Genomes and Genes
Summary: Sodium or sodium compounds used in foods or as a food. The most frequently used compounds are sodium chloride or sodium glutamate.
Publications239 found, 100 shown here
- Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research GroupF M Sacks
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
N Engl J Med 344:3-10. 2001..We studied the effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is rich in vegetables, ..
- Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trialEduardo Pimenta
Hypertension Unit, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, QLD, Australia
Hypertension 54:475-81. 2009Observational studies indicate a significant relation between dietary sodium and level of blood pressure. However, the role of salt sensitivity in the development of resistant hypertension is unknown...
- Heritability of blood pressure responses to dietary sodium and potassium intake in a Chinese populationDongfeng Gu
Cardiovascular Institute and Fu Wai Hospital, Beijing, China
Hypertension 50:116-22. 2007..We examined the heritability of blood pressure responses to dietary sodium and potassium intake in a family feeding study among 1906 study participants living in rural North China...
- ACE inhibition has adverse renal effects during dietary sodium restriction in proteinuric and healthy ratsI Hamming
Department of Pathology and Laboratory Medicine, University Medical Center Groningen and University of Groningen, The Netherlands
J Pathol 209:129-39. 2006..Further studies should elucidate the mechanisms underlying these observations and their impact on long-term renoprotection...
- Sodium in the Finnish diet: II trends in dietary sodium intake and comparison between intake and 24-h excretion of sodiumH Reinivuo
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
Eur J Clin Nutr 60:1160-7. 2006To estimate cross-sectional and long-term dietary sodium intakes and sources in Finland, and to evaluate the validity of 48-h recall to assess sodium intake.
- Dietary sodium and the incidence of hypertension in the Chinese population: a review of nationwide surveysZhiquan Liu
Cardiovascular Division, Department of Internal Medicine, First Affiliated Hospital, Xi an Jiaotong University Medical School, Xi an, People s Republic of China
Am J Hypertens 22:929-33. 2009..High dietary salt consumption is considered a risk factor for hypertension...
- Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodiumGustavo Frindt
Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10065, USA
Am J Physiol Renal Physiol 297:F1249-55. 2009..We conclude that cleavage of gamma-ENaC and its expression at the apical surface play a major role in the regulation of renal Na reabsorption...
- Benefits of and barriers to dietary sodium adherenceJanet L Welch
Indiana University School of Nursing, Indianapolis, USA
West J Nurs Res 28:162-80; discussion 181-9. 2006Failure to limit dietary sodium leads to thirst, large fluid weight gain, and poor outcomes in patients receiving hemodialysis...
- Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trialsJ M Geleijnse
Division of Human Nutrition and Epidemiology, Wageningen University, The Netherlands
J Hum Hypertens 17:471-80. 2003..51 vs -0.34 mmHg, P=0.074). In conclusion, reduced intake of sodium and increased intake of potassium could make an important contribution to the prevention of hypertension, especially in populations with elevated blood pressure...
- Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trialFemke Waanders
Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Kidney Dis 53:16-25. 2009..We hypothesized that a decrease in proteinuria by using therapeutic interventions is associated with decreased urinary KIM-1 levels...
- Role of dietary sodium in osteoporosisRobert P Heaney
Creighton University, Omaha, Nebraska 68178, USA
J Am Coll Nutr 25:271S-276S. 2006..Given the relative difficulty of the former, and the ancillary benefits of the latter, it would seem that the optimal strategy to protect the skeleton is to ensure adequate calcium and potassium intakes...
- Dietary sodium intake and asthma: an epidemiological and clinical reviewT D Mickleborough
Department of Kinesiology, Human Performance and Exercise Biochemistry Laboratory, Indiana University, Bloomington, Indiana 47401, USA
Int J Clin Pract 60:1616-24. 2006..factors that may have contributed to the rise in the prevalence of asthma over the past few decades, and dietary sodium has been considered to be a dietary constituent which may be implicated in this phenomenon...
- Effect of dietary sodium chloride on gastro-oesophageal reflux: a randomized controlled trialMarissa C Aanen
Gastrointestinal Research Unit, University Medical Center, Utrecht, The Netherlands
Scand J Gastroenterol 41:1141-6. 2006..The objective of this study was to investigate the effect of increased dietary NaCl intake on gastro-oesophageal reflux and reflux mechanisms...
- The feasibility of implementing a dietary sodium reduction intervention among free-living normotensive individuals in south west NigeriaAdebowale A Adeyemo
College of Medicine, University of Ibadan, Nigeria
Ethn Dis 12:207-12. 2002..In this study, we tested the feasibility of achieving a reduction in dietary sodium intake in free-living individuals using a dietary intervention among 82 free-living normotensive adults in ..
- The influence of dietary sodium on blood pressureNorman K Hollenberg
Department of Medicine, Brigham and Women s Hospital and Harvard Medical Center, Boston, MA 02115, USA
J Am Coll Nutr 25:240S-246S. 2006..On the bright side, prognosis is improved substantially by the array of antihypertensive drugs available today...
- Dietary sodium effects on heart rate variability in salt sensitivity of blood pressureJessica D McNeely
Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
Psychophysiology 45:405-11. 2008High dietary sodium intake is a risk factor for hypertension, and heart rate variability (HRV) is decreased in hypertension. Effects of dietary sodium intake on HRV of normotensive persons have not, however, been investigated to date...
- Effects of dietary sodium and magnesium on cyclosporin A-induced hypertension and nephrotoxicity in spontaneously hypertensive ratsE M Mervaala
Institute of Biomedicine, Department of Pharmacology and Toxicology, University of Helsinki, Finland
Hypertension 29:822-7. 1997..In the present study, the effects of dietary sodium and magnesium on CsA toxicity were examined in spontaneously hypertensive rats...
- High dietary sodium intake increases white adipose tissue mass and plasma leptin in ratsMiriam H Fonseca-Alaniz
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, 1524 Prof Lineu Prestes Ave, 05508 900, Sao Paulo, SP, Brazil
Obesity (Silver Spring) 15:2200-8. 2007..Salt restriction has been reported to increase white adipose tissue (WAT) mass in rodents. The objective of this study was to investigate the effect of different sodium content diets on the lipogenic and lipolytic activities of WAT...
- Clustering of endothelial markers of vascular damage in human salt-sensitive hypertension: influence of dietary sodium load and depletionC Ferri
University La Sapienza, Chair of I Clinica Medica, Andrea Cesalpino Foundation, Departments of Experimental Medicine, A s, University of L Aquila, L Aquila, Italy
Hypertension 32:862-8. 1998..Our findings support the hypothesis that salt sensitivity is correlated with an increased risk for developing hypertension-related cardiovascular damage...
- How far should salt intake be reduced?Feng J He
Blood Pressure Unit, St George s Hospital Medical School, Cranmer Terrace, London, England
Hypertension 42:1093-9. 2003..A further reduction to 3 g/d will have a much greater effect and should now become the long-term target for population salt intake worldwide...
- Modulation by dietary sodium intake of melanocortin 3 receptor mRNA and protein abundance in the rat kidneyXi Ping Ni
Division of Nephrology, San Francisco General Hospital, California, USA
Am J Physiol Regul Integr Comp Physiol 290:R560-7. 2006..001). No significant increase occurred in the cortex. The increase in MC3-R expression induced by dietary sodium was observed in inner medullary collecting duct (IMCD) cells isolated from the kidneys of HSD rats, suggesting ..
- Influence of an enriched dietary sodium chloride regime during gestation and suckling and post-natally on the ontogeny of hypertension in the ratN Hazon
Department of Zoology, University of Sheffield, UK
J Hypertens 6:517-24. 1988..abstract truncated at 250 words)..
- Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodiumG F DiBona
Department of Internal Medicine, University of Iowa College of Medicine and Veterans Administration Medical Center, Iowa City, IA 52242, USA
Acta Physiol Scand 177:285-9. 2003..an intact blood-brain barrier to assess the role of endogenous angII of brain origin and (c) alterations in dietary sodium intake, a known physiological regulator of activity of the renin-angiotensin system (RAS), to assess the ..
- Effects of aging and alterations in dietary sodium intake on total nitric oxide productionR J Schmidt
Departments of Medicine and Physiology, West Virginia University, Morgantown, WV 26506, USA
Am J Kidney Dis 37:900-8. 2001..Limitations of blood and urine measurements of NO(2) + NO(3) and cGMP as indices of NO activity are discussed...
- A review of methods to measure dietary sodium intakeBrooke Bentley
Student College of Nursing, University of Kentucky, Lexington, KY, USA
J Cardiovasc Nurs 21:63-7. 2006With the rising prevalence of heart failure, it is imperative to investigate reasons for dietary sodium nonadherence and to develop evidence-based interventions to promote adherence...
- Dietary sodium deprivation evokes activation of brain regional neurons and down-regulation of angiotensin II type 1 receptor and angiotensin-convertion enzyme mRNA expressionB Lu
Department of Physiology and Pathophysiology, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, School of Medicine, Xi an Jiaotong University, 76 W Yanta Road, Xi an, 710061, PR China
Neuroscience 164:1303-11. 2009..system (RAAS) is implicated in the induction of sodium appetite in rats and that different dietary sodium intakes influence the mRNA expression of central and peripheral RAAS components...
- Changes in urinary stone risk factors in hypocitraturic calcium oxalate stone formers treated with dietary sodium supplementationMarshall L Stoller
Department of Urology, School of Medicine, University of California San Francisco, San Francisco, California, USA
J Urol 181:1140-4. 2009We investigated the effects of supplemental dietary sodium on risk factors for urinary stone disease in stone forming patients with hypocitraturia.
- Dietary sodium: the dark horse amongst cardiovascular and renal risk factorsAlbert Mimran
Department of Internal Medicine, Hopital Lapeyronie, Montpellier Cedex, France
Nephrol Dial Transplant 23:2138-41. 2008
- Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in CanadaMichel R Joffres
Simon Fraser University, Burnaby, British Columbia, Canada
Can J Cardiol 23:437-43. 2007..Reductions in dietary sodium additives significantly lower systolic and diastolic blood pressure, and population reductions in dietary ..
- Urinary sodium excretion and cardiovascular mortality in Finland: a prospective studyJ Tuomilehto
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
Lancet 357:848-51. 2001..We aimed to find out whether salt intake, measured by 24 h urinary sodium excretion, is an independent risk factor for cardiovascular disease frequency and mortality, and all-cause mortality...
- Dietary sodium intake and subsequent risk of cardiovascular disease in overweight adultsJ He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
JAMA 282:2027-34. 1999b>Dietary sodium is positively associated with blood pressure, and ecological and animal studies both have suggested that high dietary sodium intake increases stroke mortality.
- Long-term effects of weight loss and dietary sodium reduction on incidence of hypertensionJ He
Department of Epidemiology, the Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112 2699, USA
Hypertension 35:544-9. 2000To examine the long-term effects of weight loss and dietary sodium reduction on the incidence of hypertension, we studied 181 men and women who participated in the Trials of Hypertension Prevention, phase 1, in Baltimore, Md...
- Increased dietary sodium alters Fos expression in the lamina terminalis during intravenous angiotensin II infusionSteven L Bealer
Department of Pharmacology and Toxicology, College of Pharmacy, 20 South 3000 East, Rm 201, University of Utah, Salt Lake City, UT 84121, USA
Exp Neurol 204:299-306. 2007These studies examined the effects of increased dietary sodium on expression of Fos, the protein product of c-fos, in forebrain structures in the rat following intravenous infusion with angiotensin II (AngII)...
- High-salt diet induces gastric epithelial hyperplasia and parietal cell loss, and enhances Helicobacter pylori colonization in C57BL/6 miceJ G Fox
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge 02139, USA
Cancer Res 59:4823-8. 1999..pylori colonization. Furthermore, elevated salt intake may potentiate H. pylori-associated carcinogenesis by inducing proliferation, pit cell hyperplasia, and glandular atrophy...
- Effect of renin-angiotensin system activation by dietary sodium restriction and upright position on plasma leptin concentration in patients with essential hypertensionMarcin Adamczak
Department of Nephrology, Endocrinology and Metabolic Diseases, Silesian Medical University, Katowice, Poland
Med Sci Monit 8:CR473-7. 2002..This study was undertaken to assess the relationship between RAS and plasma leptin concentration in hypertensive patients under conditions of normal and restricted sodium supply and upright position...
- A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: results of the DASH-Sodium TrialGeorge A Bray
Pennington Biomedical Research Center, Baton Rouge, Lousiana, USA
Am J Cardiol 94:222-7. 2004....
- Effect of aerobic exercise training on blood pressure sensitivity to dietary sodium in older hypertensivesD R Dengel
School of Kinesiology, University of Minnesota, Minneapolis, 55455, USA
J Hum Hypertens 20:372-8. 2006..exercise training has been shown to lower blood pressure (BP) in older adults, its effect on BP sensitivity to dietary sodium (Na(+)) is unknown...
- Dietary sodium as a risk factor for osteoporosis: where is the evidence?Birgit Teucher
Nutrition Division, Institute of Food Research, Norwich NR4 7UA, UK
Proc Nutr Soc 62:859-66. 2003..g. salt sensitivity). The reasons for inter-individual variability should be explored using post-genomic techniques...
- Sodium intake and risk of death from stroke in Japanese men and womenChisato Nagata
Department of Epidemiology and Preventive Medicine, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
Stroke 35:1543-7. 2004..The purpose of this study was to examine the relation between sodium intake and death from stroke in a population-based cohort of Japanese men and women...
- Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trialDavid W Harsha
Pennington Biomedical Research Center, Baton Rouge, LA, USA
Hypertension 43:393-8. 2004..There were no significant interactions between the effects of sodium and the DASH diet on serum lipids. In conclusion, changes in dietary sodium intake over the range of 50 to 150 mmol/d did not affect blood lipid concentrations.
- Relations between dietary sodium and potassium intakes and mortality from cardiovascular disease: the Japan Collaborative Cohort Study for Evaluation of Cancer RisksMitsumasa Umesawa
Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, and the Institute of Community Medicine, University of Tsukuba, Tsukuba, Japan
Am J Clin Nutr 88:195-202. 2008..Limited evidence is available about the relations between sodium and potassium intakes and cardiovascular disease in the general population...
- Sodium intake and mortality follow-up in the Third National Health and Nutrition Examination Survey (NHANES III)Hillel W Cohen
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Gen Intern Med 23:1297-302. 2008..Sodium restriction is commonly recommended as a measure to lower blood pressure and thus reduce cardiovascular disease (CVD) and all-cause mortality. However, some studies have observed higher mortality associated with lower sodium intake...
- Reducing dietary sodium and decreases in cardiovascular disease in CanadaErika D Penz
Department of Medicine, University of Calgary, Calgary, Alberta
Can J Cardiol 24:497-1. 2008Increases in dietary sodium increase blood pressure, whereas emerging evidence confirms that the reduction in dietary sodium results in reduced cardiovascular events.
- Influence of dietary sodium on the blood pressure and renal sympathetic nerve activity responses to intracerebroventricular angiotensin II and angiotensin III in anaesthetized ratsBelinda L Houghton
Department of Physiology, Windle Building, University College Cork, College Road, Cork, Republic of Ireland
Exp Physiol 95:282-95. 2010..c.v. AngII and AngIII; (2) highlight an important role for peripheral V(1) receptors during these responses; and (3) differentiate the effects of AngII and AngIII on blood pressure and RSNA...
- Efficacy of nonpharmacologic interventions in adults with high-normal blood pressure: results from phase 1 of the Trials of Hypertension Prevention. Trials of Hypertension Prevention Collaborative Research GroupP K Whelton
Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University School of Hygiene and Public Health, Baltimore, USA
Am J Clin Nutr 65:652S-660S. 1997..These results suggest that both weight loss and sodium reduction provide an effective means to prevent hypertension. The long-term effects of both of these interventions are being tested in phase 2 of the trial...
- Renal denervation chronically lowers arterial pressure independent of dietary sodium intake in normal ratsFrederic Jacob
Department of Physiology, Lillehei Heart Institute, University of Minnesota, Minneapolis 55455, USA
Am J Physiol Heart Circ Physiol 284:H2302-10. 2003..Overall, there were no between-group differences in sodium or water balance in either protocol. We conclude that renal nerves support basal levels of AP, irrespective of dietary sodium intake in normal rats.
- Randomized trials of sodium reduction: an overviewJ A Cutler
Division of Epidemiology and Clinical Applications, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Am J Clin Nutr 65:643S-651S. 1997..The blood pressure reduction that would result from a substantial lowering of dietary sodium in the US population could reduce cardiovascular morbidity and mortality.
- Reducing the public health burden from elevated blood pressure levels in the United States by lowering intake of dietary sodiumStephen Havas
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, 21201, USA
Am J Public Health 94:19-22. 2004..Such a reduction would greatly enhance the chances of attaining the Healthy People 2010 objectives and would save at least 150 000 lives annually. This issue warrants public health intervention...
- Changes in dietary sodium consumption modulate GLUT4 gene expression and early steps of insulin signalingMaristela Mitiko Okamoto
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, 1524 05508 900, Sao Paulo, Brazil
Am J Physiol Regul Integr Comp Physiol 286:R779-85. 2004..In the present study we investigated the influence of dietary sodium on 1) GLUT4 gene expression, by No the n and Western blotting analysis; 2) in vivo GLUT4 protein translocation,..
- Evidence relating dietary sodium to cardiovascular diseaseMichael H Alderman
Albert Einstein College of Medicine, Dept of Epidemiology and Population Health, Bronx, New York 10461, USA
J Am Coll Nutr 25:256S-261S. 2006The expectation that dietary sodium intake might influence cardiovascular disease occurrence has been based upon its impact on blood pressure (BP)...
- Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting systemDominique Loffing-Cueni
University of Fribourg, Department of Medicine Anatomy, Route Albert Gockel 1, CH 1700 Fribourg, Switzerland
J Am Soc Nephrol 17:1264-74. 2006..It is concluded that Nedd4-2 abundance is regulated by Na(+) diet, by a mechanism that likely involves aldosterone. This regulation may contribute to adaptation of apical ENaC activity to altered Na(+) intake...
- Evidence-based politics of salt and blood pressureQais Al-Awqati
Kidney Int 69:1707-8. 2006
- Dietary sodium and target organ damage in essential hypertensionGuilhem du Cailar
Department of Internal Medicine and Hypertension, Hopital Lapeyronie, Montpellier, France
Am J Hypertens 15:222-9. 2002In addition to its widely contested influence on arterial pressure, dietary sodium may exert some nonpressure-related effects on left ventricular mass in humans...
- Sodium intake affects urinary albumin excretion especially in overweight subjectsJ C Verhave
Division of Nephrology, Department of Medicine, University Medical Center Groningen, Groningen University Institute of Drug Exploration GUIDE, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
J Intern Med 256:324-30. 2004..To examine the relationship between sodium intake and urinary albumin excretion, being an established risk marker for later cardiovascular morbidity and mortality...
- Presidential Address: 21st Scientific Meeting of the International Society of Hypertension: dietary sodium and cardiovascular disease: the 'J'-shaped relationMichael H Alderman
Albert Einstein College of Medicine, Department of Epidemiology and Population Health, 1300 Morris Park Avenue, Bronx, New York 10461, USA
J Hypertens 25:903-7. 2007
- Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertensionPhillip E Gates
Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
Hypertension 44:35-41. 2004We determined the temporal effects of dietary sodium restriction on large elastic artery compliance and systolic blood pressure (SBP) in 12 untreated, older (64+/-2 years) men and women (6 each) with stage 1 systolic hypertension...
- Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive ratsWataru Aoi
Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602 8566, Japan
Cell Biol Int 31:1288-91. 2007..the kidney of Dahl salt-sensitive (DS) rats was abnormally regulated by aldosterone, however it is unknown if dietary sodium affects the expression of ENaC and serum and glucocorticoid-regulated kinase 1 (SGK1), which plays an ..
- Dietary sodium intake and mortality: the National Health and Nutrition Examination Survey (NHANES I)M H Alderman
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Lancet 351:781-5. 1998Population-wide restriction of dietary sodium has been recommended. However, little evidence directly links sodium intake to morbidity and mortality...
- Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animalsNatalya Bodyak
Cardiovascular Division and Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 104:16810-5. 2007..In summary, PC attenuates the development of LV alterations in DSS rats, and these effects should be examined in human clinical trials...
- Reducing dietary sodium intake: the Canadian contextSusan I Barr
Food, Nutrition, and Health, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Appl Physiol Nutr Metab 35:1-8. 2010..men and two thirds of Canadian women have sodium intakes above the UL, Health Canada's Working Group on Dietary Sodium Reduction has been charged with developing, implementing, and overseeing a strategy to reduce Canadians' ..
- The dietary sodium-blood pressure plot "stiffens"Alexei Y Bagrov
Hypertension 44:22-4. 2004
- Extrarenal ETB plays a significant role in controlling cardiovascular responses to high dietary sodium in ratsMamoru Ohkita
Department of Pediatrics, University of Michigan, Ann Arbor 48109 0656, USA
Hypertension 45:940-6. 2005..caused by an absence of renal ET(B) signaling and performed a series of experiments to examine the effect of dietary sodium (Na) on endothelin-1 (ET1) expression and renal function in wild-type (WT) and ET(B)-deficient rats...
- Reducing the population burden of cardiovascular disease by reducing sodium intake: a report of the Council on Science and Public HealthBarry D Dickinson
American Medical Association, 515 N State St, Chicago, IL 60610, USA
Arch Intern Med 167:1460-8. 2007..In the continued absence of voluntary measures adopted by the food industry, new regulations will be required to achieve lower sodium concentrations in processed and prepared foods...
- Effects of dietary sodium and genetic background on angiotensinogen and Renin in mousePierre Lantelme
Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City, USA
Hypertension 39:1007-14. 2002..The response of this tubular renin-angiotensin system to stepwise changes in dietary sodium was investigated in 2 mouse strains, the sodium-sensitive inbred C57BL/6 and the sodium-resistant CD1 outbred...
- Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clusteringB M Egan
Department of Pharmacology, Medical University of South Carolina, Charleston 29425
Am J Hypertens 7:886-93. 1994..Plasma renin activity also tended to increase more on the low salt diet in the high risk group. Ambulatory blood pressures were greater on the low than the high salt diet only in the high risk group.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Negative regulators of sodium transport in the kidney: key factors in understanding salt-sensitive hypertension?Bernard C Rossier
Institut de Pharmacologie et de Toxicologie, Universite de Lausanne, Lausanne, Switzerland
J Clin Invest 111:947-50. 2003
- The contribution of brain angiotensin II to the baroreflex regulation of renal sympathetic nerve activity in conscious normotensive and hypertensive ratsChunlong Huang
Department of Physiology, Aras Windle, University College Cork, Cork, Republic of Ireland
J Physiol 574:597-604. 2006..indicate that in the conscious state, the tonic inhibitory action of brain angiotensin II on the baroreflex regulation of renal sympathetic nerve activity was unaffected by raised dietary sodium, but its role was enhanced in the SHRSPs.
- Nonmodulating trait may precede the development of hypertensionM S Gordon
Endocrine-Hypertension Division, Brigham and Women's Hospital, Boston, Massachusetts 02115-5817
Am J Hypertens 7:789-93. 1994..We conclude that the nonmodulating trait may be a heritable defect that leads to the development of hypertension and is not an epiphenomenon...
- [Renin-angiotensin-aldosterone system and natriuretic peptide system--reference to cardiovascular diseases]Hirofumi Yasue
Kumamoto Aging Research Institute
Nihon Rinsho 62:164-9. 2004
- Pulse-pressure-driven neutral lipid accumulation and correlative proinflammatory markers of accelerated atherogenesisCharles R Kiefer
Department of Hospital Laboratories, UMass Memorial Medical Center, One Biotech Park, Suite 200, 365 Plantation Street, Worcester, MA 01605 2376, USA
Atherosclerosis 183:17-24. 2005..weaning on a high-saturated fat, high-cholesterol diet until early adolescence (age 12 weeks), at which point dietary sodium was increased, and changes in blood pressure, serum analytes and histologic markers were tracked...
- Low-dose lithium combined with captopril prevents stroke and improves survival in salt-loaded, stroke-prone spontaneously hypertensive ratsJihong Xu
Institute of Pharmacology, University Hospital of Schleswig Holstein, Campus Kiel, Germany
J Hypertens 23:2277-85. 2005..In the present study, we investigated the effects of a low-dose combination treatment with lithium and captopril on survival and stroke prevention in salt-loaded, stroke-prone spontaneously hypertensive rats (SHRSP)...
- The occurrence of parathyroid hypertensive factor (PHF) in Dahl ratsR Z Lewanczuk
Department of Physiology, University of Alberta, Edmonton, Canada
Am J Hypertens 6:758-62. 1993..50, P = .0077). These results show that Dahl-S rats are capable of expressing PHF-like activity, which is induced by increasing dietary salt intakes.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Chronic blockade of neuronal nitric oxide synthase does not affect long-term control of blood pressure in normal, saline-drinking or deoxycorticosterone-treated ratsRosemary Wangensteen
Departamento de Fisiologia, Facultad de Medicina, Servicio de Nefrologia, Unidad Experimental, Hospital Virgen de las Nieves, Granada, Spain
Exp Physiol 88:243-50. 2003..Furthermore, the nNOS blockade does not interfere with the counterbalance between renin and an increased sodium intake or retention...
- Renal interstitial Ca2+ during sodium loading of normotensive and Dahl-salt hypertensive ratsCassandra E Palmer
Cardiovascular Disease Research Program, Biomedical Biotechnology Research Institute, North Carolina Central University, 700 George Street, Durham, NC 27707, USA
Am J Hypertens 16:771-6. 2003....
- [Abnormalities of renal sodium transport and blood pressure sensitivity to salt]M Burnier
Service de Néphrologie et Hypertension, Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 17, 1011 Lausanne, Switzerland
Nephrol Ther 3:S94-8. 2007..There is now also extending experimental, clinical, genetic and epidemiological evidence suggesting that proximal tubular function is an important determinant of the blood pressure response to salt that would deserve a greater attention...
- [Salt restriction in treatment of diabetes mellitus]Masahiro Motokawa
Department of Internal Medicine and Pathophysiology, Nagoya City University Graduate School of Medical Sciences
Nihon Rinsho 63:417-23. 2005
- Dietary sodium and blood pressureDaniel W Jones
Office of the Vice Chancellor, University of Mississippi Medical Center, 2500 North State Street Jackson, MS 39216 4505, USA
Hypertension 43:932-5. 2004
- G-protein beta-3 subunit gene C825 T polymorphism: influence on plasma sodium and potassium concentrations in essential hypertensive patientsDolores Nieto Martín
Unidad de Hipertensión Arterial y Lípidos, Servicio de Medicina Interna, Hospitales Universitarios Virgen del Rocio, Avenida Manuel Siurot s n, 41013 Sevilla, Spain
Life Sci 77:2879-86. 2005....
- Marinobufagenin, an endogenous alpha-1 sodium pump ligand, in hypertensive Dahl salt-sensitive ratsO V Fedorova
Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, Baltimore, MD, USA
Hypertension 37:462-6. 2001..MBG acts as a selective inhibitor of the ouabain-resistant alpha-1 Na(+)/K(+)-ATPase subunit, ie, the major sodium pump isoform of the kidneys, as would be expected of a putative natriuretic hormone...
- [Promoter variants of aldosterone synthase gene (CYP11B2) and salt-sensitivity of blood pressure]Agnieszka Wrona
Samodzielna Pracownia Patobiochemii i Biologii Molekularnej Pomorskiej AM w Szczecinie
Pol Arch Med Wewn 111:191-7. 2004..Our preliminary results suggest the lack of association of the T(-344)C CYP11B2 polymorphism with salt-sensitive hypertension as well as with activity of plasma renin-angiotensin-aldosterone system in Caucasian patients...
- Salt sensitivity of children with low birth weightGiacomo D Simonetti
Department of Nephrology, Inselspital, Bern University Hospital, University of Bern, Berne, Switzerland
Hypertension 52:625-30. 2008..Whether the changes in renal growth are causative or are the consequence of the same abnormal "fetal programming" awaits clarification...
- Circulating coupling factor 6 in human hypertension: role of reactive oxygen speciesTomohiro Osanai
Second Deparment of Internal Medicine, Hirosaki University School of Medicine, Japan
J Hypertens 21:2323-8. 2003..Coupling factor 6 is an endogenous inhibitor of prostacyclin synthesis and might function as an endogenous vasoconstrictor in the fashion of a circulating hormone in rats. We investigated the role of coupling factor 6 in human hypertension...
- Diet and blood pressure in South Africa: Intake of foods containing sodium, potassium, calcium, and magnesium in three ethnic groupsKaren E Charlton
Chronic Diseases of Lifestyle Unit, Medical Research Council, Tygerberg, South Africa
Nutrition 21:39-50. 2005....
- DuP 753 increases survival in spontaneously hypertensive stroke-prone rats fed a high sodium dietM J Camargo
Department of Medicine, Cornell University Medical Center, New York, NY 10021
Am J Hypertens 4:341S-345S. 1991..Survival at 12 weeks was 84% in DuP 753-treated group and 26% in the untreated group. The data demonstrate that DuP 753 decreased mortality and dramatically blunted the blood pressure rise in SHRsp fed a high sodium diet...
- Long-term effect of nifedipine and hydrochlorothiazide on blood pressure and sodium homeostasis at varying levels of salt intake in mildly hypertensive patientsF C Luft
Department of Internal Medicine-Nephrology, , Germany
Am J Hypertens 4:752-60. 1991..The PRA appears inactivated, although not lowered. The effects of NIF on BP may be at least in part related to the natriuresis and blunting of PRA.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Plasma sodium-potassium ATPase inhibition activity in low- and normal-renin hypertensionP Keane
Foothills Provincial General Hospital, Faculty of Medicine, University of Calgary, Alberta, Canada
Am J Hypertens 4:9-13. 1991..384, P = .019). Plasma NKAIA is related to mean arterial pressure or urinary sodium excretion depending on the dietary sodium intake, and is related to sodium-induced changes in MAP in low and normal renin hypertensive patients.
- Plasma sodium: ignored and underestimatedFeng J He
Blood Pressure Unit, St George s Hospital Medical School, London, UK
Hypertension 45:98-102. 2005..Small changes in plasma sodium alter extracellular volume, which may influence blood pressure. Changes in plasma sodium may also affect blood pressure directly...
- Salt and hypertension: a phylogenetic perspectiveArye Lev-Ran
Maccabi Health Services, Petah Tikva, Israel
Diabetes Metab Res Rev 21:118-31. 2005....
- Role of cyclooxygenase-2 in the prolonged regulation of renal functionFrancisco Roig
Departamento de Fisiologia, Facultad de Medicina, Murcia, Spain
Hypertension 40:721-8. 2002....
- Coordinate regulation of canine glomeruli and adrenal angiotensin receptors by dietary sodium manipulationW Zheng
Division of Nephrology and Hypertension, Department of Medicine, Georgetown University, Washington DC 20007-2145, USA
Kidney Int 59:1881-90. 2001BACKGROUND: This study evaluated the effects of dietary sodium manipulation in dogs on the regulation of canine angiotensin receptors (cAT1 and cAT2) in the kidney and adrenal...
- Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S ratsBinhui Liang
From the Hypertension Unit, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Cardiovasc Pharmacol 51:457-66. 2008..In Dahl S rats, AT1-receptor stimulation seems to play a critical role in salt-induced hypertension and fibrosis, but a lesser role in tissue hypertrophy...
- The impact of daily sodium intake on posttransplant hypertension in kidney allograft recipientsK Keven
Ankara University School of Medicine, Department of Nephrology, Ankara, Turkey
Transplant Proc 38:1323-6. 2006..Although dietary sodium restriction is a widely recommended nonpharmacological measure for control of blood pressure (BP), no detailed ..
- Renal endothelin ET(A)/ET(B) receptor imbalance differentiates salt-sensitive from salt-resistant spontaneous hypertensionL Rothermund
, Benjamin Franklin Hospital, , Berlin, Germany
Hypertension 37:275-80. 2001..05). Thus, activation of the renal ET system together with an increased ET(A)/ET(B) receptor ratio may contribute to the development and progression of SS-SH...
- Salt sensitivity: a consequence of the metabolic syndrome?Olle Melander
J Hypertens 24:1475-7. 2006
- Enhanced sodium sensitivity and disturbed circadian rhythm of blood pressure in essential hypertensionTakashi Uzu
Department of Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan
J Hypertens 24:1627-32. 2006....
- The in vivo effects of Tulbhagia violacea on blood pressure in a salt-sensitive rat modelIrene Mackraj
Pfizer Molecular Biology Research Facility, University of KwaZulu Natal, Durban 4000, South Africa
J Ethnopharmacol 117:263-9. 2008..The in vivo effects of Tulbhagia violacea on systemic arterial blood pressure and on the renin-angiotensin system in a Dahl salt-sensitive rat model were investigated...
- Effects of changes in sodium balance on plasma and kidney angiotensin II levels in anesthetized and conscious Ren-2 transgenic ratsZuzana Husková
Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
J Hypertens 24:517-27. 2006....
- Salt-sensitive hypertension in ANP knockout mice: potential role of abnormal plasma renin activityL G Melo
Department of Physiology, University of Toronto, Ontario, Canada
Am J Physiol 274:R255-61. 1998....
- Congenic strains reveal the effect of the renin gene on skeletal muscle angiogenesis induced by electrical stimulationMicheline M de Resende
Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Physiol Genomics 33:33-40. 2008..The present study emphasizes the importance of maintaining normal renin regulation as well as ANG II levels during the angiogenesis process with a combination of physiological, genetic, and pharmacological manipulation of the RAS...
- Neuronal responsiveness to central Na+ in 2 congenic strains of Dahl salt-sensitive ratsBing S Huang
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Hypertension 49:1315-20. 2007..However, neither of them contributes to the increase in cerebrospinal fluid [Na(+)] induced by high salt...
- Uninephrectomy in young age or chronic salt loading causes salt-sensitive hypertension in adult ratsMattias Carlström
Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
Hypertension 49:1342-50. 2007..In conclusion, at a young age after completed nephrogenesis, uninephrectomy or chronic salt loading causes renal and cardiovascular injury with salt-sensitive hypertension...
- Sodium and Cardiovascular Disease in Patients with Chronic Kidney DiseaseJiang He; Fiscal Year: 2009..The few prospective epidemiologic studies that examined the relationship between dietary sodium and potassium intake and risk of CVD provided contradictory findings...
- Sodium and Cardiovascular Disease in Patients with Chronic Kidney DiseaseJiang He; Fiscal Year: 2010..The few prospective epidemiologic studies that examined the relationship between dietary sodium and potassium intake and risk of CVD provided contradictory findings...
- HYPERTENSION IN POPULATIONS OF WEST AFRICAN ORIGINRichard Cooper; Fiscal Year: 2007..propose to examine in further detail the role of the two most potent hypertensive risk factors, namely dietary sodium and obesity...
- NITRIC OXIDE AND HEREDITARY LOW-RENIN HYPERTENSIONPaul Sanders; Fiscal Year: 1993..of salt-sensitive hypertension; 2) demonstrate modulation of NO production in response to changes in dietary sodium chloride intake and/or L-arginine and determine the role of NO and L-arginine on renal handling of sodium ..
- REVERSAL OF MYOCARDIAL HYPERTROPHY IN HYPERTENSIONSubha Sen; Fiscal Year: 1993..Influential factors are dietary sodium, catecholamines, and many pharmacological agents used as antihypertensive drugs...
- REVERSAL OF MYOCARDIAL HYPERTROPHY IN HYPERTENSIONSubha Sen; Fiscal Year: 2002..Influential factors are dietary sodium, catecholamines, and many pharmacological agents used as antihypertensive drugs...
- Beta2-Adrenergic Receptor Gene Variation and Cardiovascular Control in HumansJohn Eisenach; Fiscal Year: 2009..to sympathoexcitatory maneuvers like mental stress and handgrip, 2-mediated cardiac and vascular function, and dietary sodium manipulation...
- Beta2-Adrenergic Receptor Gene Variation and Cardiovascular Control in HumansJohn Eisenach; Fiscal Year: 2009..to sympathoexcitatory maneuvers like mental stress and handgrip, 2-mediated cardiac and vascular function, and dietary sodium manipulation...
- Beta2-Adrenergic Receptor Gene Variation and Cardiovascular Control in HumansJohn H Eisenach; Fiscal Year: 2010..to sympathoexcitatory maneuvers like mental stress and handgrip, 2-mediated cardiac and vascular function, and dietary sodium manipulation...
- INTRARENAL REGULATION OF SODIUM EXCRETIONJohn Burnett; Fiscal Year: 2004..Recognizing the increase of dietary sodium intake in the US, the hypothesis that dietary sodium excess contributes to progressive ventricular remodeling ..
- Degenerative Changes in the Taste SystemLYNNETTE MCCLUSKEY; Fiscal Year: 2007..Indeed, there is evidence that dietary sodium restriction is immunosuppressive...
- gamma-MSH and Sodium MetabolismMichael Humphreys; Fiscal Year: 2007Variations in dietary sodium intake initiate integrated adjustments in neural and hormonal systems regulating sodium excretion by the kidneys in order to maintain overall sodium balance...
- SODIUM INTAKE AND CALCIUM RETENTION IN ADOLESCENT GIRLSConnie Weaver; Fiscal Year: 2001..The primary aim of this proposal is to test the hypothesis that high dietary sodium increases the calcium intakes required for optimal calcium retention in both black and white adolescent girls...
- INTRARENAL REGULATION OF SODIUM EXCRETIONJohn Burnett; Fiscal Year: 2000..While dietary sodium restriction is employed as the first step in the treatment of CHF to limit sodium accumulation, we hypothesize ..
- REGULATION OF THICK ASCENDING LIMB ACID-BASE TRANSPORTDavid Good; Fiscal Year: 1993..the effects on individual membrane transporters of factors such as vasopressin, dietary sodium intake, and chronic metabolic acidosis that regulate transcellular bicarbonate absorption, III...
- Family-Based Genome-wide Association Study for Salt-Sensitivity of Blood PressureJiang He; Fiscal Year: 2010..to localize and identify genetic variants which determine an individual's blood pressure (BP) response to dietary sodium intake by conducting a two-stage genome-wide association (GWA) study using the data and DNA specimens ..
- A Family Partnership Intervention for Heart FailureSandra Dunbar; Fiscal Year: 2009..Patient variables and measures are dietary sodium (24-hour urinary sodium), medication adherence to HF drugs including angiotensin converting enzyme inhibitors ..
- NEURAL CONTROL OF FLUID HOMEOSTASIS IN HYPERTENSIONGregory Fink; Fiscal Year: 2001..This is particularly the case where dietary sodium chloride (salt) intake is high...
- VASOPRESSIN RECEPTOR AND HYPERTENSIONMarc Thibonnier; Fiscal Year: 1992..and DOCA-salt hypertensive models) of the regulation of both types of AVP receptors during alterations of dietary sodium intake, of circulating AVP concentration and of blood pressure...