chickenpox vaccine

Summary

Summary: A live, attenuated varicella virus vaccine used for immunization against chickenpox. It is recommended for children between the ages of 12 months and 13 years.

Top Publications

  1. ncbi Parental attitudes toward varicella vaccination. The Puget Sound Pediatric Research Network
    J A Taylor
    Department of Pediatrics, University of Washington School of Medicine, Seattle 98103 8652, USA
    Arch Pediatr Adolesc Med 154:302-6. 2000
  2. ncbi A decline in varicella but an uncertain impact on zoster following varicella vaccination in Victoria, Australia
    Kylie S Carville
    Epidemiology Unit, Victorian Infectious Diseases Reference Laboratory, Australia
    Vaccine 28:2532-8. 2010
  3. pmc Epidemiology of varicella zoster virus infection in Canada and the United Kingdom
    M Brisson
    PHLS CDSC, and City University, London
    Epidemiol Infect 127:305-14. 2001
  4. ncbi Exposure to varicella boosts immunity to herpes-zoster: implications for mass vaccination against chickenpox
    M Brisson
    Immunisation Division, PHLS Communicable Disease Surveillance Centre, London, UK
    Vaccine 20:2500-7. 2002
  5. ncbi Herpes zoster in Australia: evidence of increase in incidence in adults attributable to varicella immunization?
    A Jardine
    Public Health Unit, Sydney South West Area Health Service, Camperdown, New South Wales
    Epidemiol Infect 139:658-65. 2011
  6. ncbi The incidence of varicella and herpes zoster in Taiwan during a period of increasing varicella vaccine coverage, 2000-2008
    D Y Chao
    Graduate Institute of Microbiology and Public Health, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan
    Epidemiol Infect 140:1131-40. 2012
  7. ncbi Population-based incidence of herpes zoster after introduction of a publicly funded varicella vaccination program
    Peter Tanuseputro
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Vaccine 29:8580-4. 2011
  8. ncbi Aging, immunity, and the varicella-zoster virus
    Ann Arvin
    Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 352:2266-7. 2005
  9. ncbi Herpes zoster keratouveitis and inflammatory ocular hypertension 8 years after varicella vaccination
    Phoebe Lin
    Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA
    Ocul Immunol Inflamm 17:33-5. 2009
  10. ncbi Current immunization policies for pneumococcal, meningococcal C, varicella and rotavirus vaccinations in Italy
    Valeria Alfonsi
    Istituto Superiore di Sanità ISS, National Center for Epidemiology Surveillance and Health Promotion CNESPS, Rome, Italy
    Health Policy 103:176-83. 2011

Research Grants

Detail Information

Publications243 found, 100 shown here

  1. ncbi Parental attitudes toward varicella vaccination. The Puget Sound Pediatric Research Network
    J A Taylor
    Department of Pediatrics, University of Washington School of Medicine, Seattle 98103 8652, USA
    Arch Pediatr Adolesc Med 154:302-6. 2000
    ..To evaluate parental health beliefs regarding the varicella vaccine and to identify potential areas for interventions designed to increase immunization against varicella...
  2. ncbi A decline in varicella but an uncertain impact on zoster following varicella vaccination in Victoria, Australia
    Kylie S Carville
    Epidemiology Unit, Victorian Infectious Diseases Reference Laboratory, Australia
    Vaccine 28:2532-8. 2010
    ..Among those aged 80 and over the hospitalisation rate increased 5% per year (95% CI 3-7%) from 1998 to 2007. Zoster increased in community data from 2001...
  3. pmc Epidemiology of varicella zoster virus infection in Canada and the United Kingdom
    M Brisson
    PHLS CDSC, and City University, London
    Epidemiol Infect 127:305-14. 2001
    ..Finally, our results provide baseline estimates of varicella and zoster incidence and morbidity for VZV vaccine effectiveness and cost-effectiveness studies...
  4. ncbi Exposure to varicella boosts immunity to herpes-zoster: implications for mass vaccination against chickenpox
    M Brisson
    Immunisation Division, PHLS Communicable Disease Surveillance Centre, London, UK
    Vaccine 20:2500-7. 2002
    ..Mass varicella vaccination is expected to cause a major epidemic of herpes-zoster, affecting more than 50% of those aged 10-44 years at the introduction of vaccination...
  5. ncbi Herpes zoster in Australia: evidence of increase in incidence in adults attributable to varicella immunization?
    A Jardine
    Public Health Unit, Sydney South West Area Health Service, Camperdown, New South Wales
    Epidemiol Infect 139:658-65. 2011
    ....
  6. ncbi The incidence of varicella and herpes zoster in Taiwan during a period of increasing varicella vaccine coverage, 2000-2008
    D Y Chao
    Graduate Institute of Microbiology and Public Health, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan
    Epidemiol Infect 140:1131-40. 2012
    ..Continuous monitoring is needed to understand the secular trends in HZ before and after varicella vaccination in Taiwan and in other countries...
  7. ncbi Population-based incidence of herpes zoster after introduction of a publicly funded varicella vaccination program
    Peter Tanuseputro
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Vaccine 29:8580-4. 2011
    ..We assessed the impact of childhood varicella vaccination in Ontario, Canada on zoster incidence and healthcare visits, and established baseline zoster rates prior to zoster vaccine introduction...
  8. ncbi Aging, immunity, and the varicella-zoster virus
    Ann Arvin
    Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 352:2266-7. 2005
  9. ncbi Herpes zoster keratouveitis and inflammatory ocular hypertension 8 years after varicella vaccination
    Phoebe Lin
    Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA
    Ocul Immunol Inflamm 17:33-5. 2009
    ..Herpes zoster ophthalmicus is very rare in the pediatric population after varicella vaccination but can cause severe inflammatory glaucoma that requires aggressive therapy...
  10. ncbi Current immunization policies for pneumococcal, meningococcal C, varicella and rotavirus vaccinations in Italy
    Valeria Alfonsi
    Istituto Superiore di Sanità ISS, National Center for Epidemiology Surveillance and Health Promotion CNESPS, Rome, Italy
    Health Policy 103:176-83. 2011
    ....
  11. ncbi Cost-effectiveness of varicella vaccination programs: an update of the literature
    Mark H Rozenbaum
    Groningen Research Institute of Pharmacy GRIP, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    Expert Rev Vaccines 7:753-82. 2008
    ..Despite that, those aspects limit the timeliness of our review and we believe that the current work does provide useful insights in the cost-effectiveness of varicella vaccination...
  12. pmc Varicella zoster disease of the central nervous system: epidemiological, clinical, and laboratory features 10 years after the introduction of the varicella vaccine
    Barbara A Pahud
    Division of Pediatric Infectious Diseases, University of California, San Francisco, USA
    J Infect Dis 203:316-23. 2011
    ....
  13. ncbi Safety and immunogenicity of early vaccination with two doses of tetravalent measles-mumps-rubella-varicella (MMRV) vaccine in healthy children from 9 months of age
    P Goh
    SingHealth Polyclinics Tampines, 1, Tampines Street 41, Singapore, 529203, Singapore
    Infection 35:326-33. 2007
    ....
  14. ncbi Assessment of varicella vaccine effectiveness in Germany: a time-series approach
    M Hohle
    Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
    Epidemiol Infect 139:1710-9. 2011
    ....
  15. ncbi Herpes zoster virus sclerokeratitis and anterior uveitis in a child following varicella vaccination
    Ayman Naseri
    Francis I Proctor Foundation and Department of Ophthalmology, University of California at San Francisco Medical Center, San Francisco, California, USA
    Am J Ophthalmol 135:415-7. 2003
    ..To report a case of herpes zoster virus sclerokeratitis with anterior uveitis following vaccination with live attenuated varicella vaccine (Oka strain)...
  16. ncbi Reactogenicity and immunogenicity of a live attenuated tetravalent measles-mumps-rubella-varicella (MMRV) vaccine
    Terry Nolan
    The University of Melbourne, Department of Paediatrics, and Murdoch Children s Research Institute at the Royal Children s Hospital, Melbourne, Australia
    Vaccine 21:281-9. 2002
    ..This tetravalent MMRV candidate vaccine showed promising results, although further examination of the possible increase in minor fever and decreased varicella immunogenicity should be assessed in future studies...
  17. ncbi Transmission of varicella vaccine virus to a non-family member in China
    Lin Gan
    Department of Microbiology, Anhui Medical University, Hefei, 230032, China
    Vaccine 29:2015-7. 2011
    ..This is the first report in China in which an adult with varicella was attributable to vaccine virus and the 6th report of transmission of vaccine virus to a susceptible adult around the world...
  18. ncbi Herpes zoster and meningitis due to reactivation of varicella vaccine virus in an immunocompetent child
    Jin Young Han
    Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA
    Pediatr Infect Dis J 30:266-8. 2011
    ..Vaccine strain of VZV was recovered from a skin swab and the cerebrospinal fluid. Reactivation of the vaccine strain of VZV should be recognized as a potential cause of meningitis in children...
  19. ncbi One dose of varicella vaccine does not prevent school outbreaks: is it time for a second dose?
    Adriana S Lopez
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pediatrics 117:e1070-7. 2006
    ....
  20. ncbi Scientific commentary
    Aisha Jumaan
    Vaccine 22:3228-31; author reply 3232-6. 2004
  21. ncbi Immunogenicity and safety of a measles-mumps-rubella-varicella vaccine following a 4-week or a 12-month interval between two doses
    H C Rumke
    Vaxinostics BV, University Vaccine Center Rotterdam Nijmegen, Rotterdam, The Netherlands
    Vaccine 29:3842-9. 2011
    ....
  22. pmc Decline in varicella-related ambulatory visits and hospitalizations in the United States since routine immunization against varicella
    Samir S Shah
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Pediatr Infect Dis J 29:199-204. 2010
    ..Widespread varicella vaccination has led to substantial decreases in varicella-related mortality and hospitalizations. The effect of the vaccine on ambulatory care utilization is poorly defined...
  23. ncbi Safety of varicella vaccine after licensure in the United States: experience from reports to the vaccine adverse event reporting system, 1995-2005
    Sandra S Chaves
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 197:S170-7. 2008
    ..Ongoing safety surveillance and further studies may shed light on some of the hypothesized associations...
  24. ncbi Uveitis associated with varicella virus vaccine
    B Esmaeli-Gutstein
    Ophthalmology Section, M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Am J Ophthalmol 127:733-4. 1999
    ..To report a case of uveitis associated with the live attenuated varicella virus vaccine (Varivax; Merck & Co, Inc, West Point, Pennsylvania) in a young, otherwise healthy girl...
  25. pmc The incidence of varicella and herpes zoster in Massachusetts as measured by the Behavioral Risk Factor Surveillance System (BRFSS) during a period of increasing varicella vaccine coverage, 1998-2003
    W Katherine Yih
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, USA
    BMC Public Health 5:68. 2005
    ..While varicella incidence would be expected to decrease, mathematical models predict an initial increase in herpes zoster incidence if re-exposure to varicella protects against reactivation of the varicella zoster virus...
  26. ncbi Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine
    Myron J Levin
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80045 0508, USA
    J Infect Dis 198:1444-7. 2008
    ..The presence of distinct strains in skin lesions and cerebrospinal fluid indicate that >1 variant strain may reactivate to cause herpes zoster...
  27. ncbi The postmarketing safety profile of varicella vaccine
    R G Sharrar
    Worldwide Product Safety and Epidemiology, Merck Research Laboratories, BLB 30, PO Box 4, West Point, PA 19486, USA
    Vaccine 19:916-23. 2000
    ..Eleven patients were hospitalized with complications of breakthrough varicella infection...
  28. ncbi Impact of universal vaccination on the epidemiology of varicella in Veneto, Italy
    Francesca Pozza
    Direction of Prevention, Veneto Region, Venice, Italy
    Vaccine 29:9480-7. 2011
    ..There was a remarkable decline of both varicella incidence and hospitalizations especially in 1-4 year-old children. This study confirms the positive impact of universal vaccination...
  29. ncbi Varicella in infants after implementation of the US varicella vaccination program
    Sandra S Chaves
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pediatrics 128:1071-7. 2011
    ..To describe varicella disease in infants since implementation of the varicella vaccination program in the United States...
  30. pmc Epidemiological characteristics of varicella from 2000 to 2008 and the impact of nationwide immunization in Taiwan
    Luan Yin Chang
    Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    BMC Infect Dis 11:352. 2011
    ..Varicella has an important impact on public health. Starting in 2004 in Taiwan, nationwide free varicella vaccinations were given to 1-year-old children...
  31. ncbi Chickenpox in childhood is associated with decreased atopic disorders, IgE, allergic sensitization, and leukocyte subsets
    Jonathan I Silverberg
    Department of Dermatology, St Luke s Roosevelt Hospital and Beth Israel Medical Centers, New York, NY 10025, USA
    Pediatr Allergy Immunol 23:50-8. 2012
    ..We sought to determine whether WTVZV in childhood protects against atopic disorders, allergic sensitization or decreases serum Immunoglobulin E (IgE) levels...
  32. ncbi Near elimination of varicella deaths in the US after implementation of the vaccination program
    Mona Marin
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pediatrics 128:214-20. 2011
    ..Since then, vaccination coverage has increased substantially. We updated the analysis of US varicella mortality for 2002-2007 and assessed the impact of the first 12 years of the US varicella vaccination program on varicella deaths...
  33. ncbi Economic evaluations of varicella vaccination programmes: a review of the literature
    Nancy Thiry
    Department of Epidemiology and Social Medicine, Centre for the Evaluation of Vaccination, University of Antwerp, Antwerp, Belgium
    Pharmacoeconomics 21:13-38. 2003
    ..Since violation of these assumptions could have important adverse public health effects, we suggest pre-adolescent vaccination as a more secure alternative. This option deserves more attention in future analyses...
  34. ncbi Safety profile of live varicella virus vaccine (Oka/Merck): five-year results of the European Varicella Zoster Virus Identification Program (EU VZVIP)
    Nicolas Goulleret
    Sanofi Pasteur MSD, Lyon, France
    Vaccine 28:5878-82. 2010
    ..The European VZVIP provides data on VZV clade distribution...
  35. ncbi The effectiveness of the varicella vaccine in clinical practice
    M Vazquez
    Department of Pediatrics, Yale University School of Medicine, New Haven, Conn 06520 8064, USA
    N Engl J Med 344:955-60. 2001
    ..A live attenuated varicella vaccine was approved for use in the United States in March 1995 and is recommended for all susceptible persons 12 months of age or older...
  36. pmc Varicella vaccination in England and Wales: cost-utility analysis
    M Brisson
    Immunisation Division, PHLS Communicable Disease Surveillance Centre, London NW9 5EQ, UK
    Arch Dis Child 88:862-9. 2003
    ..To assess the cost-effectiveness of varicella vaccination, taking into account its impact on zoster...
  37. ncbi The epidemiology of varicella and herpes zoster in The Netherlands: implications for varicella zoster virus vaccination
    Hester de Melker
    Centre for Infectious Disease Epidemiology, National Institute of Public Health and the Environment, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Vaccine 24:3946-52. 2006
    ..Insight into epidemiology of varicella zoster is needed for the assessment of the desirability of introduction of routine varicella zoster vaccination...
  38. ncbi Incidence of herpes zoster among children and adolescents in a community with moderate varicella vaccination coverage
    G S Goldman
    P O Box 847, Pearblossom, CA 93553, USA
    Vaccine 21:4243-9. 2003
    ..Unvaccinated children with a previous history of varicella may have greater sensitivity to exogenous exposures (boosting) and a poorer cell-mediated response following primary infection relative to older age groups...
  39. ncbi Aplastic anemia following varicella vaccine
    Paola Angelini
    Division of Haematology and Oncology, Hospital for Sick Children, Toronto, Canada
    Pediatr Infect Dis J 28:746-8. 2009
    ..A causative association between the vaccine and the hematologic disease is possible, and pediatricians should be aware of this severe although rare adverse event...
  40. ncbi Knowledge, attitudes, and practices regarding varicella vaccination among health care providers participating in the varicella active surveillance project, Antelope Valley, California, 2005
    Tina Carbajal
    Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA
    J Infect Dis 197:S66-70. 2008
    ....
  41. ncbi Secondary transmission of varicella vaccine virus in a chronic care facility for children
    Richard Grossberg
    Hattie Larlham Center for Children With Disabilities, Mantua, Ohio, USA
    J Pediatr 148:842-4. 2006
    ..We demonstrate that vaccine-strain virus was transmitted to both persons, and that transmission included at least 2 variant vaccine strains...
  42. ncbi Varicella
    Ulrich Heininger
    Division of Paediatric Infectious Diseases and Vaccinology, University Children s Hospital, Basel, Switzerland
    Lancet 368:1365-76. 2006
    ..Similar immunisation programmes have been adopted by some other countries, including Uruguay, Germany, Taiwan, Canada, and Australia, and are expected to be implemented more widely in future...
  43. ncbi The case against universal varicella vaccination
    Gary S Goldman
    Medical Veritas International Inc, Pearblossom, California 93553, USA
    Int J Toxicol 25:313-7. 2006
    ..Deleterious outcomes and their associated costs must be included when making a circumspect assessment of the Universal Varicella Vaccination Program...
  44. ncbi Varicella outbreak epidemiology in an active surveillance site, 1995-2005
    Rachel Civen
    Los Angeles County Department of Public Health, Los Angeles, California 90012, USA
    J Infect Dis 197:S114-9. 2008
    ....
  45. ncbi Changing dynamics of varicella-zoster virus infections in the 21st century: the impact of vaccination
    Richard J Whitley
    J Infect Dis 191:1999-2001. 2005
  46. ncbi Varicella vaccines
    Andrew Flatt
    University College London Hospitals NHS Foundation Trust, London, UK
    Br Med Bull 103:115-27. 2012
    ..The use of live-attenuated varicella vaccine to reduce the burden of these diseases has been established in many countries for a number of years...
  47. ncbi Metaanalysis of vaccine effectiveness in varicella outbreaks
    Otmar Bayer
    Institute for Social Paediatrics and Adolescent Medicine, Ludwig Maximilians University, Heiglhofstr 63, 81377 Munich, Germany
    Vaccine 25:6655-60. 2007
    ..Waning might also be an issue with the newly recommended two dose vaccination schedule. Sustained surveillance for varicella outbreaks in populations with varicella immunization programs therefore is mandatory...
  48. ncbi Chickenpox and pneumonia following varicella vaccine
    Ghan Shyam Lohiya
    Infect Control Hosp Epidemiol 25:530. 2004
  49. ncbi Recurrent papular urticaria after varicella immunization in a fifteen-month-old girl
    David E Bronstein
    Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Pediatr Infect Dis J 24:269-70. 2005
    ..We describe a 15-month-old girl who experienced the onset of recurring papular urticaria after varicella immunization. The rash was varicella-like and thought by us to be caused by vaccine virus...
  50. ncbi Breakthrough VZV infection after immunization, presenting as herpes zoster
    Rogier P Schade
    Department of Medical Microbiology, Nijmegen, The Netherlands
    Scand J Infect Dis 40:428-30. 2008
    ..Interestingly, the infection manifested as herpes zoster of 1 dermatome. Typing showed wild-type virus, which suggests that exogenous reinfection with a new strain may present as herpes zoster...
  51. ncbi Challenges to implementing second-dose varicella vaccination during an outbreak in the absence of a routine 2-dose vaccination requirement--Maine, 2006
    Amy A Parker
    Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention CDC, Atlanta, Georgia, USA
    J Infect Dis 197:S101-7. 2008
    ..These findings support ACIP's June 2007 recommendation for a routine 2-dose varicella vaccination program...
  52. pmc Identification of potential candidates for varicella vaccination by history: questionnaire and seroprevalence study
    Eithne MacMahon
    Department of Infection, Guy s and St Thomas Hospital NHS Trust, London SE1 7EH
    BMJ 329:551-2. 2004
  53. ncbi A combined measles, mumps, rubella and varicella vaccine (Priorix-Tetra): immunogenicity and safety profile
    Hanna Czajka
    Vaccination Outpatient Clinic, Szpital sw Ludwika, ul Strzelecka 2, 31 503 Cracow, Poland
    Vaccine 27:6504-11. 2009
    ....
  54. ncbi Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP)
    Mona Marin
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, CDC, Atlanta, GA 30333, USA
    MMWR Recomm Rep 59:1-12. 2010
    ..cdc.gov/vaccines/recs/provisional/downloads/combo-vax-Aug2009-508.pdf), which state that use of a combination vaccine generally is preferred over its equivalent component vaccines...
  55. ncbi Varicella infection following varicella vaccination in a liver transplant recipient
    Josh Levitsky
    Center for Liver Diseases Section of Gastroenterology, University of Chicago Hospitals, IL, USA
    Am J Transplant 2:880-2. 2002
    ..We will discuss VZV infection, particularly in relation to liver transplantation, and review the prophylaxis and management of VZV infection after OLT...
  56. ncbi Modeling the impact of one- and two-dose varicella vaccination on the epidemiology of varicella and zoster
    Marc Brisson
    Departement de Medecine sociale et preventive, Universite Laval, Quebec, Canada
    Vaccine 28:3385-97. 2010
    ..Adding a 2-dose program may help guarantee high population-level effectiveness against varicella. However, the incremental benefit of a second dose is highly dependant on the effectiveness of the first dose and its impact on zoster...
  57. ncbi [Incidence of herpes zoster in pediatricians and history of reexposure to varicella-zoster virus in patients with herpes zoster]
    K Terada
    Department of Pediatrics, Kawasaki Medical School
    Kansenshogaku Zasshi 69:908-12. 1995
    ..Therefore, we can speculate that the varicella vaccine may protect against herpes zoster in the elderly by the enhanced specific cellular immunity due to the booster effect...
  58. ncbi Varicella vaccine and shingles
    Marc Brisson
    JAMA 287:2211; author reply 2211-2. 2002
  59. ncbi Complications of varicella after implementation of routine childhood varicella vaccination in Germany
    Michaela Spackova
    European Programme for Intervention Epidemiology Training, European Centre for Disease Prevention and Control, Stockholm, Sweden
    Pediatr Infect Dis J 29:884-6. 2010
    ..Case-based questionnaires are completed for VC. We evaluated trend and clinical features of reported VC from April 2005 to March 2009. Reported VC decreased by 81%...
  60. pmc Varicella vaccination during early pregnancy: a cause of in utero miliary fetal tissue calcifications and hydrops?
    Joseph Apuzzio
    Department of Obstetrics, Gynecology and Women s Health, New Jersey Medical School, Newark, New Jersey 07103 2714, USA
    Infect Dis Obstet Gynecol 10:159-60. 2002
    ....
  61. ncbi Varicella breakthrough infection and vaccine effectiveness in Taiwan
    Wen Chan Huang
    Department of Pediatrics, National Taiwan University, Taipei, Taiwan
    Vaccine 29:2756-60. 2011
    ..001). The vaccine effectiveness against varicella was 82.6% and against varicella-related hospitalization was 85.4% from 2000 to 2005...
  62. ncbi Varicella immunization practices and the factors that influence them
    S J Schaffer
    Strong Children s Research Center, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY, USA
    Arch Pediatr Adolesc Med 153:357-62. 1999
    ..To evaluate the varicella immunization practices of physicians in Rochester, NY, and to identify factors that predict whether physicians administer varicella vaccine to children...
  63. ncbi The effect of funded varicella immunization programs on varicella-related hospitalizations in IMPACT centers, Canada, 2000-2008
    Ben Tan
    Department of Pediatrics, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Pediatr Infect Dis J 31:956-63. 2012
    ..Publicly funded routine immunization programs at 12 or 15 months of age were introduced by 5 provinces and territories (prov/terr) in 2000 to 2002 (earlier programs, EP) and by 8 prov/terr in 2004 to 2007 (later programs, LP)...
  64. ncbi Varicella vaccine--are two doses better than one?
    Anne A Gershon
    N Engl J Med 347:1962-3. 2002
  65. ncbi The safety and immunogenicity of a quadrivalent measles, mumps, rubella and varicella vaccine in healthy children: a study of manufacturing consistency and persistence of antibody
    Jay M Lieberman
    Miller Children s Hospital, UCLA Center for Vaccine Research, Long Beach, CA 90806, USA
    Pediatr Infect Dis J 25:615-22. 2006
    ..An additional objective was to evaluate the persistence of antibodies 1 year postvaccination...
  66. pmc Attitudes and practices regarding varicella vaccination among physicians in Minnesota: implications for public health and provider education
    K R Ehresmann
    Acute Disease Epidemiology Section, Minnesota Department of Health, Minneapolis 55414, USA
    Am J Public Health 90:1917-20. 2000
    ..This study sought to determine physicians' attitudes and practices regarding varicella vaccine...
  67. ncbi The burden of varicella complications before the introduction of routine varicella vaccination in Germany
    Johannes G Liese
    Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munich, Germany
    Pediatr Infect Dis J 27:119-24. 2008
    ..The true burden of varicella complications in Germany is not known. We investigated the incidence and pattern of varicella complications in children and adolescents using 3 independent surveillance sources...
  68. ncbi Complications of varicella requiring hospitalisation before and after the introduction of varicella vaccine in a children's hospital in Taiwan
    Yu Yu Chuang
    Division of Paediatric Infectious Diseases, Chang Gung Children s Hospital, 5 Fu Shin Street, Kweishan, Taoyuan, Taiwan
    Eur J Pediatr 162:112-3. 2003
  69. ncbi Growth, morbidity and mortality after chickenpox infection in young children in Guinea-Bissau
    Anja Poulsen
    Projecto de Saude de Bandim, Guinea Bissau, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    J Infect 51:307-13. 2005
    ..To examine whether chickenpox in children below 2 years of age is associated with post-infection changes in growth, morbidity or mortality...
  70. ncbi Instituting a routine varicella vaccination program in Canada: an economic evaluation
    Denis Getsios
    Caro Research, Montreal, Canada
    Pediatr Infect Dis J 21:542-7. 2002
    ..The evaluation of a program of vaccination of 12-month-old children, with and without a catch-up program for susceptible 12-year-olds, is presented here...
  71. pmc Varicella: epidemiological aspects and vaccination coverage in the Veneto Region
    Vincenzo Baldo
    Department of Environmental Medicine and Public Health, Institute of Hygiene, University of Padua, Padua, Italy
    BMC Infect Dis 9:150. 2009
    ..To evaluate parameters at the start of the programme, we conducted a study to describe the epidemiology of varicella infection and coverage rates for varicella vaccine in the Veneto Region (North-East Italy)...
  72. ncbi The effect of vaccination on the epidemiology of varicella zoster virus
    W J Edmunds
    Immunisation Division, Colindale, London NW9 5EQ, UK
    J Infect 44:211-9. 2002
    ..Meanwhile sensitive surveillance of both chickenpox and shingles is essential in countries that have implemented, or are about to implement, varicella vaccination...
  73. ncbi Economic evaluation of varicella vaccination in Italian children and adolescents according to different intervention strategies: the burden of uncomplicated hospitalised cases
    Paolo Bonanni
    Department of Public Health, University of Florence, Viale Morgagni 48, 50134 Florence, Italy
    Vaccine 26:5619-26. 2008
    ..Overall, our analysis confirmed the favourable clinical and economic impact of routine varicella vaccination with two doses of vaccine in Italy...
  74. ncbi Varicella vaccines and measles, mumps, rubella, and varicella vaccine
    Lucia Ferro Bricks
    Departamento de Pediatria, Faculdade de Medicina da Universidade de São Paulo USP, Sao Paulo, SP, Brazil
    J Pediatr (Rio J) 82:S101-8. 2006
    ..To present an up-to-date review of studies investigating the efficacy, adverse events and vaccination regimens of the varicella vaccine and the new presentation combined with the vaccine for measles, mumps and rubella...
  75. ncbi Prevention strategies: experience of varicella vaccination programmes
    David Patrick
    University of British Columbia, Centre for Disease Control, Vancouver, BC, Canada
    Herpes 14:48-51. 2007
    ..Ongoing surveillance for the reactivation of herpes zoster and safety programmes are also highlighted as key recommendations...
  76. pmc Complete DNA sequences of two oka strain varicella-zoster virus genomes
    Sueli L Tillieux
    Viral Vaccines Research and Development, GlaxoSmithKline Biologicals, Rue de l Institut, 89 P31 005, B 1330 Rixensart, Belgium
    J Virol 82:11023-44. 2008
    ....
  77. ncbi Analysis of the persistence of humoral and cellular immunity in children and adults immunized with varicella vaccine
    L Zerboni
    Department of Pediatrics, Stanford University School of Medicine, California 94305 5208, USA
    J Infect Dis 177:1701-4. 1998
    ..In summary, varicella immunization induced long-term humoral and cellular immunity, and initial differences between cell-mediated responses in children and adults diminished over time...
  78. ncbi Identification of CD8+ T cell epitopes in the immediate early 62 protein (IE62) of varicella-zoster virus, and evaluation of frequency of CD8+ T cell response to IE62, by use of IE62 peptides after varicella vaccination
    Christian R Frey
    Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA, and Faculty of Biosciences, University of Witten Herdecke, Witten, Germany
    J Infect Dis 188:40-52. 2003
    ..Varicella vaccination of 3 VZV-immune subjects was associated with increases in IE62 peptide-specific CD8(+) T cells, a finding indicating that in vivo re-exposure boosts memory immunity to this important viral protein...
  79. ncbi An outbreak of varicella in elementary school children with two-dose varicella vaccine recipients--Arkansas, 2006
    Philip L Gould
    Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 28:678-81. 2009
    ..In October 2006, the Arkansas Department of Health was notified of a varicella outbreak among students where some received a second dose during an outbreak-related vaccination campaign in February 2006...
  80. ncbi An elementary school outbreak of varicella attributed to vaccine failure: policy implications
    Brian R Lee
    Immunization, Tuberculosis, and International Health Section, Infectious Disease Epidemiology, Prevention, and Control Division, Minnesota Department of Health, Minneapolis 55414, USA
    J Infect Dis 190:477-83. 2004
    ....
  81. ncbi Varicella outbreaks after vaccine licensure: should they make you chicken?
    U Buchholz
    Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pediatrics 104:561-3. 1999
    ..Vaccine effectiveness was within the range predicted by the literature. Vaccination led to a lower attack rate in the highly vaccinated CCC and appeared to protect from severe disease...
  82. ncbi Hospitalizations for varicella in the United States, 1988 to 1999
    Karin Galil
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 21:931-5. 2002
    ..Varicella epidemiology is changing with increasing use of the varicella vaccine...
  83. pmc Comparison of the complete DNA sequences of the Oka varicella vaccine and its parental virus
    Yasuyuki Gomi
    Kanonji Institute, The Research Foundation for Microbial Diseases of Osaka University, Kanonji, Kagawa, Japan
    J Virol 76:11447-59. 2002
    ..Furthermore, the Oka vaccine virus was completely distinguishable from P-Oka and 54 clinical isolates by seven restriction-enzyme fragment length polymorphisms that detected differences in the DNA sequence...
  84. ncbi Use of National Health Insurance database to evaluate the impact of public varicella vaccination program on burden of varicella in Taiwan
    Hung Fu Tseng
    Institute of Medical Research, Chang Jung Christian University, 396, Sec l, Chang Jung Rd, Kway Jen, Tainan 711, Taiwan, ROC
    Vaccine 24:5341-8. 2006
    ..The reductions also occurred in every age group including infants and adults. This study showed significant evidence of vaccine impact with a marked decline in clinical cases in the short term...
  85. ncbi Varicella vaccination in Australia
    K K Macartney
    National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases NCIRS, The Children s Hospital at Westmead, New South Wales, Australia
    J Paediatr Child Health 41:544-52. 2005
    ..The potential impact of varicella vaccination on the incidence of herpes zoster is also discussed...
  86. ncbi The changing epidemiology of varicella incidence after implementation of the one-dose varicella vaccination policy
    Ie Bin Lian
    Graduate Institute of Statistics and Information Science, National Changhua University of Education, Changhua 50058, Taiwan
    Vaccine 29:1448-54. 2011
    ..The current study provides important implications for the current vaccination policy...
  87. pmc Varicella vaccination in Europe - taking the practical approach
    Paolo Bonanni
    Department of Public Health, University of Florence, Florence, Italy
    BMC Med 7:26. 2009
    ....
  88. ncbi Disease burden and epidemiological characteristics of varicella in Taiwan from 2000 to 2005
    Yung Hsiu Lin
    Division of Infectious Diseases, Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan
    J Microbiol Immunol Infect 42:5-12. 2009
    ..This study investigated the epidemiological characteristics and disease burden of varicella during the introduction of the varicella vaccine for mass vaccination in Taiwan...
  89. ncbi Postlicensure safety surveillance for varicella vaccine
    R P Wise
    Division of Epidemiology, Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, FDA CBER HFM 225, Rockville, MD 20852 1448, USA
    JAMA 284:1271-9. 2000
    ....
  90. ncbi Molecular analysis of the Oka vaccine strain of varicella-zoster virus
    Koichi Yamanishi
    National Institute of Biomedical Innovation, Ibaraki, Osaka, Japan
    J Infect Dis 197:S45-8. 2008
    ....
  91. ncbi Varicella vaccination of children in the United States: assessment after the first decade 1995-2005
    Charles Grose
    Virology Laboratory, Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    J Clin Virol 33:89-95; discussion 96-8. 2005
    ..In addition, data from varicella vaccination programs in Europe should provide further insight into the effectiveness of varicella vaccination in different geographic and ethnic populations...
  92. ncbi Safety and immunogenicity of a combination measles, mumps, rubella and varicella vaccine (ProQuad)
    Barbara J Kuter
    Merck Research Laboratories, P 0 Box 4, West Point 19426, Pennsylvania, USA
    Hum Vaccin 2:205-14. 2006
    ..Inc, West Point, PA) was evaluated in five clinical trials. Use of ProQuad would result in fewer injections for children and would facilitate universal immunization against all four diseases...
  93. ncbi Hospitalization rates for complicated and uncomplicated chickenpox in a poorly vaccined pediatric population
    F Bonsignori
    Department of Paediatrics, University of Florence, Anna Meyer Children s Hospital, Via Luca Giordano, 13, I 50132, Florence, Italy
    Infection 35:444-50. 2007
    ..A retrospective study was conducted to provide epidemiological data on hospitalization for complicated and uncomplicated chickenpox in a pediatric population...
  94. ncbi Immunogenicity and safety of a second dose of measles-mumps-rubella-varicella vaccine in healthy children aged 5 to 6 years
    Timo Vesikari
    University of Tampere Medical School, Tampere, Finland
    Pediatr Infect Dis J 26:153-8. 2007
    ..Given the overlap in MMR and varicella vaccination schedules, development of a combined vaccine appears logical and would facilitate the introduction of 2 doses of varicella vaccination in healthy children with no additional injections...
  95. ncbi Physician attitudes regarding breakthrough varicella disease and a potential second dose of varicella vaccine
    Matthew M Davis
    Child Health Evaluation and Research Unit, Division of General Pediatrics, University of Michigan, Ann Arbor, MI, USA
    Pediatrics 119:258-64. 2007
    ..We assessed physicians' attitudes about the 1-dose varicella vaccination program and whether physicians think a 2-dose recommendation is needed to reduce the risk of breakthrough disease...
  96. ncbi [Impact of universal varicella vaccination in Germany: an epidemiological and economic analysis]
    M Knuf
    Kinderklinik und Kinderpoliklinik, Johannes Gutenberg Universitat, Langenbeckstrasse 1, 55101 Mainz
    Klin Padiatr 218:203-12. 2006
    ..From these findings it can be concluded that universal varicella vaccination is a strategy which should be encouraged, from a medical, epidemiological, but also economic viewpoint...
  97. ncbi Varicella vaccination in Europe: are we ready for a universal childhood programme?
    Nitu Sengupta
    Centre for Child Health, Royal London Hospital, 38 New Road, Whitechapel, London, E1 2AX, UK
    Eur J Pediatr 167:47-55. 2008
    ..The SIEVE recommends the implementation of such a policy as soon as financially and practically possible...
  98. ncbi Epidemiology of varicella in Connecticut, 2001-2005
    Lynn E Sosa
    Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 197:S90-3. 2008
    ..Continued surveillance is needed in order to monitor changing trends in varicella epidemiology...
  99. ncbi An economic analysis of the universal varicella vaccination program in the United States
    Fangjun Zhou
    National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia, USA
    J Infect Dis 197:S156-64. 2008
    ....
  100. ncbi Varicella disease among vaccinated persons: clinical and epidemiological characteristics, 1997-2005
    Sandra S Chaves
    Centers for Disease Control and Prevention, Atlanta, Georgia 30332, USA
    J Infect Dis 197:S127-31. 2008
    ..Continued surveillance of the risk and characteristics of breakthrough disease will be needed, to monitor the effect of the new 2-dose vaccine recommendation for children...
  101. ncbi Risk of herpes zoster in adults immunized with varicella vaccine
    Sophie Hambleton
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Infect Dis 197:S196-9. 2008
    ..00 case/1000 person-years. Overall, the incidence of HZ in this cohort, therefore, is similar to published data for the US population in the prevaccine era...

Research Grants31

  1. BEHAVIORAL INTERVENTION FOR HERPES ZOSTER RISK IN AGING
    Michael Irwin; Fiscal Year: 2003
    ....
  2. Molecular Epidemiology of Fatal Prostate Cancer
    Sheila Weinmann; Fiscal Year: 2006
    ..The case-control study design will provide maximum statistical power for analysis of these relationships, particularly in the important African-American subgroup. ..
  3. VZV Receptors and Infective Mechanisms
    Anne Gershon; Fiscal Year: 2007
    ..It may also make it possible to develop a safer and more efficacious vaccine. ..
  4. PEDIATRICS AIDS CLINICAL TRIALS GROUP
    Anne Gershon; Fiscal Year: 2006
    ..We have competent, outstanding staff whose aim is not only to provide compassionate medical care to HIV-infected patients but also to perform meaningful and useful research on prevention and treatment of HIV infection. ..
  5. Clinical Performance Measures & Outcomes in Adolescents
    Susan Furth; Fiscal Year: 2005
    ..abstract_text> ..
  6. Assessing Functional Outcomes in Adolescent with ESRD
    Susan Furth; Fiscal Year: 2002
    ..This experience will give Dr. Furth the tools she needs to develop into an independent clinical investigator in a nurturing academic environment. ..
  7. ASSESSING PATIENT OUTCOMES IN PEDIATRIC ESRD
    Susan Furth; Fiscal Year: 2003
    ..Furth the tools she needs to develop into an independent clinical investigator in a nurturing academic environment. ..
  8. ONTOGENY OF MEASLES IMMUNITY IN INFANTS
    Ann Arvin; Fiscal Year: 2006
    ..Understanding the maturation of host responses to viral antigens during the first year of life has general relevance for vaccine strategies in infancy. ..
  9. DETERMINING/UNDERSTANDING BARRIERS TO ADULT IMMUNIZATION
    Richard Zimmerman; Fiscal Year: 2001
    ..This project will furnish relevant, up-to-date to enhance policy planning, practice management and medical education. ..
  10. Using MEPS Data to Inform Public-Plan Consumerism
    Matthew Davis; Fiscal Year: 2007
    ..Findings will have immediate relevance for implementation of the HOA projects and other consumerism efforts. [unreadable] [unreadable] [unreadable]..
  11. THE EFFECTIVENESS OF VACCINES IN CLINICAL PRACTICE
    Eugene Shapiro; Fiscal Year: 2004
    ..Shapiro to review their progress and to help them develop their own studies as well as to develop strategies for the development of their careers. ..
  12. Pilot Study of Automated Surveillance to Measure Burden
    Paul Kilgore; Fiscal Year: 2007
    ..We will assess the potential use of the phone/web-based case reporting system for measuring the impact of health interventions including vaccines. [unreadable] [unreadable] [unreadable]..
  13. A RANDOMIZED CONTROLLED TRIAL OF ECHINACEA IN CHILDREN
    James Taylor; Fiscal Year: 2001
    ..abstract_text> ..
  14. Training in Patient-Oriented Research for Physicians
    Eugene Shapiro; Fiscal Year: 2006
    ..Ultimately, the Yale CRS Program will help to increase the pool of physician-investigators who will be uniquely poised to conduct research to directly improve the health of all Americans. [unreadable] [unreadable] [unreadable]..
  15. Effectiveness of Varicella Vaccine in Clinical Practice
    Eugene Shapiro; Fiscal Year: 2006
    ..abstract_text> ..
  16. DEPRESSION AND TRIAL OF VARICELLA VACCINE IN THE ELDERLY
    Michael Irwin; Fiscal Year: 2003
    ....
  17. The Feasibility of Assessing the Prevalence of Rickets
    James Taylor; Fiscal Year: 2006
    ..In addition to assessing possible methodologies for the larger project, the preliminary study is designed to yield standalone results with important implications. [unreadable] [unreadable] [unreadable]..
  18. Parental Involvement Laws and Reproductive Outcomes
    Theodore Joyce; Fiscal Year: 2006
    ..Teens who do not involve their parents may take longer to obtain an abortion either out of state or through a judicial bypass. Thus, we expect PI laws to increase the rate of second trimester abortions among minors. ..
  19. RESEARCH PERSPECTIVES IN PNI, TRAINEE TRAVEL
    Michael Irwin; Fiscal Year: 2006
    ..abstract_text> ..
  20. Trainee-Focusted Training for Research Integrity
    Steven Jacobsen; Fiscal Year: 2003
    ..6. Identify high frequency perceptions or frames of reference, which are substantially at odds with accepted research norms and begin designing better interventions to alter them. ..
  21. Cocaine Dependence: EEG Sleep and Cytokines
    Michael Irwin; Fiscal Year: 2005
    ..abstract_text> ..
  22. Challenging Life Events in Older Persons
    TIMOTHY DAALEMAN; Fiscal Year: 2005
    ..e. social support, mental health status. Secondary aims include learning how a baseline measure of patient spirituality predicts future death attitudes and discussions of advance care planning. ..
  23. ELDER ABUSE, ETHNICITY, AND HEALTHCARE SETTINGS
    Michael Rodriguez; Fiscal Year: 2005
    ....
  24. VACCINATION AGAINST HERPES SIMPLEX VIRUS
    BARRY ROUSE; Fiscal Year: 2004
    ..Our results should be applicable to the future design of vaccines against HSV and may have application to other situations that require immunomodulation. ..
  25. IMMUNITY MECHANISMS IN HERPESVIRUS INFECTIONS
    BARRY ROUSE; Fiscal Year: 2005
    ..Our experiments may identify better methods of generating protective immunity against HSV. ..
  26. Alcoholism: Sleep and Cytokines in African Americans
    Michael Irwin; Fiscal Year: 2005
    ..g., cytokine antagonists) for sleep disturbance in alcoholism. ..
  27. Sleep and Immune Mechanisms in Rheumatoid Arthritis
    Michael Irwin; Fiscal Year: 2009
    ..Results from this study will guide the development of interventions that target disordered sleep with potential effects on disability in RA. ..
  28. Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms
    Michael R Irwin; Fiscal Year: 2010
    ..This project will constitute the first, randomized controlled clinical trial of the effects of TCC on sleep outcomes in breast cancer survivors, and will advance psychobiological models of insomnia treatment mechanisms. ..
  29. ANTIGENIC DETERMINANTS OF VARICELLA VIRUS
    Charles Grose; Fiscal Year: 2006
    ..These proposed VZV studies will provide further insight into the multiple functions of gE and the gE:gI complex. ..