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Genomes and Genes | rubidiumSummarySummary: An element that is an alkali metal. It has an atomic symbol Rb, atomic number 37, and atomic weight 85.47. It is used as a chemical reagent and in the manufacture of photoelectric cells. Top Publications
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The potassium transporter AtHAK5 functions in K(+) deprivation-induced high-affinity K(+) uptake and AKT1 K(+) channel contribution to K(+) uptake kinetics in Arabidopsis rootsMarkus Gierth
Division of Biological Sciences, Cell and Developmental Biology Section and Center for Molecular Genetics, University of California San Diego, La Jolla, California 92093 0116, USA
Plant Physiol 137:1105-14. 2005..The results demonstrate an in vivo function for AtHAK5 in the inducible high-affinity K(+) uptake system in Arabidopsis roots...
Structure of the hydrated and dimethyl sulfoxide solvated rubidium ions in solutionIngmar Persson
Dipartimento di Chimica, , Piazzale Aldo Moro 5, I-00185 Rome, Italy
Inorg Chem 43:3543-9. 2004The structure of the hydrated and the dimethyl sulfoxide solvated rubidium ions in solution has been determined by means of large-angle X-ray scattering (LAXS) and extended X-ray absorption fine structure (EXAFS) studies...- Regulation of Na+-K+-2Cl- cotransport by protein phosphorylation in ferret erythrocytesP W Flatman
Membrane Biology Group, Department of Biomedical Sciences, University Medical School, Teviot Place, Edinburgh EH8 9AG, UK
J Physiol 517:699-708. 1999..Phosphorylation of the phosphatase is probably regulated by members of the Src family of tyrosine kinases... - Activation of ferret erythrocyte Na+-K+-2Cl- cotransport by deoxygenationPeter W Flatman
Membrane Biology Group, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh EH8 9XD, Scotland, UK
J Physiol 563:421-31. 2005..They also indicate that more than one kinase and phosphatase are involved in cotransporter phosphorylation... - Hydrogen peroxide mediates plant root cell response to nutrient deprivationRyoung Shin
Donald Danforth Plant Science Center, St Louis, MO 63132, USA
Proc Natl Acad Sci U S A 101:8827-32. 2004..ROS production is an early root response to K(+) deficiency that modulates gene expression and physiological changes in the kinetics of K(+) uptake... - The ionic environment controls the contribution of the barley HvHAK1 transporter to potassium acquisitionFabiana R Fulgenzi
Instituto de Investigaciones Biotecnologicas, Universidad Nacional de San Martín Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Tecnología Industrial, San Martin 1650, Provincia de Buenos Aires, Argentina
Plant Physiol 147:252-62. 2008..It is shown that the yeast protein phosphatase PPZ1 as well as the halotolerance HAL4/HAL5 kinases negatively regulate the HvHAK1-mediated K+ transport... - Energetic optimization of ion conduction rate by the K+ selectivity filterJ H Morais Cabral
Department of Molecular Biophysics and Biochemistry, Yale University, 260 Whitney Avenue, New Haven, Connecticut 06520, USA
Nature 414:37-42. 2001..The energetic balance between these configurations is a clear example of evolutionary optimization of protein function... - Adenosine diphosphate as an intracellular regulator of insulin secretionC G Nichols
Department of Cell Biology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Science 272:1785-7. 1996..Thus, by binding to SUR NBF2 and antagonizing ATP inhibition of KATP++ channels, intracellular MgADP may regulate insulin secretion... - Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter familyC M Gillen
Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Biol Chem 271:16237-44. 1996..These data demonstrate that the KCC1 cDNAs encode a widely expressed K-Cl cotransporter with the characteristics of the K-Cl transporter that has been characterized in red cells... - Ion permeation mechanism of the potassium channelJ Aqvist
Department of Cell and Molecular Biology, Uppsala University, Biomedical Center, Sweden
Nature 404:881-4. 2000..Other putative permeation pathways can be excluded because they would involve states that are too high in energy... - Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channelsM Pusch
Istituto di Cibernetica e Biofisica, Consiglio Nazionale della Ricerche, Via De Marini 6, I 16149 Genova, Italy
Biophys J 78:211-26. 2000..using the two-electrode voltage-clamp and the patch-clamp technique and high extracellular potassium (K) and rubidium (Rb) solutions... - Structural rearrangements underlying K+-channel activation gatingE Perozo
Department of Molecular Physiology and Biological Physics and Center for Structural Biology, University of Virginia Health Sciences Center, Charlottesville, VA 22906 0011, USA
Science 285:73-8. 1999..Although the extracellular residues flanking the selectivity filter remained immobile during gating, small movements were detected at the C-terminal end of the pore helix, with possible implications to the gating mechanism... - The effects of elevated glucose on Na+/K(+)-ATPase of cultured bovine retinal pigment epithelial cells measured by a new nonradioactive rubidium uptake assayJ Y Crider
Molecular Pharmacology Unit, Alcon Laboratories, Inc, Fort Worth, Texas, USA
J Ocul Pharmacol Ther 13:337-52. 1997..The results of the present study suggest that hyperglycemia-induced loss of Na+/K(+)-ATPase function in RPE cells, which responds to aldose reductase inhibitor treatment, contributes to the pathogenesis of diabetic retinopathy... - A new family of K+ transporters from Arabidopsis that are conserved across phylaF J Quintero
Laboratory of Plant Physiology and Biophysics, University of London, Wye College, UK
FEBS Lett 415:206-11. 1997..These and additional results suggest that AtKT1 and AtKT2 belong to a superfamily of cation transporters that have been conserved through evolution... - AtKUP1: an Arabidopsis gene encoding high-affinity potassium transport activityE J Kim
Department of Biology, University of California, San Diego, La Jolla 92093, USA
Plant Cell 10:51-62. 1998..It is proposed that plants contain multiple potassium transporters for high-affinity uptake and that the AtKUP family may provide important components of high- and low-affinity K+ nutrition and uptake into various plant cell types... 
Relative contribution of AtHAK5 and AtAKT1 to K+ uptake in the high-affinity range of concentrationsFrancisco Rubio
Departamento de Nutrición Vegetal, Centro de Edafología y Biología Aplicada del Segura CSIC, Apartado de Correos 164, Murcia 30100, Spain
Physiol Plant 134:598-608. 2008....- Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptorN Inagaki
Division of Molecular Medicine, Chiba University School of Medicine, Japan
Science 270:1166-70. 1995..Gene mapping data show that these two potassium channel subunit genes are clustered on human chromosome 11 at position 11p15.1... - A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distributionMing Zhou
Howard Hughes Medical Institute and Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, New York, NY 10021, USA
J Mol Biol 338:839-46. 2004..The mutation does not affect the conduction of Rb(+). These results can be understood in the context of a conduction mechanism in which a pair of K ions switch between energetically balanced 1,3 and 2,4 configurations... - Expression of KT/KUP genes in Arabidopsis and the role of root hairs in K+ uptakeSung Ju Ahn
Donald Danforth Plant Science Center, 975 North Warson Road, St. Louis, Missouri 63132, USA
Plant Physiol 134:1135-45. 2004..This suggests an important role for root hairs in K(+) uptake. The growth and rubidium (Rb(+)) uptake of two root hair mutants, trh1-1 (tiny root hairs) and rhd6 (root hair defective), were studied to .. - The occupancy of ions in the K+ selectivity filter: charge balance and coupling of ion binding to a protein conformational change underlie high conduction ratesYufeng Zhou
Molecular Neurobiology and Biophysics, Howard Hughes Medical Institute and Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
J Mol Biol 333:965-75. 2003..We conclude that electrostatic balance and coupling of ion binding to a protein conformational change underlie high conduction rates in the setting of high selectivity... - Tight coupling of rubidium conductance and inactivation in human KCNQ1 potassium channelsGuiscard Seebohm
Department of Physiology, University of Utah, Salt Lake City, UT USA, Physiologisches Institut I, , Germany
J Physiol 552:369-78. 2003.... - PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)Brian F X Dowd
Yale University, School of Medicine, Department of Cellular and Molecular Physiology, New Haven, Connecticut 06520 0826, USA
J Biol Chem 278:27347-53. 2003..In cells preloaded with 32Pi, the phosphorylation of PASK, but not DNPASK, coincides with that of NKCC1 and increases 5.5 +/- 0.36-fold in low [Cl]e. These data conclusively link PASK with the phosphorylation and activation of NKCC1... - Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channelsJill Thompson
Department of Pharmacology and Physiology, University of Rochester Medical Center, NY 14642, USA
J Physiol 549:107-20. 2003..These results provide information on the fine-structure of ion interactions with the inner end of the pore in K+ channels... - Cloning and functional characterization of the high-affinity K+ transporter HAK1 of pepperM Angeles Martínez-Cordero
Departamento de Nutrición Vegetal, Centro de Edafología y Biología Aplicada del, Segura CSIC, Apartado de Correos 164, Murcia, 30100, Spain
Plant Mol Biol 56:413-21. 2004..3 and 1.9 microM, respectively. Rb+ uptake was competitively inhibited by micromolar concentrations of NH and Cs+, and by millimolar concentrations of Na+... - Ion binding affinity in the cavity of the KcsA potassium channelYufeng Zhou
Howard Hughes Medical Institute and Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
Biochemistry 43:4978-82. 2004..These results are consistent with a fairly large (more negative than -100 mV) electrostatic potential inside the cavity, and they also imply the presence of a weak nonelectrostatic component to a cation's interaction with the cavity... - External TEA block of shaker K+ channels is coupled to the movement of K+ ions within the selectivity filterJill Thompson
Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA
J Gen Physiol 122:239-46. 2003.... - Tail end of the s6 segment: role in permeation in shaker potassium channelsShinghua Ding
Department of Physiology, Jefferson Medical College, Philadelphia, PA 19107, USA
J Gen Physiol 120:87-97. 2002..These results indicate that S6(T) residues have an influence on the conformation of the open activation gate, reflected in both the stability of the open state and the energy barriers it presents to ions... - A mutation in the Arabidopsis KT2/KUP2 potassium transporter gene affects shoot cell expansionRangasamy P Elumalai
Department of Biology, University of North Carolina at Chapel Hill, Coker Hall, Chapel Hill, NC 27599-3280, USA
Plant Cell 14:119-31. 2002..coli mutant. A P(SHY3)::GUS fusion is expressed in growing portions of the plant. These results suggest that KT2/KUP2/SHY3 mediates K(+)-dependent cell expansion in growing tissues... - The structure of the potassium channel: molecular basis of K+ conduction and selectivityD A Doyle
Laboratory of Molecular Neurobiology and Biophysics and the Howard Hughes Medical Institute, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Science 280:69-77. 1998..The architecture of the pore establishes the physical principles underlying selective K+ conduction... - A thermodynamic study of electroneutral K-Cl cotransport in pH- and volume-clamped low K sheep erythrocytes with normal and low internal magnesiumP K Lauf
Department of Physiology and Biophysics, Wright State University School of Medicine, Dayton, Ohio 45401 0927, USA
J Gen Physiol 108:341-50. 1996..Thus, basal as well as low internal Mg-stimulated net K-Cl cotransport depends on the electrochemical potential gradient of KCl... - Efficiency of rubidium marking in Aedes albopictus (Diptera: Culicidae): preliminary evaluation on persistence of egg labeling, survival, and fecundity of marked femaleRafael Maciel-de-Freitas
, Instituto Oswaldo Cruz-Fiocruz, Av. Brasil 4365, 21040-900 Rio de Janeiro, RJ, Brazil
Mem Inst Oswaldo Cruz 99:823-7. 2004b>Rubidium chloride (RbCl) has been used for the study of vector biology and behavior, although the efficacy of marking, egg production, and survivorship of marked females have been poorly studied... - Protons as substitutes for sodium and potassium in the sodium pump reactionC Polvani
Department of Medicine, McGill University, Montreal, Quebec, Canada
J Biol Chem 263:16757-63. 1988..8. These ATP-dependent cardiac glycoside-sensitive proton movements indicate Na,K-ATPase mediated Na+/H+ exchange in the absence of extracellular K+ as well as H+/K+ exchange in the absence of cytoplasmic Na+... - The multi-ion nature of the pore in Shaker K+ channelsP Perez-Cornejo
University of Rochester Medical School, Department of Physiology, New York 14642
Biophys J 66:1929-38. 1994..91; this increased to 1.3 at 40 mM Cs+. We show that a 4-barrier, 3-site permeation model can simulate these and many of the other known properties of ion permeation in Shaker channels... - A greater stimulation of Na-H antiport in cultured vascular smooth muscle cells by serum from spontaneously hypertensive ratsS Kuriyama
Second Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
Am J Hypertens 4:780-2. 1991..The study suggests that there are humoral factors in SHR serum which elicit the stimulation of the Na-H antiport, leading to the activation of the Na-K pump of VSMC... - Cl secretagogues reduce basolateral K permeability in the rabbit corneal epitheliumO A Candia
Department of Ophthalmology, Mount Sinai School of Medicine, 100th Street and 5th Avenue New York, NY 10029 6574, USA
J Membr Biol 190:197-205. 2002.... - K(+) transport and volume regulatory response by NKCC in resting rat hindlimb skeletal muscleMichael I Lindinger
Dept of Human Biology and Nutritional Sciences, University of Guelph, Ontario, Canada
Cell Physiol Biochem 12:279-92. 2002..The hypertonic perfusate also resulted in temporally associated decreases in net water uptake by muscle. It is concluded that a functional NKCC is present in mammalian skeletal muscle and that it is involved in cell volume regulation... - Metallic content of wines from the Canary Islands (Spain). Application of artificial neural networks to the data analysisSergio Frías
Department of Analytical Chemistry, Nutrition and Food Science, University of La Laguna, Santa Cruz de Tenerife, Spain
Nahrung 46:370-5. 2002..Thus, Lanzarote presented the highest mean content in sodium and lithium and the lowest mean content in rubidium, and La Palma presented the highest mean content in strontium and rubidium... - Molecular analysis of the mechanism of potassium uptake through the TRK1 transporter of Saccharomyces cerevisiaeRosario Haro
, , , Spain
Biochim Biophys Acta 1564:114-22. 2002..ScTRK1 mediates active K(+) uptake. This is not Na(+)-coupled and direct coupling of ScTRK1 to a source of chemical energy seems more probable than K(+)-H(+) cotransport... - Fast network oscillations induced by potassium transients in the rat hippocampus in vitroFiona E N LeBeau
School of Biomedical Sciences, University of Leeds, Leeds LS2 9NQ, UK
J Physiol 542:167-79. 2002Brief pressure ejection of solutions containing potassium, caesium or rubidium ions into stratum radiatum of the CA1 or CA3 regions of the hippocampal slice evoked a fast network oscillation... - Cation transport activity of anion exchanger 1 mutations found in inherited distal renal tubular acidosisStephen Walsh
Laboratoire de Physiologie des Membranes Cellulaires, UMR6548, Centre National de la Recherche Scientifique Université de Nice, Bâtiment de Sciences Naturelles, Nice, France
Am J Physiol Renal Physiol 295:F343-50. 2008..These findings have potential structural and functional implications for AE1, and they indicate that while anion exchange and cation conductance properties are distinct, they can coexist... - Steady-state volumes and metabolism-independent osmotic adaptation in mammalian erythrocytesPeter Bogner
Department of Clinical Chemistry, , Faculty of Medicine, Hungary
Eur Biophys J 31:145-52. 2002..The mobility of lipids within the hydrophobic inner layer of the plasma membrane relates closely to passive K(+) (Rb(+)) uptake, and plays a significant role in regulatory volume changes... - Formation of oriented molecular nanowires on mica surfaceTomoyuki Akutagawa
Research Institute for Electronic Science, Hokkaido University, Sapporo 060-0812, Japan
Proc Natl Acad Sci U S A 99:5028-33. 2002..Such correlation between the nanowires and the substrate surface was also observed when a dilute aqueous rubidium chloride subphase was used... - Difference in substrate specificity divides the yeast alkali-metal-cation/H(+) antiporters into two subfamiliesOlga Kinclová
Department of Membrane Transport, Institute of Physiology CzAcadSci, 14220 Prague 4, Czech Republic
Microbiology 148:1225-32. 2002..rouxii... - A role for the non-phosphorylated form of yeast Snf1: tolerance to toxic cations and activation of potassium transportFrancisco Portillo
Instituto de Investigaciones Biomedicas, Universidad Autónoma de Madrid C S I C, Arturo Duperier 4, 28029 Madrid, Spain
FEBS Lett 579:512-6. 2005..The effect of Snf1 on Trk is probably indirect and could be mediated by the Sip4 transcriptional activator... - Potassium drives daily reversible thallus enlargement in the marine red alga Porphyra leucosticta (Rhodophyta)Luis Escassi
Departamento de Ecologia, Universidad de Malaga, Campus Universitatio de Teatinos s n, 29071 Malaga, Spain
Planta 214:759-66. 2002..The possible effects of the loosening of the cell wall and the internal K+ concentration on the growth of this species are also discussed... - Characterization of potassium transport in wild-type and isogenic yeast strains carrying all combinations of trk1, trk2 and tok1 null mutationsAdam Bertl
Universitat Karlsruhe, Germany
Mol Microbiol 47:767-80. 2003..Based on this finding, we have established a growth-based assay that monitors the in vivo activity of Tok1p... - The link between ion permeation and inactivation gating of Kv4 potassium channelsMohammad Shahidullah
Department of Pathology, Anatomy and Cell Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Biophys J 84:928-41. 2003..By examining possible changes in ionic selectivity and the influence of elevating the external K(+) concentration, additional experiments did not support the presence of C-type inactivation in Kv4 channels... - Sodium and potassium transport in the halophilic yeast Debaryomyces hanseniiJ C González-Hernández
Departamento de Genetica y Biologia Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Apartado 70 242, 04510 Mexico D F, Mexico
Yeast 21:403-12. 2004..It can be concluded that Na(+) in D. hansenii is not excluded but instead, its metabolic systems must be resistant to high salt concentrations... - Alteration of ionic selectivity of a K+ channel by mutation of the H5 regionA J Yool
Department of Molecular and Cellular Physiology, Stanford University Medical Center, California 94305 5426
Nature 349:700-4. 1991..The mutations that substantially altered selectivity had little effect on the gating properties of the channel. We conclude that the H5 region is likely to line the pore of the K+ channel... - The selectivity filter of the tandem pore potassium channel TASK-1 and its pH-sensitivity and ionic selectivityK Yuill
Molecular Physiology Group, Department of Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK
Pflugers Arch 448:63-9. 2004..39+/-0.03 (n=14) in H98D, 0.64+/-0.04 (n=18) in D204H and 0.33+/-0.07 (n=3) in D204N. Thus, the arrangement of ring of residues HDHD appears to optimise both pH sensitivity and ionic selectivity... - Selective binding of monovalent cations to the stacking G-quartet structure formed by guanosine 5'-monophosphate: a solid-state NMR studyAlan Wong
Department of Chemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6
J Am Chem Soc 125:13895-905. 2003..We have demonstrated that solid-state (23)Na and (15)N NMR can be used simultaneously to provide mutually complementary information about competitive binding between Na(+) and NH(4)(+) ions... - Potassium channel, ions, and water: simulation studies based on the high resolution X-ray structure of KcsACarmen Domene
Department of Biochemistry, University of Oxford, Oxford, United Kingdom
Biophys J 85:2787-800. 2003..A preliminary comparison of the use of particle mesh Ewald versus cutoff protocols for the treatment of long-range electrostatics suggests some difference in the kinetics of ion translocation within the filter... - Capillary electrophoresis of anionic analytes in methanol: effect of counter-ions on electrophoretic mobilitySimo P Porras
Laboratory of Analytical Chemistry, Department of Chemistry, University of Helsinki, Helsinki, Finland
Electrophoresis 23:367-74. 2002..Exceptions are some di- and trihydroxybenzoates. The mobilities in methanol and in water with the same counter-ion (Na+) at a given ionic concentration show very low correlation... - Effects of palytoxin on cation occlusion and phosphorylation of the (Na+,K+)-ATPaseM T Tosteson
Laboratory for Membrane Transport, Department of Cell Biology, Harvard Medical School, One Kendall Square, Building 600 Third Floor, Cambridge, MA 02139, USA
J Membr Biol 192:181-9. 2003.... - Effect of acute hyperglycemia on erythrocyte membrane ion transport in offspring of hypertensive parentsGabriela Suchankova
Diabetes Center, Institute for Clinical and Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic
J Hypertens 21:1325-30. 2003..The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyperglycemia on RBC ion transport in the offspring of hypertensive parents (OHP) and healthy controls (C)... - The TRK1 potassium transporter is the critical effector for killing of Candida albicans by the cationic protein, Histatin 5Didi Baev
Department of Oral Biology, School of Dental Medicine, State University of New York, Buffalo, NY 14214, USA
J Biol Chem 279:55060-72. 2004..albicans... - The schiff base of gossypol with 3,6,9,12,15,18,21,24-octaoxa-pentacosylamine complexes and monovalent cations studied by electrospray ionization-mass spectrometry, (1)H nuclear magnetic resonance, Fourier transform infrared, as well as PM5 semiempirical Piotr Przybylski
Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, 60-780 Poznan, Poland
Biopolymers 74:273-86. 2004..The two protons are localized on the N atoms of the Schiff base, and the complex exists in the imine-imine tautomeric form. The structures of the complexes are calculated by PM5 semiempirical methods and discussed... - Intracellular Na concentration and Rb uptake in proximal convoluted tubule cells and abundance of Na/K-ATPase alpha1-subunit in NHE3-/- miceFranz X Beck
Physiologisches Institut der Universitat, Pettenkoferstrasse 12, 80336, Munich, Germany
Pflugers Arch 446:100-5. 2003..There were no significant changes of cell Na concentration and Rb uptake in distal convoluted tubule, connecting tubule, principal and intercalated cells... - [Potassium transport in erythrocytes from patients with gentamicin intolerance]F V Toropova
Institute of Cytology RAS, St. Petersburg
Tsitologiia 44:1194-8. 2002A study was made of rubidium (potassium analog) influxes via ouabain-sensitive Na/K pump, bumetanide-sensitive cotransport and resistant to ouabain bumetanide membrane ion pathways and of the intracellular potassium and sodium contents in .. - K(+) transport in Malpighian tubules of Tenebrio molitor L: a study of electrochemical gradients and basal K(+) uptake mechanismsU I M Wiehart
Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa
J Exp Biol 206:949-57. 2003..b>Rubidium, a 'permeant' potassium substitute, caused a hyperpolarization of V(bl), indicating the specificity of K(+) .. - Sodium fluxes through nonselective cation channels in the plasma membrane of protoplasts from Arabidopsis rootsVadim Demidchik
Department of Plant Sciences, University of Cambridge, Cambridge, CB2 3EA United Kingdom
Plant Physiol 128:379-87. 2002..It is suggested that NSCCs present a distinct group of plant ion channels, mediating toxic Na(+) influx to the cell and probably having other important roles in physiological processes of plants... - L-rhamnulose 1-phosphate aldolase from Escherichia coli. Crystallization and propertiesT H Chiu
Biochemistry 8:98-108. 1969 - Fusicoccin- and IAA-induced elongation growth share the same pattern of K+ dependenceK Tode
, Ohnhorststr. 18, D-22609 Hamburg, Germany
J Exp Bot 52:251-5. 2001..However, TEA abolished this apparently K+ independent FC-induced growth. It is concluded that FC-induced growth, like auxin-induced growth, requires K+ uptake through K+ channels... - Analysis of the monovalent ion fluxes in U937 cells under the balanced ion distribution: recognition of ion transporters responsible for changes in cell ion and water balance during apoptosisA A Vereninov
Institute of Cytology RAS, Tikhoretsky Avenue 4, 194064 St Petersburg, Russia
Cell Biol Int 31:382-93. 2007.... - Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experimentsV Tereshko
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
Nucleic Acids Res 29:1208-15. 2001..Conversely, high resolution of the data alone does not necessarily allow differentiation between water and partially ordered metal ions, as demonstrated with the crystal structure of a DNA duplex determined to a resolution of 0.6 A... - Rubidium chloride tolerant callus cultures of rice (Oryza sativa L.) accumulate more potassium and cross tolerate to other saltsR Naga Amrutha
Department of Genetics, Osmania University, Hyderabad 500 007, India
Plant Cell Rep 26:1647-62. 2007..were established in Murashige and Skoog's (MS) medium containing lethal concentrations (50 mM) of rubidium chloride (RbCl) as a selective agent... - Influence of permeating ions on Kv1.5 channel block by nifedipineS Lin
Department of Physiology, University of British Columbia, 2146 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada
Am J Physiol Heart Circ Physiol 280:H1160-72. 2001..This is consistent with the conclusion that nifedipine block and C-type inactivation in the Kv1.5 channel can coexist but are mediated by distinct mechanisms coordinated by outer pore conformation... - Atomic structure of a Na+- and K+-conducting channelNing Shi
Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9040, USA
Nature 440:570-4. 2006..We conclude that the sequence of the NaK selectivity filter resembles that of a cyclic nucleotide-gated channel and its structure may represent that of a cyclic nucleotide-gated channel pore... - Comparison of K-Cl cotransport expression in high and low K dog erythrocytesHideharu Ochiai
Research Institute of Biosciences, Azabu University, Sagamihara, Kanagawa, Japan
Exp Anim 55:57-63. 2006..These results suggest that the difference in cotransport activity was not caused by the amount of K-Cl cotransport protein but by a difference in the regulation system, which is susceptible to oxidant... - Apparent intermediate K conductance channel hyposmotic activation in human lens epithelial cellsPeter K Lauf
Cell Biophysics Group, 054 Biological Sciences Bldg, Wright State Univ Boonshoft School of Medicine, Dayton, OH 45435, USA
Am J Physiol Cell Physiol 294:C820-32. 2008..1 channels, aside of the KCC1, KCC2, KCC3 and KCC4 isoforms. Apparently, IK channels, possibly in parallel with volume-sensitive outwardly rectifying Cl channels, effect regulatory volume decrease in LECs... - Entrance port for Na(+) and K(+) ions on Na(+),K(+)-ATPase in the cytoplasmic loop between trans-membrane segments M6 and M7 of the alpha subunit. Proximity Of the cytoplasmic segment of the beta subunitA Shainskaya
Department of Biological Chemistry, Weizmann Institute of Science, 76100 Rehovot, Israel and Department of Biology, University of Konstanz, D-78434 Konstanz, Germany
J Biol Chem 275:2019-28. 2000..2) Na(+) ions specifically protect the 16-kDa fragment against this chymotryptic cleavage... - 7Li-NMR and FTIR studies of lithium, potassium, rubidium, and cesium complexes with ionophore lasalocid in solutionR Pankiewicz
Department of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, , Poland
Biopolymers 62:173-82. 2001Lasalocid metal salts were combined with 1 : 1 lithium and 2:2 potassium, rubidium, and cesium to form complexes... - The yeast potassium transporter TRK2 is able to substitute for TRK1 in its biological function under low K and low pH conditionsBertha Michel
Depto de Genética Molecular, Instituto de Fisiologia Celular, UNAM, Circuito exterior s n, Ciudad Universitaria, D F 04510, Mexico
Yeast 23:581-9. 2006..Taken together, these results indicate that TRK2 encodes a functional K+ transporter that, under our experimental conditions, displays distinctive kinetic characteristics... - Plasma-membrane Cnh1 Na+/H+ antiporter regulates potassium homeostasis in Candida albicansOlga Kinclova-Zimmermannova
Department of Membrane Transport, Institute of Physiology AS CR, v v i, Videnska 1083, 142 20 Prague 4 Krc, Czech Republic
Microbiology 153:2603-12. 2007..The potassium and rubidium tolerance of a cnh1 homozygous mutant was fully restored by reintegration of CNH1 into the genome... - A trapped intracellular cation modulates K+ channel recovery from slow inactivationEvan C Ray
Department of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA
J Gen Physiol 128:203-17. 2006..We propose that the rate of recovery from slow inactivation is determined by the ability of entrapped cations to move into a binding site in the channel's selectivity filter, and refilling of this site is required for recovery... - Characterization of glial cell K-Cl cotransportKenneth B E Gagnon
Cell Biophysics Group, Wright State University, Dayton, OH 4543, USA
Cell Physiol Biochem 20:121-30. 2007..The molecular mechanism of K-Cl cotransport (KCC) consists of at least 4 isoforms, KCC 1, 2, 3, and 4 which, in multiple combinations, exist in most cells, including erythrocytes and neuronal cells... - Mutational effects on conformational changes of the dephospho- and phospho-forms of the Na+,K+-ATPaseM Toustrup-Jensen
Department of Physiology, University of Aarhus, , DK-8000 Aarhus C, Denmark
Biochemistry 40:5521-32. 2001.... - The KCl cotransporter isoform KCC3 can play an important role in cell growth regulationM R Shen
University Laboratory of Physiology, Parks Road, Oxford, OX1 3PT, United Kingdom
Proc Natl Acad Sci U S A 98:14714-9. 2001..Tumor necrotic factor-alpha down-regulates KCC3 expression and causes growth arrest. These data indicate that KCC3 is an important KCC isoform that may be involved in cell proliferation... - Regulation of potassium transport in human lens epithelial cellsPeter K Lauf
Cell Biophysics Group, Wright State University School of Medicine, Dayton, OH 45435, USA
Exp Eye Res 82:55-64. 2006..The data suggest at least partial inverse regulation of KCC and NKCC in HLE-B3 cells by signaling cascades involving serine, threonine and tyrosine phosphorylation/dephosphorylation equilibria... - Inhibition of delayed rectifier K(+)-current by levcromakalim in single intestinal smooth muscle cells: effects of cations and dependence on K(+)-fluxD McHugh
Department of Pharmacology, University of Leeds
Br J Pharmacol 114:391-9. 1995.... - Gating properties of inward-rectifier potassium channels: effects of permeant ionsH Choe
Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
J Membr Biol 184:81-9. 2001..The patterns of voltage-dependence of closed-state lifetimes, which are specific for different ions, can be explained by variations in the rate at which the bound ions leave the pore toward the inside or the outside of the cell... - Multiple transport functions of a red blood cell anion exchanger, tAE1: its role in cell volume regulationH Guizouarn
Laboratoire de Physiologie des Membranes Cellulaires, UMR 6078, , , 284 chemin du Lazaret, 06230 Villefranche-sur-Mer, France
J Physiol 535:497-506. 2001..6. tAE1 illustrates the ability of a specific transport system to be a multifunctional protein exhibiting other transport functions when submitted to regulation... - Separation of P/C- and U-type inactivation pathways in Kv1.5 potassium channelsHarley T Kurata
Department of Cellular and Physiological Sciences, University of British Columbia, 2146 Health Sciences Mall, Vancouver B.C. V6T 1Z3, Canada
J Physiol 568:31-46. 2005..Collectively, these data distinguish between open-state and closed-state inactivation, and suggest the presence of multiple possible mechanisms of inactivation coexisting in Kv1 channels... - High temperature NMR study of the local structure of molten LaF3-AF (A = Li, Na, K and Rb) mixturesAnne Laure Rollet
Centre de Recherche sur les Matériaux à Haute Température CNRS, Orleans cedex 2, France
Phys Chem Chem Phys 10:3222-8. 2008..The coordination number of lanthanum is decreased versus AF amount all the more since the alkali atomic number is high. Moreover, the more polarisable the alkali, the less bridging fluorines between the LaF(x) units... - Ionic selectivity of native ATP-activated (P2X) receptor channels in dissociated neurones from rat parasympathetic gangliaD M Liu
School of Biomedical Sciences, Department of Physiology and Pharmacology, University of Queensland, Brisbane, Queensland 4072, Australia
J Physiol 534:423-35. 2001..The relative permeabilities of the monovalent inoganic and organic cations tested are similar to those reported previously for cloned rat P2X(2) receptors expressed in mammalian cells... - NhaK, a novel monovalent cation/H+ antiporter of Bacillus subtilisMakoto Fujisawa
Graduate School of Life Sciences, Toyo University, 1 1 1 Izumino, Itakura machi, Oura gun, Gunma, 374 0193, Japan
Arch Microbiol 183:411-20. 2005..In addition, the expression level was significantly increased in the presence of added K+ and Na+... - Low-affinity potassium uptake by Saccharomyces cerevisiae is mediated by NSC1, a calcium-blocked non-specific cation channelHermann Bihler
Botanisches Institut, Lehrstuhl I, Universitat Karlsruhe, Germany
Biochim Biophys Acta 1558:109-18. 2002..Growth inhibition by lithium ions is probably a toxic effect, whereas growth inhibition by ammonium ions probably results from competitive inhibition, i.e. displacement of intracellular potassium by entering ammonium... - Future direction of renal positron emission tomographyZsolt Szabo
Division of Nuclear Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Semin Nucl Med 36:36-50. 2006..may be even more useful in a clinical setting are those that either can be obtained from radionuclide generators (rubidium-82, copper-62) or have a sufficiently long half-life for transportation (fluorine-18)... - Proceedings of the 13th Conference on Liquid and Amorphous Metals (LAM13) (Ekaterinburg, Russia, 8-14 July 2007)Pjotr Popel
Ural State Pedagogical University
J Phys Condens Matter 20:110301. 2008 - Ionic charge, radius, and potential control root/soil concentration ratios of fifty cationic elements in the organic horizon of a beech (Fagus sylvatica) forest podzolGermund Tyler
Department of Ecology, Soil Plant Research, Ecology Building, SE 223 62 Lund, Sweden
Sci Total Environ 329:231-9. 2004..hafnium, mercury, holmium, indium, lanthanum, lithium, lutetium, niobium, neodymium, nickel, lead, praseodymium, rubidium, scandium, samarium, tin, terbium, thorium, titanium, thallium, thulium, uranium, vanadium, yttrium, ytterbium, .. - Persistent organic pollutants and metals in the freshwater biota of the Canadian Subarctic and Arctic: an overviewMarlene S Evans
National Water Research Institute, Environment Canada, 11 Innovation Boulevard, Saskatoon, SK, Canada S7N 3H5
Sci Total Environ 351:94-147. 2005..Less research has been conducted on other metals but some, such as rubidium, show pronounced variations in concentration that may be related to geological influences... - The effects of rubidium, caesium and quinine on 5-HT-mediated behaviour in rat and mouse--3. QuinineH Wang
MRC Unit, Radcliffe Infirmary, Oxford, U K
Neuropharmacology 31:425-31. 1992..the basis of these findings, together with those in the preceding two papers, it is suggested that the effects of rubidium, caesium and quinine, to enhance differentially various aspects of 5-HT function are mediated by actions on 5-HT-.. - Rabbit corneal hydration and the bicarbonate pumpJ S Swan
Department of Pharmacology, University of Bristol, School of Medical Sciences, Bristol, BS8 1TD, UK
J Membr Biol 201:33-40. 2004..04 +/- 0.03 micromoles x cm(-2) x h(-1)). Similar magnitude fluxes for both bicarbonate and rubidium were found with open-circuit preparations... - Efflux of rubidium in rat cortical synaptosomes is blocked by sigma and dextromethorphan binding site ligandsE J Fletcher
Department of Basic Veterinary Sciences, Royal Veterinary College, London, U K
Neuropharmacology 28:661-6. 1989Large concentrations of potassium were used to stimulate the release of rubidium-86 from preloaded cortical synaptosomes, so that the pharmacological sensitivity of this efflux could be examined... - Effect of a counterion on the glass transition temperature (T(g)') during lyophilization of ganciclovir salt formsLokesh Kumar
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research NIPER, SAS Nagar, Mohali, Punjab 160 062, India
Mol Pharm 8:309-14. 2011..Salt forms of ganciclovir, namely, sodium, potassium, rubidium, and cesium salts, were prepared by an in situ technique and analyzed by modulated differential scanning .. - The distribution patterns of trace elements in the brain and erythrocytes in a rat experimental model of iodine deficiencyN Q Liu
Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics, Academia Sinica, Beijing, People s Republic of China
Brain Res Bull 55:309-12. 2001..Br] in brain tissue samples; potassium [K], calcium [Ca], manganese [Mn], iron [Fe], copper [Cu], zinc [Zn], rubidium [Rb], and lead [Pb] in erythrocytes) after supplementing the rats with I and/or Se... - The interrelationship of cesium, intracellular sodium activity, and pacemaker potential in cardiac Purkinje fibersG Iacono
Department of Physiology, State University of New York, Brooklyn 11203
Can J Physiol Pharmacol 68:1236-46. 1990..6%, p less than 0.05) and transiently hyperpolarized (+2.1%). Rubidium (2 mM) decreased aiNa and resting potential in Purkinje fibers and in myocardial fibers and also decreased .. - Effects of rubidium on responses to potassium channel openers in rat isolated aortaI A Greenwood
Department of Physiological Sciences, University of Manchester
Br J Pharmacol 109:925-32. 19931. In a physiological salt solution (PSS) in which potassium (K) was replaced by rubidium (Rb), segments of rat aorta precontracted with 20 mM RbCl were fully relaxed by K-channel openers with an order of potency levcromakalim > .. - Accumulation of potassium, rubidium and caesium (133Cs and 137Cs in various fractions of soil and fungi in a Swedish forestM Vinichuk
Department of Soil and Environment, Swedish University of Agricultural Sciences, P O Box 7014, SE 750 07, Uppsala, Sweden
Sci Total Environ 408:2543-8. 2010..that fungal sporocarps efficiently accumulate radiocaesium ((137)Cs), as well as the alkali metals potassium (K), rubidium (Rb) and caesium (Cs). The fungi then enhance uptake of these elements into host plants... - Altered electrolyte handling of the choroid plexus in rats with glycerol-induced acute renal failureAtsuko Ishikawa
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700 8530, Japan
Biopharm Drug Dispos 31:455-63. 2010..handling of the choroid plexus was investigated in rats with acute renal failure (ARF) using lithium and rubidium as surrogate markers for sodium and potassium, respectively... - Bile salt-induced calcium fluxes in artificial phospholipid vesiclesD G Oelberg
University of Texas Medical School, Department of Pediatrics, Houston 77225
Biochim Biophys Acta 937:289-99. 1988..Comparison of radiolabelled calcium uptake with radiolabelled sodium or radiolabelled rubidium uptake indicated that bile salt-dependent calcium uptake was 60-140-times greater than bile salt-dependent uptake ..
Research Grants
- PATHOGENESIS OF HERPETIC KERATITISWILLIAM O BRIEN; Fiscal Year: 2002..Pump function will be measured by rubidium uptake and enzyme activity by phosphate release from ATP...
- Chronic Nicotine Effects on Receptor SubtypesDavid C Perry; Fiscal Year: 2010..of chronic nicotine exposure on expression (using autoradiography and immunoprecipitation) and function (using rubidium efflux and neurotransmitter release) of nAChR subtypes, alteration of neuronal morphology (measuring dendritic ..
- Chronic Nicotine Effects on Receptor SubtypesDavid Perry; Fiscal Year: 2009..of chronic nicotine exposure on expression (using autoradiography and immunoprecipitation) and function (using rubidium efflux and neurotransmitter release) of nAChR subtypes, alteration of neuronal morphology (measuring dendritic ..
- Mechanisms of serum electrolyte effects on block of HERGAlan Miller; Fiscal Year: 2006..channels or mutant HERG channels to study the mechanisms by which the extracellular monovalent cations potassium, rubidium, and cesium and the divalent cations calcium and magnesium alter block of HERG by a number of different compounds ..
- Biochemistry of Normal & Abnormal Variants of Factors IXS Bajaj; Fiscal Year: 2006..site, we will prepare EGF2-protease segment of FIXa and crystallize it in the presence of (a) sodium and (b) rubidium and determine its structure...
- Atomic BiomagnetometerTHAD WALKER; Fiscal Year: 2005..The specific aims are: 1. To build a optical magnetometer/gradiometer that utilizes rubidium atoms and achieves a magnetic field sensitivity 10A-14 T/(Hz)A1/2. 2...
- Atomic BiomagnetometerTHAD WALKER; Fiscal Year: 2006..The specific aims are: 1. To build a optical magnetometer/gradiometer that utilizes rubidium atoms and achieves a magnetic field sensitivity 10A-14 T/(Hz)A1/2. 2...
- Brain K+ Dynamics, BBB Breakdown & Hemorrhagic Transformation in Ischemic StrokeStephen Jones; Fiscal Year: 2009..We will use K/Rb substitution MRI to observe this [K+]brfall. Rubidium-87, but not K, can be effectively observed with MRI,acts as a congener of K+, and can be substituted for K (18%) ..
- Brain K+ Dynamics, BBB Breakdown & Hemorrhagic Transformation in Ischemic StrokeStephen Jones; Fiscal Year: 2009..We will use K/Rb substitution MRI to observe this [K+]brfall. Rubidium-87, but not K, can be effectively observed with MRI, acts as a congener of K+, and can be substituted for K (18%) ..
- Brain K+ Dynamics, BBB Breakdown & Hemorrhagic Transformation in Ischemic StrokeStephen Jones; Fiscal Year: 2007..We will use K/Rb substitution MRI to observe this [K+]brfall. Rubidium-87, but not K, can be effectively observed with MRI, acts as a congener of K+, and can be substituted for K (18%) ..
- SHORT TERM REGULATION OF THE NA+ PUMPCarlos Pedemonte; Fiscal Year: 2001..and amino-terminus mutants of the rodent alpha subunit expressed in OK cells and will involve measurements of rubidium, ATPase activities and changes in intracellular sodium concentrations. The second aim has two parts...
- Third Symposium Cell Volume & Signalling RegulationPETER LAUF; Fiscal Year: 2003..This meeting's success on U.S. soil will foster continuation of gathering of high-caliber scientists at subsequent international meetings ..
- Proteomics of M-L antigens modulating cation transportPETER LAUF; Fiscal Year: 2004....
- From Clinic to Bench & Back: Clinical Biodetective Training (RMI)Mark Milanick; Fiscal Year: 2007..e., approaches that can be used in family practice settings, by nurses and nurse practitioners, and by patients for selfmonitoring) in situations where the patient and clinician are not necessarily in a hospital setting. ..