pyrantel tartrate

Summary

Summary: Broad spectrum anthelmintic for livestock.

Top Publications

  1. ncbi Liquid chromatographic determination of pyrantel tartrate in medicated formulations
    Joyce A Konrardy
    Pfizer Global Manufacturing, Quality Operations, One Pfizer Way, Lee s Summit, MO 64081, USA
    J AOAC Int 86:882-7. 2003
  2. ncbi Pyrantel pamoate resistance in horses receiving daily administration of pyrantel tartrate
    Emily L Brazik
    Carolina Coastal Equine Veterinary Service, 1286 Hwy 117 N, Burgaw, NC 28425, USA
    J Am Vet Med Assoc 228:101-3. 2006
  3. ncbi Experimental cyathostome challenge of ponies maintained with or without benefit of daily pyrantel tartrate feed additive: comparison of parasite burdens, immunity and colonic pathology
    C M Monahan
    Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Lousiana State University, Baton Rouge 70803, USA
    Vet Parasitol 74:229-41. 1998
  4. ncbi The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs
    P Hördegen
    Department of Veterinary Parasitology, Research Institute of Organic Agriculture, Ackerstrasse, CH 5070 Frick, Switzerland
    Vet Parasitol 117:51-60. 2003
  5. ncbi In vitro screening of six anthelmintic plant products against larval Haemonchus contortus with a modified methyl-thiazolyl-tetrazolium reduction assay
    P Hördegen
    Department of Veterinary Parasitology, Research Institute of Organic Agriculture, Ackerstrasse, 5070 Frick, Switzerland
    J Ethnopharmacol 108:85-9. 2006
  6. ncbi Activity of selected antioxidative enzymes in rats exposed to dimethoate and pyrantel tartrate
    D Barski
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10 719 Olsztyn, Poland
    Pol J Vet Sci 15:239-45. 2012
  7. ncbi Cases of reduced cyathostomin egg-reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms
    G von Samson-Himmelstjerna
    Institute for Parasitology, University of Veterinary Medicine, Buenteweg 17, 30559 Hannover, Germany
    Vet Parasitol 144:74-80. 2007
  8. ncbi Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically
    E T Lyons
    Department of Veterinary Science, University of Kentucky, Gluck Equine Research Center, Lexington, KY 40546 0099, USA
    Parasitol Res 100:473-8. 2007
  9. ncbi Progress on the development and single-laboratory validation of a high-performance liquid chromatographic method for the determination of carbadox and pyrantel tartrate in type B and C medicated feeds
    Jane Z Sabbatini
    Covance Laboratories, 3301 Kinsman Blvd, Madison, WI 53704, USA
    J AOAC Int 92:26-33. 2009
  10. ncbi Cyathostomes in horses in Canada resistant to pyrantel salts and effectively removed by moxidectin
    J Owen D Slocombe
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ont, Canada
    Vet Parasitol 140:181-4. 2006

Scientific Experts

  • Eugene Lyons
  • Georg von Samson-Himmelstjerna
  • D S Lindsay
  • J Owen D Slocombe
  • Jane Z Sabbatini
  • P Hördegen
  • D Barski
  • M A M Harfoush
  • Emily L Brazik
  • C M Monahan
  • Mary G Rossano
  • W Langhans
  • H Hertzberg
  • V Maurer
  • Joyce A Konrardy
  • A Spodniewska
  • E A Kruttlin
  • M A el-Seify
  • El Aal A M I Abd
  • Jan T Luquire
  • Dianne Little
  • J Cabaret
  • D D French
  • H W Taylor
  • Melissa T Hines
  • Linda S Mansfield
  • Debra C Sellon
  • Jon S Patterson
  • John B Kaneene
  • J P Dubey
  • Hany M Elsheikha
  • Elizabeth A Kruttlin
  • T R Klei
  • Harold C Schott
  • M R Chapman
  • Alice J Murphy
  • Gregory K Webster
  • J Heilmann
  • Mary A Burner
  • Mark A Litchman
  • Tommy W Garner
  • H C Schott
  • M G Rossano
  • R A Vrable
  • J B Kaneene
  • A J Murphy
  • L S Mansfield
  • R A Valdez
  • C Chartier
  • M Stankiewicz
  • R P Herd
  • C Benoit
  • L L Hungerford
  • I Pors
  • J A Dipietro
  • A J Paul
  • K S Todd
  • T F Lock
  • J Hubert
  • G A Majewski
  • D L Froe
  • V A Thorpe
  • D Kerboeuf
  • L L Southern
  • M O Abatan
  • G A Conder
  • E L Jeska
  • W Jonas
  • E Bodak-Koszalka
  • P G Hoyt
  • M E Bessette
  • T B Stewart
  • D L Leon
  • P M Guimond
  • S S Johnson
  • D L Cox
  • B L Lee

Detail Information

Publications26

  1. ncbi Liquid chromatographic determination of pyrantel tartrate in medicated formulations
    Joyce A Konrardy
    Pfizer Global Manufacturing, Quality Operations, One Pfizer Way, Lee s Summit, MO 64081, USA
    J AOAC Int 86:882-7. 2003
    The validation of a novel liquid chromatographic (LC) method for the determination of pyrantel tartrate in feed is presented. The method provides a significant improvement over the efficiency and precision of AOAC Official Method 978.30...
  2. ncbi Pyrantel pamoate resistance in horses receiving daily administration of pyrantel tartrate
    Emily L Brazik
    Carolina Coastal Equine Veterinary Service, 1286 Hwy 117 N, Burgaw, NC 28425, USA
    J Am Vet Med Assoc 228:101-3. 2006
    16 horses treated daily with pyrantel tartrate (2.64 mg/kg [1.2 mg/lb], PO) as part of a prophylactic anthelmintic program.
  3. ncbi Experimental cyathostome challenge of ponies maintained with or without benefit of daily pyrantel tartrate feed additive: comparison of parasite burdens, immunity and colonic pathology
    C M Monahan
    Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Lousiana State University, Baton Rouge 70803, USA
    Vet Parasitol 74:229-41. 1998
    ..Following OBZ treatment, Group 1 ponies were treated with pyrantel tartrate (PT) in their pelleted ration; the remaining ponies received only the pelleted ration...
  4. ncbi The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs
    P Hördegen
    Department of Veterinary Parasitology, Research Institute of Organic Agriculture, Ackerstrasse, CH 5070 Frick, Switzerland
    Vet Parasitol 117:51-60. 2003
    ..Caesalpiniaceae); group F with 25 mg/kg BW of pyrantel tartrate and group G with 50% ethanol. Group H remained untreated. Only the ethanol extract of F...
  5. ncbi In vitro screening of six anthelmintic plant products against larval Haemonchus contortus with a modified methyl-thiazolyl-tetrazolium reduction assay
    P Hördegen
    Department of Veterinary Parasitology, Research Institute of Organic Agriculture, Ackerstrasse, 5070 Frick, Switzerland
    J Ethnopharmacol 108:85-9. 2006
    ..b>Pyrantel tartrate was used as reference anthelmintic...
  6. ncbi Activity of selected antioxidative enzymes in rats exposed to dimethoate and pyrantel tartrate
    D Barski
    Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10 719 Olsztyn, Poland
    Pol J Vet Sci 15:239-45. 2012
    This study presents the results of research concerning the effect of single and combined application of pyrantel tartrate and dimethoate on selected antioxidative enzymes: catalase (CAT), superoxide dismutase (SOD) and glutathione ..
  7. ncbi Cases of reduced cyathostomin egg-reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms
    G von Samson-Himmelstjerna
    Institute for Parasitology, University of Veterinary Medicine, Buenteweg 17, 30559 Hannover, Germany
    Vet Parasitol 144:74-80. 2007
    ..On one farm in 2 consecutive years, IVM treatment did not lead to a significant reduction in P. equorum faecal egg counts in one and five young horses, respectively...
  8. ncbi Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically
    E T Lyons
    Department of Veterinary Science, University of Kentucky, Gluck Equine Research Center, Lexington, KY 40546 0099, USA
    Parasitol Res 100:473-8. 2007
    Foals (79), born in 2004 on three thoroughbred horse farms (C, M, and S) in central Kentucky, were fed pyrantel tartrate daily, beginning at about 3 months of age...
  9. ncbi Progress on the development and single-laboratory validation of a high-performance liquid chromatographic method for the determination of carbadox and pyrantel tartrate in type B and C medicated feeds
    Jane Z Sabbatini
    Covance Laboratories, 3301 Kinsman Blvd, Madison, WI 53704, USA
    J AOAC Int 92:26-33. 2009
    Carbadox, an antimicrobial agent, and pyrantel tartrate, an anthelmintic, are feed additives that are often used in combination in the United States...
  10. ncbi Cyathostomes in horses in Canada resistant to pyrantel salts and effectively removed by moxidectin
    J Owen D Slocombe
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ont, Canada
    Vet Parasitol 140:181-4. 2006
    ..Eleven of 15 yearlings, which had been on a daily feeding of grain with pyrantel tartrate for 66 d were found with strongyle eggs in feces...
  11. ncbi The effects of pyrantel tartrate on Sarcocystis neurona merozoite viability
    E A Kruttlin
    Department of Large Animal Clinical Sciences, D201 Veterinary Medicine Center, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Vet Ther 2:268-76. 2001
    ..The present study was designed to test the hypothesis that pyrantel tartrate can kill S. neurona merozoites growing in equine dermal cell culture...
  12. ncbi Effect of daily administration of pyrantel tartrate in preventing infection in horses experimentally challenged with Sarcocystis neurona
    Mary G Rossano
    Population Medicine Center, Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
    Am J Vet Res 66:846-52. 2005
    To determine whether daily administration of pyrantel tartrate can prevent infection in horses experimentally challenged with Sarcocystis neurona.
  13. ncbi Resistance of gastrointestinal nematodes of sheep to some anthelmintics
    M A M Harfoush
    Animal Health Research Institute, Dokki, Kafr El Sheikh Branch, Department of Parasitology, Faculty of Veterinary Medicine, Kafr El Sheikh University, Kafr EL Sheikh, Egypt
    J Egypt Soc Parasitol 40:377-82. 2010
    The occurrence of resistance to three of commonly used anthelmintics, Pyrantel tartrate (Banminth), Albendazole2...
  14. ncbi Determination of the activity of pyrantel tartrate against Sarcocystis neurona in gamma-interferon gene knockout mice
    D S Lindsay
    Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, 1410 Prices Fork Road, Blacksburg, VA 24061 0342, USA
    Vet Parasitol 97:141-4. 2001
    ..Some horse owners and equine clinicians believe that horses which are on daily pyrantel tartrate at 2.64mg/kg for helminth prophylaxis are less likely to develop EPM...
  15. ncbi Foals raised on pasture with or without daily pyrantel tartrate feed additive: comparison of parasite burdens and host responses following experimental challenge with large and small strongyle larvae
    C M Monahan
    Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA
    Vet Parasitol 73:277-89. 1997
    ..Mares and foals of Group 1 received daily pyrantel tartrate (PT) treatment with their pelleted feed ration, whereas mares and foals of Groups 2 and 3 received only the ..
  16. ncbi A microlarval development assay for the detection of anthelmintic resistance in sheep nematodes
    J Hubert
    Station de Pathologie Aviaire et de Parasitologie, Unité d Helminthologie, Monnaie, France
    Vet Rec 130:442-6. 1992
    ..Good dose-response data were obtained with thiabendazole, levamisole, pyrantel tartrate and ivermectin allowing the determination of the 50 per cent lethal concentration and of resistance factors ..
  17. ncbi Concurrent infections with the ruminant nematodes Haemonchus contortus and Trichostrongylus colubriformis in jirds, Meriones unguiculatus, and use of this model for anthelmintic studies
    G A Conder
    Parasitology Research, Upjohn Labortories, Kalamazoo, Michigan 49001
    J Parasitol 77:621-3. 1991
    ..This model, using worms of 2 genera living in distinct sites, allows preliminary evaluation of anthelmintic activity and spectrum for experimental compounds in a single cost- and resource-efficient experiment...
  18. ncbi Efficacy of some commercial formulations of anthelmintics on Haemonchus contortus and Trichostrongylus columbianum
    M O Abatan
    University of Ibadan, Faculty of Veterinary Medicine, Department of Veterinary Physiology and Pharmacology, Nigeria
    J Chemother 2:377-9. 1990
    ..Levamisole and Banminth affected the motility of the helminth larvae with subsequent death after 24h. The other anthelmintics used did not adversely affect the helminth larvae as compared with the untreated control group...
  19. ncbi Evaluation of pyrantel-tartrate abbreviated Ascaris suum infections for the development of resistance in young pigs against migrating larvae
    M Stankiewicz
    Veterinary Medical Research Institute, Iowa State University, Ames 50011
    Int J Parasitol 20:77-81. 1990
    ..suum until they were divided into groups at the age of 7-8 weeks. The experimental animals received pyrantel tartrate during the period when they were being exposed to increasing numbers of infective A...
  20. ncbi Acquired resistance to migrating larvae of Ascaris suum in young pigs by repeated drug-abbreviated infections
    M Stankiewicz
    Veterinary Medical Research Institute, Iowa State University, Ames 50011
    J Parasitol 76:383-8. 1990
    ..suum eggs (500, 1,000, 2,000, 5,000, 10,000, and 20,000) at 7-day intervals while the pigs were receiving pyrantel tartrate in the feed...
  21. ncbi Effect of fenbendazole and pyrantel tartrate on the induction of protective immunity in pigs naturally or experimentally infected with Ascaris suum
    L L Southern
    Louisiana State University Agricultural Center, Baton Rouge
    J Anim Sci 67:628-34. 1989
    ..Pigs in Treatments 2 and 5 were medicated with pyrantel tartrate (PT, 106 mg/kg feed) for 28 d. Pigs in Treatments 3 and 6 served as infected, unmedicated controls...
  22. ncbi A collaborative study: high-pressure liquid chromatographic determination of carbadox and pyrantel tartrate in animal feeds
    V A Thorpe
    Michigan Department of Agriculture, Laboratory Division, East Lansing 48823
    J Chromatogr Sci 26:545-50. 1988
    Carbadox (CBX), an antibacterial agent, and pyrantel tartrate (PT), an anthelmintic, are formulated either separately or together in swine feeds...
  23. ncbi Efficacy of pyrantel tartrate against experimental infections with Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus colubriformis in goats
    C Chartier
    CNEVA, Station Régionale de Pathologie Caprine, Niort, France
    Vet Parasitol 59:69-73. 1995
    The efficacy of pyrantel tartrate was evaluated in goats against induced infections with Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus colubriformis...
  24. ncbi Comparison of daily and monthly pyrantel treatment in yearling thoroughbreds and the protective effect of strategic medication of mares on their foals
    R P Herd
    Department of Veterinary Preventive Medicine, Ohio State University, Columbus 43210
    Vet Parasitol 55:93-104. 1994
    ..on a Thoroughbred breeding farm in Ohio were done to: (1) compare the effects of daily administration of pyrantel tartrate feed pellets with monthly administration of a pyrantel pamoate paste to yearling horses (21 January-3 ..
  25. ncbi Controlled efficacy study of the bioequivalence of Strongid C and generic pyrantel tartrate in horses
    R A Valdez
    Department of Veterinary Pathobiology, University of Illinois, Urbana 61801, USA
    Vet Parasitol 60:83-102. 1995
    The bioequivalence of Strongid C and generic pyrantel tartrate was determined in a controlled study using 30 horses with naturally acquired endoparasitic infections...
  26. ncbi Patent infections of Ascaris suum in pigs: effect of previous exposure to multiple, high doses of eggs and various treatment regimes
    M Stankiewicz
    Wallaceville Animal Research Centre, Ministry of Agriculture and Fisheries, Upper Hutt, New Zealand
    Int J Parasitol 22:597-601. 1992
    ..When prechallenge infections were removed by pyrantel tartrate treatment the animals were more susceptible to challenge than controls not previously exposed to infections...