cadmium

Summary

Summary: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.

Top Publications

  1. ncbi Current status of cadmium as an environmental health problem
    Lars Jarup
    Department of Epidemiology and Public Health, Imperial College London, London, UK
    Toxicol Appl Pharmacol 238:201-8. 2009
  2. ncbi Molecular mechanisms of metal hyperaccumulation in plants
    Nathalie Verbruggen
    Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    New Phytol 181:759-76. 2009
  3. ncbi Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells
    Gaofeng Jiang
    Faculty of Preventive Medicine, Medical College, Wuhan University of Science and Technology, Huangjiahu Campus, Wuhan 430065, Hubei Province, People s Republic of China
    Toxicology 244:49-55. 2008
  4. ncbi Expression of arabidopsis CAX2 in tobacco. Altered metal accumulation and increased manganese tolerance
    K D Hirschi
    Baylor College of Medicine, Plant Physiology Group, United States Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Houston, Texas 77030, USA
    Plant Physiol 124:125-33. 2000
  5. ncbi Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase
    Lamia Benbrahim Tallaa
    Laboratory of Comparative Carcinogenesis, National Cancer Institute at National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 115:1454-9. 2007
  6. ncbi Sublethal cadmium intoxication in Arabidopsis thaliana impacts translation at multiple levels
    R Sormani
    Aix Marseille Universite, Laboratoire de Genetique et Biophysique des Plantes, F 13009 Marseille, France
    Plant Cell Physiol 52:436-47. 2011
  7. ncbi Molecular and cellular mechanisms of cadmium carcinogenesis
    Michael Waisberg
    Department of Land Resource Science, University of Guelph, Guelph, Ont, Canada
    Toxicology 192:95-117. 2003
  8. ncbi Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
    Daniel Stewart
    Department of Molecular Genetics, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    J Biol Chem 278:2396-402. 2003
  9. ncbi Cadmium is a mutagen that acts by inhibiting mismatch repair
    Yong Hwan Jin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Nat Genet 34:326-9. 2003
  10. ncbi Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4
    Marc Hanikenne
    Max Planck Institute of Molecular Plant Physiology, D 14476 Potsdam, Germany
    Nature 453:391-5. 2008

Research Grants

  1. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2009
  2. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2011
  3. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2010
  4. Divalent metal-ion transporter DMT1 and its role in intestinal metal-ion uptake
    Bryan Mackenzie; Fiscal Year: 2009
  5. Divalent metal-ion transporter DMT1 and its role in intestinal metal-ion uptake
    Bryan Mackenzie; Fiscal Year: 2010
  6. Divalent metal-ion transporter DMT1 and its role in intestinal metal-ion uptake
    Bryan Mackenzie; Fiscal Year: 2009
  7. INHALED PARTICLE CHARACTERISTICS AND EARLY LUNG EFFECTS
    William Beckett; Fiscal Year: 2002
  8. Role of Physico-chemical Properties in the Reprotoxicity of Inhaled Cd NP.
    Judith Zelikoff; Fiscal Year: 2009
  9. Role of Physico-chemical Properties in the Reprotoxicity of Inhaled Cd NP.
    JUDITH TERRY ZELIKOFF; Fiscal Year: 2010
  10. FUNCTIONAL ANALYSIS OF A LEAD/CADMIUM/ZINC ATPASE
    Bharati Mitra; Fiscal Year: 2007

Detail Information

Publications308 found, 100 shown here

  1. ncbi Current status of cadmium as an environmental health problem
    Lars Jarup
    Department of Epidemiology and Public Health, Imperial College London, London, UK
    Toxicol Appl Pharmacol 238:201-8. 2009
    b>Cadmium is a toxic metal occurring in the environment naturally and as a pollutant emanating from industrial and agricultural sources. Food is the main source of cadmium intake in the non-smoking population...
  2. ncbi Molecular mechanisms of metal hyperaccumulation in plants
    Nathalie Verbruggen
    Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    New Phytol 181:759-76. 2009
    ..This review presents key aspects of our current understanding of plant metal – in particular cadmium (Cd),nickel (Ni) and zinc (Zn) – hyperaccumulation.
  3. ncbi Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells
    Gaofeng Jiang
    Faculty of Preventive Medicine, Medical College, Wuhan University of Science and Technology, Huangjiahu Campus, Wuhan 430065, Hubei Province, People s Republic of China
    Toxicology 244:49-55. 2008
    b>Cadmium is a toxic transition metal of continuing occupational and environmental concern. As a well-recognized human carcinogen, its carcinogenic mechanisms are still poorly understood...
  4. ncbi Expression of arabidopsis CAX2 in tobacco. Altered metal accumulation and increased manganese tolerance
    K D Hirschi
    Baylor College of Medicine, Plant Physiology Group, United States Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Houston, Texas 77030, USA
    Plant Physiol 124:125-33. 2000
    ..These results suggest that CAX2 has a broad substrate range and modulation of this transporter may be an important component of future strategies to improve plant ion tolerance...
  5. ncbi Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase
    Lamia Benbrahim Tallaa
    Laboratory of Comparative Carcinogenesis, National Cancer Institute at National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 115:1454-9. 2007
    ..The typical pattern appears to involve reduced expression of maintenance DNA methyltransferase, DNMT1, inducing genomic hypomethylation, whereas increased expression of de novo DNMT3a or 3b causes gene-specific hypermethylation...
  6. ncbi Sublethal cadmium intoxication in Arabidopsis thaliana impacts translation at multiple levels
    R Sormani
    Aix Marseille Universite, Laboratoire de Genetique et Biophysique des Plantes, F 13009 Marseille, France
    Plant Cell Physiol 52:436-47. 2011
    ..regulation during heavy metal poisoning, Arabidopsis thaliana cell cultures were submitted to sublethal cadmium stress...
  7. ncbi Molecular and cellular mechanisms of cadmium carcinogenesis
    Michael Waisberg
    Department of Land Resource Science, University of Guelph, Guelph, Ont, Canada
    Toxicology 192:95-117. 2003
    b>Cadmium is a heavy metal, which is widely used in industry, affecting human health through occupational and environmental exposure...
  8. ncbi Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
    Daniel Stewart
    Department of Molecular Genetics, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    J Biol Chem 278:2396-402. 2003
    ..b>Cadmium did not significantly affect the steady-state level of Nrf2 mRNA or the initial rate of Nrf2 protein synthesis ..
  9. ncbi Cadmium is a mutagen that acts by inhibiting mismatch repair
    Yong Hwan Jin
    Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Nat Genet 34:326-9. 2003
    ..We found that chronic exposure of yeast to environmentally relevant concentrations of cadmium, a known human carcinogen, can result in extreme hypermutability...
  10. ncbi Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4
    Marc Hanikenne
    Max Planck Institute of Molecular Plant Physiology, D 14476 Potsdam, Germany
    Nature 453:391-5. 2008
    ..A. halleri naturally accumulates and tolerates leaf concentrations as high as 2.2% zinc and 0.28% cadmium in dry biomass. On the basis of transcriptomics studies, metal hyperaccumulation in A...
  11. ncbi Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway
    S H Wang
    Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan, ROC
    Cell Mol Life Sci 65:3640-52. 2008
    The cytotoxicity of cadmium (Cd) induced autophagy and apoptosis in MES-13 cells was determined by flow cytometry. Autophagy was also assessed by formation of autophagosomes and processing of LC3...
  12. ncbi Blood cadmium and lead and chronic kidney disease in US adults: a joint analysis
    Ana Navas-Acien
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Am J Epidemiol 170:1156-64. 2009
    Environmental cadmium and lead exposures are widespread, and both metals are nephrotoxic at high exposure levels...
  13. ncbi Root responses to cadmium in the rhizosphere: a review
    Alexander Lux
    Department of Plant Physiology, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina B2, 842 15 Bratislava, Slovakia
    J Exp Bot 62:21-37. 2011
    This article reviews the responses of plant roots to elevated rhizosphere cadmium (Cd) concentrations. Cadmium enters plants from the soil solution...
  14. ncbi Transgenic Indian mustard (Brassica juncea) plants expressing an Arabidopsis phytochelatin synthase (AtPCS1) exhibit enhanced As and Cd tolerance
    Ksenija Gasic
    Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana Champaign, 310 ERML, 1201 W Gregory Dr, Urbana, IL 61801, USA
    Plant Mol Biol 64:361-9. 2007
    ..mustard, and transgenic pcs lines have been compared with wild-type plants for tolerance to and accumulation of cadmium (Cd) and arsenic (As)...
  15. ncbi Interpreting NHANES biomonitoring data, cadmium
    Patricia Ruiz
    Agency for Toxic Substances and Disease Registry, Atlanta, GA 30333, USA
    Toxicol Lett 198:44-8. 2010
    b>Cadmium (Cd) occurs naturally in the environment and the general population's exposure to it is predominantly through diet...
  16. ncbi Cadmium stress: an oxidative challenge
    Ann Cuypers
    Centre for Environmental Sciences, Hasselt University, Agoralaan Building D, Diepenbeek, Belgium
    Biometals 23:927-40. 2010
    At the cellular level, cadmium (Cd) induces both damaging and repair processes in which the cellular redox status plays a crucial role...
  17. ncbi Nitric oxide is involved in cadmium-induced programmed cell death in Arabidopsis suspension cultures
    Roberto De Michele
    Dipartimento di Biologia, Universita degli Studi di Padova, I 35131 Padova, Italy
    Plant Physiol 150:217-28. 2009
    Exposure to cadmium (Cd(2+)) can result in cell death, but the molecular mechanisms of Cd(2+) cytotoxicity in plants are not fully understood...
  18. ncbi Localization of S-nitrosoglutathione and expression of S-nitrosoglutathione reductase in pea plants under cadmium stress
    Juan B Barroso
    Grupo de Señalización Molecular y Sistemas Antioxidantes en Plantas, Unidad Asociada al CSIC Estación Experimental del Zaidín, Área de Bioquímica y Biología Molecular, Universidad de Jaen, E 23071 Jaén, Spain
    J Exp Bot 57:1785-93. 2006
    ..scanning microscopy and HPLC, respectively, showed a marked decrease of both compounds in plants treated with cadmium. The analysis of the S-nitrosoglutathione reductase (GSNOR) activity and its transcript expression in leaves ..
  19. ncbi Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity
    Yuxia Cui
    Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC 27708, USA
    Genome Biol 8:R122. 2007
    Exposure to cadmium is associated with a variety of human diseases. At low concentrations, cadmium activates the transcription of stress-responsive genes, which can prevent or repair the adverse effects caused by this metal.
  20. ncbi Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium
    Patricia Rockwell
    Department of Biological Sciences, Hunter College of the City University of New York, New York, NY 10021, USA
    Cell Signal 16:343-53. 2004
    We reported previously that cadmium, an oxidative stressor, induced cyclooxygenase-2 (COX-2) upregulation in mouse neuronal cells that culminated in cell death...
  21. ncbi Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation
    Masufumi Takiguchi
    Inorganic Carcinogenesis Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute at the National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Exp Cell Res 286:355-65. 2003
    b>Cadmium is a human carcinogen that likely acts via epigenetic mechanisms...
  22. ncbi Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels
    Claire de Burbure
    Unit of Industrial Toxicology and Occupational Medicine, Faculty of Medicine, Catholic University of Louvain, Clos Chapelle-aux-Champs 30, B-1200 Brussels, Belgium
    Environ Health Perspect 114:584-90. 2006
    Lead, cadmium, mercury, and arsenic are common environmental pollutants in industrialized countries, but their combined impact on children's health is little known...
  23. ncbi Cadmium and mitochondria
    Giuseppe Cannino
    Dipartimento di Biologia Cellulare e dello Sviluppo A Monroy, University of Palermo, Italy
    Mitochondrion 9:377-84. 2009
    The heavy metal cadmium (Cd) a pollutant associated with several modern industrial processes, is absorbed in significant quantities from cigarette smoke, water, food and air contaminations...
  24. ncbi Acute metal stress in Populus tremula x P. alba (717-1B4 genotype): leaf and cambial proteome changes induced by cadmium 2+
    Thomas C Durand
    CRP Gabriel Lippmann, Department Environment and Agro Biotechnologies, Belvaux, GD, Luxembourg
    Proteomics 10:349-68. 2010
    ..alba (717-1B4 genotype) were analyzed after 61 days of exposure to cadmium (Cd) 360 mg/kg soil dry weight in pot-soil cultures...
  25. ncbi Heavy metal-regulated new microRNAs from rice
    Si Qi Huang
    Department of Biochemistry and Molecular Biology, College of Life Science, Nanjing Agricultural University, Nanjing, China
    J Inorg Biochem 103:282-7. 2009
    ..novel miRNAs, we constructed a library of small RNAs from rice seedlings that were exposed to toxic levels of cadmium (Cd(2+)). Sequencing of the library and subsequent analysis revealed 19 new miRNAs representing six families...
  26. ncbi Lung cancer risk associated with occupational exposure to nickel, chromium VI, and cadmium in two population-based case-control studies in Montreal
    Rachelle Beveridge
    Departement de Medecine sociale et preventive, Universite de Montreal, Montreal, QC, Canada
    Am J Ind Med 53:476-85. 2010
    Nickel, chromium VI, and cadmium have been identified as lung carcinogens in highly exposed cohorts...
  27. ncbi Fetal growth restriction is related to placental levels of cadmium, lead and arsenic but not with antioxidant activities
    Miguel N Llanos
    Laboratory of Nutrition and Metabolic Regulation, Institute of Nutrition and Food Technology INTA, University of Chile, Macul 5540, Casilla 138 11, Santiago, Chile
    Reprod Toxicol 27:88-92. 2009
    ..mercury, selenium and arsenic were measured by Instrumental Neutron Activation Analysis (INAA), and iron, copper, cadmium and lead by Atomic Absorption Spectrometry (AAS)...
  28. ncbi Tracing cadmium from culture to spikelet: noninvasive imaging and quantitative characterization of absorption, transport, and accumulation of cadmium in an intact rice plant
    Shu Fujimaki
    Plant Positron Imaging Group, Quantum Beam Science Directorate, Japan Atomic Energy Agency, Takasaki, Gunma 370 1292, Japan
    Plant Physiol 152:1796-806. 2010
    We characterized the absorption and short-term translocation of cadmium (Cd) in rice (Oryza sativa 'Nipponbare') quantitatively using serial images observed with a positron-emitting tracer imaging system...
  29. ncbi National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population
    Nam Soo Kim
    Institute of Environmental and Occupational Medicine, College of Medicine, Soonchunhyang University, 646 Eupnae ri, Shinchang myun, Asan, Choongnam, 336 745, Korea
    Int Arch Occup Environ Health 84:53-63. 2011
    To assess the extent of exposure to lead, cadmium, and mercury in the Korean general adult population using a representative sample.
  30. ncbi Mechanisms in cadmium-induced carcinogenicity: recent insights
    Andrea Hartwig
    Institut für Lebensmitteltechnologie und Lebensmittelchemie, Fachgebiet Lebensmittelchemie und Toxikologie, Technische Universitat Berlin, Berlin, Germany
    Biometals 23:951-60. 2010
    b>Cadmium is an environmental pollutant,with relevant exposures at workplaces and in the general population...
  31. ncbi OsHMA3, a P1B-type of ATPase affects root-to-shoot cadmium translocation in rice by mediating efflux into vacuoles
    Hidenori Miyadate
    Department of Biological Production, Faculty of Bioresource Sciences, Akita Prefectural University, Shimoshinjyo Nakano, Akita, Japan
    New Phytol 189:190-9. 2011
    The cadmium (Cd) over-accumulating rice (Oryza sativa) cv Cho-Ko-Koku was previously shown to have an enhanced rate of root-to-shoot Cd translocation. This trait is controlled by a single recessive allele located at qCdT7...
  32. ncbi A major quantitative trait locus for cadmium tolerance in Arabidopsis halleri colocalizes with HMA4, a gene encoding a heavy metal ATPase
    Mikael Courbot
    Laboratoire de Physiologie et de Génétique Moléculaire des Plantes, Universite Libre de Bruxelles, B 1050 Brussels, Belgium
    Plant Physiol 144:1052-65. 2007
    b>Cadmium (Cd) tolerance seems to be a constitutive species-level trait in Arabidopsis halleri sp. halleri. Therefore, an interspecific cross was made between A...
  33. ncbi Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor-positive breast cancer cells
    Xiankui Sun
    University of Michigan Medical School, Department of Cell and Developmental Biology, 3065 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI 48109 2200, USA
    Cell Stress Chaperones 12:307-19. 2007
    ..b>Cadmium (Cd) is an environmental pollutant with estrogenic properties (metalloestrogen) that has been implicated in ..
  34. ncbi Effects of soluble cadmium salts versus CdSe quantum dots on the growth of planktonic Pseudomonas aeruginosa
    John H Priester
    Donald Bren School of Environmental Science and Management, Department of Chemistry and Biochemistry, Earth Sciences, and Materials Research Laboratory, University of California, Santa Barbara, California 93106, USA
    Environ Sci Technol 43:2589-94. 2009
    ..ENMs, such as CdSe quantum dots (QDs), are toxic due to the release of dissolved heavy metals, but the effects of cadmium ions versus intact QDs are mostly unknown...
  35. ncbi Metallothionein protection of cadmium toxicity
    Curtis D Klaassen
    Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160 7417, USA
    Toxicol Appl Pharmacol 238:215-20. 2009
    The discovery of the cadmium (Cd)-binding protein from horse kidney in 1957 marked the birth of research on this low-molecular weight, cysteine-rich protein called metallothionein (MT) in Cd toxicology...
  36. ncbi Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
    Long Chen
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130 3932, USA
    Free Radic Biol Med 45:1035-44. 2008
    b>Cadmium (Cd), a highly toxic environmental pollutant, induces neurodegenerative diseases...
  37. ncbi Quantitative changes in protein expression of cadmium-exposed poplar plants
    Pol Kieffer
    Department Environment and Agrobiotechnologies, Centre de Recherche Public Gabriel Lippmann, Belvaux, Luxembourg
    Proteomics 8:2514-30. 2008
    b>Cadmium (Cd) pollution is a worldwide major concern having, among others, deleterious effects on plants...
  38. ncbi Role of oxidative stress, apoptosis, and intracellular homeostasis in primary cultures of rat proximal tubular cells exposed to cadmium
    Lin Wang
    College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, People s Republic of China
    Biol Trace Elem Res 127:53-68. 2009
    b>Cadmium (Cd) is a known nephrotoxic element. In this study, the primary cultures of rat proximal tubular (rPT) cells were treated with low doses of cadmium acetate (2.5 and 5 microM) to investigate its cytotoxic mechanism...
  39. ncbi Bioavailability of cadmium in inexpensive jewelry
    Jeffrey D Weidenhamer
    Department of Chemistry, Geology and Physics, Ashland University, Ashland, Ohio 44805, USA
    Environ Health Perspect 119:1029-33. 2011
    ..We evaluated the bioavailability of Cd in 86 components of 57 jewelry items found to contain high levels of Cd (> 10,000 ppm) by X-ray fluorescence (XRF), using extractions that simulate mouthing or swallowing of jewelry items...
  40. ncbi Cadmium exposure in the population: from health risks to strategies of prevention
    Tim S Nawrot
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Biometals 23:769-82. 2010
    We focus on the recent evidence that elucidates our understanding about the effects of cadmium (Cd) on human health and their prevention...
  41. ncbi AtOSA1, a member of the Abc1-like family, as a new factor in cadmium and oxidative stress response
    Michal Jasinski
    University of Zurich, Institute of Plant Biology, 8008 Zurich, Switzerland
    Plant Physiol 147:719-31. 2008
    ..Our data suggest that the chloroplast AtOSA1 protein is a new factor playing a role in the balance of oxidative stress...
  42. ncbi Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis
    Marta Biagioli
    Laboratory of Cellular and Development Biology, Department of Biology, University of Pisa, Italy
    Cell Calcium 43:184-95. 2008
    b>Cadmium, a toxic environmental contaminant, exerts adverse effects on different cellular pathways such as cell proliferation, DNA damage and apoptosis...
  43. ncbi Chronic exposure to cadmium and arsenic strongly influences concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine in urine
    Karin S Engström
    Section of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 85 Lund, Sweden
    Free Radic Biol Med 48:1211-7. 2010
    Exposure to arsenic (As), cadmium (Cd), and lead (Pb) may generate oxidative stress, which can be assessed by 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) in urine, a sensitive marker of oxidatively damaged DNA...
  44. ncbi The vascular endothelium as a target of cadmium toxicity
    Walter C Prozialeck
    Department of Pharmacology, Midwestern University, 555 31st Street, Downers Grove, IL 60515, United States
    Life Sci 79:1493-506. 2006
    b>Cadmium (Cd) is an important industrial and environmental pollutant that can produce a wide variety of adverse effects in humans and animals...
  45. ncbi The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene
    S J Langmade
    Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Biol Chem 275:34803-9. 2000
    ..Zinc or cadmium treatment of cell lines rapidly (3 h) and dramatically (about 12-fold) induced ZnT1 mRNA levels...
  46. ncbi Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways
    F Thevenod
    II Department of Physiology, University of Saarland, D 66421 Homburg, Germany
    FASEB J 13:1751-61. 1999
    The mechanisms of cadmium (Cd)-dependent nephrotoxicity were studied in a rat proximal tubule (PT) cell line...
  47. ncbi Cellular response of pea plants to cadmium toxicity: cross talk between reactive oxygen species, nitric oxide, and calcium
    María Rodríguez-Serrano
    Departamento de Bioquimica, Biologia Celular y Molecular de Plantas, Estacion Experimental del Zaidin, Consejo Superior de Investigaciones Cientificas, E 18008 Granada, Spain
    Plant Physiol 150:229-43. 2009
    b>Cadmium (Cd) toxicity has been widely studied in different plant species; however, the mechanism involved in its toxicity as well as the cell response against the metal have not been well established...
  48. ncbi Mechanisms to cope with arsenic or cadmium excess in plants
    Nathalie Verbruggen
    Laboratoire de Physiologie et de Génétique Moléculaire des Plantes, Faculte des Sciences, Universite Libre de Bruxelles, Campus Plaine, Brussels, Belgium
    Curr Opin Plant Biol 12:364-72. 2009
    The metalloid arsenic and the heavy metal cadmium have no demonstrated biological function in plants. Both elements are highly toxic and of major concern with respect to their accumulation in soils, in the food-chain or in drinking water...
  49. ncbi A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation
    Seon-Hee Oh
    Research Center for Resistant Cells, College of Medicine, Chosun University, Seosuk-dong, Dong-gu, Gwangju 501-759, South Korea
    Toxicol Appl Pharmacol 212:212-23. 2006
    Although reactive oxygen species (ROS) have been implicated in cadmium (Cd)-induced hepatotoxicity, the role of ROS in this pathway remains unclear...
  50. ncbi Carbon monoxide alleviates cadmium-induced oxidative damage by modulating glutathione metabolism in the roots of Medicago sativa
    Yi Han
    College of Life Sciences, Co Laboratory of Nanjing Agricultural University and Carl Zeiss Far East, Nanjing Agricultural University, Nanjing 210095, PR China
    New Phytol 177:155-66. 2008
    Using pharmacological and biochemical approaches, the role of cadmium (Cd)-induced carbon monoxide (CO) release and the relationship between CO and oxidative stress conferred by Cd exposure in the root tissues of alfalfa (Medicago sativa)..
  51. ncbi Investigating heavy-metal hyperaccumulation using Thlaspi caerulescens as a model system
    Matthew J Milner
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
    Ann Bot 102:3-13. 2008
    ..caerulescens, has been widely studied for its remarkable properties to tolerate toxic levels of zinc (Zn), cadmium (Cd) and sometimes nickel (Ni) in the soil, and accumulate these metals to very high levels in the shoot...
  52. ncbi Toxic and essential elements in placentas of Swedish women
    K Osman
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Clin Biochem 33:131-8. 2000
    ..To evaluate interactions between toxic and essential elements in the mother-fetus relationship and possible predictors of trace element concentrations in placenta and cord blood...
  53. ncbi Cadmium-induced changes in antioxidative systems, hydrogen peroxide content, and differentiation in Scots pine roots
    A Schützendübel
    Forstbotanisches Institut, Abteilung I Forstbotanik und Baumphysiologie, Georg August Universitat Gottingen, Büsgenweg 2, 37077 Gottingen, Germany
    Plant Physiol 127:887-98. 2001
    ..This, in turn, may have triggered the developmental program leading to xylogenesis. In conclusion, Cd did not cause necrotic injury in root tips but appeared to expedite differentiation, thus leading to accelerated aging...
  54. ncbi Regulation of metallothionein gene expression by oxidative stress and metal ions
    G K Andrews
    Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City 66160 7421, USA
    Biochem Pharmacol 59:95-104. 2000
    ..Transcription of these genes is rapidly and dramatically up-regulated in response to zinc and cadmium, as well as in response to agents which cause oxidative stress and/or inflammation...
  55. ncbi Cadmium: toxic effects on the reproductive system and the embryo
    Jennifer Thompson
    School of Medicine and Medical Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Reprod Toxicol 25:304-15. 2008
    The heavy metal cadmium (Cd) is a pollutant associated with several modern industrial processes...
  56. ncbi Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts
    Chwen Ming Shih
    Department of Biochemistry, School of Medicine, Taipei Medical University, Taipei, Taiwan, ROC
    J Cell Biochem 91:384-97. 2004
    b>Cadmium (Cd) is an environmental pollutant of global concern with a 10-30-year biological half-life in humans. Accumulating evidence suggests that the lung is one of the major target organs of inhaled Cd compounds...
  57. ncbi Mitochondria, reactive oxygen species and cadmium toxicity in the kidney
    Glenda Gobe
    Centre for Kidney Disease Research, University of Queensland School of Medicine, Princess Alexandra Hospital, Woolloongabba, Brisbane 4102, Australia
    Toxicol Lett 198:49-55. 2010
    The heavy metal cadmium accumulates in kidney cells, particularly those of the proximal tubular epithelium, and the damage this causes is associated with development of chronic kidney disease...
  58. ncbi Reproduction and biochemical responses in Enchytraeus albidus (Oligochaeta) to zinc or cadmium exposures
    Sara C Novais
    CESAM and Department of Biology, University of Aveiro, 3810 193 Aveiro, Portugal
    Environ Pollut 159:1836-43. 2011
    ..The main goal of this study was to investigate the effects of zinc and cadmium on survival and reproduction of E...
  59. ncbi Estrogen-like effects of cadmium in vivo do not appear to be mediated via the classical estrogen receptor transcriptional pathway
    Imran Ali
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 118:1389-94. 2010
    b>Cadmium (Cd), a ubiquitous food contaminant, has been proposed to be an endocrine disruptor by inducing estrogenic responses in vivo. Several in vitro studies suggested that these effects are mediated via estrogen receptors (ERs).
  60. ncbi Effects of elevated temperature and cadmium exposure on stress protein response in eastern oysters Crassostrea virginica (Gmelin)
    A V Ivanina
    Department of Biology, University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC 28223, USA
    Aquat Toxicol 91:245-54. 2009
    ..virginica are commonly exposed to multiple stressors including temperature and pollution by metals such as cadmium (Cd) in estuaries and coastal zones; however, the combined effects of these stressors on their cellular ..
  61. ncbi Nitric oxide modulates cadmium influx during cadmium-induced programmed cell death in tobacco BY-2 cells
    Wenwen Ma
    Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, People s Republic of China
    Planta 232:325-35. 2010
    ..gas and functions as a signaling molecule in plants exposed to diverse biotic and abiotic stresses including cadmium (Cd(2+))...
  62. ncbi Cadmium stress alters gene expression of DNA mismatch repair related genes in Arabidopsis seedlings
    W Liu
    Cardiff University, School of Earth Sciences, Cardiff CF10 3YE, UK
    Chemosphere 73:1138-44. 2008
    b>Cadmium (Cd) is a non essential element, and is a widespread environmental pollutant. Exposure to Cd can result in a variety of adverse health effects in plant and humans...
  63. ncbi Cadmium levels in urine and mortality among U.S. adults
    Andy Menke
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 117:190-6. 2009
    b>Cadmium exposure has been associated with increased all-cause, cancer, and cardiovascular disease mortality...
  64. ncbi Determination of arsenic, cadmium, mercury, and lead by inductively coupled plasma/mass spectrometry in foods after pressure digestion: NMKL interlaboratory study
    Kaare Julshamn
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway
    J AOAC Int 90:844-56. 2007
    ..in an interlaboratory method performance (collaborative) study on a method for the determination of arsenic, cadmium, mercury, and lead by inductively coupled plasma/mass spectrometry (ICP/MS) after pressure digestion including ..
  65. ncbi Cadmium induces retinoic acid signaling by regulating retinoic acid metabolic gene expression
    Yuxia Cui
    Comparative Genomics Group, Laboratory of Molecular Toxicology, NIEHS, National Institutes of Health, Durham, North Carolina 27709, USA
    J Biol Chem 284:24925-32. 2009
    The transition metal cadmium is an environmental teratogen. In addition, cadmium and retinoic acid can act synergistically to induce forelimb malformations...
  66. ncbi The NRAMP6 metal transporter contributes to cadmium toxicity
    Rémy Cailliatte
    Laboratoire de Biochimie et Physiologie Moléculaire des Plantes CNRS UMR5004, Institut de Biologie Integrative des Plantes, F 34060 Montpellier, France
    Biochem J 422:217-28. 2009
    ..When expressed in yeast, AtNRAMP6, but not its misspliced derivative, increased sensitivity to cadmium without affecting cadmium content in the cell...
  67. ncbi Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors
    Jiyoung Kim
    Program in Toxicology, Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602-7389, USA
    J Toxicol Environ Health A 69:1181-201. 2006
    b>Cadmium is a toxic heavy metal that accumulates in the environment and is commonly found in cigarette smoke and industrial effluents...
  68. ncbi Prevalence of kidney dysfunction in humans - relationship to cadmium dose, metallothionein, immunological and metabolic factors
    Gunnar F Nordberg
    Environmental Medicine, Department of Public Health and Clinical Medicine, Umea University, SE 90187 Umea, Sweden
    Biochimie 91:1282-5. 2009
    Long term cadmium (Cd) exposure in occupational and general environments may give rise to kidney dysfunction. This effect is usually considered to be the critical effect, i. e. the effect that occurs at relatively low level of exposure...
  69. ncbi Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity
    Walter C Prozialeck
    Department of Pharmacology, Midwestern University, Downers Grove, IL 60515, USA
    Toxicol Appl Pharmacol 238:301-5. 2009
    ..These results provide additional evidence that Kim-1 is a sensitive biomarker of the early stages of Cd-induced proximal tubule injury...
  70. ncbi Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death
    Long Chen
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130 3932, USA
    Free Radic Biol Med 50:624-32. 2011
    b>Cadmium (Cd), a highly toxic environmental pollutant, induces neurodegenerative diseases. Recently we have demonstrated that Cd induces neuronal apoptosis in part through activation of the mammalian target of rapamycin (mTOR) pathway...
  71. ncbi Cadmium and cellular signaling cascades: to be or not to be?
    Frank Thevenod
    Department of Physiology and Pathophysiology, University of Witten Herdecke, Witten, Germany
    Toxicol Appl Pharmacol 238:221-39. 2009
    The cellular effects of the toxic metal cadmium (Cd) are manifold. A large proportion of the cellular reactions affected by ionic Cd(2+) are mediated by cellular signaling cascades...
  72. ncbi Proteomic analysis of Arabidopsis halleri shoots in response to the heavy metals cadmium and zinc and rhizosphere microorganisms
    Silvia Farinati
    Department of Biotechnology, University of Verona, Verona, Italy
    Proteomics 9:4837-50. 2009
    ..The aim of this study was to analyze the effect of plant-microbe interaction on the accumulation of cadmium (Cd) and zinc (Zn) in shoots of an ecotype of A...
  73. ncbi Expressional control of a cadmium-transporting P1B-type ATPase by a metal sensing degradation signal
    David J Adle
    Redox Biology Center, Department of Biochemistry, University of Nebraska, Lincoln, Nebraska 68588 0664, USA
    J Biol Chem 283:31460-8. 2008
    b>Cadmium is a highly toxic environmental contaminant implicated in various diseases. Our previous data demonstrated that Pca1, a P1B-type ATPase, plays a critical role in cadmium resistance in yeast S...
  74. ncbi Biosurfactant technology for remediation of cadmium and lead contaminated soils
    Asha A Juwarkar
    Environmental Biotechnology Division, National Environmental Engineering Research Institute NEERI, Nehru Marg, Nagpur 440 020, India
    Chemosphere 68:1996-2002. 2007
    ..This study shows that biosurfactant technology can be an effective and nondestructive method for bioremediation of cadmium and lead contaminated soil.
  75. ncbi The Arabidopsis nitrate transporter NRT1.8 functions in nitrate removal from the xylem sap and mediates cadmium tolerance
    Jian Yong Li
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People s Republic of China
    Plant Cell 22:1633-46. 2010
    ..Interestingly, NRT1.8 was the only nitrate assimilatory pathway gene that was strongly upregulated by cadmium (Cd(2+)) stress in roots, and the nrt1.8-1 mutant showed a nitrate-dependent Cd(2+)-sensitive phenotype...
  76. ncbi Cadmium-induced heme oxygenase-1 gene expression is associated with the depletion of glutathione in the roots of Medicago sativa
    Weiti Cui
    College of Life Sciences, Cooperative Demonstration Laboratory of Centrifuge Technique, Nanjing Agricultural University, Nanjing 210095, People s Republic of China
    Biometals 24:93-103. 2011
    Following previous findings that cadmium (Cd) induces heme oxygenase-1 (HO1) gene expression in alfalfa seedling roots, we now show that the decreased glutathione (GSH) and ascorbic acid (AsA) contents, induction of HO-1 gene expression ..
  77. ncbi The Pmr1 protein, the major yeast Ca2+-ATPase in the Golgi, regulates intracellular levels of the cadmium ion
    Cláudio Marcos Lauer Júnior
    Departamento de Biofisica Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul UFRGS, Porto Alegre, RS, Brazil
    FEMS Microbiol Lett 285:79-88. 2008
    b>Cadmium is a nonessential, highly toxic heavy metal that shows ionic properties similar to calcium...
  78. ncbi A cadmium-transporting P1B-type ATPase in yeast Saccharomyces cerevisiae
    David J Adle
    Redox Biology Center, Department of Biochemistry, University of Nebraska, Lincoln, Nebraska 68588 0664, USA
    J Biol Chem 282:947-55. 2007
    ..Overexpression or deletion of the functional allele in yeast demonstrates that PCA1 is a cadmium efflux pump...
  79. ncbi Cadmium levels in Europe: implications for human health
    Jilang Pan
    Imperial College London, London, UK
    Environ Geochem Health 32:1-12. 2010
    ..study we used the Forum of European Geological Surveys geochemical baseline data to examine the distribution of cadmium (Cd) in Europe, with a particular reference to the international soil and water guideline values...
  80. ncbi Development of a flow system for the determination of cadmium in fuel alcohol using vermicompost as biosorbent and flame atomic absorption spectrometry
    Joyce Nunes Bianchin
    Departamento de Quimica, Universidade Federal de Santa Catarina, Florianópolis 88040900, SC, Brazil
    Talanta 78:333-6. 2009
    In this study a method for the determination of cadmium in fuel alcohol using solid-phase extraction with a flow injection analysis system and detection by flame atomic absorption spectrometry was developed...
  81. ncbi Proteomic analysis of cadmium-induced protein profile alterations from marine alga Nannochloropsis oculata
    Y K Kim
    Division of Life Science, Soonchunhyang University, PO Box 97, 336-600, Asan, Chungnam, Korea
    Ecotoxicology 14:589-96. 2005
    Protein profile alterations following exposure to cadmium were examined in marine alga Nannochloropsis oculata through proteomic analysis...
  82. ncbi Trace elements and cancer risk: a review of the epidemiologic evidence
    Stephanie A Navarro Silvera
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Room 1301a, New York, NY 10461, USA
    Cancer Causes Control 18:7-27. 2007
    ..Trace elements, such as selenium, zinc, arsenic, cadmium, and nickel, are found naturally in the environment, and human exposure derives from a variety of sources, ..
  83. ncbi Genotoxic effects of occupational exposure to lead and cadmium
    J Palus
    Department of Toxicology and Carcinogenesis, Nofer Institute of Occupational Medicine, Lodz, Poland
    Mutat Res 540:19-28. 2003
    ..in somatic cells of workers in a Polish battery plant after high-level occupational exposure to lead (Pb) and cadmium (Cd), by use of the following techniques: the micronucleus (MN) assay, combined with in situ fluorescence ..
  84. ncbi Usefulness of biomarkers of exposure to inorganic mercury, lead, or cadmium in controlling occupational and environmental risks of nephrotoxicity
    H A Roels
    Industrial Toxicology and Occupational Medicine Unit, School of Public Health, Brussels, Belgium
    Ren Fail 21:251-62. 1999
    ..diseases induced by occupational or environmental exposure to toxic metals such as mercury (Hg), lead (Pb), or cadmium (Cd) largely relies on the capability to detect nephrotoxic effects at a stage when they are still reversible or ..
  85. ncbi Cadmium affects muscle type development and axon growth in zebrafish embryonic somitogenesis
    Elly Suk Hen Chow
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Toxicol Sci 73:149-59. 2003
    We have previously reported that exposure to cadmium during zebrafish embryonic development caused morphological malformations of organs and ectopic expression of genes involved in regulating developmental process...
  86. ncbi Copper and cadmium increase laccase activity in Pleurotus ostreatus
    Petr Baldrian
    Laboratory of Biochemistry of the Wood rotting Fungi, Institute of Microbiology, ASCR, Videnska 1083, 14220 4, Prague, Czech Republic
    FEMS Microbiol Lett 206:69-74. 2002
    Addition of copper (0.5-5 mM) or cadmium (1-5 mM) to the white rot fungus Pleurotus ostreatus cultivated in liquid nitrogen-limited medium for 12 days increased the activity of laccase. The addition of 2 mM Cd led to an 18...
  87. ncbi Cadmium affects genes involved in growth regulation during two-stage transformation of Balb/3T3 cells
    Ming Zhu Fang
    Laboratory of Toxicology, College of Veterinary Medicine, Seoul National University, Suwon, South Korea
    Toxicology 177:253-65. 2002
    b>Cadmium (Cd), a carcinogenic metal in human and rodents, has been shown to transform cells in vitro. However, the carcinogenic mechanisms of Cd as a mutagen and/or promoter are not well clarified...
  88. ncbi Gene response profiles for Daphnia pulex exposed to the environmental stressor cadmium reveals novel crustacean metallothioneins
    Joseph R Shaw
    Department of Biology, Dartmouth College, Hanover, New Hampshire 03755, USA
    BMC Genomics 8:477. 2007
    ..species Daphnia pulex, to identify genes whose regulation is modulated following exposure to the metal stressor cadmium. Our experiments revealed interesting changes in gene transcription that suggest their biological roles and their ..
  89. ncbi Characterization of multiple members of the HSP70 family in platyfish culture cells: molecular evolution of stress protein HSP70 in vertebrates
    Michiaki Yamashita
    Institute for Frontier Medical Science, Kyoto University, Kyoto 606 8507, Japan
    Gene 336:207-18. 2004
    ....
  90. ncbi Molecular mechanisms of proline-mediated tolerance to toxic heavy metals in transgenic microalgae
    Surasak Siripornadulsil
    Biophysics Program, Ohio State University, Columbus, Ohio 43210, USA
    Plant Cell 14:2837-47. 2002
    ..The resulting increased GSH levels facilitate increased phytochelatin synthesis and sequestration of Cd, because GSH-heavy metal adducts are the substrates for phytochelatin synthase...
  91. ncbi Mediation of cadmium-induced oxidative damage and glucose-6-phosphate dehydrogenase expression through glutathione depletion
    Jun Xu
    Department of Chemistry, Western Michigan University, Kalamazoo, MI 49008, USA
    J Biochem Mol Toxicol 17:67-75. 2003
    The effect of cadmium (Cd), a significant environmental contaminant, on the expression of glucose-6-phosphate dehydrogenase (G6PDH), has been investigated...
  92. ncbi A biomonitoring study of lead, cadmium, and mercury in the blood of New York city adults
    Wendy McKelvey
    Division of Environmental Health, New York City Department of Health and Mental Hygiene, New York, New York 10007, USA
    Environ Health Perspect 115:1435-41. 2007
    We assessed the extent of exposure to lead, cadmium, and mercury in the New York City (NYC) adult population.
  93. ncbi Metals and arsenic in soils and corresponding vegetation at Central Elbe river floodplains (Germany)
    M Overesch
    Department for Geo and Agroecology, Institute of Spatial Analysis and Planning in Areas of Intensive Agriculture, University of Vechta, P O Box 1553, D 49364 Vechta, Germany
    Environ Pollut 145:800-12. 2007
    ..To limit harmful transfers into the food chain, low-lying terraces and flood channels revealing highest contaminations or phytoavailabilities should be excluded from mowing and grazing...
  94. ncbi Adsorption and redox reactions of heavy metals on synthesized Mn oxide minerals
    Xiong Han Feng
    Key Lab of Subtropical Agriculture Resource and Environment, Ministry of Agriculture, Huazhong Agricultural University, Wuhan, China
    Environ Pollut 147:366-73. 2007
    ..The maximum amounts of Cr(III) oxidized by the Mn oxide minerals in order were (mmol/kg): birnessite (1330.0)>cryptomelane (422.6)>todorokite (59.7)>hausmannite (36.6)...
  95. ncbi Use of a glass residue in the removal of heavy metals from wastewater
    Paola Catalfamo
    Dipartimento di Chimica Industriale e Ingegneria dei Materiali, , Italia
    Ann Chim 96:487-92. 2006
    ..Sodium and calcium ions take the place of heavy metals in water while pH keeps almost neutral. The exchange mechanism was identified...
  96. ncbi A 1500-year record of lead, copper, arsenic, cadmium, zinc level in Antarctic seal hairs and sediments
    Xuebin Yin
    Institute of Polar Environment, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China
    Sci Total Environ 371:252-7. 2006
    ..levels in the South Ocean ecosystem of Antarctica, the concentrations of lead (Pb), copper (Cu), arsenic (As), cadmium (Cd), and zinc (Zn) in seal hairs and lake sediments spanning the past 1500 years from Fildes Peninsula of King ..
  97. ncbi Mobility of heavy metals as related to soil chemical and mineralogical characteristics of Brazilian soils
    A T de Matos
    Departamento de Engenharia Agricola, , , Brazil
    Environ Pollut 111:429-35. 2001
    ..characteristics of one Oxisol and two Ultisols were related to the retardation factors (Rf) for zinc (Zn), cadmium (Cd), copper (Cu) and lead (Pb)...
  98. ncbi Risk assessment of heavy metal contamination in shrimp farming in Mai Po Nature Reserve, Hong Kong
    K C Cheung
    Croucher Institute for Environmental Science, and Department of Biology, Hong Kong Baptist University, Hong Kong SAR, China
    Environ Geochem Health 28:27-36. 2006
    ..sites contained higher nutrient contents, as well as zinc (Zn), chromium (Cr), copper (Cu), nickel (Ni) and cadmium (Cd) than those collected from the seaward sites, but vice versa for lead (Pb) and mercury (Hg)...
  99. ncbi Heavy metals in wetland plants and soil of Lake Taihu, China
    Hongjun Yang
    School of Environmental Science and Engineering, Shanghai Jiao Tong University, China
    Environ Toxicol Chem 27:38-42. 2008
    ..3 and 15.8, respectively. Aquatic-terrestrial ecotone plants are more effective in controlling Cu pollution than other heavy metals. This will be very significant for ATE reestablishment near Cu-polluted sites...
  100. ncbi Evaluation of extractants for estimation of the phytoavailable trace metals in soils
    Neal W Menzies
    School of Land and Food Sciences, The University of Queensland, St Lucia, QLD 4072, Australia
    Environ Pollut 145:121-30. 2007
    ..01 M CaCl(2) and 0.1 M NaNO(3)) provide the most useful indication of metal phytoavailability across a range of metals of interest, although further research is required...
  101. ncbi Metal concentrations in edible mushrooms following municipal sludge application on forest land
    Mohammed Benbrahim
    Institut National de la Recherche Agronomique, , UR 911 INRA, Domaine de l'Hermitage, Route d'Arcachon, 33610 Gazinet-Cestas, France
    Environ Pollut 144:847-54. 2006
    ..This effect is dependent on sludge type and sites...

Research Grants94

  1. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2009
    ..It is based upon a growing epidemiological literature, by us and others, indicating that exposure to lead, cadmium, or arsenic increases cardiovascular risk...
  2. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2011
    ..It is based upon a growing epidemiological literature, by us and others, indicating that exposure to lead, cadmium, or arsenic increases cardiovascular risk...
  3. Lead, Cadmium,Arsenic, and cardiovascular risk in children
    Eliseo Guallar; Fiscal Year: 2010
    ..It is based upon a growing epidemiological literature, by us and others, indicating that exposure to lead, cadmium, or arsenic increases cardiovascular risk...
  4. Divalent metal-ion transporter DMT1 and its role in intestinal metal-ion uptake
    Bryan Mackenzie; Fiscal Year: 2009
    ..Important for this proposal, iron deficiency is a serious risk factor for cadmium intoxication, suggesting that cadmium and iron share a common absorptive mechanism...
  5. Divalent metal-ion transporter DMT1 and its role in intestinal metal-ion uptake
    Bryan Mackenzie; Fiscal Year: 2010
    ..Important for this proposal, iron deficiency is a serious risk factor for cadmium intoxication, suggesting that cadmium and iron share a common absorptive mechanism...
  6. Divalent metal-ion transporter DMT1 and its role in intestinal metal-ion uptake
    Bryan Mackenzie; Fiscal Year: 2009
    ..Important for this proposal, iron deficiency is a serious risk factor for cadmium intoxication, suggesting that cadmium and iron share a common absorptive mechanism...
  7. INHALED PARTICLE CHARACTERISTICS AND EARLY LUNG EFFECTS
    William Beckett; Fiscal Year: 2002
    ..shown an excess of COPD associated with dusty work environments, yet only a few substances (coal, silica, cadmium) causing COPD in the workplace have been characterized based on chemical composition and respirable particle size...
  8. Role of Physico-chemical Properties in the Reprotoxicity of Inhaled Cd NP.
    Judith Zelikoff; Fiscal Year: 2009
    ..Most non-carbon NP contain one or more toxicologically-active metals, including cadmium (Cd)...
  9. Role of Physico-chemical Properties in the Reprotoxicity of Inhaled Cd NP.
    JUDITH TERRY ZELIKOFF; Fiscal Year: 2010
    ..Most non-carbon NP contain one or more toxicologically-active metals, including cadmium (Cd)...
  10. FUNCTIONAL ANALYSIS OF A LEAD/CADMIUM/ZINC ATPASE
    Bharati Mitra; Fiscal Year: 2007
    ..essential trace metals like copper, zinc, cobalt and nickel, and mediate resistance to toxic metals such as lead, cadmium and silver...
  11. MODULATION OF CHOROID PLEXUS CHOLINE TRANSPORT BY METALS
    Alice Villalobos; Fiscal Year: 2002
    ..The objective of this proposal is to characterize modulation of choroid plexus choline transport by zinc and cadmium as a means to predict the potential for heavy metals to alter choline availability in the brain...
  12. FUNCTIONAL ANALYSIS OF A LEAD/CADMIUM/ZINC ATPASE
    Bharati Mitra; Fiscal Year: 2010
    ..essential trace metals like copper, zinc, cobalt and nickel, and mediate resistance to toxic metals such as lead, cadmium and silver...
  13. The association of lead and cadmium exposure with kidney function in children
    Jeffrey Fadrowski; Fiscal Year: 2007
    ..Recent research suggests environmental exposure to lead or cadmium, even at levels considered "non-toxic" by current federal government standards, potentially accelerates kidney ..
  14. Mechanisms for Adverse Renal Effects from Lead Exposure
    Virginia Weaver; Fiscal Year: 2006
    ..We are investigating a broad set of causes of renal function decline, including lead and cadmium dose, blood pressure, diabetes, and age, in a longitudinal study of current and former Korean lead workers and ..
  15. A SOCIAL NETWORK-BASED INTERVENTION TO REDUCE LEAD EXPOS
    Michelle Kegler; Fiscal Year: 2004
    ..The proposed research builds on previous work with these tribes, by expanding to address cadmium in addition to lead, and by adding a youth component...
  16. Toxic Metal Complexation by de Novo Designed Peptides
    Vincent L Pecoraro; Fiscal Year: 2010
    Abstract Heavy metal poisoning by elements such as mercury, lead, cadmium, and arsenic is a significant human health problem...
  17. Dietary and Environmental Exposure to Cadmium and the Risk of Endometrial Cancer
    Rudolph P Rull; Fiscal Year: 2010
    ..b>Cadmium is a trace metal released into air and soil as a byproduct of industrial processes and is perhaps the most potent ..
  18. Catalytic DNA Biosensor for Toxic Metal Ions
    Yi Lu; Fiscal Year: 2005
    ..real-time, and cost-effective detection and quantification of multiple heavy metal ions, such as mercury, cadmium and lead, simultaneously will be explored...
  19. Portable Analyzer for On-site Monitoring of Worker Exposure to Toxic Metals
    Charles Timchalk; Fiscal Year: 2007
    Large numbers of industrial workers are regularly exposed to toxic heavy metals like cadmium (Cd), lead (Pb), and mercury (Hg), which are known to induce various diseases that are detrimental to human health...
  20. Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging Cohort
    Joel Schwartz; Fiscal Year: 2009
    ..the increased risk of CVD observed in subjects exposed to air particles and toxic metals (such as arsenic, cadmium and lead) is mediated by alterations of DNA-methylation patterns is unresolved...
  21. Understanding the Effects of Cadmium on Breast Cancer Cell Growth
    Maggie Louie; Fiscal Year: 2007
    ..A potential mechanism may involve endocrine disruptors including heavy metals such as cadmium. Studies have suggested that cadmium may enhance the ER function and promote the development of breast cancer...
  22. Epigenetic Effects of Particles and Metals on Cardiac Health of an Aging Cohort
    Joel Schwartz; Fiscal Year: 2007
    ..the increased risk of CVD observed in subjects exposed to air particles and toxic metals (such as arsenic, cadmium and lead) is mediated by alterations of DNA-methylation patterns is unresolved...
  23. Environmental & Genetic Risk Factors for Renal Function
    Virginia Weaver; Fiscal Year: 2009
    ..exposures has received relatively little attention in this regard, despite the fact that exposures such as cadmium and lead are known renal toxicants that are stored long-term in the body and ubiquitous in humans...
  24. Lung Lysyl Oxidase Regulation by Metal Ion Homeostasis
    Wande Li; Fiscal Year: 2009
    ..Chronic exposure of humans to cadmium (Cd), a heavy metal, either from occupational contamination or from cigarette smoke, induces emphysema and lung ..