Genomes and Genes
Summary: Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)
Publications266 found, 100 shown here
- Three novel, structurally unique spirocyclic alkaloids from the halotolerant B-17 fungal strain of Aspergillus variecolorWen Liang Wang
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China
Chem Biodivers 4:2913-9. 2007..All compounds were shown to exhibit weak cytotoxic and antioxidant activities...
- When do water-insoluble polyion-surfactant ion complex salts "redissolve" by added excess surfactant?Salomé dos Santos
Division of Physical Chemistry, Department of Chemistry, Lund University, P O Box 124, SE 22100 Lund, Sweden
Langmuir 27:592-603. 2011..A number of stoichiometric polyion-surfactant ion "complex salts" were synthesized and they consisted of akyltrimethylammonium surfactant ions of two different alkyl chain ..
- Contribution of surface salt bridges to protein stabilityP Strop
Biochemistry Option, California Institute of Technology, Pasadena, California 91125, USA
Biochemistry 39:1251-5. 2000..5 kcal mol(-)(1). The entropic cost of making a surface salt bridge involving the protein's backbone is reduced, since the backbone has already been immobilized upon protein folding...
- Bartter syndromes and other salt-losing tubulopathiesRobert Kleta
Section on Human Biochemical Genetics, Medical Genetics Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA
Nephron Physiol 104:p73-80. 2006..We summarize recent findings in the field in the context of human diseases and a pathophysiologic basis for their treatment...
- Important roles of drought- and cold-inducible genes for galactinol synthase in stress tolerance in Arabidopsis thalianaTeruaki Taji
Laboratory of Plant Molecular Biology, RIKEN Tsukuba Institute, 3 1 1 Koyadai, Tsukuba, Ibaraki 305 0074, Japan
Plant J 29:417-26. 2002....
- Contribution of surface salt bridges to protein stability: guidelines for protein engineeringGeorge I Makhatadze
Department of Biochemistry and Molecular Biology, College of Medicine, Penn State University, 500 UniversityDrive, Hershey, PA 17033 2390, USA
J Mol Biol 327:1135-48. 2003..Implications of these findings for engineering proteins with enhanced thermostability are discussed...
- Salt bridges in the hyperthermophilic protein Ssh10b are resilient to temperature increasesMeng Ge
Key Laboratory of Bioinformatics, Ministry of Education, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China
J Biol Chem 283:31690-6. 2008..Implications of this finding are useful for engineering proteins with enhanced thermostability...
- The polyamine spermine protects against high salt stress in Arabidopsis thalianaKoji Yamaguchi
Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi 980-8577, Japan
FEBS Lett 580:6783-8. 2006..The data suggest that the absence of spermine causes an imbalance in Ca(2+) homeostasis in the mutant plant. Based on the data obtained, we propose a model for a role of spermine in high salt stress responses...
- Conformation and stability of alpha-helical membrane proteins. 2. Influence of pH and salts on stability and unfolding of rhodopsinReiner Vogel
Biophysics Group, Institut für Molekulare Medizin und Zellforschung, Albert Ludwigs Universitat Freiburg, Hermann Herder Strasse 9, D 79104 Freiburg, Germany
Biochemistry 41:3536-45. 2002..We further characterized the influence of salts on the stability of the rhodopsin helix bundle, which was found to follow the Hofmeister series...
- Toward the physical basis of thermophilic proteins: linking of enriched polar interactions and reduced heat capacity of unfoldingHuan Xiang Zhou
Institute of Molecular Biophysics and Department of Physics, Florida State University, Tallahassee, FL 32306, USA
Biophys J 83:3126-33. 2002..A reduced DeltaC(p) might serve as an indicator for the contribution of polar interactions to folding stability...
- Effect of salts on the structural behavior of hPrP alpha2-helix-derived analogues: the counterion perspectiveLuisa Ronga
Dipartimento delle Scienze Biologiche, C.I.R.Pe.B, , CNR, Via Mezzocannone 16, 80134 Napoli, Italy
J Pept Sci 12:790-5. 2006..Employment of various sodium salts allowed us to highlight the fact that chaotropic anions favor unstructured conformation, whereas kosmotropic ..
- Transition metal salts-catalyzed aza-Michael reactions of enones with carbamatesShu Kobayashi
Graduate School of Pharmaceutical Science, The University of Tokyo and CREST, Japan Science and Technology Corporation JST, Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Org Lett 4:1319-22. 2002Several transition metal salts were found to catalyze aza-Michael reactions of enones with carbamates efficiently. The catalytic activity was strongly dependent on the nature of the metal salts...
- Chitosan and its salts for mucosal and transmucosal deliveryMaria Cristina Bonferoni
University of Pavia, Department of Pharmaceutical Chemistry, Pavia, Italy
Expert Opin Drug Deliv 6:923-39. 2009This review considers the application of chitosan and its salts in the delivery of drugs intended to act locally towards diseases of the mucosa itself (mucosal delivery), and to undergo systemic absorption by means of transmucosal routes ..
- Dominant role of prostaglandin E2 EP4 receptor in furosemide-induced salt-losing tubulopathy: a model for hyperprostaglandin E syndrome/antenatal Bartter syndromeRolf M Nusing
Institute of Clinical Pharmacology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, Frankfurt 60590, Germany
J Am Soc Nephrol 16:2354-62. 2005..In summary, these findings demonstrate that the EP4 receptor mediates PGE2-induced renin secretion and that EP1, EP3, and EP4 receptors all contribute to enhanced PGE2-mediated salt and water excretion in the HPS/aBS model...
- Atypical effect of salts on the thermodynamic stability of human prion proteinAdrian C Apetri
Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio 44106, USA
J Biol Chem 278:22187-92. 2003..Previous studies indicate that salts promote conformational conversion of the recombinant prion protein into a PrPSc-like form...
- Correlation between thermal aggregation and stability of lysozyme with salts described by molar surface tension increment: an exceptional propensity of ammonium salts as aggregation suppressorAtsushi Hirano
Institute of Applied Physics, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki, 305 8573, Japan
Protein J 26:423-33. 2007..This paper investigates the process of thermal aggregation of lysozyme in the presence of various types of salts. The simple law was found; the aggregation rate of lysozyme increased with increasing melting temperature of the ..
- An equilibrium thermodynamic model of the sequestration of calcium phosphate by casein micelles and its application to the calculation of the partition of salts in milkCarl Holt
Hannah Research Institute, KA6 5HL Ayr, UK
Eur Biophys J 33:421-34. 2004..From this model, a method of calculating the partition of milk salts into diffusible and non-diffusible fractions is obtained...
- Electrophysiological responses to salts from antennal chaetoid taste sensilla of the ground beetle Pterostichus aethiopsEnno Merivee
Estonian Agricultural University, Institute of Plant Protection, 64 Kreutzwaldi Street, 51014 Tartu, Estonia
J Insect Physiol 50:1001-13. 2004..1797) (Coleoptera, Carabidae) respond to salts, the three sensory cells, A-, B- and C-cells, producing action potentials that are distinguished by differences in ..
- Effects of engineered salt bridges on the stability of subtilisin BPN'C R Erwin
Corporate Research Division, Procter and Gamble Company, Miami Valley Laboratories, Cincinnati, OH 45239 8707
Protein Eng 4:87-97. 1990....
- Mesomorphic imidazolium salts: new vectors for efficient siRNA transfectionWilliam Dobbs
Institut de Physique et Chimie des Materiaux de Strasbourg, UMR 7504, CNRS Universite de Strasbourg, BP 43, 23 rue du Loess, F 67034 Strasbourg Cedex 2, France
J Am Chem Soc 131:13338-46. 2009..The two series of salts possess a rich thermotropic mesomorphism, chain-length dependent...
- A rigidifying salt-bridge favors the activity of thermophilic enzyme at high temperatures at the expense of low-temperature activitySonia Y Lam
School of Life Sciences, Centre for Protein Science and Crystallography, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
PLoS Biol 9:e1001027. 2011..Here we employed a thermophilic acylphosphatase from Pyrococcus horikoshii and its homologous mesophilic acylphosphatase from human as a model to study how local rigidity of an active-site residue affects the enzymatic activity...
- Chitosans as nasal absorption enhancers of peptides: comparison between free amine chitosans and soluble saltsP Tengamnuay
Department of Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
Int J Pharm 197:53-67. 2000A total of three free amine chitosans (CS J, CS L and CS H) and two soluble chitosan salts (CS G and CS HCl) were evaluated for their efficacy and safety as nasal absorption enhancers of peptides based on in situ nasal perfusion and ..
- Antimicrobial activities and cellular responses to natural silicate clays and derivatives modified by cationic alkylamine saltsShan Hui Hsu
Institute of Polymer Science and Engineering, National Taiwan University, Taipei 10617 Taiwan, Republic of China
ACS Appl Mater Interfaces 1:2556-64. 2009..The derivatives of NSP (NSP-S) which were modified by C18-fatty amine salts via ionic exchange association exhibited the highest antibacterial activity in the aqueous state among all clays...
- Thermotoga maritima ribonuclease III. Characterization of thermostable biochemical behavior and analysis of conserved base pairs that function as reactivity epitopes for the Thermotoga 23S rRNA precursorLilian Nathania
Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA
Biochemistry 49:7164-78. 2010..These results indicate the conservation, across a broad phylogenetic distance, of positive and negative determinants of reactivity of bacterial RNase III substrates...
- Thermostable variants constructed via the structure-guided consensus method also show increased stability in salts solutions and homogeneous aqueous-organic mediaE Vazquez-Figueroa
School of Chemical and Biomolecular Engineering, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332 0363, USA
Protein Eng Des Sel 21:673-80. 2008..method also showed improved stability in solutions with high concentrations of kosmotropic and chaotropic salts and water-miscible organic solvents...
- Relationship between apatite-forming ability and mechanical properties of bioactive PMMA-based bone cement modified with calcium salts and alkoxysilaneAtsushi Sugino
Graduate School of Engineering, Nagoya University, Furo cho, Chikusa ku, Nagoya 464 8603, Japan
J Mater Sci Mater Med 19:1399-405. 2008..revealed that modification using gamma-methacryloxypropyltrimethoxysilane (MPS) and water-soluble calcium salts such as calcium acetate and calcium hydroxide was effective for providing the PMMA-based bone cement with apatite-..
- Systematic study of hydration patterns of phosphoric(V) acid and its mono-, di-, and tripotassium salts in aqueous solutionMaciej Smiechowski
Department of Physical Chemistry, Chemical Faculty, Gdansk University of Technology, Narutowicza 11 12, 80 233 Gdansk, Poland
J Phys Chem B 113:7650-61. 2009..Further interpretation of the energetic and structural properties of hydrating water is enabled by calculating intermolecular interaction energy of water and probability distributions for interatomic oxygen-oxygen distance...
- Haloarchaeal diversity in 23, 121 and 419 MYA saltsJ S Park
Canadian Institute for Advanced Research, Program in Integrated Microbial Diversity, and Department of Biology, Dalhousie University, Halifax, Canada
Geobiology 7:515-23. 2009..The DNA demonstrates that unknown haloarchaea and the Halobacterium were key components in ancient hypersaline environments. Halorubrum and Haloarcula appear to be a dominant group in relatively modern hypersaline habitats...
- Transgenic expression of MYB15 confers enhanced sensitivity to abscisic acid and improved drought tolerance in Arabidopsis thalianaZhenhua Ding
State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
J Genet Genomics 36:17-29. 2009....
- Synthesis and antimicrobial properties of imidazolium and pyrrolidinonium saltsD Demberelnyamba
Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, South Korea
Bioorg Med Chem 12:853-7. 2004..Three different series of quaternary imidazolium and pyrrolidinonium salts were synthesized: series A (1-alkyl-3-methylimidazolium chlorides and bromides); series B (1-alkyl-2-methyl-3-..
- Reversibility of beta-amyloid self-assembly: effects of pH and added salts assessed by fluorescence photobleaching recoveryNadia J Edwin
Department of Chemistry and Macromolecular Studies Group, Louisiana State University, Baton Rouge, 70803, USA
Biomacromolecules 11:341-7. 2010..Oligomeric aggregates were found by fluorescence photobleaching recovery to respond readily to pH and salt conditions. Changing these external cues leads to formation or disassembly of aggregates smaller than 100 nm within minutes...
- Changes in phosphatidylcholine headgroup tilt and water order induced by monovalent salts: molecular dynamics simulationsJonathan N Sachs
Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Biophys J 86:3772-82. 2004The association between monovalent salts and neutral lipid bilayers is known to influence global bilayer structural properties such as headgroup conformational fluctuations and the dipole potential...
- Influence of salts and phenolic compounds on olive mill wastewater detoxification using superabsorbent polymersL C Davies
Centre of Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisbon, Portugal
Bioresour Technol 95:259-68. 2004..the absorption capacity was evaluated for the principal absorption-inhibition constituent of OMW, mineral salts and for phytotoxic-components, the phenolic compounds...
- Effect of ethanolamine salts and enhancers on the percutaneous absorption of piroxicam from a pressure sensitive adhesive matrixHyun-Ah Cheong
College of Pharmacy, Chosun University, 375 Seosuk-dong, Dong-gu, Gwangju 501-759, South Korea
Eur J Pharm Sci 18:149-53. 2003..studied the effect of permeation enhancers on the skin permeation of piroxicam or piroxicam-ethanolamine (PX-EA) salts from an acrylic adhesive matrix...
- Production of optically pure D-lactic acid in mineral salts medium by metabolically engineered Escherichia coli W3110Shengde Zhou
Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida 32611, USA
Appl Environ Microbiol 69:399-407. 2003..These strains (SZ40, SZ58, and SZ63) require only mineral salts as nutrients and lack all plasmids and antibiotic resistance genes used during construction...
- Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channelsKimberley B Craven
Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195-7290, USA
J Gen Physiol 124:663-77. 2004..Discovering that one portion of the COOH terminus, the CNBD, can be in the activated configuration while the other portion, the C-linker, is not activated has lead us to suggest a novel modular gating scheme for HCN and CNG channels...
- Conformation of Napin (Brassica juncea) in salts and monohydric alcohols: contribution of electrostatic and hydrophobic interactionsT C Jyothi
Department of Protein Chemistry and Technology, Central Food Technological Research Institute, Mysore, India
J Agric Food Chem 55:4229-36. 2007..These studies indicate that the structure of napin, which is hydrophilic in nature, is stabilized by electrostatic interactions, in addition to disulfide linkages...
- Occupational hypersensitivity to metal salts, including platinum, in the secondary industryA Cristaudo
Servizio di Allergologia, Istituto San Gallicano, IRCCS, Rome, Italy
Allergy 60:159-64. 2005..Our aim was to determine the prevalence and the clinical characteristics of hypersensitivity to platinum salts and to other elements of the platinum group...
- Recent advances in engineering plant tolerance to abiotic stress: achievements and limitationsBasia Vinocur
The Robert H Smith Institute of Plant Sciences and Genetics in Agriculture and the Otto Warburg Center for Agricultural Biotechnology, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
Curr Opin Biotechnol 16:123-32. 2005..Unraveling additional stress-associated gene resources, from both crop plants and highly salt- and drought-tolerant model plants, will enable future molecular dissection of salt-tolerance mechanisms in important crop plants...
- Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptorsCeline E Riera
Nestle Research Center, P O Box 44, CH 1000 Lausanne 26, Switzerland
Am J Physiol Regul Integr Comp Physiol 293:R626-34. 2007..We also found that TRPV1 receptors are activated by CuSO(4), ZnSO(4), and FeSO(4), three salts known to produce a metallic taste sensation...
- Production of poly-beta-hydroxybutyrate (PHB) by Vibrio spp. isolated from marine environmentChih Ching Chien
Graduate School of Biotechnology and Bioinformatics, Yuan Ze University, 135 Yuan Tung Road, Chung Li 320, Taiwan
J Biotechnol 132:259-63. 2007..V. natriegens has the shortest generation time (9.8 min) of any bacterium and this characteristic may be an exploitable trait for the industrial production of PHB...
- DNA-mediated phase behavior of microsphere suspensionsPaul L Biancaniello
Department of Physics and Astronomy, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA
Langmuir 23:2688-93. 2007..Computational analysis assigns a 4 kBT attraction between pairs of complementary microspheres at the destabilizing fluid --> fluid + aggregates transition...
- Transport of antimony salts by Arabidopsis thaliana protoplasts over-expressing the human multidrug resistance-associated protein 1 (MRP1/ABCC1)Landry Gayet
CEA Cadarache, DSV-DEVM--LEMS, , 13108 St Paul lez Durance, France
FEBS Lett 580:6891-7. 2006..In these plants, expression of MRP1 did not increase plant resistance to antimony salts (Sb(III)), a classical glutathione-conjugate substrate of MRP1...
- Aminodifluorosulfinium tetrafluoroborate salts as stable and crystalline deoxofluorinating reagentsFrancis Beaulieu
OmegaChem Inc, 8800 Boul De la Rive Sud, Levis, QC G6V 9H1, Canada
Org Lett 11:5050-3. 2009Aminodifluorosulfinium tetrafluoroborate salts were found to act as efficient deoxofluorinating reagents when promoted by an exogenous fluoride source and, in most cases, exhibited greater selectivity by providing less elimination ..
- Betaine tripled the volumetric productivity of D(-)-lactate by Escherichia coli strain SZ132 in mineral salts mediumS Zhou
Department of Biological Sciences, Northern Illinois University, DeKalb, IL 60115, USA
Biotechnol Lett 28:671-6. 2006..productivity, and D-lactate tolerance in Escherichia coli B strain SZ132 during batch fermentation in mineral salts medium with 10% (w/v) sugar...
- Fermentation of 12% (w/v) glucose to 1.2 M lactate by Escherichia coli strain SZ194 using mineral salts mediumS Zhou
Department of Biological Sciences, Northern Illinois University, DeKalb, IL 60115, USA
Biotechnol Lett 28:663-70. 2006..B, strain SZ194, was developed that produces over 1 M D-lactate from glucose (or sucrose) in 72 h using mineral salts medium supplemented with 1 mM: betaine in simple anaerobic fermentations. Rates and yields were highest at pH 7.5...
- A DEAD-box protein alone promotes group II intron splicing and reverse splicing by acting as an RNA chaperoneSabine Mohr
Institute for Cellular and Molecular Biology, Department of Chemistry and Biochemistry and Section of Molecular Genetics and Microbiology, School of Biological Sciences, University of Texas, Austin, TX 78712, USA
Proc Natl Acad Sci U S A 103:3569-74. 2006..More generally, our results provide additional evidence for the widespread role of RNA chaperones in folding cellular RNAs...
- Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNADebra McLaggan
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK
BMC Biotechnol 6:6. 2006Haplosclerid marine sponges produce pore forming polyalkylpyridinium salts (poly-APS), which can be used to deliver macromolecules into cells...
- Morphology of actin assemblies in response to polycation and saltsHyuck Joon Kwon
Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan, and SORST, JST, Sapporo, 060-0810, Japan
Biomacromolecules 6:3005-9. 2005..Our results indicate that the semiflexible polyelectrolyte nature of F-actins is important for controlling the morphology and growth of actin architectures in cells...
- Identification of conserved prolyl residue important for transport activity and the substrate specificity range of yeast plasma membrane Na+/H+ antiportersOlga Kinclova-Zimmermannova
Department of Membrane Transport, Institute of Physiology AS CR, Prague 4, 142 20, Czech Republic
J Biol Chem 280:30638-47. 2005..This is the first evidence that a non-polar amino acid residue is important for the substrate specificity and activity of yeast Nha antiporters...
- Facile microwave-assisted synthesis of cyclic amidinium saltsAdila Aidouni
Center for Education and Research on Macromolecules, Institut de Chimie B6a, Universite de Liege, Sart Tilman par 4000 Liège, Belgium
J Comb Chem 10:886-92. 2008The cyclization of N,N'-dialkyl or diaryl ethane-1,2-diamines or propane-1,3-diamines with inorganic ammonium salts and orthoesters proceeds briskly under microwave irradiation to afford the corresponding imidazolinium or ..
- Composite formation from hydroxyapatite with sodium and potassium salts of polyphosphazeneY E Greish
Intercollege Materials Research Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
J Mater Sci Mater Med 16:613-20. 2005..In the presence of 1% by weight of polyphosphazenes, composites comprised of SHAp and calcium cross-linked polymer salts were formed. Thus a mechanism for binding between polymer chains was established...
- Evaluation of chitosan salts as non-viral gene vectors in CHO-K1 cellsWanlop Weecharangsan
Faculty of Pharmacy, Silpakorn University, Nakhonpathom 73000, Thailand
Int J Pharm 348:161-8. 2008The aim of this study was to investigate chitosan/DNA complexes formulated with various chitosan salts (CS) including chitosan hydrochloride (CHy), chitosan lactate (CLa), chitosan acetate (CAc), chitosan aspartate (CAs) and chitosan ..
- Alkynyliodonium salts in organic synthesis. Development of a unified strategy for the syntheses of (-)-agelastatin A and (-)-agelastatin BKen S Feldman
Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
J Org Chem 67:7096-109. 2002..Subsequent manipulations delivered debromoagelastatin, which served as a precursor to both agelastatin A and agelastatin B. Alkylidenecarbene insertion chemoselectivity issues were explored en route to the final targets...
- A spectroscopic study of the fluorescence quenching interactions between biomedically important salts and the fluorescent probe merocyanine 540A Adenier
, , UPRESA 7086, , France
Spectrochim Acta A Mol Biomol Spectrosc 58:543-51. 2002The effects of several biologically important inorganic salts, including NaCl, NaI, NaBr, KCl, MgCl2, MgSO4 and CaCl2 on the electronic absorption and fluorescence spectra of Merocyanine 540 (MC-540) have been investigated in aqueous ..
- Temperature and amiloride alter taste nerve responses to Na+, K+, and NH+4 salts in ratsR F Lundy
Department of Psychology, Florida State University, Tallahassee 32306 1051, USA
Brain Res 744:309-17. 1997..Taste nerve responses to all Na+ and NH4+ salts, but not K/ salts, were significantly smaller at 25 degrees C than at 35 degrees C...
- Microcalorimetric studies on the interaction mechanism between proteins and hydrophobic solid surfaces in hydrophobic interaction chromatography: effects of salts, hydrophobicity of the sorbent, and structure of the proteinF Y Lin
Department of Chemical Engineering, National Central University, Chung-Li, Taiwan
Anal Chem 73:3875-83. 2001This study examines the effects of different salts as well as the influence of the relative hydrophobicities of different sorbents on the adsorption processes of proteins in hydrophobic interaction chromatography (HIC)...
- Cyclodextrin complexes of salts of acidic drugs. Thermodynamic properties, structural features, and pharmaceutical applicationsE Redenti
R and D Department, Chiesi Farmaceutici s p a, Via Palermo 26 A, 43100 Parma, Italy
J Pharm Sci 90:979-86. 2001....
- The Nha1 antiporter of Saccharomyces cerevisiae mediates sodium and potassium effluxM A Bañuelos
Laboratoire de Microbiologie et de Genetique, Université Louis Pasteur CNRS, Strasbourg, France
Microbiology 144:2749-58. 1998..Both systems have a complementary action to maintain the intracellular steady-state concentration of K+ and Na+...
- Micronuclei assay and FISH analysis in human lymphocytes treated with six metal saltsL Migliore
Dipartimento di Scienze dell Uomo e dell Ambiente, Universita di Pisa, Pisa, Italy
Environ Mol Mutagen 34:279-84. 1999..In this investigation, Al (III), Cd (II), Hg (II), Sb (V), Te (VI), and Tl (I) salts were considered...
- Effect of salts on the functional properties of benniseed (Sesamum radiatum) seed flourH N Ogungbenle
Chemistry Department, University of Ado-Ekiti, P.M.B. 5363, Ado-Ekiti, Nigeria
Int J Food Sci Nutr 53:5-14. 2002The effects of salts, KCl, NaCl, K2SO4, Na2SO4 and CH3COONa on the functional properties of benniseed (Sesamum radiatum) flour were studied...
- Cell signaling under salt, water and cold stressesJ K Zhu
Department of Plant Sciences, University of Arizona, Tucson, Arizona 85721, USA
Curr Opin Plant Biol 4:401-6. 2001..Molecular analysis revealed a transcriptional cascade in cold-regulated gene expression...
- Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 A resolution structures of the wild type and a mutant of malate dehydrogenase from Haloarcula marismortuiS B Richard
Institut de Biologie Structurale, CEA CNRS, 41 Avenue des Martyrs, F 38027 Grenoble Cedex 1, France
Biochemistry 39:992-1000. 2000....
- Organic acids and their salts as dipping solutions to control listeria monocytogenes inoculated following processing of sliced pork bologna stored at 4 degrees C in vacuum packagesJ Samelis
Center for Red Meat Safety, Department of Animal Sciences, Colorado State University, Fort Collins 80523, USA
J Food Prot 64:1722-9. 2001..This study evaluated aqueous dipping solutions of organic acids (2.5 or 5% lactic or acetic acid) or salts (2...
- The kinetics of the alkaline degradation of daptomycinW Muangsiri
Division of Pharmaceutics, College of Pharmacy, The University of Iowa, Iowa City, IA 52242, USA
J Pharm Sci 90:1066-75. 2001..2 eu. The positive primary salt effect was observed with negative deviation at high concentration of salt. The magnitude of the salt effect depended on salt identities in the order sodium < potassium < calcium chloride...
- Noise in solid-state nanoporesR M M Smeets
Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands
Proc Natl Acad Sci U S A 105:417-21. 2008..Finally, we use these results to compute the signal-to-noise ratio for DNA translocation for different salt concentrations and nanopore diameters, yielding the parameters for optimal detection efficiency...
- An analysis of electrical conductances of aqueous solutions of polybasic organic acids. Benzenehexacarboxylic (mellitic) acid and its neutral and acidic saltsAlexander Apelblat
Department of Chemical Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
J Phys Chem B 110:8893-906. 2006..numerical procedure is illustrated by the case of benzenehexacarboxylic (mellitic) acid and its neutral and acidic salts. From conductivity measurements of mellitic acid and its salts, performed in dilute aqueous solutions in the 278...
- Interaction of brine concentration, brine temperature, and presalting on salt penetration in Ragusano cheeseC Melilli
CoRFiLaC, Regione Siciliana, 97100 Ragusa, Italy
J Dairy Sci 89:1420-38. 2006..The increase in yield needs to be balanced against the risk of growth of undesirable bacteria in the 18%B and the creation of another cheese quality defect...
- Characterization of the ion transport activity of the budding yeast Na+/H+ antiporter, Nha1p, using isolated secretory vesiclesRyuichi Ohgaki
Department of Biological Sciences, Graduate School of Science, Osaka University, Machikaneyama, Toyonaka, Osaka 560 0043, Japan
Biochim Biophys Acta 1712:185-96. 2005..The ion selectivity and the stoichiometry suggest a unique physiological role of Nha1p which is distinct from that of other known Na+/H+ antiporters...
- Reassembly of active caspase-3 is facilitated by the propeptideBrett Feeney
Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina 27695 7622, USA
J Biol Chem 280:39772-85. 2005..In addition, the effects of salts on caspase structure have not been examined...
- Salt tolerance of archaeal extremely halophilic lipid membranesBoris Tenchov
Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL 60208, USA
J Biol Chem 281:10016-23. 2006....
- High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptideFrancois Hoh
Centre de Biochimie Structurale, UMR5048 CNRS Université Montpellier I, UMR554 INSERM Université Montpellier I, Faculte de Pharmacie, 15 Avenue Charles Flahault, BP 14491, 34093 Montpellier Cedex 5, France
Biochemistry 43:15154-68. 2004..Therefore, it appears to be likely that the prosequence does assist the ET-1 folding in a chaperone-like manner before successive cleavages that yield the bioactive ET-1 hormone...
- The crystal structure of indoleglycerol-phosphate synthase from Thermotoga maritima. Kinetic stabilization by salt bridgesThorsten Knöchel
Division of Structural Biology, Biozentrum, University Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
J Biol Chem 277:8626-34. 2002..This observation is consistent with a protein unfolding mechanism where the simultaneous breakdown of all salt bridges is the rate-determining step...
- Novel self-assembly of amphiphilic copolymers into nanotubes: characterization by small-angle neutron scatteringC Malardier-Jugroot
Department of Chemistry, McGill University, Montreal, Canada
Langmuir 21:10179-87. 2005..When more salt is added, the size of the association decreases, and the structure is altered. The association was found to be independent of temperature and therefore is very stable...
- Cyanine dyes as intercalating agents: kinetic and thermodynamic studies on the DNA/Cyan40 and DNA/CCyan2 systemsTarita Biver
Dipartimento di Chimica e Chimica Industriale, , Pisa, Italy
Biophys J 89:374-83. 2005..Absorption spectra reveal that both dyes tend to self-aggregate; the kinetics of CCyan2 self-aggregation is studied by T-jump relaxation and the results are interpreted in terms of dimer formation...
- Growth physiology and competitive interaction of obligately chemolithoautotrophic, haloalkaliphilic, sulfur-oxidizing bacteria from soda lakesDimitry Y Sorokin
Institute of Microbiology, Russian Academy of Sciences, Prospect 60 let Octyabrya 7 2, 117811 Moscow, Russia
Extremophiles 7:195-203. 2003..33 h(-1)) out-competed Thioalkalivibrio strains (mu(max)=0.15 h(-1)) at D>0.02 h(-1). The overall results suggest that Thioalkalimicrobium and Thioalkalivibrio represent two different ecological strategies...
- Thermodynamic studies of the core histones: stability of the octamer subunits is not altered by removal of their terminal domainsV Karantza
Department of Biology, The Johns Hopkins University, Baltimore, Maryland 21218
Biochemistry 40:13114-23. 2001....
- Salt-dependent monomer-dimer equilibrium of bovine beta-lactoglobulin at pH 3K Sakurai
Institute for Protein Research, Osaka University, Yamadaoka 3-2, Suita, Osaka 565-0871, Japan
Protein Sci 10:2325-35. 2001..bovine beta-lactoglobulin assumes a monomeric native structure at pH 3 in the absence of salt, the addition of salts stabilizes the dimer...
- Theory of electrostatically regulated binding of T4 gene 32 protein to single- and double-stranded DNAIoulia Rouzina
Department of Biochemistry Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA
Biophys J 89:1941-56. 2005..The predictions of our model quantitatively describe the large body of thermodynamic and kinetic data from bulk and single molecule experiments on gp32 and *I binding to single-stranded nucleic acids...
- [Effect of thermolability of milk proteins on ion distribution in two-phase system of skimmed milk-water-salt]N K Genkina
Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 117813 Russia
Prikl Biokhim Mikrobiol 37:379-82. 2001..The increase was caused by denaturation of milk whey proteins and formation of protein-protein and protein-carbohydrate aggregates. Preheating did not influence the distribution of nitrate ions in the two-phase system...
- Binding of charged ligands to macromolecules. Anomalous salt dependenceFernando Luís B da Silva
Department of Theoretical Chemistry and Department of Biophysical Chemistry, Lund University, P O Box 124, S 22100 Lund, Sweden
J Phys Chem B 109:2007-13. 2005..These results are also relevant for the interpretation of competition studies often used in the case of strong ligand binding...
- Phase behavior and charge regulation of weak polyelectrolyte grafted layersPeng Gong
Department of Chemistry, Purdue University, West Lafayette, IN 47907 1393, USA
Phys Rev Lett 98:018302. 2007..The range of stability of the film with regard to polymer surface coverage, temperature, bulk pH and salt concentration is demonstrated...
- Formation of a wrapped DNA-protein interface: experimental characterization and analysis of the large contributions of ions and water to the thermodynamics of binding IHF to H' DNAKirk A Vander Meulen
Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
J Mol Biol 377:9-27. 2008..7+/-0.4 at constant KCl activity, indicating the net release of ca. 150 H(2)O molecules from anionic surface...
- Structure, solubility, screening, and synthesis of molecular saltsSimon N Black
Process Engineering Group, PR and D, AstraZeneca, Macclesfield, Cheshire, SK10 2NA, United Kingdom
J Pharm Sci 96:1053-68. 2007The preparation of molecular salts as potential delivery vehicles for pharmaceutically active compounds is more common than current appreciation of the phenomena governing the solubility and isolation of salts suggests...
- Effects of monovalent anions of the hofmeister series on DPPC lipid bilayers Part II: modeling the perpendicular and lateral equation-of-stateE Leontidis
Department of Chemistry, University of Cyprus, Nicosia, Cyprus
Biophys J 93:1591-607. 2007....
- Liquid-liquid phase transition of protein aqueous solutions isothermally induced by protein cross-linkingYing Wang
Department of Chemistry, Texas Christian University, Fort Worth, Texas 76129, USA
Langmuir 24:2799-807. 2008..It also provides guidance for the development of new methods based on mild experimental conditions for the preparation of protein-based materials...
- HMGA1a protein unfolds or refolds synthetic DNA-chromophore hybrid polymers: a chaperone-like behaviorWei Wan
Department of Chemistry, Washington State University, Pullman, WA 99164, USA
Chembiochem 9:304-11. 2008..The unfolding mechanisms and the binding stoichiometry of protein-hybrid polymers depended on the sequence of the synthetic polymers...
- Investigation of salt properties with electro-acoustic measurements and their effect on dynamic binding capacity in hydrophobic interaction chromatographyEgbert Müller
Tosoh Bioscience GmbH, Zettachring 6, Stuttgart, Germany
J Chromatogr A 1177:215-25. 2008....
- Nanomaterials for efficiently lowering the freezing point of anti-freeze coolantsHaiping Hong
South Dakota School of Mines and Technology, Rapid City, SD 57701, USA
J Nanosci Nanotechnol 7:3180-4. 2007....
- Evaluation of change in water quality with strong acid exchanger effluent conductivityS S Bagchi
Koradi Thermal Power Station, Koradi, Maharashtra, India
J Environ Sci Eng 49:207-10. 2007..Therefore, an attempt has been made to evaluate the change in water quality on the basis of Strong Acid Cation Exchanger Effluent Conductivity and its impact on demineralised water treatment plant...
- Microwave heating of water, ice, and saline solution: molecular dynamics studyMotohiko Tanaka
Coordinated Research Center, National Institute for Fusion Science, Toki 509 5292, Japan
J Chem Phys 126:034509. 2007..Dilute salt water is significantly more heated than pure water because of the field-induced motion of salt ions, especially that of large-size ions, by the microwave electric field and energy transfer to water molecules by collisions...
- Effects of concentration, relative permittivity, and temperature on the solution behavior of sodium carboxymethylcellulose as probed by electrical conductivityPrabir Nandi
Deparment of Chemistry, North Bengal University, Darjeeling 734430, India
J Phys Chem B 109:3238-42. 2005..The effects of the temperature and relative permittivity of the medium on the equivalent conductivity as well as on the fraction of uncondensed counterions were also investigated...
- Atomically detailed simulations of concentrated protein solutions: the effects of salt, pH, point mutations, and protein concentration in simulations of 1000-molecule systemsSean R McGuffee
Department of Biochemistry, University of Iowa, Iowa City, Iowa 52242, USA
J Am Chem Soc 128:12098-110. 2006....
- A molecular-thermodynamic model for the interactions between globular proteins in aqueous solutions: applications to bovine serum albumin (BSA), lysozyme, alpha-chymotrypsin, and immuno-gamma-globulins (IgG) solutionsLin Jin
Department of Chemical Engineering, Tsinghua University, Beijing 100084, People's Republic of China
J Colloid Interface Sci 304:77-83. 2006..At high ionic strength, the charge inversions of protein molecules should be taken into account...
- pK(a) values for side-chain carboxyl groups of a PGB1 variant explain salt and pH-dependent stabilityStina Lindman
Department of Biophysical Chemistry, Lund University, Chemical Center, SE 22100 Lund, Sweden
Biophys J 92:257-66. 2007..We show also that (13)C backbone carbonyl data can be used to study electrostatic coupling in proteins and provide specific information on hydrogen bonding and electrostatic potential at nontitrating sites...
- Control of acidity development on solid sulfur due to bacterial actionFrancesco Crescenzi
EniTecnologie, Via E. Ramarini 32, Monterotondo, RM, Italy
Environ Sci Technol 40:6782-6. 2006..Possible ways to exploit the inhibitory effect to prevent the generation of acidity from sulfur storage blocks are suggested...
- The alternatively folded state of the antibody C(H)3 domainM J Thies
, , Lichtenbergstr. 4, Garching, 85747, Germany
J Mol Biol 309:1077-85. 2001..The defined oligomeric structure of C(H)3 at pH 2 seems to be a prerequisite for the cooperative unfolding transitions...
- Kinetic model for salt-induced protein deactivationJames M Broering
School of Chemical and Biomolecular Engineering, Parker H Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332 0363, USA
J Phys Chem B 112:12768-75. 2008A quantitative description of the influence of salts and buffer components on the degradation of proteins is important for the shelf life of pharmaceuticals and operating life of biocatalysts but is currently lacking...
- The mutations Lys 114 --> Gln and Asp 126 --> Asn disrupt an intersubunit salt bridge and convert Listeria innocua Dps into its natural mutant Listeria monocytogenes Dps. Effects on protein stability at Low pHGiuliano Bellapadrona
Dipartimento di Scienze Biochimiche A Rossi Fanelli, Universita La Sapienza, Rome, Italy
Proteins 66:975-83. 2007..In contrast, the salt-bridge between Lys 114 and Asp 126 characteristic of L. innocua Dps is most likely abolished due to protonation of Asp 126...
- Protein phase behavior and crystallization: effect of glycerolH Sedgwick
Scottish Universities Physics Alliance SUPA, School of Physics, The University of Edinburgh, Mayfield Road, Edinburgh EH9 3JZ, Scotland
J Chem Phys 127:125102. 2007..Quantifying the interprotein interaction by the second virial coefficient, B(2), we find a universal crystallization boundary for all glycerol concentrations...
- Conformational and thermodynamic characterization of the molten globule state occurring during unfolding of cytochromes-c by weak salt denaturantsShabir H Qureshi
Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi - 110 025, India
Biochemistry 42:1684-95. 2003..92 +/- 0.02 kcal mol(-1) K(-1) and 0.41 +/- 0.01 kcal mol(-1) K(-1), respectively. These measurements suggested that about 30% of the hydrophobic groups in the molten globule state are not accessible to the water...
- Diet and Gastrointestinal Cancer Risk in African Americans and Rural AfricansSTEPHEN JD O apos KEEFE; Fiscal Year: 2010..producing bacteria in AAs which are stimulated by high animal fat diets to produce carcinogenic secondary bile salts. In contrast, a high resistant starch diet stimulates mucosal-protective Lactobacillus species were, indeed, found ..
- Au/Pt Catalysis in the Synthesis of Elaborate N-Heterocycles: Methodology DevelopLiming Zhang; Fiscal Year: 2009..Au catalysis has attracted tremendous attention lately due to the exceptional capacities of Au salts/complexes in activating alkynes/allenes/alkenes. Pt catalysts, mostly PtCl2, have shown similar reactivities...
- Au/Pt Catalysis in the Synthesis of Elaborate N-Heterocycles: Methodology DevelopLiming Zhang; Fiscal Year: 2010..Au catalysis has attracted tremendous attention lately due to the exceptional capacities of Au salts/complexes in activating alkynes/allenes/alkenes. Pt catalysts, mostly PtCl2, have shown similar reactivities...
- Reasons for poor durability of resin-dentin bondsDavid H Pashley; Fiscal Year: 2010..We noted that CHX contains biguanide groups that form acidic addition salts with a cationic charge delocated over the five neighboring secondary amine nitrogen atoms of the biguanides...
- Reasons for poor durability of resin-dentin bondsDavid Pashley; Fiscal Year: 2009..We noted that CHX contains biguanide groups that form acidic addition salts with a cationic charge delocated over the five neighboring secondary amine nitrogen atoms of the biguanides...
- EXPLT BASIS FOR ALCOHOL AND COCAINE STROKES ROLE OF MG2+Burton Altura; Fiscal Year: 1993..Preliminary, in-situ experiments indicate that administration of Mg salts results in dose-dependent inhibition of the alcohol and cocaine-induced cerebral microvascular spasms and ..
- DEVELOPING SOLUTES AS STRUCTURAL/MECHANISTIC PROBES OF PROTEIN-DNA INTERACTIONSM Thomas Record; Fiscal Year: 2010Biochemically-significant small molecules (Hofmeister salts, osmolytes, denaturants, collectively referred to as solutes) exert often large, specific effects on fundamental biological processes involving proteins and nucleic acids (e.g...
- DEVELOPING SOLUTES AS STRUCTURAL/MECHANISTIC PROBES OF PROTEIN-DNA INTERACTIONSM Thomas Record; Fiscal Year: 2011DESCRIPTION (provided by applicant): Biochemically-significant small molecules (Hofmeister salts, osmolytes, denaturants, collectively referred to as solutes) exert often large, specific effects on fundamental biological processes ..
- NEURAL CONTROL OF THE GALLBLADDERGary Mawe; Fiscal Year: 2009..Recent reports suggest that decreased gallbladder motility is caused by elevated cholesterol and hydrophobic salts in the bile, and that ensuing inflammation and impairments in gallbladder emptying lead to stone formation...
- NEURAL CONTROL OF THE GALLBLADDERGary M Mawe; Fiscal Year: 2010..Recent reports suggest that decreased gallbladder motility is caused by elevated cholesterol and hydrophobic salts in the bile, and that ensuing inflammation and impairments in gallbladder emptying lead to stone formation...
- SENSORY CODING IN TASTEDavid Smith; Fiscal Year: 2000..Adapted From The Investigator s Abstract): Recent studies have provided insights into the transduction of sodium salts and acids by taste receptor cells and the organization of chemical sensitivities in neurons of the afferent ..
- DEVELOPMENT OF THE SENSE OF TASTECharlotte Mistretta; Fiscal Year: 1993..of the taste system in mammals, there is a striking increase in neural responsiveness to NaCl compared to other salts. Developmental differences in salt taste responses are accompanied by neural rearrangements that alter number of ..