. 2011
    ..As a topical delivery system, a nanoscaled emulsion is considered a good carrier of several active ingredients that convey several side effects upon oral administration, such as nonsteroidal anti-inflammatory drugs (NSAIDs)...
  48. pmc Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii
    Tom D Niehaus
    University of Kentucky, Lexington, KY 40546 0312, USA
    Proc Natl Acad Sci U S A 108:12260-5. 2011
    ....
  49. doi Efficacy and safety of silexan, a new, orally administered lavender oil preparation, in subthreshold anxiety disorder - evidence from clinical trials
    Siegfried Kasper
    Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
    Wien Med Wochenschr 160:547-56. 2010
    ..4 ± 7.1 and 12.0 ± 7.2 points at week 6 and by between 11.8 ± 7.7 and 16.0 ± 8.3 points at week 10. In GAD silexan and lorazepam showed comparable HAMA total score reductions (90% CI for mean value difference: -2.3; 2.8 points)...
  50. doi Trans-18:1 and CLA isomers in rumen and duodenal digesta of bulls fed n-3 and n-6 PUFA-based diets
    Xiangzhen Shen
    Key Laboratory of Animal Physiology and Biochemistry, Nanjing Agricultural University, Nanjing, 210095, People s Republic of China
    Lipids 46:831-41. 2011
    ..The concentration of trans-16-18:1 was significantly decreased in the rumen of n-3 PUFA supplemented-fed bulls compared to n-6 PUFA supplemented-fed bulls...
  51. doi A pilot study on the DNA-protective, cytotoxic, and apoptosis-inducing properties of olive-leaf extracts
    Jaouad Anter
    Department of Genetics, University of Cordoba, Campus Rabanales, 14071 Cordoba, Spain
    Mutat Res 723:165-70. 2011
    ..These results could help explain the mechanism of action that underlies the beneficial effect of OLE, proposed as a nutraceutical in the prevention of human cancer...
  52. doi The identification and mapping of candidate genes and QTL involved in the fatty acid desaturation pathway in Brassica napus
    A M Smooker
    Department of Crop Genetics, John Innes Centre, Norwich Research Park, Colney, Norwich, NR4 7UH, UK
    Theor Appl Genet 122:1075-90. 2011
    ..napus that might be useful for modulating the content or extent of desaturation of polyunsaturated fatty acids, only one of which coincides with the anticipated position of a candidate gene, an orthologue of FAD2...
  53. doi Diet × genotype interactions in hepatic cholesterol and lipoprotein metabolism in Atlantic salmon (Salmo salar) in response to replacement of dietary fish oil with vegetable oil
    Sofia Morais
    Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, Scotland, UK
    Br J Nutr 106:1457-69. 2011
    ..Finally, the presence of three different transcripts for LPL, with differential patterns of nutritional regulation, was demonstrated...
  54. doi Cytotoxic and apoptotic activity of essential oil from Ocimumviride towards COLO 205 cells
    Madhunika Sharma
    Oncology Group, Pharmacology Division, Indian Institute of Integrative Medicine, Jammu J and K 180016, India
    Food Chem Toxicol 48:336-44. 2010
    ..Our results reveal that EO has apoptosis inducing effect against COLO 205 cells in vitro and is a promising candidate for further anti-cancer study...
  55. pmc Duplicate maize Wrinkled1 transcription factors activate target genes involved in seed oil biosynthesis
    Benjamin Pouvreau
    Universite de Lyon, Ecole Normale Superieure de Lyon, Universite Lyon 1, IFR128 Biosciences Lyon Gerland, Unité Reproduction et Développement des Plantes, F 69364 Lyon, France
    Plant Physiol 156:674-86. 2011
    ..Interestingly, the higher seed oil content in ZmWri1a overexpression lines is not accompanied by a reduction in starch, thus opening possibilities for the use of the transgenic maize lines in breeding programs...
  56. doi Cofactome analyses reveal enhanced flux of carbon into oil for potential biofuel production
    Daniel M Hayden
    Department of Plant Biology, University of California Davis, Davis, CA, USA
    Plant J 67:1018-28. 2011
    ..These data highlight a close association between cofactomes and carbon partitioning, thereby providing a biotechnological target for conversion of starch to oil...
  57. ncbi Antibacterial effect of some essential oils administered alone or in combination with Norfloxacin
    Antonio Rosato
    Department Farmaco Chimico, Section of Microbiology, Faculty of Pharmacy, University of Bari, Via Orabona 4, Bari, Italy
    Phytomedicine 14:727-32. 2007
    ....
  58. doi Development of anaerobic digestion methods for palm oil mill effluent (POME) treatment
    P E Poh
    School of Chemical and Environmental Engineering, Faculty of Engineering, The University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor, Malaysia
    Bioresour Technol 100:1-9. 2009
    ..This review aims to discuss the various anaerobic treatments of POME and factors that influence the operation of anaerobic treatment. The POME treatment at both mesophilic and thermophilic temperature ranges are also analyzed...
  59. doi Unusually large oilbodies are highly correlated with lower oil content in Brassica napus
    Zhiyong Hu
    Key Laboratory for Biological Sciences of Oil Crops, Ministry of Agriculture, Oil Crops Research Institute, Chinese Academy of Agriculture Sciences, Wuhan, People s Republic of China
    Plant Cell Rep 28:541-9. 2009
    ..The low accumulation of oleosins results in the forming of unusually large oilbodies in LO cultivars...
  60. pmc Effects of the total replacement of fish-based diet with plant-based diet on the hepatic transcriptome of two European sea bass (Dicentrarchus labrax) half-sibfamilies showing different growth rates with the plant-based diet
    Florian Geay
    IFREMER, UMR 1067, Departement Physiologie Fonctionnelle des Organismes Marins, Technopole Brest Iroise, BP 70, 29280 Plouzane, France
    BMC Genomics 12:522. 2011
    ..The main objective of the present study was to analyse the effects of a plant-based diet on the hepatic transcriptome of European sea bass (Dicentrarchus labrax)...
  61. ncbi Insecticidal properties of essential plant oils against the mosquito Culex pipiens molestus (Diptera: Culicidae)
    Abdallah F Traboulsi
    Faculty of Agricultural Sciences, Lebanese University, Beirut, Lebanon
    Pest Manag Sci 58:491-5. 2002
    ..Thymol, carvacrol, (1R)-(+)-alpha-pinene and (1S)-(-)-alpha-pinene were the most toxic (LC50 = 36-49 mg litre-1), while menthone, 1,8-cineole, linalool and terpineol (LC50 = 156-194 mg litre-1) were less toxic...
  62. doi Safety and efficacy of a lipid emulsion containing a mixture of soybean oil, medium-chain triglycerides, olive oil, and fish oil: a randomised, double-blind clinical trial in premature infants requiring parenteral nutrition
    Erika Tomsits
    2nd Department of Paediatrics, Semmelweis University, Budapest, Hungary
    J Pediatr Gastroenterol Nutr 51:514-21. 2010
    ....
  63. pmc Oleic acid content is responsible for the reduction in blood pressure induced by olive oil
    S Terés
    Laboratory of Molecular Cell Biomedicine, Department of Biology, Institut Universitari d Investigacions en Ciències de la Salut, University of the Balearic Islands, Carretera de Valldemossa Km 7 5, E 07122 Palma de Mallorca, Spain
    Proc Natl Acad Sci U S A 105:13811-6. 2008
    ..Similarly, soybean oil (with low OA content) did not reduce BP. This study demonstrates that olive oil induces its hypotensive effects through the action of OA...
  64. doi The nutritional background of the host alters the disease course in a fish-myxosporean system
    Itziar Estensoro
    Fish Pathology Group, Department of Marine Species Biology, Culture and Pathology, Instituto de Acuicultura de Torre de la Sal CSIC, 12595 Ribera de Cabanes, Castellon, Spain
    Vet Parasitol 175:141-50. 2011
    ..Parasite intensity of infection was negatively correlated with growth parameters and haematocrit in both groups, and with complement, lysozyme and hepatic total glutathione in 66VO fish...
  65. ncbi Traceability markers to the botanical origin in olive oils
    Cristina Montealegre
    Department of Analytical Chemistry, Faculty of Chemistry, University of Alcala, Ctra Madrid Barcelona Km 33 600, 28871 Alcala de Henares, Madrid, Spain
    J Agric Food Chem 58:28-38. 2010
    ..They have been considered as traceability markers to the botanical origin and classified, in this work, as compositional and genetical markers...
  66. ncbi Parenteral lipid emulsions based on olive oil compared with soybean oil in preterm (<28 weeks' gestation) neonates: a randomised controlled trial
    Girish C Deshpande
    Department of Neonatal Paediatrics, King Edward Memorial Hospital for Women, Perth, Australia
    J Pediatr Gastroenterol Nutr 49:619-25. 2009
    ..New olive oil-based (OL) lipid emulsions (olive:soy oil = 4:1) have lower polyunsaturated fatty acid (PUFA) (20% vs 60%) and higher vitamin E content (an antioxidant) compared with traditional soybean oil (SO) emulsions...
  67. ncbi Effect of fish and oil nature on frying process and nutritional product quality
    Diana Ansorena
    Dept of Nutrition and Food Sciences, Physiology and Toxicology, Faculty of Pharmacy, Univ of Navarra, Irunlarrea s n, 31008 Pamplona, Spain
    J Food Sci 75:H62-7. 2010
    ..The use of extra virgin olive oil was efficient to avoid a significant increase of the lipid oxidation intensity during frying in cod but not in salmon...
  68. ncbi HDL-related mechanisms of olive oil protection in cardiovascular disease
    José M Lou-Bonafonte
    Departamento de Farmacología y Fisiología, Facultad de Ciencias de la Salud y del Deporte, Universidad de Zaragoza, Zaragoza, Spain
    Curr Vasc Pharmacol 10:392-409. 2012
    ..Further studies in this field in humans and in animal models are warranted due to the complexity of HDL particles...
  69. ncbi Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder
    B Uehleke
    Charité Universitaetsmedizin Berlin and Immanuel Krankenhaus, Berlin, Germany
    Phytomedicine 19:665-71. 2012
    ..The results in this trial justify to further investigate Silexan in disorders with accompanying restlessness caused by sub-threshold anxiety. Adverse reactions, predominantly gastrointestinal complaints, were judged as mild or moderate...
  70. pmc Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice
    Lolita M Forrest
    Department of Pathology Section on Lipid Sciences, Wake Forest School of Medicine, Winston Salem, NC 27157, United States
    Atherosclerosis 220:118-21. 2012
    ..Echium oil contains stearidonic acid (SDA; 18:4, n-3), which is metabolized to EPA in humans and mice, resulting in decreased plasma triglycerides...
  71. pmc Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells
    Mahmoud M Suhail
    Al Afia Medical Complex, Salalah, Sultanate of Oman
    BMC Complement Altern Med 11:129. 2011
    ....
  72. doi A new intravenous fat emulsion containing soybean oil, medium-chain triglycerides, olive oil, and fish oil: a single-center, double-blind randomized study on efficacy and safety in pediatric patients receiving home parenteral nutrition
    Olivier Goulet
    Department of Pediatric Gastroenterology, Hepatology and Nutrition, Hopital des Enfants Malades, University of Paris 5, René Descartes, France
    JPEN J Parenter Enteral Nutr 34:485-95. 2010
    ..The aim was to assess the efficacy and safety of this new ILE in pediatric patients receiving home parenteral nutrition (HPN) compared with soybean oil emulsion (SOE)...
  73. pmc Palm oil-derived natural vitamin E alpha-tocotrienol in brain health and disease
    Chandan K Sen
    Department of Surgery, The Ohio State University Medical Center, Columbus, Ohio, USA
    J Am Coll Nutr 29:314S-323S. 2010
    ..Despite such therapeutic potential, the scientific literature on tocotrienols accounts for roughly 1% of the total literature on vitamin E, thus warranting further investment and investigation...
  74. doi Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat
    Hong Wei
    Institute of Biomedicine Physiology, University of Helsinki, Biomedicum Helsinki, POB 63, 00014 Helsinki, Finland
    Neuropharmacology 58:578-84. 2010
    ....
  75. doi Campylobacter and Arcobacter species sensitivity to commercial orange oil fractions
    Ramakrishna Nannapaneni
    Center for Food Safety IFSE and Department of Food Science, University of Arkansas, Fayetteville, AR 72704, USA
    Int J Food Microbiol 129:43-9. 2009
    ..The study demonstrated the potential of the selected commercial orange oil fractions to serve as natural antimicrobials against C. jejuni, C. coli, and Arcobacter spp...
  76. doi Molecular mapping of Arabidopsis thaliana lipid-related orthologous genes in Brassica napus
    Jianyi Zhao
    Institute of Crop and Nuclear Technology Utilization, Zhejiang Academy of Agricultural Sciences, Hangzhou, China
    Theor Appl Genet 124:407-21. 2012
    ..The information obtained from this study demonstrates the potential role of the suggested candidate genes in rapeseed kernel oil accumulation...
  77. ncbi Feeding co-extruded flaxseed to pigs: effects of duration and feeding level on growth performance and backfat fatty acid composition of grower-finisher pigs
    M Juarez
    Agriculture and Agri Food Canada, Lacombe Research Centre, 6000 C and E Trail, Lacombe, Alberta, Canada
    Meat Sci 84:578-84. 2010
    ....
  78. doi Nutritional benefit of olive oil: the biological effects of hydroxytyrosol and its arylating quinone adducts
    David G Cornwell
    Department of Molecular and Cellular Biochemistry, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA
    J Agric Food Chem 56:8774-86. 2008
    ....
  79. ncbi Prevention of Candida albicans biofilm by plant oils
    Vishnu Agarwal
    Molecular Microbiology Laboratory, Department of Biotechnology, Indian Institute of Technology, Roorkee, Uttarakhand 247667, India
    Mycopathologia 165:13-9. 2008
    The inhibitory effect of 30 plant oils was evaluated against biofilm forming Candida albicans strain (CA I) isolated from clinical samples, which was sensitive to 4 microg/ml of fluconazole, used as a positive control...
  80. doi An Arabidopsis family of six acyl-CoA-binding proteins has three cytosolic members
    Shi Xiao
    School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong, China
    Plant Physiol Biochem 47:479-84. 2009
    ....
  81. ncbi Chemosystematic value of the essential oil composition of Thuja species cultivated in Poland-antimicrobial activity
    Dimitroula Tsiri
    Division of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Athens 15771, Greece
    Molecules 14:4707-15. 2009
    ..The oils of the two T. plicata species exhibited significant antimicrobial activity, while the mixture of alpha- and beta-thujone showed very strong activity as well...
  82. ncbi Effects of dietary palmitoleic acid on plasma lipoprotein profile and aortic cholesterol accumulation are similar to those of other unsaturated fatty acids in the F1B golden Syrian hamster
    Nirupa R Matthan
    Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    J Nutr 139:215-21. 2009
    ..These data suggest that an oil relatively high in palmitoleic acid does not adversely affect plasma lipoprotein profiles or aortic cholesterol accumulation and was similar to other unsaturated fatty acid-rich oils...
  83. doi Micronutrient-enriched rapeseed oils improve the brain oxidant/antioxidant system in rats fed a high-fat diet
    Serafina Salvati
    Department of Public Veterinary Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy
    J Agric Food Chem 59:4483-8. 2011
    ..These results indicate that a regular intake of optimized rapeseed oils can prevent oxidative stress, providing evidence that optimized rapeseed oils could be a functional food with potentially important neuroprotective properties...
  84. doi Olive oil and cardiovascular health
    Maria Isabel Covas
    Cardiovascular Risk and Nutrition Research Group, Institut Municipal d Investigacio Medica IMIM, CIBER de Fisiopatologia de la Obesidad y Nutricion CIBEROBN, Barcelona, Spain
    J Cardiovasc Pharmacol 54:477-82. 2009
    ....
  85. pmc Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar)
    Michael J Leaver
    Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, UK
    BMC Genomics 9:299. 2008
    ..FO was replaced with VO, added to diets as rapeseed (RO), soybean (SO) or linseed (LO) oils...
  86. pmc Effect of ω-3 and ω-9 fatty acid rich oils on lipoxygenases and cyclooxygenases enzymes and on the growth of a mammary adenocarcinoma model
    Andrea Comba
    Instituto de Biologia Celular, Facultad de Ciencias Medicas, Universidad Nacional de Cordoba, Argentina
    Lipids Health Dis 9:112. 2010
    ..We studied the effect of two diets enriched in 6% Walnut and Peanut oils that are rich in ω-3 and ω9 PUFAs respectively on a murine mammary gland adenocarcinoma as compared with the control (C) that received commercial diet...
  87. ncbi Oxidative stability measurement of high-stability oils by pressure differential scanning calorimeter (PDSC)
    Dharma R Kodali
    Cargill Inc, P O Box 5699, Minneapolis, Minnesota 55440 5699, USA
    J Agric Food Chem 53:7649-53. 2005
    ..The development of this method into an approved method will benefit the fats/oils and food industry...
  88. ncbi Effect of Nigella sativa on glucose concentration, lipid peroxidation, anti-oxidant defence system and liver damage in experimentally-induced diabetic rabbits
    I Meral
    Department of Physiology, Veterinary Medicine, Yuzuncu Yil University, Van, Turkey
    J Vet Med A Physiol Pathol Clin Med 48:593-9. 2001
    ..It was concluded that N. sativa might be used in diabetic patients to prevent lipid peroxidation, increase anti-oxidant defence system activity and also prevent liver damage...
  89. pmc Olive oil, diet and colorectal cancer: an ecological study and a hypothesis
    M Stoneham
    Unit of Health Care Epidemiology, Department of Public Health, Oxford University, Institute of Health Sciences, Oxford
    J Epidemiol Community Health 54:756-60. 2000
    ..The purpose of this study was to compare national levels of dietary factors, with particular reference to olive oil, with national differences in CRC incidence...
  90. ncbi Fatty acid composition of lipids in sea buckthorn (Hippophaë rhamnoides L.) berries of different origins
    B Yang
    Department of Biochemistry and Food Chemistry, University of Turku, FIN 20014 Turku, Finland
    J Agric Food Chem 49:1939-47. 2001
    ..In the oil of whole berries, the proportion of palmitoleic acid correlated negatively with the proportions of linoleic and alpha-linolenic acids...
  91. ncbi Kinetic profile of the cellular lipid composition in an oleaginous Yarrowia lipolytica capable of producing a cocoa-butter substitute from industrial fats
    S Papanikolaou
    , CNRS-ENSIC/ENSAIA UPR 6811,
    Antonie Van Leeuwenhoek 80:215-24. 2001
    ..This permitted the synthesis of interesting lipid profiles with high percentages of stearic acid and non-negligible percentages of palmitic and oleic acid, with a composition resembling that of cocoa-butter...
  92. ncbi Heated palm oil causes rise in blood pressure and cardiac changes in heart muscle in experimental rats
    Xin Fang Leong
    Department of Pharmacology, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia
    Arch Med Res 39:567-72. 2008
    ..The purpose of the study was to observe the effect of heated palm oil on blood pressure and observe the cardiac histological changes in rats...
  93. ncbi Acaricidal activity of constituents identified in Foeniculum vulgare fruit oil against Dermatophagoides spp. (Acari: Pyroglyphidae)
    Hoi Seon Lee
    Faculty of Biotechnology and Research Center for Industrial Development of Biofood Materials, Chonbuk National University, Chonju 561 756, Korea
    J Agric Food Chem 52:2887-9. 2004
    ..Fenchone was 20.3 times more abundant in the oil than p-anisaldehyde. (+)-Fenchone and p-anisaldehyde merit further study as potential house dust mite control agents or as lead compounds...
  94. ncbi Modeling lipid accumulation and degradation in Yarrowia lipolytica cultivated on industrial fats
    Seraphim Papanikolaou
    Laboratoire des Sciences du Génie Chimique Centre Nationale de la Recherche Scientifique, Ecole Nationale superieure des Industries Chimiques, 13, rue du Bois de la Champelle, 54500, Vandoeuvre les Nancy, France
    Curr Microbiol 46:398-402. 2003
    ..However, the fat-free biomass yield on storage lipids (g of fat-free biomass formed per g of storage lipids consumed) was higher than the one on the substrate (g of fat-free biomass formed per g of medium fat consumed)...
  95. ncbi Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters
    K M Fararh
    Department of Physiology and Pathogenetic Veterinary Sciences, The United Graduate School, Gifu University, 1 1 Yanagido, 501 1193 Gifu, Japan
    Res Vet Sci 77:123-9. 2004
    ..sativa oil is mediated through stimulation of macrophage phagocytic activity either directly or via activation of lymphocytes...
  96. pmc Metabolic control analysis is helpful for informed genetic manipulation of oilseed rape (Brassica napus) to increase seed oil content
    Randall J Weselake
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada T6G 2P5
    J Exp Bot 59:3543-9. 2008
    ..The most effective lines had a seed oil increase of 14%. Moreover, overexpression of DGAT1 under drought conditions reduced this environmental penalty on seed oil content...
  97. ncbi Proteomic analysis of early germs with high-oil and normal inbred lines in maize
    Zhanji Liu
    National Maize Improvement Center of China, China Agricultural University, Beijing 100094, China
    Mol Biol Rep 36:813-21. 2009
    ..This study represents the first proteomic analysis of high-oil maize and contributes to a better understanding of the molecular basis of oil accumulation in high-oil maize...
  98. doi Cloning and characterization of an acyl-CoA-dependent diacylglycerol acyltransferase 1 (DGAT1) gene from Tropaeolum majus, and a study of the functional motifs of the DGAT protein using site-directed mutagenesis to modify enzyme activity and oil content
    Jingyu Xu
    National Research Council of Canada, Plant Biotechnology Institute, 110 Gymnasium Place, Saskatoon, Canada
    Plant Biotechnol J 6:799-818. 2008
    ..Thus, alteration of this putative serine/threonine protein kinase site can be exploited to enhance DGAT1 activity, and expression of mutated DGAT1 can be used to enhance oil content...
  99. ncbi Effect of variation of trans-fatty acid in lactating rats' diet on lipoprotein lipase activity in mammary gland, liver, and adipose tissue
    Renata Pereira Assumpção
    Instituto de Nutricao Josue de Castro, Universidade Federal do Rio de Janeiro, Brazil
    Nutrition 20:806-11. 2004
    ..We investigated the effects of different dietary contents of trans-fatty acid (TFA) on LPL activity in maternal tissues and fatty acid composition in milk...
  100. doi High-value oils from plants
    John M Dyer
    United States Department of Agriculture, Agricultural Research Service, US Arid Land Agricultural Research Center, Maricopa, AZ 85238, USA
    Plant J 54:640-55. 2008
    ..b>Plant oils can provide renewable sources of high-value fatty acids for both the chemical and health-related industries...
  101. doi Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men
    Yolanda Jimenez-Gomez
    The Lipids and Arteriosclerosis Unit, Reina Sofia University Hospital, University of Cordoba, CIBER de Fisiopatologia de la Obesidad y Nutricion CIBEROBN, Avenida Menendez Pidal s n, 14004 Cordoba, Spain
    Atherosclerosis 204:e70-6. 2009
    ..Inflammation is crucial in all stages of atherosclerosis, and few studies have investigated the effect of dietary fat on markers of inflammation related to this disease during the postprandial period...

Research Grants114 found, 100 shown here

  1. UKY DENTAL COBRE: ORAL INFECTIONS: DIETARY REGULATION OF INFLAMMATORY RESPONSES
    Dolph Dawson; Fiscal Year: 2004
    ..cold-water fish such as salmon, cod, tuna, or mackerel) or plant oils (eg. flax, linseed), can contribute to the prevention and treatment of disease...
  2. DIETARY LIPIDS AND EXPERIMENTAL IGA NEPHROPATHY
    James Pestka; Fiscal Year: 2001
    ..will be to understand specific mechanisms by which dietary polyunsaturated fatty acids (n-3 PUFA) in marine and plant oils impair development and progression of immunoglobulin A nephropathy (IgAN)...
  3. DIETARY LIPIDS AND EXPERIMENTAL IGA NEPHROPATHY
    James Pestka; Fiscal Year: 2004
    ..will be to understand specific mechanisms by which dietary polyunsaturated fatty acids (n-3 PUFA) in marine and plant oils impair development and progression of immunoglobulin A nephropathy (IgAN)...
  4. DIETARY LIPIDS AND EXPERIMENTAL IGA NEPHROPATHY
    James Pestka; Fiscal Year: 2002
    ..will be to understand specific mechanisms by which dietary polyunsaturated fatty acids (n-3 PUFA) in marine and plant oils impair development and progression of immunoglobulin A nephropathy (IgAN)...
  5. DIETARY LIPIDS AND EXPERIMENTAL IGA NEPHROPATHY
    James Pestka; Fiscal Year: 2003
    ..will be to understand specific mechanisms by which dietary polyunsaturated fatty acids (n-3 PUFA) in marine and plant oils impair development and progression of immunoglobulin A nephropathy (IgAN)...
  6. ROLE OF IRON OXO CLUSTERS IN FATTY ACID DESATURATION
    Brian Fox; Fiscal Year: 2000
    ..The proposed studies will also reveal the molecular details of reaction with non-natural trans fatty acids, which are increasingly found in human diet from the consumption of partially hydrogenated plant oils.
  7. ROLE OF IRON OXO CLUSTERS IN FATTY ACID DESATURATION
    Brian Fox; Fiscal Year: 2002
    ..The proposed studies will also reveal the molecular details of reaction with non-natural trans fatty acids, which are increasingly found in human diet from the consumption of partially hydrogenated plant oils.
  8. ROLE OF IRON OXO CLUSTERS IN FATTY ACID DESATURATION
    Brian Fox; Fiscal Year: 2001
    ..The proposed studies will also reveal the molecular details of reaction with non-natural trans fatty acids, which are increasingly found in human diet from the consumption of partially hydrogenated plant oils.
  9. ROLE OF IRON OXO CLUSTERS IN FATTY ACID DESATURATION
    Brian Fox; Fiscal Year: 2003
    ..The proposed studies will also reveal the molecular details of reaction with non-natural trans fatty acids, which are increasingly found in human diet from the consumption of partially hydrogenated plant oils.
  10. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2008
    ....
  11. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2007
    ....
  12. Fatty Acids and Cardiovascular Health
    Dariush Mozaffarian; Fiscal Year: 2007
    ..End of Abstract) [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  13. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  14. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2007
    ....
  15. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2006
    ....
  16. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2010
    ....
  17. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  18. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  19. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2008
    ....
  20. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2010
    ....
  21. Mercury, Selenium and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  22. Prolactin Regulation of Trigeminal Nociceptors
    Armen N Akopian; Fiscal Year: 2010
    ....
  23. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2010
    ..This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway. ..
  24. Impact of feeding on brain response to food stimuli in lean and obese subjects
    Marie Pierre St Onge; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  25. Metabolism and Pharmacogenetics in MDMA-Induced Toxicity
    Rafael de la Torre; Fiscal Year: 2006
    ..A study will compare MDMA toxicity when co-adminsitered with the MRP1 inhibitor probenecid. ..
  26. Design and Synthesis of HIV-1 Protease Inhibitors
    AMOS SMITH; Fiscal Year: 2003
    ....
  27. Prolactin Regulation of Trigeminal Nociceptors
    ARMEN AKOPIAN; Fiscal Year: 2007
    ....
  28. INTERACTIONS OF TRPV1 AND TRPA1 AND INFLAMMATORY PAIN
    Armen N Akopian; Fiscal Year: 2010
    ..abstract_text> ..
  29. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    AMOS SMITH; Fiscal Year: 2003
    ..Thus, as we develop an approach to each target structure, we will also prepare model compounds designed to permit the elucidation of structure-activity relationships. ..
  30. ANTICANCER AGENTS--STRUCTURE AND SYNTHESIS
    AMOS SMITH; Fiscal Year: 2002
    ..The design of new and possibly more effective agents should then be feasible. ..
  31. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2008
    ..This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway. ..
  32. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2009
    ..This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway. ..
  33. SYNTHESIS OF SPONGISTATIN ANTITUMOR AGENTS
    AMOS SMITH; Fiscal Year: 2004
    ..abstract_text> ..
  34. Prolactin Regulation of Trigeminal Nociceptors
    ARMEN AKOPIAN; Fiscal Year: 2008
    ....
  35. Metabolism and Pharmacogenetics in MDMA-Induced Toxicity
    Rafael de la Torre; Fiscal Year: 2008
    ..A study will compare MDMA toxicity when co-adminsitered with the MRP1 inhibitor probenecid. ..
  36. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    AMOS SMITH; Fiscal Year: 2009
    ..Our experience with discodermolide gives us great confidence in this area. ..
  37. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    Amos B Smith; Fiscal Year: 2010
    ..Our experience with discodermolide gives us great confidence in this area. ..
  38. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2009
    ..This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway. ..
  39. Anticancer Agents: Structure and Synthesis
    Amos B Smith; Fiscal Year: 2010
    ..To this end, new synthetic chemistry will be developed that will have utility not only for this program, but also be of general value to the academic and pharmaceutical communities engaged in Cancer Biology. ..
  40. ANTICANCER AGENTS--STRUCTURE AND SYNTHESIS
    AMOS SMITH; Fiscal Year: 2006
    ..Thus, as we develop an approach to each target structure, we will also prepare model compounds designed to permit the elucidation of structure-activity relationships. ..
  41. SYNTHESIS OF SPONGISTATIN ANTITUMOR AGENTS
    AMOS SMITH; Fiscal Year: 2005
    ..abstract_text> ..
  42. Mechanisms of Nociceptive Neuronal Plasticity
    ARMEN AKOPIAN; Fiscal Year: 2004
    ..abstract_text> ..
  43. SYNTHESIS OF SPONGISTATIN ANTITUMOR AGENTS
    AMOS SMITH; Fiscal Year: 2002
    ..We believe that this philosophy of "unified" synthetic strategies" will be amply demonstrated in this proposal. ..
  44. ANTICANCER AGENTS--STRUCTURE AND SYNTHESIS
    AMOS SMITH; Fiscal Year: 2001
    ..The design of new and possibly more effective agents should then be feasible. ..
  45. Design and Synthesis of HIV-1 Protease Inhibitors
    AMOS SMITH; Fiscal Year: 2001
    ....
  46. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    AMOS SMITH; Fiscal Year: 1991
    ..FK506 is therefore an important target for total synthesis, not only for its intrinsic synthetic challenge, but also due to its extrinsic worth to the field of medicine...
  47. SYNTHESIS OF SPONGISTATIN ANTITUMOR AGENTS
    AMOS SMITH; Fiscal Year: 2000
    ..We believe that this philosophy of "unified" synthetic strategies" will be amply demonstrated in this proposal. ..
  48. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    AMOS SMITH; Fiscal Year: 2000
    ..This philosophy of "unified synthetic strategies" will be further developed in this proposal. ..
  49. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    AMOS SMITH; Fiscal Year: 1992
    ..We believe that this philosophy of "unified synthetic strategies" will be further developed by this proposal...
  50. SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS
    AMOS SMITH; Fiscal Year: 2001
    ..This philosophy of "unified synthetic strategies" will be further developed in this proposal. ..
  51. Prolactin Regulation of Trigeminal Nociceptors
    ARMEN AKOPIAN; Fiscal Year: 2009
    ....
  52. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 1992
    ..The computer program CONSAAM will be used for biokinetic modeling of fatty acid transport and transformation as components of specific lipid classes in lipoproteins and plasma borne cell types...
  53. Microchip to Detect Influenza Infection and Type in Nasopharyngeal Swabs
    Catherine Klapperich; Fiscal Year: 2008
    ....
  54. BIOCHEMICAL CHARACTERIZATION OF PPAR
    JOHN VANDEN HEUVEL; Fiscal Year: 2007
    ..Taken together the proposed studies will greatly enhance our knowledge of PPARalpha's mechanism of action and hence our understanding of an important class of carcinogen. ..
  55. BIOCHEMICAL CHARACTERIZATION OF PPAR
    JOHN VANDEN HEUVEL; Fiscal Year: 2000
    ..Taken together the proposed studies will greatly increase our knowledge of PPARalpha's mechanism of action and hence our understanding of an important class of chemical carcinogens. ..
  56. Metabolism and Pharmacogenetics in MDMA-Induced Toxicity
    Rafael de la Torre; Fiscal Year: 2007
    ..A study will compare MDMA toxicity when co-adminsitered with the MRP1 inhibitor probenecid. ..
  57. MECHANISMS OF NGF-INDUCED COGNITIVE IMPROVEMENT IN AGING
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2000
    ..Finally, this work will evaluate the efficacy of a novel means of delivering NGF to the brain which has clear advantages over conventional techniques in terms of potential clinical application. ..
  58. AGED FOREBRAIN CHOLINERGIC NEURONS--ESTROGEN AND NGF
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2001
    ..of wildtype cholinergic neurons succumb to the same phenotype loss when grafted into a TS65DN host? And 4) Can treatment with NGF and/or estrogen alleviate cognitive alterations and cholinergic phenotype loss in the Ts65Dn mouse? ..
  59. MODULATION OF INTESTINAL OBESITY SIGNALS
    Patrick Tso; Fiscal Year: 2001
    ..In addition, the apo A-IV knockout and transgenic animals will be used to determine if there is interaction between the lymph glucose and lymph apo A-IV signals. ..
  60. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2003
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  61. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2001
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  62. MODULATION OF INTESTINAL OBESITY SIGNALS
    Patrick Tso; Fiscal Year: 2000
    ..In addition, the apo A-IV knockout and transgenic animals will be used to determine if there is interaction between the lymph glucose and lymph apo A-IV signals. ..
  63. GENE-DIET INTERACTIONS AND HEART DISEASE
    HANNAI CAMPOS; Fiscal Year: 2000
    ..This study will provide the most complete data set to study numerous hypotheses relating genes, diet, and CHD, and could lead to specific targeted interventions for reducing the development of CHD. ..
  64. INTERACTIONS OF TRPV1 AND TRPA1 AND INFLAMMATORY PAIN
    ARMEN AKOPIAN; Fiscal Year: 2009
    ..abstract_text> ..
  65. CORONARY MICROVASCULAR RESPONSES TO HUMORAL SUBSTANCES
    Kathryn Lamping; Fiscal Year: 1993
    ....
  66. Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis
    Mahmoud Elsohly; Fiscal Year: 2006
    ..This proposal addresses a major public health problem, namely contact allergic dermatitis and promises the development of an effective agent to address this problem. [unreadable] [unreadable]..
  67. BIOCHEMICAL CHARACTERIZATION OF PPAR
    JOHN VANDEN HEUVEL; Fiscal Year: 2003
    ..Taken together the proposed studies will greatly increase our knowledge of PPARalpha's mechanism of action and hence our understanding of an important class of chemical carcinogens. ..
  68. The Wake Forest and Harvard Center for Botanical Lipids
    FLOYD CHILTON; Fiscal Year: 2007
    ..These interactive and synergistic studies have a strong scientific basis and are likely to provide new understanding regarding the treatment of chronic inflammatory diseases such as atherosclerosis and asthma with botanical oils...
  69. An animal model for age-related degeneration
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2008
    ..The overall purpose of these studies is to investigate endogenous defense mechanisms as well as the degenerative process in itself, to explore if early intervention strategies can be employed. ..
  70. Microchip to Detect Influenza Infection and Type in Nasopharyngeal Swabs
    Catherine M Klapperich; Fiscal Year: 2010
    ....
  71. Alzhelmer's Disease Drug Development Program
    AMOS SMITH; Fiscal Year: 2008
    ....
  72. Vitamin E Neuroprotection: Novel Molecular Mechanisms
    Chandan K Sen; Fiscal Year: 2010
    ..NARRATIVE The project seeks to establish 1-tocotrienol, a natural vitamin E poorly present in American diet, as a dietary ingredient effective against stroke-related damage to the neural tissue. ..
  73. Pilot-Scale Libraries for High-throughput Screening
    AMOS SMITH; Fiscal Year: 2008
    ....
  74. Redox Control of Wound Healing
    Chandan Sen; Fiscal Year: 2005
    ..Determine the significance of NADPH oxidases at the wound site; and Aim 3. Characterize the redox-sensitive mechanisms that regulate wound angiogenesis. ..
  75. Vitamin E Neuroprotection: Novel Molecular Mechanisms
    Chandan Sen; Fiscal Year: 2005
    ..This study will lay the foundation for a safe and efficient approach to prevent death and secure normal functioning of neurons under challenging conditions. ..
  76. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2004
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  77. Anti-Trypanosomal Agents from a Neotropical Cloudforest
    WILLIAM SETZER; Fiscal Year: 2004
    ..The long-term benefit of this research project is the development of new medicines to treat patients with Chagas disease. ..
  78. Mechanisms of neurotrophin-improved cognition in aging
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2003
    ..abstract_text> ..
  79. AGED FOREBRAIN CHOLINERGIC NEURONS--ESTROGEN AND NGF
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2003
    ..of wildtype cholinergic neurons succumb to the same phenotype loss when grafted into a TS65DN host? And 4) Can treatment with NGF and/or estrogen alleviate cognitive alterations and cholinergic phenotype loss in the Ts65Dn mouse? ..
  80. MECHANISMS OF NGF-INDUCED COGNITIVE IMPROVEMENT IN AGING
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2001
    ..Finally, this work will evaluate the efficacy of a novel means of delivering NGF to the brain which has clear advantages over conventional techniques in terms of potential clinical application. ..
  81. MECHANISMS OF NGF-INDUCED COGNITIVE IMPROVEMENT IN AGING
    ANN CHARLOTTE GRANHOLM BENTLEY; Fiscal Year: 2001
    ..Finally, this work will evaluate the efficacy of a novel means of delivering NGF to the brain which has clear advantages over conventional techniques in terms of potential clinical application. ..
  82. Conference--Wound Healing : O2 and Emerging Therapeutics
    Chandan Sen; Fiscal Year: 2002
    ..Oxygen Sensing Oxidant Signaling & Redox Regulated Gene Expression Oxygen Therapy of Wounds Potential and Limitations of Clinical Gene Therapy for Wound Care Wound Angiogenesis Inflammation and Bacterial Control Clinical Care ..
  83. Vitamin E Neuroprotection: Novel Molecular Mechanisms
    Chandan Sen; Fiscal Year: 2002
    ..This study will lay the foundation for a safe and efficient approach to prevent death and secure normal functioning of neurons under challenging conditions. ..