rhodium

Summary

Summary: Rhodium. A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh. (Dorland, 28th ed)

Top Publications

  1. ncbi Asymmetric catalytic hydrogenation. Design of new Ru catalysts and chiral ligands: from laboratory to industrial applications
    Jean Pierre Genet
    Ecole Nationale Superieure de Chimie de Paris, Laboratoire de Synthese Selective Organique et Produits Naturels, 11 Rue P et M Curie, 75231 Paris Cedex 05, France
    Acc Chem Res 36:908-18. 2003
  2. pmc Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy
    Marcella L B Carneiro
    Instituto de Ciencias Biologicas, Universidade de Brasilia, Brazil, 70 919 970
    J Nanobiotechnology 9:11. 2011
  3. ncbi Direct electron transfer between cytochrome P450scc and gold nanoparticles on screen-printed rhodium-graphite electrodes
    Victoria V Shumyantseva
    Institute of Biomedical Chemistry, Pogodinskaya st 10, Moscow 119121, Russia
    Biosens Bioelectron 21:217-22. 2005
  4. ncbi Rhodium N-heterocyclic carbene-catalyzed [4 + 2] and [5 + 2] cycloaddition reactions
    Sang Ick Lee
    Intelligent Textile System Research Center, Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151 747, Korea
    J Org Chem 71:91-6. 2006
  5. doi Rhodium catalysed conjugate addition of a chiral alkenyltrifluoroborate salt: the enantioselective synthesis of hermitamides A and B
    Christopher G Frost
    Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
    Org Biomol Chem 6:4340-7. 2008
  6. doi Highly enantioselective and efficient synthesis of flavanones including pinostrobin through the rhodium-catalyzed asymmetric 1,4-addition
    Toshinobu Korenaga
    Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, 3 1 1 Tsushima naka, Okayama 700 8530, Japan
    Org Lett 13:2022-5. 2011
  7. ncbi Selective tryptophan modification with rhodium carbenoids in aqueous solution
    John M Antos
    Department of Chemistry, University of California, Berkeley, CA 94720 1460, USA
    J Am Chem Soc 126:10256-7. 2004
  8. ncbi Covalent binding and interstrand cross-linking of duplex DNA by dirhodium(II,II) carboxylate compounds
    Shari U Dunham
    Department of Chemistry, Colby College, Waterville, Maine 04901, USA
    Biochemistry 44:996-1003. 2005
  9. doi Cell-selective, apoptosis-inducing rhodium(III) crown thiaether complexes
    Ruth Bieda
    Lehrstuhl fur Analytische Chemie, Ruhr Universitat Bochum, 44780 Bochum, Germany
    ChemMedChem 5:1123-33. 2010
  10. doi Conformational studies on chiral rhodium complexes by ECD and VCD spectroscopy
    Gábor Szilvágyi
    Laboratory for Chiroptical Structure Analysis, Institute of Chemistry, Eotvos Lorand University, Budapest, Hungary
    Chirality 23:294-9. 2011

Detail Information

Publications279 found, 100 shown here

  1. ncbi Asymmetric catalytic hydrogenation. Design of new Ru catalysts and chiral ligands: from laboratory to industrial applications
    Jean Pierre Genet
    Ecole Nationale Superieure de Chimie de Paris, Laboratoire de Synthese Selective Organique et Produits Naturels, 11 Rue P et M Curie, 75231 Paris Cedex 05, France
    Acc Chem Res 36:908-18. 2003
    ..Applications of these ligands to rhodium- and ruthenium-mediated hydrogenation of ketones and olefins have been reported with high enantioselectivities...
  2. pmc Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy
    Marcella L B Carneiro
    Instituto de Ciencias Biologicas, Universidade de Brasilia, Brazil, 70 919 970
    J Nanobiotechnology 9:11. 2011
    b>Rhodium (II) citrate (Rh(2)(H(2)cit)(4)) has significant antitumor, cytotoxic, and cytostatic activity on Ehrlich ascite tumor...
  3. ncbi Direct electron transfer between cytochrome P450scc and gold nanoparticles on screen-printed rhodium-graphite electrodes
    Victoria V Shumyantseva
    Institute of Biomedical Chemistry, Pogodinskaya st 10, Moscow 119121, Russia
    Biosens Bioelectron 21:217-22. 2005
    ..an investigation of electron transfer between cytochrome P450scc (CYP11A1) and gold nanoparticles immobilised on rhodium-graphite electrodes...
  4. ncbi Rhodium N-heterocyclic carbene-catalyzed [4 + 2] and [5 + 2] cycloaddition reactions
    Sang Ick Lee
    Intelligent Textile System Research Center, Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151 747, Korea
    J Org Chem 71:91-6. 2006
    reactions: see text] A rhodium complex of N-heterocyclic carbene (NHC) has been developed for intra- and intermolecular [4 + 2] and intramolecular [5 + 2] cycloaddition reactions...
  5. doi Rhodium catalysed conjugate addition of a chiral alkenyltrifluoroborate salt: the enantioselective synthesis of hermitamides A and B
    Christopher G Frost
    Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
    Org Biomol Chem 6:4340-7. 2008
    The concise enantioselective synthesis of hermitamides A and B is presented utilising a rhodium catalysed conjugate addition reaction to introduce the side chain and chiral information in a single step via an alkenyltrifluoroborate salt.
  6. doi Highly enantioselective and efficient synthesis of flavanones including pinostrobin through the rhodium-catalyzed asymmetric 1,4-addition
    Toshinobu Korenaga
    Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, 3 1 1 Tsushima naka, Okayama 700 8530, Japan
    Org Lett 13:2022-5. 2011
    ..In this reaction, the 1,2-addition to (S)-1 frequently occurred to yield (2S,4R)-2,4-diaryl-4-chromanol as a byproduct, which could be reduced by changing the reaction solvent to CH(2)Cl(2) to deactivate the Rh catalyst (3% required)...
  7. ncbi Selective tryptophan modification with rhodium carbenoids in aqueous solution
    John M Antos
    Department of Chemistry, University of California, Berkeley, CA 94720 1460, USA
    J Am Chem Soc 126:10256-7. 2004
    ..It was also demonstrated that myoblobin concentrations as low as 10 muM still led to appreciable levels of modification. Reconstitution experiments confirmed that myoglobin retained its ability to bind heme following modification...
  8. ncbi Covalent binding and interstrand cross-linking of duplex DNA by dirhodium(II,II) carboxylate compounds
    Shari U Dunham
    Department of Chemistry, Colby College, Waterville, Maine 04901, USA
    Biochemistry 44:996-1003. 2005
    ..Since all three dirhodium compounds form covalent Rh-DNA adducts, including interstrand cross-links, it is important that DNA be considered a potential target for biological activity of these dirhodium carboxylate compounds...
  9. doi Cell-selective, apoptosis-inducing rhodium(III) crown thiaether complexes
    Ruth Bieda
    Lehrstuhl fur Analytische Chemie, Ruhr Universitat Bochum, 44780 Bochum, Germany
    ChemMedChem 5:1123-33. 2010
    Half-sandwich rhodium(III) polypyridyl (pp) complexes with the metal atom capped by the facial crown thiaether 1,4,7-trithiacyclononane [9]aneS(3) represent a promising class of apoptosis-inducing potent cytostatic agents...
  10. doi Conformational studies on chiral rhodium complexes by ECD and VCD spectroscopy
    Gábor Szilvágyi
    Laboratory for Chiroptical Structure Analysis, Institute of Chemistry, Eotvos Lorand University, Budapest, Hungary
    Chirality 23:294-9. 2011
    ..The combination of the VCD and ECD spectroscopic methods led us to the structural characterization of the complexes...
  11. pmc Expedient synthesis of N-acyl anthranilamides and β-enamine amides by the Rh(III)-catalyzed amidation of aryl and vinyl C-H bonds with isocyanates
    Kevin D Hesp
    Department of Chemistry, Yale University, New Haven, Connecticut 06520, USA
    J Am Chem Soc 133:11430-3. 2011
    ..This method provides direct and efficient syntheses of N-acyl anthranilamides, enamine amides, and pyrimidin-4-one heterocycles...
  12. doi Antileukemic activity and cellular effects of rhodium(III) crown thiaether complexes
    Ruth Bieda
    Lehrstuhl fur Analytische Chemie, Ruhr Universitat Bochum, 44780 Bochum, Germany
    Biometals 24:645-61. 2011
    The cytostatic properties of novel rhodium(III) thiacrown ether complexes [RhCl(LL)([9]aneS(3))](n+) with either aromatic κ(2)N ligands (n = 2) or anionic chelate ligands (n = 1) have been investigated for the human cancer cell lines HT-..
  13. pmc Rh(III)-catalyzed regioselective synthesis of pyridines from alkenes and α,β-unsaturated oxime esters
    Jamie M Neely
    Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States
    J Am Chem Soc 135:66-9. 2013
    ..Mechanistic studies suggest that heterocycle formation proceeds via reversible C-H activation, alkene insertion, and a C-N bond formation/N-O bond cleavage process...
  14. ncbi Cytogenetic and oxidative damage induced in human lymphocytes by platinum, rhodium and palladium compounds
    Lucia Migliore
    Dipartimento di Scienze dell Uomo e dell Ambiente, University of Pisa, Via S Giuseppe 22, 56126 Pisa, Italy
    Mutagenesis 17:411-7. 2002
    This study of soluble compounds of platinum, palladium and rhodium investigated the genotoxic properties of (NH(4))(2)PtCl(4), PtCl(2), PtCl(4), (NH(4))(2)PdCl(4), PdCl(2) and RhCl(3) using the human lymphocyte micronucleus (MN) assay ..
  15. ncbi Molybdenum, rhodium, and tungsten anode spectral models using interpolating polynomials with application to mammography
    J M Boone
    Department of Radiology, University of California, Davis, UC Davis Medical Center, Sacramento 95817, USA
    Med Phys 24:1863-74. 1997
    ..Using x-ray spectra measured for molybdenum, rhodium, and tungsten anode x-ray tubes at 13 different kV's (18, 20, 22, .....
  16. doi Tandem Rh(III)-catalyzed oxidative acylation of secondary benzamides with aldehydes and intramolecular cyclization: the direct synthesis of 3-hydroxyisoindolin-1-ones
    Satyasheel Sharma
    Department of Chemistry, University of Ulsan, Ulsan, 680 749, Republic of Korea
    Org Lett 14:906-9. 2012
    The rhodium-catalyzed oxidative acylation between secondary benzamides and aryl aldehydes via sp(2) C-H bond activation followed by an intramolecular cyclization is described...
  17. pmc Mechanism of the rhodium(III)-catalyzed arylation of imines via C-H bond functionalization: inhibition by substrate
    Michael E Tauchert
    Department of Chemistry, Yale University, New Haven, Connecticut 06520, USA
    J Am Chem Soc 134:1482-5. 2012
    ..The reaction was found to be first order in the catalyst resting state and inverse first order in the C-H activation substrate...
  18. ncbi Binding of DNA purine sites to dirhodium compounds probed by mass spectrometry
    Helen T Chifotides
    Chemistry Department and Laboratory for Biological Mass Spectrometry, Texas A and M University, College Station, Texas 77843, USA
    Inorg Chem 43:6177-87. 2004
    ..Ultimately, both MALDI and ESI MS proved to be complementary, valuable tools for probing the identity and stability of dinuclear metal-DNA adducts...
  19. doi N-Directing group assisted rhodium-catalyzed aryl C-H addition to aryl aldehydes
    Yang Li
    Beijing National Laboratory of Molecular Sciences BNLMS, College of Chemistry, Peking University, Beijing 100871, China
    Org Lett 14:636-9. 2012
    ..The method is highly atom-, step-, and redox-economic. The procedure is robust, reliable, and compatible with water and air...
  20. pmc Rhodium-catalyzed synthesis of branched amines by direct addition of benzamides to imines
    Kevin D Hesp
    Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States
    Org Lett 14:2304-7. 2012
    b>Rhodium-catalyzed addition of benzamide C-H bonds to a range of aromatic N-sulfonyl aldimines has been developed and proceeds with high functional group compatibility...
  21. pmc Biotinylated Rh(III) complexes in engineered streptavidin for accelerated asymmetric C-H activation
    Todd K Hyster
    Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA
    Science 338:500-3. 2012
    ..a glutamic acid or aspartic acid residue engineered into streptavidin acts in concert with a docked biotinylated rhodium(III) complex to enable catalytic asymmetric carbon-hydrogen (C-H) activation...
  22. ncbi A circular dichroism and fluorescence quenching study of the interactions between rhodium(II) complexes and human serum albumin
    B P Espósito
    Departamento de Quimica Fundamental, Universidade de Sao Paulo, Brazil
    J Inorg Biochem 75:55-61. 1999
    Various divalent rhodium complexes Rh2(L)4 (L = acetate, propionate, butyrate, trifluoroacetate and trifluoroacetamidate) have been found to bind to non-defatted human serum albumin (HSA) at molar ratios about 8:1...
  23. doi Rhodium(III)-catalyzed arene and alkene C-H bond functionalization leading to indoles and pyrroles
    David R Stuart
    Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Canada K1N 6N5
    J Am Chem Soc 132:18326-39. 2010
    Recently, the rhodium(III)-complex [Cp*RhCl(2)](2) 1 has provided exciting opportunities for the efficient synthesis of aromatic heterocycles based on a rhodium-catalyzed C-H bond functionalization event...
  24. doi Mild and efficient H/D exchange of alkanes based on C-H activation catalyzed by rhodium on charcoal
    Tomohiro Maegawa
    Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, 5 6 1 Mitahora higashi Gifu 502 8585, Japan
    Angew Chem Int Ed Engl 47:5394-7. 2008
  25. ncbi Self-supported organometallic rhodium quinonoid nanocatalysts for stereoselective polymerization of phenylacetylene
    Kang Hyun Park
    Department of Chemistry, Sungkyunkwan University, Suwon 440 746, Korea
    J Am Chem Soc 128:8740-1. 2006
    ..self-supported organometallic nanocatalysts (ONs) were synthesized by treatment of the eta6-pi-hydroquinone rhodium complex [(1,4-hydroquinone)Rh(COD)]+ with Al(Oi-Pr)3...
  26. doi Rhodium-catalyzed oxidative ortho-acylation of benzamides with aldehydes: direct functionalization of the sp2 C-H bond
    Jihye Park
    Department of Chemistry, University of Ulsan, Ulsan, 680 749, Republic of Korea
    Org Lett 13:4390-3. 2011
    A rhodium-catalyzed oxidative acylation of benzamides with aryl aldehydes via direct sp(2) C-H bond cleavage is described...
  27. ncbi Rhodium catalyzed [4 + 2 + 2] cycloaddition and alkyne insertion: a new route to eight-membered rings
    Scott R Gilbertson
    Department of Chemistry, Washington University, Saint Louis, Missouri 63130, USA
    J Am Chem Soc 124:8784-5. 2002
    A novel variation of the rhodium catalyzed [4 + 2] reaction is reported. A catalyst system that forms an eight-membered ring product from the incorporation of an alkyne into a dienyne is discussed...
  28. ncbi Rhodium-catalyzed synthesis of eight-membered rings
    Brenton DeBoef
    Department of Chemistry, Washington University, One Brookings Drive, Saint Louis, Missouri 63130 4899, USA
    J Org Chem 72:799-804. 2007
    Experiments to develop a rhodium catalyst for the [4 + 2 + 2] cycloisomerization of dienynes with a second alkyne are described. The generality of the reaction is probed in terms of dienyne structure and alkyne structure...
  29. pmc Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells
    Russell J Ernst
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States
    Biochemistry 50:10919-28. 2011
    ..b>Rhodium metalloinsertors bind to DNA mismatches with high affinity and specificity and represent a promising strategy to ..
  30. pmc Rhodium(III)-catalyzed arylation of Boc-imines via C-H bond functionalization
    Andy S Tsai
    Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States
    J Am Chem Soc 133:1248-50. 2011
    The first rhodium-catalyzed arylation of imines proceeding via C-H bond functionalization is reported. Use of a non-coordinating halide abstractor is important to obtain reactivity...
  31. doi Occupational immediate-type asthma and rhinitis due to rhodium salts
    Rolf Merget
    Research Institute of Occupational Medicine, German Social Accident Insurance BGFA, Ruhr University, Burkle de la Camp Platz 1, Bochum, Germany
    Am J Ind Med 53:42-6. 2010
    Whereas platinum salts are well known occupational allergens, rhodium salts have not been identified as inhalative sensitizing substances.
  32. pmc A bulky rhodium complex bound to an adenosine-adenosine DNA mismatch: general architecture of the metalloinsertion binding mode
    Brian M Zeglis
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Biochemistry 48:4247-53. 2009
    ..In both structures, the bulky rhodium complex inserts into the two mismatched sites from the minor groove side, ejecting the mismatched bases into the ..
  33. doi Rhodium(III)-catalyzed isoquinolone synthesis: the N-O bond as a handle for C-N bond formation and catalyst turnover
    Nicolas Guimond
    Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario K1N 6N5, Canada
    J Am Chem Soc 132:6908-9. 2010
    ..Mechanistic studies point out the important involvement of a N-O bond as a tool for C-N bond formation and catalyst turnover...
  34. pmc DNA mismatch binding and antiproliferative activity of rhodium metalloinsertors
    Russell J Ernst
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    J Am Chem Soc 131:2359-66. 2009
    Deficiencies in mismatch repair (MMR) are associated with carcinogenesis. Rhodium metalloinsertors bind to DNA base mismatches with high specificity and inhibit cellular proliferation preferentially in MMR-deficient cells versus MMR-..
  35. ncbi Application of chiral mixed phosphorus/sulfur ligands to enantioselective rhodium-catalyzed dehydroamino acid hydrogenation and ketone hydrosilylation processes
    David A Evans
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    J Am Chem Soc 125:3534-43. 2003
    ....
  36. pmc Insights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalator
    Valérie C Pierre
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 104:429-34. 2007
    We report the 1.1-A resolution crystal structure of a bulky rhodium complex bound to two different DNA sites, mismatched and matched in the oligonucleotide 5'-(dCGGAAATTCCCG)2-3'...
  37. ncbi Encapsulation and release of rhodium(II) citrate and its association complex with hydroxypropyl-beta-cyclodextrin from biodegradable polymer microspheres
    R D Sinisterra
    Chemical Engineering Department, Massachusetts Institute of Technology, 45 Carleton Street, Bldg E25, Rm 342, Cambridge, Massachusetts 02139, USA
    J Pharm Sci 88:574-6. 1999
    b>Rhodium(II) carboxylates and their derivatives constitute a promising class of second-generation transition metal compounds with anticancer properties...
  38. ncbi Rhodium and its compounds as potential agents in cancer treatment
    N Katsaros
    National Centre of Scientific Research Demokritos, Institute of Physical Chemistry, Agia Paraskevi Attikis, Greece
    Crit Rev Oncol Hematol 42:297-308. 2002
    ..b>Rhodium belongs to the same group as platinum and ruthenium...
  39. ncbi Isotope effects and the nature of selectivity in rhodium-catalyzed cyclopropanations
    Daniel T Nowlan
    Department of Chemistry, Texas A and M University, P O Box 30012, College Station, Texas 77842, USA
    J Am Chem Soc 125:15902-11. 2003
    ..functional theory calculations (B3LYP) predict a reaction pathway involving complexation of the diazoesters to rhodium, loss of N(2) to afford a rhodium carbenoid, and an asynchronous but concerted cyclopropanation transition state...
  40. doi Synthesis, biological activity, and structure-activity relationships for potent cytotoxic rhodium(III) polypyridyl complexes
    Melanie Harlos
    Lehrstuhl fur Analytische Chemie, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    J Med Chem 51:3924-33. 2008
    ..Treatment of HT-29 and MCF-7 cells with 3a leads to significant decreases in cellular oxygen consumption and the rate of extracellular acidification...
  41. ncbi Synthesis of 1,2-diheteroatom-substituted alkenes via rhodium-catalyzed intramolecular hydrogen transfer
    M Mar Diaz-Requejo
    Department of Chemistry, University of North Carolina at Chapel Hill, CB 3290 Venable Hall, Chapel Hill, North Carolina 27599 3290, USA
    J Am Chem Soc 125:2038-9. 2003
    ..We describe here a simple catalytic procedure based on rhodium C-H bond activation for the synthesis of diheteroatom alkenes of the type R(3)SiOCH=CHG (G = -OR, -NRR').
  42. ncbi Comparison of the anti-neoplastic effects of dirhodium(II) tetrapropionate and its adducts with nicotinate and isonicotinate anions in mice bearing Ehrlich tumors
    Aparecido Ribeiro de Souza
    Instituto de Quimica, Universidade Federal de Goias, Campus Samambaia, CP 131, 74001 970 Goiania, GO, Brazil
    Eur J Med Chem 41:1214-6. 2006
    b>Rhodium(II) propionate, [Rh2(prop)4], and its adduct with nicotinate (nic-) and isonicotinate (isonic-) anions, [Rh2(prop)4(nic)2](2-) and [Rh2(prop)4(isonic)2](2-), respectively, were prepared for study...
  43. ncbi Controlled release of rhodium (II) carboxylates and their association complexes with cyclodextrins from hydroxyapatite matrix
    A E Burgos
    Departamento de Química ICEx, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
    Biomaterials 23:2519-26. 2002
    Preparation and characterization of a controlled release system of rhodium (II) citrate, acetate. propionate, butyrate and their inclusion or association compounds with cyclodextrin (CD) are described...
  44. pmc A rhodium(III) complex for high-affinity DNA base-pair mismatch recognition
    Henrik Junicke
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 100:3737-42. 2003
    A rhodium(III) complex, rac-[Rh(bpy)(2)phzi](3+) (bpy, 2,2'-bipyridine; phzi, benzo[a]phenazine-5,6-quinone diimine) has been designed as a sterically demanding intercalator targeted to destabilized mismatched sites in double-helical DNA...
  45. ncbi Dirhodium(II,II) complexes: molecular characteristics that affect in vitro activity
    Alfredo M Angeles-Boza
    Department of Chemistry, The Ohio State University, Columbus, Ohio 43210, USA
    J Med Chem 49:6841-7. 2006
    ..The toxicities of complexes 1-8 are not related to their charge or the ease by which they transverse the cellular membrane but to the lability of the ligands on the dirhodium core...
  46. ncbi Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta
    Marina Bakhtina
    Department of Chemistry and Biochemistry and Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, USA
    Biochemistry 44:5177-87. 2005
    ..The methodologies can be used to examine other DNA polymerases to answer whether the properties of Pol beta are exceptional or general...
  47. ncbi Different effects of platinum, palladium, and rhodium salts on lymphocyte proliferation and cytokine release
    Paolo Boscolo
    Department of Medicine and Science of Ageing, G D Annunzio University of Chieti and Pescara, Italy
    Ann Clin Lab Sci 34:299-306. 2004
    ....
  48. ncbi Artificial metalloenzymes: (strept)avidin as host for enantioselective hydrogenation by achiral biotinylated rhodium-diphosphine complexes
    Myriem Skander
    Institute of Chemistry, University of Neuchatel, Avenue Bellevaux 51, CP2, CH 2007 Neuchatel, Switzerland
    J Am Chem Soc 126:14411-8. 2004
    We report on the generation of artificial metalloenzymes based on the noncovalent incorporation of biotinylated rhodium-diphosphine complexes in (strept)avidin as host proteins...
  49. doi Domino reactions of rhodium(II) carbenoids for alkaloid synthesis
    Albert Padwa
    Department of Chemistry, Atlanta, GA, USA
    Chem Soc Rev 38:3072-81. 2009
    In this tutorial review, the rhodium(II)-catalyzed domino reactions of alpha-diazo carbonyl compounds are summarized...
  50. ncbi A mismatch-selective bifunctional rhodium-Oregon Green conjugate: a fluorescent probe for mismatched DNA
    Brian M Zeglis
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    J Am Chem Soc 128:5654-5. 2006
    ....
  51. doi Synthesis of phthalocyanine stabilized rhodium nanoparticles and their application in biosensing of cytochrome c
    K S Lokesh
    Govt Science College, Hassan, Karnataka, India
    Bioelectrochemistry 75:104-9. 2009
    A single step synthesis route is described for the preparation of rhodium nanoparticles using a cobalt aminophthalocyanine macrocyclic complex as a stabilizer...
  52. pmc DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications
    Brian M Zeglis
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    Nat Protoc 2:357-71. 2007
    ..The synthesis of the metallointercalators requires approximately 5-7 d. The mismatch- and SNP-detection experiments each require approximately 3 d...
  53. pmc DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators
    Jonathan R Hart
    Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena, CA 91125, USA
    Proc Natl Acad Sci U S A 103:15359-63. 2006
    ..Bulky rhodium intercalators target DNA base mismatches with high specificity...
  54. pmc Insertion of a bulky rhodium complex into a DNA cytosine-cytosine mismatch: an NMR solution study
    Christine Cordier
    Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
    J Am Chem Soc 129:12287-95. 2007
    ..These results corroborate those obtained crystallographically and, importantly, provide structural evidence for this specific insertion mode in solution...
  55. ncbi Enantioselective rhodium-catalyzed [2+2+2] cycloaddition of alkenyl isocyanates and terminal alkynes: application to the total synthesis of (+)-lasubine II
    Robert T Yu
    Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA
    J Am Chem Soc 128:12370-1. 2006
    The use of TADDOL-based phosphoramidite ligands on rhodium allows for the incorporation of terminal alkynes in the [2+2+2] cycloaddition with alkenyl isocyanates...
  56. ncbi Rhodium-catalyzed ring-opening reactions of N-boc-azabenzonorbornadienes with amine nucleophiles
    Yong hwan Cho
    Davenport Laboratories, Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5H 3H6
    J Am Chem Soc 128:6837-46. 2006
    In the presence of a rhodium catalyst (5 mol %) generated in situ from [Rh(cod)Cl](2) and (S,S')-(R,R')-C(2)-ferriphos (4a), the asymmetric ring-opening reaction of azabenzonorbornadienes (1a-m) with various aliphatic and aromatic amines ..
  57. ncbi Radiosensitization of CHO cells by two novel rhodium complexes under oxic and hypoxic conditions
    Nadia Falzone
    Department of Biomedical Sciences, Tswhane University of Technology, Pretoria, South Africa
    Anticancer Res 26:147-52. 2006
    ..Tumour hypoxia severely limits the success of radiotherapy. Radiosensitization of hypoxic tumour cells by drugs is thus an important clinical issue...
  58. pmc A chiral rhodium carboxamidate catalyst for enantioselective C-H amination
    David N Zalatan
    Department of Chemistry, Stanford University, Stanford, California 94305 5080, USA
    J Am Chem Soc 130:9220-1. 2008
    ..In addition, Rh2(S-nap)4 is found to promote chemoselective allylic C-H oxidation of unsaturated sulfamates, a property not observed with other dirhodium complexes tested to date...
  59. ncbi Cytotoxicity and cell death pathways invoked by two new rhodium-ferrocene complexes in benign and malignant prostatic cell lines
    Brandon Weber
    Department of Radiation Oncology, University of Stellenbosch, Tygerberg, SA
    Anticancer Res 24:763-70. 2004
    ..This investigation explores the onset of apoptosis and abnormal morphology in response to 3 drugs i.e. Cisplatin, a novel Ferrocene (fctfa) and a novel Rhodium-Ferrocene [Rh(fctfa)(cod)] complex.
  60. ncbi N-tosyloxycarbamates as a source of metal nitrenes: rhodium-catalyzed C-H insertion and aziridination reactions
    Hélène Lebel
    Departement de Chimie, Universite de Montreal, C P 6128, Succursale Centre Ville, Montreal, Quebec, Canada H3C 3J7
    J Am Chem Soc 127:14198-9. 2005
    The rhodium-catalyzed decomposition of N-tosyloxycarbamates to generate metal nitrenes which undergo intramolecular C-H insertion or aziridination reaction is described...
  61. ncbi Asymmetric induction in hydrogen-mediated reductive aldol additions to alpha-amino aldehydes catalyzed by rhodium: selective formation of syn-stereotriads directed by intramolecular hydrogen-bonding
    Cheol Kyu Jung
    Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX 78712, USA
    J Am Chem Soc 128:17051-6. 2006
    b>Rhodium-catalyzed hydrogenation of methyl vinyl ketone and ethyl vinyl ketone in the presence of N-Boc-alpha-aminoaldehydes 3a-8a at ambient temperature and pressure results in reductive C-C coupling to furnish aldol adducts 3b-8b and 3c-..
  62. pmc Rhodium(I)-catalyzed allenic carbocyclization reaction affording delta- and epsilon-lactams
    Kay M Brummond
    Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Org Lett 9:347-9. 2007
    This letter extends the scope of the rhodium(I)-catalyzed allenic Alder-ene carbocyclization reaction to the preparation of delta- and epsilon-lactams from amides...
  63. ncbi Rh III- and Ir III-catalyzed asymmetric transfer hydrogenation of ketones in water
    Xiaofeng Wu
    Liverpool Centre for Materials and Catalysis, Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK
    Chemistry 14:2209-22. 2008
    ..The aqueous phase reduction is simple, efficient and environmentally benign, thus presenting a viable alternative for asymmetric reduction...
  64. doi Efficient amide-directed catalytic asymmetric hydroboration
    Sean M Smith
    Department of Chemistry, University of Nebraska Lincoln, Lincoln, Nebraska 68588 0304, USA
    J Am Chem Soc 130:3734-5. 2008
    ..beta,gamma-unsaturated amides are shown to undergo highly regio- (>95%) and enantioselective (93-99% ee) rhodium-catalyzed hydroboration with pinacolborane (PinBH) using simple chiral monophosphite or phosphoramidite ligands ..
  65. pmc Asymmetric synthesis of bicyclic amidines via rhodium-catalyzed [2+2+2] cycloaddition of carbodiimides
    Robert T Yu
    Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA
    J Am Chem Soc 130:3262-3. 2008
  66. ncbi Rhodium-catalyzed arylative and alkenylative cyclization of 1,5-enynes induced by geminal carbometalation of alkynes
    Yiyun Chen
    Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA
    J Am Chem Soc 128:15598-9. 2006
    A rhodium(I)-catalyzed addition-cyclization of 1,5-enynes with aryl- and alkenylboronic acids has been developed...
  67. doi A carbonyl ylide cycloaddition approach to platensimycin
    Chan Hyuk Kim
    Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151 747, Korea
    Angew Chem Int Ed Engl 47:4009-11. 2008
  68. doi A theoretical study on the trans-addition intramolecular hydroacylation of 4-alkynals catalyzed by cationic rhodium complexes
    Lung Wa Chung
    Department of Chemistry and Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China
    J Org Chem 73:2649-55. 2008
    ..The role of a coordinating acetone solvent in the formation of cyclopentenone product is also discussed...
  69. doi BINOL-derived phosphoramidites in asymmetric hydrogenation: can the presence of a functionality in the amino group influence the catalytic outcome?
    Luc Eberhardt
    Laboratoire de Chimie Inorganique Moleculaire, Institut de Chimie, UMR 7177 CNRS Université Louis Pasteur, 1 rue Blaise Pascal, F 67008, Strasbourg Cedex, France
    Chem Soc Rev 37:839-64. 2008
    ..easily accessible monodentate chiral P(III) ligands turned out to provide high enantioselectivities when used in rhodium-catalysed olefin hydrogenation...
  70. ncbi Transition metal-mediated intramolecular [2+2+2] cycloisomerizations of cyclic triynes and enediynes
    Anna Torrent
    Department of Chemistry, Universitat de Girona, Campus de Montilivi, s n E 17071 Girona, Spain
    J Org Chem 70:2033-41. 2005
    ..Among them, the RhCl(CO)(PPh(3))(2) complex was found to catalyze the cycloisomerization reaction giving the desired cycloadducts in high yields...
  71. ncbi Bis-(2,5-diphenylphospholanes) with sp2 carbon linkers: synthesis and application in asymmetric hydrogenation
    Martin E Fox
    Dowpharma, Chirotech Technology Ltd, A Subsidiary of The Dow Chemical Company, Unit 162 Cambridge Science Park, Milton Road, Cambridge, CB4 0GH, UK
    J Org Chem 73:775-84. 2008
    ..maleic anhydride ((S,S)-Ph-MalPhos), and 1,1'-ferrocene ((S,S)-Ph-5-Fc) were synthesized, and their cationic [rhodium(I)(COD)] complexes were prepared...
  72. ncbi Synthesis of new chiral monodentate phosphite ligands and their use in catalytic asymmetric hydrogenation
    Zihao Hua
    Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794 3400, USA
    Org Lett 5:3831-4. 2003
    ..The new chiral ligand system is suitable to create libraries and possesses fine-tuning capability...
  73. doi Substituent effects, reactant preorganization, and ligand exchange control the reactivity in Rh(I)-catalyzed (5+2) cycloadditions between vinylcyclopropanes and alkynes
    Peng Liu
    Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095 1569, USA
    Angew Chem Int Ed Engl 47:3939-41. 2008
  74. doi Enantioselective syntheses of various chiral multicyclic compounds with quaternary carbon stereocenters by catalytic intramolecular cycloaddition
    Takanori Shibata
    Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku, Tokyo, 169 8555, Japan
    J Am Chem Soc 130:3451-7. 2008
    ..4-6), where alkyne and alkene moieties are connected by a 1,1-disubstituted alkene, was examined using a chiral rhodium catalyst, and various types of cycloadducts with quaternary carbon stereocenter(s) were obtained in high to ..
  75. pmc Diastereo- and enantioselective hydrogenative aldol coupling of vinyl ketones: design of effective monodentate TADDOL-like phosphonite ligands
    Cisco Bee
    University of Texas at Austin, Department of Chemistry and Biochemistry, Austin, Texas 78712, USA
    J Am Chem Soc 130:2746-7. 2008
    ..available methyl vinyl ketone (MVK) or ethyl vinyl ketone (EVK) in the presence of aldehydes 1a-7a using cationic rhodium catalysts modified by chiral TADDOL-like phosphonite ligands AP-I and AP-IV produces aldol adducts 1b-7b and 1c-..
  76. ncbi Asymmetric hydrogenation of unsaturated ureas with the BIPI ligands
    Carl A Busacca
    Department of Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc, 900 Ridgebury Road, Ridgefield, Connecticut 06877, USA
    Org Lett 10:341-4. 2008
    ..Optimization of the P-N ligand structure has led to the development of chiral rhodium catalysts capable of producing the targets with >99% ee...
  77. ncbi Theoretical elucidation of the rhodium-catalyzed [4 + 2] annulation reactions
    Cai Yun Geng
    State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130023, People s Republic of China
    J Comput Chem 29:686-93. 2008
    ....
  78. ncbi Stereochemical features making deoxycholic acid derived tropos biphenylphosphites efficient chiral ligands for rhodium: the asymmetric hydrogenation of dimethylitaconate as a case study
    Anna Iuliano
    Dipartimento di Chimica e Chimica Industriale, Universita di Pisa, Via Risorgimento 35, 56126 Pisa, Italy
    J Org Chem 72:8472-7. 2007
    ..acid derived biphenylphosphites, whose tropos nature was ascertained by NMR and CD measurements, were used in the rhodium-catalyzed asymmetric hydrogenation of dimethylitaconate achieving enantiomeric excesses up to 91%...
  79. ncbi Rh-catalyzed asymmetric hydrogenation of gamma-phthalimido-substituted alpha,beta-unsaturated carboxylic acid esters: an efficient enantioselective synthesis of beta-aryl-gamma-amino acids
    Jun Deng
    Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
    Org Lett 9:4825-8. 2007
    ..The method has been applied successfully to the synthesis of several chiral pharmaceuticals including (R)-baclofen and (R)-rolipram with high enantioselectivities...
  80. ncbi Rh-catalyzed highly enantioselective formation of functionalized cyclopentanes and cyclopentanones
    Fei Liu
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P R China
    Org Biomol Chem 5:3531-4. 2007
    ..were obtained from readily available starting materials in high yields and selectivities. Both regioselectivities and enantioselectivities are excellent: only 1,4-dienes were observed and in over 99% ee...
  81. ncbi Balance between allylic C-H activation and cyclopropanation in the reactions of donor/acceptor-substituted rhodium carbenoids with trans-alkenes
    Huw M L Davies
    Department of Chemistry, University of Buffalo, The State University of New York, Buffalo, New York 14260 3000, USA
    Org Lett 9:4971-4. 2007
    b>Rhodium(II)-catalyzed reactions of aryldiazoacetates with (E)-aryl-substituted alkenes generate C-H insertion products and/or cyclopropanes...
  82. ncbi Addition of alkynes to aldehydes and activated ketones catalyzed by rhodium-phosphine complexes
    Pawan K Dhondi
    Department of Chemistry, 1 014 Center for Science and Technology, Syracuse University, Syracuse, New York 13244, USA
    J Org Chem 72:9590-6. 2007
    A mixture of 2-(di-tert-butylphosphino)biphenyl and dicarbonylacetonato rhodium(I) provides an effective catalyst system for the addition of alkynes to aldehydes and activated ketones...
  83. ncbi Rhodium-complex-catalyzed asymmetric hydrogenation: transformation of precatalysts into active species
    Angelika Preetz
    Leibniz Institut fur Katalyse e V an der Universitat Rostock, Albert Einstein Strasse 29a, Germany
    Chemistry 14:1445-51. 2008
    The use of diolefin-containing rhodium precatalysts leads to induction periods in asymmetric hydrogenation of prochiral olefins. Consequently, the reaction rate increases in the beginning...
  84. ncbi Exploiting self-assembly for ligand-scaffold optimization: substrate-tailored ligands for efficient catalytic asymmetric hydroboration
    Shin A Moteki
    Department of Chemistry, University of Nebraska Lincoln, Lincoln, NE 68588 0304, USA
    Angew Chem Int Ed Engl 47:894-7. 2008
  85. ncbi A rhodium(I)-catalyzed demethylation-cyclization of o-anisole-substituted ynamides in the synthesis of chiral 2-amido benzofurans
    Jossian Oppenheimer
    Division of Pharmaceutical Sciencies and Department of Chemistry, University of Wisconsin Madison, Rennebohm Hall, 777 Highland Avenue, Madison, Wisconsin 53705 2222, USA
    Org Lett 9:2361-4. 2007
    ..A Rh(I)-catalyzed demethylation-cyclization sequence for a direct transformation of o-anisole-substituted ynamides to benzofurans is described here. The Ag salt functions synergistically with Rh(I) for the key demethylation step...
  86. doi Origins of differences in reactivities of alkenes, alkynes, and allenes in [Rh(CO)2Cl]2-catalyzed (5 + 2) cycloaddition reactions with vinylcyclopropanes
    Zhi Xiang Yu
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry, Peking University, Beijing 100871, PR China
    J Am Chem Soc 130:2378-9. 2008
  87. pmc Rh(I)-catalyzed arylation of heterocycles via C-H bond activation: expanded scope through mechanistic insight
    Jared C Lewis
    Department of Chemistry, University of California and Division of Chemical Sciences, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    J Am Chem Soc 130:2493-500. 2008
    ..The reactions are performed with heating in a microwave reactor to obtain excellent product yields in 2 h...
  88. pmc The stereoselective formation of bicyclic enamines with bridgehead unsaturation via tandem C-H bond activation/alkenylation/electrocyclization
    Sirilata Yotphan
    Department of Chemistry, University of California, Berkeley, California 94720, USA
    J Am Chem Soc 130:2452-3. 2008
  89. ncbi Rh-catalyzed highly enantioselective synthesis of 3-arylbutanoic acids
    Xianfeng Sun
    Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA
    Angew Chem Int Ed Engl 46:2623-6. 2007
  90. ncbi Synthesis of densely functionalised arenes using [2 + 2 + 2] cycloaddition reactions
    Jonathan Clayden
    School of Chemistry, The University of Manchester, Oxford Road, Manchester, UK
    Org Biomol Chem 5:1028-30. 2007
    ..The diarylmethanes made in this way show no evidence in their NMR spectra, however, of rotational restriction...
  91. ncbi Hydrogen bonding makes a difference in the rhodium-catalyzed enantioselective hydrogenation using monodentate phosphoramidites
    Yan Liu
    State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry SIOC, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, PR China
    J Am Chem Soc 128:14212-3. 2006
    ..This finding provides a basis for design and development of further catalyst systems using this type of monodentate phosphoramidite ligands...
  92. ncbi Synthesis of 2,3-disubstituted indoles by a rhodium-catalyzed aromatic amino-Claisen rearrangement of N-propargyl anilines
    Akio Saito
    Laboratory of Organic Reaction Chemistry, Showa Pharmaceutical University, 3 3165 Higashi Tamagawagakuen, Machida, Tokyo 194 8543, Japan
    Angew Chem Int Ed Engl 46:3931-3. 2007
  93. doi Click-connected ligand scaffolds: macrocyclic chelates for asymmetric hydrogenation
    Qing Zhang
    Department of Chemistry, University of Nebraska Lincoln, Lincoln, Nebraska 68588 0304, USA
    Org Lett 10:545-8. 2008
    ..Enantioselectivity as high as 97% ee is obtained using these click ligands in rhodium-catalyzed asymmetric hydrogenation...
  94. ncbi Highly Enantio- and s-trans C=C bond selective catalytic hydrogenation of cyclic enones: alternative synthesis of (-)-menthol
    Takashi Ohshima
    Department of Chemistry, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560 8531, Japan
    Chemistry 14:2060-6. 2008
    ..Moreover, we found that the complete s-trans and s-cis C=C bond selective reactions were also realized by the proper choice of both the chiral ligands and halides...
  95. ncbi Highly enantioselective Rh-catalyzed hydrogenation based on phosphine-phosphite ligands derived from carbohydrates
    O Pàmies
    Departament de Quimica Fisica i Inorganica, Universitat Rovira i Virgili, Pl Imperial Tarraco 1, 43005 Tarragona, Spain
    J Org Chem 66:8364-9. 2001
    ..on intermediates of the catalytic cycle show that the [Rh(P(1)-P(2))(enamide)]BF(4) species is the resting state and that the rate dependence is first order in rhodium and hydrogen pressure and zero order in enamide concentration.
  96. ncbi Highly enantioselective asymmetric hydrogenation of beta-acetamido dehydroamino acid derivatives using a three-hindered quadrant rhodium catalyst
    He ping Wu
    Pfizer, Inc, 2800 Plymouth Road, Ann Arbor, Michigan 48105, USA
    Org Lett 6:3645-7. 2004
    reaction: see text] A previously reported three-hindered quadrant chiral ligand and its corresponding rhodium complex provide high enantioselectivity for the asymmetric hydrogenation of beta-acetamido dehydroamino acid substrates...
  97. ncbi A new dirhodium(II) carboxamidate complex as a chiral Lewis acid catalyst for enantioselective hetero-Diels-Alder reactions
    Masahiro Anada
    Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan
    Angew Chem Int Ed Engl 43:2665-8. 2004
  98. ncbi Artificial metalloenzymes for enantioselective catalysis based on the noncovalent incorporation of organometallic moieties in a host protein
    Thomas R Ward
    Institute of Chemistry, University of Neuchatel, Av Bellevaux 51, CP 2, 2007 Neuchatel, Switzerland
    Chemistry 11:3798-804. 2005
    ..Incorporation of achiral, biotinylated aminodiphosphine-rhodium complexes in (strept)avidin affords enantioselective hydrogenation catalysts...
  99. ncbi A bisphosphepine ligand with stereogenic phosphorus centers for the practical synthesis of beta-aryl-beta-amino acids by asymmetric hydrogenation
    Wenjun Tang
    Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA
    Angew Chem Int Ed Engl 42:3509-11. 2003
  100. ncbi Synthesis and application of phosphinoferrocenylaminophosphine ligands for asymmetric catalysis
    Neil W Boaz
    Research Laboratories, Eastman Chemical Company, P O Box 1972, Kingsport, Tennessee 37662, USA
    J Org Chem 70:1872-80. 2005
    ..The rhodium complexes of these ligands show exceedingly high enantioselectivities (generally >95% ee) and activities often ..
  101. ncbi A one-pot synthesis of (E)-disubstituted alkenes by a bimetallic [Rh-Pd]-catalyzed hydrosilylation/hiyama cross-coupling sequence
    Carine Thiot
    Laboratoire de Synthese Bio Organique, Universite Louis Pasteur, Faculte de Pharmacie, 74 route du Rhin, 67401 Illkirch Graffenstaden, France
    Chemistry 13:8971-8. 2007
    ..Its catalytic activity was evaluated by rhodium-catalyzed hydrosilylation (H), palladium-catalyzed Hiyama coupling (C), and in the one-pot hydrosilylation/Hiyama ..

Research Grants86

  1. Catalytic, Regioselective C-H Activation/Oxidation of Substituted Arenes
    Erin Burger; Fiscal Year: 2007
    ..Reports on highly regioselective rhodium (III) catalyzed reactions have also led us to propose the development of new methodology for the rhodium-..
  2. N-Heterocycles from Azides through Rhodium-Catalyzed Nitrenoid Transfer
    TOM DRIVER; Fiscal Year: 2009
    ..We also showcase our new methods in succinct syntheses of multiple drug resistance (MDR) reversal agents. ..
  3. N-Heterocycles from Azides through Rhodium-Catalyzed Nitrenoid Transfer
    TOM GREGORY DRIVER; Fiscal Year: 2010
    ..We also showcase our new methods in succinct syntheses of multiple drug resistance (MDR) reversal agents. ..
  4. N-Heterocycles from Azides through Rhodium-Catalyzed Nitrenoid Transfer
    TOM GREGORY DRIVER; Fiscal Year: 2010
    ..We also showcase our new methods in succinct syntheses of multiple drug resistance (MDR) reversal agents. ..
  5. Amidoglycosylation Reactions of Glycal Metallanitrenes
    Christian Rojas; Fiscal Year: 2007
    ..out this overall oxidation, in a process best catalyzed by dirhodium(II) carboxylates and apparently involving a rhodium-complexed acyl nitrene intermediate...
  6. Polymer Membrane Ion/Gas/Polyion Sensors: New Frontiers
    Mark E Meyerhoff; Fiscal Year: 2010
    ..commercial biomedical grade heparin preparations using potentiometric polyanion sensor technology;2) the use of rhodium (III) metalloporphyrin complexes as the most selective binding agents discovered to date for preparing ..
  7. DNA MEDIATED ELECTRON TRANSFER REACTIONS
    JACQUELINE BARTON; Fiscal Year: 2002
    ..The tethered intercalators include phenanthrene quinone diimine of rhodium, dipyridophenazine complexes of ruthenium and osmium, and ethidium...
  8. Use of Silyl Glyoxylates in Tandem Vinylation/Brook Rearrangement/Adol Reactions
    REBECCA CUELLAR; Fiscal Year: 2007
    ..g. tiglic aldehyde) followed by enantioselective hydroxyl-directed hydrogenation using cationic rhodium or iridium species; iv) utilize the aforementioned methodology in the most concise synthesis to date of the ..
  9. X-RAY STUDIES ON NUCLEIC ACID CONSTITUENTS
    Muttaiya Sundaralingam; Fiscal Year: 1990
    ..containing mixed ammine and aquo ligands, sulphur substitution in the phosphate and also to metal ions such as rhodium in addition to Cr3+, Zn2+, Mn2+, Co2+, Ca2+ and Mg2+...
  10. METAL CATALYZED CARBON - CARBON BOND FORMING REACTIONS
    JAMES TAKACS; Fiscal Year: 1993
    ..Studies directed toward development of rhodium-catalyzed tetraene carbocyclizations is also described...
  11. METAL PROBES AND DRUG BINDING TO DNA
    JACQUELINE BARTON; Fiscal Year: 1993
    ..b>Rhodium complexes containing novel ancillary ligands and the phenanthrenequinone diimine (phi) ligand will be prepared, ..
  12. DNA Charge Transport Chemistry & Biology
    Jacqueline K Barton; Fiscal Year: 2011
    ..examine the distance range over which oxidative damage is funneled to a control sequence in mitochondria using rhodium photooxidants to generate damage at distant sites...
  13. DNA Charge Transport Chemistry & Biology
    Jacqueline K Barton; Fiscal Year: 2010
    ..examine the distance range over which oxidative damage is funneled to a control sequence in mitochondria using rhodium photooxidants to generate damage at distant sites...
  14. SELECTIVE METHODS FOR SYNTHESIS WITH STRAINED MOLECULES AND CARBENOIDS
    Joseph M Fox; Fiscal Year: 2010
    ..goal of the proposed research is to develop selective methods for organic synthesis with strained molecules and rhodium carbenoids...
  15. SELECTIVE METHODS FOR SYNTHESIS WITH STRAINED MOLECULES AND CARBENOIDS
    Joseph M Fox; Fiscal Year: 2011
    ..goal of the proposed research is to develop selective methods for organic synthesis with strained molecules and rhodium carbenoids...
  16. NEW RHODIUM-CATALYZED ALLYLIC ALKYLATION REACTIONS
    P Evans; Fiscal Year: 2006
    The aim of the following proposal is the development of the regio- and enantiospecific rhodium-catalyzed allylic substitution as a general cross-coupling reaction, and the combination with free radical cyclization and novel metal-..
  17. TOTAL SYNTHESIS OF NATURAL PRODUCTS
    K Nicolaou; Fiscal Year: 2002
    ..for their total synthesis, one following an intramolecular Diels-Alder approach and the other involving a rhodium-catalyzed carbenoid generation and addition to a double bond followed by a divinylcyclopropane [3...
  18. HETEROCYCLIC RING COMPOUNDS FOR ALKALOID SYNTHESIS
    Albert Padwa; Fiscal Year: 2004
    ..The project will focus on using the rhodium catalyzed reaction of alpha-diazo carbonyl compounds as a method for generating a variety of 1,3-dipoles...
  19. METAL PROBES AND DRUG BINDING TO DNA
    JACQUELINE BARTON; Fiscal Year: 2007
    ..We have also designed bulky rhodium intercalators that specifically target single base mismatches in the DNA duplex through photoactivated strand ..
  20. METAL PROBES AND DRUG BINDING TO DNA
    Jacqueline K Barton; Fiscal Year: 2010
    ..We have also designed bulky rhodium intercalators that specifically target single base mismatches in the DMAduplex through photoactivated strand ..
  21. Self-Assembled Solutions to Asymmetric Hydrogenation
    JAMES TAKACS; Fiscal Year: 2005
    ..I application focuses on the design, preparation and evaluation of such libraries in five substrate classes of rhodium-catalyzed asymmetric hydrogenation...
  22. COMBINATORIAL SYNTHESIS OF PHOSPHINE LIGANDS
    Scott Gilbertson; Fiscal Year: 2002
    ..Initially three reactions will be screened, palladium catalyzed pi-allyl alkylation, the Heck reaction and a rhodium catalyzed [4+2] cycloisomerization reaction...
  23. COMBINATORIAL SYNTHESIS OF PHOSPHINE LIGANDS
    Scott Gilbertson; Fiscal Year: 2003
    ..Initially three reactions will be screened, palladium catalyzed pi-allyl alkylation, the Heck reaction and a rhodium catalyzed [4+2] cycloisomerization reaction...
  24. Tetrahydronaphthylamines as Medications for Drug Abuse
    PHILLIP PELPHREY; Fiscal Year: 2007
    ..The proposed synthetic strategy involves the use of a rhodium catalyzed, C-H insertion/Cope rearrangement-elimination reaction previously developed in the Davies laboratory to ..
  25. COMBINATORIAL SYNTHESIS OF PHOSPHINE LIGANDS
    Scott Gilbertson; Fiscal Year: 1999
    ..Initially three reactions will be screened, palladium catalyzed pi-allyl alkylation, the Heck reaction and a rhodium Catalyzed [4+2] cycloaddition reaction...
  26. SERT/NET Inhibitors as Medications for Drug Addiction
    James Manning; Fiscal Year: 2007
    ..The methodology to be used involves a rhodium catalyzed, tandem C-H insertion/Cope rearrangement reaction that has been previously developed to rapidly ..
  27. Application of C-H Activation to Natural Product Synthesis
    HUW M DAVIES; Fiscal Year: 2010
    ..This proposal is centered around a recently discovered highly stereoselective rhodium-catalyzed C-H activation process, the combined C-H activation/Cope rearrangement...
  28. Regio-and Enantioselective Hydroformylation of Olefins
    Andrew Duncan; Fiscal Year: 2003
    ..The research plan described herein proposes the use of well-defined Lewis acid-modified rhodium(I) catalysts for highly regio- and enantioselective hydroformylation of functionalized olefins...
  29. An Allenic Pauson-Khand Reaction, New Directions
    KAY BRUMMOND; Fiscal Year: 2006
    ..abstract_text> ..
  30. ALLENIC PAUSON KHAND REACTION--SYNTHETIC APPLICATIONS
    KAY BRUMMOND; Fiscal Year: 2002
    ..In addition, the attainment of chiral allenes by using chiral bases or bases in the presence of chiral ligands to effect the enantioselective deprotonation is proposed. ..