mebendazole

Summary

Summary: A nematocide in humans and animals. It acts by interfering with the carbohydrate metabolism and associated energy production of the parasite.

Top Publications

  1. ncbi Albendazole, mebendazole and praziquantel. Review of non-clinical toxicity and pharmacokinetics
    A D Dayan
    Parasitic Diseases and Vector Control PVC, Communicable Diseases Control, Prevention and Eradication CPE, World Health Organization, CH 1211 Geneva 27, Switzerland
    Acta Trop 86:141-59. 2003
  2. ncbi Spinal hydatidosis
    Antonio Herrera
    Service of Orthopaedic and Trauma Surgery, Miguel Servet University Hospital, Zaragoza, Spain
    Spine (Phila Pa 1976) 30:2439-44. 2005
  3. ncbi Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, PO Box, CH 4002 Basel, Switzerland
    JAMA 299:1937-48. 2008
  4. pmc Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial
    Peter Steinmann
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS ONE 6:e25003. 2011
  5. ncbi Albendazole and mebendazole administered alone or in combination with ivermectin against Trichuris trichiura: a randomized controlled trial
    Stefanie Knopp
    Departments of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Clin Infect Dis 51:1420-8. 2010
  6. pmc Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR
    Phonepasong Ayé Soukhathammavong
    National Institute of Public Health, Ministry of Health, Vientiane, Lao People s Democratic Republic
    PLoS Negl Trop Dis 6:e1417. 2012
  7. ncbi Treatment of eosinophilic meningitis with a combination of prednisolone and mebendazole
    Verajit Chotmongkol
    Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Am J Trop Med Hyg 74:1122-4. 2006
  8. ncbi Coverage and costs of a school deworming programme in 2007 targeting all primary schools in Lao PDR
    Bounlay Phommasack
    National School Health Taskforce, Department of Hygiene and Prevention, Ministry of Health, Simuang Road, Vientiane Capital, Lao PDR
    Trans R Soc Trop Med Hyg 102:1201-6. 2008
  9. pmc Efficacy of different albendazole and mebendazole regimens against heavy-intensity Trichuris trichiura infections in school children, Jimma Town, Ethiopia
    Z Mekonnen
    Department of Medical Laboratory Sciences and Pathology, College of Public Health and Medical Sciences, Jimma University, Ethiopia
    Pathog Glob Health 107:207-9. 2013
  10. pmc Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme
    Ren Yuan Bai
    Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Neuro Oncol 13:974-82. 2011

Detail Information

Publications235 found, 100 shown here

  1. ncbi Albendazole, mebendazole and praziquantel. Review of non-clinical toxicity and pharmacokinetics
    A D Dayan
    Parasitic Diseases and Vector Control PVC, Communicable Diseases Control, Prevention and Eradication CPE, World Health Organization, CH 1211 Geneva 27, Switzerland
    Acta Trop 86:141-59. 2003
    The pharmacokinetics and toxicity of albendazole, mebendazole and praziquantel are extensively reviewed, drawing on original published work and reviews in the open scientific literature and on assessments by international agencies and ..
  2. ncbi Spinal hydatidosis
    Antonio Herrera
    Service of Orthopaedic and Trauma Surgery, Miguel Servet University Hospital, Zaragoza, Spain
    Spine (Phila Pa 1976) 30:2439-44. 2005
    ..Retrospective study...
  3. ncbi Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis
    Jennifer Keiser
    Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, PO Box, CH 4002 Basel, Switzerland
    JAMA 299:1937-48. 2008
    ..Preventive chemotherapy is the mainstay of control, but only 4 drugs are available: albendazole, mebendazole, levamisole, and pyrantel pamoate.
  4. pmc Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial
    Peter Steinmann
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS ONE 6:e25003. 2011
    ..helminth (STH) infections currently relies on the large-scale administration of single-dose oral albendazole or mebendazole. However, these treatment regimens have limited efficacy against hookworm and Trichuris trichiura in terms of ..
  5. ncbi Albendazole and mebendazole administered alone or in combination with ivermectin against Trichuris trichiura: a randomized controlled trial
    Stefanie Knopp
    Departments of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
    Clin Infect Dis 51:1420-8. 2010
    Single-dose albendazole and mebendazole show limited efficacy in the treatment of trichuriasis...
  6. pmc Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR
    Phonepasong Ayé Soukhathammavong
    National Institute of Public Health, Ministry of Health, Vientiane, Lao People s Democratic Republic
    PLoS Negl Trop Dis 6:e1417. 2012
    Albendazole and mebendazole are increasingly deployed for preventive chemotherapy targeting soil-transmitted helminth (STH) infections...
  7. ncbi Treatment of eosinophilic meningitis with a combination of prednisolone and mebendazole
    Verajit Chotmongkol
    Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Am J Trop Med Hyg 74:1122-4. 2006
    To study the efficacy of the combination of prednisolone and mebendazole for the treatment of eosinophilic meningitis, we conducted a pilot study among Thai patients with eosinophilic meningitis...
  8. ncbi Coverage and costs of a school deworming programme in 2007 targeting all primary schools in Lao PDR
    Bounlay Phommasack
    National School Health Taskforce, Department of Hygiene and Prevention, Ministry of Health, Simuang Road, Vientiane Capital, Lao PDR
    Trans R Soc Trop Med Hyg 102:1201-6. 2008
    ..The Lao Government has addressed the problem by organizing regular anthelminthic chemotherapy with mebendazole 500mg for school and pre-school children in conjunction with health education activities incorporated into the ..
  9. pmc Efficacy of different albendazole and mebendazole regimens against heavy-intensity Trichuris trichiura infections in school children, Jimma Town, Ethiopia
    Z Mekonnen
    Department of Medical Laboratory Sciences and Pathology, College of Public Health and Medical Sciences, Jimma University, Ethiopia
    Pathog Glob Health 107:207-9. 2013
    ..Therefore, the objective of this study was to determine the efficacy of albendazole (ALB) and mebendazole (MBZ) administered randomly for 1 (ALB×1 and MBZ×1) or 2 days (ALB×2 and MBZ×2) to 385 school children with ..
  10. pmc Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme
    Ren Yuan Bai
    Ludwig Collaborative Laboratory, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Neuro Oncol 13:974-82. 2011
    ..Subsequent in vitro and in vivo experiments with benzimidazoles identified mebendazole as the more promising drug for GBM therapy...
  11. ncbi The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda
    Harriet Namwanje
    Vector Control Division, Ministry of Health, P O Box 1661, Kampala, Uganda
    Parasitology 138:1586-92. 2011
    ..In addition, although mebendazole has been extensively used together with praziquantel against infections with schistosomiasis and soil-..
  12. ncbi Efficacy of single and double doses of albendazole and mebendazole alone and in combination in the treatment of Trichuris trichiura in school-age children in Uganda
    Harriet Namwanje
    Vector Control Division, Ministry of Health, P O Box 1661, Kampala, Uganda
    Trans R Soc Trop Med Hyg 105:586-90. 2011
    ..to compare the efficacies of single and double doses of a combination of 400mg albendazole (ALB) and 500mg mebendazole (MBZ) with those of single and double doses of each drug given alone in the treatment of Trichuris trichiura...
  13. ncbi Hepatic and extra-hepatic metabolic pathways involved in flubendazole biotransformation in sheep
    Laura Maté
    Laboratorio de Farmacologia, Departamento de Fisiopatologia, Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires, 7000 Tandil, Argentina
    Biochem Pharmacol 76:773-83. 2008
    ..CBR substrates such as menadione and mebendazole (a non-fluoride analogue of FLBZ), inhibited this liver microsomal enzymatic reaction, which may confirm the ..
  14. ncbi Comparison of the efficacy of mebendazole, albendazole and pyrantel in treatment of human hookworm infections in the southern region of Mali, West Africa
    M Sacko
    Institut National de Recherche en Sante Publique INRSP, Service de Parasitologie, Bamako Coura, Mali
    Trans R Soc Trop Med Hyg 93:195-203. 1999
    A randomized, placebo-controlled trial of the efficacy of pyrantel (single dose 12.5 mg/kg bodyweight), mebendazole (single 500 mg dose) and albendazole (single 400 mg dose) in the treatment of hookworm infections (Necator americanus) ..
  15. ncbi Quality evaluation of generic drugs by dissolution test: changing the USP dissolution medium to distinguish between active and non-active mebendazole polymorphs
    Erna Swanepoel
    Research Institute for Industrial Pharmacy, Potchefstroom University for CHE, Potchefstroom, South Africa
    Eur J Pharm Biopharm 55:345-9. 2003
    b>Mebendazole is practically insoluble in water and studies of its polymorphism has led to the identification and characterization of three polymorphic forms (A, B, C) displaying solubility and therapeutic differences that show that ..
  16. ncbi Comparative effect of mebendazole, albendazole, tribendimidine, and praziquantel in treatment of rats infected with Clonorchis sinensis
    Shu Hua Xiao
    National Institute of Parasitic Diseases, Chinese Center for Disease, Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Malaria, Schistosomiasis, and Filariasis, Shanghai 200025, People s Republic of China
    Parasitol Res 108:723-30. 2011
    The aim of the study is to understand the anti-Clonorchis sinensis properties of mebendazole and albendazole, and compare to praziquantel and tribendimidine...
  17. ncbi Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children
    Cesar E Davila-Gutierrez
    Unidad de Investigacion en Epidemiologia Clinica, Hospital General de Zona y Medicina Familiar No Uno, Dr Leonel Ramírez Garcia, Instituto Mexicano del Seguro Social, Colima, Mexico
    Am J Trop Med Hyg 66:251-4. 2002
    ..The present study was carried out to evaluate the effectiveness of nitazoxanide compared with that of quinfamide, mebendazole, or both in the treatment of intestinal protozoa and helminthic infections...
  18. ncbi The effects of fenbendazole, flubendazole and mebendazole on activities of hepatic cytochromes P450 in pig
    V Baliharová
    Faculty of Pharmacy, Charles University, Heyrovskeho 1203, CZ 50005 Hradec Kralove, Czech Republic
    J Vet Pharmacol Ther 27:85-90. 2004
    Fenbendazole (FBZ), flubendazole (FLBZ) and mebendazole (MBZ) are benzimidazole anthelmintics widely used in veterinary medicine...
  19. ncbi A comparative study of albendazole and mebendazole-induced, time-dependent oxidative stress
    Claudriana Locatelli
    Departmentos de Ecologia e Zoologia, Universidade Federal de Santa Catarina, Florianopolis, Brazil
    Redox Rep 9:89-95. 2004
    Albendazole (ABZ) and mebendazole (MBZ) are two benzimidazole-derived drugs that show remarkable antihelmintic activity and are widely used in the treatment and control of helminths...
  20. ncbi Pharmacokinetic evaluation of guar gum-based colon-targeted drug delivery systems of mebendazole in healthy volunteers
    Y S R Krishnaiah
    Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam, 530 003, India
    J Control Release 88:95-103. 2003
    The pharmacokinetic evaluation of guar gum-based colon-targeted tablets of mebendazole against an immediate release tablet was carried out in human volunteers...
  21. ncbi Variable-temperature X-ray powder diffraction analysis of the crystal transformation of the pharmaceutically preferred polymorph C of mebendazole
    Melgardt M de Villiers
    School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana 71209, USA
    J Pharm Biomed Anal 38:435-41. 2005
    b>Mebendazole is a common benzimidazole anthelmintic that is water insoluble. It is reported to exist in three different polymorphic forms in the solid state, i.e. polymorph A, B and C...
  22. ncbi Development of colon targeted drug delivery systems for mebendazole
    Y S Krishnaiah
    Pharmaceutical Technology Division, Department of Pharmaceutical Sciences, College of Engineering, Andhra University, Visakhapatnam 530 003, India
    J Control Release 77:87-95. 2001
    The objective of the present study is to develop colon targeted drug delivery systems for mebendazole using guar gum as a carrier...
  23. ncbi Study of the reproductive capacity of Trichinella spiralis recovered from experimentally infected mice under-dosed with albendazole or mebendazole
    J L De-La-Rosa
    Laboratory of Tissular Helminthes, Institute of Epidemiological Diagnostic and Reference Ministry of Health Mexico City, 11340 Mexico
    Trop Biomed 24:93-7. 2007
    ..of Trichinella spiralis recovered from experimentally infected mice under-dosed with albendazole (ALB) or mebendazole (MEB) was studied. Different groups of male C57/BL mice were infected with 10 +/- 0...
  24. ncbi Efficacy of thiabendazole, mebendazole, levamisole and ivermectin against gullet worm, Gongylonema pulchrum: in vitro and in vivo studies
    Noboru Kudo
    Department of Veterinary Parasitology, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Aomori, Japan
    Vet Parasitol 151:46-52. 2008
    In vitro and in vivo studies were conducted to evaluate the effects of thiabendazole, mebendazole, levamisole and ivermectin against Gongylonema pulchrum...
  25. ncbi Characterization of polymorph transformations that decrease the stability of tablets containing the WHO essential drug mebendazole
    Marius Brits
    Research Institute for Industrial Pharmacy and CENQAM, North West University, Potchefstroom 2520, South Africa
    J Pharm Sci 99:1138-51. 2010
    This study investigated the influence of moisture and heat on the stability of mebendazole polymorph C in tablets...
  26. ncbi Antiproliferative effect of benzimidazole anthelmintics albendazole, ricobendazole, and flubendazole in intestinal cancer cell lines
    Vera Králová
    Department of Medical Biology and Genetics, Faculty of Medicine, Charles University in Prague, Hradec Kralove, Czech Republic
    Anticancer Drugs 24:911-9. 2013
    ..The anthelmintic benzimidazole drugs ABZ and FLU show a significant cytostatic effect and potentiate the efficacy of PTX in intestinal cancer cells...
  27. ncbi Determination of the minmum effective dosages of praziquantel, albendazole, and mebendazole against Clonorchis sinensis infection in rats
    Ping Chin Fan
    Institute of Tropical Medicine and Department of Parasitology, National Yangming University, Taipei, Taiwan
    Kaohsiung J Med Sci 21:448-51. 2005
    In order to determine the minimum effective dosages of praziquantel, albendazole, and mebendazole against Clonorchis sinensis infection in Sprague-Dawley rats, each rat was infected with 30 metacercariae and treated with one of three ..
  28. ncbi Treatment coverage survey after a school-based mass distribution of mebendazole: Kampot Province, Cambodia
    Nicholas Chesnaye
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States
    Acta Trop 118:21-6. 2011
    ..helminth (STH) infections in school age children (SAC, 6-14 years old), Children Without Worms donates mebendazole to 8 countries with high prevalence of STH infections...
  29. ncbi Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole
    M Savlík
    Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, CZ 50005 Hradec Kralove, Czech Republic
    Res Vet Sci 83:20-6. 2007
    ..biotransformation enzymes and modulation of their activities by anthelmintics flubendazole (FLBZ) and mebendazole (MBZ) were investigated in subcellular fractions that were prepared from liver and small intestine of control ..
  30. ncbi Effect of single-dose albendazole and single-dose mebendazole on Necator americanus
    P Nontasut
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 20:237-42. 1989
    ..Group II, 54 children, received a single dose mebendazole, 600 mg. After treatment, repeated stool examination was performed on Day 14, Day 21 and Day 28...
  31. ncbi Integrated pharmacological assessment of flubendazole potential for use in sheep: disposition kinetics, liver metabolism and parasite diffusion ability
    L Moreno
    Laboratorio de Farmacologia, Departamento de Fisiopatologia, Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires UNCPBA, Campus Universitario, Tandil, Argentina
    J Vet Pharmacol Ther 27:299-308. 2004
    ..The data on FLBZ pharmacological behaviour presented here contribute to evaluate its potential to be developed as an anthelmintic for broad spectrum parasite control in ruminants...
  32. ncbi Population-based case-control study of mebendazole in pregnant women for birth outcomes
    Nandor Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Congenit Anom (Kyoto) 45:85-8. 2005
    The objectives of the study was to check the embryotoxic-teratogenic and fetotoxic effect of mebendazole (Vermox; Richter, Budapest, Hungary) treatment during pregnancy...
  33. ncbi [Effectiveness and safety of mebendazole compared to nitazoxanide in the treatment of Giardia lamblia in children]
    R Rodriguez-Garcia
    Servicio de Pediatria, Hospital General de Zona No 32, Instituto Mexicano del Seguro Social, Minatitlán, Veracruz
    Rev Gastroenterol Mex 64:122-6. 1999
    Compare the effectiveness and safety of mebendazole versus nitazoxanide in the treatment of Giardia lamblia in children...
  34. ncbi Evaluation of treatment and long-term follow-up in patients with hepatic alveolar echinococcosis
    Z Kadry
    Department of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland
    Br J Surg 92:1110-6. 2005
    ....
  35. ncbi Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool children
    Rebecca J Stoltzfus
    Division of Nutritional Sciences, Cornell University, Ithaca, NY UNICEF, Zanzibar, Tanzania
    J Nutr 134:348-56. 2004
    ..A 12-mo randomized, placebo controlled, double-blind trial of 10 mg daily iron and/or mebendazole (500 mg) every 3 mo was conducted in a community-based sample of 459 Zanzibari children age 6-71 mo with ..
  36. ncbi Reducing intestinal nematode infection: efficacy of albendazole and mebendazole
    A Bennett
    Wellcome Trust Centre for the Epidemiology of Infectious Disease WTCEID, University of Oxford, South Parks Road, Oxford, UK OX1 3FY
    Parasitol Today 16:71-4. 2000
    The widespread use of mebendazole and albendazole for treating intestinal nematode infections in human populations is raising concerns that careful monitoring pro- cedures should be in place to identify any emergence of drug resistance...
  37. pmc Combined treatment with interleukin-12 and mebendazole lessens the severity of experimental eosinophilic meningitis caused by Angiostrongylus cantonensis in ICR mice
    Wen Yuan Du
    Division of Parasitology, Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei Pesticide Toxicology Department, Taiwan Agricultural Chemicals and Toxic Substances Research Institute, Taichung, Taiwan
    Infect Immun 71:3947-53. 2003
    ..Mice were orally infected with 35 infective larvae. One group of mice were given a single dose of mebendazole (20 mg/kg of body weight) per os at various times and examined at 14 days postinfection (dpi) for worm recovery ..
  38. ncbi Efficacy of mebendazole and albendazole for Ascaris lumbricoides and hookworm infections in an area with long time exposure for antihelminthes, Northwest Ethiopia
    Solomon Adugna
    Department of Biochemistry, College of Medicine and Health Sciences, University of Gondar, P O Box 1391, Gondar, Ethiopia
    Ethiop Med J 45:301-6. 2007
    The efficacy of mebendazole and albendazole in the treatment of Ascaris lumbricoides and hookworm infections was evaluated in school children in an area with long time exposure for broad spectrum anthelminthic drugs.
  39. ncbi Low efficacy of mebendazole against hookworm in Vietnam: two randomized controlled trials
    Carsten Flohr
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    Am J Trop Med Hyg 76:732-6. 2007
    ..The treatment used in Vietnam is single dose oral mebendazole (Phardazone) 500 mg...
  40. pmc Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar
    M Albonico
    Ivo de Carneri Foundation, Milan, Italy
    Bull World Health Organ 81:343-52. 2003
    To evaluate the efficacy of and resistance to mebendazole (500 mg) and levamisole (40 or 80 mg), alone or in combination, for the treatment of Ascaris lumbricoides, Trichuris trichiura and hookworm infections on Pemba Island - an area ..
  41. ncbi Changed crystallinity of mebendazole solid dispersion: improved anthelmintic activity
    Juan J García-Rodriguez
    Department of Parasitology, Complutense University, 28040 Madrid, Spain
    Int J Pharm 403:23-8. 2011
    To improve the efficacy of mebendazole (MBZ), a poorly water-soluble drug, MBZ solid dispersions containing different proportions of low-substituted hydroxypropylcellulose (L-HPC) were prepared by lyophilization process...
  42. pmc Randomized clinical study of five days apostrophe therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children
    Roberto Canete
    Hygiene, Epidemiology and Microbiology Centre, Matanzas City, Cuba
    World J Gastroenterol 12:6366-70. 2006
    To compare the efficacy and safety of five days apostrophe therapy of mebendazole (MBZ) versus quinacrine (QC) on human giardiasis in children.
  43. ncbi A double-blind randomized controlled trial of antenatal mebendazole to reduce low birthweight in a hookworm-endemic area of Peru
    Renee Larocque
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada
    Trop Med Int Health 11:1485-95. 2006
    To assess the effect on birthweight of antenatal mebendazole plus iron vs. placebo plus iron in a highly hookworm-endemic area.
  44. ncbi Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells
    Nicole Doudican
    New York University School of Medicine, New York, NY 10016, USA
    Mol Cancer Res 6:1308-15. 2008
    ..Strikingly, 4 of the 10 compounds (mebendazole, albendazole, fenbendazole, and oxybendazole) are benzimidazoles, a class of structurally related, tubulin-..
  45. ncbi Albendazole and mebendazole have low efficacy against Trichuristrichiura in school-age children in Kabale District, Uganda
    Annette Olsen
    DBL Centre for Health Research and Development, Department of Disease Biology, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 57, DK 1871 Frederiksberg C, Denmark
    Trans R Soc Trop Med Hyg 103:443-6. 2009
    ..groups of Trichuris trichiura-infected school-age children were treated with one dose 400mg albendazole, 100mg mebendazole twice daily for 3 d, or 100mg mebendazole twice daily for 5 d...
  46. ncbi Failure of mebendazole in the treatment of humans with Trichinella spiralis infection at the stage of encapsulating larvae
    E Pozio
    Laboratory of Parasitology, Istituto Superiore di Sanita, Rome, Italy
    Clin Infect Dis 32:638-42. 2001
    ..mice were collected from muscle biopsies performed at different times (from 1 day to 16 months) following the end of treatment, indicating the failure of mebendazole to kill Trichinella parasites when they are encapsulating in muscles.
  47. ncbi A randomized trial comparing mebendazole and secnidazole for the treatment of giardiasis
    A A Escobedo
    Departamento de Parasitologia, Hospital Pediatrico Pedro Borrás, Calle F No 616 esquina a 27, Plaza, Ciudad de La Habana, CP 10400, Cuba
    Ann Trop Med Parasitol 97:499-504. 2003
    ..children (aged 5-15 years) with confirmed Giardia lamblia infection were randomly allotted to treatment with mebendazole (200 mg three times daily for 3 days) or secnidazole (30 mg/kg, in a single dose)...
  48. ncbi The efficacy of chemotherapy with mebendazole in human cystic echinococcosis: long-term follow-up of 52 patients
    C Bartoloni
    Istituto di Clinica Medica Generale e Terapia Medica, , , Rome, Italy
    Ann Trop Med Parasitol 86:249-56. 1992
    ..granulosus infection of the liver, lungs, bone and/or soft tissues were treated for several months with oral mebendazole (50-60 mg kg-1 day-1), in divided doses after fat-rich meals, either without surgery (WS), post-surgery (PS) or ..
  49. ncbi Soil-transmitted nematode infections and mebendazole treatment in Mafia Island schoolchildren
    M Albonico
    Ivo de Carneri Foundation, Via IV Marzo 14, 10122, Torino, Italy
    Ann Trop Med Parasitol 96:717-26. 2002
    ..americanus was more prevalent. This survey was followed by a parasitological evaluation of mebendazole treatment using a single, 500-mg dose...
  50. ncbi Effect of mebendazole on human cystic echinococcosis: the role of dosage and treatment duration
    K Vutova
    Department of Infectious Diseases, Parasitology, Epidemiology and Tropical Medicine, Faculty of Medicine, University of Medicine, Sofia, Bulgaria
    Ann Trop Med Parasitol 93:357-65. 1999
    Fifty-three patients with single, multiple and/or multi-organ hydatid cysts were treated with mebendazole, in varying dosages (30-70 mg/kg.day) and over varying periods (6-24 months)...
  51. ncbi Percutaneous aspiration-injection-reaspiration drainage plus albendazole or mebendazole for hepatic cystic echinococcosis: a meta-analysis
    Raymond A Smego
    Department of Medicine, Aga Khan University, Karachi, Pakistan
    Clin Infect Dis 37:1073-83. 2003
    ..cystic echinococcosis treated with percutaneous aspiration-injection-reaspiration (PAIR) plus albendazole or mebendazole (group 1) with 952 era-matched historical control subjects undergoing surgical intervention (group 2)...
  52. ncbi Comparative clinical trial of mebendazole and metronidazole in giardiasis of children
    S M Sadjjadi
    Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Iran
    J Trop Pediatr 47:176-8. 2001
    ..Each group received either mebendazole tablets 200 mg thrice daily for 5 days or metronidazole tablet 15 mg/kg/day in three divided doses, for 7 days...
  53. ncbi A comparative study of different albendazole and mebendazole regimens for the treatment of intestinal infections in school children of Usigu Division, western Kenya
    E M Muchiri
    Division of Vector Borne Diseases, Ministry of Health, Nairobi, Kenya
    J Parasitol 87:413-8. 2001
    ..the effectiveness of 4- and 6-mo repeated treatment with albendazole 600 mg (Zentel, SmithKline Beecham) or mebendazole 600 mg (Vermox, Janssen) on geohelminth infections was carried out on children in 6 primary schools; the study ..
  54. ncbi [Long term eradication rate of mebendazole therapy for strongyloidiasis]
    K Shikiya
    First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
    Kansenshogaku Zasshi 66:354-9. 1992
    We treated 245 strongyloidiasis patients with 7 schedules of mebendazole (MBZ) and obtained the eradication rates at 8 months to 2 years after the final treatment as described follows; MBZ (100 mg) was given twice a day orally...
  55. ncbi Pregnancy outcome after gestational exposure to mebendazole: a prospective controlled cohort study
    Orna Diav-Citrin
    Israeli Teratogen Information Service, Israel Ministry of Health, Jerusalem, Israel
    Am J Obstet Gynecol 188:282-5. 2003
    b>Mebendazole is an anthelmintic that is commonly needed in women of reproductive age. Its use in pregnancy is a reason for concern for women and their health care providers...
  56. ncbi Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo
    Tapas Mukhopadhyay
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 8:2963-9. 2002
    We have found that mebendazole (MZ), a derivative of benzimidazole, induces a dose- and time-dependent apoptotic response in human lung cancer cell lines...
  57. ncbi The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells
    Ji Ichiro Sasaki
    Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Cancer Ther 1:1201-9. 2002
    ..In this study, we assess mebendazole (MZ), a microtubule-disrupting anthelmintic that exhibits a potent antitumor property both in vitro and in vivo...
  58. ncbi Effect of mebendazole therapy during pregnancy on birth outcome
    N R de Silva
    Faculty of Medicine, University of Kelaniya, Sri Lanka
    Lancet 353:1145-9. 1999
    In areas endemic for hookworm, routine antenatal mebendazole therapy could greatly reduce the prevalence of anaemia in pregnancy...
  59. ncbi Surgery and postoperative mebendazole in the treatment of hydatid disease
    Fuad F Ammari
    Department of General Surgery, Faculty of Medicine, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan
    Saudi Med J 23:568-71. 2002
    ..Our aim is to establish the outcome of chemotherapy in the postoperative period on secondary hydatid cyst...
  60. ncbi Effects of the Zanzibar school-based deworming program on iron status of children
    R J Stoltzfus
    Center for Human Nutrition, Department of International Health, The Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
    Am J Clin Nutr 68:179-86. 1998
    ..n = 952), and 4 schools in which students received thrice-yearly deworming (n = 970) with 500 mg generic mebendazole. Schools were randomly selected for evaluation and allocated to program groups...
  61. pmc Outbreak of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with mebendazole and metronidazole use among Filipino laborers in Taiwan
    Kow Tong Chen
    Field Epidemiology Training Program, Center for Disease Control, Department of Health, Taipei, Taiwan, Republic of China
    Am J Public Health 93:489-92. 2003
    ..This study sought to identify the risk factors associated with an outbreak of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) among Filipino laborers in Taiwan...
  62. ncbi Mebendazole inhibits growth of human adrenocortical carcinoma cell lines implanted in nude mice
    Daniele Martarelli
    Department of Experimental Medicine and Public Health, University of Camerino, Via M Scalzino 3, 62032 Camerino Macerata, Italy
    Cancer Chemother Pharmacol 61:809-17. 2008
    ..Recently, mebendazole has been proved to be effective against different cancers...
  63. ncbi Flubendazole in cystic echinococcosis therapy: pharmaco-parasitological evaluation in mice
    Laura Ceballos
    Departamento de Fisiopatologia, Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires UNCPBA, Campus Universitario, 7000 Tandil, Argentina
    Parasitol Int 58:354-8. 2009
    ....
  64. ncbi Synthesis and antiparasitic activity of albendazole and mebendazole analogues
    Gabriel Navarrete-Vázquez
    Departamento de Farmacia, Facultad de Quimica, UNAM, CU, DF 04510, Mexico
    Bioorg Med Chem 11:4615-22. 2003
    Albendazole (Abz) and Mebendazole (Mbz) analogues have been synthesized and in vitro tested against the protozoa Giardia lamblia, Trichomonas vaginalis and the helminths Trichinella spiralis and Caenorhabditis elegans...
  65. ncbi A pediatric case of disseminated cystic echinococcosis successfully treated with mebendazole
    Zuhre Kaya
    Department of Pediatrics, Medical School of Gazi University, Ankara, Turkey
    Jpn J Infect Dis 57:7-9. 2004
    ..b>Mebendazole therapy produced complete resolution of the lung and kidney cysts...
  66. ncbi Increase in serum beta-carotene following dark green leafy vegetable supplementation in Mebendazole-treated school children in Bangladesh
    V Persson
    Section for International Maternal and Child Health, Uppsala University, Sweden
    Eur J Clin Nutr 55:1-9. 2001
    ..To study the effect of consumption of dark green leafy vegetables (DGLV) and sweet pumpkin on serum beta-carotene and retinol concentrations in children treated for Ascaris lumbricoides...
  67. ncbi Alveolar echinococcosis of the liver in an adult with human immunodeficiency virus type-1 infection
    W Zingg
    Division of Infectious Diseases and Hospital Epidemiology, Dept of Internal Medicine, University Hospital of Zurich, CH 8og91 Zurich, Switzerland
    Infection 32:299-302. 2004
    ..The patient had therapeutic mebendazole drug levels with only 1/10 of the normal drug dose...
  68. ncbi Brain metastasis of alveolar echinococcosis in a hyperendemic focus of Echinococcus multilocularis infection
    Y R Yang
    Molecular Parasitology Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Q 4006, Australia
    Trans R Soc Trop Med Hyg 99:937-41. 2005
    ..pregnancy, which may be suspected in this case, the favourable outcome after surgery and chemotherapy, and also a mental disability in a child following long-term intrauterine exposure to mebendazole, make the report particularly unique.
  69. ncbi Comparative efficacy of albendazole and three brands of mebendazole in the treatment of ascariasis and trichuriasis
    M Legesse
    Institute of Pathobiology, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    East Afr Med J 81:134-8. 2004
    ..the comparative efficacy of 400 mg albendazole (Smith Kline Beecham) as a single dose and three brands of mebendazole (Janssen, Unibios and East African Pharmaceuticals) at doses of 100 mg twice a day for three consecutive days ..
  70. ncbi A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children
    Roberto Canete
    Cuban Institute of Gastroenterology, Havana City, Cuba
    Curr Med Res Opin 22:2131-6. 2006
    ..However, cases refractory to treatment with these drugs are becoming more common worldwide...
  71. ncbi The effect of iron fortification and de-worming on anaemia and iron status of Vietnamese schoolchildren
    Thi Le Huong
    The Nutrition Department, Hanoi Medical University, No 1 Ton That Tung Str, Dongda, Hanoi, Viet Nam
    Br J Nutr 97:955-62. 2007
    ..anaemic children aged 6-8 years were randomly assigned to receive either iron-fortified noodles or placebo, and mebendazole or placebo...
  72. ncbi Spherical crystallization of mebendazole to improve processability
    Smiti Kumar
    Department of Pharmaceutical Technology Formulations, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India
    Pharm Dev Technol 13:559-68. 2008
    ..The present study was focused on spherical crystallization of an antihelmentic drug - Mebendazole (MBZ) - using spherical agglomeration technique...
  73. ncbi Treatment options for hepatic cystic echinococcosis
    Raymond A Smego
    Department of Medicine, The University of North Dakota, School of Medicine and Health Sciences, Fargo, ND, USA
    Int J Infect Dis 9:69-76. 2005
    ..Pre- and post-intervention chemotherapy with albendazole or mebendazole offers the advantage of reducing the risk of disease recurrence and intraperitoneal seeding of infection that ..
  74. ncbi Efficacy of benzimidazole carbamate on an intestinal fluke co-infected with nematodes
    Jitra Waikagul
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 88:233-7. 2005
    ..At day 7 after treatment, albendazole (400 mg) induced 42.5% cure rate, mebendazole (500 mg) a cure rate of 32.4%, on the other hand, praziquantel (40 mg/kg) gave 94...
  75. ncbi [Overview of therapeutic options for cystic echinococcosis]
    E Brunetti
    Divisione di Malattie Infettive e Tropicali, IRCCS Policlinico S Matteo, Universita di Pavia, Pavia
    Parassitologia 46:53-5. 2004
    ..Data from long-term follow-up studies are also discussed, with emphasis on the resulting stage-specific criteria for treatment...
  76. ncbi [Hydatid cyst of the kidney]
    H Ketata
    Service d Urologie, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Urol (Paris) 38:259-65. 2004
    ..The percutaneous management, which includes puncture, aspiration, injection, and reaspiration, can be performed in very selected cases. However, the results of this technique are still under debate...
  77. ncbi [Human alveolar echinococcosis: an emerging zoonosis in Hungary and Europe]
    Tamás Sréter
    Országos Allategészségügyi Intézet, Vadbetegségek és Parazitológiai Osztály, Budapest
    Orv Hetil 145:1655-63. 2004
    ..The aim of the present paper is to summarize the current knowledge on the life cycle and distribution of E. multilocularis, and the epidemiology, clinical features, diagnosis, treatment and control of human alveolar echinococcosis...
  78. ncbi [Nosology and epidemiology of human toxocarosis--the recent situation in Austria]
    Herbert Auer
    Abteilung fur Medizinische Parasitologie, Klinisches Institut fur Hygiene und Medizinische Mikrobiologie, Medizinische Universität Wien, Wien, Osterreich
    Wien Klin Wochenschr 116:7-18. 2004
    ....
  79. ncbi [The (children's) parasitic worms]
    Patrick L Scheid
    Laborabteilung I, Funktionsgebiet Diagnostik, Laborgruppe Med Mikrobiologie, Labor für Med Parasitologie, Zentrales Institut des Sanitätsdienstes der Bundeswehr Koblenz
    Kinderkrankenschwester 23:505-7. 2004
  80. ncbi Acute interstitial nephritis in a case of Ascaris lumbricoides infection
    Oliver Jung
    Department of Nephrology, Johann Wolfgang Goethe Univrsity, Frankfurt am Main, Germany
    Nephrol Dial Transplant 19:1625-8. 2004
  81. ncbi [Spontaneous resolution of a retrovesical hydatidic cyst]
    Emilio Pintor-Holguín
    Departamento de Especialidades Médicas, Facultad de Ciencias de la Salud, Universidad Europea de Madrid, Madrid
    Enferm Infecc Microbiol Clin 22:246-7. 2004
  82. ncbi Orthotopic liver transplantation for incurable alveolar echinococcosis: report of five cases from west China
    D Xia
    Center of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, People s Republic of China
    Transplant Proc 37:2181-4. 2005
    ..Specific management is needed to improve the results: earlier decision for OLT in symptomatic disease, routine pre- and post-transplant therapy, reduced immunosuppression, and regular follow-up...
  83. ncbi Albendazole for the treatment of human echinococcosis: a review of comparative clinical trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Am J Med Sci 334:171-9. 2007
    ..Albendazole has been used in various ways in the treatment of cystic echinococcosis (CE)...
  84. ncbi Single low-dose mebendazole administered quarterly for ascaris treatment
    John D Cleary
    School of Pharmacy, University of Mississippi Medical Center, Jackson, MS 39216, USA umsmed edu
    Am J Med Sci 333:340-5. 2007
    ..Intestinal parasites are difficult to eradicate in tropical climates where poor sanitation exists. In addition, pharmaceutical stability is poor making traditional three day dosing for the treatment of A. lumricoides challenging...
  85. ncbi An itchy holiday
    C van Nispen tot Pannerden
    Department of Internal Medicine, Infectious Diseases Section, Erasmus Medical Centre, Rotterdam, The Netherlands
    Neth J Med 65:188-90. 2007
    ..She was treated for various diagnoses, without success. Finally she was successfully treated for a clinically suspected hookwormrelated folliculitis. A brief overview of hookworm-related folliculitis is given...
  86. ncbi [Thoracic hydatid cysts: news]
    M Elbiaze
    Service des Maladies Respiratoires, hôpital Ibn Rochd, Casablanca Maroc
    Rev Mal Respir 23:10S80-10S82. 2006
  87. ncbi Mass treatment for intestinal helminthiasis control in an Amazonian endemic area in Brazil
    Marcio Neves Boia
    Laboratório de Doenças Parasitárias, Departamento de Medicina Tropical, IOC, FiocruzRJ, Brasil
    Rev Inst Med Trop Sao Paulo 48:189-95. 2006
    ..samples for parasitological examination in 308 individuals, followed by a mass treatment with albendazole or mebendazole with coverage of 83% of the city population in 2003...
  88. ncbi [Echinococcus granulosus--diagnostics and therapy problems--case report]
    Brygida Adamek
    Slaska Akademia Medyczna w Katowicach Katedra i Zakład Ogólnej Biologii Lekarskiej
    Pol Merkur Lekarski 20:560-2. 2006
    ..The necessity of taking the echinococcosis into account in occasionally found liver cysts differential diagnostics and individual choice of the optimal therapeutic schema was underlined...
  89. ncbi Should deworming be included in antenatal packages in hookworm-endemic areas of developing countries?
    Renee Larocque
    Department of Epidemiology and Biostatistics, McGill University, Montreal, QC
    Can J Public Health 97:222-4. 2006
    ..However, deworming has not been included in antenatal care packages in most developing countries...
  90. ncbi Chemotherapy of human cystic echinococcosis: comparative efficacy of mebendazole and albendazole
    T Todorov
    Medical Academy, Sofia, Bulgaria
    Ann Trop Med Parasitol 86:59-66. 1992
    The relative efficacy of mebendazole (MEB) and albendazole (ALB) was tested by treating 51 patients with single, multiple and multi-organ hydatid cysts; 28 patients were treated with MEB, 50-70 mg kg-1 body weight daily for six to 24 ..
  91. ncbi Hydatid disease of the liver and associated hepatocellular carcinoma
    Eva Zold
    University of Debrecen, 3rd Department of Medicine, Debrecen, Hungary
    Clin Gastroenterol Hepatol 3:xxxv. 2005
  92. ncbi The types and timing of the degenerative changes seen in the cysts during and after benzimidazole treatment of cystic echinococcosis
    T Todorov
    Department Clinic of Infectious, Parasitic and Tropical Diseases, Faculty of Medicine, University of Medicine, University Hospital St J Rilski, 1431 Sofia, Bulgaria
    Ann Trop Med Parasitol 99:649-59. 2005
    ..122 patients with abdominal and/or lung echinococcosis were randomly selected for treatment with albendazole or mebendazole. The main aims were to evaluate the effect of each drug on the hydatid cysts, to follow the changes in cyst ..
  93. ncbi An up-to-date on clinical management of human cystic echinococcosis
    A Teggi
    Dipartimento di Malattie Infettive, Ospedale Sant Andrea, University La Sapienza of Rome, Italy
    Parassitologia 46:405-7. 2004
    ..The therapeutic approach ranged from chemotherapy with benzimidazole carbamates (mebendazole and albendazole) to surgery, percutaneous non conventional treatment, and a "wait and see" approach, on the ..
  94. ncbi Clinical inquiries. What's the most effective treatment for giardiasis?
    Jeffrey D Kiser
    Eglin AFB Family Medicine Residency, Eglin AFB, FL, USA
    J Fam Pract 57:270-2. 2008
  95. ncbi Effect of two formulations of benzimidazole carbamates on the viability of cysts of Echinococcus granulosus in vivo
    K Daniel-Mwuambete
    Departamento de Parasitologia, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramon y Cajal s n, 28040 Madrid, Spain
    Parasite 10:371-3. 2003
    Two different preparations, solution and suspension, of three benzimidazole carbamate drugs, mebendazole, albendazole and ricobendazole, were compared by analyzing their in vivo activity against Echinococcus granulosus cysts in a mouse ..
  96. ncbi [Adult ascaris in the intrahepatic bile ducts]
    M C Receveur
    Service de Medecine, centre hospitalier de Mayotte, BP 04, 97600 Mamoudzou
    Presse Med 31:1705. 2002
  97. ncbi Evaluation of the Integrated Management of Childhood Illness guidelines for treatment of intestinal helminth infections among sick children aged 2-4 years in western Kenya
    Renu Garg
    International Child Survival and Emerging Infections Program Support Activity, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Mail Stop F 22, 4770 Buford Hwy, Atlanta, Georgia 30341, USA
    Trans R Soc Trop Med Hyg 96:543-8. 2002
    ..and to evaluate the nutritional benefit of treating sick children without pallor with an anthelmintic (mebendazole is already part of IMCI treatment for sick children aged 2-4 years with palmar pallor in areas where hookworm ..
  98. ncbi Two cases of imported gnathostomiasis in Spanish women
    S Puente
    Seccion de Medicina Tropical, Servicio de Enfermedades Infecciosas, Hospital Carlos III, 28029 Madrid, Spain
    Eur J Clin Microbiol Infect Dis 21:617-20. 2002
    ..The cases reported here demonstrate the increasing frequency with which human gnathostomiasis is being diagnosed in nonendemic countries as a result of more extensive international travel and migration...
  99. ncbi [Hepatic round focus with pruritus]
    Peter Stiefelhagen
    DRK Krankenhaus Westerwald, D 57627 Hachenburg
    MMW Fortschr Med 145:47, 51. 2003
  100. ncbi Percutaneous sonographically guided treatment of hydatid cysts in sheep: direct injection of mebendazole and albendazole
    Yahya Paksoy
    Ultra Görüntüleme Merkezi, Konya, Turkey
    J Ultrasound Med 22:797-803. 2003
    ..The purpose of this study was to investigate the scolicidal effect of intracystic injection of benzimidazolic solutions in naturally infected sheep with hydatid disease...
  101. ncbi Primary ovarian echinococcosis
    Sema Zergeroglu
    Department of Pathology, Zekai Tahir Burak Hospital, Ankara, Turkey
    Arch Gynecol Obstet 270:285-6. 2004
    ..The incidence of genital system hydatid disease in abdominal operation is 0.1%. During a period of 20 years (1957-1977), 12 cases were reported. This disease has no specific symptoms and findings. It is diagnosed intraoperatively...

Research Grants7

  1. Phase II clinical trial of stage specific treatment of cystic echinococcosis (Ech
    Thomas Junghanss; Fiscal Year: 2010
    ..aspiration, injection of protoscolicidal agent, reaspiration), (3) chemotherapy with albendazole (ABZ) or mebendazole (MBZ), and (4) watch and wait for inactive, clinically silent cysts...
  2. A Strategy to Reduce Stunting of Growth in Early Infancy: a Global Network Study
    Carl Bose; Fiscal Year: 2013
    ..In this study, we will use the ati-parasitic drug, mebendazole. Because there is little knowledge about the pharmacokinetics (PK) and safety of this drug (or any other anti-..
  3. TRICHINELLOSIS AND REGULATION OF HOST GENE EXPRESSION
    Douglas Jasmer; Fiscal Year: 2001
    ..Methods were developed to extract these nuclear antigens (NA). It was further shown that mebendazole treatment of mice depletes NA from host nuclei and simultaneously leads to diminution in size of infected cell ..
  4. APLASTIC ANEMIA EPIDEMIOLOGY--INCIDENCE AND CASE CONTROL
    David Kaufman; Fiscal Year: 2000
    ..g., mebendazole). The new phase of data collection has already begun with support from other sources, which will cover 2...
  5. HOOKWORM LARVAL INFECTIVITY AND DEVELOPMENT
    Peter Hotez; Fiscal Year: 2002
    ..The pharmacologic manipulation of parasite-derived protein kinases may offer a new approach to chemotherapy by taking larvae out of arrest. ..
  6. Heavy Metal Exposures in Women and Children, the Role of Nutrients
    Rebecca Stoltzfus; Fiscal Year: 2007
    ..The symposium will result in proceedings published in the Journal of Nutrition, one of the most widely read nutrition publications. [unreadable] [unreadable] [unreadable] [unreadable]..
  7. Antenatal and preschool iron and zinc use and cognition
    Parul Christian; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..