emollients

Summary

Summary: Oleagenous substances used topically to soothe, soften or protect skin or mucous membranes. They are used also as vehicles for other dermatologic agents.

Top Publications

  1. ncbi Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders
    Marie Lodén
    ACO HUD AB, Stockholm, Sweden
    Am J Clin Dermatol 4:771-88. 2003
  2. ncbi Promoting skin health
    Sara Burr
    Nurs Stand 19:57-65; quiz 66. 2005
  3. ncbi It's a wrap: the use of wet pajamas in wet-wrap dressings for atopic dermatitis
    Kelly L Barham
    Wake Forest University School of Medicine, Winston Salem, NC, USA
    Dermatol Nurs 17:365-7. 2005
  4. ncbi Emollients: application of topical treatments to the skin
    Gail Dunning
    York Hospital Foundation Trust
    Br J Nurs 16:1342-5. 2007
  5. ncbi [Do emollients prevent active episodes of atopic dermatitis?]
    K Khadir
    Ann Dermatol Venereol 135:139-40. 2008
  6. ncbi A review of the pathophysiology, prevention and treatment of irritant diaper dermatitis
    David J Atherton
    Department of Paediatric Dermatology, Great Ormond Street Hospital for Children, London WC1N 3JH, UK
    Curr Med Res Opin 20:645-9. 2004
  7. ncbi Changes in skin barrier function following long-term treatment with moisturizers, a randomized controlled trial
    I Buraczewska
    Department of Medical Sciences, Dermatology and Venereology, University Hospital, Uppsala, Sweden
    Br J Dermatol 156:492-8. 2007
  8. doi Questionnaire survey of the efficacy of emollients for adult patients with atopic dermatitis
    Tamihiro Kawakami
    Department of Dermatology, St Marianna University School of Medicine, Kawasaki, Japan
    J Dermatol 38:531-5. 2011
  9. pmc Cost-effectiveness of skin-barrier-enhancing emollients among preterm infants in Bangladesh
    Amnesty Lefevre
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States of America
    Bull World Health Organ 88:104-12. 2010
  10. ncbi Practical issues for emollient therapy in dry and itchy skin
    Sandra Lawton
    Dermatology Department, Queen s Medical Centre, Nottingham University, Hospitals NHS Trust, Nottingham
    Br J Nurs 18:978-84. 2009

Detail Information

Publications216 found, 100 shown here

  1. ncbi Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders
    Marie Lodén
    ACO HUD AB, Stockholm, Sweden
    Am J Clin Dermatol 4:771-88. 2003
    b>Emollients and moisturizing creams are used to break the dry skin cycle and to maintain the smoothness of the skin...
  2. ncbi Promoting skin health
    Sara Burr
    Nurs Stand 19:57-65; quiz 66. 2005
    ..It discusses the key structures of the skin and its functions, the role of emollient therapy in children and adults, and external environmental factors...
  3. ncbi It's a wrap: the use of wet pajamas in wet-wrap dressings for atopic dermatitis
    Kelly L Barham
    Wake Forest University School of Medicine, Winston Salem, NC, USA
    Dermatol Nurs 17:365-7. 2005
  4. ncbi Emollients: application of topical treatments to the skin
    Gail Dunning
    York Hospital Foundation Trust
    Br J Nurs 16:1342-5. 2007
    ..b>Emollients have an as important part to play in the treatment of all dry skin conditions...
  5. ncbi [Do emollients prevent active episodes of atopic dermatitis?]
    K Khadir
    Ann Dermatol Venereol 135:139-40. 2008
  6. ncbi A review of the pathophysiology, prevention and treatment of irritant diaper dermatitis
    David J Atherton
    Department of Paediatric Dermatology, Great Ormond Street Hospital for Children, London WC1N 3JH, UK
    Curr Med Res Opin 20:645-9. 2004
    ..In this review, the pathophysiology of IDD is outlined and its prevention and treatment are discussed, with particular reference to the role of emollients.
  7. ncbi Changes in skin barrier function following long-term treatment with moisturizers, a randomized controlled trial
    I Buraczewska
    Department of Medical Sciences, Dermatology and Venereology, University Hospital, Uppsala, Sweden
    Br J Dermatol 156:492-8. 2007
    ..However, knowledge of the effects on skin barrier function of long-term treatment with moisturizers is still scarce...
  8. doi Questionnaire survey of the efficacy of emollients for adult patients with atopic dermatitis
    Tamihiro Kawakami
    Department of Dermatology, St Marianna University School of Medicine, Kawasaki, Japan
    J Dermatol 38:531-5. 2011
    b>Emollients are useful and important treatment adjuncts for patients with atopic dermatitis (AD). Heparinoid mucopolysaccharide creams or lotions are emulsion ointments for moisturizing the skin...
  9. pmc Cost-effectiveness of skin-barrier-enhancing emollients among preterm infants in Bangladesh
    Amnesty Lefevre
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States of America
    Bull World Health Organ 88:104-12. 2010
    To evaluate the cost-effectiveness of topical emollients, sunflower seed oil (SSO) and synthetic Aquaphor, versus no treatment, in preventing mortality among hospitalized preterm infants (< 33 weeks gestation) at a tertiary hospital in ..
  10. ncbi Practical issues for emollient therapy in dry and itchy skin
    Sandra Lawton
    Dermatology Department, Queen s Medical Centre, Nottingham University, Hospitals NHS Trust, Nottingham
    Br J Nurs 18:978-84. 2009
    ..This will restore the skin barrier function, reduce itch and suit the patient...
  11. ncbi The vital role of emollients in the treatment of eczema
    David Voegeli
    Continence Technology and Skin Health Group, Faculty of Health Sciences, University of Southampton
    Br J Nurs 20:74-80. 2011
    Eczema is one of the most common dermatological diseases, with the number of cases in the UK rising. The use of emollients to maintain skin hydration and help restore barrier function, remains the principal treatment...
  12. doi Evaluation of the moisturizer Pédimed(®) in the foot care of diabetic patients
    E Garrigue
    Institut de Recherche Pierre Fabre, CRDPF Toulouse Langlade, 3, avenue Hubert Curien, 31035 Toulouse cedex 1, France
    Diabetes Metab 37:330-5. 2011
    ..Its treatment is therefore paramount and must be implemented early on. The objective of this study was to assess the moisturizing properties of Pédimed(®) cream in the treatment of foot xerosis in diabetic patients...
  13. ncbi Using emollients to restore and maintain skin integrity
    Philip Watkins
    Sutton and Merton Primary Care Trust, Mitcham, Surrey
    Nurs Stand 22:51-7; quiz 58. 2008
    b>Emollients are an essential treatment option for the reduction of dry skin conditions and the maintenance of healthy skin...
  14. ncbi Xerosis of the feet: a comparative study on the effectiveness of two moisturizers
    Paul Baalham
    Br J Community Nurs 16:591-2, 594-7. 2011
    ..Results showed that the regular use of both moisturizers had a significant hydrating effect on the skin. However, CCS Foot Care Cream had a significantly greater hydrating effect than Aqueous Cream BP...
  15. doi Emollients, education and quality of life: the RCPCH care pathway for children with eczema
    Helen Cox
    Department of Paediatrics, Imperial College Healthcare Trust, London SW7 2AZ, UK
    Arch Dis Child 96:i19-24. 2011
    ..The eczema pathway focuses on defining the competences to improve the equity of care received by children with eczema...
  16. doi Skin care in the NICU patient: effects of wipes versus cloth and water on stratum corneum integrity
    Marty Visscher
    Skin Sciences Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Neonatology 96:226-34. 2009
    ..There is a need to minimize damage, facilitate skin development and reduce infection risk, but the literature on the effects of skin care practices in NICU patients is limited...
  17. ncbi The use of emollient therapy for ageing skin
    P Watkins
    Epsom and St Helier University Hospitals NHS Trust, Surrey
    Nurs Older People 23:31-7. 2011
    ..Better understanding of skin ageing and the usefulness of emollients can be reinforced by education and encouragement from healthcare professionals...
  18. ncbi Advised best practice for the use of emollients in eczema and other dry skin conditions
    C Holden
    St Helier Hospital, Carshalton, Surrey, UK
    J Dermatolog Treat 13:103-6. 2002
    ..One area that could benefit greatly from increased patient education and participation is the use of emollients. Emollients are frequently prescribed for patients with eczema and other dry skin conditions...
  19. ncbi Emollients in a propanol-based hand rub can significantly decrease irritant contact dermatitis
    Gunter Kampf
    Bode Chemie GmbH and Co, Scientific Affairs, Melanchthonstr 27, 22525 Hamburg, Germany
    Contact Dermatitis 53:344-9. 2005
    The objective of this study is to determine the effect of emollients in a propanol-based hand rub on skin dryness and erythema...
  20. ncbi Comparison of parent knowledge, therapy utilization and severity of atopic eczema before and after explanation and demonstration of topical therapies by a specialist dermatology nurse
    M J Cork
    Paediatric Dermatology Clinic, Sheffield Children s Hospital, Sheffield S10 2TH, UK
    Br J Dermatol 149:582-9. 2003
    ..There has been little work assessing compliance/concordance with complex treatment regimens for atopic eczema. Asthma schools led by specialist nurses have been shown to improve knowledge, use of therapies and clinical outcome...
  21. ncbi Evidence-based skin care management in radiation therapy
    Maurene McQuestion
    Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario, Canada
    Semin Oncol Nurs 22:163-73. 2006
    ..To review published studies evaluating interventions for the prevention and management of radiation skin reactions/dermatitis...
  22. doi The role of emollients in the management of diseases with chronic dry skin
    E Proksch
    Department of Dermatology, University of Kiel, Kiel, Germany
    Skin Pharmacol Physiol 21:75-80. 2008
    ..Within the overall treatment regimen for these diseases, the use of emollients to manage dry skin plays a considerable role in managing skin conditions...
  23. ncbi Gentamicin ointment versus petrolatum for management of auricular wounds
    Ross M Campbell
    Department of Dermatology, Brown Medical School, Providence, Rhode Island, USA
    Dermatol Surg 31:664-9. 2005
    ..Potentially significant complications of second-intention healing on the ear are suppurative and inflammatory chondritis. Consequently, many physicians advocate the use of oral or topical prophylactic antibiotics after auricular surgery...
  24. doi Emollients, moisturizers, and keratolytic agents in psoriasis
    Joachim W Fluhr
    Bioskin, Seydelstr 18, D 10117 Berlin, Germany
    Clin Dermatol 26:380-6. 2008
    b>Emollients, moisturizers, and keratolytic agents are essential in the topical treatment of psoriasis. They are adjuvants for classic treatments and help to reduce the scale load of individual patients...
  25. ncbi A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema
    M Pitt
    Peninsula Technology Assessment Group, Peninsula Medical School, Dean Clarke House, Southernhay East, Exeter EX1 1PQ, U K
    Br J Dermatol 154:1137-46. 2006
    Conventional treatments for atopic eczema include topical corticosteroids (TCS) and emollients. Pimecrolimus, an immunosuppressant, was licensed in the U.K. in 2003 as an alternative treatment of mild to moderate atopic eczema.
  26. ncbi Dermal tolerance of Sterillium, a propanol-based hand rub
    G Kampf
    Bode Chemie GmbH and Co, Scientific Affairs, Melanchthonstrasse 27, 22525 Hamburg, Germany
    J Hosp Infect 55:295-8. 2003
    ..potential for dermal irritation and sensitization of commercially available propanol-based hand rubs containing emollients has not been studied systematically...
  27. ncbi Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea
    Zoe Diana Draelos
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Cutis 76:135-41. 2005
    ..Instruments provided objective measures of stratum corneum barrier function and hydration on the face...
  28. doi Measuring the effects of topical moisturizers on changes in stratum corneum thickness, water gradients and hydration in vivo
    J M Crowther
    Procter and Gamble Technical Centres Ltd, Rusham Park, Whitehall Lane, Egham, Surrey, TW20 9NW, UK
    Br J Dermatol 159:567-77. 2008
    ....
  29. ncbi Effect of topical treatment with skin barrier-enhancing emollients on nosocomial infections in preterm infants in Bangladesh: a randomised controlled trial
    Gary L Darmstadt
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Lancet 365:1039-45. 2005
    ..Our aim was to ascertain whether topical application of emollients to enhance skin barrier function would prevent nosocomial infections in this population.
  30. ncbi Emollients and the response of facial skin to a cold environment
    A Thorleifsson
    Department of Dermatology D92, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark
    Br J Dermatol 148:1149-52. 2003
    It is debated whether the use of emollients, in cold weather, constitutes a protective factor or a risk factor for frostbite.
  31. ncbi Treatment of patients with atopic dermatitis using wet-wrap dressings with diluted steroids and/or emollients. An expert panel's opinion and review of the literature
    A P Oranje
    Department of Dermatology and Venereology, Erasmus MC, Rotterdam, The Netherlands
    J Eur Acad Dermatol Venereol 20:1277-86. 2006
    ....
  32. pmc Moisturizing body milk as a reservoir of Burkholderia cepacia: outbreak of nosocomial infection in a multidisciplinary intensive care unit
    Francisco Alvarez-Lerma
    Service of Intensive Care Medicine, Hospital Universitari del Mar, Universitat Autonoma de Barcelona, Passeig Maritim 25 29, E 08003 Barcelona, Spain
    Crit Care 12:R10. 2008
    ..An outbreak of severe nosocomial Burkholderia cepacia infections in patients admitted to intensive care unit (ICU), including investigation of the reservoir, is described...
  33. ncbi Improvement in skin barrier function in patients with atopic dermatitis after treatment with a moisturizing cream (Canoderm)
    M Loden
    Research and Development, ACO HUD AB, Box 542, S 18215 Danderyd, Stockholm, Sweden
    Br J Dermatol 140:264-7. 1999
    ..05). Thus, it seems that certain moisturizers could improve skin barrier function in atopics and reduce skin susceptibility to irritants. The mechanism and the clinical relevance need further investigation...
  34. ncbi Tretinoin cream 0.02% for the treatment of photodamaged facial skin: a review of 2 double-blind clinical studies
    J Nyirady
    Johnson and Johnson Consumer Products Worldwide, Skillman, New Jersey 08558-9418, USA
    Cutis 68:135-42. 2001
    ..02% was well tolerated overall and demonstrated a favorable safety profile. Both studies demonstrated that tretinoin cream 0.02% is safe and effective for the treatment of moderate-to-severe photodamaged facial skin...
  35. ncbi Facilitating facial retinization through barrier improvement
    Zoe Diana Draelos
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Cutis 78:275-81. 2006
    ....
  36. doi Emollients improve treatment results with topical corticosteroids in childhood atopic dermatitis: a randomized comparative study
    Jolanta Szczepanowska
    Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland
    Pediatr Allergy Immunol 19:614-8. 2008
    The aim of the study was to investigate whether adding emollients to the standard topical corticosteroid therapy influences the outcome of children with atopic dermatitis...
  37. ncbi Does hand care ruin hand disinfection?
    P Heeg
    Department of Hospital Infection Control, Tuebingen University Hospitals, Eberhard Karls University, Germany
    J Hosp Infect 48:S37-9. 2001
    ..Our data suggest that administration of selected products for hand care does not necessarily impair hand disinfection and is therefore recommended for occupational health as well as for infection control reasons...
  38. ncbi Evaluation of barrier creams against sulphur mustard: (II) In vivo and in vitro studies using the domestic white pig
    Robert P Chilcott
    Chemical Hazards and Poisons Division, Health Protection Agency, Chilton, Didcot, Oxfordshire, United Kingdom
    Cutan Ocul Toxicol 26:235-47. 2007
    ..cm(-2), respectively), further validating the use of pigs as a toxicologically-relevant dermal model for SM exposure...
  39. ncbi Patchy eczema of elderly patients
    William D James
    Cutis 80:18. 2007
  40. ncbi Fluorescent silica colloids for study and visualization of skin care products
    Swaminathan Iyer
    Department of Physics, Clarkson University, Potsdam, NY 13699 5820, USA
    Skin Res Technol 13:317-22. 2007
    ..Here, we describe a novel method based on non-contact optical measurements to trace the location and dynamics of skin care products on the skin...
  41. ncbi Skin care in the well term newborn: two systematic reviews
    Lynne Walker
    Fylde and Wyre National Health Service Hospital Trust, Blackpool, England
    Birth 32:224-8. 2005
    ..use of soaps or detergents in bath water is associated with the development of dry, cracked, or flaking skin in the perinatal period, and short- and long-term consequences of the use of emollients, lotions, or moisturizers for dry skin.
  42. ncbi Skin barrier function and the use of emollients in dermatological nursing
    Sandra Lawton
    Queen s Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK
    Br J Nurs 16:712, 714, 716, 718-9. 2007
    ..This article explores the barrier function of the skin, factors which influence skin barrier function and the use of emollients for dry skin and skin conditions.
  43. ncbi Placebo-controlled, double-blind, randomized, prospective study of a glycerol-based emollient on eczematous skin in atopic dermatitis: biophysical and clinical evaluation
    M Breternitz
    Skin Physiology Laboratory, Department of Dermatology, Friedrich Schiller University, Jena, Germany
    Skin Pharmacol Physiol 21:39-45. 2008
    ..The therapeutic management of AD is difficult and needs individualized concepts. Moisturizing creams and emollients are useful and important treatment adjuncts for the daily skin care of patients with dry and inflamed skin, e.g...
  44. ncbi Recommendation of moisturizers and cleansers: a study of unmet needs among dermatology patients
    Diane Berson
    New York Presbyterian Hospital, New York, NY, USA
    Cutis 76:3-6. 2005
    ..In addition, it was found that overall patient satisfaction with the care received from their dermatologist is driven by communication...
  45. ncbi Protocol to predict the dry skin benefit from the unique in-shower body lotion product form
    Keith Ertel
    The Procter and Gamble Company, Sharon Woods Innovation Center, Cincinnati, OH 45241, USA
    J Cosmet Sci 59:253-62. 2008
    ..The resulting protocol is consumer-relevant, and reliably and reproducibly predicts dry skin improvement from the in-shower body lotion product form...
  46. ncbi Exploring the use of emollient therapy in dermatological nursing
    Jill Peters
    Ipswich Primary Care Trust
    Br J Nurs 14:494-502. 2005
    ..This is done through education, negotiation and trial of emollients. Health practitioners should ensure that patients understand how the environment challenges the skin, the ..
  47. ncbi Lipophilic and hydrophilic moisturizers show different actions on human skin as revealed by cryo scanning electron microscopy
    Julia Caussin
    Gorlaeus Laboratories, Leiden Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Exp Dermatol 16:891-8. 2007
    ..Summarizing, SC cells are not equally sensitive to moisturizer application: centrally located corneocytes are more sensitive than corneocytes in the upper and the lowest regions of the SC...
  48. ncbi Clinical practice. Atopic dermatitis
    Hywel C Williams
    Center of Evidence Based Dermatology, Queen s Medical Center, University of Nottingham, Nottingham, United Kingdom
    N Engl J Med 352:2314-24. 2005
  49. ncbi Atopic eczema: nurse-led care--2. Treatments
    Sandra Lawton
    Queen s Medical Centre, University Hospital, Nottingham
    J Fam Health Care 15:51-4. 2005
    ..The principles of selecting and using emollients and the use of topical corticosteroids are also discussed...
  50. ncbi Moisturizers: what they are and a practical approach to product selection
    J N Kraft
    Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Skin Therapy Lett 10:1-8. 2005
    ..They contain varying combinations of emollients, occlusives, and humectants to achieve their beneficial effects, and there is an overwhelming number of ..
  51. pmc Acceptability of massage with skin barrier-enhancing emollients in young neonates in Bangladesh
    A S M Nawshad Uddin Ahmed
    Department of Neonatology, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka, Bangladesh
    J Health Popul Nutr 25:236-40. 2007
    ..study was carried out to gain insights into oil-massage practices and acceptability of skin barrier-enhancing emollients in young, preterm Bangladeshi neonates...
  52. ncbi The clinical benefit of moisturizers
    M Loden
    ACO HUD AB, Stockholm, Sweden
    J Eur Acad Dermatol Venereol 19:672-88; quiz 686-7. 2005
    ..Patients and the society expect dermatologists and pharmacists to be able to recommend treatment for various dry skin conditions upon evidence-based medicine...
  53. ncbi Functional assessment of a skin care system in patients on chemotherapy
    J W Fluhr
    Skin Physiology Laboratory, Friedrich Schiller University, Jena, Germany
    Skin Pharmacol Physiol 20:253-9. 2007
    ..The aim of this study was to verify whether a concomitant treatment with an acidic washing and an acidic emollient (both pH 5.5) can significantly improve the quality of the skin in such patients...
  54. ncbi Use of moisturizers in dermatologic disease: the role of healthcare providers in optimizing treatment outcomes
    Noreen Heer Nicol
    National Jewish Medical and Research Center, University of Colorado, Denver, USA
    Cutis 76:26-31. 2005
    ..In addition to topical moisturizers, medications, wet wraps, and hydration therapy has become a frequently used practice in the management of atopic dermatitis...
  55. ncbi Concepts in skin care maintenance
    Zoe Diana Draelos
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Cutis 76:19-25. 2005
    ....
  56. ncbi The effect of ceramide-containing skin care products on eczema resolution duration
    Zoe Diana Draelos
    Dermatology Consulting Services, High Point, North Carolina, USA
    Cutis 81:87-91. 2008
    ..Thus, skin care product selection can have an important clinical effect on the clearance of mild to moderate eczema...
  57. doi Protection effect of cosmetics on human skin under simulated rigorous environment
    Yan Cheng
    Beijing Sino German Union Cosmetic Institute Co, Chinese Academy of Inspection and Quarantine, Beijing, China
    Skin Res Technol 14:45-52. 2008
    ..The aim of this study was to develop a model for the evaluation of the efficacy of cosmetics on human skin under simulated rigorous environment...
  58. ncbi Impaired skin barrier function in dermatologic disease and repair with moisturization
    Mark Lebwohl
    Department of Dermatology, Mount Sinai School of Medicine, New York, New York, USA
    Cutis 76:7-12. 2005
    ..Some emollients also supply the compromised stratum corneum with vital lipids and accelerate barrier recovery...
  59. ncbi [Indications for sunflower oil concentrate in the treatment of atopic dermatitis]
    Gerardo López Pérez
    Alergólogo infectólogo pediatra, Servicio de alergia del Instituto Nacional de Pediatria, Mexico, D F
    Rev Alerg Mex 53:217-25. 2006
    ..This article includes a series of concepts that justify the use of sunflower oil concentrated like a weapon of forward edge in the treatment of these morbidities...
  60. ncbi Moisturizers
    Jasna Lipozencic
    University Department of Dermatology and Venereology, Zagreb University Hospital Center, Salata 4 HR 10000 Zagreb, Croatia
    Acta Dermatovenerol Croat 14:104-8. 2006
    ..These agents mimic natural ingredients. Application of moisturizers can serve as important adjunctive therapy for patients with various dermatologic disorders...
  61. ncbi Understanding psoriasis and the treatment options
    Jane Freak
    Wessex Cancer Trust MARC s Line, Dermatology, Salisbury District Hospital
    Nurs Times 102:47, 49. 2006
  62. ncbi Clobetasol propionate for psoriasis: are ointments really more potent?
    Lindsey Warino
    Ohio State University College of Medicine, School of Public Health, Columbus, OH, USA
    J Drugs Dermatol 5:527-32. 2006
    ..We excluded studies conducted before 1980 and those that allowed concomitant treatments...
  63. ncbi The effect of bilayer and hexagonal H(II) phase lipid films on transepidermal water loss
    Sameersingh G Raney
    University of British Columbia, Vancouver, BC, Canada
    Exp Dermatol 15:493-500. 2006
    ..This results in the formation of a durable surface barrier capable of significantly reducing TEWL from damaged skin...
  64. ncbi An overview of atopic eczema in children: a significant disease
    Steve Gill
    Birmingham Children s Hospital
    Br J Nurs 15:494-9. 2006
    ..This often breaks down and becomes infected, partly as a result of the close relationship of atopic eczema and the organism Staphylococcus aureus, which is found on the skin of most children with atopic eczema (Goodyear, 1993)...
  65. ncbi Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams
    B Bocca
    Istituto Superiore di Sanita, Department of Environment and Primary Prevention, Viale Regina Elena 299, 00161 Rome, Italy
    J Pharm Biomed Anal 44:1197-202. 2007
    ..Nevertheless, some creams presented amounts of Co and Cr comparable to those of Ni and therefore they have to be monitored in consideration of their cross-reactivity as well...
  66. ncbi Avoiding allergic contact dermatitis in patients with venous leg ulcers
    Pauline Beldon
    Epsom and St Helier University Hospital, NHS Trust, Surrey, UK
    Br J Community Nurs 11:S6, S8, S10-2. 2006
    ..This article explores how the practitioner can recognize allergic contact dermatitis in a patient with a venous leg ulcer and avoid the use of avoid potential skin sensitizers during management...
  67. ncbi Increased susceptibility to Staphylococcus aureus colonization of the skin of the NOA mouse: a potentially useful animal model for evaluating antiseptic effects
    Taizo Kondo
    Division of Pharmacology, Drug Safety and Metabolism, Otsuka Pharmaceutical Factory, Inc, Naruto, Tokushima, Japan
    Exp Anim 55:49-56. 2006
    ..The antiseptic effects of an ointment and a lotion containing chlorhexidine gluconate were confirmed using this animal model...
  68. ncbi Skin capacitance in normal and atopic infants, and effects of moisturizers on atopic skin
    Tomoaki Matsumoto
    Department of Child Development, Graduate School of Medical Sciences, School of Medicine, Kumamoto University, Kumamoto, Japan
    J Dermatol 34:447-50. 2007
    ..The reference values for skin capacitance may be helpful for delineating normal from atopic skin. Certain moisturizers can increase skin hydration...
  69. ncbi An in vivo model to evaluate the efficacy of barrier creams on the level of skin penetration of chemicals
    Alexa Teichmann
    Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Medical Faculty Charité, Schumannstr 20 21, 10117 Berlin, Germany
    Contact Dermatitis 54:5-13. 2006
    ....
  70. doi Kinetics of moisturizing and firming effects of cosmetic formulations
    E Xhauflaire-Uhoda
    Department of Dermatopathology, University Hospital of Liege, Liege, Belgium
    Int J Cosmet Sci 30:131-8. 2008
    ..A sustained tensor (firming) effect was observed during treatment with both the lotion and the cream. However, no remnant firming effect was perceived after stopping treatment...
  71. ncbi In vivo measurement of human skin absorption of topically applied substances by a photoacoustic technique
    G Gutierrez-Juarez
    Instituto de Fisica, Universidad de Guanajuato, Gto, Mexico
    Physiol Meas 23:521-32. 2002
    ..The time constants associated with the rates of absorption, were found to vary in the range between 10 and 58 min, depending on the substance and the part of the body...
  72. ncbi Topical tacrolimus 0.1% ointment (protopic) reverses nickel contact dermatitis elicited by allergen challenge to a similar degree to mometasone furoate 0.1% with greater suppression of late erythema
    A Alomar
    Department of Dermatology, Hospital Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain
    Contact Dermatitis 49:185-8. 2003
    ..5). This method might provide useful means to compare different concentrations and/or presentations of tacrolimus or other calcineurin inhibitors and topical anti-inflammatory agents...
  73. ncbi Moisturizer technology versus clinical performance
    A V Rawlings
    AVR Consulting, Ltd, Cheshire, UK
    Dermatol Ther 17:49-56. 2004
    ..The complementary occlusive activity of emollients contributes to SC hydration as well...
  74. ncbi Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity
    Sarah L Chamlin
    Department of Dermatology, University of California, San Francisco, USA
    J Am Acad Dermatol 47:198-208. 2002
    ..Yet commonly used emollients and moisturizers do not correct the SC ceramide deficiency, the putative cause of the barrier abnormality.
  75. ncbi [NMF and cosmetology of cutaneous hydration]
    J P Marty
    Laboratoire de Dermopharmacologie et Cosmétologie, Faculte de Pharmacie, 5, rue J B Clement, 92296 Chatenay Malabry Cedex
    Ann Dermatol Venereol 129:131-6. 2002
    ....
  76. ncbi Integration of moisturizers and cleansers into a busy dermatology practice
    Robert Higham
    Mid Valley Dermatology and Cosmetic Surgery Center, Sherman Oaks, California, USA
    Cutis 76:32-3. 2005
    ..Incorporating these tips into a dermatology practice may provide patients with the desired information and may improve the clinical outcomes of patients with these often challenging dermatologic conditions...
  77. ncbi Doxepin affects acetylcholine induced cutaneous reactions in atopic eczema
    D Groene
    Department of Dermatology, University of Erlangen-Nuremberg, 91052 Erlangen, Germany
    Exp Dermatol 10:110-7. 2001
    ..This is probably caused by rehydrating and moisturizing effects...
  78. ncbi Improved risk-benefit ratio for topical triamcinolone acetonide in Transfersome in comparison with equipotent cream and ointment: a randomized controlled trial
    H Fesq
    Department of Dermatology and Allergy, Technical University Munich, Biedersteinerstr 29, 80802 Munich, Germany
    Br J Dermatol 149:611-9. 2003
    ..Transfersome is a drug delivery technology based on highly deformable, ultraflexible lipid vesicles which penetrate the skin when applied non-occlusively...
  79. ncbi Hydration and plasticity following long-term use of a moisturizer: a single-blind study
    Gregor B E Jemec
    Department of Medicine, Roskilde Hospital, Denmark
    Acta Derm Venereol 82:322-4. 2002
    ..No dose-response effect was seen, however. Long-term use of moisturizers increases skin capacitance significantly, but does not change the mechanical properties. In vivo skin hydration is a poor predictor of skin mechanics...
  80. ncbi Friction coefficient of skin in real-time
    Raja K Sivamani
    Center for Tribology, Inc, Campbell, CA, USA
    Skin Res Technol 9:235-9. 2003
    ....
  81. ncbi Intact skin--an integrity not to be lost
    R Gary Sibbald
    Department of Medicine, University of Toronto
    Ostomy Wound Manage 49:27-8, 30, 33 passim, contd. 2003
    ..The healthcare provider's role in this team should emphasize continuity of care, patient satisfaction, and product selection - all vital to protecting skin integrity...
  82. ncbi The skin barrier and use of moisturizers in atopic dermatitis
    Marie Lodén
    Research and Development Department, ACO Hud, Sweden
    Clin Dermatol 21:145-57. 2003
  83. pmc Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema
    K S Thomas
    Centre of Evidence Based Dermatology, Queen s Medial Centre, Nottingham NG7 2UH
    BMJ 324:768. 2002
    ..To determine whether a three day burst of a potent corticosteroid is more effective than a mild preparation used for seven days in children with mild or moderate atopic eczema...
  84. ncbi Adjunctive skin care in the management of rosacea: cleansers, moisturizers, and photoprotectants
    James Q Del Rosso
    Department of Dermatology, University of Nevada School of Medicine, Las Vegas, USA
    Cutis 75:17-21; discussion 33-6. 2005
    ..This review summarizes information regarding 3 classes of these products--cleansers, moisturizers, and photoprotectants--with emphasis on barrier function and skin irritation...
  85. doi Wound Care Product Primer for the Nurse Practitioner: Part II
    Kimberly Bookout
    Children s Medical Center, Dallas TX 75235, USA
    J Pediatr Health Care 22:205-7. 2008
  86. ncbi Moisturizers: what they are and how they work
    C W Lynde
    Department of Dermatology, University of Toronto, Toronto, Ontario, Canada
    Skin Therapy Lett 6:3-5. 2001
    ..Different classes of moisturizers are based on their mechanism of action, including occlusives, humectants, emollients and protein rejuvenators...
  87. ncbi Intermittent dosing of fluticasone propionate cream for reducing the risk of relapse in atopic dermatitis patients
    J Hanifin
    Oregon Health Sciences University, Portland OR, U S A
    Br J Dermatol 147:528-37. 2002
    ..One of the most troublesome features of atopic dermatitis (AD) is its chronic relapsing nature, and there is a lack of published evidence on the best treatment strategy for long-term management of the disease...
  88. ncbi A guide to emollient therapy
    Allyson Brown
    Skin and Wound Care Service, Plymouth Hospitals NHS Trust, Plymouth
    Nurs Stand 19:68, 70, 72 passim. 2005
    Although the benefits of emollient therapy have been widely acknowledged in dermatology treatments (Cork 1997), emollients have tended to be undervalued and under-used in general care and wound management...
  89. ncbi The safety of calcitriol 3 microg/g ointment. Evaluation of cutaneous contact sensitization, cumulative irritancy, photoallergic contact sensitization and phototoxicity
    C Queille-Roussel
    CPCAD, , BP 3079, 06202 Nice cedex, France
    Eur J Dermatol 11:219-24. 2001
    ..These studies showed that calcitriol 3 microg/g ointment is a well-tolerated treatment for stable plaque-type psoriasis...
  90. ncbi Some Nigerian plants of dermatologic importance
    Frances O A Ajose
    Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria
    Int J Dermatol 46:48-55. 2007
    ..Nigerians still depend largely on crude herbal remedies or traditional medicine. They also use wild plants for cosmetics and perfumery. Some of these herbal remedies have been observed to be effective in certain skin diseases...
  91. ncbi [Pruritus and the hepatitis C virus. The MULTIVIRC Unit]
    H Dega
    , , Paris
    Ann Dermatol Venereol 125:9-12. 1998
    ..Dermatology treatment associated antihistamine agents, emollients, and corticosteroids. This population of hepatology patients referred for pruritis comprised 2.5 p...
  92. ncbi Bacterial skin infections in the elderly: diagnosis and treatment
    Simone Laube
    Department of Dermatology, University Hospital of Wales, Cardiff, Wales, UK
    Drugs Aging 19:331-42. 2002
    ..b>Emollients and antihistamines are useful measures...
  93. ncbi The world's longest surviving paediatric practices: some themes of Aboriginal medical ethnobotany in Australia
    John Pearn
    Department of Paediatrics and Child Health Royal Children s Hospital, Brisbane, QLD, Australia
    J Paediatr Child Health 41:284-90. 2005
    ..They are prepared as infusions, decoctions and macerations and may be enjoined with emollients such as emu or kangaroo fat for topical application...
  94. ncbi Food-induced acute generalized exanthematous pustulosis in a pregnant woman
    Sonya Valkova
    Department of Dermatology and Venereology, University Hospital, Pleven, Bulgaria
    Skinmed 5:199-201. 2006
    ..05%, and emollients. As a result, her fever disappeared and her erythema faded...
  95. ncbi [Pellagra]
    Palokinam T Pitche
    Service de Dermatologie, CHU Tokoin, Faculté de médecine et de pharmacie de Lomé, BP 81056 Lomé, Togo
    Sante 15:205-8. 2005
    ..Topical management of skin lesions with emollients may reduce discomfort...
  96. pmc Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs
    Gunter Kampf
    Bode Chemie GmbH and Co, Scientific Affairs, Melanchthonstrasse 27, 22525 Hamburg, Germany
    Clin Microbiol Rev 17:863-93, table of contents. 2004
    ..Centers for Disease Control and Prevention guideline, promotion of alcohol-based hand rubs containing various emollients instead of irritating soaps and detergents is one strategy to reduce skin damage, dryness, and irritation...
  97. ncbi Cutaneous reactions due to diltiazem and cross reactivity with other calcium channel blockers
    M A Gonzalo Garijo
    Servico de Alergologia, Hospital Universitario Infanta Cristina, Badajoz, Spain
    Allergol Immunopathol (Madr) 33:238-40. 2005
    ..Patch testing has been used as confirmatory testing in patients with extensive cutaneous reactions. Cross-reactivity among these drugs have not been established...
  98. ncbi Exacerbation of allergic contact dermatitis during immunosuppression with cyclosporine A
    F Prignano
    Interuniversitary Center of Biologic and Psychosomatic Dermatology, University of Florence, Florence, Italy
    G Ital Dermatol Venereol 145:543-6. 2010
    ..Topical treatments consist of bland emollients, corticosteroids ointments, topical immunomodulators such as tacrolimus and pimecrolimus ointments, coal tar and ..
  99. ncbi Diagnostic dilemma: crusted scabies superimposed on psoriatic erythroderma in a patient with acquired immunodeficiency syndrome
    Brian S Fuchs
    Department of Dermatology, Mount Sinai School of Medicine, 1 Gustave L Levy Place, New York, NY 10029, USA
    Skinmed 6:142-4. 2007
    ..The patient had been diagnosed with psoriasis 2 years previously, and at the time of presentation was using emollients and topical corticosteroid creams with little improvement...
  100. ncbi Efficacy and safety of pimecrolimus cream in the long-term management of atopic dermatitis in children
    Ulrich Wahn
    Department of Pediatric Pneumology and Immunology, Charite, Humboldt University, Berlin, Germany
    Pediatrics 110:e2. 2002
    ..We assessed whether early treatment of AD signs/symptoms with pimecrolimus could influence long-term outcome by preventing disease flares...
  101. ncbi Local narrowband UVB phototherapy vs. local PUVA in the treatment of chronic hand eczema
    Engin Sezer
    Department of Dermatology, Gaziosmanpasa University School of Medicine, Tokat, Turkey
    Photodermatol Photoimmunol Photomed 23:10-4. 2007
    ..The aim of our study was to compare the efficacy and safety of local narrowband UVB phototherapy with paint-PUVA in patients with chronic hand eczema of dry and dyshidrotic types unresponsive to conventional therapies...

Research Grants56

  1. Impact of Sunflower Oil Massage on Neonatal Mortality in Nepal
    Luke C Mullany; Fiscal Year: 2010
    ..There is increasing evidence of the role of the neonatal skin and the potential for newborn massage with topical emollients in providing protection from invasive pathogens...
  2. Novel Topical Treatment for Disorders of Keratinization
    Bakul Bhatt; Fiscal Year: 2005
    ..Current treatment options include the use of emollients and moisturizers, and keratolytic agents including salicylic acid, urea, or alpha hydroxy acids...
  3. GANGLIOSIDE GENE MODULATION EFFECT ON CELL MOTILITY
    Amy Paller; Fiscal Year: 2007
    ..These studies will provide information about the role of gangliosides in caveolin-1 mediated signaling and may lead to novel therapies for patients with abnormal healing responses. ..
  4. GANGLIOSIDE GENE MODULATION EFFECT ON CELL MOTILITY
    Amy Paller; Fiscal Year: 2002
    ....
  5. Applied Research in Antimicrobial Resistance: Studies of Susceptibility Testing
    Lisa Saiman; Fiscal Year: 2007
    ..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
  6. Outcomes of Omission of Radiation With Lumpectomy (BCS) Among Low-Income Women
    Roger Anderson; Fiscal Year: 2007
    ..abstract_text> ..
  7. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Saiman; Fiscal Year: 2009
    ..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
  8. Improving Antimicrobial Prescribing Practices in the Neonatal Intensive Care Unit
    Lisa Saiman; Fiscal Year: 2010
    ..abstract_text> ..
  9. Improving Antimicrobial Prescribing Practices in the Neonatal Intensive Care Unit
    Lisa Saiman; Fiscal Year: 2009
    ..abstract_text> ..
  10. Training in Interdisciplinary Research to Reduce Antimicrobial Resistance (TIRAR)
    Elaine Larson; Fiscal Year: 2009
    ..These evaluationswill be a focal point of discussion in the Faculty Development Seminar, and suitable program modifications will be implemented by the Leadership Team. ..
  11. Distribution of the Costs of Antimicrobial Resistant Infections
    ELAINE LUCILLE LARSON; Fiscal Year: 2010
    ..The analyses will match patients with resistant infections (hospital- and community-acquired) to susceptible patients and to uninfected patients. _^ ..
  12. Training in Interdisciplinary Research to Reduce Antimicrobial Resistance (TIRAR)
    ELAINE LUCILLE LARSON; Fiscal Year: 2010
    ..These evaluationswill be a focal point of discussion in the Faculty Development Seminar, and suitable program modifications will be implemented by the Leadership Team. ..
  13. Patterns of Patient Care in Appalachia
    Roger T Anderson; Fiscal Year: 2010
    ..g., high volume of cancer care, comprehensive treatment center and oncologist practice);and (iii) Facility volume, type, comprehensiveness and accredited status, and surgeon case volume, training status, and vintage. ..
  14. Breast and Prostate Cancer Data Quality and Patterns of Care Study in NC
    Roger Anderson; Fiscal Year: 2007
    ..5) Participate in the analysis of aggregate data and follow common protocols of the collaborative PoC group. ..
  15. Outcomes of Omission of Radiation With Lumpectomy (BCS) Among Low-Income Women
    Roger Anderson; Fiscal Year: 2007
    ....
  16. Staff Hand Hygiene and Nosocomial Infections in Neonates
    Elaine Larson; Fiscal Year: 2003
    ....
  17. STAFF HAND HYGIENE AND NOSOCOMIAL INFECTION IN NEONATES
    Elaine Larson; Fiscal Year: 2003
    ..Results of this study can be generalized to many clinical settings. ..
  18. HOME HYGIENE INTERVENTION
    Elaine Larson; Fiscal Year: 2002
    ..Logistic regression, Liang-Zeger regression, and Chi Square analyses will be used to test differences in rates of transmission of symptoms and changes in quantity, types and resistance patterns of microbial flora of the hands. ..
  19. Phase I Clinical Trials of New Anticancer Agents
    Patricia LoRusso; Fiscal Year: 2007
    ....
  20. Preterm Infants: Light Effects on Health and Development
    Debra Brandon; Fiscal Year: 2007
    ..abstract_text> ..
  21. Pimecrolius on T cell Responses in Atopic March
    Jonathan Spergel; Fiscal Year: 2007
    ..In third aim of the trial, we explore the effects of pimecrolimus as a disease-modifying agent in the prevention of asthma. Asthma phenotype will be examined by spirometry per and post-beta-2-agonist and exhaled nitric oxide. ..
  22. Interdisciplinary Research:Antimicrobial Resistance(RMI)
    Elaine Larson; Fiscal Year: 2006
    ..In the final year, plans for a sustainable Consortium on antimicrobial resistance will be formalized. ..
  23. Impact of Hand Hygiene Guideline on Infections and Costs
    Elaine Larson; Fiscal Year: 2005
    ..abstract_text> ..