talc

Summary

Summary: Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)

Top Publications

  1. ncbi Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion
    Carolyn M Dresler
    Head, Tobacco Unit, International Agency for Research on Cancer, Lyon, France
    Chest 127:909-15. 2005
  2. ncbi Iodopovidone: an inexpensive and effective agent for chemical pleurodesis
    Ritesh Agarwal
    Lung Cancer 55:253-4. 2007
  3. ncbi Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: the TIME2 randomized controlled trial
    Helen E Davies
    Department of Respiratory Medicine, University Hospital of Wales, Cardiff, Wales
    JAMA 307:2383-9. 2012
  4. ncbi Carcinogenicity of carbon black, titanium dioxide, and talc
    Robertv Baan
    Lancet Oncol 7:295-6. 2006
  5. ncbi Inflammatory parameters after pleurodesis in recurrent malignant pleural effusions and their predictive value
    Valiant Ukale
    Department of Medicine, Thoracic Clinics, Karolinska sjukhuset, Stockholm S 171 76, Sweden
    Respir Med 98:1166-72. 2004
  6. ncbi Pleural mesothelial cells mediate inflammatory and profibrotic responses in talc-induced pleurodesis
    Milena Marques P Acencio
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Lung 185:343-8. 2007
  7. ncbi Prospective randomized trial of silver nitrate vs talc slurry in pleurodesis for symptomatic malignant pleural effusions
    Marcello da Silveira Paschoalini
    Perola Byington Hospital, Sao Paulo, Brazil
    Chest 128:684-9. 2005
  8. ncbi Black Lucques olives prevented bone loss caused by ovariectomy and talc granulomatosis in rats
    Caroline Puel
    Unité des Maladies Métaboliques et Micronutriments, INRA Theix, 63122 Saint Genes Champanelle, France
    Br J Nutr 97:1012-20. 2007
  9. ncbi Mortality among workers at a talc mining and milling facility
    Yasushi Honda
    Environmental Health Sciences Program, Institute of Health and Sport Sciences, University of Tsukuba, Japan
    Ann Occup Hyg 46:575-85. 2002
  10. ncbi Presence of talc in pelvic lymph nodes of a woman with ovarian cancer and long-term genital exposure to cosmetic talc
    Daniel W Cramer
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 110:498-501. 2007

Detail Information

Publications256 found, 100 shown here

  1. ncbi Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion
    Carolyn M Dresler
    Head, Tobacco Unit, International Agency for Research on Cancer, Lyon, France
    Chest 127:909-15. 2005
    To demonstrate the efficacy, safety, and appropriate mode of instillation of talc for sclerosis in treatment of malignant pleural effusions (MPEs).
  2. ncbi Iodopovidone: an inexpensive and effective agent for chemical pleurodesis
    Ritesh Agarwal
    Lung Cancer 55:253-4. 2007
  3. ncbi Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: the TIME2 randomized controlled trial
    Helen E Davies
    Department of Respiratory Medicine, University Hospital of Wales, Cardiff, Wales
    JAMA 307:2383-9. 2012
    ..Malignant pleural effusion causes disabling dyspnea in patients with a short life expectancy. Palliation is achieved by fluid drainage, but the most effective first-line method has not been determined...
  4. ncbi Carcinogenicity of carbon black, titanium dioxide, and talc
    Robertv Baan
    Lancet Oncol 7:295-6. 2006
  5. ncbi Inflammatory parameters after pleurodesis in recurrent malignant pleural effusions and their predictive value
    Valiant Ukale
    Department of Medicine, Thoracic Clinics, Karolinska sjukhuset, Stockholm S 171 76, Sweden
    Respir Med 98:1166-72. 2004
    ..Eighty-nine prospective patients with malignant pleural effusion who underwent pleurodesis with either talc (48 patients) or quinacrine (41 patients) were included in the study...
  6. ncbi Pleural mesothelial cells mediate inflammatory and profibrotic responses in talc-induced pleurodesis
    Milena Marques P Acencio
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Lung 185:343-8. 2007
    Intrapleural talc is used to produce pleurodesis in malignant pleural effusions...
  7. ncbi Prospective randomized trial of silver nitrate vs talc slurry in pleurodesis for symptomatic malignant pleural effusions
    Marcello da Silveira Paschoalini
    Perola Byington Hospital, Sao Paulo, Brazil
    Chest 128:684-9. 2005
    To compare the efficacy and the safety of talc slurry and silver nitrate (SN) in the treatment of symptomatic malignant pleural effusions.
  8. ncbi Black Lucques olives prevented bone loss caused by ovariectomy and talc granulomatosis in rats
    Caroline Puel
    Unité des Maladies Métaboliques et Micronutriments, INRA Theix, 63122 Saint Genes Champanelle, France
    Br J Nutr 97:1012-20. 2007
    ..variety prevented bone loss in the whole femur and at cortical sites in those oestrogen-deficient animals with talc inflammation (diaphyseal bone mineral density: black olives and inflammation 0-2323 (SE 0.0026) v...
  9. ncbi Mortality among workers at a talc mining and milling facility
    Yasushi Honda
    Environmental Health Sciences Program, Institute of Health and Sport Sciences, University of Tsukuba, Japan
    Ann Occup Hyg 46:575-85. 2002
    This study evaluated mortality among workers at a talc mining and milling facility.
  10. ncbi Presence of talc in pelvic lymph nodes of a woman with ovarian cancer and long-term genital exposure to cosmetic talc
    Daniel W Cramer
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 110:498-501. 2007
    Although epidemiologic studies suggest talc use may increase ovarian cancer risk, there is no proof that talc used externally reaches the pelvis.
  11. ncbi Thermoplastic starch films reinforced with talc nanoparticles
    Luciana Castillo
    Planta Piloto de Ingeniería Química, PLAPIQUI UNS CONICET, Departamento de Ingenieria Quimica, UNS, Camino La Carrindanga Km 7, 8000 Bahia Blanca, Argentina
    Carbohydr Polym 95:664-74. 2013
    Nanocomposite films of thermoplastic corn starch (TPS) with talc particles were obtained by thermo-compression in order to study the effect of filler on structure, optical, and thermal properties...
  12. ncbi Lung injury following thoracoscopic talc insufflation: experience of a single North American center
    Anne V Gonzalez
    Montreal Chest Institute, McGill University Health Centre, 3650 Saint Urbain St K1 09, Montreal, QC, Canada H2X 2P4
    Chest 137:1375-81. 2010
    Thoracoscopic talc insufflation (TTI) has been used to obliterate the pleural space and prevent recurrent pleural effusions or pneumothorax. Reports of acute pneumonitis and ARDS after the use of talc raised concern about its safety...
  13. ncbi Experimental pleurodesis in rabbits induced by silver nitrate or talc: 1-year follow-up
    F S Vargas
    Laboratory of Pleura, Division of Respiratory Diseases, Heart Institute, InCor, , Brazil
    Chest 119:1516-20. 2001
    STUDY OBJECTIVE: To compare the pleurodesis results from the intrapleural injection of silver nitrate and talc slurry over an observation period of 12 months in rabbits. DESIGN: Rabbits were randomized to receive 2 mL of 0...
  14. ncbi Inflammation and clinical repercussions of pleurodesis induced by intrapleural talc administration
    Eduardo Henrique Genofre
    Laboratory of Pleura, Pulmonary Division Heart Institute Incor University of São Paulo Medical School, Brazil
    Clinics (Sao Paulo) 62:627-34. 2007
    ..Several agents have been studied and used, but talc continues to be the most popular...
  15. ncbi Bedside talc pleurodesis for malignant pleural effusion: factors affecting success
    Umit Aydogmus
    Department of Third Thoracic Surgery, Yedikule Teaching Hospital for Chest Diseases and Thoracic Surgery, Istanbul, Turkey
    Ann Surg Oncol 16:745-50. 2009
    To determine the factors affecting the success of bedside talc slurry (TS) used for symptomatic treatment of patients with malignant pleural effusion (MPE).
  16. ncbi Talc powder vs doxycycline in the control of malignant pleural effusion: a prospective, randomized trial
    Jarosław Kuzdzał
    Department of Thoracic Surgery, Specialized Hospital of Pulmonary Medicine, Zakopane, Poland
    Med Sci Monit 9:PI54-9. 2003
    ..The aim of the study was to assess the efficiency of talc powder and doxycycline in pleurodesis in patients with malignant pleural effusion in comparable conditions.
  17. ncbi Increased pleural fluid adenosine deaminase levels in patients with malignant pleural effusions: a potential predictor of talc pleurodesis outcome
    Huseyin Yildirim
    Department of Chest Diseases, Medical Faculty, Osmangazi University, Meselik, 26480, Eskisehir, Turkey
    Lung 185:349-54. 2007
    ..of this study was to investigate the relationship between pleural fluid adenosine deaminase (Pf-ADA) levels and talc pleurodesis outcomes, and to compare Pf-ADA levels to various other biochemical variables with respect to ..
  18. ncbi Malignant mesothelioma incidence among talc miners and millers in New York State
    Murray M Finkelstein
    Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada
    Am J Ind Med 55:863-8. 2012
    There is controversy about the potential for dust from the talc mines and mills of New York State to cause mesothelioma. Honda et al...
  19. ncbi Thoracoscopic talc versus tunneled pleural catheters for palliation of malignant pleural effusions
    Ben M Hunt
    Division of Thoracic Surgery and Interventional Pulmonology, Center for Pleural Diseases, Swedish Cancer Institute, Swedish Medical Center, Seattle, Washington 98104, USA
    Ann Thorac Surg 94:1053-7; discussion 1057-9. 2012
    ..We compared video-assisted thorascopic (VATS) talc insufflation with placement of a tunneled pleural catheter (TPC) to assess which intervention better met these ..
  20. ncbi Pleurodesis in patients with malignant pleural effusions: talc slurry or bleomycin? Results of a prospective randomized trial
    Fábio José Haddad
    Department of Thoracic Surgery, Hospital do Cancer A C Camargo, University of Sao Paulo, Rua Professor Antonio Prudente 211, LIM 62, 01509 900, UNIP, Sao Paulo, Brazil
    World J Surg 28:749-53; discussion 753-4. 2004
    ..study was to evaluate the efficacy, safety, and cost of bedside pleurodesis for malignant pleural effusions using talc slurry (TS) or bleomycin (BL) in a prospective randomized trial, and to determine prognosticators for procedure ..
  21. ncbi Tumor type influences the effectiveness of pleurodesis in malignant effusions
    Silvia Bielsa
    Pleural Diseases Unit, Department of Internal Medicine, University Hospital Arnau de Vilanova, Institut de Recerca Biomedica de Lleida, Avda Alcalde Rovira Roure 80, 25198 Lleida, Spain
    Lung 189:151-5. 2011
    ..This study investigates the impact of tumor type on the efficacy of bedside doxycycline and thoracoscopic talc poudrage pleurodesis in order to determine which patients may benefit most from these procedures...
  22. ncbi Can serum inflammatory parameters estimate outcome of pleurodesis in mesothelioma?
    Mehmet Bilgin
    Department of Thoracic Surgery, Erciyes University Medical Faculty, Kayseri, Turkey
    ANZ J Surg 77:253-5. 2007
    ..This study was aimed to investigate whether systemic inflammatory reaction induced by insuflation of talc into the pleura can predict the outcome of pleurodesis.
  23. ncbi Application of subcutaneous talc in hernia repair and wide subcutaneous dissection dramatically reduces seroma formation and postoperative wound complications
    David A Klima
    Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Charlotte, North Carolina, USA
    Am Surg 77:888-94. 2011
    ..We evaluate a novel technique of applying talc to wound subcutaneous tissues to decrease wound complications...
  24. ncbi Ultrastructural acute features of active remodeling after chemical pleurodesis induced by silver nitrate or talc
    Eduardo H Genofre
    Laboratory of Pleura, Pulmonary Division, Heart Institute InCor, University of the São Paulo Medical School, Sao Paulo, Brazil
    Lung 183:197-207. 2005
    ..Twenty seven rabbits received intrapleural injection of 0.5% silver nitrate (SN; N = 9) or 400 mg/kg talc slurry (N = 9) in 2 ml of saline solution; control rabbits (N = 9) received 2 ml of saline alone...
  25. pmc Agglomeration of Ibuprofen with talc by novel crystallo-co-agglomeration technique
    Atmaram Pawar
    Department of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Erandwane, Pune 411038, Maharashtra State, India
    AAPS PharmSciTech 5:e55. 2004
    The purpose of this research work was to obtain directly compressible agglomerates of ibuprofen with talc by a novel crystallo-co-agglomeration (CCA) technique, which is an extension of spherical crystallization...
  26. ncbi Design and evaluation of deformable talc agglomerates prepared by crystallo-co-agglomeration technique for generating heterogeneous matrix
    Namdeo Jadhav
    Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur 416013, Maharashtra State, India
    AAPS PharmSciTech 8:E59. 2007
    The crystallo-co-agglomeration technique was used to design directly compressible and deformable agglomerates of talc containing the low-dose drug bromhexine hydrochloride (BXH)...
  27. pmc Comparison of side effects of oxytetracycline and talc pleurodesis: an experimental study
    Alper Gozubuyuk
    Department of Thoracic Surgery, Kirikkale University, School of Medicine, Kirikkale, Turkey
    J Cardiothorac Surg 5:128. 2010
    ..Although several agents have been used, many questions have remained unanswered about their toxicity. Talc is the most commonly used agent for the treatment, with rare, serious complications reported...
  28. ncbi Talc pleurodesis mimics pleural metastases: differentiation with positron emission tomography/computed tomography
    Nirit Weiss
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Clin Nucl Med 28:811-4. 2003
    b>Talc pleurodesis is a technique used in the treatment of patients with persistent pleural effusions or pneumothorax not amenable to other treatment. These are commonly seen in patients with malignant thoracic neoplasms...
  29. ncbi Comparison of pleurodesis by erythromycin, talc, doxycycline, and diazepam in a rabbit model
    Quintessa Miller
    Department of Surgery, Wright State University School of Medicine, Dayton, OH 45409, USA
    J Surg Educ 64:41-5. 2007
    ..b>Talc is the most frequently used chemical sclerosant; however, it has been known to induce Adult Respiratory Distress ..
  30. ncbi Long-term follow-up of thoracoscopic talc pleurodesis for primary spontaneous pneumothorax
    S Györik
    Dept of Pulmonary Medicine, University Hospital Basel, Petersgraben 4, CH 4031, Basel, Switzerland
    Eur Respir J 29:757-60. 2007
    ..present study was to evaluate the long-term outcome of patients with primary spontaneous pneumothorax treated with talc pleurodesis...
  31. ncbi Application of subcutaneous talc after axillary dissection in a porcine model safely reduces drain duration and prevents seromas
    David A Klima
    Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC 28204, USA
    J Am Coll Surg 214:338-47. 2012
    b>Talc, the most common pleurodesis agent, has recently been shown to prevent seromas and decrease drain duration when placed subcutaneously after large subcutaneous dissection accompanying open ventral hernia repair...
  32. ncbi [Case report of a rare occupational disease: a during life non-recognised occupational disease--talcosis]
    V Neumann
    Deutsches Mesotheliomregister am Institut für Pathologie der Ruhr Universität Bochum, Bochum, Germany
    Pneumologie 65:471-6. 2011
    b>Talc is a hydrated magnesium silicate used in the chemical, ceramic, cosmetic, leather, paper and building industries. Interstitial lung disease - talcosis - due to exclusive talc inhalation is a rare form of pneumoconiosis...
  33. ncbi Talc sclerodhesis of persistent Morel-Lavallée lesions (posttraumatic pseudocysts): case report of 4 patients
    Shai Luria
    Department of Orthopedic Surgery, The Hadassah Hebrew University Medical School, Jerusalem 91120, Israel
    J Orthop Trauma 20:435-8. 2006
    ..The standard practice has been repeated extensive surgical debridement. To avoid the need for such treatment, talc was used to sclerose the lesion in 4 patients treated between 2000 and 2003...
  34. ncbi Respiratory effects from industrial talc exposure among former mining workers
    Rosinelle Castelo Branco Ramos Loyola
    Hospital das Clinicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    Rev Saude Publica 44:541-7. 2010
    To evaluate late respiratory effects from occupational inhalation of talc contaminated with asbestos.
  35. ncbi CT with histopathologic correlation of FDG uptake in a patient with pulmonary granuloma and pleural plaque caused by remote talc pleurodesis
    Minh Nguyen
    Department of Radiology, Division of Nuclear Medicine, Atlanta VAMC, 1670 Clairmont Rd, Decatur, GA 30033, USA
    AJR Am J Roentgenol 182:92-4. 2004
  36. ncbi Pulmonary talcosis: imaging findings
    Edson Marchiori
    Department of Radiology, Fluminense Federal University, Rua Thomaz Cameron, 438, Valparaiso, Petropolis, RJ, CEP 25685 120, Brazil
    Lung 188:165-71. 2010
    b>Talc is a mineral widely used in the ceramic, paper, plastics, rubber, paint, and cosmetic industries. Four distinct forms of pulmonary disease caused by talc have been defined...
  37. ncbi A study of comparison of efficacy and safety of talc and povidone iodine for pleurodesis of malignant pleural effusions
    Sibes Kumar Das
    Department of Respiratory Medicine, Calcutta National Medical College and Hospital, Kolkata 700014
    J Indian Med Assoc 106:589-90, 592. 2008
    ..The present study is to compare the effectiveness and safety of talc and povidone iodine as chemical agents for pleurodesis in patients of malignant pleural effusion...
  38. ncbi CT appearances of talc pleurodesis
    S Narayanaswamy
    Department of Radiology, Derriford Hospital, Plymouth, UK
    Clin Radiol 62:233-7. 2007
    To report the computed tomography (CT) appearances of talc pleurodesis in the management of patients with pleural effusions and spontaneous pneumothorax.
  39. ncbi Is talc pleurodesis safe for young patients following primary spontaneous pneumothorax?
    Ian Hunt
    Department of Thoracic Surgery, Guy s Hospital, St Thomas Street, London, UK
    Interact Cardiovasc Thorac Surg 6:117-20. 2007
    ..The question addressed was whether talc used for pleurodesis in young patients with a spontaneous pneumothorax has any long-term adverse effects...
  40. ncbi Perineal application of cosmetic talc and risk of invasive epithelial ovarian cancer: a meta-analysis of 11,933 subjects from sixteen observational studies
    Michael Huncharek
    Department of Clinical Oncology, Marshfield Clinic Cancer Center, Marshfield, WI, USA
    Anticancer Res 23:1955-60. 2003
    Prior epidemiological studies suggest an association between perineal cosmetic talc use and increased risk of epithelial ovarian cancer. A meta-analysis was performed to evaluate this suspected association.
  41. ncbi The primary role of iron-mediated lipid peroxidation in the differential cytotoxicity caused by two varieties of talc nanoparticles on A549 cells and lipid peroxidation inhibitory effect exerted by ascorbic acid
    Mohd Javed Akhtar
    Fibre Toxicology Division, Indian Institute of Toxicology Research CSIR, Lucknow 226 001, UP, India
    Toxicol In Vitro 24:1139-47. 2010
    b>Talc particles, the basic ingredient in different kinds of talc-based cosmetic and pharmaceutical products, pose a health risk to pulmonary and ovarian systems due to domestic and occupational exposures...
  42. ncbi Mechanisms of pleurodesis
    Francisco Rodriguez-Panadero
    Unidad Médico Quirúrgica de Enfermedades Respiratorias, Hospital Universitario Virgen del Rocio, Instituto de Biomedicina de Sevilla, and CIBER Enfermedades Respiratorias, Sevilla, Spain
    Respiration 83:91-8. 2012
    ..There is general agreement that talc obtains the best results, and there are also preliminary experimental studies suggesting that it can induce ..
  43. ncbi Clinical outcomes and health-related quality of life after thoracoscopic talc pleurodesis
    Bodo Schniewind
    Department of General and Thoracic Surgery, University Hospital Schleswig Holstein, Kiel, Germany
    J Palliat Med 15:37-42. 2012
    ..Health-related quality of life (QOL) is an important factor in palliative therapy; however, we are not aware of any studies that have examined the QOL of patients following thoracoscopic pleurodesis...
  44. ncbi An epidemiological study of talc-related respiratory morbidity among employees of a rubber industry in Shiraz-Iran
    M Neghab
    Occupational Health Department, School of Health, Shiraz University of Medical Science, Shiraz, Iran
    Int Arch Occup Environ Health 80:539-46. 2007
    The main purpose of this study was to assess and characterize the pulmonary reactions associated with occupational exposure to talc dust.
  45. ncbi Single versus multiple access video-assisted thoracic surgery in the treatment of malignant pleural effusion
    Stefano Margaritora
    Eur J Cardiothorac Surg 32:397; author reply 397-8. 2007
  46. ncbi Carcinogenic hazards from inhaled carbon black, titanium dioxide, and talc not containing asbestos or asbestiform fibers: recent evaluations by an IARC Monographs Working Group
    Robert A Baan
    Carcinogen Identification and Evaluation Group, WHO International Agency for Research on Cancer, Lyon, France
    Inhal Toxicol 19:213-28. 2007
    ..IARC Monographs Working Group reevaluated the carcinogenic hazards to humans of carbon black, titanium dioxide, and talc, which belong to the group of poorly soluble, low-toxicity particles...
  47. ncbi Alternative widely available, inexpensive agents for pleurodesis
    Oner Dikensoy
    Department of Pulmonary Diseases, School of Medicine, Gaziantep University, Turkey
    Curr Opin Pulm Med 11:340-4. 2005
    ..Although talc, parenteral tetracycline derivatives, and bleomycin are the most commonly used agents for pleurodesis, parenteral ..
  48. ncbi Transforming growth factor beta induces vascular endothelial growth factor elaboration from pleural mesothelial cells in vivo and in vitro
    Y C Gary Lee
    Department of Pulmonary Medicine, St Thomas Hospital and Vanderbilt University, Nashville, Tennessee 37202, USA
    Am J Respir Crit Care Med 165:88-94. 2002
    ..growth factor beta (TGF-beta) to produce pleurodesis, we observed that although TGF-beta was more effective than talc or doxycycline, it induced transient production of large pleural effusions...
  49. ncbi Efficacy of video-assisted thoracoscopic surgery with talc pleurodesis for porous diaphragm syndrome in patients with refractory hepatic hydrothorax
    Robert J Cerfolio
    Division of Cardio Thoracic Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Ann Thorac Surg 82:457-9. 2006
    ..Patients with recurrent, refractory hepatic hydrothorax from porous diaphragm syndrome represent a therapeutic challenge with few options...
  50. ncbi Talc and silver nitrate induce systemic inflammatory effects during the acute phase of experimental pleurodesis in rabbits
    Evaldo Marchi
    Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Chest 125:2268-77. 2004
    s: To determine whether talc (TL) and silver nitrate (SN), two effective pleurodesis agents, induce a systemic inflammatory response in the acute phase of experimental pleurodesis in rabbits.
  51. ncbi Talc seromadesis: a novel technique for the treatment of chronic seromas following breast surgery
    Kourosh Saeb-Parsy
    Breast J 12:502-4. 2006
  52. ncbi Pleurodesis practice for malignant pleural effusions in five English-speaking countries: survey of pulmonologists
    Y C Gary Lee
    University of Oxford and Osler Chest Unit, Churchill Hospital, Oxford OX3 7BN, UK
    Chest 124:2229-38. 2003
    ..Pleurodesis is important in the management of malignant pleural effusions, but no consensus exists on the optimal agent or methods of pleurodesis. How pleurodesis is practiced worldwide has not been studied...
  53. ncbi Talc pleurodesis: basic fibroblast growth factor mediates pleural fibrosis
    Veena B Antony
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Florida, PO Box 100225, Gainesville, FL 32610 0225, USA
    Chest 126:1522-8. 2004
    ..Pleurodesis involves the introduction of a sclerosing agent into the pleural space. Talc is one of the most commonly used sclerosing agents in treating patients with recurrent, symptomatic malignant ..
  54. ncbi Is full postpleurodesis lung expansion a determinant of a successful outcome after talc pleurodesis?
    Ricardo Mingarini Terra
    Division of Thoracic Surgery, Heart Institute InCor, Hospital das Clinicas, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Chest 136:361-8. 2009
    To analyze and compare radiologic lung expansion after talc pleurodesis performed either by videothoracoscopy or chest tube and correlate it with clinical outcome...
  55. ncbi Who gains most? A 10-year experience with 611 thoracoscopic talc pleurodeses
    Volker Steger
    Department of Thoracic Surgery, Schillerhoehe Hospital, Gerlingen, Germany
    Ann Thorac Surg 83:1940-5. 2007
    Thoracoscopic talc pleurodesis is a therapeutic option for recurrent pleural effusion.
  56. ncbi Evidence that mesothelial cells regulate the acute inflammatory response in talc pleurodesis
    E Marchi
    Pleura Laboratory Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Eur Respir J 28:929-32. 2006
    Intrapleural instillation of talc is used to produce pleurodesis in cases of recurrent malignant pleural effusions...
  57. ncbi Talc mediates angiostasis in malignant pleural effusions via endostatin induction
    N Nasreen
    Division of Pulmonary and Critical Care Medicine, Dept of Medicine, University of Florida, Gainesville, FL, USA
    Eur Respir J 29:761-9. 2007
    b>Talc remains the most effective sclerosing agent for pleurodesis. However, its mechanism of action in resolving pleural malignant disease remains unclear...
  58. ncbi Interleukin-8 activates coagulation and correlates with survival after talc pleurodesis
    A Montes-Worboys
    Institute of Biomedicine of Seville IBIS, HHUU Virgendel Rocío, Seville, Spain
    Eur Respir J 35:160-6. 2010
    The aim of our study was to investigate whether interleukin (IL)-8 activates systemic coagulation after talc pleurodesis in malignant pleural effusion (MPE), and whether levels of IL-8 in plasma are related to early death after talc ..
  59. ncbi Randomized trials describing lung inflammation after pleurodesis with talc of varying particle size
    Nick A Maskell
    Oxford Pleural Disease Clinic, Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford Radcliffe NHS Trust, Oxford OX3 7LJ, UK
    Am J Respir Crit Care Med 170:377-82. 2004
    We report two trials describing whether talc pleurodesis with a mean particle size of less than 15 microm ("mixed" talc) produces more lung and systemic inflammation than tetracycline or "graded" talc (most particles < 10 microm were ..
  60. ncbi F-18 FDG PET/CT characterization of talc pleurodesis-induced pleural changes over time: a retrospective study
    Nghi C Nguyen
    Division of Nuclear Medicine, Department of Radiology, School of Medicine, St Louis University, St Louis, MO 63110, USA
    Clin Nucl Med 34:886-90. 2009
    The current study characterized pleural changes induced by talc pleurodesis (TP), based on serial positron emission tomography/computer-tomography (PET/CT) with F-18 fluorodeoxyglucose (FDG).
  61. pmc Synthesis and characterization of silver/talc nanocomposites using the wet chemical reduction method
    Kamyar Shameli
    Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia
    Int J Nanomedicine 5:743-51. 2010
    ..nanoparticles (Ag-NPs) were synthesized using the wet chemical reduction method on the external surface layer of talc mineral as a solid support...
  62. ncbi An Audit of medical thoracoscopy and talc poudrage for pneumothorax prevention in advanced COPD
    Pyng Lee
    Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore
    Chest 125:1315-20. 2004
    To prospectively study all patients with COPD and spontaneous pneumothorax (SP) who underwent thoracoscopic talc poudrage (TP) under local anesthesia to determine its efficacy and safety in recurrence prevention.
  63. ncbi Thoracoscopy and talc poudrage in the management of hepatic hydrothorax
    J R Milanez de Campos
    Division of Thoracic Surgery, Hospital Israelita Albert Einstein and Hospital das Clínicas of the University of São Paulo Medical School, Sao Paulo, Brazil
    Chest 118:13-7. 2000
    ..To determine indications, limitations, morbidity and mortality of surgical thoracoscopy for management of hepatic hydrothorax, a rare, but often recurrent, complication in cirrhotic patients...
  64. ncbi Thoracoscopy talc poudrage : a 15-year experience
    J R de Campos
    Division of Thoracic Surgery, University of San Paulo, Medical School, San Paulo, Brazil
    Chest 119:801-6. 2001
    To review our experience with thoracoscopy and talc poudrage during the previous 15 years with regards to efficacy, side effects, morbidity, and mortality.
  65. ncbi Talc preparations used for pleurodesis vary markedly from one preparation to another
    J Ferrer
    Servei de Pneumologia, Hospital Vall d'Hebron, Barcelona, Spain
    Chest 119:1901-5. 2001
    BACKGROUND: At the present time, talc is the one of the agents most commonly used for the production of a pleurodesis...
  66. pmc Treatment of malignant pleural effusion: PleuRx catheter or talc pleurodesis? A cost-effectiveness analysis
    Aaron M Olden
    Division of Ethics, Humanities, and Palliative Care, University of Rochester, Rochester, New York 14642, USA
    J Palliat Med 13:59-65. 2010
    ..may be quick and relatively easy to perform, but has a high recurrence rate; chest tube placement with talc slurry is quite effective at achieving pleurodesis, but this procedure can be quite painful and requires ..
  67. ncbi Use of tunnelled catheters for malignant pleural effusions in patients fit for pleurodesis
    A Tremblay
    Division of Respiratory Medicine, Health Sciences Center, Calgary, AB, Canada
    Eur Respir J 30:759-62. 2007
    ..Tunnelled pleural catheters are an effective way of controlling malignant pleural effusions when used as first-line treatment in patients who appear to be candidates for pleurodesis procedures...
  68. pmc Early and late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions: a review of 400 cases
    Nikolaos Barbetakis
    Thoracic Surgery Department, Theagenio Cancer Hospital, A, Simeonidi 2, Thessaloniki, 54007, Greece
    J Cardiothorac Surg 5:27. 2010
    ..It represents a terminal condition with short median survival (in terms of months) and the goal is palliation. Aim of our study is to analyze morbidity, mortality and life expectancy following videothoracoscopic talc poudrage.
  69. ncbi A randomized controlled trial of the efficacy of cosmetic talc compared with iodopovidone for chemical pleurodesis
    Ritesh Agarwal
    Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Respirology 16:1064-9. 2011
    b>Talc is an effective and widely used agent for chemical pleurodesis. However, limited availability and high cost hamper the routine use of talc in resource poor countries...
  70. ncbi Perineal use of talc and risk of ovarian cancer
    H Langseth
    The Cancer Registry of Norway, Institute of populationbased, Cancer Research, Oslo, Norway
    J Epidemiol Community Health 62:358-60. 2008
    ..Some environmental exposures, notably talc and asbestos, have been suspected as ovarian carcinogens.
  71. ncbi Video-assisted thoracoscopic surgery with talc pleurodesis in the management of symptomatic hepatic hydrothorax
    Dino Ferrante
    Division of Gastroenterology and Hepatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 005, USA
    Am J Gastroenterol 97:3172-5. 2002
    Video-assisted thoracoscopic surgery with talc pleurodesis is a therapeutic option for patients with hepatic hydrothorax that is refractory to medical therapy...
  72. ncbi Talc poudrage versus talc slurry in the treatment of malignant pleural effusion. A prospective comparative study
    Alessandro Stefani
    Division of Thoracic Surgery, Department of General Surgery and Surgical Specialities, University of Modena and Reggio Emilia, Italy
    Eur J Cardiothorac Surg 30:827-32. 2006
    The aim of this study was to investigate the effectiveness, safety and appropriate mode of administration of intrapleural talc for pleurodesis, in the treatment of malignant pleural effusion (MPE).
  73. ncbi The evidence on the effectiveness of management for malignant pleural effusion: a systematic review
    Carol Tan
    Thoracic Unit, Guy s Hospital, St Thomas Street, London SE1 9RT, United Kingdom
    Eur J Cardiothorac Surg 29:829-38. 2006
    ..b>Talc tended to be associated with fewer recurrences when compared to bleomycin (RR, 0.64; 95% CI, 0.34-1...
  74. ncbi Pleurodesis for malignant pleural effusion: talc, toxicity and where next?
    Helen E Davies
    Thorax 63:572-4. 2008
  75. ncbi Risk of lung cancer following exposure to carbon black, titanium dioxide and talc: results from two case-control studies in Montreal
    Agnihotram V Ramanakumar
    Centre de Recherche du CHUM, Universite de Montreal, Montreal, Quebec, Canada
    Int J Cancer 122:183-9. 2008
    ..evaluated the carcinogenicity of three poorly soluble weakly-toxic substances: carbon black, titanium dioxide and talc. Though there is evidence of carcinogenity in experimental animals for these substances, the evidence in humans is ..
  76. doi Talc retinopathy
    Vinay A Shah
    Ophthalmology 115:755-755.e2. 2008
  77. ncbi False positive 18F-FDG-PET/CT in a patient after talc pleurodesis
    Hojjat Ahmadzadehfar
    Department of Nuclear Medicine, University Hospital Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany
    Lung Cancer 58:418-21. 2007
    ..After diagnosis of emphysemic bullae, the patient underwent talc pleurodesis and had no further complaints...
  78. ncbi Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study
    Julius P Janssen
    Canisius Wilhelmina Hospital, Nijmegen, Netherlands
    Lancet 369:1535-9. 2007
    b>Talc is the most effective chemical pleurodesis agent for patients with malignant pleural effusion...
  79. ncbi Some reflections on talc poudrage
    Thomas F Molnar
    Eur J Cardiothorac Surg 31:1147; author reply 1147-8. 2007
  80. ncbi Clinical efficacy and safety of thoracoscopic talc pleurodesis in malignant pleural effusions
    Steffen Kolschmann
    St George Medical Center, Robert Koch Hospital, Nikolai Rumjanzew Str 100, D 04207 Leipzig, Germany
    Chest 128:1431-5. 2005
    ..The purpose of this study was to determine the long-term efficacy and safety of pleurodesis by thoracoscopic talc poudrage (TTP) in malignant pleural effusions (MPEs).
  81. ncbi Who's (still) afraid of talc?
    M Noppen
    Eur Respir J 29:619-21. 2007
  82. ncbi Foreign body post-varicella granulomas due to talc
    C Lazaro
    Department of Dermatology, Lozano Blesa University Hospital, Zaragoza, Spain
    J Eur Acad Dermatol Venereol 20:75-8. 2006
    ..with multiple facial granulomas, persisting more than 6 months and related to the use of topical anti-pruriginous talc powder applied to papuloexudative lesions caused by varicella...
  83. ncbi Videothoracoscopic talc poudrage in primary spontaneous pneumothorax: a single-institution experience in 861 cases
    Giuseppe Cardillo
    Thoracic Surgery Unit, Carlo Forlanini Hospital, Azienda Ospedaliera San Camillo Forlanini, Medicine University of Rome La Sapienza, Rome, Italy
    J Thorac Cardiovasc Surg 131:322-8. 2006
    We sought to evaluate the outcome of 861 patients treated with videothoracoscopic talc poudrage for primary spontaneous pneumothorax.
  84. ncbi The neutrophilic and fibrinolytic response to talc can predict the outcome of pleurodesis
    K Psathakis
    Department of Pneumonology, Army General Hospital of Athens, Athens, Greece, and Respiratory Endoscopy Unit, Unidad Médico Quirúrgica de Enfermedades Respiratorias, Hospital Universiatrio Viergen del Rocío, Sevilla, Spain
    Eur Respir J 27:817-21. 2006
    It was hypothesised that monitoring neutrophil and D-dimer (DD) levels into the pleural fluid, after talc instillation, could predict the outcome of pleurodesis...
  85. ncbi Long-term follow-up of video-assisted talc pleurodesis in malignant recurrent pleural effusions
    G Cardillo
    Department of Thoracic Surgery, Carlo Forlanini Hospital, Via Portuense 332, 00149, Rome, Italy
    Eur J Cardiothorac Surg 21:302-5; discussion 305-6. 2002
    ..Recurrent pleural effusion is a common condition and often presents a challenge for treatment. The aim of this report is to evaluate the long-term follow-up of thoracoscopic management of malignant recurrent pleural effusions...
  86. ncbi Pleurodesis induced by talc or silver nitrate: evaluation of collagen and elastic fibers in pleural remodeling
    Leila Antonangelo
    Laboratory of Pleura Pulmonary Division and Division of Applied Physiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Lung 184:105-11. 2006
    This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN)...
  87. ncbi Intrapleural low-dose silver nitrate elicits more pleural inflammation and less systemic inflammation than low-dose talc
    Evaldo Marchi
    Pleura Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Brazil, Rua Lucia B Passarin, 590, Ap 42, Jundiai, Sao Paulo, Brazil
    Chest 128:1798-804. 2005
    Several systemic effects have been described after talc pleurodesis. The aim of this study was to assess the systemic response induced by low, nonpleurodesis-inducing doses of talc and silver nitrate in an experimental model in rabbits.
  88. ncbi An update of a mortality study of talc miners and millers in Italy
    Maurizio Coggiola
    Dipartimento di Traumatologia, Ortopedia e Medicina del Lavoro dell Università di Torino, Turin, Italy
    Am J Ind Med 44:63-9. 2003
    While talc containing asbestiform fibers is considered a human carcinogen, only limited animal and human data are available on non-asbestiform talc...
  89. ncbi Influence of particle size on extrapleural talc dissemination after talc slurry pleurodesis
    Jaume Ferrer
    Servei de Pneumologia, Hospital General Vall d Hebron, Barcelona, Spain
    Chest 122:1018-27. 2002
    Cases of acute respiratory failure reported after talc pleurodesis have raised concerns about its safety. It has been speculated that this pulmonary inflammatory syndrome is secondary to the extrapleural dissemination of the talc particles...
  90. ncbi Talc for pleurodesis?
    Richard W Light
    Chest 122:1506-8. 2002
  91. ncbi Inhalational pulmonary talcosis: high-resolution CT findings in 3 patients
    Edson Marchiori
    Departmento de Radiologia, Hospital Universitario Clementino Fraga Filho, RJ, Rio de Janeiro, Brazil
    J Thorac Imaging 19:41-4. 2004
    We describe the high-resolution CT findings in 3 patients with pulmonary talcosis acquired by the inhalation of talc. The predominant abnormalities consisted of small centrilobular and subpleural nodules and conglomerated masses ..
  92. ncbi Distribution of calibrated talc after intrapleural administration: an experimental study in rats
    Anne Fraticelli
    Department of Pulmonary Diseases, Hopital Sainte Marguerite, Marseille, France
    Chest 122:1737-41. 2002
    Many reports have shown that talc is the most effective and least expensive agent for the creation of a pleural symphysis...
  93. pmc A cohort mortality and nested case-control study of French and Austrian talc workers
    P Wild
    Institut National de Recherche et de Securite, Département Epidémiologie, Vandoeuvre, France
    Occup Environ Med 59:98-105. 2002
    To study whether the mortality from non-malignant and malignant respiratory diseases of workers employed in French and Austrian talc mines and mills is related to their long term occupational exposure.
  94. ncbi Serious complications with talc slurry pleurodesis
    A Brant
    Department of Respiratory Medicine, Green Lane Hospital, Auckland, New Zealand
    Respirology 6:181-5. 2001
    OBJECTIVE: Talc is a highly efficacious and commonly employed agent for chemical pleurodesis, which has generally been felt to be well tolerated...
  95. ncbi Early and late mortality after pleurodesis for malignant pleural effusion
    Alain Bernard
    Chirurgie Thoracique, Hopital Universitaire, Dijon, France
    Ann Thorac Surg 74:213-7. 2002
    ....
  96. ncbi Fluorodeoxyglucose positron emission tomography and CT after talc pleurodesis
    Boon Han Kwek
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA
    Chest 125:2356-60. 2004
    b>Talc pleurodesis is widely performed for the management of persistent pneumothorax or pleural effusion, particularly malignant effusions...
  97. ncbi Lung damage in experimental pleurodesis induced by silver nitrate or talc: 1-year follow-up
    Francisco S Vargas
    Pleura Laboratory, Division of Respiratory Diseases, University of Sao Paulo Medical School, R Itapeva 500 cjto 4C, Bela Vista, Sao Paulo, Brazil CEP 01332 000
    Chest 122:2122-6. 2002
    To compare the lung damage caused by intrapleural silver nitrate (SN) with that caused by talc over a 12-month period.
  98. ncbi Systemic distribution of talc after intrapleural administration in rats
    E C Werebe
    Department of Cardiology and Pulmonary Medicine, Faculty of Medicine, University of Sao Paulo, Brazil
    Chest 115:190-3. 1999
    Many reports have shown the efficacy of talc to induce an effective pleurodesis. However, there is little information about the side effects related to this sclerosing agent...
  99. ncbi Influence of talc dose on extrapleural talc dissemination after talc pleurodesis
    Juan F Montes
    Departament deBiologia Cel lular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Am J Respir Crit Care Med 168:348-55. 2003
    This study was designed to ascertain, in a rabbit model, extrapleural talc deposition and the related inflammatory response after talc slurry pleurodesis with two clinical doses, 200 and 50 mg/kg...
  100. ncbi A comparative study of pleurodesis using talc slurry and bleomycin in the management of malignant pleural effusions
    K C Ong
    Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore
    Respirology 5:99-103. 2000
    ..A randomized clinical trial was conducted to compare the efficacy of two commonly used agents, talc and bleomycin, for the pleurodesis of malignant pleural effusions.
  101. ncbi Video-assisted thoracoscopic talc pleurodesis is effective for maintenance of peritoneal dialysis in acute hydrothorax complicating peritoneal dialysis
    Sydney Tang
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, Peoples Republic of China
    Nephrol Dial Transplant 18:804-8. 2003
    ..Its clinical course and treatment outcome after a recently advocated technique of video-assisted thoracoscopic (VATS) talc pleurodesis remains unclear.

Research Grants16

  1. Identifying Ovarian Cancer Susceptibility Alleles using Genome-Wide Scan Data
    Celeste Leigh Pearce; Fiscal Year: 2012
    ..factors associated with ovarian cancer have been identified, including menopausal hormone therapy use, perineal talc use, obesity, infertility, parity, breast-feeding, oral contraceptive use, and tubal ligation, In this proposal we ..
  2. Dana-Farber/Harvard Cancer Center Ovarian Cancer SPORE
    DANIEL WILLIAM CRAMER; Fiscal Year: 2010
    ..examine gene-environmental interactions affecting modifiable exposures, such as anti-inflammatory drug or genital talc use, in combined data from the Nurses'Health Cohort and a large case-control study...
  3. Characteristics of tubal ligation and risk of epithelial ovarian cancer
    Shelley S Tworoger; Fiscal Year: 2012
    ..g., oral contraceptive use, genital talc use, and individual risk of ovarian cancer) as well as tumor characteristics...
  4. TGF-BETA FOR PLEURODESIS
    Kirk Lane; Fiscal Year: 2000
    ..The FDA currently approves one compound in each category, talc or bleomycin respectively, for pleurodesis...
  5. TGF-BETA FOR PLEURODESIS
    Kirk Lane; Fiscal Year: 2005
    ..Abrasion requires hospitalization and general anesthesia, the most common irritant used is talc, which has occasional fatal side effects, and the induction of a pleural burn can be extremely painful...
  6. Psychosocial Support to HIV/AIDS Affected Children in Zimbabwe
    Danuta Kasprzyk; Fiscal Year: 2009
    ..data from current research, to adapt and implement a psychosocial support and coping skills intervention (Project TALC/TLC/CLEAR) with adolescent children (12-18) living with an HIV-positive parent;2) to pilot test the intervention in ..
  7. IMPACT OF AIDS ON ADOLESCENTS TRANSITION TO ADULTHOOD
    MARY ROTHERAM BORUS; Fiscal Year: 2002
    ..we have successfully designed, implemented, and assessed the impact of an enhanced intervention program (Project TALC) with Parents with AIDS (PWA), their adolescent children (Youth of PWA), and the new Caregivers in a randomized ..
  8. Enzymatic Pleurodesis for Malignant Pleural Effusions
    Larry Tsai; Fiscal Year: 2005
    ..formulation to maximize safety and effectiveness in vivo, and 2) comparing responses following enzymatic treatment to those following talc slurry, the current standard non-surgical treatment for malignant effusions in clinical practice.
  9. EPIDEMIOLOGIC AND BIOLOGIC PREDICTORS OF IVF SUCCESS
    Daniel Cramer; Fiscal Year: 2002
    ....
  10. MUC-1 related cancer immunity: determinants and predictive significance
    Daniel Cramer; Fiscal Year: 2009
    ..The findings of our study could provide the basis for developing a safe cancer- preventing vaccine for ovarian cancer and perhaps other MUC1-expressing tumors. ..
  11. Risk for New onset of Depression in Perimenopausal Women
    Daniel Cramer; Fiscal Year: 2009
    ..abstract_text> ..
  12. Genes, Hormones & Environment in an Ovarian Cancer Model
    Daniel Cramer; Fiscal Year: 2007
    ..ovarian cancer risk, including Ahr, CYP1A1, COMT, MnSOD, GST, and NAT and may interact with exposures like genital talc. Protection from ovarian cancer is associated with a variety of antioxidants including lycopene, carotene, ginkgo, ..
  13. EVAPORATIVE LOSSES FROM SEMI-VOLATILE MIST SAMPLES
    Peter Raynor; Fiscal Year: 2002
    ..Reevaluated data may be able to be used more effectively in epidemiological studies on the health effects of metalworking fluid mists. ..
  14. Photodynamic Therapy for the Treatment of Obstructive E*
    Todd Demmy; Fiscal Year: 2007
    ..This proposal will be instrumental in the development of a novel PDT drug without long-term restrictions of patients' sun exposure. [unreadable] [unreadable]..
  15. Polybrominated Biphenyls and Cancer Risk
    KARIN ROSENBLATT; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  16. Mammographic Densities: In the Pathway to Breast Cancer?
    KARIN ROSENBLATT; Fiscal Year: 2005
    ..abstract_text> ..