amylases

Summary

Summary: A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.

Top Publications

  1. ncbi Alcohol-induced protein kinase Calpha phosphorylation of Munc18c in carbachol-stimulated acini causes basolateral exocytosis
    Laura I Cosen-Binker
    Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Gastroenterology 132:1527-45. 2007
  2. ncbi Low serum amylase levels in drinking alcoholics
    Katsuya Maruyama
    Department of Internal Medicine, National Alcoholism Center, Kurihama Hospital, Yokosuka, Kanagawa, Japan
    Alcohol Clin Exp Res 27:16S-21S. 2003
  3. ncbi The islet-acinar axis of the pancreas: more than just insulin
    Savio G Barreto
    Department of General and Digestive Surgery, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia 5042
    Am J Physiol Gastrointest Liver Physiol 299:G10-22. 2010
  4. ncbi Biochemical analysis of serum pancreatic amylase and lipase enzymes in patients with type 1 and type 2 diabetes mellitus
    Adib A Aughsteen
    Faculty of Pharmacy, Al Zaytoonah University, PO Box 130, Amman 11733, Jordan
    Saudi Med J 26:73-7. 2005
  5. ncbi Secretin-stimulated amylase release into blood is impaired in type 1 diabetes mellitus
    A Swislocki
    Section of Endocrinology, Medical Service, Veterans Affairs Medical Center, Martinez, California 94553, USA
    Horm Metab Res 37:326-30. 2005
  6. ncbi Mice lacking the transcription factor Mist1 exhibit an altered stress response and increased sensitivity to caerulein-induced pancreatitis
    Agnes S Kowalik
    Department of Physiology, The University of Western Ontario, London, Ontario, Canada
    Am J Physiol Gastrointest Liver Physiol 292:G1123-32. 2007
  7. ncbi Bacterial diversity and bioprospecting for cold-active lipases, amylases and proteases, from culturable bacteria of kongsfjorden and Ny-alesund, Svalbard, Arctic
    T N R Srinivas
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, 500 007, India
    Curr Microbiol 59:537-47. 2009
  8. ncbi Use of mesophilic fungal amylases produced by solid-state fermentation in the cold hydrolysis of raw babassu cake starch
    Aline Machado de Castro
    Research and Development Center, Renewable Energy Division, PETROBRAS, Av Horácio Macedo, 950 Ilha do Fundão, Rio de Janeiro, Brazil
    Appl Biochem Biotechnol 162:1612-25. 2010
  9. ncbi Attenuated cerulein-induced pancreatitis in nuclear factor-kappaB-deficient mice
    Domenica Altavilla
    Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Italy
    Lab Invest 83:1723-32. 2003
  10. ncbi Compartmentalization of proteinases and amylases in Nauphoeta cinerea midgut
    E N Elpidina
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, Moscow, Russia
    Arch Insect Biochem Physiol 48:206-16. 2001

Research Grants

  1. Self-Regulation as a Biological Mechanism for Excess Weight Gain in Toddlers
    Alison L Miller; Fiscal Year: 2010
  2. GENETIC COMPETENCE IN STREPTOCCUS MUTANS BIOFILMS
    Dennis Cvitkovitch; Fiscal Year: 2001
  3. The Course of Regulation and Dysregulation in Children
    TRACY LORRAINE SPINRAD; Fiscal Year: 2010
  4. The Course of Regulation and Dysregulation in Children
    Nancy Eisenberg; Fiscal Year: 2009
  5. IN VIVO STUDIES OF SALIVA ANTIMICROBIAL PROTEINS
    JOEL RUDNEY; Fiscal Year: 2001
  6. NOVEL PROTEASE FORMULATION BASED ON CROSSLINKED CRYSTALS
    Bhami Shenoy; Fiscal Year: 2004
  7. Poverty, Stress, and Discounting: A potential micro-mechanism for behavior change
    JOHANNES contact HAUSHOFER; Fiscal Year: 2010
  8. SALIVARY AMYLASE--ROLE IN DENTAL CARIES PATHOGENESIS
    Narayanan Ramasubbu; Fiscal Year: 2002
  9. GASTROINTESTINAL PHYSIOLOGY OF CHOLECYSTOKININ
    Joseph Reeve; Fiscal Year: 1993
  10. Risk for Dysfunctional Romantic Relationships for Adults
    DEBORAH CAPALDI; Fiscal Year: 2009

Detail Information

Publications205 found, 100 shown here

  1. ncbi Alcohol-induced protein kinase Calpha phosphorylation of Munc18c in carbachol-stimulated acini causes basolateral exocytosis
    Laura I Cosen-Binker
    Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Gastroenterology 132:1527-45. 2007
    ..This alcohol-induced susceptibility mechanism of pancreatitis is unknown...
  2. ncbi Low serum amylase levels in drinking alcoholics
    Katsuya Maruyama
    Department of Internal Medicine, National Alcoholism Center, Kurihama Hospital, Yokosuka, Kanagawa, Japan
    Alcohol Clin Exp Res 27:16S-21S. 2003
    ..To elucidate the mechanism of this phenomenon, pancreatic isoamylase, salivary isoamylase, and amylase in urine were measured together with total serum amylase...
  3. ncbi The islet-acinar axis of the pancreas: more than just insulin
    Savio G Barreto
    Department of General and Digestive Surgery, Flinders Medical Centre and Flinders University, Adelaide, South Australia, Australia 5042
    Am J Physiol Gastrointest Liver Physiol 299:G10-22. 2010
    ....
  4. ncbi Biochemical analysis of serum pancreatic amylase and lipase enzymes in patients with type 1 and type 2 diabetes mellitus
    Adib A Aughsteen
    Faculty of Pharmacy, Al Zaytoonah University, PO Box 130, Amman 11733, Jordan
    Saudi Med J 26:73-7. 2005
    ..To examine the pancreatic exocrine insufficiency in patient with diabetes mellitus by estimating serum pancreatic amylase and lipase enzymes in healthy subjects and in type 1 and type 2 diabetic patients...
  5. ncbi Secretin-stimulated amylase release into blood is impaired in type 1 diabetes mellitus
    A Swislocki
    Section of Endocrinology, Medical Service, Veterans Affairs Medical Center, Martinez, California 94553, USA
    Horm Metab Res 37:326-30. 2005
    ....
  6. ncbi Mice lacking the transcription factor Mist1 exhibit an altered stress response and increased sensitivity to caerulein-induced pancreatitis
    Agnes S Kowalik
    Department of Physiology, The University of Western Ontario, London, Ontario, Canada
    Am J Physiol Gastrointest Liver Physiol 292:G1123-32. 2007
    ....
  7. ncbi Bacterial diversity and bioprospecting for cold-active lipases, amylases and proteases, from culturable bacteria of kongsfjorden and Ny-alesund, Svalbard, Arctic
    T N R Srinivas
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad, 500 007, India
    Curr Microbiol 59:537-47. 2009
    ..Fatty acid profile studies indicated that short chain fatty acids, unsaturated fatty acids, branched fatty acids, the cyclic and the cis fatty acids are predominant in the psychrophilic bacteria...
  8. ncbi Use of mesophilic fungal amylases produced by solid-state fermentation in the cold hydrolysis of raw babassu cake starch
    Aline Machado de Castro
    Research and Development Center, Renewable Energy Division, PETROBRAS, Av Horácio Macedo, 950 Ilha do Fundão, Rio de Janeiro, Brazil
    Appl Biochem Biotechnol 162:1612-25. 2010
    b>Amylases constitute one of the most important groups of industrial enzymes, presenting several applications, such as in the food, textile, and ethanol manufacturing...
  9. ncbi Attenuated cerulein-induced pancreatitis in nuclear factor-kappaB-deficient mice
    Domenica Altavilla
    Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Italy
    Lab Invest 83:1723-32. 2003
    ..Our data suggest that KO mice have an attenuated cerulein-induced pancreatitis and help to define the possible interaction between NF-kappaB activation and oxidative stress in this deleterious event...
  10. ncbi Compartmentalization of proteinases and amylases in Nauphoeta cinerea midgut
    E N Elpidina
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, Moscow, Russia
    Arch Insect Biochem Physiol 48:206-16. 2001
    Compartmentalization of proteinases, amylases, and pH in the midgut of Nauphoeta cinerea Oliv. (Blattoptera:Blaberidae) was studied in order to understand the organization of protein and starch digestion...
  11. ncbi Infliximab: a new therapeutic agent in acute pancreatitis?
    Nevin Oruc
    Ege University, Faculty of Medicine, Gastroenterology Department, Izmir, Turkey
    Pancreas 28:e1-8. 2004
    ..The aim of this study is to investigate the therapeutic effectiveness of monoclonal TNF antibody (infliximab) in acute edematous and severe necrotizing pancreatitis models in rats...
  12. ncbi Understanding salivary fluid and protein secretion
    R James Turner
    Membrane Biology Section, Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda 20892-1190, USA
    Oral Dis 8:3-11. 2002
  13. ncbi Amylase-resistant starch as adjunct to oral rehydration therapy in children with diarrhea
    P Raghupathy
    Department of Child Health, Christian Medical College, Vellore, India
    J Pediatr Gastroenterol Nutr 42:362-8. 2006
    ..CONCLUSION: In children with acute diarrhea, the addition of amylase-resistant starch to glucose ORS significantly shortened duration of diarrhea compared with standard treatment...
  14. ncbi Effects of a beverage containing an enzymatically induced-viscosity dietary fiber, with or without fructose, on the postprandial glycemic response to a high glycemic index food in humans
    B W Wolf
    Ross Products Division, Abbott Laboratories, Columbus, OH 43215 1724, USA
    Eur J Clin Nutr 57:1120-7. 2003
    ....
  15. ncbi Lipid peroxidation inhibition reduces NF-kappaB activation and attenuates cerulein-induced pancreatitis
    Domenica Altavilla
    Section of Pharmacology, Department of Clinical and Experimental Medicine and Pharmacology, University of Messina (Azienda Ospedaliera Universitario G. Martino, Tore Biologica 5th Floor, Via Consolare Valeria, Gazzi, 98100 Messina, Italy
    Free Radic Res 37:425-35. 2003
    ..Indeed, lipid peroxidation inhibition might be considered a potential therapeutic approach to prevent the severe damage in acute pancreatitis...
  16. ncbi Purification of alpha-amylases using magnetic alginate beads
    S Teotia
    Chemistry Department, Indian Institute of Technology, Delhi, Hauz Khas
    Appl Biochem Biotechnol 90:211-20. 2001
    Magnetic alginate beads were used to purify alpha-amylases from porcine pancreas, starchzyme, BAN 240L (a commercial purification from Bacillus subtilis), and wheat germ...
  17. ncbi Inhibition of inducible nitric oxide synthase reduces bacterial translocation in a rat model of acute pancreatitis
    I Simsek
    Department of Internal Medicine, Gulhane School of Medicine, Ankara, Turkey
    Pancreas 23:296-301. 2001
    ..S-methylisothiourea (SMT) is an inducible nitric oxide synthase inhibitor that has been shown to decrease bacteria] translocation in sepsis and thermal injury...
  18. ncbi Laboratory diagnostic tests in acute pancreatitis
    Joseph Smotkin
    Division of Gastroenterology, Department of Medicine, Maimonides Medical Center, Brooklyn, New York 11219, USA
    J Clin Gastroenterol 34:459-62. 2002
    ..This review summarizes important aspects of standard laboratory tests and novel laboratory approaches in establishing the diagnosis, etiology, and severity of acute pancreatitis...
  19. ncbi Rapid urinary trypsinogen-2 test strip in the diagnosis of acute pancreatitis
    Yen-Ting Chen
    Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
    Pancreas 30:243-7. 2005
    ..A positive test identifies patients in need of further diagnostic measures. The urinary trypsinogen-2 test can be performed in health care units where laboratory testing facilities are not immediately available...
  20. ncbi Histopathologic correlates of serum amylase activity in acute experimental pancreatitis
    J Schmidt
    Department of Surgery, Massachusetts General Hospital, Boston 02114
    Dig Dis Sci 37:1426-33. 1992
    ..31). Inasmuch as edema and fat necrosis are not important determinants of severity, these observations could explain the poor prognostic value of serum amylase activity in patients with acute pancreatitis...
  21. ncbi Heterologous protein secretion by Lactobacillus plantarum using homologous signal peptides
    G Mathiesen
    Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, As, Norway
    J Appl Microbiol 105:215-26. 2008
    ..plantarum, and to compare the functionality of these signal peptides with that of well-known heterologous signal peptides (Usp45, M6)...
  22. ncbi Cholecystokinin antagonist L364,718 induces alterations in acinar cells that prevent improvement of acute pancreatitis induced by obstruction
    Isabel de Dios
    Department of Physiology and Pharmacology and University of Salamanca, Spain
    Dig Dis Sci 47:1800-9. 2002
    ..The CCK receptor antagonist L364,718 produces alterations in the acinar calcium homeostasis that prevent to reduction in the severity of pancreatitis induced by obstruction...
  23. ncbi Cholecystokinin blockade triggers earlier and enhanced intra-acinar oxygen free radical generation in acute pancreatitis induced by pancreatic duct obstruction in rats
    Aranzazu Urunuela
    Department of Physiology and Pharmacology, University of Salamanca, 37007 Salamanca, Spain
    Clin Sci (Lond) 105:203-12. 2003
    ..The detrimental effect of L364,718 in AP induced by PDO suggests that plasma CCK does not play a major role in the development of this AP model...
  24. ncbi Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level
    Weiyan Yao
    Department of Gastroenterology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
    J Gastroenterol Hepatol 22:1866-71. 2007
    ..The aim of this study was to investigate the effect of thymosin alpha 1 (TA1) on severe acute pancreatitis (SAP) in rats...
  25. ncbi Effects of octreotide pretreatment in experimental acute pancreatitis
    Marcelo Z Salem
    Department of Gastroenterology, Surgical Division, , , Brazil
    Pancreatology 3:164-8. 2003
    ..CONCLUSION: Octreotide administration acutely increases the enzymatic content of the pancreas and thus may have a potential deleterious influence in the evolution of AP...
  26. ncbi Influence of ischemic preconditioning on blood coagulation, fibrinolytic activity and pancreatic repair in the course of caerulein-induced acute pancreatitis in rats
    Z Warzecha
    Department of Physiology, Jagiellonian University Medical College, Krakow, Poland
    J Physiol Pharmacol 58:303-19. 2007
    ..The aim of the investigation was to determine whether ischemic preconditioning affects the course edematous pancreatitis...
  27. ncbi The role of adenosine A2a receptors in experimental acute pancreatitis
    K Celinski
    Department of Gastroenterology, Medical University, Lublin ul Solarza 16, 20 815 Lublin, Poland
    Adv Med Sci 51:105-10. 2006
    ..The aim was to evaluate the effects of the adenosine A2a receptor agonist and antagonist in the severe, taurocholate-induced experimental acute pancreatitis (EAP)...
  28. ncbi Systemic lupus erythematosus-related acute pancreatitis: a case report
    Hueng-Chuen Fan
    Department of Pediatrics, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC
    J Microbiol Immunol Infect 36:212-4. 2003
    ..9 mg/dL; C4, 2.3 mg/dL) during the pancreatitis attack suggested that the pancreatitis may have been due to systemic lupus erythematosus exacerbation and not related to drug therapy...
  29. ncbi Management of gallstone pancreatitis
    Shawn D Larson
    Department of Surgery, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0536, USA
    Adv Surg 40:265-84. 2006
    ..The management of these patients requires close clinical observation and a multidisciplinary approach between the surgeon, radiologist, gastroenterologist, and intensivist...
  30. ncbi Effects of bee venom on cholecystokinin octapeptide-induced acute pancreatitis in rats
    Sang Wan Seo
    Department of Herbology, College of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570 749, South Korea
    Pancreas 36:e22-9. 2008
    ..Bee venom (BV) has frequently been used as a remedy for inflammatory diseases. The aim of this study was to investigate the effect of BV on cholecystokinin octapeptide (CCK-8)-induced acute pancreatitis (AP) in rats...
  31. ncbi Effects of early decompression and cholecystokinin inhibition in rats with acute pancreatitis induced by bile-pancreatic-duct obstruction
    Isabel de Dios
    Department of Physiology and Pharmacology, University of Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain
    J Lab Clin Med 141:265-71. 2003
    ..CCK blockade does not accelerate pancreatic recovery after BPDO opening...
  32. ncbi The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis
    Adem Karatas
    Department of General Surgery, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey
    J Surg Res 148:7-12. 2008
    ..The aim of this paper is to assess the effects of halofuginone, a specific inhibitor of synthesis of collagen Type 1, on fibrogenetic process in an experimental model of early pancreatic fibrosis...
  33. ncbi Pancreatic microcirculatory impairment in experimental acute pancreatitis in rats
    Zong guang Zhou
    III Department of General Surgery Gastroenteric Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China
    World J Gastroenterol 8:933-6. 2002
    ..To study the feature of pancreatic microcirculatory impairment, especially the initial changes, in caerulein-induced experimental acute pancreatitis (AP)...
  34. ncbi Stimulation of sensory nerves and CGRP attenuate pancreatic damage in ischemia/reperfusion induced pancreatitis
    Artur Dembinski
    Department of Physiology, Jagiellonian University Medical School, Cracow, Poland
    Med Sci Monit 9:BR418-25. 2003
    ..The aim of this study was to examine the role of capsaicin-sensitive nerves and the impact of CGRP administration on necrotizing pancreatitis induced by ischemia/reperfusion...
  35. ncbi Effects of moderate hypothermia on proinflammatory cytokine production in a rat model of caerulein-induced pancreatitis
    Koji Matsuoka
    Department of Surgery II, Yamaguchi University School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505, Japan
    Pancreas 26:e12-7. 2003
    ..CONCLUSION: Our results suggest that MH may be clinically applicable for reducing the severity of AP...
  36. ncbi Influence of leptin administration on the course of acute ischemic pancreatitis
    Z Warzecha
    Department of Physiology, Jagiellonian University Medical School, Cracow, Poland
    J Physiol Pharmacol 53:775-90. 2002
    ..The beneficial effects of leptin appear to be dependent on the improvement of pancreatic blood flow, the increase in pancreatic cell growth, and the limitation of pro-inflammatory interleukin-1beta release...
  37. ncbi Role of endogenous melatonin and its MT2 receptor in the modulation of caerulein-induced pancreatitis in the rat
    J Jaworek
    Chair of Physiology, Jagiellonian University School of Medicine, , Poland
    J Physiol Pharmacol 53:791-804. 2002
    ..These results suggest that endogenous melatonin through its receptor MT2 plays an important role in the attenuation of pancreatic damage produced by overstimulation with caerulein...
  38. ncbi Is there correlation between pancreatic enzyme and radiological severity in acute pancreatitis?
    Yeon Soo Kim
    Department of Internal Medicine, Daejeon St Mary s Hospital Medical College of the Catholic University of Korea, Korea
    World J Gastroenterol 14:2401-5. 2008
    ..To investigate the correlation between the changes of pancreatic enzyme, the biochemical markers and the clinical results according to the Balthazar computer tomography (CT) grade...
  39. ncbi Oxygen radicals promote ICAM-1 expression and microcirculatory disturbances in experimental acute pancreatitis
    Tobias Keck
    Department of Surgery, University of Freiburg, Germany
    Pancreatology 3:156-63. 2003
    ....
  40. ncbi [Acute experimental pancreatitis in the opossum. The role of early splenectomy in the inflammatory response]]
    H A Garcia
    Secciòn Cirugìa Experimental, Servicio de Cirugìa General Hospital Churruca Visca
    Acta Gastroenterol Latinoam 32:71-7. 2002
    ..Acute pancreatitis (AP) does not escape this disconcert. In fact, like in every severe acute inflammatory process, its discontrol could be responsible of the high morbidity and mortality rates...
  41. ncbi Inhibition of tyrosine-kinase-mediated cellular signaling by tyrphostins AG 126 and AG556 modulates murine experimental acute pancreatitis
    Srinivasan Balachandra
    Hepatobiliary Unit, Department of Surgery, Manchester Royal Infirmary, England
    Surgery 138:913-23. 2005
    ....
  42. ncbi p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I
    Sophie Vasseur
    Centre de Recherche INSERM, EMI 0116, 163 Avenue de Luminy, BP172, 13009 Marseille, France
    J Biol Chem 279:7199-207. 2004
    ..In conclusion, p8 improves pancreatic resistance to inducers of acute pancreatitis by a mechanism implicating the expression of the anti-inflammatory protein PAP I...
  43. ncbi Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen
    Lena Selig
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Leipzig, Leipzig, Germany
    BMC Gastroenterol 6:30. 2006
    ..The R122H mutation of the cationic trypsinogen was found in patients with hereditary pancreatitis. A transgenic animal carrying this mutation could be useful as a genetic model system of pancreatitis...
  44. ncbi Inhibitory effect of Patrinia scabiosaefolia on acute pancreatitis
    Sang Wan Seo
    Department of Herbology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570 749, South Korea
    World J Gastroenterol 12:1110-4. 2006
    ..To investigate the effect of Patrinia scabiosaefolia (PS) on the cholecystokinin (CCK) octapeptide-induced acute pancreatitis (AP) in rats...
  45. ncbi Beneficial effect of resveratrol on cholecystokinin-induced experimental pancreatitis
    Annamaria Szabolcs
    First Department of Medicine, University of Szeged, Faculty of Medicine, H 6720 Szeged, Koranyi fasor 8, Hungary
    Eur J Pharmacol 532:187-93. 2006
    ..In conclusion, the beneficial effects of resveratrol on acute pancreatitis seem to be mediated by the antioxidant effect of resveratrol or by an NF-kappaB-independent anti-inflammatory mechanism...
  46. ncbi Factors contributing to infectious diarrhea-associated pancreatic enzyme alterations
    Jean Marie Reimund
    Service d Hépato Gastroentérologie et d Assistance Nutritive, Hopitaux Universitaires de Strasbourg, Hopital de Hautepierre, Avenue Moliere, 67098 Strasbourg Cedex
    Gastroenterol Clin Biol 29:247-53. 2005
    ..We studied 59 patients presenting acute infectious diarrhea in order to determine the incidence as well as to identify factors which may contribute to the occurrence of pancreatic enzyme alteration or true acute pancreatitis...
  47. ncbi Should serum pancreatic lipase replace serum amylase as a biomarker of acute pancreatitis?
    Ross C Smith
    Sydney University Department of Surgery, Royal North Shore Hospital, Sydney New South Wales, Australia
    ANZ J Surg 75:399-404. 2005
    ..Serum pancreatic lipase may improve the diagnosis of pancreatitis compared to serum amylase. Both enzymes have been measured simultaneously at our hospital allowing for a comparison of their diagnostic accuracy...
  48. ncbi Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas
    Francisco C Muñoz-Casares
    Department of General Surgery, Reina Sofia University Hospital, Cordoba, Spain
    J Pineal Res 40:195-203. 2006
    ..Preventive or therapeutic administration of melatonin protected against the induction of oxidative stress and tissue injury, and restored cell function in experimental pancreatic IR in rats...
  49. ncbi Dose-response for inhibition by amylin of cholecystokinin-stimulated secretion of amylase and lipase in rats
    Andrew A Young
    Amylin Pharmaceuticals Inc, 9360 Towne Centre Drive, San Diego, CA 92121, USA
    Regul Pept 130:19-26. 2005
    ..The neuroendocrine hormone amylin, cosecreted with insulin from pancreatic beta-cells in response to nutrient ingestion, has several physiologic actions to limit the rate of nutrient uptake, including the slowing of gastric emptying...
  50. ncbi Effects of R-102444 and its active metabolite R-96544, selective 5-HT2A receptor antagonists, on experimental acute and chronic pancreatitis: Additional evidence for possible involvement of 5-HT2A receptors in the development of experimental pancreatitis
    Taketoshi Ogawa
    Pharmacology and Molecular Biology Research Laboratories, Sankyo Co, Ltd, 1 2 58 Hiromachi, Tokyo 140 8710, Japan
    Eur J Pharmacol 521:156-63. 2005
    ..These results clearly indicate that R-102444 and R-96544 inhibit the progression of acute and chronic pancreatitis and support the contention of possible involvement of 5-HT2A receptors in the progression of experimental pancreatitis...
  51. ncbi Different effects of dexamethasone and the nitric oxide synthase inhibitor L-NAME on caerulein-induced rat acute pancreatitis, depending on the severity
    Yusuke Sugiyama
    Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii cho, Kamigyo, Kyoto, 802 8566, Japan
    Inflammopharmacology 13:291-301. 2005
    ..It is assumed that endogenous NO may be involved in oedema formation as the early event in the development of acute pancreatitis...
  52. ncbi Reduction of ischemia/reperfusion injury by antithrombin III after experimental pancreas transplantation
    Thilo Hackert
    Department of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
    Am J Surg 189:92-7. 2005
    ..Antithrombin III (AT III) is an anticoagulatory and anti-inflammatory substance. The aim of our study was to evaluate a prophylactic application of AT III in experimental pancreas transplantation...
  53. ncbi Differences in platelet endothelial cell adhesion molecule-1 expression between peripheral circulation and pancreatic microcirculation in cerulein-induced acute edematous pancreatitis
    Hong Kai Gao
    Department of General Surgery, Division of Digestive Surgery and Organ Microcirculation, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    World J Gastroenterol 11:661-4. 2005
    ....
  54. ncbi Early bacterial infection of the pancreas and course of disease in cerulein-induced acute pancreatitis in rats
    G Manes
    Department of Gastroenterology, Otto von Guericke University Magdeburg, Germany
    Dig Liver Dis 38:423-8. 2006
    ..Since bacterial translocation from the gut is likely to be an early event, in an animal model of pancreatitis, we investigated the effect of early bacterial supra-infection of the pancreas on the course of the disease...
  55. ncbi Does the septic shock interfere experimental acute pancreatitis in rats?
    S Hac
    Department of General Endocrine and Transplant Surgery, Medical University of Gdansk, 7 Debinki Street, 80 952 Gdansk, Poland
    Med Chem 2:423-9. 2006
    ..Two complex and multifactorial pathogenetic ways lead to edematous or necrotizing pancreatitis. The course of the disease is thought to be the consequence of an acute inflammatory response...
  56. ncbi Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis
    Letteria Minutoli
    Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina AOU G. Martino Torre Biologica 5th floor, Via Consolare Valeria, Gazzi 98100, Messina, Italy
    Life Sci 75:2853-66. 2004
    ....
  57. ncbi Inosine alleviates rat caerulein pancreatitis and pancreatitis-associated lung injury
    Tetsuya Yamagiwa
    Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan
    J Gastroenterol 39:41-9. 2004
    ..CONCLUSIONS: Inosine reduced the severity of acute pancreatitis, suggesting a possible application of this compound in the treatment of acute pancreatitis...
  58. ncbi Quantification of pancreatic zinc output as pancreatic function test: making the secretin-caerulein test applicable to clinical practice
    J Enrique Domínguez-Muñoz
    Department of Gastroenterology, University Hospital, Santiago de Compostela, Spain
    Pancreatology 4:57-62. 2004
    ..The aim of this study was to analyze the accuracy of the secretin-caerulein-stimulated pancreatic zinc output as pancreatic function test in comparison with the standard SCT...
  59. ncbi Melatonin precursor; L-tryptophan protects the pancreas from development of acute pancreatitis through the central site of action
    A Leja-Szpak
    Department Med. Physiology Faculty of Health Care, Jagiellonian University Medical College, Cracow, Poland
    J Physiol Pharmacol 55:239-54. 2004
    ..The beneficial effect of centrally administered L-tryptophan could be mediated through activation of central receptors for locally produced melatonin...
  60. ncbi Pancreatic and bile duct obstruction exacerbates rat caerulein-induced pancreatitis: a new experimental model of acute hemorrhagic pancreatitis
    Mitsuo Yamasaki
    Department of Surgery, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-sayama 595-8511, Japan
    J Gastroenterol 41:352-60. 2006
    ..CONCLUSIONS: Preceding biliopancreatic duct obstruction exacerbates caerulein-induced pancreatitis. Enhancement of intracellular trypsin activation is possibly involved in this mechanism...
  61. ncbi The circadian rhythm of melatonin modulates the severity of caerulein-induced pancreatitis in the rat
    Jolanta Jaworek
    Department of Medical Physiology, Faculty of Health Care, Medical Faculty, Jagiellonian University CM, 31 531 Krakow, Poland
    J Pineal Res 37:161-70. 2004
    ....
  62. ncbi Platelet function in acute experimental pancreatitis
    Thilo Hackert
    Department of Surgery, University of Heidelberg, INF 110, 69120, Heidelberg, Germany
    J Gastrointest Surg 11:439-44. 2007
    ..Mainly temporary platelet-endothelium interaction is observed during mild AP, whereas severe AP is characterized by firm adhesion with consecutive coagulatory activation and perfusion failure...
  63. ncbi Aqueous extract of black tea (Camellia sinensis) prevents ethanol+cholecystokinin-induced pancreatitis in a rat model
    Dolan Das
    Department of Physiology, Presidency College, Calcutta, India
    Life Sci 78:2194-203. 2006
    ..These findings suggest that BTE prevents pancreatitis caused by chronic EtOH+CCK toxicity presumably by enhancing antioxidant, anti-inflammatory and antiapoptotic activity in rats...
  64. ncbi Early microcirculatory derangement in mild and severe pancreatitis models in mice
    H M Chen
    First Department of Surgery, Tohoku University School of Medicine, Sendai, Japan
    Surg Today 31:634-42. 2001
    ..These results suggest that during the early course of acute pancreatitis, leukocyte adherence in the pancreatic microcirculation is a secondary event following the increase in pancreatic vascular permeability...
  65. ncbi Blockade of bradykinin B(2) receptor suppresses acute pancreatitis induced by obstruction of the pancreaticobiliary duct in rats
    Mitsuhiro Hirata
    Department of Surgery, Kitasato University School of Medicine, Kitasato, Sagamihara, Kanagawa 228-8555, Japan
    Br J Pharmacol 135:29-36. 2002
    ..6. These findings suggest a possible involvement of kinin B(2) receptor in the present pancreatitis model. Furthermore, they point to the potential usefulness of the B(2) receptor in clinical acute pancreatitis...
  66. ncbi [Pseudo acute pancreatitis: a syndrome mimicked by a multiple parasitic duodenitis. Analysis of 7 case]
    O M Tiscornia
    , , Universidad de Buenos Aires
    Acta Gastroenterol Latinoam 31:319-22. 2001
    ....
  67. ncbi [The isolated perfused rat pancreas - an experimental model for investigation the early events in the pathogenesis of acute pancreatitis]
    R Mantke
    , Germany
    Zentralbl Chir 126:929-33. 2001
    ..05) after 50 minutes perfusion.CONCLUSIONS: The isolated perfused rat pancreas is a valuable experimental model to investigate the early phase of pathophysiology in acute pancreatitis...
  68. ncbi The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats
    Zoltan Rakonczay
    First Department of Medicine, University of Szeged, Szeged, Hungary
    Pancreas 24:83-9. 2002
    ..HSPs are proteins that help cells to survive stress conditions by repairing damaged proteins...
  69. ncbi Hepatocyte growth factor attenuates pancreatic damage in caerulein-induced pancreatitis in rats
    Z Warzecha
    Department of Physiology, Jagiellonian University Medical School, , 31-531, Cracow, Poland
    Eur J Pharmacol 430:113-21. 2001
    ....
  70. ncbi Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis
    Adam S Paszkowski
    Departments of General Surgery and Pathology, University of Ulm, Ulm, Germany
    Ann Surg 235:68-76. 2002
    ..Moreover, ICE inhibition is still effective after a therapeutic window of 12 hours. Based on the current findings, future studies on the clinical application of ICE-inhibiting substances in acute pancreatitis seem to be promising...
  71. ncbi Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
    W Halangk
    Department of Surgery, Division of Experimental Surgery, Otto von Guericke Universitat, Magdeburg, Germany
    J Clin Invest 106:773-81. 2000
    ..These experiments provide the first conclusive evidence to our knowledge that cathepsin B plays a role in intrapancreatic trypsinogen activation and the onset of acute pancreatitis...
  72. ncbi Involvement of cyclooxygenase-derived prostaglandin E2 and nitric oxide in the protection of rat pancreas afforded by low dose of lipopolysaccharide
    J Jaworek
    University School of Medicine, Jagiellonian University, , Poland
    J Physiol Pharmacol 52:107-26. 2001
    ..the NO-system is involved in above stimulation of PGE2 generation and pancreatic protection against acute damage...
  73. ncbi Effect of sensory nerves and CGRP on the development of caerulein-induced pancreatitis and pancreatic recovery
    Z Warzecha
    Department of Physiology, Jagiellonian University School of Medicine, Cracow, Poland
    J Physiol Pharmacol 52:679-704. 2001
    ..After induction of AP, persistent activity of sensory nerves and presence of CGRP aggravate pancreatic damage and lead to functional insufficiency typical for chronic pancreatitis...
  74. ncbi Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice
    Salvatore Cuzzocrea
    Institute of Pharmacology, School of Medicine, University of Messina, Italy
    Cytokine 18:274-85. 2002
    ....
  75. ncbi Induction of heat shock proteins fails to produce protection against trypsin-induced acute pancreatitis in rats
    Z Rakonczay
    First Department of Medicine, University of Szeged, Hungary
    Clin Exp Med 2:89-97. 2002
    ..The findings suggest that the induction of HSP60 or HSP72 are not enough to protect rats against the early phase of this localized necrohemorrhagic pancreatitis model...
  76. ncbi Deleterious effect of Helicobacter pylori infection on the course of acute pancreatitis in rats
    Zygmunt Warzecha
    Department of Physiology, Jagiellonian University Medical School, , Poland
    Pancreatology 2:386-95. 2002
    ....
  77. ncbi The influence of epidermal growth factor on the course of ischemia-reperfusion induced pancreatitis in rats
    R Tomaszewska
    1 Department of Clinical and Experimental Pathomorphology, Jagiellonian University School of Medicine, , Poland
    J Physiol Pharmacol 53:183-98. 2002
    ....
  78. ncbi Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats
    Zoltan Rakonczay
    First Department of Medicine, University of Szeged, Hungary
    Free Radic Biol Med 32:1283-92. 2002
    ..Nontoxic heat shock protein (HSP) inducer compounds open up promising therapeutic possibilities by activating one of the natural and highly conserved defense mechanisms of the organism...
  79. ncbi Comparative effects of water immersion pretreatment on three different acute pancreatitis models in rats
    Tamas Takacs
    First Department of Medicine, University of Szeged, Hungary
    Biochem Cell Biol 80:241-51. 2002
    ..Unexpectedly, CWI pretreatment was detrimental to the morphological parameters of TC-induced pancreatitis. It was demonstrated that CWI and HWI pretreatment only influenced cytokine synthesis in Arg-induced pancreatitis...
  80. ncbi Macroamylasemia attributable to gluten-related amylase autoantibodies: a case report
    G Barera
    Department of Pediatrics, Scientific Institute H San Raffaele, University of Milan, Milan, Italy
    Pediatrics 107:E93. 2001
    ..We report a girl with CD, autoimmune thyroiditis, and MA, in whom CD-related antibodies to amylase and to exocrine pancreas tissue resolved with a gluten-free diet...
  81. ncbi Effect of NF-kappaB and p38 MAPK in activated monocytes/macrophages on pro-inflammatory cytokines of rats with acute pancreatitis
    Hong Shan Liu
    Department of Hepatobiliary Surgery, First Affiliated Hospital, Xi an Jiaotong University, Xi an 710061, Shaanxi Province, China
    World J Gastroenterol 9:2513-8. 2003
    ..The aim of the study was to investigate the effect of NF-kappaB and p38 MAPK in activated monocytes/macrophages on cytokines of rats with acute pancreastitis...
  82. ncbi Mobilization of xanthine oxidase from the gastrointestinal tract in acute pancreatitis
    Susana Granell
    Dept, of Experimental Pathology, Institut d Investigacions Biomèdiques de Barcelona Consejo Superior de Investigaciones Científicas IIBB CSIC, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    BMC Gastroenterol 4:1. 2004
    ....
  83. ncbi Stimulatory effect of PG-KII, an NK3 tachykinin receptor agonist, on isolated pancreatic acini: species-related differences
    G Linari
    Department of Human Physiology and Pharmacology V Erspamer, University of Rome La Sapienza, P le A Moro 5, 00185 Rome, Italy
    Peptides 25:45-51. 2004
    ..The NK3 receptor system cooperates with the other known secretagogues in regulating guinea pig exocrine pancreatic secretion and undergoes rapid homologous desensitization...
  84. ncbi Comparison of alpha-amylase activity in larval stages of flour beetles, Tribolium confusum (Coleoptera: Tenebionidae)
    A R Bandani
    Plant Protection Department, Faculty of Agricultre, University of Tehran, Karaj, Iran
    Commun Agric Appl Biol Sci 71:537-41. 2006
    ....
  85. ncbi Interaction of salivary alpha-amylase and amylase-binding-protein A (AbpA) of Streptococcus gordonii with glucosyltransferase of S. gordonii and Streptococcus mutans
    Biswendu Chaudhuri
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, New York, USA
    BMC Microbiol 7:60. 2007
    ..We examined the interaction of amylase and recombinant AbpA (rAbpA), together with Gtfs of S. gordonii and S. mutans...
  86. ncbi Icodextrin degradation products in spent dialysate of CAPD patients and the rat, and its relation with dialysate osmolality
    D R de Waart
    Department of Clinical Chemistry, University of Amsterdam, The Netherlands
    Perit Dial Int 21:269-74. 2001
    ..The aim of this study was to quantitate breakdown products of icodextrin (which could explain this peak) and investigate whether there was a relationship with dialysate amylase concentration and dialysate osmolality...
  87. ncbi Plant alpha-amylase inhibitors and their interaction with insect alpha-amylases
    Octavio L Franco
    Centro Nacional de Recursos Genéticos e Biotecnologia, Cenargen Embrapa, Brasilia DF, Brazil
    Eur J Biochem 269:397-412. 2002
    ..The enzyme inhibitors impede digestion through their action on insect gut digestive alpha-amylases and proteinases, which play a key role in the digestion of plant starch and proteins...
  88. ncbi Parasympathetic non-adrenergic, non-cholinergic transmission in rat parotid glands: effects of cholecystokinin-A and -B receptor antagonists on the secretory response
    J Ekstrom
    Section of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Goteborg University, Medicinaregatan 15 D, 413 90, Goteborg, Sweden
    Regul Pept 146:278-84. 2008
    ..Thus, under physiological conditions, the cholecystokinin receptors of the parotid gland are likely to be stimulated by circulating hormones rather than by nervous activity...
  89. ncbi Icodextrin metabolism and alpha-amylase activity in nonuremic rats undergoing chronic peritoneal dialysis
    Elvia Garcia Lopez
    Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden
    Perit Dial Int 27:415-23. 2007
    ..To study the metabolism of icodextrin and alpha-amylase activity following daily exposure to dialysis solutions containing either glucose or icodextrin as osmotic agent in rats...
  90. ncbi Phlebotomus papatasi and Leishmania major parasites express alpha-amylase and alpha-glucosidase
    R L Jacobson
    Department of Parasitology, The Kuvin Center for the Study of Infectious and Tropical Diseases, The Hebrew University Hadassah Medical School, 91120, Jerusalem, Israel
    Acta Trop 78:41-9. 2001
    ..In this study, we demonstrate that P. papatasi and L. major possess the enzymes for hydrolyzing starch grains that are included in the plant tissue-diet of the sand flies...
  91. ncbi Extracellular alpha-amylase from Thermus filiformis Ork A2: purification and biochemical characterization
    M C Egas
    Departamento de Bioquimica, Universidade de Coimbra, Portugal
    Extremophiles 2:23-32. 1998
    ..To our knowledge this is the first report of the characterization of an alpha-amylase from a strain of the genus Thermus...
  92. ncbi Oral colonization and cariogenicity of Streptococcus gordonii in specific pathogen-free TAN:SPFOM(OM)BR rats consuming starch or sucrose diets
    J M Tanzer
    Department of Oral Diagnosis, School of Dental Medicine, University of Connecticut Health Center, Farmington, CT 06030 1605, USA
    Arch Oral Biol 46:323-33. 2001
    ..Caries scores are augmented by sucrose compared with starch, and are further augmented by S gordonii colonization. S. gordonii is thus cariologically significant in the presence of sucrose, at least in this rat...
  93. ncbi Different polyphenolic components of soft fruits inhibit alpha-amylase and alpha-glucosidase
    Gordon J McDougall
    Quality, Health and Nutrition Programme, Genes to Products Theme, Scottish Crop Research Institute, Invergowrie, Dundee, DD2 5DA, UK
    J Agric Food Chem 53:2760-6. 2005
    ..The inhibitory components were identified as ellagitannins using LC-MS-MS. This study suggests that different polyphenolic components of fruits may influence different steps in starch digestion in a synergistic manner...
  94. ncbi New approach for separating Bacillus subtilis metalloprotease and alpha-amylase by affinity chromatography and for purifying neutral protease by hydrophobic chromatography
    I Lauer
    Centre de Recherche TEPRAL, Branche Boissons du Groupe Danone, Strasbourg, France
    J Chromatogr B Biomed Sci Appl 737:277-84. 2000
    ..The homogeneity of the purified protease was confirmed by SDS-PAGE, which showed that its MW was about 38. pH and temperature optima were also determined on the fraction...
  95. ncbi Hyperamylasemia and acute pancreatitis following anticholinesterase poisoning
    Surjit Singh
    Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Hum Exp Toxicol 26:467-71. 2007
    ..Mild elevation of serum amylase is common in patients with anticholinesterase poisoning. However, acute pancreatitis is rare...
  96. ncbi Possible involvement of β₁ receptors in various emetogen-induced increases in salivary amylase activity in rats
    Hideo Fukui
    Development Research Center, Takeda Pharmaceutical Company, Ltd, Osaka, Japan
    J Pharmacol Sci 115:69-74. 2011
    ....
  97. ncbi Starch with a slow digestion property produced by altering its chain length, branch density, and crystalline structure
    Zihua Ao
    Whistler Center for Carbohydrate Research and Department of Food Science, Purdue University, West Lafayette, Indiana 47907 2009, USA
    J Agric Food Chem 55:4540-7. 2007
    ..Both the increase of the starch branch density and the crystalline structure in the treated starches likely contribute to their slow digestion property...
  98. ncbi Probing the role of aromatic residues at the secondary saccharide-binding sites of human salivary alpha-amylase in substrate hydrolysis and bacterial binding
    Chandran Ragunath
    Department of Oral Biology, University of Medicine and Dentistry of New Jersey, C 634, MSB, 185 South Orange Avenue, Newark, NJ 07103, USA
    J Mol Biol 384:1232-48. 2008
    ..These results clearly show that the aromatic residues at the secondary saccharide-binding sites in HSAmy play a critical role in bacterial binding and in starch-hydrolytic functions of HSAmy...
  99. ncbi Job categories and their effect on exposure to fungal alpha-amylase and inhalable dust in the U.K. baking industry
    Joanne Elms
    Health and Safety Laboratory, Broad Lane, Sheffield, S3 7HQ, UK
    AIHA J (Fairfax, Va) 64:467-71. 2003
    ....
  100. ncbi Arg-27, Arg-127 and Arg-155 in the beta-trefoil protein barley alpha-amylase/subtilisin inhibitor are interface residues in the complex with barley alpha-amylase 2
    K W Rodenburg
    Carlsberg Laboratory, Department of Chemistry, Copenhagen, Denmark
    Biochem J 309:969-76. 1995
    ..j. 293, 151-155]...
  101. ncbi [Validity of serum amylase and lipase in the differential diagnosis between acute/acutized chronic pancreatitis and other causes of acute abdominal pain]
    Ricardo Custódio Pacheco
    Departamento de Clinica Medica, Faculdade de Medicina, Universidade Federal de UberlândiaSão Paulo, SP
    Arq Gastroenterol 40:233-8. 2003
    ..Raised serum amylase and lipase levels are observed in several abdominal diseases...

Research Grants72

  1. Self-Regulation as a Biological Mechanism for Excess Weight Gain in Toddlers
    Alison L Miller; Fiscal Year: 2010
    ..The results could therefore be broadly applicable to more effective prevention of other unhealthy behaviors such as substance abuse. ..
  2. GENETIC COMPETENCE IN STREPTOCCUS MUTANS BIOFILMS
    Dennis Cvitkovitch; Fiscal Year: 2001
    ..The program should elucidate the environmental conditions, physiology, and genetics fostering gene transfer among S. mutans cells growing in biofilms. ..
  3. The Course of Regulation and Dysregulation in Children
    TRACY LORRAINE SPINRAD; Fiscal Year: 2010
    ..g., stress, parenting). ..
  4. The Course of Regulation and Dysregulation in Children
    Nancy Eisenberg; Fiscal Year: 2009
    ..g., stress, parenting). ..
  5. IN VIVO STUDIES OF SALIVA ANTIMICROBIAL PROTEINS
    JOEL RUDNEY; Fiscal Year: 2001
    ..By focusing on redundancy and complexing, this project also addresses the question of whether individual proteins exert unique and specific effects in the mouth. ..
  6. NOVEL PROTEASE FORMULATION BASED ON CROSSLINKED CRYSTALS
    Bhami Shenoy; Fiscal Year: 2004
    ..TheraCLEC-Protease will be ready to enter clinical trials, and will provide a novel treatment for pancreatic insufficiency in chronic pancreatitis and cystic fibrosis along with TheraCLECLipase. ..
  7. Poverty, Stress, and Discounting: A potential micro-mechanism for behavior change
    JOHANNES contact HAUSHOFER; Fiscal Year: 2010
    ....
  8. SALIVARY AMYLASE--ROLE IN DENTAL CARIES PATHOGENESIS
    Narayanan Ramasubbu; Fiscal Year: 2002
    ..Such mutants will permit the design of strategies to manipulate human salivary amylase-bacterial interactions that favor the host and thus reduce the potential for caries. ..
  9. GASTROINTESTINAL PHYSIOLOGY OF CHOLECYSTOKININ
    Joseph Reeve; Fiscal Year: 1993
    ..The major goal of these studies is to determine the physiological significance of CCK-58...
  10. Risk for Dysfunctional Romantic Relationships for Adults
    DEBORAH CAPALDI; Fiscal Year: 2009
    ....
  11. Risk for Dysfunctional Romantic Relationships for Adults
    Deborah M Capaldi; Fiscal Year: 2010
    ....