cosmetics

Summary

Summary: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)

Top Publications

  1. ncbi A gas chromatography-mass spectrometric method to determine skin-whitening agents in cosmetic products
    Alberto Chisvert
    Departamento de Quimica Analitica, Facultad de Quimica, Universidad de Valencia, Doctor Moliner Street, 50, 46100 Burjassot, Valencia, Spain
    Talanta 81:530-6. 2010
  2. pmc Endocrine disruptors and asthma-associated chemicals in consumer products
    Robin E Dodson
    Silent Spring Institute, Newton, Massachusetts 02458, USA
    Environ Health Perspect 120:935-43. 2012
  3. ncbi From miso, saké and shoyu to cosmetics: a century of science for kojic acid
    Ronald Bentley
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nat Prod Rep 23:1046-62. 2006
  4. ncbi Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics
    Shinya Kato
    Laboratory of Cell Death Control BioTechnology, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 562, Nanatsuka, Shobara, Hiroshima 727 0023, Japan
    J Nanosci Nanotechnol 10:6769-74. 2010
  5. ncbi Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010
    Sarah Adler
    Centre for Documentation and Evaluation of Alternatives to Animal Experiments ZEBET, Federal Institute for Risk Assessment BfR, Berlin, Germany
    Arch Toxicol 85:367-485. 2011
  6. ncbi Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan
    Arshad Mehmood Abbasi
    Department of Plant Sciences, Quaid i Azam University, Islamabad 45320, Pakistan
    J Ethnopharmacol 128:322-35. 2010
  7. ncbi Assessment of lead in cosmetic products
    Iman Al-Saleh
    Environmental Health Section, Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, P O Box 3354, Riyadh 11211, Saudi Arabia
    Regul Toxicol Pharmacol 54:105-13. 2009
  8. ncbi Exposure patterns of UV filters, fragrances, parabens, phthalates, organochlor pesticides, PBDEs, and PCBs in human milk: correlation of UV filters with use of cosmetics
    Margret Schlumpf
    GREEN Tox and Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Chemosphere 81:1171-83. 2010
  9. ncbi Determination of total lead in lipstick: development and validation of a microwave-assisted digestion, inductively coupled plasma-mass spectrometric method
    Nancy M Hepp
    Office of Cosmetics and Colors, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, MD 20740, USA
    J Cosmet Sci 60:405-14. 2009
  10. ncbi Optical characteristics of titanium oxide interference film and the film laminated with oxides and their applications for cosmetics
    Takahiro Kaida
    Nihon Koken Kogyo Company, Ltd, Tachikawa shi, Japan
    J Cosmet Sci 55:219-20. 2004

Detail Information

Publications280 found, 100 shown here

  1. ncbi A gas chromatography-mass spectrometric method to determine skin-whitening agents in cosmetic products
    Alberto Chisvert
    Departamento de Quimica Analitica, Facultad de Quimica, Universidad de Valencia, Doctor Moliner Street, 50, 46100 Burjassot, Valencia, Spain
    Talanta 81:530-6. 2010
    ..kojic acid, azelaic acid and arbutin) and two forbidden (resorcinol and hydroquinone) skin-whitening agents in cosmetics. The method is based on gas chromatography coupled with mass spectrometric detection, which allows the two ..
  2. pmc Endocrine disruptors and asthma-associated chemicals in consumer products
    Robin E Dodson
    Silent Spring Institute, Newton, Massachusetts 02458, USA
    Environ Health Perspect 120:935-43. 2012
    ..Laboratory and human studies raise concerns about endocrine disruption and asthma resulting from exposure to chemicals in consumer products. Limited labeling or testing information is available to evaluate products as exposure sources...
  3. ncbi From miso, saké and shoyu to cosmetics: a century of science for kojic acid
    Ronald Bentley
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nat Prod Rep 23:1046-62. 2006
    ..It was one of the first secondary metabolites to have its biosynthetic pathway studied by the isotope tracer technique, and, more recently, has been of interest as a skin lightening agent. There are 112 references...
  4. ncbi Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics
    Shinya Kato
    Laboratory of Cell Death Control BioTechnology, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 562, Nanatsuka, Shobara, Hiroshima 727 0023, Japan
    J Nanosci Nanotechnol 10:6769-74. 2010
    ..We suggest that LF-SQ could be used as an active ingredient for wrinkle-care cosmetics.
  5. ncbi Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010
    Sarah Adler
    Centre for Documentation and Evaluation of Alternatives to Animal Experiments ZEBET, Federal Institute for Risk Assessment BfR, Berlin, Germany
    Arch Toxicol 85:367-485. 2011
    The 7th amendment to the EU Cosmetics Directive prohibits to put animal-tested cosmetics on the market in Europe after 2013...
  6. ncbi Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan
    Arshad Mehmood Abbasi
    Department of Plant Sciences, Quaid i Azam University, Islamabad 45320, Pakistan
    J Ethnopharmacol 128:322-35. 2010
    The present investigation is an attempt to find out ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics.
  7. ncbi Assessment of lead in cosmetic products
    Iman Al-Saleh
    Environmental Health Section, Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, P O Box 3354, Riyadh 11211, Saudi Arabia
    Regul Toxicol Pharmacol 54:105-13. 2009
    ..This has drawn our attention to assess the safety of various cheap brands of cosmetics sold at 2-riyals stores in Saudi market that are imported from countries where safety regulations are poorly ..
  8. ncbi Exposure patterns of UV filters, fragrances, parabens, phthalates, organochlor pesticides, PBDEs, and PCBs in human milk: correlation of UV filters with use of cosmetics
    Margret Schlumpf
    GREEN Tox and Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Chemosphere 81:1171-83. 2010
    ..Our data emphasize the need for analyses of complex mixtures to obtain more information on inter-individual and temporal variability of human exposure to different types of chemicals...
  9. ncbi Determination of total lead in lipstick: development and validation of a microwave-assisted digestion, inductively coupled plasma-mass spectrometric method
    Nancy M Hepp
    Office of Cosmetics and Colors, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, MD 20740, USA
    J Cosmet Sci 60:405-14. 2009
    ..This method will be useful for the FDA and industry in helping to ensure the safety of cosmetic products...
  10. ncbi Optical characteristics of titanium oxide interference film and the film laminated with oxides and their applications for cosmetics
    Takahiro Kaida
    Nihon Koken Kogyo Company, Ltd, Tachikawa shi, Japan
    J Cosmet Sci 55:219-20. 2004
  11. ncbi Categorization framework to aid exposure assessment of nanomaterials in consumer products
    Steffen Foss Hansen
    Department of Environmental Engineering, NanoDTU Environment and Health, Technical University of Denmark, DTU Building 113, Kgs Lyngby 2800, Denmark
    Ecotoxicology 17:438-47. 2008
    ..The application of sun lotion containing 2% nanoparticles result in an exposure of 56.7 mg kg(-1) bw d(-1) for a 2-year-old child, if the amounts applied correspond to the European Commission recommendations on use of sunscreen...
  12. ncbi Novel cosmetic delivery systems: an application update
    V B Patravale
    Department of Pharmaceutical Sciences and Technology, University Institute of Chemical Technology, Mumbai 400 019, India
    Int J Cosmet Sci 30:19-33. 2008
    ..Functional ingredients and innovative delivery systems are driving the new product development in the field of cosmetics. A significant number of innovative formulations are now being used in personal care with real consumer-..
  13. ncbi European consumer exposure to cosmetic products, a framework for conducting population exposure assessments Part 2
    B Hall
    L Oreal, Worldwide Safety Evaluation, Asnières sur Seine, France
    Food Chem Toxicol 49:408-22. 2011
    ..date and largely confirm the current exposure parameters concerning some 95% of the estimated daily exposure to cosmetics use in the EU...
  14. ncbi Recent progresses in application of fullerenes in cosmetics
    Marko Lens
    King s College, St Thomas s Hospital, Westminster Bridge Road, London SE1 7EH, UK
    Recent Pat Biotechnol 5:67-73. 2011
    ..Published evidence on biological activities of fullerenes relevant for their application in cosmetics use and examples of published patents are presented...
  15. ncbi Spectroscopic detection of health hazardous contaminants in lipstick using Laser Induced Breakdown Spectroscopy
    M A Gondal
    Physics Department and Center of Excellence in Nanotechnology, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia
    J Hazard Mater 175:726-32. 2010
    ..For this purpose, special treatment of the lipstick samples was necessary to analyze with our LIBS method...
  16. pmc Concentrations and potential health risks of metals in lip products
    Sa Liu
    Environmental Health Sciences Division, School of Public Health, University of California, Berkeley, Berkeley, California 94720 7360, USA
    Environ Health Perspect 121:705-10. 2013
    ..Metal content in lip products has been an issue of concern...
  17. ncbi European consumer exposure to cosmetic products, a framework for conducting population exposure assessments
    B Hall
    L Oreal, Worldwide Safety Evaluation, River Plaza 25 29 quai Aulagnier, 92600 Asnières sur Seine, France
    Food Chem Toxicol 45:2097-108. 2007
    ..The results largely confirm the exposure parameters currently used by the cosmetic industry. Design of this study could serve as a model for future assessments of population exposure to chemicals in products other than cosmetics.
  18. ncbi Accumulation of mercury in ovaries of mice after the application of skin-lightening creams
    Iman Al-Saleh
    Biological and Medical Research Department, King Faisal Specialist Hospital, Riyadh, Saudi Arabia
    Biol Trace Elem Res 131:43-54. 2009
    ..Alternatively, public health authorities should encourage more reliance on prescribed creams for the treatment of skin pigmentation problems...
  19. ncbi Investigation of lead contents in lipsticks by solid sampling high resolution continuum source electrothermal atomic absorption spectrometry
    Sema Gunduz
    Istanbul Technical University, Faculty of Science and Letters, Department of Chemistry, 34469 Maslak Istanbul, Turkey
    Regul Toxicol Pharmacol 65:34-7. 2013
    ..The lead in 25 lipstick samples with different properties were 0.11-4.48 ng mg(-1) which were not significantly different from those (<0.026-7.19 ng mg(-1)) reported by FDA for around 400 samples...
  20. ncbi Novel technologies and an overall strategy to allow hazard assessment and risk prediction of chemicals, cosmetics, and drugs with animal-free methods
    Marcel Leist
    Centre for Alternatives to Animal Testing, CAAT Europe, University of Konstanz, Germany
    ALTEX 29:373-88. 2012
    ..The overall hazard and risk assessment strategy integrating these different examples has been compiled in a graphical work flow...
  21. ncbi Usage patterns of personal care products: important factors for exposure assessment
    Jacqueline W H Biesterbos
    Radboud University Medical Centre, Department for Health Evidence, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Food Chem Toxicol 55:8-17. 2013
    ..As expected, the participants used several PCPs simultaneously. The database yields important personalized exposure factors which can be used in aggregate consumer exposure assessment for substances that are components of PCPs...
  22. pmc Metabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytes
    P Tucci
    Medical Research Council, Toxicology Unit, Leicester University, Leicester, UK
    Cell Death Dis 4:e549. 2013
    ..No other morphological changes were detected after 24-h exposure consistent with a specific role of mitochondria in this response...
  23. ncbi Potential exposure of German consumers to engineered nanoparticles in cosmetics and personal care products
    Christiane Lorenz
    Institute for Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland
    Nanotoxicology 5:12-29. 2011
    ..Along with toxicological data, exposure estimates are essential for assessing risk. Currently, cosmetics and personal care products (C&PCP) represent the largest ENP-containing consumer product class on the market...
  24. ncbi Toxicological profile of diethyl phthalate: a vehicle for fragrance and cosmetic ingredients
    A M Api
    Research Institute for Fragrance Materials Inc, Two University Plaza, Suite 406, Hackensack, NJ 07601, USA
    Food Chem Toxicol 39:97-108. 2001
    ..75 mg/kg/day oral exposure) indicates no significant toxic liability for the use of DEP in fragrances and cosmetic products...
  25. ncbi Formulation and in vitro evaluation of a cosmetic emulsion from almond oil
    Naveed Akhtar
    Faculty of Pharmacy and Alternative Medicine, Department of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
    Pak J Pharm Sci 21:430-7. 2008
    ....
  26. ncbi Development of the EpiOcular(TM) eye irritation test for hazard identification and labelling of eye irritating chemicals in response to the requirements of the EU cosmetics directive and REACH legislation
    Yulia Kaluzhny
    MatTek Corporation, Ashland, MA 01721, USA
    Altern Lab Anim 39:339-64. 2011
    The recently implemented 7th Amendment to the EU Cosmetics Directive and the EU REACH legislation have heightened the need for in vitro ocular test methods...
  27. ncbi Usage pattern of personal care products in California households
    Xiangmei May Wu
    Department of Public Health Sciences, University of California, Davis, CA 95616, USA
    Food Chem Toxicol 48:3109-19. 2010
    ..This information will be valuable for exposure and risk assessments...
  28. ncbi Structural degradation at the surface of a TiO(2)-based nanomaterial used in cosmetics
    Melanie Auffan
    CEREGE UMR 6635 CNRS Aix Marseille Universite, Europole de l Arbois, Aix en Provence, France
    Environ Sci Technol 44:2689-94. 2010
    ..We focused here on a hydrophobic TiO(2) nanoparticle-based formulation used in cosmetics: T-Lite SF...
  29. ncbi Exposure data for cosmetic products: lipstick, body lotion, and face cream
    L J Loretz
    Cosmetic, Toiletry, and Fragrance Association, 1101 17th Street NW, Suite 300, Washington, DC 20036, USA
    Food Chem Toxicol 43:279-91. 2005
    ..The effect of product preference on use practices was also investigated. This study provides current cosmetic exposure information for commonly used products which will be useful for risk assessment purposes...
  30. ncbi Engineered inorganic nanoparticles and cosmetics: facts, issues, knowledge gaps and challenges
    Johann W Wiechers
    Independent Consultant for Cosmetic Science, JW Solutions, Gasthuispolderweg 30, 2807 LL Gouda, The Netherlands
    J Biomed Nanotechnol 6:408-31. 2010
    ..concerning the safety and environmental impact of ENPs used in cosmetics. This review paper seeks to address the twin concerns of the safety of cosmetics and the potential environmental ..
  31. ncbi Ultrasound-assisted emulsification of cosmetic samples prior to elemental analysis by different atomic spectrometric techniques
    I Lavilla
    Departamento de Quimica Analitica y Alimentaria, Area de Quimica Analitica, Facultad de Quimica, Universidad de Vigo, As Lagoas Marcosende s n, 36310 Vigo, Spain
    Talanta 80:109-16. 2009
    ..Microwave-assisted digestion and Inductively Coupled Plasma Mass Spectrometry were used for comparison purposes. Relative standard deviations from analysis of five independent emulsions were less than 9% in all cases...
  32. ncbi Safety assessment of personal care products/cosmetics and their ingredients
    Gerhard J Nohynek
    L Oreal R and D, Global Safety Evaluation, 92600 Asnières, France
    Toxicol Appl Pharmacol 243:239-59. 2010
    ..In the interest of all stakeholders, consumers, regulatory bodies and producers, there is an urgent need for an international harmonization on the status and safety requirements of these products and their ingredients...
  33. ncbi Silver nanoparticles as a safe preservative for use in cosmetics
    Satoshi Kokura
    Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Nanomedicine 6:570-4. 2010
    ..These results suggest that Ag nanoparticles may have potential for use as a preservative in cosmetics. From the clinical editor: In this study, the effects of recently synthesized Ag nanoparticles were investigated ..
  34. ncbi Lip colour affects perceived sex typicality and attractiveness of human faces
    Ian D Stephen
    Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK
    Perception 39:1104-10. 2010
    ..The association between lip colour contrast and attractiveness in women's faces may be attributable to its association with oxygenated blood perfusion indicating oestrogen levels, sexual arousal, and cardiac and respiratory health...
  35. ncbi Lead and traditional Moroccan pharmacopoeia
    N Lekouch
    University Cadi Ayyad, Faculty of Sciences, Department of Biology, Marrakech, Morocco
    Sci Total Environ 280:39-43. 2001
    The use of traditional cosmetics and remedies such as kohl and henna is very common in Morocco, especially among women, children and babies. Kohl is a dangerous eye cosmetic...
  36. ncbi Decorative cosmetics improve the quality of life in patients with disfiguring skin diseases
    Wolf Henning Boehncke
    Department of Dermatology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590, Frankfurt Main, Germany
    Eur J Dermatol 12:577-80. 2002
    ..We therefore asked whether the application of decorative cosmetics might increase their quality of life...
  37. pmc Mercury poisoning associated with a Mexican beauty cream
    M M Weldon
    Epidemic Intelligence Service EIS Epidemiology Program Office, CDC Atlanta, GA, USA
    West J Med 173:15-8; discussion 19. 2000
    ....
  38. ncbi Objective evaluation of the efficacy of daily topical applications of cosmetics bases using the hairless mouse model of atopic dermatitis
    Katsuo Matsumoto
    POLA Laboratories, Kashio cho, Totsuka ku, Yokohama, Kanagawa, Japan
    Skin Res Technol 11:209-17. 2005
    ..To elucidate the mechanisms underlying the clinical effectiveness of these newer treatments, we used our recently established hairless mouse model of AD...
  39. ncbi Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant
    Linda Loretz
    Cosmetic, Toiletry, and Fragrance Association, 1101 17th Street NW, Suite 300, Washington, DC 20036, USA
    Food Chem Toxicol 44:2008-18. 2006
    ..Six widely used personal care product types were included in the studies. Five of the products were cosmetics (spray perfume, hairspray, liquid foundation, shampoo, body wash) and one product was a cosmetic/over-the-..
  40. ncbi Efficacy of lanolin and bovine type I collagen in the treatment of childhood anal fissures: a prospective, randomized, controlled clinical trial
    Behçet Ilker Büyükyavuz
    Department of Pediatric Surgery, Suleyman Demirel University Medical School, 32260, Isparta, Turkey
    Surg Today 40:752-6. 2010
    ..We designed an open-labeled, prospective, randomized, controlled clinical trial to test the efficacy of topical lanolin ointment (PureLan) and bovine type I collagen spray (Gelfix) in the treatment of childhood anal fissures...
  41. ncbi Study of sensory properties of emollients used in cosmetics and their correlation with physicochemical properties
    Maria Emma Parente
    Cátedra de Química Cosmética, Facultad de Quimica, Universidad de la Republica, Montevideo, Uruguay
    J Cosmet Sci 56:175-82. 2005
    ..PLS revealed that emollient sensory attributes could be well predicted by instrumental measurements...
  42. ncbi Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients
    R Kroes
    Institute for Risk Assessment Sciences, Utrecht University, c o Seminariehof 38, NL 3768 EE Soest, The Netherlands
    Food Chem Toxicol 45:2533-62. 2007
    ..Overall the TTC approach provides a useful additional tool for the safety evaluation of cosmetic ingredients and impurities of known chemical structure in the absence of chemical-specific toxicology data...
  43. ncbi Formaldehyde-releasers in cosmetics in the USA and in Europe
    Anton C de Groot
    Schipslootweg 5, 8351 HV Wapserveen, The Netherlands
    Contact Dermatitis 62:221-4. 2010
    Frequencies of sensitization to formaldehyde among US patients patch tested for suspected contact dermatitis are higher than in Europe. Cosmetics are an important source of contact with formaldehyde.
  44. ncbi [Improvement of local lymph node assay for cosmetics safety evaluation]
    Zhen Liu
    Department of Toxicology, The Second Military Medicine University, Shanghai 200433, China
    Wei Sheng Yan Jiu 38:585-9. 2009
    ..To improve the local lymph node assay (LLNA) as an alternative method to detect chemicals for both sensitization and irritation...
  45. ncbi Safety of botanical ingredients in personal care products/cosmetics
    Eric Antignac
    L Oreal Research and Innovation, Global Safety Evaluation, Asnières, France
    Food Chem Toxicol 49:324-41. 2011
    ..Pragmatic approaches for quality and safety standards of botanical ingredients are needed; consumer safety should be the first objective of conventional and botanical PCP ingredients...
  46. ncbi Lipopeptides in cosmetics
    M Kanlayavattanakul
    School of Cosmetic Science, Mae Fah Luang University, Chiangrai, Thailand
    Int J Cosmet Sci 32:1-8. 2010
    Lipopeptides are biosurfactants extensively used in cosmetics. The consumption of cosmetics containing lipopeptides is increasing as a result of the exceptional surface properties and diverse biological activities of lipopeptides which ..
  47. ncbi Combining high-performance liquid chromatography with on-line microdialysis sampling for the simultaneous determination of ascorbyl glucoside, kojic acid, and niacinamide in bleaching cosmetics
    Cheng Hui Lin
    Department of Biological Engineering, Yung Ta Institute of Technology, Pingtung, Taiwan
    Anal Chim Acta 581:102-7. 2007
    ..the contents of ascorbyl glucoside (AA-2G), kojic acid (KA), and niacinamide (VitB(3)) in commercial bleaching cosmetics. Our results indicate that AA-2G, KA, and VitB(3) separated well within 4...
  48. ncbi Frequency of dermatoses associated with cosmetics
    Ida Duarte
    Sector of Allergy and Phototherapy, Clinic of Dermatology, Santa Casa de Sao Paulo Hospital and School of Medicine, Sao Paulo, Brazil
    Contact Dermatitis 56:211-3. 2007
    The objectives of this study were (i) to determine the frequency of dermatoses caused by use of cosmetics in patients with specific complaints of reaction to cosmetic products, and (ii) to observe the main skin conditions frequently ..
  49. ncbi Hydrolysed wheat proteins present in cosmetics can induce immediate hypersensitivities
    Michel Lauriere
    UMR INRA INA PG de Chimie Biologique, Centre de Recherche de Grignon, 78850 Thiverval Grignon, France
    Contact Dermatitis 54:283-9. 2006
    b>Cosmetics containing hydrolysed wheat proteins (HWP) can induce rare but severe allergic reactions. 9 patients, all females without common wheat allergy, but with contact urticaria to such cosmetics, were studied...
  50. ncbi Use of the Reviscometer for measuring cosmetics-induced skin surface effects
    M Paye
    Colgate Palmolive R and D, Milmort, Belgium
    Skin Res Technol 13:343-9. 2007
    ..The Reviscometer RVM600 that measures resonance running time (RRT) has been shown to be inversely related to the skin stiffness. However, very few publications describe the use of this instrument for testing the effect of cosmetic products...
  51. ncbi Chemiluminescence determination of ferulic acid by flow-injection analysis using cerium(IV) sensitized by rhodamine 6G
    Ju Peng Wang
    School of Chemistry and Chemical Engineering, Chongqing Municipal Key Laboratory of Luminescence and Real Time Analysis, Southwest University, Chongqing 400715, PR China
    Spectrochim Acta A Mol Biomol Spectrosc 71:204-8. 2008
    ..The relative standard deviation was 2.4% for 10 replicate analyses of 1.0 x 10(-5) mol l(-1) ferulic acid. The proposed method was applied to the determination of ferulic acid in Taita Beauty Essence samples with satisfactory results...
  52. ncbi Simultaneous determination of heavy metals in cosmetic products
    So Mi Lee
    Amore Pacific Corporation, 314 1 Bora dong, Giheung gu, Yongin si, Gyeonggi Do, 446 729, Republic of Korea
    J Cosmet Sci 59:441-8. 2008
    ..The new method was applied to analyze the amount of heavy metals contained in 22 cosmetic products and 11 coloring agents...
  53. ncbi Cosmetics Europe multi-laboratory pre-validation of the SkinEthic™ reconstituted human corneal epithelium test method for the prediction of eye irritation
    N Alepee
    L Oreal Research and Innovation, Aulnay sous Bois, France
    Toxicol In Vitro 27:1476-88. 2013
    b>Cosmetics Europe, The Personal Care Association, known as Colipa before 2012, conducted a program of technology transfer and assessment of Within/Between Laboratory (WLV/BLV) reproducibility of the SkinEthic™ Reconstituted Human ..
  54. ncbi An expert consortium review of the EC-commissioned report "alternative (Non-Animal) methods for cosmetics testing: current status and future prospects - 2010"
    Thomas Hartung
    Johns Hopkins University, Bloomberg School of Public Health, Center for Alternatives to Animal Testing, Baltimore, MD 21205, USA
    ALTEX 28:183-209. 2011
    The European cosmetics legislation foresees a review in 2011 and possible postponement of the 2013 marketing ban to enforce the testing ban for systemic and repeated-dose animal tests...
  55. pmc Evaluating beauty care provided by the hospital to women suffering from breast cancer: qualitative aspects
    Philippe Amiel
    Institut de Cancerologie Gustave Roussy, 39, rue Camille Desmoulins, 94805, Villejuif Cedex, France
    Support Care Cancer 17:839-45. 2009
    ....
  56. ncbi Analysis of aliphatic dicarboxylic acids in pharmaceuticals and cosmetics by liquid chromatography (HPLC) with fluorescence detection
    R Gatti
    Department of Pharmaceutical Sciences, University of Bologna, Italy
    J Pharm Biomed Anal 13:589-95. 1995
    ..The proposed methods proved to be suitable for the quality control of various complex pharmaceutical and cosmetic formulations of the azelaic acid and meglutol...
  57. ncbi Aromatase inhibiting and combined estrogenic effects of parabens and estrogenic effects of other additives in cosmetics
    J A van Meeuwen
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Toxicol Appl Pharmacol 230:372-82. 2008
    ..Our calculation for the extra estrogen burden due to exposure to parabens, phthalates and polycyclic musks indicates an insignificant estrogenic load relative to the endogenous or therapeutic estrogen burden...
  58. ncbi [Medical corrective make-up in post- chemotherapy]
    C Merial-Kieny
    Laboratoires Dermatologiques Avène Les Cauquillous, 81506 Lavaur cedex, France
    Ann Dermatol Venereol . 2008
    ..The aim of this study was to evaluate the tolerance and the satisfaction of patients needing medical make up to hide the cutaneous side effects induced by chimiotherapy and to improve self-esteem...
  59. ncbi Exposure data for cosmetic products: facial cleanser, hair conditioner, and eye shadow
    L J Loretz
    Cosmetic, Toiletry, and Fragrance Association, Washington, DC 20036, USA
    Food Chem Toxicol 46:1516-24. 2008
    ..6, 1.1, and 1.2, respectively. This study provides an estimate of current exposure information for commonly used products which will be useful for risk assessment purposes...
  60. ncbi Synthetic musks in blood of healthy young adults: relationship to cosmetics use
    H P Hutter
    Institute of Environmental Health, Center for Public Health, Medical University of Vienna, Kinderspitalgasse 15, A 1095, Vienna, Austria
    Sci Total Environ 407:4821-5. 2009
    ..Study participants also completed a questionnaire on the use of cosmetics, about nutrition and other life-style aspects...
  61. ncbi Refining aggregate exposure: example using parabens
    Christina E Cowan-Ellsberry
    The Procter and Gamble Company, Cincinnati, OH, USA
    Regul Toxicol Pharmacol 55:321-9. 2009
    ..Comparison to the 95th percentile of these data showed that these refined estimates were still conservative by factors of 2-92. All of our refined estimates of aggregate exposure are less than the ADI of 10mg/kg/day for parabens...
  62. ncbi Patterns of cosmetic contact allergy
    Mari Paz Castanedo-Tardan
    Department of Medicine, Section of Dermatology, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA
    Dermatol Clin 27:265-80, vi. 2009
    ..Once the offending allergen is identified, an avoidance regimen should be established to avoid further exposure...
  63. ncbi Lipid nanoparticles as novel delivery systems for cosmetics and dermal pharmaceuticals
    Carmelo Puglia
    University of Catania, Carmelo Puglia, Department of Drug Sciences, Faculty of Pharmacy, Catania, Italy
    Expert Opin Drug Deliv 9:429-41. 2012
    ..Solid lipid nanoparticles (SLN) and the newest nanostructured lipid carriers (NLC) show important advantages for dermal application of cosmetics and pharmaceuticals.
  64. ncbi Contact allergy to the 26 specific fragrance ingredients to be declared on cosmetic products in accordance with the EU cosmetics directive
    Maria V Heisterberg
    Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, National Allergy Research Centre, 2900 Hellerup, Denmark
    Contact Dermatitis 65:266-75. 2011
    Fragrance ingredients are a frequent cause of allergic contact dermatitis. The EU Cosmetics Directive states that 26 specific fragrance ingredients, known to cause allergic contact dermatitis, must be declared on the ingredient lists of ..
  65. pmc Cosmetics as a feature of the extended human phenotype: modulation of the perception of biologically important facial signals
    Nancy L Etcoff
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 6:e25656. 2011
    ..Here, we investigate one tool, the use of color cosmetics. In two studies, we asked viewers to rate the same female faces with or without color cosmetics, and we varied ..
  66. ncbi Molecularly imprinted layer-coated silica nanoparticles for selective solid-phase extraction of bisphenol A from chemical cleansing and cosmetics samples
    Rong Zhu
    School of Pharmacy, Nanjing Medical University, Hanzhong Road 140, Nanjing, Jiangsu 210029, PR China
    Anal Chim Acta 658:209-16. 2010
    ..The BPA-imprinted silica nanoparticles were successfully used in SPE to selectively enrich and determine BPA from shampoo, bath lotion and cosmetic cream samples...
  67. ncbi Low molecular weight cyclic volatile methylsiloxanes in cosmetic products sold in Canada: implication for dermal exposure
    Rong Wang
    Exposure and Biomonitoring Division, Health Canada, Ottawa, ON, Canada
    Environ Int 35:900-4. 2009
    Low molecular weight cyclic volatile methylsiloxane (cVMS) compounds have been used in a variety of cosmetics and personal care products and many other consumer products...
  68. ncbi Volatile pollutants emitted from selected liquid household products
    Ki Dong Kwon
    Department of Indoor Environment, National Institute of Environment Research, Incheon, South Korea
    Environ Sci Pollut Res Int 15:521-6. 2008
    ..Consequently, the current study evaluated the emission composition for 42 liquid household products sold in Korea, focusing on five product classes (deodorizers, household cleaners, color removers, pesticides, and polishes)...
  69. ncbi Final report of the safety assessment of Kojic acid as used in cosmetics
    Christina L Burnett
    Cosmetic Ingredient Review, Washington, DC 20036, USA
    Int J Toxicol 29:244S-73. 2010
    ..available human sensitization data supported the safety of kojic acid at a use concentration of 2% in leave-on cosmetics. Kojic acid depigmented black guinea pig skin at a concentration of 4%, but this effect was not seen at 1%...
  70. ncbi Changes in European legislation make it timely to introduce a transparent market surveillance system for cosmetics
    Marie Lodén
    Research and Development, ACO HUD NORDIC AB, Upplands Vasby, Sweden
    Acta Derm Venereol 87:485-92. 2007
    Marketing of cosmetics often makes strong claims linked to active ingredients...
  71. ncbi Carotenoids and polyphenols in nutricosmetics, nutraceuticals, and cosmeceuticals
    Talita Pizza Anunciato
    Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brasil
    J Cosmet Dermatol 11:51-4. 2012
    ..As a recent result of convergence phenomenon between cosmetics and food industries, nutricosmetics is a blurry area unfamiliar to many consumers and sometimes even to foods ..
  72. ncbi Colored facial cosmetics
    Z D Draelos
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Dermatol Clin 18:621-31. 2000
    Colored cosmetics are an important part of the dermatologic armamentarium...
  73. ncbi Consumer inhalation exposure to formaldehyde from the use of personal care products/cosmetics
    Marc André Lefebvre
    L Oreal, Research and Innovation, 25 29 quai Aulagnier, 92665 Asnières, France
    Regul Toxicol Pharmacol 63:171-6. 2012
    ..4-87 μg/m³). Overall, our data yielded evidence that inhalation of FA from the use of PCP containing FA-releasers poses no risk to human health...
  74. pmc Mercury levels in locally manufactured Mexican skin-lightening creams
    Claudia P Peregrino
    Environmental Department, Advanced Material Research Center, Miguel de Cervantes 120, Chihuahua, Chih 31109, Mexico
    Int J Environ Res Public Health 8:2516-23. 2011
    ..Skin creams containing mercury are still available and commonly used in Mexico and many developing countries, and their contents are poorly controlled...
  75. ncbi Use of fullerenes in cosmetics
    Marko Lens
    King s College, Genetic Epidemiology Unit, St Thomas s Hospital, Lambeth Palace Road, London, UK
    Recent Pat Biotechnol 3:118-23. 2009
    ..In the last few years application of fullerene C(60) and its derivates in cosmetics has been intensively tested. Fullerenes display a wide range of biological activities...
  76. ncbi Are adverse skin reactions to cosmetics underestimated in the clinical assessment of contact dermatitis? A prospective study among 1075 patients attending Swedish patch test clinics
    Magnus Lindberg
    Department of Medicine, Occupational and Environmental Dermatology, Karolinska Institutet, Stockholm, Sweden
    Acta Derm Venereol 84:291-5. 2004
    It is known that cosmetics and skin care products can cause adverse skin reactions. However, the frequency of adverse reactions reported to the Medical Product Agency (MPA) in Sweden is low...
  77. ncbi Use of topical herbal remedies and cosmetics: a questionnaire-based investigation in dermatology out-patients
    M Corazza
    Department of Clinical and Experimental Medicine, Section of Dermatology, University of Ferrara, Ferrara, Italy
    J Eur Acad Dermatol Venereol 23:1298-303. 2009
    Although topical remedies and cosmetics based on herbal ingredients are becoming increasingly popular with the public due to the perception that botanical compounds are safer and healthier than their synthetic counterparts, a large ..
  78. ncbi Marinosomes, marine lipid-based liposomes: physical characterization and potential application in cosmetics
    N Moussaoui
    Laboratoire de Nutrition et Signalisation Cellulaire, ISTAB, Universite Bordeaux I, Avenue des Facultes, F 33405 Cedex, Talence, France
    Int J Pharm 242:361-5. 2002
    ..At low pH (pH 4) or in presence of high calcium concentrations (9 mM), complex structural rearrangements, such as aggregation and size reduction, occurred which were kinetically dependant...
  79. ncbi Validation of HPLC method for the simultaneous and quantitative determination of 12 UV-filters in cosmetics
    M Nyeborg
    Laboratoire COTY LANCASTER, Recherche et développement analytique, 6, avenue Albert II, 98000 Monaco, France
    Int J Cosmet Sci 32:47-53. 2010
    ..UV measurements were carried out at multi-wavelengths, according to the absorption of the analytes...
  80. ncbi Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes
    D J Kirkland
    Covance Laboratories Limited, Otley Road, Harrogate HG3 1PY, UK
    Mutat Res 588:88-105. 2005
    The European Scientific Committee on Cosmetics and Non-Food Products (SCCNFP) guideline for testing of hair dyes for genotoxic/mutagenic/carcinogenic potential has been reviewed...
  81. ncbi Allergic contact dermatitis from cosmetics. Retrospective analysis of 819 patch-tested patients
    L Kohl
    Department of Dermatology, University Hospital St Pierre, Brussels, Belgium
    Dermatology 204:334-7. 2002
    b>Cosmetics have been used since the oldest known civilisations, and nowadays almost everybody resorts to beauty products.
  82. ncbi Safety evaluation of cosmetics in the EU. Reality and challenges for the toxicologist
    Marleen Pauwels
    Dermato Cosmetology and Pharmacognosy, Department of Toxicology, Vrije Universiteit Brussel, Laarbeeklaan 103, B 1090 Brussels, Belgium
    Toxicol Lett 151:7-17. 2004
    ..i) The full responsibility for the safety of cosmetics for human health is placed on the manufacturer, first importer in the EU or marketer...
  83. ncbi Rapid detection of ricin in cosmetics and elimination of artifacts associated with wheat lectin
    Jacqueline Dayan-Kenigsberg
    Unité Biotechnologie, Biochimie des Protéines et Macromolécules, agence française de sécurité sanitaire des produits de santé, 143 boulevard Anatole France, 93285 Saint Denis Cedex, France
    J Immunol Methods 336:251-4. 2008
    Ricin can be detected in cosmetics at 0.005 microg/mL in the analytical sample using lateral flow devices (LFDs). Wheat germ, an ingredient used in skin care products is also a potential source of wheat lectin...
  84. ncbi A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: genotoxicity. A COLIPA analysis
    Stefan Pfuhler
    Procter and Gamble, Miami Valley Laboratories, Cincinnati, OH 45253, USA
    Regul Toxicol Pharmacol 57:315-24. 2010
    ..Due to the 7th amendment to the EU Cosmetics Directive ban on in vivo genotoxicity testing for cosmetics that was enacted March 2009, it is no longer ..
  85. ncbi ECVAM's response to the changing political environment for alternatives: consequences of the European Union chemicals and cosmetics policies
    Thomas Hartung
    ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, 21020 Ispra VA, Italy
    Altern Lab Anim 31:473-81. 2003
    ..In essence, steering groups formed by ECVAM senior staff, and complemented with external experts, will carry out the project management and will coordinate the various inputs...
  86. ncbi Database search for safety information on cosmetic ingredients
    Marleen Pauwels
    Department of Toxicology, Dermato Cosmetology and Pharmacognosy, Vrije Universiteit Brussel, Laarbeeklaan 103, B 1090 Brussels, Belgium
    Regul Toxicol Pharmacol 49:208-16. 2007
    ..It should be mentioned that the search strategies described are equally useful as a starting point for any quest for safety data on chemicals or chemical-related substances in general...
  87. ncbi Methylisothiazolinone, an emerging allergen in cosmetics?
    Juan García-Gavín
    Faculty of Medicine, Department of Dermatology, University of Santiago de Compostela, University Hospital Complex, Spain
    Contact Dermatitis 63:96-101. 2010
    ..In cosmetics, methylisothiazoline (MI) is permitted in a concentration of 100 p.p.m., while 15 p.p.m...
  88. ncbi Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmetics
    Abinash Pratim Saikia
    Department of Biotechnology, Indian Institute of Technology Guwahati, North Guwahati 781039, Assam, India
    J Ethnopharmacol 106:149-57. 2006
    ..paper deals with the medicinal plants used by the people of Assam for curing different skin ailments and for cosmetics. A total of 85 plants belonging to 49 families have been documented for their therapeutic use against skin ..
  89. ncbi Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry
    Maw Rong Lee
    Department of Chemistry, National Chung Hsing University, Taichung 40227, Taiwan
    J Chromatogr A 1120:244-51. 2006
    ..Detection limits are achieved at the level of 4.7-142 ng/g. It was successfully applied to the determination of paraben preservatives and antioxidants in cosmetics without tedious pretreatment.
  90. ncbi Retinoids in cosmeceuticals
    Olivier Sorg
    Clinique de Dermatologie, Geneva University Hospital, Geneva, Switzerland
    Dermatol Ther 19:289-96. 2006
    ....
  91. ncbi A sex difference in facial contrast and its exaggeration by cosmetics
    Richard Russell
    Department of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA 02138, USA
    Perception 38:1211-9. 2009
    ..Application of cosmetics was found to consistently increase facial contrast...
  92. ncbi Applications of microemulsions in cosmetics
    Prapaporn Boonme
    Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Thailand
    J Cosmet Dermatol 6:223-8. 2007
    ..microemulsions were discovered approximately six decades ago, their applications in several fields, including cosmetics, have been increased due to their good appearance, thermodynamic stability, high solubilization power, and ease ..
  93. ncbi Complications of chronic use of skin lightening cosmetics
    Yetunde M Olumide
    Dermatology Unit, Department of Medicine, College of Medicine, Lagos, Nigeria
    Int J Dermatol 47:344-53. 2008
    Skin lightening (bleaching) cosmetics and toiletries are widely used in most African countries. The active ingredients in these cosmetic products are hydroquinone, mercury and corticosteroids...
  94. ncbi [Allergic contact dermatitis to cosmetics containing Melaleuca alternifolia (tea tree oil)]
    T M Fritz
    Dermatologische Klinik, , Suisse
    Ann Dermatol Venereol 128:123-6. 2001
    ..DISCUSSION: The allergic potential of low concentrations of Melaleuca alternifolia is presumed to be low on healthy skin. Photoaged Melaleuca alternifolia must be considered to be a stronger sensitizer...
  95. ncbi Glucosides as unexpected allergens in cosmetics
    A Goossens
    Department of Dermatology, University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium
    Contact Dermatitis 48:164-6. 2003
  96. ncbi Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods
    Hao Yu Shen
    Analysis and Testing Center, Ningbo Institute of Technology, Zhejiang University, Ningbo, Zhejiang, PR China
    J Sep Sci 30:48-54. 2007
    ..The residue level is at 1.22-5289 mg/kg...
  97. ncbi Allergic contact dermatitis to copolymers in cosmetics--case report and review of the literature
    Sarah Quartier
    Department of Dermatology, University Hospital, Catholic University Leuven, B 3000 Leuven, Belgium
    Contact Dermatitis 55:257-67. 2006
    ..Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still unknown...
  98. ncbi Cosmetics in the treatment of acne vulgaris
    Ella L Toombs
    Aesthetic Dermatology of Dupont Circle, Washington, DC 20009, USA
    Dermatol Clin 23:575-81, viii. 2005
    This article describes scenarios of patients who have acne vulgaris have tried over-the-counter products and cosmetics and are disheartened by the persistence of their disease and the resulting scars...
  99. ncbi Human health safety evaluation of cosmetics in the EU: a legally imposed challenge to science
    M Pauwels
    Department of Toxicology, Dermato Cosmetology and Pharmacognosy, Vrije Universiteit Brussel VUB, Laarbeeklaan 103, B 1090 Brussels, Belgium
    Toxicol Appl Pharmacol 243:260-74. 2010
    ..substances, biocides, plant protection products, food additives, medicinal products, and of course also cosmetics. Horizontal legislative texts, on the contrary, cover more general fields such as protection of experimental ..
  100. ncbi A rapid and reliable size-exclusion chromatographic method for determination of kojic dipalmitate in skin-whitening cosmetic products
    Angel Balaguer
    Departamento de Quimica Analitica, Facultad de Quimica, Universidad de Valencia, 46100 Burjassot, Valencia, Spain
    Talanta 75:407-11. 2008
    ..The chromatographic run takes less than 8 min to complete. All these features make the method easy to apply to quality control in the cosmetic industry...
  101. ncbi Possible relation of Tunisian pemphigus with traditional cosmetics: a multicenter case-control study
    Sylvie Bastuji-Garin
    Department of Public Health, Hôpital Henri Mondor AP HP, Universite Paris XII, Creteil, France
    Am J Epidemiol 155:249-56. 2002
    ..factors were significantly associated with pemphigus in multivariate logistic regression analyses: traditional cosmetics (odds ratio (OR) = 4.0, 95% confidence interval (CI): 1.1, 14.8); Turkish baths (OR = 3.2, 95% CI: 1.4, 7...

Research Grants62

  1. Investigating Mechanism of Intracellular Rotational Transport with Optical T
    Jeffrey N Anker; Fiscal Year: 2012
    ..With the increased use of engineered nanoparticles in medicine (diagnostics and therapeutics), electronics, cosmetics, and textiles and the corresponding awareness of the toxicity from such nanoparticles, there is a critical need ..
  2. Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials
    MATTHEW CUSACK; Fiscal Year: 2010
    ..wine, coffee beer, tea) and all materials placed on the subject/patient's skin such as: lotions, perfumes, cosmetics (lipstick, makeup), soaps, shampoos, deodorant, etc...
  3. Absorption, distribution, metabolism, excretion (ADME) of chemicals in mammals
    Rochelle W Tyl; Fiscal Year: 2009
    ..acid (butylparaben, BPB) is widely used as an antioxidant and preservative in foods, pharmaceuticals, and cosmetics. Human exposure can occur via inhalation, ingestion, or dermal contact...
  4. Field Validation of New XRF Analyzers: Assessing Personal Exposure to Metals
    PATRICK JEREMY PARSONS; Fiscal Year: 2012
    ..g., cosmetics, personal hygiene products) and matrices (e.g...
  5. HDAC Inhibitors Inspired by Natural Products
    Dennis L Wright; Fiscal Year: 2012
    ..valued for antibacterial and antiproliferative activity and are currently used in numerous topical agents and cosmetics. The composition of these extracts was studied in the early 1940s, leading to the identification of an unusual ..
  6. Structural and functional studies of botulinum neurotoxin
    Rongsheng Jin; Fiscal Year: 2013
    ..2001;Gill, 1982). Paradoxically, BoNT-containing medicines and cosmetics, such as Botox(R), Dysport(R), Xeomin(R), CBTXA(R), Myobloc(R) and NeuroBloc(R), have been used with great ..
  7. HEPylated G-CSF: Drug with Safer, Enhanced Delivery for Neutropenia Treatment
    Wei Jing; Fiscal Year: 2011
    ..that are potentially being undermined by a plethora of PEG- containing consumer products including toothpaste, cosmetics, processed foods, and laxatives such that ~22-25% of the US population in 2001 (up from 0...
  8. eukaryotic expression vectors resistant to transgene silencing
    James Williams; Fiscal Year: 2012
    ..In Phase III the gene therapies for diabetic foot ulcers and skin cosmetics will undergo clinical development...
  9. Ear Canal Optical Coherent Tomography System
    PAUL SHNITSER; Fiscal Year: 2010
    ..hearing aid candidates actually use these devices, owing to concerns about inconvenience, discomfort, stigma, cosmetics, sound quality, and affordability...
  10. A rapid label-free sensor for immune markers of environmental exposure for applic
    Christopher Striemer; Fiscal Year: 2012
    ..The explosive growth of nanotechnology in research and consumer products (sunscreens, cosmetics, paint) is also creating an array of ultrafine materials with largely unknown health effects...
  11. Molecular Mechanisms of Obesity in Children Exposed to Phthalates in Utero
    Nina T Holland; Fiscal Year: 2013
    ..Evidence from animals and epidemiologic studies suggests that phthalates, components of plastics and cosmetics ubiquitously found in humans, may be obesogenic...
  12. XENOBIOTICS AND PRIMARY BILIARY CIRRHOSIS
    MERRILL E GERSHWIN; Fiscal Year: 2013
    ..on our functional data that autoimmune cholangitis can be induced by immunization of 2OA, a material found in cosmetics. In particular, we will define the role of effector mechanisms in this model that allows dissection of early ..
  13. Immunostimulatory properties of chitin and chitosan
    CHARLES ALLEN SPECHT; Fiscal Year: 2012
    ..Chitin and/or chitosan are used in cosmetics and biomaterials, have been postulated to play a role in asthma, and have been proposed as vaccine adjuvants...
  14. Cytoxic and Genotoxic Effects of Manufactured Nanoparticles on Stem Cells
    Yiling Hong; Fiscal Year: 2011
    ..that are, or will be, prominently used in commercially available products: carbon NPs (car wax, fuel lines, cosmetics), silver NPs (antimicrobial wound dressings, odor-reducing socks), titanium dioxide NPs (sunscreens, paints), ..
  15. NITRIC OXIDE INHIBITOR AND LEISHMANIA PATHOGENESIS
    MARION CHAN; Fiscal Year: 2004
    ..Rural populations in India use turmeric abundantly in their daily life: as a spice, as a component of cosmetics, as an anti-inflammatory agent and other medications, and as a household topical remedy for minor injuries ..
  16. Impact of Environmental Pollutants on Breast Cancer and*
    Julia Brody; Fiscal Year: 2005
    ..to EDCs and mammary carcinogens is common from sources such as air and water pollution, detergents, pesticides, cosmetics, plastics, building materials, and furnishings...
  17. NITRIC OXIDE INHIBITOR AND LEISHMANIA PATHOGENESIS
    MARION CHAN; Fiscal Year: 2000
    ..Rural populations in India use turmeric abundantly in their daily life: as a spice, as a component of cosmetics, as an anti-inflammatory agent and other medications, and as a household topical remedy for minor injuries ..
  18. Enhanced Phototoxicity Assay in Reconstituted Skin
    GEORGE DEGEORGE; Fiscal Year: 2002
    ..The phototoxic potential of chemicals, cosmetics, dietary supplements and pharmaceuticals are a growing major concern in the consumer products industry...
  19. RIBONUCLEOSIDES FOR PREDICTION OF SKIN IRRITATION
    WILLIAM REIFENRATH; Fiscal Year: 1999
    ..PROPOSED COMMERCIAL APPLICATION Development of new materials that contact the skin (e.g. topical drugs, cosmetics) usually requires an assessment of skin irritation potential in an animal model...
  20. Nursing & Environmental Health Conference: Methymercury and Human Health Effects
    Jeanne Hewitt; Fiscal Year: 2006
    ..communication by Hmong; a poster presentation session that illustrates traditional medicines, herbs, candies, cosmetics, and other products that can be sources of exposure to mercury, lead, and other toxins; a science experiment ..
  21. Tooth Phone Auditory Device TPAD
    BARRY MERSKY; Fiscal Year: 2009
    ..to the precedent device, the TPAD has many important advantages such as cost, safety, longevity, fidelity, and cosmetics. In the TPAD system, ambient speech and sound is picked-up by a microphone and radio transmitted to a removable ..
  22. MINORITY PREDOCTORAL FELLOWSHIP PROGRAM
    SHONDELLE WILSON; Fiscal Year: 2004
    ..photo-oxidation of methane, oxidation of hydrocarbons released from plants and by numerous industrial products (cosmetics, cigarette smoke, automotive emissions, etc.); that contain this chemical as an ingredient...
  23. Phototoxicity Screening Assay in Reconstituted Skin
    GEORGE DEGEORGE; Fiscal Year: 2006
    ..The phototoxic potential of chemicals, cosmetics, dietary supplements and Pharmaceuticals are a major and growing concern in the consumer products industry, but ..
  24. Mechanism of Thimerosal Induced Neurotoxicity
    KINSLEY KININGHAM; Fiscal Year: 2003
    ..is a widely used ethyl mercury containing preservative used in over-the-counter medications, cleaners and cosmetics. Recent concern has been raised on the use of thimerosal in over 30 vaccines licensed in the United States...
  25. Nanoparticles and Arterial Disease
    VIRGINIA MILLER; Fiscal Year: 2009
    ..Nanoparticles are being developed for such diverse industrial applications as data processing and cosmetics, and in medicine for targeted drug delivery, surface coatings to improve implantable devices and biosensors...
  26. NOVEL OLIGOPEPTIDES AS TOPICAL SKIN LIGHTENING AGENTS
    JAMES LEYDA; Fiscal Year: 2001
    ..Additionally, the desire for skin whitening cosmetics is common in various cultures around the world...
  27. Neurotoxic Interactions of Different Forms of Mercury
    Bernard Weiss; Fiscal Year: 2007
    ..health risks are methylmercury, found in fish and marine mammals, and metallic mercury vapor, found in industry, cosmetics, and dental amalgams...
  28. Diethanolamine, brain development and adult memory
    Steven Zeisel; Fiscal Year: 2006
    ..in the synthesis of fatty acid condensates that are present in many consumer products, including shampoos and cosmetics. DEA is structurally similar to choline, a methyl donor and an important endogenous precursor in the synthesis ..
  29. An In Vitro Robotic Assay for Anti-Estrogenic Activity
    CATHY YANG; Fiscal Year: 2006
    ..Recent scientific investigations have shown that many chemicals used in plastics, Pharmaceuticals, pesticides, cosmetics, food additives, etc., are endocrine disrupters (EDs)...
  30. In Vitro Robotic Assay for Estrogenic Activity
    CATHY YANG; Fiscal Year: 2005
    Recent scientific investigations have shown that many chemicals used in plastics, pharmaceuticals, )esticides, cosmetics, food additives, etc. are endocrine disruptors (EDs)...
  31. An In Vitro Robotic Assay for Estrogenic Activity
    CATHY YANG; Fiscal Year: 2002
    Recent scientific investigations have shown that many chemicals used in plastics, pharmaceuticals, pesticides, cosmetics, food additives, etc...
  32. BRAIN TUMORS AND N-NITROSO EXPOSURES
    Baruch Modan; Fiscal Year: 1992
    ..The questionnaire asks about sources of NOC exposure such as diet, drugs, cosmetics, rubber products and parental occupational exposures...
  33. BIOSTATISTICAL METHODS FOR CARCINOGENICITY EXPERIMENTS
    Stephen Lagakos; Fiscal Year: 1990
    ..problems arising in laboratory experiments designed to assess the potential hazards of food additives, drugs, cosmetics, and other chemicals...
  34. Development of a New High-Throughout Mammalian DEL Assay
    Richard Brennan; Fiscal Year: 2001
    ..by applicant) Molecular toxicology is playing an increasing role in the early development of pharmaceuticals, cosmetics, chemicals, and food additives...
  35. A Catalytic Conformational Prion Sensor
    Cindy Orser; Fiscal Year: 2002
    ..PROPOSED COMMERCIAL APPLICATION: Beef and beef-by-products are omnipresent in foods, drugs, vaccines, and cosmetics, and the subclinical presence of an undiagnosed epidemic of transmissible spongiform encephalopathy (TSE) could ..
  36. BARRIER FUNCTION IN NORMAL IMMORTALIZED KERATINOCYTE
    ALLEN COMER; Fiscal Year: 2001
    ..Such tests are needed to prevent the inclusion of ingredients in consumer products, cosmetics or topically applied pharmaceuticals that would damage this critical function of skin...
  37. Reporter gene assays for skin irritation assessment
    ALLEN COMER; Fiscal Year: 2001
    ..Such tests are needed to prevent the inclusion of irritating ingredients in consumer products, cosmetics, or topically applied pharmaceuticals...
  38. BIOSENSOR STUDIES OF ESTROGENIC COMPOUNDS WITH HER-A & B
    JUDITH ERB; Fiscal Year: 2002
    ..Also diethyl phthalate, a compound widely used in colognes and cosmetics, selectively activates formation of stable complex between ERE and hER-alpha but not hER-beta...
  39. ARRAYS FOR BINAURAL ADAPTIVE DIRECTIONAL HEARING AID
    Scott Shaw; Fiscal Year: 2000
    ..PROPOSED COMMERCIAL APPLICATION: The primary commercial application of the research is to improve both the cosmetics and the speech-in-noise performance of directional hearing devices, such as hearing aids or cochlear implants...
  40. Investigation of a Behavioral Substitute for Sunbathing
    Sherry Pagoto; Fiscal Year: 2007
    ..Prevention interventions that target high-risk segments of the community in settings where risk behavior occurs have potential for a large and focused public health impact. [unreadable] [unreadable] [unreadable]..
  41. Guided Pocket Recolonization (GPR) in Periodontitis
    Marc Quirynen; Fiscal Year: 2004
    ..Clinical data will be collected after 2, 4, 6, 8 and 12 weeks. The results should indicate the possible role for commensal organisms in periodontal disease and subgingival biofilm formation. ..
  42. Obesity and Negative Affect-Induced Eating
    Sherry Pagoto; Fiscal Year: 2007
    ..The University of Illinois at Chicago provides an ideal setting for training behavioral scientists and the mentoring team will provide a sound training experience for the PI from which an academic career can be launched. ..
  43. NNK, Beta-Adrenergic AA Release and Lung Cancer
    HILDEGARD SCHULLER; Fiscal Year: 2005
    ..2. To determine which products of the AA cascade are formed in untreated cells and in response to NNK, which of these products stimulate DNA synthesis, and what downstream effectors are activated by these products. ..
  44. Immortized Human Langerhans Cells
    Seyoum Ayehunie; Fiscal Year: 2002
    ..Finally, a skin model containing immunologically competent cells would be extremely valuable to a large number of companies in evaluating whether their products are likely to cause allergic contact dermatitis...
  45. In Vitro Tissue Model of Psoriasis
    Seyoum Ayehunie; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  46. Human Corneal Model for Ocular Irritation Assay
    Yulia Kaluzhny; Fiscal Year: 2008
    ..We will develop a corneal full thickness tissue and in vitro test methods that will dramatically reduce or eliminate the need to use animals to assess ocular irritancy of chemicals and products. [unreadable] [unreadable] [unreadable]..
  47. Tools for Targeted Delivery of DNA into Mammalian Cells
    ALEXEY ZDANOVSKY; Fiscal Year: 2004
    ..coil into mammalian cells. Also, we expect to lay a foundation for construction of customized bacteriophage-based DNA delivery systems suitable for genetic therapy applications. ..
  48. PROTEASE INHIBITOR-INDUCED HYPERLIPIDEMIA IN AIDS
    Virgil Brown; Fiscal Year: 2004
    ..These are specific agents that are effective in reducing triglyceride as well as improving insulin resistance. ..
  49. Approach for amplification of molecular signals
    ALEXEY ZDANOVSKY; Fiscal Year: 2005
    ..Bacterial luciferase will be incorporated in the naturally existing cascades of enzymatic reactions to produce an inexpensive and simple assay for the detection of antigens of interest including those of biowarfare agents. ..
  50. Biological Analysis of Toxic DEP Chemicals
    Andre Nel; Fiscal Year: 2006
    ..We will determine if inhaled ambient PM induce apoptosis in induced sputum samples in humans. ..
  51. Tanning bed use among UI Students
    Leslie Dennis; Fiscal Year: 2003
    ..abstract_text> ..
  52. Community Based Clinical Trials Education Program
    Georgia Sadler; Fiscal Year: 2006
    ..The clinical trials. infrastructure has had extensive revisions to allow for accurate endpoint assessment with future efforts. ..
  53. Proteomics of DEP-induced Oxidative Stress
    Andre Nel; Fiscal Year: 2006
    ..They will also use a display of protein carbonyls to identity oxidatively modified proteins in the BAL fluid. ..
  54. Pre-validation of Tissue Specific Micronucleus Assay for Genotoxicity Testing
    Yulia Kaluzhny; Fiscal Year: 2006
    ..are also used; however, beginning in 2009, legislation in Europe will prevent manufacturers from marketing cosmetics products that have been tested using animals...
  55. Probes and cell arrays for detection of bacterial toxins
    ALEXEY ZDANOVSKY; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  56. Infection, Persistence & Clearance of Oral HPV in Women
    Jimmy Efird; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  57. Atherogenic Effects of Ambient PM In Susceptible Animals
    Andre Nel; Fiscal Year: 2007
    ..These mice will be exposed to CAPs as discussed in Aims 1 and 2, and select endpoints used to demonstrate the effect on atherosclerotic inflammation and apoptosis. ..
  58. Validation of Organotypic Vaginal Tissue Based Assay for Endocrine Disruptors
    Seyoum Ayehunie; Fiscal Year: 2007
    ..The proposed human organotypic tissue based assay will provide a sensitive and specific assay method to screen a large number of endocrine disrupting chemicals at a reduced cost. [unreadable] [unreadable] [unreadable]..
  59. Preclin. model for prevention of NSCLC in former smokers
    HILDEGARD SCHULLER; Fiscal Year: 2006
    ....
  60. Development of methods and models for nanoparticle toxicity screening: Applicatio
    Andre Nel; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  61. LIPID METABOLISM IN HUMAN KERATINOCYTES
    KATHI MADISON; Fiscal Year: 2004
    ..Ultimately, these studies will contribute to fundamental knowledge about the regulation of epidermal differentiation at the molecular level. ..