dietary iron

..Duodenal expression levels of Dcytb messenger RNA and protein were regulated by changes in physiological modulators of iron absorption. Thus, Dcytb provides an important element in the iron absorption pathway...

..It is possible that overweight individuals may have lower dietary iron intake and/or bioavailability...

..Duodenal HFE expression was positively associated with serum iron and liver HFE levels. Dietary iron supplementation decreased HFE in the duodenum but not in the liver...

OBJECTIVE: This study developed and validated an iron checklist for assessing dietary iron intake of pregnant and postpartum women. METHODS: The checklist included 65 food and drink items...

..The possibility of differential compliance between the regimens needs to be evaluated to explain these findings...

..Experiments were designed to test the impact of dietary iron availability on the pathogenic process and functional outcome in a mouse model of PD...

..Excessive iron stores may promote insulin resistance and lead to the development of type 2 diabetes. However, prospective data relating iron intake and blood donations (determinants of body iron stores) to diabetes incidence are limited...

..High dietary iron increased liver iron concentrations slightly (P < 0...

..We wanted to explore the association between dietary iron intake and indicators of iron status, and to assess temporal changes in these variables...

..5 wk despite no effect on weight. Although dietary iron restriction preserved beta-cell function in ob/ob mice fed a high-fat diet, the effects on overall glucose ..

..4 (95% CI, 1.2-4.6) compared with children with a single parasite species. Children with an adequate intake of iron had no increased odds of anemia independent of the combination of parasite infections...

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..To evaluate the effect of iron supplementation on physical growth in children through a systematic review of randomised controlled trials (RCTs)...

..This is of specific interest since iron is frequently included in supplementation and fortification of foods. We assessed the relation between dietary iron intake and the risk of non-fatal AMI.

..Current developments in biotechnology-assisted plant improvement are reviewed and the potential of the technology in addressing human nutrition and health are discussed...

..It is a common belief among women that iron compounds have unpleasant gastrointestinal side effects...

There is accumulating evidence that high levels of dietary iron may play a role in colon carcinogenesis...

..The correlation between duodenal DMT1 and MTP1 expression and Cd body burden in rats suggests an important role of DMT1 and MTP1 in Cd absorption...

..8-fold induction) of zebrafish fed a low Fe diet. The correlation between Cd uptake and DMT1 expression suggests that one route of uptake of Cd, either from the diet or from the water, could be via DMT1...

..We carried out a prospective study of dietary iron intake and incidence of Type 2 diabetes...

Iron homeostasis plays a critical role in many physiological processes, notably synthesis of heme proteins. Dietary iron sensing and inflammation converge in the control of iron absorption and retention by regulating the expression of ..

This study investigates anaemia related to the sufficiency of dietary iron intake of school-aged children in the Kzyl-Orda region of Kazakhstan. We conducted a cross-sectional study of 97 school-aged children living in Kzyl-Orda...

..Gene mutations associated with iron overload have been identified. How food and nutrient intakes affect iron status in persons who may be at risk of iron overload because their genetic status is unknown...

..A series of experiments were designed in order to test the hypothesis that host dietary iron restriction mediates susceptibility to hookworm infection using the hamster model of Ancylostoma ceylanicum...

Iron may play an important role in the pathogenesis of hepatitis C. We conducted this randomized, controlled trial comparing phlebotomy with dietary iron reduction.

..Data from a food frequency questionnaire administered at baseline were used to calculate total dietary iron and heme iron intake...

To determine whether increased dietary iron could be a risk factor for active tuberculosis, dietary iron history and human immunodeficiency virus (HIV) status were studied in 98 patients with pulmonary tuberculosis and in 98 control ..

..We speculate that dietary iron deprivation leads to increased intestinal copper absorption via DMT1 on the brush-border membrane and the ..

b>Dietary iron overload occurs commonly in parts of sub-Saharan Africa. It results from the consumption of large volumes of traditional beer that is home-brewed in iron pots or drums and consequently has a high iron content...

To evaluate human immunodeficiency virus (HIV) serology, dietary iron and serum concentrations of markers of T-helper type (Th) 1 and Th-2 immune pathways in the setting of tuberculosis (TB).

..Acute lymphoblastic leukaemia is the most common childhood cancer in more-developed countries but it has few recognised risk factors or preventive measures. We aimed to determine and assess the risk factors associated with this disease...

There is increasing evidence that excess dietary iron may be a risk factor for colorectal cancer. However, the majority of animal studies looking at possible mechanism have used unrealistically high concentrations of iron...

..In summary, effectively combining and balancing the needs of program implementation, research and community involvement will help combat Fe deficiency...

..The likely liability in iron nutriture in free-living, elderly white Americans eating a Western diet is high iron stores, not iron deficiency...

..We investigated changes in intestinal DMT1 expression after a bolus of dietary iron in iron-deficient Belgrade rats homozygous for the DMT1 G185R mutation (b/b) and phenotypically normal ..

..9, 95% CI: 1.2, 2.9). No strong associations were found for either antioxidants or fats. CONCLUSION: A high intake of iron, especially in combination with high manganese intake, may be related to risk for PD...

..We assessed dietary iron intake and genetic and biochemical markers of iron status in a prospective, nested case-control study of women ..

..These findings regarding iron and copper suggest that free radicals play an important role in colorectal carcinogenesis, while the findings regarding vitamin E are so far unexplained...

..The hypertrophy pattern present in iron-deficiency anemia is in contrast to other nutritional models of hypertrophy, such as copper-deficiency, where a concentric hypertrophy occurs both in the presence and absence of anemia...

..001). The present findings have implications for the management of human UC and suggest that dietary iron can enhance UC and its associated carcinogenesis by augmenting oxidative and nitrosative stress.

..Iron status in childhood is influenced by diet. Other factors affecting iron status at that age are unclear...

..Iron utilization may have been impaired by the high prevalence of malaria and concurrent nutrient deficiencies...

..Determination of risk factors associated with ID is needed to allow children with identifiable risk factors to receive appropriate education, testing, and follow-up...

..This review aims to describe factors that may cause anemia in Inuit populations despite high meat intakes, abundant bioavailable iron, and other important hematological nutrients...

..NaFeEDTA-fortified soy sauce is affordable and was well accepted by the study population...

..CONCLUSIONS: Iron fortified follow-on milk, iron fortified partially modified cows' milk, and iron medicine all effectively treat IDA in infancy...

..Current information suggests that in the UK Fe deficiency is a greater problem than Fe overload...

..The lack of direct comparison between single-agent ferrous fumarate and the combination ferrous product limited interpretation of results in terms of possible effects due to other components, such as ascorbic acid...

..For women who are underweight, the administration of iron-fortified milk has additional benefits to those of supplementation, most likely due to additional energy and nutrient inputs...

..Studies in pregnant women are limited in number, have had inconsistent results, and have not accounted for maternal iron supplementation...

..Despite large populations carrying traits for thalassemia in countries implementing universal iron fortification, there are few data on the absorption and utilization of iron in these persons...

..Nonetheless, relatively few efficacy trials have been reported to date to demonstrate impact on iron status. The Ultra Rice technology provides a means of delivering fortificant iron via rice...

..Higher hepcidin levels in obesity may reduce dietary iron absorption...

..Anemia is prevalent in China. Tofu made from soybean is a popular food. Soybean is shown to have an affect on iron status. No study has examined the relation between tofu and iron status...

..We investigated iron intake and iron absorption in the ordinary diet of free-living individuals in relation to iron status and assessed iron requirements...

..56 to 5.94 microg/dl and Hb levels from 7.54 to 8.29 g/dl. Thus, improving the bioavailability of iron of food preparations, will improve the iron status of women...

..Although elemental iron powders are widely used to fortify cereal products, little data exist on their efficacy in humans...

..This study demonstrated the feasibility of incorporating both iron and vitamin B1 in a stable Ultra Rice formulation. Inclusion of other stable B vitamins in the formulation should be also feasible...

..Food iron fortification can be a good strategy to prevent iron deficiency. Iron bioavailability from cocoa powder enriched with ferric pyrophosphate encapsulated in liposomes or ferrous fumarate was assessed in rats...

..Infants aged 6-24 mo are at high risk of iron deficiency. Numerous studies worldwide have sought to identify predictors of iron deficiency in this age group...

..Here, we focus on these intriguing new molecules and the insights gained from them into cellular iron uptake and the regulation of iron metabolism...

..To compare the effects of wheat flours fortified with NaFeEDTA, FeSO4 and elemental iron (electrolytic iron), in improving iron status in anemic students...

..Iron deficiency in children is a major worldwide nutritional problem. An oat beverage was developed for 1- to 3-year-old children and different treatments were used to improve the iron bioavailability...

..This could be due to the relatively short duration of the follow-up period. A longer follow-up period is recommended to detect the effect of the maternal iron supplementation during lactation...

..Children participating in the Integrated Child Development Service (ICDS) in India have high rates of iron and vitamin A deficiency...

..It has also been suggested that iron supplements may have adverse effects in children...

..Anemia and iron deficiency are significant public health problems in India, particularly among women and children. Recent figures suggest that nearly 50% of young Indian women are anemic...

..Single-meal and short-term studies have shown an enhancing effect of meat on iron absorption, but there are few interventions of longer duration comprising measurements of biomarkers of iron status...

..Whether the disjuncture between recommended and actual Fe intakes among infants born with low Fe reserves and weaned to foods low in bioavailable Fe has functional consequences is worthy of further investigation...

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..The combined addition of meat and ascorbic acid to a meal has the potential to reduce the projected prevalence of inadequate iron intakes among these schoolchildren...

..These results show that according to this method, the iron bioavailability from industrial fortified petit suisse cheese can be considered as a high bioavailability rate...

..To identify iron sources for wheat- (WF) and corn-flour (CF) fortification taking into account the effect of cooking...

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..To investigate risk factors for anemia in infants assisted by public health services...

..The current iron-folate supplementation program for pregnant women should be expanded to adolescent girls...

..seekers' children in the Netherlands, biochemical iron status and the prevalence of iron deficiency (ID) and anemia in relation to age, region of origin, length of stay in the Netherlands, body mass index (BMI), and dietary iron intake.

..Overall, for infants, combined iron and zinc supplementation is preferable to iron or zinc supplementation alone...

..Iron and riboflavin affect vitamin A utilization and photoreceptor function, respectively, and pilot data in the study population showed a high prevalence of iron and riboflavin deficiencies...

..In areas of subsistence farming in rural Africa, salt is one of the few regularly purchased food items and could be a good fortification vehicle for iodine and iron, provided that a stable yet bioavailable iron fortificant is used...

..CONCLUSION: There may be significant health benefits from a program that enhances the nutritional status of iron, folate, and vitamin A in poor urban young women before they become pregnant...

..CONCLUSIONS: While iron status is fairly good among Finnish males, especially in younger women it is suboptimal,with iron intake failing to reach recommended levels. Food consumption was poorly associated with iron status...

..The iron intakes of this group of Caucasian infants and young children appeared inadequate. However, their rate of iron deficiency anaemia was lower than has been reported in previous New Zealand studies...

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..It was concluded that nutritional intervention for anaemic students using NaFeEDTA-fortified soy sauce could play a positive role in the improvement of iron status and control of anaemia...

..When the HRE of rats fed FeII-S was 100, that of rats fed BDF was approximately 80. These results suggest that BMD is an effective dietary source of iron...

..To examine the association between consumption of red and processed meat (RPM) and iron intakes and status in adults...

..Many of the strategies for enhancing the content and bioavailability of dietary iron are also appropriate for zinc.

..The data suggest that a high prevalence of IDA among children in areas of endemic goiter may reduce the effectiveness of iodine prophylaxis...

..The response was higher in initially anaemic infants. From a programmatic perspective, evidence needs to be generated on the relative merits of selective (anaemic) versus general supplementation and daily versus weekly supplementation...

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..The gateway for dietary iron to enter the cells lining the intestine is a protein called DMT1, which can also transport the toxic metal ..

..to test the hypotheses that Zip14 plays a role in the uptake of non-transferrin-bound iron by the liver and dietary iron by the intestine...

..The gateway for dietary iron to enter the cells lining the intestine is a protein called DMT1, which can also transport the toxic metal ..

..The gateway for dietary iron to enter the cells lining the intestine is a protein called DMT1, which can also transport the toxic metal ..

..Each transfusion contributes more than a year's dietary iron intake, producing toxic iron overload in many organ systems including the heart...

A sustainable solution to dietary iron deficiency can be achieved in part by increasing bioavailable iron in seeds used for food such as soybeans. Dietary iron deficiency and anemia afflict 1.5 billion people world-wide, approximately 6...

Alternatives to current management strategies for managing dietary iron deficiency can help compensate for the relative expense of food supplementation, for noncompliance with specific therapies and for interactions between supplements ..

..Hepcidin deficiency, which causes excessive dietary iron absorption and progressive tissue iron deposition and dysfunction, appears to be the common pathogenic ..

..in vivo effect of orally administered G-CSF-Tf fusion protein will also be examined in correlation with dietary iron levels. These data will provide information regarding the deposition, bioavailability, and transport mechanism...

..in vivo effect of orally administered G-CSF-Tf fusion protein will also be examined in correlation with dietary iron levels. These data will provide information regarding the deposition, bioavailability, and transport mechanism...

..in vivo effect of orally administered G-CSF-Tf fusion protein will also be examined in correlation with dietary iron levels. These data will provide information regarding the deposition, bioavailability, and transport mechanism...

..to test the hypotheses that Zip14 plays a role in the uptake of non-transferrin-bound iron by the liver and dietary iron by the intestine...

..Ferristatin also blocks iron uptake by DMT1, a ferrous iron transporter that functions in dietary iron absorption across the apical membrane of enterocytes and after iron delivery into endosomes by the transferrin-..

..patterns of progastrin expression and processing will be measured by radioimmunoassy in mice with altered dietary iron uptake, and in patients with hemochromatosis...

..patterns of progastrin expression and processing will be measured by radioimmunoassy in mice with altered dietary iron uptake, and in patients with hemochromatosis...

..In turn, hepcidin inhibits the intestinal absorption of dietary iron, as well as iron recycling by macrophages and iron release from hepatic stores...

..by hepatocytes and binds to ferroportin in cells that export iron to plasma: duodenal enterocytes that absorb dietary iron, macrophages that recycle senescent red cells, and hepatocytes that store iron...

..by hepatocytes and binds to ferroportin in cells that export iron to plasma: duodenal enterocytes that absorb dietary iron, macrophages that recycle senescent red cells, and hepatocytes that store iron...

..The long-term goal of this research is to understand the specific function of Cp in iron homeostasis, and especially its role in primary (genetic) and secondary (dietary) iron overload states. ..

..Affected individuals absorb excessive amounts of dietary iron and develop progressive accumulation of tissue iron stores with consequent organ dysfunction including hepatic ..

The final step of dietary iron assimilation - the exsorption of iron from the mucosa into circulation - involves the iron transport protein ferroportin...

..We have recently generated preliminary data suggesting that both increased neonatal dietary iron intake and decreases in SN levels of the thiol antioxidant glutathione result in aberrantly sustained IRP ..

..We have recently generated preliminary data suggesting that both increased neonatal dietary iron intake and decreases in SN levels of the thiol antioxidant glutathione result in aberrantly sustained IRP ..

..HH) is a common autosomal recessive disorder of iron metabolism characterized by excess absorption of dietary iron. HH is caused by mutation of HFE, a MHC class I-like protein found in stable association with Beta-2-..

..Despite the clinical prevalence of iron deficiency and iron overload, dietary iron uptake is poorly understood...

..due to overload of this toxic metal and therefore a reciprocal relationship exists between body iron stores and dietary iron absorption, although the molecular basis for ion homeostasis remains unknown...