organothiophosphorus compounds

Summary

Summary: Compounds containing carbon-phosphorus bonds in which the phosphorus component is also bonded to one or more sulfur atoms. Many of these compounds function as CHOLINERGIC AGENTS and as INSECTICIDES.

Top Publications

  1. ncbi Determining pirimiphos-methyl in durum wheat samples using an acetylcholinesterase inhibition assay
    Michele Del Carlo
    Department of Food Science, University of Teramo, Via Carlo R Lerici 1, Mosciano Stazione, 64023 Teramo, Italy
    Anal Bioanal Chem 381:1367-72. 2005
  2. ncbi Inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds: pig versus minipig acetylcholinesterase
    F Worek
    Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany
    Toxicology 244:35-41. 2008
  3. ncbi The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages
    Matthew Whiteman
    Peninsula Medical School, University of Exeter, St Luke s Campus, Exeter, Devon, England
    Antioxid Redox Signal 12:1147-54. 2010
  4. ncbi Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide
    Ling Li
    Department of Pharmacology, National University of Singapore, Singapore
    Circulation 117:2351-60. 2008
  5. ncbi Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae
    Tamara C Otto
    Physiology and Immunology Branch, Research Division, U S Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010 5400, United States
    Chem Biol Interact 187:388-92. 2010
  6. ncbi Correlating agricultural use of organophosphates with outdoor air concentrations: a particular concern for children
    Martha Harnly
    California Department of Health Services, Oakland, CA 94612, USA
    Environ Health Perspect 113:1184-9. 2005
  7. ncbi Concentrations of dialkyl phosphate metabolites of organophosphorus pesticides in the U.S. population
    Dana B Barr
    National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Environ Health Perspect 112:186-200. 2004
  8. ncbi Experimental and molecular genetic analysis of the impact of pyrethroid and non-pyrethroid insecticide impregnated bednets for mosquito control in an area of pyrethroid resistance
    J H Kolaczinski
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Bull Entomol Res 90:125-32. 2000
  9. ncbi Temporal association of children's pesticide exposure and agricultural spraying: report of a longitudinal biological monitoring study
    Denise Koch
    Department of Environmental Health, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
    Environ Health Perspect 110:829-33. 2002
  10. ncbi Local variation in susceptibility of Colorado potato beetle (Coleoptera: Chrysomelidae) to insecticide
    Ali Asghr Pourmirza
    Department of Entomology, Urmia University, Urmia, Iran
    J Econ Entomol 98:2176-80. 2005

Research Grants

  1. Community-Based Participatory Approach to Farmworker Housing, Exposures & Health
    Thomas A Arcury; Fiscal Year: 2010
  2. Occupational Skin Disease Among Minority Farmworkers
    Thomas Arcury; Fiscal Year: 2007
  3. Differences in CAM Use Among Minority Older Adults
    Thomas Arcury; Fiscal Year: 2005
  4. Farmwoker Environmental Health Research Comparable Data
    Thomas Arcury; Fiscal Year: 2004
  5. LA FAMILIA REDUCING FARMWORKER PESTICIDE EXPOSURE
    Thomas Arcury; Fiscal Year: 2004
  6. Casa A Campo: Pesticide Safety for Farmworkers' Families
    Thomas Arcury; Fiscal Year: 2004
  7. African American Men Prostate & Colorectal Cancer Belief
    Thomas Arcury; Fiscal Year: 2007
  8. Community Participatory Approach to Measuring Farmworker Pesticide Exposures: PAC
    Thomas Arcury; Fiscal Year: 2007
  9. Ethnic Variation in CAM Use and Health Self Management among Rural Older Adults
    Thomas Arcury; Fiscal Year: 2009
  10. Ethnic Variation in CAM Use and Health Self Management among Rural Older Adults
    Thomas Arcury; Fiscal Year: 2009

Detail Information

Publications157 found, 100 shown here

  1. ncbi Determining pirimiphos-methyl in durum wheat samples using an acetylcholinesterase inhibition assay
    Michele Del Carlo
    Department of Food Science, University of Teramo, Via Carlo R Lerici 1, Mosciano Stazione, 64023 Teramo, Italy
    Anal Bioanal Chem 381:1367-72. 2005
    ..The LOD found for the sample, determined under optimal conditions, was 3 mg/kg. Spiked samples were prepared at the EU regulated level (5 mg/kg) and analysed with the optimised protocol, resulting in an average recovery of 70.3%...
  2. ncbi Inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds: pig versus minipig acetylcholinesterase
    F Worek
    Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany
    Toxicology 244:35-41. 2008
    ..The generated data indicate comparable kinetic properties of pig and minipig AChE and may provide a kinetic basis for extrapolation of data from pig studies to humans...
  3. ncbi The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages
    Matthew Whiteman
    Peninsula Medical School, University of Exeter, St Luke s Campus, Exeter, Devon, England
    Antioxid Redox Signal 12:1147-54. 2010
    ..This study may also explain some of the apparent discrepancies in the literature regarding the pro- versus antiinflammatory role of H(2)S...
  4. ncbi Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide
    Ling Li
    Department of Pharmacology, National University of Singapore, Singapore
    Circulation 117:2351-60. 2008
    ....
  5. ncbi Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae
    Tamara C Otto
    Physiology and Immunology Branch, Research Division, U S Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010 5400, United States
    Chem Biol Interact 187:388-92. 2010
    ..Insect production of HuPON1 may provide a source for both in vitro enzymatic and crystallographic studies and in vivo stability and anti-nerve agent efficacy testing...
  6. ncbi Correlating agricultural use of organophosphates with outdoor air concentrations: a particular concern for children
    Martha Harnly
    California Department of Health Services, Oakland, CA 94612, USA
    Environ Health Perspect 113:1184-9. 2005
    ..Agricultural applications of organophosphates and their oxon products may have substantial volatization and off-field movement and are a probable source of exposures of public health concern...
  7. ncbi Concentrations of dialkyl phosphate metabolites of organophosphorus pesticides in the U.S. population
    Dana B Barr
    National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Environ Health Perspect 112:186-200. 2004
    ..These data will be important in evaluating the impact of organophosphorus pesticide exposure in the U.S. population and the effectiveness of regulatory actions...
  8. ncbi Experimental and molecular genetic analysis of the impact of pyrethroid and non-pyrethroid insecticide impregnated bednets for mosquito control in an area of pyrethroid resistance
    J H Kolaczinski
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Bull Entomol Res 90:125-32. 2000
    ....
  9. ncbi Temporal association of children's pesticide exposure and agricultural spraying: report of a longitudinal biological monitoring study
    Denise Koch
    Department of Environmental Health, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
    Environ Health Perspect 110:829-33. 2002
    ....
  10. ncbi Local variation in susceptibility of Colorado potato beetle (Coleoptera: Chrysomelidae) to insecticide
    Ali Asghr Pourmirza
    Department of Entomology, Urmia University, Urmia, Iran
    J Econ Entomol 98:2176-80. 2005
    ..The glass jar and filter paper testing methods are simple and sensitive test techniques for measuring susceptibility of Colorado potato beetle adults and larvae to phosalone, respectively...
  11. ncbi Synergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiae
    Cedric Pennetier
    Institut de Recherche pour le Developpement, Cotonou, Benin
    Malar J 6:38. 2007
    ..The residual efficacy and the inhibition of blood feeding conferred by these mixtures were assessed against Anopheles gambiae mosquitoes...
  12. ncbi Modifications to the organophosphorus nerve agent-protein adduct refluoridation method for retrospective analysis of nerve agent exposures
    Kerry E Holland
    Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    J Anal Toxicol 32:116-24. 2008
    ..5 to 16.5 pg/mL for the G analogue of VX and GD, respectively. Characterization of quality control (QC) materials resulted in an average coefficient of variation of 15.1% for the five analytes in low QC pools and 11.7% in high QC pools...
  13. ncbi Verification of exposure to cholinesterase inhibitors: generic detection of OPCW Schedule 1 nerve agent adducts to human butyrylcholinesterase
    M J van der Schans
    TNO Defence, Security, and Safety, PO Box 45, 2280 AA Rijswijk, The Netherlands
    J Anal Toxicol 32:125-30. 2008
    ..A method for which only 34 transitions in the multiple reaction monitoring mode have to be acquired in order to screen for an exposure to all Organization for the Prohibition of Chemical Weapons Schedule 1 nerve agents was developed...
  14. ncbi Monitoring of insecticide residues in cotton seed in Punjab, India
    B Blossom
    Department of Entomology, Punjab Agricultural University, Ludhiana 141004, India
    Bull Environ Contam Toxicol 73:707-12. 2004
  15. ncbi Evaluation of potency of known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to in vitro reactivate acetylcholinesterase inhibited by pesticides (chlorpyrifos and methylchlorpyrifos) and nerve agent (Russian VX)
    Kamil Musilek
    University of Defence, Faculty of Military Health Sciences, Department of Toxicology, Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 50:203-6. 2007
    ..Especially, methylchlorpyrifos-inhibited AChE was found to be poorly reactivated by the compounds used...
  16. ncbi [Effect of organophosphorous insecticides on Chinese chive insect pests and their degradation by pesticide-degrading bacterium]
    Jiandong Jiang
    Key Laboratory of Microbiological Engineering of Agricultural Environment, Ministry of Agriculture, College of Life Sciences, Nanjing Agricultural University, China
    Ying Yong Sheng Tai Xue Bao 15:1459-62. 2004
    ..52% and 98.83%, and at the 3rd after spraying 75.00 L x hm(-2) pesticide-degrading bacterium to control Bradysia odoriphaga, the degradation rate of three concentrations of phoxin was 100%, 100% and 99.69%, respectively...
  17. ncbi Percutaneous penetration and distribution of VX using in vitro pig or human excised skin validation of demeton-S-methyl as adequate simulant for VX skin permeation investigations
    V Vallet
    Department of Toxicology, Centre de Recherche du Service de Sante des Armees, 38702 La Tronche Cedex, France
    Toxicology 246:73-82. 2008
    ....
  18. ncbi Monitoring exposure of passerines to acephate, dicrotophos, and malathion using cholinesterase reactivation
    J D Maul
    Ecotoxicology Research Facility, Environmental Sciences Program, Post Office Box 847, Arkansas State University, State University, AR 72467, USA
    Bull Environ Contam Toxicol 73:682-9. 2004
  19. ncbi Biochemical monitoring of acetylcholinesterase sensitivity to organophosphorus insecticides in glassy-winged sharpshooter Homalodisca coagulata Say (Homoptera: Cicadellidae) and smoke-tree sharpshooter H. lacerta Fowler
    Frank J Byrne
    Department of Entomology, University of California, Riverside, CA 92521, USA
    J Econ Entomol 96:1849-54. 2003
    ..This species is native to California and is regarded only as a minor pest. Both inhibition and kinetic measurements for the AChE enzymes in these sharpshooters demonstrate the close phylogenetic relationships between the two species...
  20. ncbi Cumulative risk assessment of the exposure to organophosphorus and carbamate insecticides in the Dutch diet
    P E Boon
    RIKILT Institute of Food Safety, Wageningen University and Research Centre, AE Wageningen, The Netherlands
    Food Chem Toxicol 46:3090-8. 2008
    ..Spinach contributed most to the exposure to OPs in both age groups, followed by orange and mandarin. For carbamates apple (sauce) was the main product determining the exposure...
  21. ncbi Physicochemical and biological data for the development of predictive organophosphorus pesticide QSARs and PBPK/PD models for human risk assessment
    James B Knaak
    Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, SUNY at Buffalo, Buffalo, New York 14214, USA
    Crit Rev Toxicol 34:143-207. 2004
    ..A program is needed to require the development of physicochemical and biological data to support risk assessment methodologies involving QSAR and PBPK/PD models...
  22. ncbi Effects of different factors on the residues of heptenophos in cucumber
    K Talebi
    Dept. of Plant Protection, College of Agriculture, University of Tehran, Karaj, Iran
    Commun Agric Appl Biol Sci 68:789-93. 2003
    ..2 and 0.1 mg/kg respectively). Two times application of heptenophos caused no insecticide accumulation in cucumber. This investigation revealed that peeling the fruits did not reduce total residues in cucumber...
  23. ncbi A comparative study on the relationship between acetylcholinesterase activity and acute toxicity in Daphnia magna exposed to anticholinesterase insecticides
    Liane Biehl Printes
    Division of Zoology, School of Animal and Microbial Sciences, University of Reading, Whiteknights, P.O. Box 228, Reading, Berkshire RG6 6AJ, United Kingdom
    Environ Toxicol Chem 23:1241-7. 2004
    ..Our findings demonstrate different associations between AChE inhibition and toxicity when different chemicals are compared. Therefore, the value of using AChE activity as a biomarker in D. magna will be dependent on the chemical tested...
  24. ncbi Distribution and toxicity of sediment-associated pesticides in agriculture-dominated water bodies of California's Central Valley
    D P Weston
    Department of Integrative Biology, University of California, 3060 Valley Life Sciences Building, Berkeley, California 94720 3140, USA
    Environ Sci Technol 38:2752-9. 2004
    ....
  25. ncbi Chromosomal aberrations in human lymphocytes exposed to the anticholinesterase pesticide isofenphos with mechanisms of leukemogenesis
    Robert D Williams
    CFE Toxicology, LLC, P O Box 275, Lewis Center, OH 43035 0275, USA
    Leuk Res 28:947-58. 2004
    ....
  26. ncbi [Susceptibility and related physiological and biochemical mechanisms of Carposina niponensis Walsingham larvae on six insecticides before and after overwintering]
    Yue Liang Zhang
    College of Plant Protection, Shandong Agricultural University, Tai an 271018, Shandong, China
    Ying Yong Sheng Tai Xue Bao 18:1913-6. 2007
    ..It was suggested that the difference of the susceptibility was resulted from the changes in the contents of biochemical substances and the activities of metabolic enzymes, protective enzymes and target enzyme...
  27. ncbi [Susceptibility and insecticide resistance mechanisms in Anopheles albimanus from the southern Yucatan Peninsula, Mexico]
    Felipe A Dzul
    Centro de Investigacion de Paludismo, Instituto Nacional de Salud Publica, Tapachula, Chiapas, Mexico
    Salud Publica Mex 49:302-11. 2007
    ..To diagnose susceptibility levels and insecticide resistance mechanisms in Anopheles albimanus from the southern Yucatan Peninsula (YP), Mexico...
  28. ncbi Estimation of apoptosis and necrosis caused by pesticides in vitro on human lymphocytes using DNA diffusion assay
    G Prabhavathy Das
    Genetics Department, Bhagwan Mahavir Medical Research Centre, A.C. Guards, Hyderabad, Andhra Pradesh, India
    Drug Chem Toxicol 29:147-56. 2006
    ..The results are statistically significant (p < 0.001). Data on these alterations of immune cells are required for understanding the subchronic effects mediated by pesticides on nontarget organisms...
  29. ncbi Evaluation of reactivation test in anaesthetized dogs with experimental intoxication with nerve agents
    J Bajgar
    Department of Toxicology, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
    J Appl Toxicol 26:439-43. 2006
    ..Thus, the reactivation efficacy of obidoxime during nerve agent intoxication indicates that its repeated administration could be easily monitored using the reactivation test...
  30. ncbi Determination of acephate in human urine
    Jane T LePage
    Washington State University, Food and Environmental Quality Laboratory, 2710 University Dr, Richland, WA 99354, USA
    J AOAC Int 88:1788-92. 2005
    ..The method limit of detection was established at 2 microg/L, with a method limit of quantitation of 10 microg/L. The average recovery from urine fortified with 10-500 microg/L was 102 +/- 12% (n = 32)...
  31. ncbi Variability of organophosphorus insecticide residues in large size crops grown in commercial farms in Brazil
    Eloisa Caldas
    College of Health Sciences, University of Brasilia, DF, Brazil
    Food Addit Contam 23:148-58. 2006
    ..The results found in this study support the variability factor of 3 adopted by the FAO/WHO for the deterministic estimation of dietary acute intake of pesticides...
  32. ncbi The reactivating and therapeutic efficacy of oximes to counteract Russian VX poisonings
    Jiri Kassa
    Department of Toxicology, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
    Int J Toxicol 25:397-401. 2006
    ..Thus, the oxime HI-6 seems to be the most suitable oxime for the antidotal treatment of acute poisonings with Russian VX as in the case of VX, sarin, cyclosarin, and soman poisonings...
  33. ncbi Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro
    Kamil Kuca
    Department of Toxicology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Drug Chem Toxicol 30:31-40. 2007
    ..Moreover, oxime HI-6 (the most effective one) was not able to reactivate tabun- and soman-inhibited AChE. Due to this fact, it could be designated as a partially broad-spectrum reactivator...
  34. ncbi Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro
    F Worek
    Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany
    J Appl Toxicol 27:582-8. 2007
    ..By using different oxime concentrations a combination of oxime doses may be suggested which could be an alternative to individual obidoxime or HI 6 autoinjectors...
  35. ncbi Soil dehydrogenase, phosphomonoesterase and arginine deaminase activities in an insecticide treated groundnut (Arachis hypogaea L.) field
    Sushma Pandey
    Department of Zoology, University of Delhi, Delhi-110 007, India
    Chemosphere 63:869-80. 2006
    ..It was observed that in most of cases insecticides have temporary inhibitory effect on soil enzymes. However, inhibition was smaller in seed treated soil than in direct soil treatment...
  36. ncbi Effects of of habitats and pesticides on aerobic capacity and survival of soil fauna
    G Tripathi
    Department of Zoology, J N Vyas University, Jodhpur 342 001, India
    Biomed Environ Sci 18:169-75. 2005
    ..Faunal health is largely dependent on their soil environment and available litter quality. So the effects of different soil habitats and pesticides on citrate synthase (CS) activity of soil fauna and its population were studied...
  37. ncbi Recoveries of four representative organophosphorus pesticides from 18 plant products belonging to different botanical categories: implications for matrix effects
    P Georgakopoulos
    Agricultural University of Athens, Department of Food Science and Technology, Laboratory of Food Hygiene and Quality Control, Athens, Greece
    Food Addit Contam 24:360-8. 2007
    ....
  38. ncbi Unequal efficacy of pyridinium oximes in acute organophosphate poisoning
    Biljana Antonijevic
    Institute of Toxicological Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia
    Clin Med Res 5:71-82. 2007
    ..Since there are no reports of controlled clinical trials on the use of TMB-4 in human organophosphate pesticide poisoning, LüH-6 may be a better option...
  39. ncbi Contamination of vegetables of different seasons with organophosphorous pesticides and related health risk assessment in northern India
    Mayank Bhanti
    School of Chemical Sciences, Department of Chemistry, St John s College, Agra, UP 282002, India
    Chemosphere 69:63-8. 2007
    ..The analysis of health risk estimates indicated that chlorpyriphos and malathion did not poses a direct hazard, however, exposure to methyl parathion has been found to pose some risk to human health...
  40. ncbi Extremely sensitive biomarker of acute organophosphorus insecticide exposure
    Yasuhiro Fujikawa
    Drug Safety Research Laboratories, Eisai Co Ltd, Ibaraki, Japan
    Hum Exp Toxicol 24:333-6. 2005
    ..The increase in plasma BG activity after OP exposure is a much more sensitive biomarker of acute OP exposure than acetylcholinesterase (AChE) inhibition...
  41. ncbi Morphometric studies of cardiac myocytes of rats chronically treated with an organophosphate
    E E Calore
    Pathology Section, Emilio Ribas Institute, Sao Paulo, Brazil
    Ecotoxicol Environ Saf 66:447-50. 2007
    ..One of the possible explanations for the cardiac hypertrophy would be persistent systemic arterial hypertension in treated animals. However, another possible explanation would be direct sympathetic stimulation...
  42. ncbi Enantioselective acetylcholinesterase inhibition of the organophosphorous insecticides profenofos, fonofos, and crotoxyphos
    Mae Grace Nillos
    Environmental Toxicology Program, University of California, CA 92521, USA
    Environ Toxicol Chem 26:1949-54. 2007
    ....
  43. ncbi In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase
    Kamil Kuca
    Department of Toxicology, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic
    J Toxicol Environ Health A 69:1431-40. 2006
    ..More than one oxime may be necessary for the antidotal treatment of nerve agent-exposed individuals...
  44. ncbi Capillary gas chromatographic analysis of nerve agents using large volume injections
    C E Degenhardt-Langelaan
    TNO Prins Maurits Laboratory, Rijswijk, The Netherlands
    J Chromatogr A 723:210-4. 1996
    ..Except for the nerve agent tabun all other agents added to the water samples were still present after 8 days at 20-60% levels, if the pH of the water sample is adjusted to ca. 5 shortly after sampling and adjusted to pH 7 for analysis...
  45. ncbi Activated transformations of organophosphorus insecticides in the case of non-AChE inhibitory oxons
    Takeo Kasagami
    Department of Applied Biology and Chemistry, Tokyo University of Agriculture, Tokyo 156 8502, Japan
    Pest Manag Sci 58:1107-17. 2002
    ....
  46. ncbi Immunotoxicity of acute acephate exposure in control or IL-1-challenged rats: correlation between the immune cell composition and corticosteroid concentration in blood
    Ashok K Singh
    Department of Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, St Paul Campus, St Paul, MN 55180, USA
    J Appl Toxicol 22:279-91. 2002
    ....
  47. ncbi Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates
    F Worek
    Sanitätsakademie der Bundeswehr, Institut fur Pharmakologie und Toxikologie, Neuherbergstrasse 11, 80937 Munich, Germany
    Arch Toxicol 76:523-9. 2002
    ..The results show marked differences among the species, depending on the inhibitor and on the oxime, and indicate that the findings from animal experiments need careful evaluation before extrapolating these data to humans...
  48. ncbi Biological monitoring of combined exposure to organophosphates and pyrethroids
    Fengsheng He
    Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing, People s Republic of China
    Toxicol Lett 134:119-24. 2002
    ..In addition to the fact that the OP is more potent than Pyrs, the above results might explain why the clinical manifestations of OP mixture poisonings are similar to those of single OP poisoning...
  49. ncbi Cleanup of gloves contaminated with granular terbufos and tefluthrin
    C Guo
    Ansell Healthcare Products Inc, 1875 Harsh Avenue SE, Massillon, Ohio 44648-0550, USA
    Arch Environ Contam Toxicol 42:383-8. 2002
    ..Barrier laminate was confirmed as a single-use material. Cleanup procedures reduced contamination in nitrile and neoprene, but findings show that these materials retained residue after cleanup...
  50. ncbi The relationship between isofenphos cholinergic toxicity and the development of polyneuropathy in hens and humans
    Angelo Moretto
    Dipartimento di Medicina Ambientale e Sanità Pubblica, Universita degli Studi di Padova, Via Giustiniani 2, 35128 Padova, Italy
    Arch Toxicol 76:367-75. 2002
    ..o.), the birds remained asymptomatic. Since other organophosphates may have a prolonged pharmacokinetics, testing procedures for the potential of these insecticides to cause OPIDP may underestimate the risk for humans...
  51. ncbi Rapid detection of neurotoxic insecticides in food using disposable acetyicholinesterase-biosensors and simple solvent extraction
    Holger Schulze
    Institute of Technical Biochemistry, University of Stuttgart, Germany
    Anal Bioanal Chem 372:268-72. 2002
    ..The assay displayed a detection limit of 2 microg/kg paraoxon, which was sufficient for the monitoring of maximum residue limits in food according to EU regulations...
  52. ncbi Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
    Huibert D Mansvelder
    Department of Anesthesia, University of Chicago, Chicago, IL 60637, USA
    Neuron 33:905-19. 2002
    ..These results suggest that spatial and temporal differences in nicotinic receptor activity on both excitatory and inhibitory neurons in reward areas coordinate to reinforce nicotine self-administration...
  53. ncbi Persistence and retention of active ingredients in four granular cholinesterase-inhibiting insecticides in agricultural soils of the lower Fraser River valley, British Columbia, Canada, with implications for wildlife poisoning
    Laurie K Wilson
    Canadian Wildlife Service, Pacific Wildlife Research Centre, RRI Delta, British Columbia
    Environ Toxicol Chem 21:260-8. 2002
    ..The risk of acute poisoning by phorate and fonofos continued though the winter...
  54. ncbi Toxicological studies of organophosphate and pyrethroid insecticides for controlling the fruit fly Dacus ciliatus (Diptera: Tephritidae)
    A Maklakov
    Department of Entomology, Institute for Plant Protection, Agricultural Research Organization, The Volcani Center, Bet Dagan, Israel
    J Econ Entomol 94:1059-66. 2001
    ..ciliatus. It can be concluded that pyrethroids have high potential for controlling D. ciliatus...
  55. ncbi Sex-related differences in the tolerance of Oriental fruit moth (Grapholita molesta) to organophosphate insecticides
    F M de Lame
    Department of Entomology, Rutgers, The State University of New Jersey, Blake Hall, 93 Lipman Drive, New Brunswick, NJ 08901, USA
    Pest Manag Sci 57:827-32. 2001
    ..The practical implications of the observed differences in tolerance in male and female G molesta question the practice of using pheromone traps to monitor populations of these moths in orchards...
  56. ncbi Resolving pathways of interaction of covalent inhibitors with the active site of acetylcholinesterases: MALDI-TOF/MS analysis of various nerve agent phosphyl adducts
    E Elhanany
    Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 74100, Israel
    Chem Res Toxicol 14:912-8. 2001
    ..For methamidophos, we show that phosphylation of AChE involves elimination of the thiomethyl moiety and that the spontaneous reactivation of the resulting organophosphate adduct generates the phosphorus free AChE active site Ser-peptide...
  57. ncbi Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides
    G B Quistad
    Environmental Chemistry and Toxicology Laboratory, Department of Environmental Science, Policy and Management, University of California, 114 Wellman Hall, Berkeley, California, 94720-3112, USA
    Toxicol Appl Pharmacol 173:48-55. 2001
    ..More generally, OP compound-induced FAAH inhibition and the associated anandamide accumulation may lead to reduced limb mobility as a secondary neurotoxic effect...
  58. ncbi Degradation of atrazine and several organophosphorus pesticides in oranges
    A Bouaid
    , , Universidad Complutense de Madrid, 28040 Madrid, Spain
    Ann Chim 91:93-102. 2001
    ..1 days and 14.2 days, respectively. The presence of some organophosphorus degradation products in water samples after storage under the above conditions was confirmed by gas chromatography-mass spectrometry...
  59. ncbi Comparative inhibition kinetics for acetylcholinesterases extracted from organophosphate resistant and susceptible strains of Boophilus microplus (Acari: Ixodidae)
    John H Pruett
    Knipling Bushland US Livestock Insects Research Laboratory, USDA ARS SPA, Kerrville, TX 78028, USA
    J Econ Entomol 95:1239-44. 2002
    ..The bimolecular reaction constants (ki) of the resistant strains were most affected by a slower rate of enzyme phosphorylation (k2)...
  60. ncbi Occupational exposure to cholinesterase inhibiting pesticides: a Greek case
    M Stefanidou
    Department of Forensic Medicine and Toxicology, Medical School, University of Athens, Goudi, Greece
    Int J Environ Health Res 13:23-9. 2003
    ..The results of this study showed a plasma cholinesterase depression of 37%, a decrease which was statistically significant (P<0.001)...
  61. ncbi [Stimulation single fiber electromyography in rats with myasthenia induced by organophosphorus insecticides and their mixtures poisoning]
    Cheng Xiao
    Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing 100050, China
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 20:125-7. 2002
    ..The SSFEMG with stimulus frequency at 10 Hz or 20 Hz could be used to detect the neuromuscular dysfunction during myasthenia induced by organophosphate insecticides and their mixtures poisoning...
  62. ncbi [The activity of blood cholinesterase in rats exposed to dimehypo]
    Weiguo Wan
    Occupational Department, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 20:416-8. 2002
    ..01). CONCLUSION: Higher doses of dimehypo may inhibit the activity of ChE. However, as compared with methamidophos, dimehypo is a weaker inhibitor of ChE...
  63. ncbi Donepezil modulates nicotinic receptors of substantia nigra dopaminergic neurones
    Silvia Di Angelantonio
    Laboratorio di Neurologia Sperimentale, IRCCS Fondazione Santa Lucia, Via Ardeatina 306, Rome 00179, Italy
    Br J Pharmacol 141:644-52. 2004
    ..5. Pretreatment with vesamicol or methamidophos did not prevent the reduction of nicotine-induced currents. The data indicated direct effect on nAChR, independent from the activity of donepezil as cholinesterase inhibitor...
  64. ncbi Nerve agents: implications for anesthesia providers
    Paula Kay Hrobak
    University of Pittsburgh, School of Nursing, Nurse Anesthesia Program, PA, USA
    AANA J 76:95-7. 2008
    ..This article also reviews the physiology of the neuromuscular junction and the autonomic nervous system receptors that nerve agent toxicity affects...
  65. ncbi A structure-activity analysis of the variation in oxime efficacy against nerve agents
    Donald M Maxwell
    US Army Medical Research Institute of Chemical Defense, Research Division, Pharmacology Branch, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010 5400, USA
    Toxicol Appl Pharmacol 231:157-64. 2008
    ....
  66. ncbi Gender difference in the miotic potency of soman vapor in rats
    Paul A Dabisch
    Operational Toxicology Team, U S Army Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010 5424, USA
    Cutan Ocul Toxicol 27:123-33. 2008
    ..The results also demonstrate that ocular acetylcholinesterase and butyrylcholinesterase activities differ between males and females, although this difference is not likely large enough to account for the observed gender difference...
  67. ncbi Oxydemeton-methyl resistance, mechanisms, and associated fitness cost in green peach aphids (Hemiptera: Aphididae)
    M Ghadamyari
    Department of Plant Protection, Faculty of Agriculture, University of Guilan, Rasht, Iran
    J Econ Entomol 101:1432-8. 2008
    ..These results suggested that the resistant Karaj strain may be less fit than the susceptible strain...
  68. ncbi Oxidases responsible for resistance to pyrethroids sensitize Helicoverpa armigera (Hübner) to triazophos in West Africa
    Thibaud Martin
    CIRAD CA, 34398 Montpellier, France
    Insect Biochem Mol Biol 33:883-7. 2003
    ..This suggests that oxidases, which provide resistance by degradation of pyrethroids in the resistant individuals, also activate triazophos in its toxic oxon form resulting in a negative cross-resistance...
  69. ncbi Dissipation of quinalphos in kinnow mandarin fruits under subtropical conditions of Punjab, India
    Raminderjit S Battu
    Department of Entomology, Pesticide Residue Analysis Laboratory, Punjab Agricultural University, Ludhiana 141004, India
    Bull Environ Contam Toxicol 80:395-8. 2008
    ..The results clearly show that quanilphos does not penetrate into the pulp of the kinnow mandarin and the fruit is safe for consumption even after one day of the application at both these dosages...
  70. ncbi Comparison of C18 silica and multi-walled carbon nanotubes as the adsorbents for the solid-phase extraction of Chlorpyrifos and Phosalone in water samples using HPLC
    Mohammad Reza Hadjmohammadi
    Department of Chemistry, University of Mazandaran, Babolsar, Iran
    J Sep Sci 33:1044-51. 2010
    ..00 microg/mL and 2.3% for Phosalone, in C(18) cartridge, respectively. These values for MWCNT were 4.02x10(-6), 0.001-0.500 microg/mL and 1.8% for Chlorpyrifos and 1.02x10(-6), 0.001-0.500 microg/mL and 1.5% for Phosalone, respectively...
  71. ncbi Phosphotriesterase variants with high methylphosphonatase activity and strong negative trade-off against phosphotriesters
    Luis Briseño-Roa
    MRC Centre for Protein Engineering, Hills Road, Cambridge CB20QH, UK
    Protein Eng Des Sel 24:151-9. 2011
    ....
  72. ncbi Comparison of polyethylene glycol-conjugated recombinant human acetylcholinesterase and serum human butyrylcholinesterase as bioscavengers of organophosphate compounds
    Ofer Cohen
    Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel
    Mol Pharmacol 70:1121-31. 2006
    ..3-1.5 LD50). These findings together with the observations that the PEGylated rHuAChE exhibits unaltered biodistribution and high bioavailability present a case for using PEGylated rHuAChE as a very efficacious bioscavenger of OP agents...
  73. ncbi Propetamphos-induced changes in haematological and biochemical parameters of female rats: protective role of propolis
    Ebru Cetin
    Department of Physiology, Faculty of Veterinary Medicine, University of Erciyes, Kayseri, Turkey
    Food Chem Toxicol 48:1806-10. 2010
    ..In conclusion, propetamphos was determined to cause harmful effects in rats, and the administration of propolis to these animals alleviated the harmful effects of propetamphos...
  74. ncbi Separation and aquatic toxicity of enantiomers of the organophosphorus insecticide trichloronate
    Weiping Liu
    Research Center of Green Chirality, Zhejiang University of Technology, Hangzhou, People s Republic of China
    Chirality 18:713-6. 2006
    ..These results suggest that assessment of the environmental safety of chiral OPs should take stereospecificity into consideration...
  75. ncbi Controlled release formulations of acephate: water and soil release kinetics
    Keyath Nisar
    Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi, India
    J Environ Sci Health B 44:533-7. 2009
    ..33 to 36.34 and 12.49 to 29.09 days respectively. The results suggest that depending upon the polymer matrix used, the application rate of acephate can be optimized to achieve insect control at the desired level and period...
  76. ncbi Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for detection and identification of albumin phosphylation by organophosphorus pesticides and G- and V-type nerve agents
    Harald John
    Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany
    Anal Bioanal Chem 398:2677-91. 2010
    ..In conclusion, the current analytical design exhibits potential as a verification tool for high-dose exposure...
  77. ncbi Evaluation of HI 6 treatment after percutaneous VR exposure by use of a kinetic-based dynamic computer model
    N Aurbek
    Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany
    Toxicology 233:173-9. 2007
    ....
  78. ncbi Efficient heterogeneous and environmentally friendly degradation of nerve agents on a tungsten-based POM
    Dana M Mizrahi
    Department of Organic Chemistry, Israel Institute for Biological Research, P O Box 19, Ness Ziona 74100, Israel
    J Hazard Mater 179:495-9. 2010
    ..Mustard gas (HD), whose degradation is highly dependent on oxidation, was not decontaminated by this POM. Solid state MAS NMR ((31)P and (13)C) was utilized both for POM characterization and for decontamination studies monitoring...
  79. ncbi VX-induced cell death involves activation of caspase-3 in cultured rat cortical neurons
    Catherine C Tenn
    Medical Therapy Group, DRDC Suffield, P O Box 4000, Station Main, Medicine Hat, Alberta T1A 8K6, Canada
    Neurosci Lett 417:155-9. 2007
    ..These data suggested that in rat cortical neurons, VX-induced cell death via a programmed cell death pathway that involves changes in caspase-3 protease...
  80. ncbi Reversed micelle formation in a model liquid-liquid extraction system
    Fuqiang Guo
    Key Laboratory of Rare Earth on Advanced Materials and Valuable Utilization of Resources, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
    J Colloid Interface Sci 322:605-10. 2008
    ..The extractant and extracted complexes, such as Cyanex923H(2)SO(4), were involved in the formation of reversed micelles...
  81. ncbi Numerical variations and spontaneous malformations in the early embryos of the Korean salamander, Hynobius leechii, in the farmlands of Korea
    Yong Uk Park
    Department of Biology, College of Natural Sciences, Changwon National University, Changwon, Gyeongnam 641 773, Korea
    Environ Toxicol 25:533-44. 2010
    ..These results indicate that various agricultural chemicals and other unknown factors may cause the aforementioned forms of spontaneous malformations in the embryos of Hynobius leechii...
  82. ncbi Protective effect of reversible cholinesterase inhibitors (tacrine, pyridostigmine) and eqbuche against VX poisoning and brain acetylcholinesterase inhibition in rats
    Jiri Bajgar
    University of Defence, Faculty of Military Health Sciences, Department of Toxicology, Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 51:223-8. 2008
    ..Tacrine alone or in other combinations has had no better prophylactic effect in comparison with these combinations containing pyridostigmine. Equine butyrylcholinesterase, also protected against VX poisoning very effectively...
  83. ncbi Facile hydrolysis-based chemical destruction of the warfare agents VX, GB, and HD by alumina-supported fluoride reagents
    E Gershonov
    The Department of Organic Chemistry, Israel Institute for Biological Research, Ness Ziona 74100, Israel
    J Org Chem 74:329-38. 2009
    ..The mechanisms and the efficiency of these processes were successfully studied by solid-state (31)P, (13)C, and (19)F MAS NMR...
  84. ncbi Compatibility of Verticillium lecani (Zimm.) with several pesticides
    A Alizadeh
    College of Agriculture, Vali E Asr University, Rafsanjan, Iran
    Commun Agric Appl Biol Sci 72:1011-5. 2007
    ..lecanii. These formulations could be used simultaneously with this entomopathogenic in integrated pest management...
  85. ncbi Kinetics and thermodynamics of adsorption of cadusafos on soils
    Gamal S ElShafei
    Chem Dpt, Fac of Sci, Ain Shams University, Abbassia, Cairo, Egypt
    J Hazard Mater 172:1608-16. 2009
    ..The intraparticles diffusion is of lower significance in case of sandy soil than in clay soil. Thermodynamic parameters indicated that the adsorption is spontaneous, endothermic accompanied by increase in entropy...
  86. ncbi [Effects of methamidophos and 17beta-estradiol on the dynamics of experimental population of freshwater rotifer Brachionus calyciflorus]
    Li xia Ke
    Provincial Key Laboratory of Conservation and Utilization for Important Biological Resource in Anhui, College of Life Science, Anhui Normal University, Wuhu, Anhui, China
    Ying Yong Sheng Tai Xue Bao 19:157-62. 2008
    ..002X + 0.374. The population growth rate could be used to assess the effects of methamidophos on the population dynamics of the rotifer...
  87. ncbi Distribution of dimethoate in the body after a fatal organophosphate intoxication
    F A Tarbah
    Dubai Police H Q, Forensic Science Department, Dubai, United Arab Emirates
    Forensic Sci Int 170:129-32. 2007
    ..Blood alcohol was 2.85 g/L, cyclohexanone and cyclohexanol were also detected in the blood but not quantified. The cause of death was determined as organophosphate intoxication...
  88. ncbi Synthesis of phosphorothioate oligonucleotides with stereodefined phosphorothioate linkages
    Piotr Guga
    Polish Academy of Sciences, Lodz, Poland
    Curr Protoc Nucleic Acid Chem . 2003
    ....
  89. ncbi Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats
    Raymond F Genovese
    Divisions of Psychiatry and Neurosciences, Walter Reed Army Institute of Research, Silver Spring, MD 20910 7500, USA
    Basic Clin Pharmacol Toxicol 106:428-34. 2010
    ..These results add to the safety assessment of Hu BChE as a bioscavenger countermeasure against nerve agent exposure...
  90. ncbi Evaluation of comprehensive two-dimensional gas chromatography - time-of-flight mass spectrometry for the determination of pesticides in tobacco
    Jack Cochran
    Restek Corporation, 110 Benner Circle, Bellefonte, PA 16823, USA
    J Chromatogr A 1186:202-10. 2008
    ..5 to 50 ng/mL concentrations of numerous organochlorine and organophosphorus pesticides were used to demonstrate linearity and the GC x GC benefit of eliminating interferences that might contribute to quantification bias...
  91. ncbi Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study
    Matthew R Bonner
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, 270 Farber Hall, Buffalo, NY, USA
    Cancer Causes Control 21:871-7. 2010
    ..We investigated associations between use of terbufos and the incidence of cancer...
  92. ncbi Selective extraction of zinc(II) over iron(II) from spent hydrochloric acid pickling effluents by liquid-liquid extraction
    Marcelo Borges Mansur
    Department Engenharia Metalúrgica e de Materiais, Universidade Federal de Minas Gerais, Rua Espirito Santo, 35, 2 andar, Centro, 30130 090 Belo Horizonte, MG, Brazil
    J Hazard Mater 150:669-78. 2008
    ..4. Cyanex 302 presented low metal extraction levels (below 10%) and slow phase disengagement characteristics. Reactions for the extraction of zinc with TBP and Cyanex 301 from hydrochloric acid solution were proposed...
  93. ncbi Effect of methamidophos and urea application on microbial communities in soils as determined by microbial biomass and community level physiological profiles
    Meng-Cheng Wang
    State Key Laboratory of Pharmaceutical Biotechnology, Plant Cell and Molecular Biology Laboratory, Department of Biological Science and Technology, School of Life Science, Nanjing University, Nanjing, P.R. China
    J Environ Sci Health B 41:399-413. 2006
    ..The combined results suggest that agrochemicals reduce microbial biomass and enhance functional diversities of soil microbial communities; meanwhile, some species of bacteria may be enriched in soils under methamidophos stress...
  94. ncbi Delivery across the blood-brain barrier of antisense directed against amyloid beta: reversal of learning and memory deficits in mice overexpressing amyloid precursor protein
    W A Banks
    Geriatric Research, Education and Clinical Center, St. Louis Veterans Affairs Medical Center and Department of Internal Medicine, Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, USA
    J Pharmacol Exp Ther 297:1113-21. 2001
    ..c.v. dose reversed the learning and memory deficits of aged SAMP8 mice. These studies show for the first time that phosphorothiolate oligonucleotides can be delivered to the brain in effective doses by intravenous administration...
  95. ncbi Evaluation of biological and chemical insecticide mixture against Aedes aegypti larvae and adults by thermal fogging in Singapore
    Y K Chung
    Vector Control and Research Department, Ministry of the Environment, Singapore
    Med Vet Entomol 15:321-7. 2001
    ..Results demonstrate the practical advantage of using this mixture of Vectobac 12AS and Actellic 50 EC for simultaneous control of Aedes adults and larvae, with prolonged larvicidal efficacy in treated containers...
  96. ncbi Bioavailability and biological activity of bound residues of radiolabelled pirimiphos-methyl in maize grains
    P O Yeboah
    Department of Chemistry, National Nuclear Research Institute, Ghana Atomic Energy Commission, Legon
    J Environ Sci Health B 27:377-86. 1992
    ..No significant changes were observed in the other blood chemistry parameters tested. The results indicate that maize-bound pirimiphos-methyl residues can exert adverse biological effects in the rat...
  97. ncbi The mineralisation of methamidophos using ionised AN air water treatment pilot system and ultraviolet irradiation
    Dang Quang Hung
    Department of Chemistry, AG Thiemann, Institute of Physical and Environmental Chemistry, University of Bremen, Germany
    Water Res 36:2959-66. 2002
    ..The toxicity of water samples before, during and after the experiments was tested with Daphnia test...
  98. ncbi Enzymatic hydrolysis of Russian-VX by organophosphorus hydrolase
    V K Rastogi
    Geo Centers, Inc ERDEC, Aberdeen Proving Ground, Maryland 21010, USA
    Biochem Biophys Res Commun 241:294-6. 1997
    ..5% ethanol, isoamyl-alcohol, or isopropanol. The presence of acetonitrile, diethylene glycol, or methanol had marginal effects. These results comprise the first demonstration of enzymatic detoxification of R-VX...
  99. ncbi Effects of a novel organophosphorus pesticide (RPR-V) on extra hepatic detoxifying enzymes after repeated oral doses in rats
    Mohammed Mahboob
    Analytical Toxicology Division, Industrial Toxicological Research Center, Mahatma Gandhi Marg, P O Box 80, Lucknow 226001, India
    Toxicology 202:159-64. 2004
    ..These results suggest that RPR-V has the potential to modulate the extrahepatic detoxifying enzymes and thereby interact with other physiological processes in the exposed organisms...
  100. ncbi Seasonal changes of methamidophos susceptibility and biochemical properties in Plutella xylostella (Lepidoptera: Yponomeutidae) and its parasitoid Cotesia plutellae (Hymenoptera: Braconidae)
    Gang Wu
    Department of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China 35000
    J Econ Entomol 97:1689-98. 2004
    ..From these results, a spatial and temporal correlative evolution of methamidophos resistance and insensitive AChE was found to exist between P. xylostella and C. plutellae...
  101. ncbi Influence of two insecticides, chlorpyrifos and quinalphos, on arginine ammonification and mineralizable nitrogen in two tropical soil types
    Pramila Menon
    Department of Zoology, University of Delhi, Delhi 7, India
    J Agric Food Chem 52:7370-6. 2004
    ..They also caused no long-term inhibition of ammonification, which could have been of significant concern during the short crop period in semiarid areas where nitrogen determines plant productivity...

Research Grants87

  1. Community-Based Participatory Approach to Farmworker Housing, Exposures & Health
    Thomas A Arcury; Fiscal Year: 2010
    ....
  2. Occupational Skin Disease Among Minority Farmworkers
    Thomas Arcury; Fiscal Year: 2007
    ..Finally, a clinic study will use telemedicine procedures to diagnosis OSD among 150 farm-workers who present at migrant clinics and delineate the risks associated with these diagnoses. ..
  3. Differences in CAM Use Among Minority Older Adults
    Thomas Arcury; Fiscal Year: 2005
    ..abstract_text> ..
  4. Farmwoker Environmental Health Research Comparable Data
    Thomas Arcury; Fiscal Year: 2004
    ..The purpose of limiting the size of the conference is to facilitate active interaction, discussion and debate among leaders in the field. ..
  5. LA FAMILIA REDUCING FARMWORKER PESTICIDE EXPOSURE
    Thomas Arcury; Fiscal Year: 2004
    ..while the results of the project are disseminated to regional and national farmworker groups, to those providing health care to farmworkers, and in the research literature. ..
  6. Casa A Campo: Pesticide Safety for Farmworkers' Families
    Thomas Arcury; Fiscal Year: 2004
    ....
  7. African American Men Prostate & Colorectal Cancer Belief
    Thomas Arcury; Fiscal Year: 2007
    ..A preliminary framework of the intervention strategy for this R01 application will be developed and evaluated as part of this project. ..
  8. Community Participatory Approach to Measuring Farmworker Pesticide Exposures: PAC
    Thomas Arcury; Fiscal Year: 2007
    ....
  9. Ethnic Variation in CAM Use and Health Self Management among Rural Older Adults
    Thomas Arcury; Fiscal Year: 2009
    ....
  10. Ethnic Variation in CAM Use and Health Self Management among Rural Older Adults
    Thomas Arcury; Fiscal Year: 2009
    ....
  11. Community-Based Participatory Approach to Farmworker Housing, Exposures & Health
    Thomas Arcury; Fiscal Year: 2009
    ....
  12. Community Participatory Approach to Measuring Farmworker Pesticide Exposures: PAC
    Thomas Arcury; Fiscal Year: 2009
    ....
  13. Ethnic Variation in CAM Use and Health Self Management among Rural Older Adults
    Thomas Arcury; Fiscal Year: 2007
    ....
  14. Fetal & Adolescent Nicotine Effects on CNS 5HT Systems
    Theodore Slotkin; Fiscal Year: 2003
    ..abstract_text> ..
  15. Cell-type specific targting of curcumin
    BIDDANDA PONNAPPA; Fiscal Year: 2005
    ..These studies will provide valuable pre-clinical information on the in vivo potential of the liposomal-curcumin formulation to abrogate liver metastasis of colorectal cancer. ..
  16. Targeting Kupffer Cells With Short-Interfering RNA
    BIDDANDA PONNAPPA; Fiscal Year: 2005
    ..A successful outcome of this study will greatly enhance our ability to use very low concentrations of gene-specific molecules for the treatment of disease such as alcoholic liver disease. ..
  17. New York State Angler Cohort Follow-up Study
    Matthew Bonner; Fiscal Year: 2009
    ..abstract_text> ..
  18. Developmental neurotoxicity of ethanol
    LUCIO COSTA; Fiscal Year: 2009
    ..Altogether, these studies are aimed at elucidating novel aspects of the communication between astrocytes and neurons and at characterizing new mechanisms involved in the developmental neurotoxicity of ethanol. ..
  19. Developmental neurotoxicity of ethanol
    Lucio G Costa; Fiscal Year: 2010
    ..Altogether, these studies are aimed at elucidating novel aspects of the communication between astrocytes and neurons and at characterizing new mechanisms involved in the developmental neurotoxicity of ethanol. ..
  20. DRUGS AND DEVELOPMENT OF ADRENERGIC NERVOUS SYSTEM
    Theodore Slotkin; Fiscal Year: 1980
    ....
  21. ETHANOL AND PHOSPHOINOSITIDES DURING BRAIN DEVELOPMENT
    LUCIO COSTA; Fiscal Year: 2000
    ..2. To investigate the molecular pathways involved in the observed inhibition by ethanol of the mitogenic action of acetylcholine in astrocytes. ..
  22. ETHANOL AND PHOSPHOINOSITIDES DURING BRAIN DEVELOPMENT
    LUCIO COSTA; Fiscal Year: 1993
    ....
  23. Developmental neurotoxicity of ethanol
    LUCIO COSTA; Fiscal Year: 2009
    ..Altogether, these studies are aimed at elucidating novel aspects of the communication between astrocytes and neurons and at characterizing new mechanisms involved in the developmental neurotoxicity of ethanol. ..
  24. DRUGS AND DEVELOPMENT OF THE ADRENERGIC NERVOUS SYSTEM
    Theodore Slotkin; Fiscal Year: 1992
    ....
  25. DRUGS AND DEVELOPMENT OF THE ADRENERGIC NERVOUS SYSTEM
    Theodore Slotkin; Fiscal Year: 2003
    ....
  26. MECHANISMS OF CHLORPYRIFOS DEVELOPMENTAL NEUROTOXICITY
    Theodore Slotkin; Fiscal Year: 2004
    ..Molecular mechanisms of developmental neurotoxicity can be determined and linked to eventual alterations in behavioral performance. ..