unsaturated dietary fats

Summary

Summary: Unsaturated fats or oils used in foods or as a food.

Top Publications

  1. ncbi Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions
    C N Serhan
    Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Physiol Pharmacol 51:643-54. 2000
  2. ncbi Dietary factors and growth and metabolism in experimental tumors
    Leonard A Sauer
    Bassett Research Institute, Cooperstown, NY 13326, USA
    J Nutr Biochem 18:637-49. 2007
  3. ncbi Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP Diet and Health Study cohort
    Anne C M Thiebaut
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Executive Plaza South Rm 3033, Bethesda, MD 20892, USA
    J Natl Cancer Inst 99:451-62. 2007
  4. ncbi Effect of dietary alpha-linolenic acid on the activity and gene expression of hepatic fatty acid oxidation enzymes
    T Ide
    Laboratory of Nutrition Biochemistry, National Food Research Institute, Ministry of Agriculture, Forestry and Fisheries, Tsukuba, Japan
    Biofactors 13:9-14. 2000
  5. ncbi Hypertension is related to the degradation of dietary frying oils
    Federico Soriguer
    Servicio de Endocrinologia y Nutricion, Hospital Civil Hospital Universitario Carlos Haya, Plaza del Hospital Civil, 29009 Malaga, Spain
    Am J Clin Nutr 78:1092-7. 2003
  6. ncbi Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays
    Nicoletta Pellegrini
    Department of Public Health, University of Parma, Parma, Italy
    J Nutr 133:2812-9. 2003
  7. doi Lipid hydroperoxides from processed dietary oils enhance growth of hepatocarcinoma cells
    Nataliya V Rohr-Udilova
    Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria
    Mol Nutr Food Res 52:352-9. 2008
  8. ncbi Dietary red palm oil reduces ischaemia-reperfusion injury in rats fed a hypercholesterolaemic diet
    Maritza J Kruger
    Department of Physiological Sciences, University of Stellenbosch, Stellenbosch, 7600, South Africa
    Br J Nutr 97:653-60. 2007
  9. ncbi Suppression of fatty acid synthase promoter by polyunsaturated fatty acids
    Yang Soo Moon
    Department of Nutritional Sciences, University of California, Berkeley, CA 94720, USA
    J Lipid Res 43:691-8. 2002
  10. ncbi The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease
    Elaine B Feldman
    Medical College of Georgia, Augusta, GA, USA
    J Nutr 132:1062S-1101S. 2002

Detail Information

Publications191 found, 100 shown here

  1. ncbi Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions
    C N Serhan
    Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Physiol Pharmacol 51:643-54. 2000
    ..Moreover, they provide novel mechanism(s) that could underlie the many reported therapeutic benefits of omega-3 dietary supplementation of interest in inflammation, cancer, and vascular disorders...
  2. ncbi Dietary factors and growth and metabolism in experimental tumors
    Leonard A Sauer
    Bassett Research Institute, Cooperstown, NY 13326, USA
    J Nutr Biochem 18:637-49. 2007
    ....
  3. ncbi Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP Diet and Health Study cohort
    Anne C M Thiebaut
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Executive Plaza South Rm 3033, Bethesda, MD 20892, USA
    J Natl Cancer Inst 99:451-62. 2007
    ..Although ecologic association and animal studies support a direct effect of dietary fat on the development of breast cancer, results of epidemiologic studies have been inconclusive...
  4. ncbi Effect of dietary alpha-linolenic acid on the activity and gene expression of hepatic fatty acid oxidation enzymes
    T Ide
    Laboratory of Nutrition Biochemistry, National Food Research Institute, Ministry of Agriculture, Forestry and Fisheries, Tsukuba, Japan
    Biofactors 13:9-14. 2000
    ..It was suggested that both substrate specificities and alterations in the activities of the enzymes in beta-oxidation pathway play a significant role in the regulation of the serum lipid concentrations in rats fed alpha-18:3...
  5. ncbi Hypertension is related to the degradation of dietary frying oils
    Federico Soriguer
    Servicio de Endocrinologia y Nutricion, Hospital Civil Hospital Universitario Carlos Haya, Plaza del Hospital Civil, 29009 Malaga, Spain
    Am J Clin Nutr 78:1092-7. 2003
    ..The family kitchen resembles an uncontrolled laboratory experiment, and some discrepancies in the relation between the risk of hypertension and dietary fat may be partly due to the manipulation to which the fats were subjected...
  6. ncbi Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays
    Nicoletta Pellegrini
    Department of Public Health, University of Parma, Parma, Italy
    J Nutr 133:2812-9. 2003
    ..Such data, coupled with an appropriate questionnaire to estimate antioxidant intake, will allow the investigation of the relation between dietary antioxidants and oxidative stress-induced diseases...
  7. doi Lipid hydroperoxides from processed dietary oils enhance growth of hepatocarcinoma cells
    Nataliya V Rohr-Udilova
    Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria
    Mol Nutr Food Res 52:352-9. 2008
    ..2 cells, indicating the protective role of HO-1 induction. This is the first evidence that lipid hydroperoxides of dietary origin may be an important driving force for carcinogenesis in the liver...
  8. ncbi Dietary red palm oil reduces ischaemia-reperfusion injury in rats fed a hypercholesterolaemic diet
    Maritza J Kruger
    Department of Physiological Sciences, University of Stellenbosch, Stellenbosch, 7600, South Africa
    Br J Nutr 97:653-60. 2007
    ..This significant reduction in p38-MAPK was also associated with reduced apoptosis as indicated by significant reductions in caspase-3 and poly(ADP-ribose) polymerase cleavage...
  9. ncbi Suppression of fatty acid synthase promoter by polyunsaturated fatty acids
    Yang Soo Moon
    Department of Nutritional Sciences, University of California, Berkeley, CA 94720, USA
    J Lipid Res 43:691-8. 2002
    ..Using HepG2 cells, we further examined the specific FAS promoter elements required for PUFA suppression. We found that the -150 SRE, as well as the -65 E-Box, contribute to PUFA suppression of the FAS promoter, at least in vitro...
  10. ncbi The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease
    Elaine B Feldman
    Medical College of Georgia, Augusta, GA, USA
    J Nutr 132:1062S-1101S. 2002
    ....
  11. ncbi Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu
    R Palmantier
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina 27709, USA
    Cancer Res 61:2445-52. 2001
    ..Altogether, these data suggest that cis-PUFAs enhance human breast cancer cell adhesion to collagen IV by selectively activating specific PKC isozymes, which leads to the activation of beta1 integrins...
  12. ncbi Palm fruit chemistry and nutrition
    Kalyana Sundram
    Malaysian Palm Oil Board, P O Box 10620, 50720 Kuala Lumpur, Malaysia
    Asia Pac J Clin Nutr 12:355-62. 2003
    ..A further challenge would be to package all these palm ingredients into a single functional food for better nutrition and health...
  13. ncbi Flaxseed oil and inflammation-associated bone abnormalities in interleukin-10 knockout mice
    Stacey L Cohen
    Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada M5S 3E2
    J Nutr Biochem 16:368-74. 2005
    ....
  14. ncbi Dietary fish oil positively regulates plasma leptin and adiponectin levels in sucrose-fed, insulin-resistant rats
    Andrea S Rossi
    Dept of Biochemistry, School of Biochemistry, University of Litoral, Ciudad Universitaria, Paraje El Pozo C C 242, 3000 Santa Fe, Argentina
    Am J Physiol Regul Integr Comp Physiol 289:R486-R494. 2005
    ..These results suggest that increasing both adipokines by dietary FO might play an essential role in the normalization of insulin resistance and adiposity in dietary-induced, insulin-resistant models...
  15. ncbi An integrative metabolism approach identifies stearoyl-CoA desaturase as a target for an arachidonate-enriched diet
    David M Mutch
    Nestle Research Center, Vers chez les Blanc, Lausanne, Switzerland
    FASEB J 19:599-601. 2005
    ....
  16. ncbi Biological properties of olive oil phytochemicals
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Crit Rev Food Sci Nutr 42:209-21. 2002
    ....
  17. ncbi Diet and rheumatoid arthritis: a review of the literature
    Lisa K Stamp
    Department of Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, New Zealand
    Semin Arthritis Rheum 35:77-94. 2005
    ..A large number of patients seek alternative or complementary therapies of which diet is an important component. This article reviews the evidence for diet in rheumatoid arthritis along with the associated concept of oral tolerization...
  18. ncbi Dietary alpha-linolenic acid-rich diacylglycerols reduce body weight gain accompanying the stimulation of intestinal beta-oxidation and related gene expressions in C57BL/KsJ-db/db mice
    Takatoshi Murase
    Biological Science Laboratories, Kao Corporation, Ichikai, Haga, Tochigi 321 3497, Japan
    J Nutr 132:3018-22. 2002
    ..In addition, structural differences between DG and TG, not variations in the composition of fatty acids, are responsible for the different effects of the lipids...
  19. ncbi Effects of dietary fatty acids on the composition and oxidizability of low-density lipoprotein
    M Kratz
    Institute of Arteriosclerosis Research at the University of Münster, Munster, Germany
    Eur J Clin Nutr 56:72-81. 2002
    ..The objective of this study was to compare the effects of dietary monounsaturated fatty acids (MUFA), n-6 and n-3 polyunsaturated fatty acids (PUFA) on LDL composition and oxidizability...
  20. ncbi Chemistry of deep-fat frying oils
    E Choe
    Dept of Food and Nutrition, Inha Univ, Incheon, Korea
    J Food Sci 72:R77-86. 2007
    ..Antioxidant decreases the frying oil oxidation, but the effectiveness of antioxidant decreases with high frying temperature. Lignan compounds in sesame oil are effective antioxidants in deep-fat frying...
  21. ncbi Dietary virgin olive oil protects against lipid peroxidation and improves antioxidant status in the liver of rats chronically exposed to ethanol
    Abir Kasdallah-Grissa
    Faculty of Medicine, Laboratory of Biochemistry, UR03 ES 08 Human Nutrition and Metabolic Disorders, Monastir 5019, Tunisia
    Nutr Res 28:472-9. 2008
    ..In conclusion, results of this study indicate that olive oil ingestion by rats protects the liver from ethanol-induced oxidative damage by affecting the cellular redox potential...
  22. ncbi Vasculoprotective effects of oleic acid: epidemiological background and direct vascular antiatherogenic properties
    M Massaro
    Laboratory for Thrombosis and Vascular Research, CNR Institute of Clinical Physiology, Pisa, Italy
    Nutr Metab Cardiovasc Dis 12:42-51. 2002
    ....
  23. ncbi A long-term seal- and cod-liver-oil supplementation in hypercholesterolemic subjects
    J Brox
    Department of Clinical Chemistry, University Hospital of Tromsø, Norway
    Lipids 36:7-13. 2001
    ....
  24. ncbi Age-related mitochondrial DNA deletion in rat liver depends on dietary fat unsaturation
    Jose L Quiles
    Department of Physiology, Institute of Nutrition and Food Technology, University of Granada, Spain
    J Gerontol A Biol Sci Med Sci 61:107-14. 2006
    ..Results suggest that the age-related increase of the relative amount of deleted mtDNA depends on fat unsaturation. Moreover, the studied mtDNA deletion was correlated with mitochondrial oxidative stress and ultrastructural alterations...
  25. ncbi Dietary docosahexaenoic acid and immunocompetence in young healthy men
    D S Kelley
    USDA, ARS, Western Human Nutrition Research Center, Presidio of San Francisco, California 94129, USA
    Lipids 33:559-66. 1998
    ..Our results show that when total fat intake is low and held constant, DHA consumption does not inhibit many of the lymphocyte functions which have been reported to be inhibited by fish oil consumption...
  26. ncbi Differential regulation of hepatic apoptotic pathways by dietary olive and sunflower oils in the aging rat
    Rosario I Bello
    Departamento de Biologia Celular, Fisiologia e Inmunologia, Facultad de Ciencias, Universidad de Cordoba, Córdoba 14014, Spain
    Exp Gerontol 41:1174-84. 2006
    ....
  27. pmc The effect of dietary red palm oil on the functional recovery of the ischaemic/reperfused isolated rat heart: the involvement of the PI3-kinase signaling pathway
    Anna Mart Engelbrecht
    Department of Physiological Sciences, University of Stellenbosch, South Africa
    Lipids Health Dis 8:18. 2009
    ..9 +/- 3.4 pixels in RPO + Wm). We have also demonstrated that PI3-K inhibition induced PARP cleavage (marker of apoptosis) in the hearts during ischaemia/reperfusion injury and that RPO supplementation counteracted this effect...
  28. ncbi The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial
    Maria Isabel Covas
    Municipal Institute for Medical Research, Barcelona, Spain
    Ann Intern Med 145:333-41. 2006
    ..Little information is available on the effect of the phenolic compounds of olive oil on plasma lipid levels. No international study with a large sample size has been done...
  29. ncbi Dietary fatty acids and cancer
    D P Rose
    Division of Nutrition and Endocrinology, American Health Foundation, Valhalla, NY 10595, USA
    Am J Clin Nutr 66:998S-1003S. 1997
    ....
  30. ncbi Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers
    H Bartsch
    Division of Toxicology and Cancer Risk Factors, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Carcinogenesis 20:2209-18. 1999
    ....
  31. ncbi Docosahexaenoic acid suppresses the activity of peroxisome proliferator-activated receptors in a colon tumor cell line
    Joo Y Lee
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA
    Biochem Biophys Res Commun 298:667-74. 2002
    ..These results suggest that PPAR-mediated gene expression and cellular responses can be dynamically modulated by different types of dietary fatty acids consumed...
  32. ncbi Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene
    R W Owen
    Division of Toxicology and Cancer Risk Factors, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Food Chem Toxicol 38:647-59. 2000
    ..29 +/- 2.56). All classes of phenolics were shown to be potent antioxidants. In future epidemiologic studies, both the nature and source of olive oil consumed should be differentiated in ascertaining cancer risk...
  33. ncbi Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil
    Paola Bogani
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Atherosclerosis 190:181-6. 2007
    ..These data reinforce the notion that the Mediterranean diet reduces the incidence of coronary heart disease partially due to the protective role of its phenolic components, including those of extra virgin olive oil...
  34. ncbi Dietary intake of essential and long-chain polyunsaturated fatty acids in pregnancy
    Elizabeth D Loosemore
    University of Connecticut, Department of Nutritional Sciences, Storrs, CT 06269 4017, USA
    Lipids 39:421-4. 2004
    ..We conclude that replacing dietary sources of SFA with those of EFA and LCPUFA, especially n-3 LCPUFA, would benefit the dietary fat profiles of all pregnant women...
  35. ncbi Mechanisms by which botanical lipids affect inflammatory disorders
    Floyd H Chilton
    Center for Botanical Lipids, Wake Forest University, Winston Salem, NC, USA
    Am J Clin Nutr 87:498S-503S. 2008
    ..Echium oil and other oils containing stearidonic acid as well as botanical oil combinations (such as echium and borage oils) hold great promise for modulating inflammatory diseases...
  36. ncbi The effect of dietary fish oil-supplementation to healthy young men on oxidative burst measured by whole blood chemiluminescence
    Stine Bartelt
    Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Rolighedsvej 30, DK 1958 Frederiksberg C, Denmark
    Br J Nutr 99:1230-8. 2008
    ..44, P = 0.016), suggesting a dose-response relationship. These results indicate that n-3 LCPUFA may have immuno-stimulating effects...
  37. ncbi Oily fish reduces plasma triacylglycerols: a primary prevention study in overweight men and women
    Carmel S Moore
    Medical Research Council Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, UK
    Nutrition 22:1012-24. 2006
    ..It tested whether decreases in LA:LNA modulate effects of LC omega-3 PUFA...
  38. ncbi The effects of feeding fish oil on uterine secretion of PGF2alpha, milk composition, and metabolic status of periparturient Holstein cows
    R Mattos
    Department of Animal Sciences, University of Florida, Gainesville 32611 0920, USA
    J Dairy Sci 87:921-32. 2004
    ..Feeding FO reduced plasma concentrations of glucose. Dietary fatty acids given during the periparturient period can reduce the uterine secretion of PGF2alpha in lactating dairy cows and alter the fatty acid profile of milk fat...
  39. ncbi Virgin olive oil normalizes the altered triacylglycerol molecular species composition of adipose tissue in spontaneously hypertensive rats
    Javier S Perona
    Instituto de la Grasa CSIC, Avenida Padre Garcia Tejero 4, 41012 Seville, Spain
    J Agric Food Chem 52:4227-33. 2004
    ..Therefore, it was concluded that although oleic acid-rich diets improve some of the altered parameters of SHR adipose tissue, VOO is more effective than HOSO in this regard...
  40. ncbi Influence of parturition and diets enriched in n-3 or n-6 polyunsaturated fatty acids on immune response of dairy cows during the transition period
    M Lessard
    Dairy and Swine Research and Development Centre, Agriculture and Agri Food Canada, Lennoxville, QC, Canada J1M 1Z3
    J Dairy Sci 87:2197-210. 2004
    ..In conclusion, functional properties of lymphocytes and monocyte/macrophage lineage of dairy cows during the transition period are modulated by parturition and the composition of polyunsaturated fatty acids in the diet...
  41. ncbi Effects of dietary fat and oxidized cholesterol on gene expression in rat liver as assessed by cDNA expression array analysis
    Robert Ringseis
    Institut fur Ernahrungswissenschaften, Martin Luther Universitat Halle Wittenberg, Emil Abderhalden Strasse 26, 06108, Halle Saale, Germany
    Eur J Nutr 44:231-41. 2005
    ..However, the various biological effects of oxysterols such as cytotoxicity, atherogenicity or mutagenicity suggest that other genes may be also affected by oxysterols than lipid metabolism...
  42. ncbi Dietary fatty acid composition affects the repeat swimming performance of Atlantic salmon in seawater
    G N Wagner
    Faculty of Agricultural Science, University of British Columbia, 266B 2357 Main Mall, Vancouver, BC Canada V6T 1Z4
    Comp Biochem Physiol A Mol Integr Physiol 137:567-76. 2004
    ..g. SO diet). Lipid supplements consisting largely of vegetable oils did not compromise fish cardiorespiratory physiology under the conditions of this study...
  43. ncbi Dietary PUFA and the metabolic syndrome in Indian Asians living in the UK
    Louise M Brady
    Hugh Sinclair Human Nutrition Unit, School of Food Biosciences, PO Box 226, University of Reading, White Knights, Reading RG6 6AP, UK
    Proc Nutr Soc 63:115-25. 2004
    ..The present study concludes that, contrary to the central hypothesis, the prevalence of metabolic abnormalities in Indian Asians compared with Caucasians may not be attributable to differences in intakes of n-6 and n-3 PUFA...
  44. ncbi Influence of dietary lipid source and strain on fatty acid composition of Muscovy duck meat
    A Schiavone
    Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Universita di Torino, Grugliasco, Italy
    J Anim Physiol Anim Nutr (Berl) 88:88-93. 2004
    ..e. off-flavours) must be evaluated...
  45. ncbi Importance of seafood as nutrient source in the diet of Belgian adolescents
    I Sioen
    Department of Public Health, and Department of Food Safety and Food Quality, Ghent University, Ghent, Belgium
    J Hum Nutr Diet 20:580-9. 2007
    ..The aim of this study was to investigate the importance of seafood as a nutrient source in adolescents' diet and the extent to which seafood consumption can increase the intake of omega-3 polyunsaturated fatty acids and vitamin D...
  46. ncbi Fish-oil esters of plant sterols improve the lipid profile of dyslipidemic subjects more than do fish-oil or sunflower oil esters of plant sterols
    Isabelle Demonty
    School of Dietetics and Human Nutrition, McGill University, Sainte Anne de Bellevue, Canada
    Am J Clin Nutr 84:1534-42. 2006
    ..Fish-oil fatty acid esters of plant sterols (FO-PS) were shown to have hypotriglyceridemic and hypocholesterolemic properties in animal models...
  47. ncbi Replacement of dietary fish oil for Atlantic salmon parr (Salmo salar L.) with a stearidonic acid containing oil has no effect on omega-3 long-chain polyunsaturated fatty acid concentrations
    Matthew R Miller
    School of Aquaculture, Tasmanian Aquaculture and Fisheries Institute, University of Tasmania, Locked Bag 1370, Launceston, Tasmania, Australia
    Comp Biochem Physiol B Biochem Mol Biol 146:197-206. 2007
    ..The balance between increased biosynthesis and retention of omega3 LC-PUFA to maintain the concentrations observed in the SO fed fish remains to be conclusively determined, and further studies are needed to ascertain this...
  48. ncbi Fatty acids in liver, muscle and gonad of three tropical rays including non-methylene-interrupted dienoic fatty acids
    Mohamed Vall Ould El Kebir
    Laboratoire de Phytochimie de Marseille, UMR CNRS 6171, Faculte des Sciences et Techniques de Saint Jerome, Universite Paul Cezanne, Case 531, Avenue Escadrille Normandie Niemen, 13397 Marseille Cedex 20, France
    Lipids 42:525-35. 2007
    ..These acids are quite unusual in fish and unprecedented in rays. The 22:2 Delta6,14 acid occurred in gonads of male specimens of R. cemiculus at 2.9%...
  49. ncbi Phospholipid fatty acid composition and diamine oxidase activity of intestinal mucosa from rats treated with irinotecan hydrochloride (CPT-11) under vegetable oil-enriched diets: comparison between perilla oil and corn oil
    Makoto Usami
    Division of Surgical Metabolism, Faculty of Health Science, Kobe University School of Medicine, 7 10 2 Tomogaoka, Suma ku, Kobe 654 0142, Japan
    JPEN J Parenter Enteral Nutr 30:124-32. 2006
    ..The effect of dietary vegetable oil supplementation, perilla oil vs corn oil, was also evaluated...
  50. ncbi Immune modulation by parenteral lipid emulsions
    Geert J A Wanten
    Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
    Am J Clin Nutr 85:1171-84. 2007
    ....
  51. ncbi Effects of dietary saturated, monounsaturated, and n-3 fatty acids on blood pressure in healthy subjects
    Birthe M Rasmussen
    Department of Clinical Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark
    Am J Clin Nutr 83:221-6. 2006
    ..Although the effect of diet on plasma lipids and lipoproteins is well documented, less information exists on the role of fats on blood pressure (BP)...
  52. ncbi Paradoxical effect of n-3-containing vegetable oils on long-chain n-3 fatty acids in rat heart
    Leslie G Cleland
    Hanson Institute and Rheumatology Unit, Royal Adelaide Hospital, SA, Australia
    Lipids 40:995-8. 2005
    ..e., flaxseed > echium > canola > sunflower oil. This paradox may be explained by lower ALA intake leading to decreased competition for Delta6 desaturase activity between ALA and the 24:5n-3 FA precursor to DHA formation...
  53. ncbi High-concentrate diets and polyunsaturated oils alter trans and conjugated isomers in bovine rumen, blood, and milk
    J J Loor
    Herbivore Research Unit INRA Theix, 63122 St Genes Champanelle, France
    J Dairy Sci 88:3986-99. 2005
    ....
  54. ncbi Does enteral nutrition of dietary polyunsaturated fatty acids promote oxidative stress and tumour growth in ductal pancreatic cancer? Experimental trial in Syrian Hamster
    J I Gregor
    Clinic of General, Visceral, Vascular and Thoracic Surgery, Charite Campus Mitte, Humbold University of Berlin, 10117 Berlin, Germany
    Prostaglandins Leukot Essent Fatty Acids 74:67-74. 2006
    ..Thus we investigated the effects of n-3, n-6 and n-9 polyunsaturated fatty acids (PUFA) on oxidative stress (lipidperoxidation) and tumour growth in ductal pancreatic cancer...
  55. ncbi Influence of dietary fats on weight gain in albino rats
    Nandita Pereira
    Department of Physiology, Goa Medical College, Bambolim, Goa 403 202
    Indian J Physiol Pharmacol 49:206-12. 2005
    ..001), yet weight gain was similar. Thus it appears that carbon-chain length and degree of saturation of dietary fat does not influence weight gain in rats fed an ad libitum diet...
  56. ncbi [Dietary fatty acids and experimental carcinogenesis]
    Philippe Bougnoux
    INSERM E 0211, Equipe de recherche Nutrition, Croissance et Cancer, CORAD, CHU de Tours 2, boulevard Tonnellé 37044 Tours Cedex
    Bull Cancer 92:685-96. 2005
    ..On the other hand, an excessive consumption of n-6 PUFAs and of saturated fatty acids could promote colon cancers...
  57. ncbi [Unsaturated fatty acids intake and breast cancer risk: epidemiological data review]
    Anne C M Thiebaut
    Equipe E3N EPIC, INSERM, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex
    Bull Cancer 92:658-69. 2005
    ..However, it is difficult in human to disentangle the effect of nutrient intake from that of contributing foods or even nutritional profile...
  58. ncbi Restoration of depressed prostanoid-induced ileal contraction in spontaneously hypertensive rats by dietary fish oil
    Glen S Patten
    CSIRO Health Sciences and Nutrition, Adelaide, South Australia 5000, Australia
    Lipids 40:69-79. 2005
    ....
  59. ncbi Partial replacement of dietary fish oil with blends of vegetable oils (rapeseed, linseed and palm oils) in diets for European sea bass (Dicentrarchus labrax L.) over a long term growth study: effects on muscle and liver fatty acid composition and effectiv
    G Mourente
    Departamento de Biologia, Facultad de Ciencias del Mar y Ambientales, Universidad de Cadiz, E 11510 Puerto Real Cádiz, Spain
    Comp Biochem Physiol B Biochem Mol Biol 145:389-99. 2006
    ..95 g of EPA+DHA for fish fed FO or 60% VO, respectively. Therefore, sea bass grown for most of the production cycle using diets containing 60% VO can still contribute a significant quantity of healthy n-3 HUFA to the human consumer...
  60. ncbi The Mediterranean vs the Japanese diet
    S Tokudome
    Eur J Clin Nutr 58:1323; author reply 1324-5. 2004
  61. ncbi Dietary alpha-linolenic acid lowers postprandial lipid levels with increase of eicosapentaenoic and docosahexaenoic acid contents in rat hepatic membrane
    H K Kim
    Department of Food and Nutrition, Seoul National University, Korea
    Lipids 36:1331-6. 2001
    ..These results suggest that n-3 ALA has more of a hypolipidemic effect than n-6 LA and that the hypolipidemic effect of n-3 PUFA may be partly related to the increase of EPA and DHA in hepatic membrane...
  62. ncbi Dietary n-3 and n-6 fatty acids alter avian metabolism: metabolism and abdominal fat deposition
    Ronald E Newman
    Faculty of Veterinary Science, University of Sydney, Camden, NSW, Australia
    Br J Nutr 88:11-8. 2002
    ..In addition, the PUFA-rich diets lowered plasma concentrations of serum triacylglycerols and cholesterol. The findings indicate that dietary fatty acid profile influences nutrient partitioning in broiler chickens...
  63. ncbi Fatty acid compositions of serum phospholipids of postmenopausal women: a comparison between Greenland Inuit and Canadians before and after supplementation with fish oil
    Ken D Stark
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Nutrition 18:627-30. 2002
    ....
  64. ncbi Cardiac membrane fatty acid composition modulates myocardial oxygen consumption and postischemic recovery of contractile function
    Salvatore Pepe
    Cardiac Surgical Research Unit, Alfred Hospital and Baker Medical Research Institute, Monash University Faculty of Medicine, Melbourne, Australia
    Circulation 105:2303-8. 2002
    ..Fish oils modify cardiac membrane phospholipid fatty acid composition with potent antiarrhythmic effects. We tested the effects of dietary fish oil on ventricular hemodynamics and myocardial oxygen consumption (MVO2)...
  65. ncbi On the reanalysis of the GISSI-Prevenzione
    Alexander Leaf
    Circulation 105:1874-5. 2002
  66. ncbi Digestion and deposition of individual fatty acids in growing-finishing pigs fed diets containing either beef tallow or sunflower oil
    J Mitchaothai
    Department of Clinic for Swine, Faculty of Veterinary Medicine, Mahanakorn University of Technology, Nong Chok, Bangkok, Thailand
    J Anim Physiol Anim Nutr (Berl) 92:502-10. 2008
    ..It is concluded that the feeding of a diet with sunflower oil instead of beef tallow improved apparent digestibility of SFA, MUFA and PUFA, increased the deposition:digestible intake ratio for SFA, but lowered that for MUFA and PUFA...
  67. ncbi n-3 Deficient and docosahexaenoic acid-enriched diets during critical periods of the developing prenatal rat brain
    Mark Schiefermeier
    Department of Neurobiology, Weizmann Institute of Science, 76100 Rehovot, Israel
    J Lipid Res 43:124-31. 2002
    ..Thus the content of fetal brain DHA in n-3 deficient embryos could be restored within 48 hours. Dietary manipulation of fetal tissues is a rapid phenomenon and can be used to enrich DHA at critical periods of development in utero...
  68. ncbi The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids
    K M Botham
    Department of Physiology, University of the Basque Country, Medical School, Bilbao, Spain
    Biochim Biophys Acta 1534:96-109. 2001
    ....
  69. ncbi Effect of dietary polyunsaturated fatty acids on uterine prostaglandin synthesis in the cow
    Z Cheng
    Reproduction and Development Group, Department of Veterinary Basic Sciences, Royal Veterinary College, Boltons Park, Hawkshead Road, Potters Bar, Hertfordshire EN6 1NB, UK
    J Endocrinol 171:463-73. 2001
    ..These data suggest that a high n-6 diet reduces the endometrial capacity to produce PGs and may therefore have implications for the control of luteolysis and other PG-mediated events such as ovulation...
  70. ncbi Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: level of n-6 fatty acids as another critical factor
    A Ikemoto
    Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabedori, Mizuhoku, Nagoya 467-8603, Japan
    J Lipid Res 42:1655-63. 2001
    ....
  71. ncbi n-3 enrichment of chicken meat. 1. Use of very long-chain fatty acids in chicken diets and their influence on meat quality: fish oil
    S López-Ferrer
    Department of Ciència Animal i dels Aliments, Facultat de Veterinaria, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Poult Sci 80:741-52. 2001
    ..After 1 wk of T4, the DHA levels in chicken decreased. Sensory panelists could not identify the meats from T4 and T5 as being different from the control diet (T1)...
  72. pmc Comparison of the effects of dietary n-3 and n-6 polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants
    X Zheng
    Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College St, London NW1 0TU, UK
    Biochem J 357:481-7. 2001
    ....
  73. ncbi Lipid oxidation in fresh and spray-dried eggs enriched with omega3 and omega6 polyunsaturated fatty acids during storage as affected by dietary vitamin E and canthaxanthin supplementation
    J Galobart
    , , , Spain
    Poult Sci 80:327-37. 2001
    ..On the other hand, CX supplementation did not prevent lipid oxidation in PUFA-enriched eggs. Moreover, no synergistic effect between both compounds was detected...
  74. ncbi Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate
    J V Higdon
    Department of Nutrition and Food Management, Oregon State University, Corvallis, OR 97331, USA
    J Lipid Res 42:407-18. 2001
    ..H. Du, Y. S. Lee, T. Wu, and R. C. Wander. Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate. J. Lipid Res. 2001. 42: 407--418...
  75. ncbi Enhanced level of n-3 fatty acid in membrane phospholipids induces lipid peroxidation in rats fed dietary docosahexaenoic acid oil
    J H Song
    Department of Applied Biological Chemistry, Faculty of Agriculture, Tohoku University, 981-8555, Sendai, Japan
    Atherosclerosis 155:9-18. 2001
    ....
  76. ncbi Transfer of n-3 and n-6 polyunsaturated fatty acids from yolk to embryo during development of the king penguin
    F Decrock
    , Centre National de la Recherche Scientifique, , 67087 Strasbourg, France
    Am J Physiol Regul Integr Comp Physiol 280:R843-53. 2001
    ..Thus both 22:6(n-3) and 20:4(n-6), which are, respectively, abundant and deficient in the yolk, undergo biomagnification during transfer to the embryo...
  77. ncbi Inhibition of intracellular peroxides and apoptosis of lymphocytes in lupus-prone B/W mice by dietary n-6 and n-3 lipids with calorie restriction
    C P Reddy Avula
    University of Texas Health Science Center, Department of Medicine, San Antonio 78229 3900, USA
    J Clin Immunol 22:206-19. 2002
    ..In summary, CR resulted in decreased apoptosis accompanied by alterations in Fas, Fas-L, and Bcl-2 expression in old mice, increased life span, and delayed onset of kidney disease...
  78. ncbi Effects of n-3 polyunsaturated dietary supplementation on the reproductive capacity of male turkeys
    E Blesbois
    Station de Recherches Avicoles, INRA, F 37380 Nouzilly, France
    Theriogenology 61:537-49. 2004
    ..These results indicate that an increase in the dietary ratio of n-3/n-6 PUFAs is valuable to sustain the reproductive capacity of male turkeys especially when they are getting older...
  79. ncbi Effects of dietary n-3 polyunsaturated fatty acids, breed and dietary vitamin E on the fatty acids of lamb muscle, liver and adipose tissue
    G Demirel
    Division of Farm Animal Science, School of Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU, UK
    Br J Nutr 91:551-65. 2004
    ..Different combinations of dietary fatty acids and better protection against rumen biohydrogenation are required to improve muscle PUFA : saturated fatty acids ratios...
  80. ncbi Biohydrogenation of dietary n-3 PUFA and stability of ingested vitamin E in the rumen, and their effects on microbial activity in sheep
    S Chikunya
    ASRC, Harper Adams University College, School of Agriculture, Edgmond, Newport, Shropshire TF10 8NB, UK
    Br J Nutr 91:539-50. 2004
    ..Although alpha-tocopheryl acetate resisted degradation in the rumen, plasma vitamin E status remained deficient to borderline, suggesting either that uptake may have been impaired or metabolism post-absorption increased...
  81. ncbi Diets rich in saturated and polyunsaturated fatty acids: metabolic shifting and cardiac health
    Yeda Sant ana Diniz
    Department of Clinical Cardiology, Faculty of Medicine, University of Sao Paulo State, Botucatu, Sao Paulo, Brazil
    Nutrition 20:230-4. 2004
    ..The aim of this study was to determine the effects of diets rich in saturated and polyunsaturated fatty acids on metabolic pathways and the relation of metabolic shifting to oxidative stress in cardiac tissue...
  82. ncbi Astrocytes in culture require docosahexaenoic acid to restore the n-3/n-6 polyunsaturated fatty acid balance in their membrane phospholipids
    Gaelle Champeil-Potokar
    Laboratoire de Nutrition et Securite Alimentaire, Institut National de la Recherche Agronomique, Jouy en Josas, France
    J Neurosci Res 75:96-106. 2004
    ..This reliable method of altering membrane phospholipid composition promises to be useful for studying the influence of n-6/n-3 imbalance on astrocyte function...
  83. ncbi Replacement of dietary fish oils by alpha-linolenic acid-rich oils lowers omega 3 content in tilapia flesh
    Ioannis T Karapanagiotidis
    Institute of Aquaculture, University of Stirling, Stirling, FK9 4LA, Scotland
    Lipids 42:547-59. 2007
    ....
  84. ncbi Cholesterol synthesis in mice is suppressed but lipofuscin formation is not affected by long-term feeding of n-3 fatty acid-enriched oils compared with lard and n-6 fatty acid-enriched oils
    Chunyan Du
    Department of Preventive Nutraceutical Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
    Biol Pharm Bull 26:766-70. 2003
    ....
  85. ncbi Effects of lifestyle modification and lipid intake variations on patients with peripheral vascular disease
    Teresa Nestares
    Institute of Nutrition and Food Technology, Department of Physiology, University of Granada
    Int J Vitam Nutr Res 73:389-98. 2003
    ..The lifestyle intervention program, together with a high intake of olive plus fish oil, seems to produce important beneficial effects in nutritional management, physical performance, and clinical parameters of PVD patients...
  86. pmc n-3 polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis
    B Wen
    , Institut Gustave Roussy, 39, rue Camille Desmoulins, , France
    Br J Cancer 89:1102-7. 2003
    ..The magnitude of the differential effect suggests that n-3 PUFAs need to be further investigated in the clinic...
  87. ncbi Altered fatty acid compositions in atlantic salmon (Salmo salar) fed diets containing linseed and rapeseed oils can be partially restored by a subsequent fish oil finishing diet
    J Gordon Bell
    Institute of Aquaculture, University of Stirling, Stirling, FK9 4LA, Scotland, UK
    J Nutr 133:2793-801. 2003
    ....
  88. ncbi Maternal dietary N-3 fatty acids alter the spleen fatty acid composition and bovine serum albumin-induced wing web swelling in broilers
    Y W Wang
    Poult Sci 81:1722-7. 2002
    ..In conclusion, n-3 PUFA in breeder hen diets suppressed the BSA-induced wing web swellings of the hens, increased the spleen n-3 fatty acids (especially DHA), and decreased BSA-induced wing web swellings of progeny up to 4 wk of age...
  89. ncbi Accumulation of alpha-tocopherol in eggs enriched with omega3 and omega6 polyunsaturated fatty acids
    J Galobart
    Departament de Ciencia Animal i dels Aliments, Facultat Veterinària, Universitat Autonoma de Barcelona, E 08193 Bellaterra, Spain
    Poult Sci 81:1873-6. 2002
    ..No differences were observed between dietary oils in the deposition pattern of alpha-Toc in the egg...
  90. ncbi [Possibilities for correction of n-3 fatty acids insufficiency in the Hungarian population]
    József Perédi
    Elelmiszertudományi Kar, Gabona és Iparinövény Technológiai Tanszék, Szent Istvan Egyetem, Budapest
    Orv Hetil 143:2587-91. 2002
    ..The author has presented presumable reasons of this deficiency, and has highlighted that production, marketing and consumption of special 'functional foods', rich in n-3 fatty acids may considerably improve this unfavourable situation...
  91. ncbi Long-term supplementation of various dietary lipids alters bone mineral content, mechanical properties and histological characteristics of Japanese quail
    D Liu
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    Poult Sci 82:831-9. 2003
    ..These results suggest that long-term exposure to a FO or HSBO diet have a significant beneficial effect on bone metabolism...
  92. ncbi Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects
    Yvonne E Finnegan
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, United Kingdom
    Am J Clin Nutr 77:783-95. 2003
    ....
  93. ncbi [The role of omega-3 fatty acids in the treatment of bipolar disorders: the current situation]
    C Sempels
    Universitair Psychiatrisch Centrum Katholieke Universiteit Leuven, campus Kortenberg, Belgie
    Tijdschr Psychiatr 49:639-47. 2007
    ..Epidemiological investigations show that a high consumption of omega-3 fatty acids is in inverse proportion to the prevalence of affective disorders...
  94. ncbi Development of a gas chromatographic/mass spectrometric method for determination of phthalates in oily foods
    Anna Sannino
    Stazione Sperimentale per l Industria delle Conserve Alimentari, Food Safety Department, Viale F Tanara 31 A 43100 Parma, Italy
    J AOAC Int 93:315-22. 2010
    ..LOQs were 0.050-0.10 mg/kg for all the target compounds except di-isononyl phthalate, di-isodecyl phthalate, and DINCH (2.0 mg/kg)...
  95. doi Oxidative stability and shelf-life evaluation of selected culinary oils
    S Parkash Kochhar
    Nutrition and Food Science Group, School of Life Sciences, Oxford Brookes University, Oxford, UK
    Int J Food Sci Nutr 60:289-96. 2009
    ....
  96. ncbi No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals
    G K Pot
    Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    Eur J Clin Nutr 63:1353-9. 2009
    ..Therefore, we determined the effects of fish oil supplementation on 19 serum inflammatory markers and their interrelationships in healthy, middle-aged individuals...
  97. ncbi Consumption of virgin olive oil influences membrane lipid composition and regulates intracellular signaling in elderly adults with type 2 diabetes mellitus
    Javier S Perona
    Nutrition and Lipid Metabolism, Instituto de la Grasa CSIC, Av Padre Garcia Tejero, 4, 41012 Sevilla, Spain
    J Gerontol A Biol Sci Med Sci 62:256-63. 2007
    ..These combined effects probably account for the positive effects of VOO on glycemic homeostasis...
  98. ncbi HPV-induced recurrent laryngeal papillomatosis: dietary fatty acid and micronutrient intakes
    Louise Louw
    Department of Otorhinolaryngology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa
    Asia Pac J Clin Nutr 17:352-7. 2008
    ..It is imperative to ensure that children with RLP receive proper nutrition and follow a healthy lifestyle to prevent disease recurrence after treatment...
  99. ncbi Whole body distribution of deuterated linoleic and alpha-linolenic acids and their metabolites in the rat
    Yu Hong Lin
    Section of Nutritional Neuroscience, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 9410, USA
    J Lipid Res 48:2709-24. 2007
    ..Approximately 6.0% of D5-18:3n-3 and 2.6% of D5-18:2n-6 were elongated/desaturated and stored, mainly in muscle, adipose, and the carcass. The remaining 78% of both precursors was apparently catabolized or excreted...
  100. ncbi Short-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice
    Janneke de Wilde
    Nutrigenomics Consortium, Top Institute Food and Nutrition, Wageningen, The Netherlands
    Physiol Genomics 32:360-9. 2008
    ..Together with increased saturation of phospholipids of the mitochondrial membrane this can result in decreased mitochondrial function, which is a hallmark observed in insulin resistance and Type 2 diabetes...
  101. doi Studies on the protective effect of dietary fish oil on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney
    Shubha Priyamvada
    Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, U P, India
    Prostaglandins Leukot Essent Fatty Acids 78:369-81. 2008
    ..Dietary FO supplementation ameliorated GM-induced specific metabolic alterations and oxidative damage due to its intrinsic biochemical/antioxidant properties...

Research Grants121 found, 100 shown here

  1. UC Davis Clinical and Translational Science Center
    Lars Berglund; Fiscal Year: 2007
    ..The UC Davis CTSC will be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
  2. Regulation of Lipoprotein(a) Metabolism in Humans with Reference to Ethnicity
    LARS F BERGLUND; Fiscal Year: 2010
    ..The proposal aims to understand which inherited factors affect Lipoprotein(a) and how this factor causes disease. The results will be important to design treatments. ..
  3. NUTRITION COUNSELING TO REDUCE CARDIOVASCULAR RISKS IN HYPERCHOLESTEROLEMIA
    Penny Kris Etherton; Fiscal Year: 2000
    ..g. eat more whole grain bread products and less saturated fat from animal products) compared with usual care study participants. ..
  4. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2008
    ....
  5. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2010
    ....
  6. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2007
    ....
  7. COMPARE DIET, LIFE STYLE, CARDIOVASCULAR DISEASE RISK
    Penny Kris Etherton; Fiscal Year: 2000
    ..abstract_text> ..
  8. SOY PROTEIN AND PLAMA LIPIDS. LIPOPROTEINS, VASCULAR REACTIVITY, CAM, PLATELETS
    Penny Kris Etherton; Fiscal Year: 2000
    ..The soy protein will be incorporated into baked goods and snack foods in a very palatable way. The investigators hope to learn more about recognized effects of soy intake on the reduction of risk for heart disease. ..
  9. NUTRITION COUNSELING TO REDUCE CARDIOVASCULAR RISKS IN HYPERCHOLESTEROLEMIA
    Penny Kris Etherton; Fiscal Year: 2001
    ..g. eat more whole grain bread products and less saturated fat from animal products ) compared with usual care study participants. ..
  10. NUTRITION COUNSELING TO REDUCE CARDIOVASCULAR RISKS IN HYPERCHOLESTEROLEMIA
    Penny Kris Etherton; Fiscal Year: 2001
    ..g. eat more whole grain bread products and less saturated fat from animal products ) compared with usual care study participants. ..
  11. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2006
    ....
  12. Fatty Acids and Cardiovascular Health
    Dariush Mozaffarian; Fiscal Year: 2007
    ..End of Abstract) [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  13. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2007
    ....
  14. NUTRITION COUNSELING TO REDUCE CARDIOVASCULAR RISKS IN HYPERCHOLESTEROLEMIA
    Penny Kris Etherton; Fiscal Year: 2002
    ..g. eat more whole grain bread products and less saturated fat from animal products ) compared with usual care study participants. ..
  15. NUTRITION COUNSELING TO REDUCE CARDIOVASCULAR RISKS IN HYPERCHOLESTEROLEMIA
    Penny Kris Etherton; Fiscal Year: 2002
    ..g. eat more whole grain bread products and less saturated fat from animal products ) compared with usual care study participants. ..
  16. NUTRITION COUNSELING TO REDUCE CARDIOVASCULAR RISKS IN HYPERCHOLESTEROLEMIA
    Penny Kris Etherton; Fiscal Year: 2000
    ..g. eat more whole grain bread products and less saturated fat from animal products ) compared with usual care study participants. ..
  17. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  18. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2008
    ....
  19. Mercury, Selenium, and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2010
    ....
  20. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  21. Mercury, Selenium and Risk of Cardiovascular Disease in Women and Men
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  22. Fatty Acids and Major Cardiovascular Outcomes
    Dariush Mozaffarian; Fiscal Year: 2009
    ....
  23. Brain LC-PUFAs and Maternal Mental Health
    Beth Levant; Fiscal Year: 2004
    ..These findings will also suggest novel treatments for such illnesses when they occur. ..
  24. Brain LC-PUFAs and Maternal Mental Health
    Beth Levant; Fiscal Year: 2006
    ..These findings will also suggest novel treatments for such illnesses when they occur. ..
  25. Multicenter Therapeutic Trials of X-Linked ALD
    Hugo Moser; Fiscal Year: 2003
    ....
  26. Multicenter Therapeutic Trials of X-Linked ALD
    Hugo Moser; Fiscal Year: 2004
    ....
  27. Multicenter Therapeutic Trials of X-Linked ALD
    Hugo Moser; Fiscal Year: 2005
    ....
  28. Brain LC-PUFAs and Maternal Mental Health
    Beth Levant; Fiscal Year: 2005
    ..These findings will also suggest novel treatments for such illnesses when they occur. ..
  29. Multicenter Therapeutic Trails of X-Linked ALD Supplement
    Hugo Moser; Fiscal Year: 2005
    ..This would facilitate and speed the evaluation of all therapeutic interventions in AMN. These techniques may also be applicable to the study of other spinal cord disorders. ..
  30. Brain DHA, Dopamine, and Behavior: Roles in ADHD
    Beth Levant; Fiscal Year: 2006
    ..Such insights may identify a means by which certain risk factors for ADHD may be reduced or eliminated or the severity of the disease may be reduced through appropriate pre- and postnatal nutrition. [unreadable] [unreadable]..
  31. THERAPEUTIC TRIALS OF X-LINKED ALD: PHASE III; LORENZO*
    Hugo Moser; Fiscal Year: 2006
    ..It is now recognized that 50% of heterozygous develop pure AMN which may lead to considerable disability. This is the first therapeutic study that also involves women heterozygous for X-ALD. [unreadable] [unreadable]..
  32. Multicenter Therapeutic Trials of X-Linked ALD
    Hugo Moser; Fiscal Year: 2002
    ....
  33. Brain DHA, Dopamine, and Behavior: Roles in ADHD
    Beth Levant; Fiscal Year: 2005
    ..Such insights may identify a means by which certain risk factors for ADHD may be reduced or eliminated or the severity of the disease may be reduced through appropriate pre- and postnatal nutrition. ..
  34. The Wake Forest and Harvard Center for Botanical Lipids
    FLOYD CHILTON; Fiscal Year: 2007
    ..These interactive and synergistic studies have a strong scientific basis and are likely to provide new understanding regarding the treatment of chronic inflammatory diseases such as atherosclerosis and asthma with botanical oils...
  35. Fatigue, depression, and inflammation in cancer survivors: A prospective study
    Janice Kiecolt Glaser; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  36. The Environmental Determinants of Diabetes in Young (TEDDY0
    Olli Simell; Fiscal Year: 2008
    ..Participants will be followed to the age of 15 years. Identification of such etiologically important factors will lead to a better understanding of disease pathogenesis and result in new strategies to prevent, delay or reverse T1D. ..
  37. DIETARY FAT REGULATION OF HEPATIC GENE EXPRESSION
    DONALD JUMP; Fiscal Year: 2009
    ..Determine how over expression of specific fatty acid elongases affects hepatic function, blood lipid composition and the onset of chronic disease. ..
  38. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2005
    ..abstract_text> ..
  39. Prospective Epidemiological Study of ALS
    Alberto Ascherio; Fiscal Year: 2009
    ..abstract_text> ..
  40. Niacin, n-3 fatty acids and insulin resistance
    William Harris; Fiscal Year: 2006
    ..This should lead to more effective therapy for the dyslipidemia of insulin resistance and ultimately to reduced risk for CHD in this burgeoning patient population. ..
  41. Intermittent food restriction prevents mammary tumors
    MARGOT CLEARY; Fiscal Year: 2007
    ..Our long-term objectives are to establish nutrition intervention strategies applicable to humans and/or to provide insights leading to the development of chemopreventive agents to mimic this protective effect. [unreadable] [unreadable]..
  42. Postprandial glycemic response to 4-week low and high glycemic load diets
    Marian Neuhouser; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  43. Monocyte / Macrophage TLR4 Expression and Signaling: A Link between Obesity and C
    Brian McFarlin; Fiscal Year: 2008
    ..The primary purpose of this investigation is to determine if obesity status alters TLR4 signaling and/or inflammatory cytokine production in blood monocyte and adipose tissue macrophage. [unreadable] [unreadable] [unreadable]..
  44. Training Program in Reproductive, Perinatal, and Pediatric Epidemiology
    Anna Maria Siega Riz; Fiscal Year: 2008
    ....
  45. DIETARY DEFICIENCIES AND TUBERCULOSIS VACCINE EFFICACY
    David McMurray; Fiscal Year: 2008
    ..abstract_text> ..
  46. Organochlorine pesticide, PCBs, and Parkinsons
    Alberto Ascherio; Fiscal Year: 2006
    ..Finally, the long follow-up period will allow the investigation of long-term effects of exposure. ..
  47. Prospective Studies of Diet and Cancer in Men and Wonen
    Walter Willett; Fiscal Year: 2006
    ..abstract_text> ..
  48. Breast Cancer Survivors: Physical Activity, Inflammation, Fatigue, and Distress
    Janice Kiecolt Glaser; Fiscal Year: 2007
    ....
  49. Childhood obesity treatment targeting specific behaviors
    Hollie Raynor; Fiscal Year: 2007
    ..Moreover, by comparing the effects of targeting the traditional or substitute behaviors, data will be obtained for a power analysis for a full-scale trial of the effects of these two approaches on long-term weight loss. ..
  50. Prospective Study of Vitamin D and Multiple Sclerosis
    Alberto Ascherio; Fiscal Year: 2010
    ....
  51. LIPOPROTEIN AND ADIPOSE TISSUE METABOLISM IN HIV
    Lars Berglund; Fiscal Year: 2000
    ..abstract_text> ..
  52. EFFECTS OF BUSPIRONE IN WITHDRAWAL FROM OPIATES
    Laure Buydens Branchey; Fiscal Year: 2002
    ..Buspirone has additional advantages. It is not sedating, has no withdrawal symptoms, has no abuse potential, does not potentiate central nervous system depressants and does not induce psychomotor impairment. ..
  53. Diet and Genetic Risks for Prostate Cancer
    Marian Neuhouser; Fiscal Year: 2003
    ..To date, there are 718 confirmed cases of primary prostatic carcinoma. This proposed study will provide important information about prostate cancer etiology and suggest new strategies for prevention and control. ..
  54. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2002
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  55. RISK FACTORS FOR BREAST CANCER AMONG YOUNGER NURSES
    Walter Willett; Fiscal Year: 2000
    ..In addition to the above aims, the NHS II provides the exposure data and initial case identification to examine many other important outcomes among young women. ..
  56. CANCER PREVENTION BY SELENIUM-ENRICHED ALLIUM VEGETABLES
    Clement Ip; Fiscal Year: 2001
    ..The objective is to corroborate the significance of clonal suppression of preneoplastic lesions in selenium protection of cancer. ..
  57. DIET, ENDOTHELIAL FUNCTION AND PEDIATRIC HYPERLIPIDEMIA
    Marguerite Engler; Fiscal Year: 2002
    ..Preventive nursing strategies aimed at early detection of endothelial dysfunction and dietary modification may restore endothelial function in children and adolescents at high risk for CHD. ..
  58. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2004
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  59. IMMUNOSUPPRESSANT MODULATION OF DRUG METABOLISM
    LANE BRUNNER; Fiscal Year: 2001
    ..This information will have direct application to transplant patients and give clinicians needed information regarding the relationship between immunosuppressive therapy and the prediction of toxicity. ..
  60. Role of adipocytes in local and systemic inflammation
    Chantal Rivera; Fiscal Year: 2007
    ....
  61. RETINOIDS, M6P/IGF II RECEPTOR & CELL GROWTH REGULATION
    Jing Kang; Fiscal Year: 2002
    ..This knowledge may lead to novel or more effective therapeutic and preventive approaches for cancer and developmental defects. ..
  62. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2000
    ..Finally, continued studies of fatty acid metabolism in humans, particularly transformations of fatty acids into other bioactive molecules, allows timely evaluation and refinement of developed instruments and methods. ..
  63. Postprandial glycemic response to 4-week low and high glycemic load diets
    Marian Neuhouser; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  64. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William Harris; Fiscal Year: 2008
    ....
  65. Regulation of Lipoprotein(a) Metabolism in Humans with Reference to Ethnicity
    Lars Berglund; Fiscal Year: 2008
    ..The proposal aims to understand which inherited factors affect Lipoprotein(a) and how this factor causes disease. The results will be important to design treatments. ..
  66. EFFECTS OF BUSPIRONE IN WITHDRAWAL FROM OPIATES
    Laure Buydens Branchey; Fiscal Year: 2001
    ..Buspirone has additional advantages. It is not sedating, has no withdrawal symptoms, has no abuse potential, does not potentiate central nervous system depressants and does not induce psychomotor impairment. ..
  67. Monocyte / Macrophage TLR4 Expression and Signaling: A Link between Obesity and C
    Brian McFarlin; Fiscal Year: 2007
    ..The primary purpose of this investigation is to determine if obesity status alters TLR4 signaling and/or inflammatory cytokine production in blood monocyte and adipose tissue macrophage. [unreadable] [unreadable] [unreadable]..
  68. n-3 Fatty Acids Alter T-cell Activation and Signaling
    ROBERT CHAPKIN; Fiscal Year: 2009
    ..Findings from the proposed studies could lead to the development of new therapeutic tools to treat T-cell-mediated inflammation and autoimmunity. ..
  69. n-3 Fatty Acids Alter T-cell Activation and Signaling
    ROBERT STEPHEN CHAPKIN; Fiscal Year: 2010
    ..Findings from the proposed studies could lead to the development of new therapeutic tools to treat T-cell-mediated inflammation and autoimmunity. ..
  70. Sleep deprivation and energy balance
    Marie Pierre St Onge; Fiscal Year: 2010
    ..This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway. ..
  71. The Genetics of Obesity and Diabetes
    Alan D Attie; Fiscal Year: 2010
    ..We shall identify genetic variants of the SorCS1 gene in our two Mexican-American cohorts and test these variants for binding to several ligands and for their ability to promote angiogenesis in vitro. ..
  72. Genes and Gene Networks Associated with Obesity and Diabetes
    Alan D Attie; Fiscal Year: 2010
    ..Our research will help to understand how some, but not all obese people become diabetic and perhaps develop biomarkers to identify individuals at greatest risk for developing diabetes. ..
  73. DIETARY FAT REGULATION OF HEPATIC GENE EXPRESSION
    DONALD JUMP; Fiscal Year: 1993
    ..Finally, it is not unreasonable to expect that the PUFA mechanism of gene control may extend beyond lipogenesis and could explain other metabolic actions of PUFA...
  74. Colonic Cytokinetics and Cell Signaling: Dietary Effects
    ROBERT CHAPKIN; Fiscal Year: 2006
    ..The proposed experiments represent the first attempt to provide an explanation of EPA and DHA action at the molecular level. [unreadable] [unreadable]..
  75. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William Harris; Fiscal Year: 2009
    ....
  76. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 1992
    ..The computer program CONSAAM will be used for biokinetic modeling of fatty acid transport and transformation as components of specific lipid classes in lipoproteins and plasma borne cell types...
  77. Stress and Proinflammatory Cytokines: Omega-3 Intervention
    Janice Kiecolt Glaser; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  78. DIETARY INTERVENTION--WOMEN HIGH RISK FOR BREAST CANCER
    Zora Djuric; Fiscal Year: 2002
    ..The use of biomarkers will allow to evaluate the cancer-protective effects of dietary modulation over a relatively short period of time. ..
  79. Niacin, n-3 fatty acids and insulin resistance
    William Harris; Fiscal Year: 2007
    ..This should lead to more effective therapy for the dyslipidemia of insulin resistance and ultimately to reduced risk for CHD in this burgeoning patient population. ..
  80. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2001
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  81. Genetics of Obesity and Diabetes
    ALAN ATTIE; Fiscal Year: 2005
    ..Identification of obesity and diabetes susceptibility genes will provide clues to novel pathways and biochemical mechanisms underlying complex disease problems. ..
  82. PRECISE ISOTOPE RATIO CHROMATOGRAPHY AND STABLE TRACERS
    JAMES BRENNA; Fiscal Year: 2003
    ..The successful accomplishment of these plans will yield new tools and experimental approaches for investigation of the impact of developmental factors and recent physiological history on development of chronic disease. ..
  83. USE OF ANTIOXIDANT SUPPLEMENTS AND OXIDATIVE DNA DAMAGE
    Marian Neuhouser; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  84. REGULATION OF LIPOPROTEIN (A) METABOLISM IN HUMANS
    Lars Berglund; Fiscal Year: 2003
    ..In addition, the investigators hope that their results with provide a framework for approaches to influence Lp(a) in clinical settings. ..
  85. Regulation of Apolipoprotein B Secretion
    ALAN ATTIE; Fiscal Year: 2006
    ..This will enable us to differentiate between an interaction with apoB early in the secretory pathway and an interaction that occurs after apoB secretion leading to re-uptake of the lipoprotein particles. ..
  86. Genetics of Obesity and Diabetes
    ALAN ATTIE; Fiscal Year: 2004
    ..Identification of obesity and diabetes susceptibility genes will provide clues to novel pathways and biochemical mechanisms underlying complex disease problems. ..
  87. Gas phase derivatization for lipidomic MS analysis
    JAMES BRENNA; Fiscal Year: 2005
    ....
  88. Niacin, n-3 fatty acids and insulin resistance
    William Harris; Fiscal Year: 2005
    ..This should lead to more effective therapy for the dyslipidemia of insulin resistance and ultimately to reduced risk for CHD in this burgeoning patient population. ..
  89. Impact of feeding on brain response to food stimuli in lean and obese subjects
    Marie Pierre St Onge; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  90. Gas phase derivatization for lipidomic MS analysis
    JAMES BRENNA; Fiscal Year: 2004
    ....
  91. The Genetics of Obesity and Diabetes
    ALAN ATTIE; Fiscal Year: 2007
    ..We shall identify genetic variants of the SorCS1 gene in our two Mexican-American cohorts and test these variants for binding to several ligands and for their ability to promote angiogenesis in vitro. ..
  92. Gas phase derivatization for lipidomic MS analysis
    JAMES BRENNA; Fiscal Year: 2007
    ....