nickel

Summary

Summary: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.

Top Publications

  1. ncbi An overview of nickel-titanium alloys used in dentistry
    S A Thompson
    Department of Adult Dental Health, University of Wales College of Medicine, Cardiff, UK
    Int Endod J 33:297-310. 2000
  2. ncbi Discoloration and dissolution of titanium and titanium alloys with immersion in peroxide- or fluoride-containing solutions
    Tatsumi Noguchi
    Department of Dental Materials Science, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Dent Mater J 27:117-23. 2008
  3. ncbi Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel
    Marc Schmidt
    Department of Dermatology, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
    Nat Immunol 11:814-9. 2010
  4. ncbi Effects of nickel, chromate, and arsenite on histone 3 lysine methylation
    Xue Zhou
    Nelson Institute of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, NY 10987, USA
    Toxicol Appl Pharmacol 236:78-84. 2009
  5. ncbi Interplay of metal ions and urease
    Eric L Carter
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824 4320, USA
    Metallomics 1:207-21. 2009
  6. ncbi Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers
    Haobin Chen
    Department of Environmental Medicine, New York University of School of Medicine, New York, New York 10016, USA
    J Biol Chem 285:7374-83. 2010
  7. ncbi Constitutively elevated salicylic acid signals glutathione-mediated nickel tolerance in Thlaspi nickel hyperaccumulators
    John L Freeman
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, Indiana 47907, USA
    Plant Physiol 137:1082-91. 2005
  8. ncbi Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells
    Theodore A Slotkin
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Environ Health Perspect 117:587-96. 2009
  9. ncbi A novel class of modular transporters for vitamins in prokaryotes
    Dmitry A Rodionov
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Bacteriol 191:42-51. 2009
  10. ncbi Does the effect of PM10 on mortality depend on PM nickel and vanadium content? A reanalysis of the NMMAPS data
    Francesca Dominici
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21215, USA
    Environ Health Perspect 115:1701-3. 2007

Detail Information

Publications294 found, 100 shown here

  1. ncbi An overview of nickel-titanium alloys used in dentistry
    S A Thompson
    Department of Adult Dental Health, University of Wales College of Medicine, Cardiff, UK
    Int Endod J 33:297-310. 2000
    The nickel-titanium alloy Nitinol has been used in the manufacture of endodontic instruments in recent years. Nitinol alloys have greater strength and a lower modulus of elasticity compared with stainless steel alloys...
  2. ncbi Discoloration and dissolution of titanium and titanium alloys with immersion in peroxide- or fluoride-containing solutions
    Tatsumi Noguchi
    Department of Dental Materials Science, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Dent Mater J 27:117-23. 2008
    ..15Pd, Ti-6Al-4V, Ti-7Nb-6Al, and Ti-10Cu alloys showed remarkable discoloration and dissolution with immersion. On the contrary, Ti-20Cr alloy showed very little discoloration and dissolution in either solution...
  3. ncbi Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel
    Marc Schmidt
    Department of Dermatology, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
    Nat Immunol 11:814-9. 2010
    Allergies to nickel (Ni(2+)) are the most frequent cause of contact hypersensitivity (CHS) in industrialized countries. The efficient development of CHS requires both a T lymphocyte-specific signal and a proinflammatory signal...
  4. ncbi Effects of nickel, chromate, and arsenite on histone 3 lysine methylation
    Xue Zhou
    Nelson Institute of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, NY 10987, USA
    Toxicol Appl Pharmacol 236:78-84. 2009
    Occupational exposure to nickel (Ni), chromium (Cr), and arsenic (As) containing compounds has been associated with lung cancer and other adverse health effects...
  5. ncbi Interplay of metal ions and urease
    Eric L Carter
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824 4320, USA
    Metallomics 1:207-21. 2009
    Urease, the first enzyme to be crystallized, contains a dinuclear nickel metallocenter that catalyzes the decomposition of urea to produce ammonia, a reaction of great agricultural and medical importance...
  6. ncbi Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers
    Haobin Chen
    Department of Environmental Medicine, New York University of School of Medicine, New York, New York 10016, USA
    J Biol Chem 285:7374-83. 2010
    ..ABH2 as examples, we show that this family of dioxygenases is highly sensitive to inhibition by carcinogenic nickel ions...
  7. ncbi Constitutively elevated salicylic acid signals glutathione-mediated nickel tolerance in Thlaspi nickel hyperaccumulators
    John L Freeman
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, Indiana 47907, USA
    Plant Physiol 137:1082-91. 2005
    Progress is being made in understanding the biochemical and molecular basis of nickel (Ni)/zinc (Zn) hyperaccumulation in Thlaspi; however, the molecular signaling pathways that control these mechanisms are not understood...
  8. ncbi Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells
    Theodore A Slotkin
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Environ Health Perspect 117:587-96. 2009
    ..Oxidative stress and excitotoxicity underlie the developmental neurotoxicity of numerous chemicals...
  9. ncbi A novel class of modular transporters for vitamins in prokaryotes
    Dmitry A Rodionov
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Bacteriol 191:42-51. 2009
    ..The shared use of energy-coupling modules was experimentally confirmed for folate, thiamine, and riboflavin transporters. We propose the name energy-coupling factor transporters for the new class of membrane transporters...
  10. ncbi Does the effect of PM10 on mortality depend on PM nickel and vanadium content? A reanalysis of the NMMAPS data
    Francesca Dominici
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21215, USA
    Environ Health Perspect 115:1701-3. 2007
    ..They found that average concentrations of nickel or vanadium in PM2.5 (PM with aerodynamic diameter < 2...
  11. ncbi Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress
    Konstantin Salnikow
    NCI Frederick, National Institutes of Health, Frederick, Maryland 21702, USA
    J Biol Chem 279:40337-44. 2004
    Exposure of cells to carcinogenic compounds of nickel(II) and cobalt(II) causes activation of the HIF-1 transcription factor and up-regulates a battery of hypoxia-inducible genes...
  12. ncbi Elevated serum concentrations of cobalt, chromium, nickel, and manganese after metal-on-metal alloarthroplasty of the hip: a prospective randomized study
    Henrik Dahlstrand
    Department of Molecular Medicine and Surgery, Section of Orthopaedics, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    J Arthroplasty 24:837-45. 2009
    ..3-fold (95% confidence interval [CI], 9.4-21.2); chromium, 5.2-fold (CI, 3.5-7.0); nickel, 2.1-fold (CI, 1.2-3.0); and manganese, 1.6-fold (CI, 1.3-2.0)...
  13. ncbi Metallic haptens induce differential phenotype of human dendritic cells through activation of mitogen-activated protein kinase and NF-kappaB pathways
    Diane Antonios
    Univ Paris Sud, INSERM UMR S 749, Faculte de Pharmacie, 5 Rue Jean Baptiste Clement, 92296 Chatenay Malabry, France
    Toxicol In Vitro 23:227-34. 2009
    ..Our results show that both NiSO(4) and CoCl(2) activate similar signaling pathways that are playing different roles in DC maturation depending on the hapten used...
  14. ncbi Investigating heavy-metal hyperaccumulation using Thlaspi caerulescens as a model system
    Matthew J Milner
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
    Ann Bot 102:3-13. 2008
    ..widely studied for its remarkable properties to tolerate toxic levels of zinc (Zn), cadmium (Cd) and sometimes nickel (Ni) in the soil, and accumulate these metals to very high levels in the shoot...
  15. ncbi The Helicobacter pylori GroES cochaperonin HspA functions as a specialized nickel chaperone and sequestration protein through its unique C-terminal extension
    Kristine Schauer
    Institut Pasteur, Unité Postulante Pathogenèse de Helicobacter, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France
    J Bacteriol 192:1231-7. 2010
    The transition metal nickel plays a central role in the human gastric pathogen Helicobacter pylori because it is required for two enzymes indispensable for colonization, the nickel metalloenzyme urease and [NiFe] hydrogenase...
  16. ncbi The N-terminal arm of the Helicobacter pylori Ni2+-dependent transcription factor NikR is required for specific DNA binding
    Erin L Benanti
    Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
    J Biol Chem 282:20365-75. 2007
    ..arm is highly variable among NikR family members, and these results suggest that it is an adaptable structural feature that can tune the regulatory capabilities of NikR to the nickel physiology of the microbe in which it is found.
  17. ncbi Nickel homeostasis in Escherichia coli - the rcnR-rcnA efflux pathway and its linkage to NikR function
    Jeffrey S Iwig
    Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO 63110, USA
    Mol Microbiol 62:252-62. 2006
    The nickel physiology of Escherichia coli is dominated by its Ni-Fe hydrogenase isozymes, which are expressed under anaerobic growth conditions. Hydrogenase activity in E...
  18. ncbi Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells
    Haobin Chen
    Department of Environmental Medicine, New York University of School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Carcinogenesis 31:2136-44. 2010
    ..Previously, we reported that both hypoxia and nickel (an environmental carcinogen) increased global histone H3 lysine 9 methylation in cells through inhibiting a novel ..
  19. ncbi MrdH, a novel metal resistance determinant of Pseudomonas putida KT2440, is flanked by metal-inducible mobile genetic elements
    Adhikarla Haritha
    Department of Biochemistry, Osmania University, Hyderabad, India
    J Bacteriol 191:5976-87. 2009
    ..The metal resistance function of mrdH was identified by the ability to confer nickel resistance upon its complementation into rcnA mutant (a nickel- and cobalt-sensitive mutant) of Escherichia coli...
  20. ncbi Hydrogenases from methanogenic archaea, nickel, a novel cofactor, and H2 storage
    Rudolf K Thauer
    Max Planck Institute for Terrestrial Microbiology, D 35043 Marburg, Germany
    Annu Rev Biochem 79:507-36. 2010
    ..Under conditions of nickel limitation, some methanogens synthesize a nickel-independent [Fe]-hydrogenase (instead of F(420)-reducing [NiFe]-..
  21. ncbi Ni(II) activates the Nrf2 signaling pathway in human monocytic cells
    Jill B Lewis
    Department of Oral Biology and Maxillofacial Pathology, AD1417, Medical College of Georgia, Augusta, GA 30912-1126, USA
    Biomaterials 27:5348-56. 2006
    b>Nickel is a component of biomedical alloys that is released during corrosion and causes inflammation in tissues by as yet unknown mechanisms...
  22. ncbi Dietary chromium and nickel enhance UV-carcinogenesis in skin of hairless mice
    Ahmed N Uddin
    Nelson Institute of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, Tuxedo, NY 10987, USA
    Toxicol Appl Pharmacol 221:329-38. 2007
    The skin cancer enhancing effect of chromium (in male mice) and nickel in UVR-irradiated female Skh1 mice was investigated. The dietary vitamin E and selenomethionine were tested for prevention of chromium-enhanced skin carcinogenesis...
  23. ncbi T cell receptor (TCR) interaction with haptens: metal ions as non-classical haptens
    Hermann-Josef Thierse
    , , D-79108 Freiburg, Germany
    Toxicology 209:101-7. 2005
    ..However, the most common contact sensitizer in the industrialized world is nickel. In contrast to classical haptens, nickel ions do not form covalent bonds to proteins, but rather become caught in ..
  24. ncbi Requirement of hydD, hydE, hypC and hypE genes for hydrogenase activity in Helicobacter pylori
    Stephane Benoit
    Department of Microbiology, 812 Biological Sciences Building, University of Georgia, Athens, GA 30602, USA
    Microb Pathog 36:153-7. 2004
    Helicobacter pylori possesses a membrane-bound, nickel containing, hydrogen uptake hydrogenase enzyme; its synthesis requires structural as well as accessory proteins, the latter needed for the complete maturation of the enzyme...
  25. ncbi NreB from Achromobacter xylosoxidans 31A Is a nickel-induced transporter conferring nickel resistance
    G Grass
    Department of Soil, Water, and Environmental Science, University of Arizona, Tucson 85721, USA
    J Bacteriol 183:2803-7. 2001
    There are two distinct nickel resistance loci on plasmid pTOM9 from Achromobacter xylosoxidans 31A, ncc and nre. Expression of the nreB gene was specifically induced by nickel and conferred nickel resistance on both A...
  26. ncbi The K3 rotary nickel-titanium file system
    Richard E Mounce
    Private Practice, 511 Southwest 10th Avenue, No 1108, Portland, OR 97205, USA
    Dent Clin North Am 48:137-57. 2004
    The K3 rotary nickel-titanium file system by SybronEndo is a state-of-the-art rotary nickel-titanium endodontic instrumentation method combines excellent cutting characteristics with a robust sense of tactile control and excellent ..
  27. ncbi Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel
    Theodore A Slotkin
    Department of Pharmacology and Cancer Biology Box 3813, Duke University Medical Center, Durham, NC 27710, USA
    Toxicol Appl Pharmacol 233:211-9. 2008
    ....
  28. ncbi Inhibition of Na/Ca exchange by external Ni in guinea-pig ventricular myocytes at 37 degrees C, dialysed internally with cAMP-free and cAMP-containing solutions
    A K Hinde
    Cardiovascular Research Laboratories, School of Medical Sciences, University of Bristol, UK
    Cell Calcium 25:321-31. 1999
    ..External Nickel (Ni) ions are used widely to inhibit the exchange but little is known about the mode of Ni action...
  29. ncbi Wear of nickel-titanium endodontic instruments evaluated by scanning electron microscopy: effect of ion implantation
    E Rapisarda
    Dental School, University of Catania, Italy
    J Endod 27:588-92. 2001
    The present work analyzes possible increases in resistance to wear of nickel-titanium endodontic instruments that have undergone a process of ionic implantation. ProFile ...
  30. ncbi Lung cancer mortality in UK nickel-cadmium battery workers, 1947-2000
    T Sorahan
    Institute of Occupational Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Occup Environ Med 61:108-16. 2004
    To investigate mortality from lung cancer in nickel-cadmium battery workers in relation to cumulative exposure to cadmium hydroxide.
  31. ncbi Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells
    Theodore A Slotkin
    Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA
    Brain Res 1263:23-32. 2009
    ..These results further show how combined use of cell cultures and microarray technology can guide future in vivo work on diverse developmental neurotoxicants...
  32. ncbi Constitutively high expression of the histidine biosynthetic pathway contributes to nickel tolerance in hyperaccumulator plants
    Robert A Ingle
    Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, United Kingdom
    Plant Cell 17:2089-106. 2005
    ..These results suggest that ATP-PRT expression plays a major role in regulating the pool of free His and contributes to the exceptional Ni tolerance of hyperaccumulator Alyssum species...
  33. ncbi Soluble nickel inhibits HIF-prolyl-hydroxylases creating persistent hypoxic signaling in A549 cells
    Todd L Davidson
    Nelson Institute of Environmental Medicine, New York University, School of Medicine, Tuxedo, New York 10987, USA
    Mol Carcinog 45:479-89. 2006
    Soluble nickel compounds are carcinogenic to humans although the mechanism by which they cause cancer remains unclear...
  34. ncbi Nickel allergy in mice: enhanced sensitization capacity of nickel at higher oxidation states
    S Artik
    Division of Immunology, Medical Institute of Environmental Hygiene and Dermatology Clinic, Heinrich Heine University, Dusseldorf, Germany
    J Immunol 163:1143-52. 1999
    Attempts to induce contact hypersensitivity to nickel in mice using, e.g., Ni(II)Cl2 often failed...
  35. ncbi Relationships of nicotianamine and other amino acids with nickel, zinc and iron in Thlaspi hyperaccumulators
    Damien L Callahan
    School of Chemistry, The University of Melbourne, Parkville, VIC 3010, Australia
    New Phytol 176:836-48. 2007
    ..Closely-related nickel (Ni)- and zinc (Zn)-hyperaccumulating species were studied to determine whether a correlation exists between the ..
  36. ncbi Molecular mechanisms of nickel carcinogenesis: gene silencing by nickel delivery to the nucleus and gene activation/inactivation by nickel-induced cell signaling
    Max Costa
    Department of Environmental Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Environ Monit 5:222-3. 2003
    We have summarized the molecular and cellular events involved in nickel (Ni) compound induced carcinogenesis...
  37. ncbi Toxic response of nickel nanoparticles in human lung epithelial A549 cells
    Maqusood Ahamed
    King Abdullah Institute for Nanotechnology, King Saud University, P O Box 2454, Riyadh 11451, Saudi Arabia
    Toxicol In Vitro 25:930-6. 2011
    b>Nickel nanoparticle (Ni NP) is increasingly used in modern industries such as catalysts, sensors and electronic applications. Due to wide-spread industrial applications the inhalation is the primary source of exposure to Ni NPs...
  38. ncbi Oxidized NiTi surfaces enhance differentiation of osteoblast-like cells
    A Michiardi
    Centre of Reference for Bioengineering of Catalonia, Biomaterials and Biomechanics Division, Department of Materials Science and Metallurgy, Technical University of Catalonia UPC, Avda Diagonal 647, Barcelona, 08028, Spain
    J Biomed Mater Res A 85:108-14. 2008
    ..The improvement of osteoblast differentiation due to OT treatment could accelerate bone formation, and, therefore, could allow earlier loading of NiTi devices used in dental and orthopedic applications...
  39. ncbi Occupational toxicology of nickel and nickel compounds
    Jinshun Zhao
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    J Environ Pathol Toxicol Oncol 28:177-208. 2009
    b>Nickel and nickel compounds are widely used in industry. The high consumption of nickel products inevitably leads to occupational and environmental pollution...
  40. ncbi Docking studies of Nickel-Peptide deformylase (PDF) inhibitors: exploring the new binding pockets
    Qiang Wang
    Institute of Theoretical Chemistry, Shandong University, Jinan 250100, China
    Biophys Chem 122:43-9. 2006
    ..Moreover, a new binding pocket is also explored. All these may provide something useful for designing the potent inhibitors...
  41. ncbi Roles of His-rich hpn and hpn-like proteins in Helicobacter pylori nickel physiology
    Susmitha Seshadri
    Department of Microbiology, University of Georgia, Athens, GA 30602, USA
    J Bacteriol 189:4120-6. 2007
    ..gene-targeted hpn and hpn-like mutants and a mutant with mutations in both hpn genes were more sensitive to nickel, cobalt, and cadmium toxicity than was the parent strain, with the hpn-like strain showing the most metal ..
  42. ncbi Nickel release behavior, cytocompatibility, and superelasticity of oxidized porous single-phase NiTi
    Shuilin Wu
    Department of Physics and Materials Science, City University of Hong Kong, Kowloon, Hong Kong
    J Biomed Mater Res A 81:948-55. 2007
    ..and larger area of porous NiTi compared to dense NiTi make it more vulnerable from the viewpoint of release of nickel, which can cause deleterious effects in the human body...
  43. ncbi Promising in vitro performances of a new nickel-free stainless steel
    Lucio Montanaro
    Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Bologna, Italy
    J Mater Sci Mater Med 17:267-75. 2006
    ..However, the presence in its composition of a high quantity of nickel, an agent known to trigger toxic and allergic responses, is cause for concern...
  44. ncbi Flame atomic absorption spectrometric determination of zinc, nickel, iron and lead in different matrixes after solid phase extraction on sodium dodecyl sulfate (SDS)-coated alumina as their bis (2-hydroxyacetophenone)-1, 3-propanediimine chelates
    M Ghaedi
    Chemistry Department, Yasouj University, Yasouj 75914 353, Iran
    J Hazard Mater 166:1441-8. 2009
    ..The method is based on the adsorption of zinc, nickel, iron and lead on sodium dodecyl sulfate (SDS)-coated alumina, which is also chelated with bis (2-..
  45. ncbi Nickel-binding and accessory proteins facilitating Ni-enzyme maturation in Helicobacter pylori
    Robert J Maier
    Department of Microbiology, University of Georgia, Athens, GA 30602, USA
    Biometals 20:655-64. 2007
    ..The bacterium colonizes over one-half of the worlds population. Nickel plays a major role in the bacteriums colonization and persistence attributes as two nickel enzyme sinks obligately ..
  46. ncbi Characteristics of a nickel-albumin binding assay for assessment of myocardial ischaemia
    Sandra Huber da Silva
    Programa de Pós Graduação em Ciências Farmacêuticas, Centro de Ciencias da Saude, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
    Biomarkers 15:353-7. 2010
    The aim of this study was to describe a method to measure ischaemia-induced alterations of the binding capacity of serum albumin to exogenous nickel.
  47. ncbi Direct observation of triple ions in aqueous solutions of nickel(II) sulfate: a molecular link between the gas phase and bulk behavior
    Detlef Schröder
    Institute of Organic Chemistry and Biochemistry, vvi, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    J Am Chem Soc 133:2444-51. 2011
    Electrospray ionization of an aqueous solution of nickel(II) sulfate provides direct experimental evidence for the formation of triple ions of the type [Ni(2)(SO(4))(H(2)O)(n)](2+) and [Ni(SO(4))(2)](2-), whose existence in aqueous ..
  48. ncbi Nickel deficiency gives rise to the defective hydrogenase phenotype of hydC and fnr mutants in Escherichia coli
    L F Wu
    Laboratoire de Microbiologie, CNRS, INSA, Villeurbanne, France
    Mol Microbiol 3:1709-18. 1989
    ..activity and other hydrogenase-related functions can be restored to hydC mutants by the specific addition of nickel salts to the growth medium...
  49. ncbi Influence of deep dry cryogenic treatment on cutting efficiency and wear resistance of nickel-titanium rotary endodontic instruments
    Thilla Sekar Vinothkumar
    Department of Conservative Dentistry and Endodontics, Meenakshi Ammal Dental College, Chennai, Tamilnadu, India
    J Endod 33:1355-8. 2007
    This study tested the effect of cryogenic treatment on nickel-titanium (NiTi) endodontic instruments. Ten rotary NiTi instruments (ProFile 30, 0...
  50. ncbi Sequence-specific binding of DNA and RNA to immobilized Nickel ions
    Branislav Nastasijevic
    Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Biochem Biophys Res Commun 366:420-5. 2008
    Immobilization of divalent Nickel cations provides a tool for affinity purification of proteins containing hexahistidine tags...
  51. ncbi 24-Epibrassinolide protects against the stress generated by salinity and nickel in Brassica juncea
    B Ali
    Plant Physiology Section, Department of Botany, Aligarh Muslim University, Aligarh, India
    Chemosphere 72:1387-92. 2008
    ..The antioxidative enzymes and the level of proline exhibited a significant increase in response to EBL as well as to NaCl and/or NiCl2 stress...
  52. ncbi Binding of Ni2+ to a histidine- and glutamine-rich protein, Hpn-like
    Yi Bo Zeng
    Department of Chemistry and Open Laboratory of Chemical Biology, The University of Hong Kong, Pokfulam Road, Hong Kong, People s Republic of China
    J Biol Inorg Chem 13:1121-31. 2008
    ..by the hpnl gene in Helicobacter pylori and featuring a histidine-rich and two glutamine-rich motifs, can render nickel tolerance to H. pylori when the external nickel level reaches toxic limits...
  53. ncbi Surface mechanical properties, corrosion resistance, and cytocompatibility of nitrogen plasma-implanted nickel-titanium alloys: a comparative study with commonly used medical grade materials
    K W K Yeung
    Division of Spine Surgery, Department of Orthopaedics and Traumatology, Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong
    J Biomed Mater Res A 82:403-14. 2007
    Stainless steel and titanium alloys are the most common metallic orthopedic materials. Recently, nickel-titanium (NiTi) shape memory alloys have attracted much attention due to their shape memory effect and super-elasticity...
  54. ncbi Arsenic limits trace mineral nutrition (selenium, zinc, and nickel) in Bangladesh rice grain
    Paul N Williams
    Research Centre for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China
    Environ Sci Technol 43:8430-6. 2009
    ..Grain concentration characteristics for selenium (Se), zinc (Zn), and nickel (Ni), however, were markedly different...
  55. ncbi Ni(II) and Co(II) sensing by Escherichia coli RcnR
    Jeffrey S Iwig
    Washington University School of Medicine, Department of Biochemistry and Molecular Biophysics, Saint Louis, Missouri 63110, USA
    J Am Chem Soc 130:7592-606. 2008
    ..coli, to provide a better understanding how different nickel levels are sensed in E. coli...
  56. ncbi Crystal structure of HypA, a nickel-binding metallochaperone for [NiFe] hydrogenase maturation
    Satoshi Watanabe
    Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, Japan
    J Mol Biol 394:448-59. 2009
    ..In addition, the hexameric structure of HypA is formed in the crystal packing. Several hydrogen bonds and hydrophobic interactions stabilize the hexamer interface. These findings suggest the functional diversity of HypA proteins...
  57. ncbi Extrusion of debris after use of rotary nickel-titanium files with different pitch: a pilot study
    Elham A Elmsallati
    Pulp Biology and Endodontics, Department of Restorative Sciences, Tokyo Medical and Dental University, Tokyo, Japan
    Aust Endod J 35:65-9. 2009
    ..was to quantitatively compare the amount of debris extruded apically from curved canals when using rotary nickel-titanium files with different pitches and sequences of use under the same preparation technique...
  58. ncbi Structural and mechanistic insights into Helicobacter pylori NikR activation
    C Bahlawane
    CNRS UMR 5249 Laboratoire de Chimie et Biologie des Métaux, France
    Nucleic Acids Res 38:3106-18. 2010
    ..shows that HpNikR adopts a defined conformation in solution, resembling the cis-conformation and suggests that nickel does not trigger large conformational changes in HpNikR...
  59. ncbi Corrosion resistance, surface mechanical properties, and cytocompatibility of plasma immersion ion implantation-treated nickel-titanium shape memory alloys
    K W K Yeung
    Division of Spine Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Faculty of Medicine, The University of Hong Kong, 5/F Professorial Block, Pokfulam, Hong Kong
    J Biomed Mater Res A 75:256-67. 2005
    b>Nickel-titanium shape memory alloys are promising materials in orthopedic applications because of their unique properties...
  60. ncbi The contact allergen nickel sensitizes primary human endothelial cells and keratinocytes to TRAIL-mediated apoptosis
    Marc Schmidt
    Department of Dermatology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany
    J Cell Mol Med 14:1760-76. 2010
    ..Here, we demonstrate that certain environmental conditions, such as exposure to the widespread allergen nickel, can dramatically increase the susceptibility of naturally resistant primary endothelial cells or keratinocytes to ..
  61. ncbi Investigation of nickel suppression and cytocompatibility of surface-treated nickel-titanium shape memory alloys by using plasma immersion ion implantation
    K W K Yeung
    Department of Orthopaedics and Traumatology, Division of Spine Surgery, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    J Biomed Mater Res A 72:238-45. 2005
    b>Nickel-titanium (NiTi) shape memory alloys are increasingly being used in orthopedic applications. However, there is a concern that Ni is harmful to the human body...
  62. ncbi Assessing the biocompatibility of NiTi shape memory alloys used for medical applications
    Mohammed Es-Souni
    Institute for Materials and Surface Technology, University of Applied Sciences of Kiel, 24149, Kiel, Germany
    Anal Bioanal Chem 381:557-67. 2005
    ..Smooth surfaces with well-controlled structures and chemistries of the outermost protective TiO2 layer lead to negligible release of Ni ions, with concentrations below the normal human daily intake...
  63. ncbi An in vitro comparison of Profile GT and GTX nickel-titanium rotary instruments in apical transportation and length control in mandibular molar
    Mian K Iqbal
    Postgraduate Program in Endodontics, Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19103, USA
    J Endod 36:302-4. 2010
    Profile GT files have been redesigned and are now marketed as GTX nickel-titanium rotary files.
  64. ncbi Rotary nickel-titanium GT and ProTaper files for root canal shaping by novice operators: a radiographic and micro-computed tomography evaluation
    Diana Gekelman
    Division of Endodontics, Department of Preventive and Restorative Dental Sciences, University of California School of Dentistry, San Francisco, California 94143 0758, USA
    J Endod 35:1584-8. 2009
    ..The purpose of this study was to assess canal preparation outcomes in vitro by novice clinicians after standardized teaching sessions...
  65. ncbi Differential effect of equal copper, cadmium and nickel concentration on biochemical reactions in wheat seedlings
    Ewa Gajewska
    Department of Plant Physiology and Biochemistry, University of Łódź, Banacha 12 16, 90 237 Łódź, Poland
    Ecotoxicol Environ Saf 73:996-1003. 2010
    Influence of 75 microM copper (Cu), cadmium (Cd) and nickel (Ni) on growth, tissue metal accumulation, non-protein thiols (NPT) and glutathione (GSH) contents, membrane damage, lipid peroxidation and protein oxidation as well as protease, ..
  66. ncbi Trace metal enrichments in core sediments in Muthupet mangroves, SE coast of India: application of acid leachable technique
    D Janaki Raman
    Department of Geology, School of Earth and Atmospheric Sciences, University of Madras, Guindy Campus, Chennai 600 025, India
    Environ Pollut 145:245-57. 2007
    ..Comparison of acid leachable trace metals indicates increase in concentrations in the study area and the sediments act as a sink for trace metals contributed from multiple sources...
  67. ncbi In vitro release of elements from prosthodontic base metal alloys: effect of protein-containing biologic environments
    Neslihan Efeoglu
    Department of Restorative Dentistry, Leeds Dental Institute, University of Leeds, United Kingdom
    Int J Prosthodont 19:250-2. 2006
    This study aimed to investigate the release of nickel, copper, zinc, cadmium, magnesium, and lead from prosthodontic base metal alloys into protein-containing biologic solutions.
  68. ncbi Comparative study of torsional and bending properties for six models of nickel-titanium root canal instruments with different cross-sections
    Xuejun Xu
    State Key Laboratory for Turbulence and Complex System and Department of Mechanics and Engineering Science, Peking University, Beijing, China
    J Endod 32:372-5. 2006
    This study investigated the influence of cross-section profile on the mechanical behaviors of six commercial nickel-titanium (NiTi) root canal instruments using the finite element method...
  69. ncbi [The electrochemical behavior of titanium and dental casting in modelling oral conditions]
    István Pelsoczi-Kovács
    Szegedi Tudományegyetem Altalános Orvostudományi Kar, Fogászati es Szájsebészeti Klinika
    Fogorv Sz 98:251-5. 2005
    ..b>Nickel-chromium, cobalt-chromium, high palladium content and gold alloys as well as CP grade I titanium cast samples ..
  70. ncbi Heavy metal and Pb isotopic compositions of aquatic organisms in the Pearl River Estuary, South China
    C C M Ip
    Department of Civil and Structural Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
    Environ Pollut 138:494-504. 2005
    ..The results of Pb isotopic compositions indicated that the bioaccumulation of Pb in fish come from a wide variety of food sources and/or exposure pathways, particularly the anthropogenic inputs...
  71. ncbi The influence of body size, condition index and tidal exposure on the variability in metal bioaccumulation in Mytilus edulis
    Valentine K Mubiana
    Laboratory of Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Pollut 144:272-9. 2006
    ..The study recommends stringent measures during sampling for biomonitoring or metal concentrations at each location must be normalized to a common body size, CI and tidal height...
  72. ncbi Combinatorial search of thermoelastic shape-memory alloys with extremely small hysteresis width
    Jun Cui
    Materials Analysis and Chemical Science, GE Global Research Center, Niskayuan, New York 12309, USA
    Nat Mater 5:286-90. 2006
    ..We have also identified a new composition region of titanium-rich SMAs with potential for improved control of SMA properties...
  73. ncbi Effect of fluoride prophylactic agents on the mechanical properties of nickel-titanium-based orthodontic wires
    Mary P Walker
    Departments of Restorative Dentistry and Oral Biology, School of Dentistry, University of Missouri Kansas City, 650 E 25th Street, Kansas City, MO 64108 2784
    Am J Orthod Dentofacial Orthop 127:662-9. 2005
    ..The purpose of this investigation was to study the effects of fluoride prophylactic agents on the mechanical properties of nickel-titanium (Ni-Ti) and copper-nickel-titanium (Cu-Ni-Ti) orthodontic archwires.
  74. ncbi Effect of three nickel-titanium rotary file techniques on infected root dentin reduction
    Marie-Pierre Chuste-Guillot
    Department of Endodontics, Faculty of Odontology, , Bordeaux, France
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:254-8. 2006
    OBJECTIVE: This study compared the bacterial reduction of in vitro infected root canals after instrumentation by 3 nickel-titanium (NiTi) rotary files with different taper and diameter versus manual stainless steel files...
  75. ncbi Effectiveness of a hand file and three nickel-titanium rotary instruments for removing gutta-percha in curved root canals during retreatment
    Jorg F Schirrmeister
    Department of Operative Dentistry and Periodontology, Albert Ludwigs University of Freiburg, Freiburg, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:542-7. 2006
    ..This study intended to compare the effectiveness of hand files and FlexMaster, ProTaper, and RaCe rotary instruments for removing gutta-percha in curved root canals during retreatment...
  76. ncbi Influence of instrument taper on the resistance to fracture of endodontically treated roots
    Tannaz Zandbiglari
    Department of Operative Dentistry, , , Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:126-31. 2006
    ..05). CONCLUSIONS: The roots were significantly weakened by the preparation with greater taper instruments. An obturation with AH Plus did not increase the fracture resistance...
  77. ncbi Influence of simulated clinical use on the torsional behavior of nickel-titanium rotary endodontic instruments
    Maria Guiomar Azevedo Bahia
    Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:675-80. 2006
    ..The aim of this study was to assess the influence of cyclic deformation up to one half and three quarters of the fatigue life of NiTi rotary endodontic instruments on their behavior in torsion...
  78. ncbi Influence of sodium hypochlorite on fracture properties and corrosion of ProTaper Rotary instruments
    E Berutti
    Department of Endodontics, School of Dentistry, University of Turin, Turin, Italy
    Int Endod J 39:693-9. 2006
    ..The NiTi alloy may acts as the anode and thus undergoes corrosion...
  79. ncbi Trend in metals variation in Tasik Chini, Pahang, Peninsular Malaysia
    M Shuhaimi-Othman
    School of Environmental and Natural Resource Sciences, Faculty of Science and Technology, National University of Malaysia UKM, Bangi, 43600 Selangor, Malaysia
    Environ Monit Assess 143:345-54. 2008
    ..including iron (Fe), aluminum (Al), manganese (Mn), barium (Ba), zinc (Zn), lead (Pb), copper (Cu), cadmium (Cd), nickel (Ni), chromium (Cr) and cobalt (Co)...
  80. ncbi Cytotoxicity of metal ions to human oligodendroglial cells and human gingival fibroblasts assessed by mitochondrial dehydrogenase activity
    Y Issa
    Biomaterials Research Group, School of Dentistry, University of Manchester, UK
    Dent Mater 24:281-7. 2008
    ..To assess the variable concentrations of several metal salts on human oligodendrocyte MO3.13 and human gingival fibroblasts HGF and to enable any difference in cell type sensitivity to be examined...
  81. ncbi Effect of environment on low-cycle fatigue of a nickel-titanium instrument
    Gary S P Cheung
    Area of Endodontics, Faculty of Dentistry, University of Hong Kong, Hong Kong SAR, China
    J Endod 33:1433-7. 2007
    This study examined the low-cycle fatigue (LCF) behavior of a nickel-titanium (NiTi) engine-file under various environmental conditions...
  82. ncbi [Advantages and limits of nickel-titanium instruments for root canal preparation. A review of the current literature]
    Silvio Taschieri
    Division d'Odontologie, , , Milan, Italie
    Schweiz Monatsschr Zahnmed 115:1000-5. 2005
    In recent years, an important innovation in the field of dentistry has been the introduction of nickel-titanium alloy instruments...
  83. ncbi The electrochemical behavior and surface analysis of Ti49.6Ni45.1Cu5Cr0.3 alloy for orthodontic usage
    Y F Zheng
    Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China
    J Biomed Mater Res B Appl Biomater 86:335-40. 2008
    ..Besides Ni, a Cu enriched sub-layer was also found. The nickel ion release rate showed a typical time-related decrease as examined by ICP/OES...
  84. ncbi The Eulerian buckling test for orthodontic wires
    R De Santis
    IMCB CNR Institute of Composite and Biomedical Materials, National Research Council, Naples, Italy
    Eur J Orthod 30:190-8. 2008
    ..Elastic titanium molybdenum alloy (TMA; SDS Ormco) and superelastic Nitinol (3M Unitek) and copper nickel-titanium (NiTi; SDS Ormco) wires, each having a rectangular cross section of 0.016 x 0.022 square inches (0.41 x 0...
  85. ncbi Effect of fluoride released from fluoride-containing dental restoratives on NiTi orthodontic wires
    Yong Hoon Kwon
    Department of Dental Materials, College of Dentistry and Medical Research Institute, Pusan National University, Busan 602 739, Korea
    Dent Mater J 27:133-8. 2008
    ..Therefore, despite the released fluoride, wires in contact with the fluoride-containing restoratives were not damaged regardless of the pH value of test solution...
  86. ncbi Mechanical properties of a new and improved nickel-titanium alloy for endodontic use: an evaluation of file flexibility
    Gianluca Gambarini
    Department of Dental Science, Sapienza University of Rome, Rome, Italy
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:798-800. 2008
    ..The purpose of the study was to determine whether this new manufacturing method produces NiTi instruments (TF) of superior flexibility...
  87. ncbi Magnetic susceptibility and electrical conductivity of metallic dental materials and their impact on MR imaging artifacts
    Jana Starcuková
    Institute of Scientific Instruments of the ASCR, v v i, Academy of Sciences of the Czech Republic, Kralovopolska 147, 612 64 Brno, Czech Republic
    Dent Mater 24:715-23. 2008
    ....
  88. ncbi Corrosion behavior of shape memory, superelastic, and nonsuperelastic nickel-titanium-based orthodontic wires at various temperatures
    Deo K Pun
    Dental Biomaterials, School of Dentistry, Marquette University, Milwaukee, WI 53201, USA
    Dent Mater 24:221-7. 2008
    b>Nickel-titanium orthodontic wires have various temperature-dependent phases. The purpose of this study was to investigate temperature-dependent corrosion characteristics of shape memory, superelastic, and nonsuperelastic orthodontic wires.
  89. ncbi Microstructural studies of 35 degrees C copper Ni-Ti orthodontic wire and TEM confirmation of low-temperature martensite transformation
    William A Brantley
    Section of Restorative and Prosthetic Dentistry, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
    Dent Mater 24:204-10. 2008
    Previous temperature-modulated differential scanning calorimetry (TMDSC) study of nickel-titanium orthodontic wires revealed a large exothermic low-temperature peak that was attributed to transformation within martensitic NiTi.
  90. ncbi Cyclic fatigue of different nickel-titanium endodontic rotary instruments
    Teresa Roberta Tripi
    Faculty of Dentistry, University of Catania, Catania, Italy
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:e106-14. 2006
    OBJECTIVE: A comparative study of the fatigue resistance of rotary nickel-titanium endodontic instruments was performed with the aim of assessing the influence of both instrument design and surface treatment on flexural fracture...
  91. ncbi The effect of sodium hypochlorite on the surface characteristics and fatigue resistance of ProFile nickel-titanium instruments
    Renata de Castro Martins
    Department of Metallurgical and Materials Engineering, Engineering School, Federal University of Minas Gerais, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:e99-105. 2006
    ..CONCLUSIONS: Immersion of ProFile in 5.25% NaOCl for 24 hours had no influence on surface characteristics and fatigue resistance. Simulated clinical use was a decisive factor in the decrease of fatigue life...
  92. ncbi Influence of a brushing working motion on the fatigue life of NiTi rotary instruments
    G Plotino
    Department of Endodontics, Catholic University of Sacred Heart, Rome, Italy
    Int Endod J 40:45-51. 2007
    ..To evaluate the cyclic fatigue resistance of Mtwo NiTi rotary instruments when used with a brushing or no-brushing action in oval root canals...
  93. ncbi Optimizing the molarity of a EDTA washing solution for saturated-soil remediation of trace metal contaminated soils
    M D Andrade
    Department of Bioresource Engineering, McGill University, Macdonald Campus, Ste Anne de Bellevue, Quebec, Canada
    Environ Pollut 147:781-90. 2007
    ..For equal amounts of EDTA, concentrating the washing solution and applying it and the ensuing rinses in a smaller 1:5 L:S weight ratio, instead of a 2:5 L:S weight ratio, increased the extraction of targeted Cr, Cu, Ni, Pb and Zn...
  94. ncbi Evidence of excessive releases of metals from primitive e-waste processing in Guiyu, China
    Coby S C Wong
    Department of Earth Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong
    Environ Pollut 148:62-72. 2007
    ..In summary, it was evident that the riverine environment of Guiyu was heavily impacted by e-waste related activities...
  95. ncbi Trace metal concentration in Great Tit (Parus major) and Greenfinch (Carduelis sinica) at the Western Mountains of Beijing, China
    Haili Deng
    Ministry of Education Key Laboratory for Biodiversity Sciences and Ecological Engineering, College of Life Sciences, Beijing Normal University, Beijing 100875, China
    Environ Pollut 148:620-6. 2007
    ..Gender related variations were body part and species specific. Meta-analyses using data from this study and other studies suggested that metal concentrations of Great Tits at our study site were relatively low and below the toxic levels...
  96. ncbi A dozen ways to prevent nickel-titanium rotary instrument fracture
    Peter M Di Fiore
    Predoctoral Endodontics, New York University, College of Dentistry, Department of Endodontics, New York, NY 10010, USA
    J Am Dent Assoc 138:196-201; quiz 249. 2007
    and Overview. With the increased use of nickel-titanium (NiTi) rotary instruments for root canal preparation in endodontics, instrument fracture has become more prevalent...
  97. ncbi Prevalence and management of instrument fracture in the postgraduate endodontic program at the Dental School of Athens: a five-year retrospective clinical study
    Giorgos N Tzanetakis
    Department of Endodontics, Dental School, University of Athens, Athens, Greece
    J Endod 34:675-8. 2008
    ..41%. The prevalence of stainless steel hand and rotary nickel-titanium instrument fracture by postgraduate students were 0.55% and 1.33%, respectively...
  98. ncbi Thermal analysis of as-received and clinically retrieved copper-nickel-titanium orthodontic archwires
    Matthew C Biermann
    Department of Developmental Sciences, Marquette University, Milwaukee, WI 53201 1881, USA
    Angle Orthod 77:499-503. 2007
    To compare as-received copper-nickel-titanium (CuNiTi) archwires to those used in patients by means of differential scanning calorimetry (DSC)...
  99. ncbi Three-dimensional analysis of cutting behavior of nickel-titanium rotary instruments by microcomputed tomography
    Ya Shen
    Department of Oral Biological and Medical Sciences, Division of Endodontics, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    J Endod 34:606-10. 2008
    The cutting behavior of nickel-titanium rotary instruments with and without irrigation was evaluated in a bovine bone model. Six brands of NiTi rotary instruments were constrained into a curved trench...
  100. ncbi Metallic dental material biocompatibility in osteoblastlike cells: correlation with metal ion release
    María C Cortizo
    Catedra de Bioquimica Patologica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, 47 y 115 1900 La Plata, Argentina
    Biol Trace Elem Res 100:151-68. 2004
    ..The dissolution of the metallic materials was dependent on the composition of the simulated biological media...
  101. ncbi Factors influencing the fracture of nickel-titanium rotary instruments
    B Martin
    Division of Dental Pathology and Therapeutics, Department of Stomatology, School of Dentistry, University of Santiago de Compostela, Spain
    Int Endod J 36:262-6. 2003
    To evaluate the effect of rotational speed and the angle and radius of curvature of root canals on the fracture of two types of nickel-titanium rotary instruments: K3 and ProTaper.

Research Grants82

  1. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2007
    ..b>Nickel ions are now recognized as a critical cofactor required for catalytic activity of urease and are necessary for ..
  2. Ultraprecision Diamond Machining of Conventional Non-Diamond Machinable Materials
    Gang Zhang; Fiscal Year: 2007
    ..It cannot machine many important materials such as ferrous alloys, stainless steel, titanium and nickel due to catastrophic diamond tool wear...
  3. BIOLOGICALLY RELATED IRON-SULFUR CHEMISTRY
    RICHARD HADLEY HOLM; Fiscal Year: 2010
    ..understanding of biologically relevant cluster clusters containing iron, sulfur, and molybdenum, vanadium, or nickel, various types of which are found at all levels of life...
  4. T CELLS IN LUNG INFLAMMATION
    Peter Kao; Fiscal Year: 2000
    ..Histidine-tagged proteins in nuclear extracts are affinity-purified on nickel chelate affinity columns...
  5. Vaccinia Proteome Affinity Reagents From Phage Display
    Philip Felgner; Fiscal Year: 2005
    ..The individual proteins will be coated onto separate wells of either nickel, or anti-HA coated 96-well plates, and the plates will be used to scan the phage display libraries for high ..
  6. IN VITRO INVESTIGATION OF SLIDING MECHANICS
    Robert Kusy; Fiscal Year: 2002
    ..materials (titanium brackets and composite archwires) and conventional orthodontic materials (stainless steel, nickel-titanium, beta-titanium, polycrystalline alumina, and single crystal sapphire) will be measured...
  7. UREASE AND GENE EXPRESSION OF HELICOBACTER PYLORI
    HARRY MOBLEY; Fiscal Year: 2003
    ..A rough topological model for the insertion of NixA, the high affinity nickel transport protein, into the cytoplasmic membrane has been established and we have identified 12 amino acid ..
  8. FUNCTIONAL ANALYSIS OF A LEAD/CADMIUM/ZINC ATPASE
    Bharati Mitra; Fiscal Year: 2007
    ..These pumps maintain homeostasis of essential trace metals like copper, zinc, cobalt and nickel, and mediate resistance to toxic metals such as lead, cadmium and silver...
  9. Carcinogenesis of Nickel and Epigenetic Control
    Max Costa; Fiscal Year: 2010
    ..The affinity constant of nickel ions binding to this JmjC facial triad is predicted to be at least 3 orders of magnitude greater than that of Fe...
  10. Carcinogenesis of Nickel and Epigenetic Control
    Max Costa; Fiscal Year: 2007
    ..The affinity constant of nickel ions binding to this JmjC facial triad is predicted to be at least 3 orders of magnitude greater than that of Fe...
  11. X-RAY ABSORPTION SPECTROSCOPY OF METALLOENZYMES
    Robert Scott; Fiscal Year: 1993
    ..Examples of all known types of nickel-containing enzymes, including jackbean urease, Klebsiella aerogenes urease, Desulfovibrio gigas (NiFe) hydrogenase,..
  12. DNA Damage and Tobacco-Induced Lung Cancer
    ERIC MOON SHONG TANG; Fiscal Year: 2007
    ..We recently found that nickel, chromium, and lipid peroxidation metabolites can greatly reduce cellular DNA repair capacity...
  13. DNA Damage and Tobacco-Induced Lung Cancer
    ERIC MOON SHONG TANG; Fiscal Year: 2009
    ..We recently found that nickel, chromium, and lipid peroxidation metabolites can greatly reduce cellular DNA repair capacity...
  14. FUNCTIONAL ANALYSIS OF A LEAD/CADMIUM/ZINC ATPASE
    Bharati Mitra; Fiscal Year: 2010
    ..These pumps maintain homeostasis of essential trace metals like copper, zinc, cobalt and nickel, and mediate resistance to toxic metals such as lead, cadmium and silver...
  15. Nickel Metabolism in Helicobacter pylori
    Robert Maier; Fiscal Year: 2006
    ..Two nickel-containing enzymes, urease and hydrogenase, are important for the bacterium's mucosal-colonizing abilities...
  16. CARCINOGENESIS OF ENVIRONMENTALLY RELEVANT NI COMPOUNDS
    Max Costa; Fiscal Year: 2005
    In the past several years we have demonstrated that carcinogenic nickel compounds inactivate g ne expression by enhancing DNA methylation and inhibiting histone acetylation...
  17. REGULATORY MECHANISMS IN THE IMMUNE SYSTEM
    John Kappler; Fiscal Year: 2007
    T cell mediated metal hypersensitivity is wide spread in the human population. Two examples are hypersensitivity to nickel (Ni) often associated with exposure to Ni contained jewelry and to beryllium (Be) a common problem in the ..
  18. BIOINORGANIC CHEMISTRY OF CARBON MONOXIDE DEHYDROGENASE
    PAUL LINDAHL; Fiscal Year: 2009
    ..This oxygen-sensitive bifunctional enzyme contains two nickel-iron-sulfur cluster active-sites which are unique in biology...
  19. Long Term Cardiovascular Effects of Inhaled Nanoparticles
    Lung Chi Chen; Fiscal Year: 2007
    ..Three different nanoparticles will be used to test the hypothesis, nickel, titanium, and carbon...