miconazole

Summary

Summary: An imidazole antifungal agent that is used topically and by intravenous infusion.

Top Publications

  1. ncbi [Drug-drug interaction of antifungal drugs]
    Toshiro Niwa
    Post Marketing Product Development, Astellas Pharma Inc, Osaka, Japan
    Yakugaku Zasshi 125:795-805. 2005
  2. ncbi Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole
    Anna Bink
    Centre of Microbial and Plant Genetics, CMPG, Katholieke Universiteit Leuven, 3001 Heverlee, Belgium
    Antimicrob Agents Chemother 55:4033-7. 2011
  3. ncbi Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest
    Chih-Hsiung Wu
    School of Medicine, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 180:22-35. 2002
  4. ncbi Miconazole induces fungistasis and increases killing of Candida albicans subjected to photodynamic therapy
    Sara B Snell
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Photochem Photobiol 88:596-603. 2012
  5. ncbi Fungicidal activity of miconazole against Candida spp. biofilms
    Davy Vandenbosch
    Laboratory of Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B 9000 Ghent, Belgium
    J Antimicrob Chemother 65:694-700. 2010
  6. ncbi Comparison of the efficacy and safety of miconazole 50-mg mucoadhesive buccal tablets with miconazole 500-mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in patients
    Rene Jean Bensadoun
    Department of Radiation Oncology, Antoine Lacassagne Center, Nice, France
    Cancer 112:204-11. 2008
  7. ncbi In vitro synergism between berberine and miconazole against planktonic and biofilm Candida cultures
    Guo Xian Wei
    Department of Pediatric Dentistry, University of Illinois at Chicago, College of Dentistry, MC850, Chicago, IL 60612 7212, USA
    Arch Oral Biol 56:565-72. 2011
  8. ncbi Susceptibility of Candida albicans biofilms grown in a constant depth film fermentor to chlorhexidine, fluconazole and miconazole: a longitudinal study
    Hanadi Lamfon
    Division of Infection and Immunity, Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X 8LD, UK
    J Antimicrob Chemother 53:383-5. 2004
  9. ncbi Inhibitory effect of miconazole on melanogenesis
    Yeun Ja Mun
    Department of Herbal Resources, Wonkwang University, Iksan, Jeonbuk, Korea
    Biol Pharm Bull 27:806-9. 2004
  10. ncbi Antifungal activity of miconazole against recent Candida strains
    N Isham
    Center for Medical Mycology, Case Western Reserve University, Cleveland, OH 44106, USA
    Mycoses 53:434-7. 2010

Research Grants

  1. ANTIFUNGAL RESPONSE--MDR INDUCTION
    Thomas Edlind; Fiscal Year: 2002
  2. Estrogen and brain vascular inflammation in diabetics
    Dale Pelligrino; Fiscal Year: 2007
  3. TEXAS SOUTHERN UNIVERSITY RESEARCH SCIENTIST AWARD
    Adebayo Oyekan; Fiscal Year: 2007
  4. 20-HETE IN NO-MEDIATED REGULATION OF RENAL FUNCTION
    Adebayo Oyekan; Fiscal Year: 2001
  5. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt Barnhart; Fiscal Year: 2007
  6. CANDIDACIDAL MECHANISMS OF SALIVARY HISTATINS
    Mira Edgerton; Fiscal Year: 2007
  7. HISTAMINERGIC MECHANISMS OF ANTINOCICEPTION
    LINDSAY HOUGH; Fiscal Year: 2007
  8. Estrogen and EDHF in NO Deficiency
    An Huang; Fiscal Year: 2006
  9. P450 Epoxygenase Mechanisms of Opioid Analgesia
    LINDSAY HOUGH; Fiscal Year: 2010
  10. Estrogen and EDHF in NO Deficiency
    An Huang; Fiscal Year: 2010

Detail Information

Publications193 found, 100 shown here

  1. ncbi [Drug-drug interaction of antifungal drugs]
    Toshiro Niwa
    Post Marketing Product Development, Astellas Pharma Inc, Osaka, Japan
    Yakugaku Zasshi 125:795-805. 2005
    ..pharmacokinetic drug-drug interactions with antifungal drugs, including fluconazole, itraconazole, micafungin, miconazole, and voriconazole...
  2. ncbi Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole
    Anna Bink
    Centre of Microbial and Plant Genetics, CMPG, Katholieke Universiteit Leuven, 3001 Heverlee, Belgium
    Antimicrob Agents Chemother 55:4033-7. 2011
    We investigated the cellular mechanisms responsible for the occurrence of miconazole-tolerant persisters in Candida albicans biofilms. Miconazole induced about 30% killing of sessile C. albicans cells at 75 μM...
  3. ncbi Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest
    Chih-Hsiung Wu
    School of Medicine, Taipei Medical University, Taipei, Taiwan
    Toxicol Appl Pharmacol 180:22-35. 2002
    b>Miconazole (MIC), a promising oral antifungal agent, has been used worldwide in the treatment of superficial mycosis...
  4. ncbi Miconazole induces fungistasis and increases killing of Candida albicans subjected to photodynamic therapy
    Sara B Snell
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Photochem Photobiol 88:596-603. 2012
    ..Based on the ability of the antifungal miconazole to induce ROS in Candida, we tested several azole antifungals for their ability to augment PDT in vitro...
  5. ncbi Fungicidal activity of miconazole against Candida spp. biofilms
    Davy Vandenbosch
    Laboratory of Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B 9000 Ghent, Belgium
    J Antimicrob Chemother 65:694-700. 2010
    Although azole antifungals are considered to be fungistatic, miconazole has fungicidal activity against planktonic Candida albicans cells, presumably associated with the induction of reactive oxygen species (ROS) production...
  6. ncbi Comparison of the efficacy and safety of miconazole 50-mg mucoadhesive buccal tablets with miconazole 500-mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in patients
    Rene Jean Bensadoun
    Department of Radiation Oncology, Antoine Lacassagne Center, Nice, France
    Cancer 112:204-11. 2008
    ..b>Miconazole Lauriad 50-mg mucoadhesive buccal tablet (MBT) Loramyc reportedly delivered rapid and prolonged, effective ..
  7. ncbi In vitro synergism between berberine and miconazole against planktonic and biofilm Candida cultures
    Guo Xian Wei
    Department of Pediatric Dentistry, University of Illinois at Chicago, College of Dentistry, MC850, Chicago, IL 60612 7212, USA
    Arch Oral Biol 56:565-72. 2011
    ..To investigate the antimycotic activity of the plant alkaloid berberine (BBR), alone and in combination with antifungal azoles, against planktonic and biofilm Candida cultures...
  8. ncbi Susceptibility of Candida albicans biofilms grown in a constant depth film fermentor to chlorhexidine, fluconazole and miconazole: a longitudinal study
    Hanadi Lamfon
    Division of Infection and Immunity, Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X 8LD, UK
    J Antimicrob Chemother 53:383-5. 2004
    ..The MIC of fluconazole, miconazole and chlorhexidine for C. albicans was first determined...
  9. ncbi Inhibitory effect of miconazole on melanogenesis
    Yeun Ja Mun
    Department of Herbal Resources, Wonkwang University, Iksan, Jeonbuk, Korea
    Biol Pharm Bull 27:806-9. 2004
    b>Miconazole (MIC), a regional antifungal agent, has been used worldwide in the treatment of superficial mycosis. However, the effect of MIC on skin pigmentation is not known...
  10. ncbi Antifungal activity of miconazole against recent Candida strains
    N Isham
    Center for Medical Mycology, Case Western Reserve University, Cleveland, OH 44106, USA
    Mycoses 53:434-7. 2010
    b>Miconazole (MICON) has long been used for the topical treatment of mucosal candidiasis...
  11. ncbi Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast
    Karin Thevissen
    Centre of Microbial and Plant Genetics, Katholieke Universiteit Leuven, Heverlee, Belgium
    J Biol Chem 282:21592-7. 2007
    The antifungal compound miconazole inhibits ergosterol biosynthesis and induces reactive oxygen species (ROS) in susceptible yeast species...
  12. ncbi Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis
    Jens Van Roey
    Tibotec BVBA, Mechelen, Belgium
    J Acquir Immune Defic Syndr 35:144-50. 2004
    This randomized comparative study assessed the efficacy and safety of a 10-mg once-daily topical regimen of miconazole nitrate mucoadhesive buccal tablet (n = 178) versus a 400-mg once-daily systemic regimen of ketoconazole (n = 179) in ..
  13. ncbi Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole
    Riina Rautemaa
    Department of Microbiology and Immunology, Haartman Institute, University of Helsinki, Finland
    Scand J Infect Dis 40:904-7. 2008
    ..Significantly more y of usage of ketoconazole and miconazole preceded the isolation of strains with decreased susceptibility to fluconazole than susceptible isolates (p=0...
  14. ncbi Susceptibility to 5-fluorocytosine, miconazole and amphotericin B of Candida albicans strains isolated from the throat of non-AIDS patients
    Gloria Luz Paniagua
    Facultad de Estudios Superiores Iztacala, UNAM
    Rev Latinoam Microbiol 44:65-8. 2002
    ..Minimal inhibitory concentrations (MIC) of 5-fluorocytosine, miconazole and amphotericin B were determined by microtiter broth dilution...
  15. ncbi Randomized, comparative, double-blind, double-dummy, multicenter trial of miconazole buccal tablet and clotrimazole troches for the treatment of oropharyngeal candidiasis: study of miconazole Lauriad® efficacy and safety (SMiLES)
    Jose A Vazquez
    Division of Infectious Diseases, Henry Ford Hospital, Detroit, Michigan 48201, USA
    HIV Clin Trials 11:186-96. 2010
    ..Once-daily miconazole 50 mg buccal tablet (MBT) is a novel delivery system using an extended-spectrum azole with potent in vitro ..
  16. ncbi Cyclodextrin-functionalized biomaterials loaded with miconazole prevent Candida albicans biofilm formation in vitro
    Cesar A B Nava-Ortiz
    Departamento de Quimica de Radiaciones y Radioquimica, Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico DF 04510, Mexico
    Acta Biomater 6:1398-404. 2010
    ..functionalization with CDs provided PE and PP with the capability to incorporate the anti-fungal drug miconazole (up to 0.27 mg cm(-2)), leading to reduced biofilm formation by C. albicans in an in vitro biofilm model system...
  17. ncbi Miconazole gel compared with Zataria multiflora Boiss. gel in the treatment of denture stomatitis
    Massoud Amanlou
    Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, 14155 6451, Iran
    Phytother Res 20:966-9. 2006
    An open, randomized, controlled study with two parallel treatment groups was done to evaluate the efficacy of a miconazole 2% gel compared with Zataria multiflora 0...
  18. ncbi Endogenous reactive oxygen species is an important mediator of miconazole antifungal effect
    Daisuke Kobayashi
    Department of Clinical Laboratory Medicine. Division of Laboratory Diagnosis, Sapporo Medical University School of Medicine, Japan
    Antimicrob Agents Chemother 46:3113-7. 2002
    We investigated the significance of endogenous reactive oxygen species (ROS) produced by fungi treated with miconazole. ROS production in Candida albicans was measured by a real-time fluorogenic assay...
  19. ncbi Comparison of the pharmacokinetics of miconazole after administration via a bioadhesive slow release tablet and an oral gel to healthy male and female subjects
    J M Cardot
    Laboratoire de Biopharmacie, Faculte de Pharmacie, 28 Place Henri Dunant, BP 38, F 63001 Clermont Ferrand, France
    Br J Clin Pharmacol 58:345-51. 2004
    The aim of this study was to compare salivary miconazole pharmacokinetics following once daily application of bioadhesive tablets (50 or 100 mg), vs the current treatment with a gel (3 times a day, 375 mg day(-1)).
  20. ncbi Tensidols, new potentiators of antifungal miconazole activity, produced by Aspergillus niger FKI-2342
    Takashi Fukuda
    Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
    J Antibiot (Tokyo) 59:480-5. 2006
    ..Tensidols A and B potentiated miconazole activity against Candida albicans...
  21. ncbi Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial
    Nedim Yucel
    2nd Department of Surgery, Klinikum Merheim, Germany
    J Antimicrob Chemother 54:1109-15. 2004
    Central venous catheters (CVC) are a major cause of nosocomial bloodstream infections. Catheters modified with miconazole and rifampicin that constantly and slowly release antimicrobial substances are assumed to be beneficial in reducing ..
  22. ncbi Preparation and in vitro/in vivo evaluation of the buccal bioadhesive properties of slow-release tablets containing miconazole nitrate
    Fergany A Mohammed
    Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt
    Drug Dev Ind Pharm 29:321-37. 2003
    Slow-release buccal bioadhesive tablets of miconazole nitrate were prepared by using polymer mixtures of buccoadhesive materials such as hydroxypropylmethylcellulose, sodium carboxymethylcellulose, carbopol 934p, and sodium alginate...
  23. ncbi Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%
    Erin M Warshaw
    Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    J Am Acad Dermatol 53:717-20. 2005
    ..double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence...
  24. ncbi Physical and chemical stability of miconazole liposomes prepared by supercritical aerosol solvent extraction system (ASES) process
    Sarinnate Kunastitchai
    Department of Manufacturing Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
    Pharm Dev Technol 12:361-70. 2007
    The aerosol solvent extraction system (ASES) process was applied to prepare miconazole (MCZ) liposomes in a dry and reconstitutable form, the optimized temperature and pressure of which were 35 degrees C and 8.0 MPa, respectively...
  25. ncbi The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar cultures
    Alessandra Queiroga Gonçalves
    Laboratório de Doenças Parasitárias, Departamento de Medicina Tropical, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
    Rev Inst Med Trop Sao Paulo 49:201-2. 2007
    ..The present study reports on the excellent efficacy (100%) of the antifungal agent miconazole in eliminating B. hominis from cultures of E. histolytica/E...
  26. ncbi Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections
    E Ozyurt
    Onur Medical Research Ltd, Istanbul, Turkey
    Int J Gynaecol Obstet 74:35-43. 2001
    OBJECTIVE: To evaluate the efficacy of Neo-Penotran pessaries (metronidazole 500 mg + miconazole nitrate 100 mg) in candidal, bacterial and trichomonal vaginitis and in mixed vaginal infections...
  27. ncbi Lipid-covered drug particles: combined action of dioctadecyldimethylammonium bromide and amphotericin B or miconazole
    Nilton Lincopan
    , , , Avenida Lineu Prestes 748-Butant, CEP 05513-970, , Brazil
    J Antimicrob Chemother 58:66-75. 2006
    OBJECTIVES: Coverage of antifungal drug particles (miconazole and amphotericin B) with cationic lipid and evaluation of a synergistic action between lipid and drug...
  28. ncbi Miconazole: a historical perspective
    Annette W Fothergill
    Department of Pathology, University of Texas Health Science Center, San Antonio, TX 78229, USA
    Expert Rev Anti Infect Ther 4:171-5. 2006
    b>Miconazole is an imidazole that has been successfully used for over 30 years for the treatment of superficial and cutaneous disease. This agent is distinguished from other azoles by possessing two mechanisms of action...
  29. ncbi Dynamics of skin barrier repair following topical applications of miconazole nitrate
    E Xhauflaire-Uhoda
    Department of Dermatopathology, , , Belgium
    Skin Pharmacol Physiol 19:290-4. 2006
    ..Previous clinical studies have shown some inflammatory effect after topical applications of miconazole. The aim of this study was to compare the effect of pastes (petrolatum and 15% zinc oxide) containing or not ..
  30. ncbi Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing
    Noha A Nafee
    Department of Pharmaceutics, Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt
    Int J Pharm 264:1-14. 2003
    Mucoadhesive patches containing 10mg miconazole nitrate were evaluated...
  31. ncbi Preparation, characterization, and evaluation of miconazole-cyclodextrin complexes for improved oral and topical delivery
    S Tenjarla
    Department of Pharmaceutical Sciences, Mercer University, Atlanta, Georgia 30341, USA
    J Pharm Sci 87:425-9. 1998
    The solubility of miconazole in water increased in the presence of cyclodextrins (CDs)...
  32. ncbi Efficacy and tolerance of metronidazole and miconazole nitrate in treatment of vaginitis
    Fabio Peixoto
    Laboratory of Human Reproduction, Teaching Hospital, Federal University of Minas Gerais, Brazil
    Int J Gynaecol Obstet 102:287-92. 2008
    To evaluate the efficacy and tolerability of a vaginal pessary containing 750 mg of metronidazole and 200 mg of miconazole nitrate used daily for 7 days in the treatment of vaginitis.
  33. ncbi In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole
    Guo-Xian Wei
    Department of Oral Biology, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
    J Antimicrob Chemother 53:750-8. 2004
    ..of MUC7 12-mer in combination with other compounds [histatin-5 (Hsn5) 12-mer: AKRHHGYKRKFH, amphotericin B or miconazole] against C. albicans and C. neoformans were determined by chequerboard assays and confirmed by killing assays...
  34. ncbi Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model
    R A Lubet
    National Cancer Institute, Division of Cancer Prevention and Control, Bethesda, MD, USA
    Int J Cancer 72:95-101. 1997
    The chemopreventive efficacy of N-acetyl-L-cysteine (NAC), anethole trithione, miconazole and phenethylisothiocyanate (PEITC), each of which would be expected to alter carcinogen metabolism, was examined in the dimethylbenzanthracene (..
  35. ncbi Effect of acidic ternary compounds on the formation of miconazole/cyclodextrin inclusion complexes by means of supercritical carbon dioxide
    Valery Barillaro
    Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Liege, CHU Tour 4, Bat B36, Avenue de l Hopital, 1, 4000 Liege 1, Belgium
    J Pharm Pharm Sci 7:378-88. 2004
    The aim of the study is to evaluate the effect of different acidic compounds on the inclusion of miconazole (MICO) in several cyclodextrins (CDs) using supercritical carbon dioxide (SCCO(2) ) processing.
  36. ncbi Swelling-controlled release system for the vaginal delivery of miconazole
    T K Mandal
    Division of Pharmaceutics, College of Pharmacy, Xavier University of Louisiana, New Orleans LA 70125, USA
    Eur J Pharm Biopharm 50:337-43. 2000
    b>Miconazole nitrate, a fungicidal, is effective for the local treatment of vaginitis. The objective of this project was to develop a swelling-controlled release delivery system for miconazole...
  37. ncbi The effects of amphotericin B, fluconazole and miconazole on neutrophil and lymphocyte function in a guinea pig model
    D C Drummond
    University of Queensland, Department of Medicine and Infectious Diseases, Mater Misericordiae Hospital, South Brisbane, Australia
    J Antimicrob Chemother 36:375-84. 1995
    We studied the effects of amphotericin B, fluconazole and miconazole on guinea pig neutrophil and lymphocyte function. Neutrophil adherence, chemotaxis, and deoxyglucose uptake and mitogen-induced lymphocyte proliferation were examined...
  38. ncbi New beauvericins, potentiators of antifungal miconazole activity, Produced by Beauveria sp. FKI-1366. I. Taxonomy, fermentation, isolation and biological properties
    Takashi Fukuda
    Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
    J Antibiot (Tokyo) 57:110-6. 2004
    ..FKI-1366 by solvent extraction, ODS column chromatography and HPLC. These compounds potentiate miconazole activity against not only wild Candida albicans but also fluconazole resistant C. albicans...
  39. ncbi In vitro antifungal susceptibility of Candida spp. isolates from patients with chronic periodontitis and from control patients
    Cristiane Yumi Koga Ito
    Department of Biosciences and Oral Diagnosis, ,
    Braz Oral Res 18:80-4. 2004
    ..glabrata was resistant to ketoconazole and 1 Candida spp. was resistant to amphotericin B, ketoconazole and miconazole. Among the isolates of periodontitis group, 1 (3.33%) C...
  40. ncbi Minimum inhibitory concentration of adherence of Punica granatum Linn (pomegranate) gel against S. mutans, S. mitis and C. albicans
    Laurylene César de Souza Vasconcelos
    Departament of Clinical and Social Dentistry, Federal University of Paraiba, Joao Pessoa, PB, Brazil
    Braz Dent J 17:223-7. 2006
    ..was to investigate the antimicrobial effect of a Punica granatum Linn (pomegranate) phytotherapeutic gel and miconazole (Daktarin oral gel) against three standard streptococci strains (mutans ATCC 25175, sanguis ATCC 10577 and mitis ..
  41. ncbi Anticandidial activity of some essential oils of a mega biodiversity hotspot in India
    B K Dutta
    Biotechnology Division, Defence Research Laboratory, Tezpur, Assam, India
    Mycoses 50:121-4. 2007
    ..Callistemon lanceolatus, Cinnamomum camphora, Citrus limon, Tagetes petula, as well as two standard antibiotics, miconazole and clotrimazole, were tested in vitro for their anticandidial activity...
  42. ncbi Synthesis, antifungal activity, and structure-activity relationships of coruscanone A analogues
    K Suresh Babu
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences and Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA
    J Med Chem 49:7877-86. 2006
    ....
  43. ncbi Azole therapy of clinical and experimental coccidioidomycosis
    David A Stevens
    Department of Medicine, Santa Clara Valley Medical Center, 751 So Bascom Avenue, San Jose, CA 95128 2699, USA
    Ann N Y Acad Sci 1111:442-54. 2007
    ..advances in the pharmacologic and antimicrobial properties of this class since the initial introduction of miconazole, and many patients with coccidioidomycosis have benefited...
  44. ncbi Patterns of antifungal prescribing in general dental practice
    R J Oliver
    Oral and Maxillofacial Surgery, University Dental Hospital of Manchester
    Br Dent J 196:701-3; discussion 687; quiz 707. 2004
    ..To examine the current practice of antifungal prescribing by GDPs in the United Kingdom. Design A postal questionnaire circulated to a random selection of 400 dentists...
  45. ncbi In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis
    A J Carrillo-Munoz
    Departamento de Microbiologia, Asesoria, Cientifica y de la Investigación Aplicada, Hospital Vall d Hebron, Barcelona, Espana
    Chemotherapy 50:308-13. 2004
    ..21-74 h). The antifungals used are itraconazole, ketoconazole, miconazole, clotrimazole, sertaconazole, terbinafine, tioconazole, fluconazole, isoconazole and econazole...
  46. ncbi [Antifungal susceptibility among the isolates of yeast from the University Hospital of the Ryukyus]
    Chiaki Ohta
    Clinical Laboratories, University Hospital of the Ryukyus, Nishihara, Nakagami Okinawa
    Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 16:127-33. 2005
    ..tropicalis and C. glabrata were estimated as being 40.6% and 13.7%, respectively. The activities of miconazole and micafungin were the most potent with MICs50, 0.125 and 0.06 microg/ml. However, the MICs of C...
  47. ncbi Antifungal susceptibility of epigallocatechin 3-O-gallate (EGCg) on clinical isolates of pathogenic yeasts
    Bong Joo Park
    The United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1193, Japan
    Biochem Biophys Res Commun 347:401-5. 2006
    ..agents, amphotericin B (AMPH), fluconazole (FLCZ), flucytosin (5FC), itraconazole (ITCZ), micafungin (MCFG), and miconazole (MCZ), using a method following the National Committee for Clinical Laboratory Standards (NCCLS) M27-A ..
  48. ncbi Comparison of an antifungal agent with a mixture of antifungal, antibiotic and corticosteroid agents for the treatment of Malassezia species otitis in dogs
    E Bensignor
    Dermatology Referral Service, , , France
    Vet Rec 158:193-5. 2006
    ..clotrimazole, marbofloxacin and dexamethasone, and in the other ear with a topical antifungal containing miconazole. The effects of the treatments were analysed on the basis of the scores for pruritus, erythema and amount of ..
  49. ncbi Modification of the fluorescein diacetate assay for screening of antifungal agents against Candida albicans: comparison with the NCCLS methods
    Nynke Brouwer
    Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia
    J Microbiol Methods 66:234-41. 2006
    ..1%, 0.1% and 1% w/v, respectively) and buffered with 10 mM BES buffer. The MICs of amphotericin B, fluconazole, miconazole and flucytosine (representing three major classes of antifungal agents) obtained by the three methods were ..
  50. ncbi [The comparison of susceptibility of Candida albicans and Candida glabrata to miconazole]
    P Kurnatowski
    , ,
    Wiad Parazytol 47:867-73. 2001
    ..strains isolated from patietnts treated in Centre for Treatment of Parasitic Diseases and Mycoses - to miconazole using MIC. 96.5% of strains were sensitive to miconazole; values of MIC for C. albicans were lower than for C...
  51. ncbi [Antifungal susceptibility of clinically isolated Candida albicans by broth microdilution method]
    T Yamazumi
    Department of Clinical Pathology, Kinki University School of Medicine
    Kansenshogaku Zasshi 72:813-9. 1998
    ..The antifungal agents tested were fluconazole, miconazole, intraconazole, amphotericin B and flucytosine...
  52. ncbi In vitro susceptibility of oral Candida to seven antifungal agents
    T Kuriyama
    Department of Oral Surgery, Medicine and Pathology, School of Dentistry, Cardiff University, Cardiff, UK
    Oral Microbiol Immunol 20:349-53. 2005
    The in vitro susceptibility of 618 Candida isolates to fluconazole, itraconazole, voriconazole, ketoconazole, miconazole, amphotericin B, and nystatin was determined...
  53. ncbi Synthesis and antifungal activity of oxygenated cholesterol derivatives
    Jean Michel Brunel
    Laboratoire Synthèse et Etude de Substances Naturelles à Activités Biologiques SESNAB, IMRN INRA 1111, Faculté des Sciences et Techniques de St Jérôme, Universite Paul Cezanne, Aix Marseille III, 13397 Marseille Cedex 20, France
    Steroids 70:907-12. 2005
    ..For example, compound 2 exhibited high activities against C. albicans (CIP 1663-86) and Amphotericine B and miconazole resistant strain C. albicans (CIP 1180-79) at a concentration of 1.5 microg/mL.
  54. ncbi [Susceptibility to itraconazole and miconazole of fungi strains isolated from the vaginal ontocenosis]
    A Kurnatowska
    Katedra Biologii i Parazytologii Lekarskiej, , ,
    Wiad Parazytol 47:131-5. 2001
    The activity of itraconazole (RO 51211, molecular weight 705,64) and miconazole (RO 14889, molecular weight 479,15) obtained from Janssen Pharmaceutica NV, against 100 fungi strains, was studied...
  55. ncbi Citridones, new potentiators of antifungal miconazole activity, produced by Penicillium sp. FKI-1938. I. Taxonomy, fermentation, isolation and biological properties
    Takashi Fukuda
    Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
    J Antibiot (Tokyo) 58:309-14. 2005
    ..Citridones (75 microM) potentiate the miconazole activity against Candida albicans, decreasing the IC50 value of miconazole from 14.5 nM to 3...
  56. ncbi Phenatic acids A and B, new potentiators of antifungal miconazole activity produced by Streptomyces sp. K03-0132
    Takashi Fukuda
    Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
    J Antibiot (Tokyo) 58:252-9. 2005
    ..They have a common 1-hydroxy 2, 4-dimethyl benzene ring. These compounds potentiate miconazole activity against Candida albicans...
  57. ncbi Determination of the absolute configuration and solution conformation of the antifungal agents ketoconazole, itraconazole, and miconazole with vibrational circular dichroism
    David Dunmire
    Department of Chemistry, Syracuse University, Syracuse, New York 13244-4100, USA
    Chirality 17:S101-8. 2005
    ..2R,4S)-ketoconazole, (+)-(2R,4S)-itraconazole (with (S)-configuration at the sec-butyl group) and (+)-(S)-miconazole nitrate have been confirmed by using vibrational circular dichroism (VCD)...
  58. ncbi MgMfs1, a major facilitator superfamily transporter from the fungal wheat pathogen Mycosphaerella graminicola, is a strong protectant against natural toxic compounds and fungicides
    Ramin Roohparvar
    Laboratory of Phytopathology, Wageningen University, P O Box 8025, 6700 EE Wageningen, The Netherlands
    Fungal Genet Biol 44:378-88. 2007
    ..The results indicate that MgMfs1 is a true multidrug transporter that can function as a determinant of pathogen sensitivity and resistance to fungal toxins and fungicides...
  59. ncbi Successful treatment of Paecilomyces lilacinus keratitis in a patient with a history of herpes simplex virus keratitis
    Monika A Malecha
    Department of Ophthalmology, University of Missouri, Kansas City and Eye Foundation of Kansas City, Kansas City, MO 64108, USA
    Cornea 25:1240-2. 2006
    ..To report a case of Paecilomyces lilacinus keratitis, initially misdiagnosed as Penicillium sp., in a patient with a long-standing history of herpes simplex virus (HSV) keratitis...
  60. ncbi Feasibility of using collagen as the base of the antifungal drug, miconazole
    K Yoshida
    Department of Removable Prosthodontics, Matsumoto Dental University, Nagano, Japan
    J Oral Rehabil 33:363-7. 2006
    The feasibility of using collagen as the base of miconazole was investigated...
  61. ncbi Modulation of human T-lymphocyte plasma membrane Ca2+ permeability by imidazole antimycotics
    E H Hornstein
    Department of Clinical Investigation, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA
    Immunopharmacol Immunotoxicol 18:237-45. 1996
    ..Econazole, miconazole and clotrimazole dramatically inhibited the THG mediated increase in [Ca+2]i and induced an increase in [Ca+2]i ..
  62. ncbi [Case of sycosis candidiasis on the upper lip]
    Yuki Kitami
    Department of Dermatology, Showa University School of Medicine, Tokyo, Japan
    Nihon Ishinkin Gakkai Zasshi 49:81-6. 2008
    ..He was successfully treated with 2 courses of pulse therapy of oral itraconazole for sycosis candidiasis, accompanied by 2% miconazole gel for oral candidiasis.
  63. ncbi [Treatment of fungal infections of upper respiratory tract and ear]
    Piotr Kurnatowski
    Katedra Biologii i Genetyki Medycznej, Zakład Biologii i Parazytologii Lekarskiej Uniwersytetu Medycznego w Lodzi
    Otolaryngol Pol 61:280-5. 2007
    ..lozenges include amphotericin B, clotrimazole, chlorhexidine or chlorquinaldol and oral gels: nystatin and miconazole. Some of drugs are in the form of suspension/solution, which can be used for inhalation, into the sinus, for ..
  64. ncbi Funicone-related compounds, potentiators of antifungal miconazole activity, produced by Talaromycesflavus FKI-0076
    Masayoshi Arai
    Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan
    J Antibiot (Tokyo) 55:172-80. 2002
    ..FKI-0076, a soil isolate, was found to produce compounds which reinforce the anti-Candida albicans activity of miconazole. Four structurally related compounds, a novel one, designated actofunicone, and the knowns deoxyfunicone, ..
  65. ncbi Effect of antifungal azoles on the heme detoxification system of malarial parasite
    Nguyen Tien Huy
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan
    J Biochem (Tokyo) 131:437-44. 2002
    The antimalarial activities of some antifungal azole agents (ketoconazole, miconazole, and clotrimazole) have been known for several years, however, their antimalarial mechanism remains equivocal...
  66. ncbi [Vaginal candidiasis: etiology and sensitivity profile to antifungal agents in clinical use]
    A M Saporiti
    , , La Plata, Pcia. de Buenos Aires, Argentina
    Rev Argent Microbiol 33:217-22. 2001
    ..Fluconazole resistant C. albicans were isolated in 13.46% of the cases. Thus, further studies are required to correlate the possible role of these strains in recurrent vulvovaginal candidiasis...
  67. ncbi In vitro activities of 10 antifungal drugs against 508 dermatophyte strains
    B Fernandez-Torres
    Unitat de Microbiologia, Facultat de Medicina and Institut d Estudis Avançats, Universitat Rovira i Virgili, Reus, Spain
    Antimicrob Agents Chemother 45:2524-8. 2001
    ..The antifungals used were itraconazole, ketoconazole, miconazole, clotrimazole, voriconazole, terbinafine, amphotericin B, fluconazole, UR-9825, and G-1...
  68. ncbi In vitro efficacy of a buffered chelating solution as an antimicrobial potentiator for antifungal drugs against fungal pathogens obtained from horses with mycotic keratitis
    William L Weinstein
    Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Am J Vet Res 67:562-8. 2006
    ..PROCEDURE: Minimum inhibitory concentrations (MICs) against fungal isolates for 4 antifungal drugs (miconazole, ketoconazole, itraconazole, and natamycin) were compared with MICs against fungal isolates for the combinations ..
  69. ncbi Diaper dermatitis: a therapeutic dilemma. Results of a double-blind placebo controlled trial of miconazole nitrate 0.25%
    P Concannon
    Royal North Shore Hospital, St. Leonards, New South Wales, Australia
    Pediatr Dermatol 18:149-55. 2001
    ..This placebo-controlled, randomized, double-blind, parallel-group trial compared the efficacy and safety of miconazole nitrate 0...
  70. ncbi Balanitis with eczematous perigenital intertriginous candidosis
    Hans Jürgen Tietz
    Institut für Pilzkrankheiten, Luisenstr, Berlin, Germany
    Mycoses 51:46-7. 2008
  71. ncbi Comparison of in vitro activities of amphotericin, clotrimazole, econazole, miconazole, and nystatin against Fusarium oxysporum
    M N Tzatzarakis
    Department of Medicine, University of Crete, Heraklion, Greece
    J Environ Sci Health B 36:331-40. 2001
    The inhibitory activity of amphotericin B, clotrimazole, econazole, miconazole and nystatin was compared against Fusarium oxysporum f.sp. radicis-cucumerinum...
  72. ncbi [Evaluation of effective treatment drugs against Acanthamoeba cyst]
    K Tahara
    Clinical Laboratory, Osaka University Hospital
    Kansenshogaku Zasshi 71:1025-30. 1997
    ..confirmed Acanthamoeba keratitis were tested in vitro for sensitivity to antimycotic agents such as fluconazole, miconazole, amphotericin-B, pimaricin, antiprotozoal agents such as pentamidine isetionate and antiseptics which could be ..
  73. ncbi Antifungal drug susceptibilities of commensal Candida isolates
    Ann R Holmes
    Department of Oral Sciences and Orthodontics, School of Dentistry, University of Otago, PO Box 647, Dunedin
    N Z Dent J 98:36-9. 2002
    ..broth microdilution method for susceptibility to fluconazole and to a related over-the-counter azole antifungal, miconazole. A positive correlation between susceptibility to fluconazole and to miconazole was observed...
  74. ncbi Colonization of voice prostheses by albicans and non-albicans Candida species
    Tiene G M Bauters
    Department of Pharmaceutical Analysis, Ghent University, Belgium
    Laryngoscope 112:708-12. 2002
    ..e., miconazole, fluconazole, and nystatin)...
  75. ncbi Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects
    H Vanden Bossche
    Steenweg op Gierle 68, B 2300 Turnhout, Belgium
    J Vet Pharmacol Ther 26:5-29. 2003
    ..This review includes chemical aspects, spectra of activity, mechanisms of action and resistance, adverse reactions and drug interactions of the antifungals in current use...
  76. ncbi [Present status and future prospects of azole antifungal agents in Japan]
    Katsuhiko Kamei
    Jpn J Antibiot 55:907-10. 2002
  77. ncbi SRE1 and SRE2 are two specific steroid-responsive modules of Candida drug resistance gene 1 (CDR1) promoter
    Neerja Karnani
    School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
    Yeast 21:219-39. 2004
    ..Both SRE1 and SRE2 were specific for steroids, as they did not respond to other drugs, such as cycloheximide, miconazole and terbinafine...
  78. ncbi Deep fungal dermatitis in three inland bearded dragons (Pogona vitticeps) caused by the Chrysosporium anamorph of Nannizziopsis vriesii
    Michelle R Bowman
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, USA
    Med Mycol 45:371-6. 2007
    ..This lizard died while undergoing itraconazole and topical miconazole therapy...
  79. ncbi Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections
    Valda Teixeira Figueiredo
    Departamento de Microbiologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, PO Box 486, 31270 901 Belo Horizonte, MG, Brazil
    Mycopathologia 164:27-33. 2007
    ..With azoles, lower percentages of agreement between the methodologies were observed for samples C. albicans and C. tropicalis...
  80. ncbi Experimental evaluation of antifungal and antiseptic agents against Rhodotorula spp
    L Preney
    Laboratoire de Parasitologie Mycologie, Centre Hospitalier Universitaire, Rennes, France
    Mycoses 46:492-5. 2003
    ..amphotericin B, and nystatin, intermediate to econazole and resistant to fluconazole, itraconazole and miconazole. After 5-min contact, six of the eight antiseptic agents tested showed a fungicidal activity on the tested R...
  81. ncbi In vitro activities of the new antifungal drug eberconazole and three other topical agents against 200 strains of dermatophytes
    Belkys Fernández-Torres
    Unitat de Microbiologia, Facultat de Medicina i Ciencies de la Salut, Universitat Rovira i Virgili, 43201 Reus, Spain
    J Clin Microbiol 41:5209-11. 2003
    ..drug eberconazole with those of three other topical antifungal agents, clotrimazole, ketoconazole, and miconazole, against 200 strains of dermatophytes...
  82. ncbi Effects of cytochrome P450 inhibitors on agonist-induced Ca2+ responses and production of NO and PGI2 in vascular endothelial cells
    Kazuhiko Takeuchi
    Department of Internal Medicine III, Hamamatsu University School of Medicine, Handayama, Hamamatsu, Japan
    Mol Cell Biochem 248:129-34. 2003
    ..To this end, structurally different CYP inhibitors including SKF 525A, econazole and miconazole were tested on primary cultured porcine aortic endothelial cells...
  83. ncbi [The problem of otomycosis treatment]
    M I Kurdina
    Voen Med Zh 324:49-51. 2003
  84. ncbi Pathogenic Nocardia, Rhodococcus, and related organisms are highly susceptible to imidazole antifungals
    Eric R Dabbs
    School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg, South Africa
    Antimicrob Agents Chemother 47:1476-8. 2003
    ..from closely related genera, are highly susceptible to the imidazoles bifonazole, clotrimazole, econazole, and miconazole, whose MICs are </=1 micro g/ml...
  85. ncbi Strategy for the development of automated methods involving dialysis and trace enrichment as on-line sample preparation for the determination of basic drugs in plasma by liquid chromatography
    P Chiap
    Department of Analytical Pharmaceutical Chemistry, Institute of Pharmacy, , Avenue de l'Hopital 1, CHU-B36, , Belgium
    J Chromatogr A 948:151-61. 2002
    ..of this method development strategy, an automated procedure based on the coupling of dialysis with trace enrichment has been developed for the LC determination of antifungal agents (clotrimazole, econazole and miconazole) in plasma.
  86. ncbi Sertaconazole: a review of its use in the management of superficial mycoses in dermatology and gynaecology
    Jamie D Croxtall
    Wolters Kluwer Health Adis, Auckland, New Zealand
    Drugs 69:339-59. 2009
    ..dermatophytoses, and a significantly greater proportion of patients were cured compared with those receiving 2% miconazole cream twice-daily treatment...
  87. ncbi Terbinafine. An update of its use in superficial mycoses
    K J McClellan
    Adis International Limited, Auckland, New Zealand
    Drugs 58:179-202. 1999
    ..Its formulations are at least as effective as miconazole 2% cream and naftifine 1% gel in tinea pedis, and more effective than clotrimazole 1% cream, bifonazole 1% cream ..
  88. ncbi Opportunistic amoebae: challenges in prophylaxis and treatment
    Frederick L Schuster
    Viral and Rickettsial Disease Laboratory, California Department of Health Services, Richmond, CA 94804, USA
    Drug Resist Updat 7:41-51. 2004
    ..more or less successfully, with antimicrobial combinations including sterol-targeting azoles (clotrimazole, miconazole, ketoconazole, fluconazole, itraconazole), pentamidine isethionate, 5-fluorocytosine, and sulfadiazine...
  89. ncbi Anti-mycotics suppress interleukin-4 and interleukin-5 production in anti-CD3 plus anti-CD28-stimulated T cells from patients with atopic dermatitis
    N Kanda
    Department of Dermatology, Teikyo University, School of Medicine, Japan
    J Invest Dermatol 117:1635-46. 2001
    ..Azole derivatives, ketoconazole, itraconazole, miconazole, and nonazole terbinafine hydrochloride, and tolnaftate reduced interleukin-4 and interleukin-5 secretion ..
  90. ncbi Topical fenticonazole in dermatology and gynaecology: current role in therapy
    Stefano Veraldi
    Institute of Dermatological Sciences, University of Milan, Milan, Italy
    Drugs 68:2183-94. 2008
    ..show fenticonazole once or twice daily to be at least as effective as six different topical antimycotics (miconazole, clotrimazole, econazole, bifonazole, naftifine and cyclopyroxolamine) in the treatment of superficial mycoses ..
  91. ncbi Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1
    D D Surry
    Department of Drug Metabolism and Pharmacokinetics, Merck Research Laboratories, Harlow, UK
    Xenobiotica 30:441-56. 2000
    ..In the CYP3A RHIP assay, pregnenalone 16alpha-carbonitrile (PCN), DEX, clotrimazole (CLOT) and miconazole (MIC) were all good inducers of CYP3A mRNA; beta-napthoflavone (BNF) and methylclofenapate (MCP), however, did ..
  92. ncbi [Use of topical antifungal agents]
    Bertrand Dupont
    Maladies Infectieuses et Tropicales, Universite Paris 5, Hopital Necker Enfants Malades, Paris, France
    Therapie 61:251-4. 2006
    ..is based on topical antifungal agents: amphotericin B or nystatin, imidazoles such as clotrimazole or miconazole. Systemic antifungal agents are indicated in case or poor compliance to topical agents, in prophylaxis of highly ..
  93. ncbi In vitro susceptibility patterns of Aspergillus and Fusarium species isolated from equine ulcerative keratomycosis cases in the midwestern and southern United States with inclusion of the new antifungal agent voriconazole
    Jacqueline W Pearce
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri Columbia, Columbia, MO 65211, USA
    Vet Ophthalmol 12:318-24. 2009
    ..isolated from horses with ulcerative keratomycosis, address regional differences in equine keratomycosis isolates, and provide susceptibility data to update prior studies...
  94. ncbi In vitro activity of 6 antifungal agents on candida species isolated as causative agents from vaginal and other clinical specimens
    M S Ellabib
    Department of Medical Microbiology, Faculty of Medicine, Al Fateh University, PO Box 13497, Tripoli, Libya
    Saudi Med J 22:860-3. 2001
    ..To study the susceptibility pattern of candida species isolated from various clinical specimens to common usable antifungals in Libya...
  95. ncbi Prediction of the metabolic interaction of nateglinide with other drugs based on in vitro studies
    Toshiyuki Takanohashi
    Pharmaceutical Company, Ajinomoto Co, Inc, Kawasaki ku, Kawasaki, Japan
    Drug Metab Pharmacokinet 22:409-18. 2007
    ..gliclazide, clofibrate, fluconazole, bezafibrate, phenylbutazone, nifedipine, famotidine, ibuprofen and miconazole) on the conversion of nateglinide to its major metabolite (N-[trans-4-(1-hydroxy-1-methylethyl)-..
  96. ncbi The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity
    J Bełtowski
    Department of Pathophysiology, Medical University, Lublin, Poland
    J Physiol Pharmacol 53:211-31. 2002
    ..inhibitors of cytochrome P450-dependent arachidonate metabolism, whereas an inhibitor of epoxygenase, miconazole, was not effective...
  97. ncbi Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles
    Eva R Trösken
    Department of Toxicology, University of Wurzburg, Versbacher Str 9, Wurzburg, Germany
    Toxicology 228:24-32. 2006
    ..inhibition (> or = 30 microM) while the older drugs were even more potent than the agricultural fungicides, with miconazole being the most potent (0.057 microM)...
  98. ncbi Candidemia and the susceptibility pattern of Candida isolates in blood
    Abimbola O Osoba
    Division of Microbiology, King Khalid National Guard Hospital, Jeddah, Kingdom of Saudi Arabia
    Saudi Med J 24:1060-3. 2003
    ..The purpose of our study was to determine the prevalence of Candida species among our bloodstream infecting organisms and the susceptibility pattern of the Candida isolates to antifungal agents...
  99. ncbi What defines the quality of patient care in tinea pedis?
    S Mistik
    Department of Family Medicine, Erciyes University Medical Faculty, Kayseri, Turkey
    J Eur Acad Dermatol Venereol 20:158-65. 2006
    ....
  100. ncbi The effects by neuroleptics, antimycotics and antibiotics on disulfide reducing enzymes from the human pathogens Acanthamoeba polyphaga and Naegleria fowleri
    RAUL N ONDARZA
    Center of Research on Infectious Diseases, National Institute of Public Health, Cuernavaca, Mor 62508, Mexico
    Exp Parasitol 115:41-7. 2007
    ..two neuroleptic agents, chlorpromazine and trifluoperazine; three antimycotics, amphotericin B, ketoconazole and miconazole and four antibiotics, pentamidine, rifampicin, mepacrine and metronidazole on the NADPH-dependent disulfide ..
  101. ncbi In vitro antiproliferative effects of neuroleptics, antimycotics and antibiotics on the human pathogens Acanthamoeba polyphaga and Naegleria fowleri
    RAUL N ONDARZA
    Center for Research on Infectious Diseases, National Institute of Public Health, Cuernavaca, Morelos, Mexico
    Arch Med Res 37:723-9. 2006
    ....

Research Grants79

  1. ANTIFUNGAL RESPONSE--MDR INDUCTION
    Thomas Edlind; Fiscal Year: 2002
    ..Candida albicans, Candida krusei, or Saccharomyces cerevisiae to certain drugs (including the antifungal azoles miconazole and clotrimazole, the benzimidazole albendazole, and sulfadiazine) induced a 3 to > 10-fold increase in mRNAs ..
  2. Estrogen and brain vascular inflammation in diabetics
    Dale Pelligrino; Fiscal Year: 2007
    ..The results of these studies will permit us to gain an understanding of some of the mechanisms behind estrogen's conversion to the "dark side" and should lead to improvements in the clinical efficacy of hormone replacement treatments. ..
  3. TEXAS SOUTHERN UNIVERSITY RESEARCH SCIENTIST AWARD
    Adebayo Oyekan; Fiscal Year: 2007
    ....
  4. 20-HETE IN NO-MEDIATED REGULATION OF RENAL FUNCTION
    Adebayo Oyekan; Fiscal Year: 2001
    ....
  5. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt Barnhart; Fiscal Year: 2007
    ....
  6. CANDIDACIDAL MECHANISMS OF SALIVARY HISTATINS
    Mira Edgerton; Fiscal Year: 2007
    ..albicans microarray analysis. An understanding of the mechanism of Hst 5-induced killing and the nature of its specificity for yeast cells over human cells will contribute to future development of improved antifungal drugs. ..
  7. HISTAMINERGIC MECHANISMS OF ANTINOCICEPTION
    LINDSAY HOUGH; Fiscal Year: 2007
    ..These collaborative experiments between pharmacologists, neurophysiologists and chemists will discover the mechanism of action of this novel class of agents and lead to the development of new, non-opioid pharmacotherapies for pain. ..
  8. Estrogen and EDHF in NO Deficiency
    An Huang; Fiscal Year: 2006
    ..The knowledge generated by these studies will unravel the roles of estrogen in the regulation of arteriolar function related specifically to the involvement of EDHF-mediated dilator pathways in adaptation to NO deficiency. ..
  9. P450 Epoxygenase Mechanisms of Opioid Analgesia
    LINDSAY HOUGH; Fiscal Year: 2010
    ..This proposal will uncover new biochemical mechanisms for pain relief, and test a new group of chemicals for pain-relieving properties. This research could lead to the development of new, non-addicting pain relievers. ..
  10. Estrogen and EDHF in NO Deficiency
    An Huang; Fiscal Year: 2010
    ..Thus, this project is to study how endothelial cells release the agents when stimulated with estrogen and shear stress. ..
  11. CANDIDACIDAL MECHANISMS OF SALIVARY HISTATINS
    Mira Edgerton; Fiscal Year: 2009
    ..albicans. The proposed experiments will be accomplished during the final year of the parent grant and accelerate the tempo of our research by generating new data for additional publications and a new research project. ..
  12. Astrocytes and neurovascular coupling
    Dale Pelligrino; Fiscal Year: 2009
    ..The central hypothesis is that astrocytes and the glia limitans represent a vital signaling conduit in the pial arteriolar dilation arising from neural activation. ..
  13. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt T Barnhart; Fiscal Year: 2010
    ....
  14. Vascular adhesion protein-1 (VAP-1) as a therapeutic target in stroke
    DALE ALAN PELLIGRINO; Fiscal Year: 2010
    ..The present project utilizes a selective pharmacologic approach that targets a novel protein which appears to be important in the trafficking of all leukocyte subsets and, therefore, may prove to have wide-ranging clinical efficacy. ..
  15. NITRIC OXIDE AND IN VIVO BRAIN ARTERIOLAR RELAXATION
    Dale Pelligrino; Fiscal Year: 1999
    ....
  16. HISTAMINERGIC MECHANISMS OF ANTINOCICEPTION
    LINDSAY HOUGH; Fiscal Year: 1999
    ..These studies will clarify the mechanisms by which MOR relieves pain, enhance the understanding of histaminergic antinociceptive mechanisms, and may lead to the discovery of non-addicting, novel medications for the treatment of pain. ..
  17. HISTAMINERGIC MECHANISMS OF ANALGESIA
    LINDSAY HOUGH; Fiscal Year: 1992
    ..These studies will enhance our knowledge of antinociceptive mechanisms, and may lead to the development of novel, clinically useful agents for the relief of pain...
  18. HISTATIN RECEPTORS AS DRUG TARGETS FOR ORAL CANDIDIASIS
    Mira Edgerton; Fiscal Year: 2003
    ..This award would provide her the opportunity to extend her background in yeast biology to the molecular level and apply this new expertise to studies of virulence and pathogenesis of oral and systemic candidiasis. ..
  19. HISTAMINERGIC MECHANISMS OF ANTINOCICEPTION
    LINDSAY HOUGH; Fiscal Year: 2003
    ....
  20. CANDIDACIDAL MECHANISMS OF SALIVARY HISTATINS
    Mira Edgerton; Fiscal Year: 2003
    ..These studies will contribute to characterization of novel intracellular pathways utilized by Hst to cause yeast cell death and lead to further understanding of the role of ATP efflux as a cell regulatory or signaling process. ..
  21. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt Barnhart; Fiscal Year: 2003
    ..abstract_text> ..
  22. Astrocytes and neurovascular coupling
    DALE ALAN PELLIGRINO; Fiscal Year: 2010
    ..The central hypothesis is that astrocytes and the glia limitans represent a vital signaling conduit in the pial arteriolar dilation arising from neural activation. ..
  23. CANDIDACIDAL MECHANISMS OF SALIVARY HISTATINS
    Mira Edgerton; Fiscal Year: 2010
    ..Objectives of this proposal are to design salt-insensitive peptides that selectively target yeast cells as oral therapeutic agents for candidiasis. ..
  24. Nikkomycin Z Treatment for Coccidioidomycosis
    John Galgiani; Fiscal Year: 2006
    ..By carrying out the proposed work, we will resume the clinical development of nikkomycin Z as a potentially curative therapy for coccidioidomycosis so that it may become a candidate for final commercial development. ..
  25. NITRIC OXIDE AND IN VIVO BRAIN ARTERIOLAR RELAXATION
    Dale Pelligrino; Fiscal Year: 2004
    ..These studies will provide important new information regarding the mechanisms controlling a physiologic process vital to normal brain function and survival-cerebral arteriolar dilation. ..