psychotropic drugs

b>Psychotropic drugs acting on monoamine neurotransmission are major pharmacological treatments for neuropsychiatric conditions such as schizophrenia, depression, bipolar disorder, Tourette syndrome, ADHD, and Alzheimer disease...

..In Austria, prevalence data are lacking. We aimed to determine the prevalence of psychotropic medication prescription in Austrian nursing homes and to explore characteristics associated with their prescription...

..To assess the consequences to mother and baby of abruptly discontinuing antidepressant or benzodiazepine medication during pregnancy and to assess the impact of our counselling...

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..Exemplars of innovative prescribing models, involving pharmacists and encouraging resident-centred care, may offer a more palatable approach to improving drug use in this vulnerable population...

..In addition, exposure to psychotropic drugs or stress regulates the rate of neurogenesis in adult brain, suggesting a possible role for neurogenesis in ..

..The five-choice serial reaction time task (5CSRTT) is one such model. Here, we characterized the effects of four standard psychotropic agents on performance in the 5CSRTT...

..Moreover, the evidence for significant drug-drug interactions involving psychotropic drugs in rodents is considered...

..Our objective was to describe the use of psychotropic drugs in all long-term nursing home residents > or =65 years of age with and without dementia in Helsinki, Finland...

..The rationale for use of psychotropic medications in FD is apparent but the evidence base to support the use of antidepressant pharmacotherapy is to date limited...

..For example, an optimal dose of D2 antagonist antipsychotics produces occupancy of 65% to 80% of D2 receptors, while a greater dose carries a risk of extrapyramidal side effects...

..The most commonly used psychotropic drugs as it related to the residents' problems were: benzodiazepines (oxazepam) against anxiety, benzodiazepine-..

..Finally, awareness of a severe withdrawal syndrome from GHB and its precursors is particularly important to psychiatrists of the medically ill, who may be called on to help in the management of these patients...

Weight gain is a common adverse effect of psychotropic drugs. Clinically significant weight gain puts the patient at risk for coronary heart disease, hypertension, Type II diabetes, dyslipidaemia and cancer, and can lead to non-compliance,..

..in six facilities received a standardized assessment (Neuropsychiatric Inventory [NPI], Barthel Scale, psychotropic drugs)...

..Their use as industrial tools for drug evaluation requires specific, dedicated development...

..to determine the frequency and risk of appearance of adverse drug reactions/ADRs/during the treatment with psychotropic drugs. The first part of the study is an analysis of the use of the psychotropic drugs for one-year period of time ..

..To describe the prevalence of various psychiatric and behavioral symptoms among patients with dementia in nursing homes and acute geriatric wards and to investigate the administration of psychotropic medications to these patients...

..To assess the prescribing practice, use and potential adverse effects of psychoactive medications in Singapore nursing homes...

..It is concluded that pure placebo-controlled clinical trials of new psychotropic drugs may be acceptable in minor psychic disorders, but in general -- at least in a pure form -- not in major ..

..Proteomic research using CSF will hopefully have a major impact on the development of treatments for psychiatric disorders...

..He had taken many psychotropic drugs as treatment for schizophrenia and was very dehydrated...

BACKGROUND: The use of psychotropic drugs is high in institutionalised elderly, which raises the question of its appropriateness...

..Lysosomal trapping is an important mechanism of distribution of basic psychotropic drugs; however, the tissue distribution of the aliphatic-type phenothiazine neuroleptic promazine, tricyclic ..

..Some psychotropic drugs, particularly tricyclic antidepressants (TCAs) and antipsychotic agents, are correlated with iatrogenic ..

..1%. From these results it can be concluded that the OraSure OSCD is useful to collect oral fluid for reliable quantitative THC assay applying a modified elution procedure and gravimetric determination of the amount of oral fluid...

..The authors examined whether working in downsizing organisations predicts use of psychotropic drugs among employees who remain in employment.

..5) with no difference between chronic and occasional users. The large inter- and intraindividual variability observed precludes a reliable estimation of THC serum concentrations from oral fluid data using this collection device...

..The authors argue that mental health nurses must play an active role in health promotion, primary prevention, and the early detection and management of physical health problems in all areas of clinical practice...

..For psychoactive drugs, animal studies have shown that plasma concentrations of psychotropic drugs correlate well with concentrations in the target organ, the brain...

..However, routine application of pharmacogenetic dose adjustment in clinical practice requires prospective validation...

Neuropsychiatric symptoms in dementia patients are common and are often treated with psychotropic drugs. The aim of this study was to determine the prevalence and correlates of psychotropic drug use in Dutch nursing home patients with ..

Pharmacoendocrinological studies have shown that psychotropic drugs with different actions have different effects on anterior pituitary hormone secretion in man...

b>Psychotropic Drugs and ST Segment Elevation. Transient ST segment elevation in right precordial leads with use of psychotropic drugs is reported in two cases of overdose and one case of therapeutic administration...

This study aims to better understand the contributions of occupation and work organization conditions to the development of chronic psychotropic drugs use among workers in Canada.

Psychiatric and behavioural symptoms in dementia are associated with a range of negative outcomes, including institutional placement and the widespread use of psychotropic drugs in spite of limited evidence for their efficacy.

..The causes for increased prescription of psychotropic drugs other than mental disorders have been discussed...

..This study aimed to describe the extent and patterns of psychotropic medication use in children and adolescents enrolled in a large health plan (MGEN) in France, and its evolution in recent years...

..Preventive measures should be taken to make adolescents and their parents more aware of the risks and to improve their living conditions...

..The aim of the present proof-of-principle study was to investigate whether such drugs also affect lipid transport and export pathways in cultured human CNS and liver cells...

..CONCLUSION: By means of this model, a new concept of "medicine-on-demand" will be suggested: a subjective medicine with a physician's recommendation and veto right...

..The risk factors associated with khat chewing are described, with emphasis on the reported increased incidence of acute myocardial infarction...

..CONCLUSIONS: These findings show that functional regulation of presynaptic CaM kinase II is selectively affected by different psychotropic drugs, and suggest local synaptic mechanisms for pharmacological regulation of the kinase.

..clear understanding of the pharmacodynamic and pharmacokinetic interactions between antiepileptic drugs and psychotropic drugs is of the essence to avert unnecessary adverse events and loss of efficacy of psychotropic drugs...

..The detailed course and pattern of illness emerging despite comprehensive treatment with mood stabilizers and adjunctive agents have previously not been well delineated...

To study whether listed putative corrected QT (QTc)-prolonging psychotropic drugs indeed prolong the QTc interval under everyday circumstances and to evaluate whether this is a class effect or an individual drug effect, we conducted a ..

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..This article aims to review the implications of pharmacogenetics for clinical psychiatry; these are discussed in the context of environmental and sociocultural factors...

..Well-known causes of liver injury such as chlorpromazine, phenytoin, and methyldopa are not discussed...

..In this study, we investigated the effects of a range of psychotropic drugs on rat brain metabolites...

..At present, there is insufficient information regarding the pattern of psychoactive substance use among this group of children in Nigeria...

..Treatment approaches that combine efficacious medications and empirically proven behavioral interventions, such as voucher-based reinforcement therapy, will almost certainly produce the best results...

b>Psychotropic drugs, especially antidepressants and antipsychotics, may give rise to some concern in clinical practice because of their known ability to reduce seizure threshold and to provoke epileptic seizures...

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..Sudden death has been associated with certain psychotropic drugs and the underlying cause(s) have been suggested to be some adverse cardiac complications...

..We examined the prevalence and determinants of the reasons given for non-adherence to psychiatric medication in a representative community survey...

..However, the increase in Dutch stimulant use agrees with the previously reported 2.5-fold increase in the United States and shows that the increased use of stimulants is not limited to the United States...

To assess if use of psychotropic drugs is associated with an increased risk of admission for heat-related pathologies during a heat wave period.

..We recommend that future disarmament, demobilization, and reintegration (DDR) programs need to be prepared to deal with significant drug-related problems in Somalia...

..and density of lysosomes may vary in its different regions), in the present study we examined the uptake of psychotropic drugs by vertically cut slices of whole brain, grey (cerebral cortex) and white (corpus callosum, internal capsule)..

..To characterise the prescription pattern of psychotropics in Danish nursing homes and to identify diagnostic, behavioural, cognitive and performance characteristics associated with prevalent psychotropic drug use...

..Identifying people with probable mental health disorders as they enter treatment has the potential to increase access to care among those with limited prior access...

..This report provides a survey of this shared decision making model and a discussion of its implications in the fields of mental health and neurology...

..Greater awareness of these problems, empirical research, and education about mental health issues in the sports medicine community is clearly needed...

..The importance of classification for risk estimation of delinquent behaviour and its significance for providing forensic opinions is discussed...

..To assess the contribution of sociodemographic and psychopathologic predictors for suicide in alcohol-related disorders and in substance-related disorders in general and to examine the constellations of risk factors for suicide...

..This parameter considers risk factors for substance use and related problems, normative use of substances by adolescents, the comorbidity of substance use disorders with other psychiatric disorders, and treatment settings and modalities...

..This may reflect value consumers place on staff time, attention and communication. Teaching may enhance self-efficacy and hope thereby facilitating recovery...

..Current treatment options and implications for future research are highlighted...

..The purpose of this study was to assess the prevalence of axis I disorders among patients with borderline personality disorder over 6 years of prospective follow-up...

..The difference between self-reported use and prescriptions filled may reflect compliance problems in psychiatric treatment...

..Psychiatrists complied more with current guidelines. Implications of the findings are discussed...

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..Is an inferior outcome of psychiatric rehabilitation to be expected with patients who consume alcohol or addictive drugs in a problematic manner during rehabilitation treatment?..

..Thus, research and clinical efforts should focus on risk factors for psychological distress in women and on preventive measures beyond the post-partum period...

..33), indicating a possible adverse effect. Prevention of new cases of mental disorders seems to be possible and may be an important way of reducing the enormous burden of these disorders...

..Findings suggest problems or barriers to the provision of services that need to be investigated among this vulnerable community population...

..The objective of this study was to estimate rates of medication switching among dually eligible beneficiaries using antidepressants, antipsychotics, and mood stabilizers attributable to their enrollment in Medicare drug plans...

..The aim of this study is to document the sociodemographic and the clinical profile of patients who are on antipsychotic (AP) medication prescribed in outpatient mental health clinic of a university hospital...

The objective of the study was to provide observational clinical data on psychotropic drugs used in older people with mental illness.

..The characteristics associated with symptoms of abuse and/or dependence related to prescription medication misuse among adolescents were also analyzed...

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..Cognitive behavioural therapy has been shown to contribute to positive treatment outcomes for a range of mental health problems, including schizophrenia and substance abuse...

..The keywords aggression, violence, anger, and hostility combined with drug therapy, psychotropic drugs, adrenergic beta-antagonists, anticonvulsants, anti-depressants, antipsychotic agents, benzodiazepines, and ..

..The stages of change, the stages of treatment, and the psychosocial strategies used at each stage of treatment are outlined...

..This study examined changes in the use of psychotropic agents in Taiwan between 1997 and 2004...

..Sixty-three TMD patients were investigated using clinical and anamnestical psychiatric informations and psychopathological measures...

..This study describes the treatment of mental health problems in general practice as diagnosed by general practitioners (GP)...

..Prevention of adolescent substance use and misuse should aim at these different targets. Information about coping with peer pressure may be a particularly promising route of intervention...

..These can be additional sources of patient distress during interferon therapy and require appropriate intervention through patient education, psychotropic medications, support, and behavioral techniques...

..To get to know the profile of use of antidepressants (AD) and tranquilizers-hypnotics (T-H) in primary care in Catalonia...

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..The most common medical diagnoses were epilepsy, drug overdose, ambiguous genitalia, orthopaedic injuries and diabetes mellitus.Young people with these medical problems are in real need of psychological assessment and intervention...

..pharmacological treatment with antipsychotics, antidepressants, cholinesterase inhibitors, and other psychotropic drugs. They conclude that although these medications have some beneficial effects, no intervention is currently ..

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..In this review we discussed the current evidence of the teratogenic risks with psychotropic drugs commonly used to treat psychiatric disorders and also focused on decision making in such patients.

..grant has supported our research on fundamental neurochemical mechanisms which may underlie the actions of psychotropic drugs. In recent years we have characterized novel neurotransmitters such as nitric oxide and D-serine, areas ..

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..The effect of THC on the secretion of the co-stimulatory signal interleukin-1, requisite for replication of T-helper cells in addition to antigen receptor occupancy, will be established using C3H/HeJ mouse thymocyte proliferation...

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..In addition to providing new information about determinants of two licit forms of drug taking behavior which produce significant health risk, these studies will provide an improved understanding of the nature of the addictive process...

..The affinity reagents and the binding domain data obtained from these reagents will be important in defining the mechanisms of these ubiquitous and varied molecular switches. ..

..We will also use cytokine injections of non-infected mothers to help identify cytokines that may mediate the effects of maternal viral infection. ..

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..The proposed tracers for imaging SERT can be prepared by regional radiopharmacies and distributed within any major metropolitan area benefiting a large number of patients undergoing antidepressant treatment. ..

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..Collectively, these studies will provide fundamentally new information on the in vivo pharmacology of GABAA modulators and will help to identify the pharmacologic and behavioral determinants of physical dependence on sedative hypnotics. ..

..Through these studies, a comprehensive pre-clinical evaluation of the effects of chronic methylphenidate on learning, behavior, brain function and molecular patterns will be completed. ..

..The studies are multidisciplinary. They involve only human volunteers. The research will further understanding psychoactive drug use, health consequences and management. ..

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..especially if they are withdrawn abruptly from the medication or switched to less appropriate or efficacious psychotropic drugs. We examine the implications of the loss of BZD coverage resulting from the Medicare Part D exclusion using ..

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