xylitol

Summary

Summary: A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.

Top Publications

  1. ncbi The use of sorbitol- and xylitol-sweetened chewing gum in caries control
    Brian A Burt
    Department of Epidemiology, School of Public Health, University of Michigan, 109 Observatory St, Ann Arbor, Mich 48109 2029, USA
    J Am Dent Assoc 137:190-6. 2006
  2. ncbi Effect of xylitol chewing gum on salivary Streptococcus mutans in preschool children
    Jaana T Autio
    Department of Operative Dentistry, University of Florida, Gainesville, Florida, USA
    ASDC J Dent Child 69:81-6, 13. 2002
  3. ncbi Xylitol production from corn fiber and sugarcane bagasse hydrolysates by Candida tropicalis
    R Sreenivas Rao
    Department of Microbiology, Osmania University, Hyderabad, India
    Bioresour Technol 97:1974-8. 2006
  4. ncbi Increase of xylitol production rate by controlling redox potential in Candida parapsilosis
    D K Oh
    Department of Food Science and Technology, Woosuk University, Cheonju 565 800, Korea
    Biotechnol Bioeng 58:440-4. 1998
  5. ncbi Synergistic inhibition by combination of fluoride and xylitol on glycolysis by mutans streptococci and its biochemical mechanism
    H Maehara
    Department of Lifelong Oral Health Sciences, Division of Pediatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Caries Res 39:521-8. 2005
  6. ncbi Analysis of NADPH supply during xylitol production by engineered Escherichia coli
    Jonathan W Chin
    Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Biotechnol Bioeng 102:209-20. 2009
  7. ncbi Engineering of a matched pair of xylose reductase and xylitol dehydrogenase for xylose fermentation by Saccharomyces cerevisiae
    Stefan Krahulec
    Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Austria
    Biotechnol J 4:684-94. 2009
  8. ncbi Production of xylitol from D-xylose by a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis
    Byoung Sam Ko
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea
    Appl Environ Microbiol 72:4207-13. 2006
  9. ncbi Production of 2,3-butanediol from corncob molasses, a waste by-product in xylitol production
    Ailong Wang
    State Key Laboratory of Microbial Technology, Shandong University, Jinan, 250100, People s Republic of China
    Appl Microbiol Biotechnol 87:965-70. 2010
  10. ncbi Antihyperlipidemic activity of 3-hydroxymethyl xylitol, a novel antidiabetic compound isolated from Casearia esculenta (Roxb.) root, in streptozotocin-diabetic rats
    Govindasamy Chandramohan
    Community Health Sciences Department, College of Applied Medical Sciences, King Saud University, P O Box 10219, Riyadh 11433, Kingdom of Saudi Arabia
    J Biochem Mol Toxicol 24:95-101. 2010

Research Grants

  1. Xylitol Adult Caries Trial (X-ACT)--UNC Clinical Center
    Daniel Shugars; Fiscal Year: 2007
  2. Xylitol Adult Caries Trial (X-ACT)--Study Chair application
    James Bader; Fiscal Year: 2007
  3. PREVENT TRANSMIS OF MUTANS STREPTOC FR MOTHER TO CHILD
    Walter Bretz; Fiscal Year: 2004
  4. Xylitol Adult Caries Trial (X-ACT): UAB Clinical Center
    GREGG GILBERT; Fiscal Year: 2007
  5. Xylitol Adult Caries Trial (X-ACT) UTHSC San Antonio Clinical Center
    Bennett Amaechi; Fiscal Year: 2007
  6. Identification of anti-cariogenic/low-glycemic activity factors from Lo Han Kuo
    CHIFU HUANG; Fiscal Year: 2006
  7. Xylitol Adult Caries Trial (X-ACT) Data Coordinating Center
    William Vollmer; Fiscal Year: 2007
  8. Structural Basis of Selective Permeability in Aquaporin
    Dax Fu; Fiscal Year: 2006
  9. Planning Grant for Xylitol Trial in Caries-Active Adults
    James Bader; Fiscal Year: 2005
  10. Fluoride Varnish to Prevent Caries in Toddlers - An Expanded Immunization Program
    Peter Milgrom; Fiscal Year: 2007

Detail Information

Publications227 found, 100 shown here

  1. ncbi The use of sorbitol- and xylitol-sweetened chewing gum in caries control
    Brian A Burt
    Department of Epidemiology, School of Public Health, University of Michigan, 109 Observatory St, Ann Arbor, Mich 48109 2029, USA
    J Am Dent Assoc 137:190-6. 2006
    The author compared the caries-inhibitory action of sorbitol- and xylitol-sweetened chewing gum and assessed the role of these products in caries prevention.
  2. ncbi Effect of xylitol chewing gum on salivary Streptococcus mutans in preschool children
    Jaana T Autio
    Department of Operative Dentistry, University of Florida, Gainesville, Florida, USA
    ASDC J Dent Child 69:81-6, 13. 2002
    ..The purpose of this study was to evaluate the effect of xylitol gum in salivary S. mutans levels in preschool children...
  3. ncbi Xylitol production from corn fiber and sugarcane bagasse hydrolysates by Candida tropicalis
    R Sreenivas Rao
    Department of Microbiology, Osmania University, Hyderabad, India
    Bioresour Technol 97:1974-8. 2006
    A natural isolate, Candida tropicalis was tested for xylitol production from corn fiber and sugarcane bagasse hydrolysates...
  4. ncbi Increase of xylitol production rate by controlling redox potential in Candida parapsilosis
    D K Oh
    Department of Food Science and Technology, Woosuk University, Cheonju 565 800, Korea
    Biotechnol Bioeng 58:440-4. 1998
    The effect of redox potential on xylitol production by Candida parapsilosis was investigated...
  5. ncbi Synergistic inhibition by combination of fluoride and xylitol on glycolysis by mutans streptococci and its biochemical mechanism
    H Maehara
    Department of Lifelong Oral Health Sciences, Division of Pediatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Caries Res 39:521-8. 2005
    The purpose of this study was to evaluate the combined inhibitory effect of fluoride and xylitol on acid production by mutans streptococci, Streptococcus mutans NCTC10449 and Streptococcus sobrinus 6715, from glucose under strictly ..
  6. ncbi Analysis of NADPH supply during xylitol production by engineered Escherichia coli
    Jonathan W Chin
    Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Biotechnol Bioeng 102:209-20. 2009
    ..expressing an NADPH-dependent xylose reductase from Candida boidinii (CbXR) was previously reported to produce xylitol from xylose while metabolizing glucose [Cirino et al. (2006) Biotechnol Bioeng 95(6): 1167-1176]...
  7. ncbi Engineering of a matched pair of xylose reductase and xylitol dehydrogenase for xylose fermentation by Saccharomyces cerevisiae
    Stefan Krahulec
    Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Austria
    Biotechnol J 4:684-94. 2009
    ..of nicotinamide adenine dinucleotide (phosphate) NAD(P)H-dependent xylose reductase (XR) and NAD(+)-dependent xylitol dehydrogenase (XDH)...
  8. ncbi Production of xylitol from D-xylose by a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis
    Byoung Sam Ko
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea
    Appl Environ Microbiol 72:4207-13. 2006
    b>Xylitol dehydrogenase (XDH) is one of the key enzymes in d-xylose metabolism, catalyzing the oxidation of xylitol to d-xylulose...
  9. ncbi Production of 2,3-butanediol from corncob molasses, a waste by-product in xylitol production
    Ailong Wang
    State Key Laboratory of Microbial Technology, Shandong University, Jinan, 250100, People s Republic of China
    Appl Microbiol Biotechnol 87:965-70. 2010
    Corncob molasses, a waste by-product in xylitol production, contains high concentrations of mixed sugars. In the present study, corncob molasses was used to produce 2,3-butanediol (BD) using Klebsiella pneumoniae SDM...
  10. ncbi Antihyperlipidemic activity of 3-hydroxymethyl xylitol, a novel antidiabetic compound isolated from Casearia esculenta (Roxb.) root, in streptozotocin-diabetic rats
    Govindasamy Chandramohan
    Community Health Sciences Department, College of Applied Medical Sciences, King Saud University, P O Box 10219, Riyadh 11433, Kingdom of Saudi Arabia
    J Biochem Mol Toxicol 24:95-101. 2010
    ..An active compound, 3-hydroxymethyl xylitol (3-HMX), has been isolated, and its optimum dose has been determined in a short duration study and patented...
  11. ncbi Xylitol production by a Pichia stipitis D-xylulokinase mutant
    Yong-Su Jin
    Department of Food Science, University of Wisconsin-Madison, 1550 Linden Drive, Madison, WI 53706, USA
    Appl Microbiol Biotechnol 68:42-5. 2005
    b>Xylitol production by Pichia stipitis FPL-YS30, a xyl3-delta1 mutant that metabolizes xylose using an alternative metabolic pathway, was investigated under aerobic and oxygen-limited culture conditions...
  12. ncbi In vitro testing of xylitol as an anticariogenic agent
    Paul S Sahni
    Indiana University, Indianapolis, USA
    Gen Dent 50:340-3. 2002
    A number of studies involving xylitol chewing gum have demonstrated that xylitol is both noncariogenic and anticariogenic...
  13. ncbi Optimization of acid hydrolysis of sugarcane bagasse and investigations on its fermentability for the production of xylitol by Candida guilliermondii
    Rafael Fogel
    , , Universidade Federal do Rio de Janeiro, RJ, CEP: 21949-900, Brazil
    Appl Biochem Biotechnol 121:741-52. 2005
    ..conversion (tC) to 75 h (without nitrogen source addition tC > 127 h), and, consequently, improving the rates of xylitol bioproduction...
  14. ncbi Tyr-51 is the proton donor-acceptor for NAD(H)-dependent interconversion of xylose and xylitol by Candida tenuis xylose reductase (AKR2B5)
    Simone L Pival
    Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Petersgasse 12, A 8010 Graz, Austria
    FEBS Lett 582:4095-9. 2008
    ..bromide brought about unidirectional rate enhancement ( approximately 2x10(3)-fold at 300mM) for NAD(+)-dependent xylitol oxidation by Y51A...
  15. ncbi Effect of xylitol-containing chewing gums on interdental plaque-pH in habitual xylitol consumers
    Pernilla Lif Holgerson
    Department of Odontology, Pediatric Dentistry, Faculty of Medicine, Umea University, Umea, Sweden
    Acta Odontol Scand 63:233-8. 2005
    The aim was to investigate the effect of high and low amounts of xylitol on the interdental plaque-pH, directly and after sucrose challenge, in schoolchildren with habitual consumption.
  16. ncbi Improved NADPH supply for xylitol production by engineered Escherichia coli with glycolytic mutations
    Jonathan W Chin
    Department of Chemical Engineering, Pennsylvania State University, University Park, PA 16802, USA
    Biotechnol Prog 27:333-41. 2011
    ..coli engineered to uptake xylose while metabolizing glucose was previously shown to produce high levels of xylitol from a mixture of glucose and xylose when expressing NADPH-dependent xylose reductase from Candida boidinii (CbXR)..
  17. ncbi Influence of maternal xylitol consumption on mother-child transmission of mutans streptococci: 6-year follow-up
    E Soderling
    Institute of Dentistry, University of Turku, Finland
    Caries Res 35:173-7. 2001
    b>Xylitol is effective as a noncariogenic or even cariostatic sugar substitute. Habitual xylitol consumption appears to select for mutans streptococci (MS) which shed easily into saliva from plaque...
  18. ncbi Role of xylose transporters in xylitol production from engineered Escherichia coli
    Reza Khankal
    Department of Chemical Engineering, Pennsylvania State University, University Park, PA 16802, USA
    J Biotechnol 134:246-52. 2008
    ..2006 [Cirino, P.C., Chin, J.W., Ingram, L.O., 2006. Engineering Escherichia coli for xylitol production from glucose-xylose mixtures. Biotechnol. Bioeng. 95, 1167-1176.])...
  19. ncbi Six months of daily high-dose xylitol in high-risk schoolchildren: a randomized clinical trial on plaque pH and salivary mutans streptococci
    G Campus
    Dental Institute, University of Sassari, Sassari, Italy
    Caries Res 43:455-61. 2009
    A randomized clinical trial was designed to evaluate the effect of daily high-dose xylitol chewing gum on plaque pH and salivary mutans streptococci (MS) in a sample of schoolchildren at high risk of caries...
  20. ncbi Microbiological purification of L-arabitol from xylitol mother liquor
    Mingguo Jiang
    College of Chemical Engineering and Ecology, Guangxi University for Nationality, Nanning, 530007, China
    J Microbiol Biotechnol 21:43-9. 2011
    ..Therefore, this study describes a novel L-arabitol production method based on biological purification from the xylitol mother liquor, a cheap and readily available raw material that contains a high concentration of Larabitol...
  21. ncbi Novel enzymatic method for the production of xylitol from D-arabitol by Gluconobacter oxydans
    Shun-ichi Suzuki
    AminoScience Laboratories, Ajinomoto Co, Inc, Suzuki-cho, Kawasaki-ku, Kawasaki-shi 210-8681, Japan
    Biosci Biotechnol Biochem 66:2614-20. 2002
    Microorganisms capable of producing xylitol from D-arabitol were screened for...
  22. ncbi Xylitol production from xylose mother liquor: a novel strategy that combines the use of recombinant Bacillus subtilis and Candida maltosa
    Hairong Cheng
    Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China
    Microb Cell Fact 10:5. 2011
    ..In China, more than 50,000 metric tons of xylose mother liquor was produced in 2009, and the management of sugars like xylose that present in the low-cost liquor is a problem...
  23. ncbi Cloning of the xylitol dehydrogenase gene from Gluconobacter oxydans and improved production of xylitol from D-arabitol
    Masakazu Sugiyama
    AminoScience Laboratories, Ajinomoto Co, Inc, Suzuki cho, Kawasaki ku, Kawasaki shi 210 8681, Japan
    Biosci Biotechnol Biochem 67:584-91. 2003
    b>Xylitol dehydrogenase (XDH) was purified from the cytoplasmic fraction of Gluconobacter oxydans ATCC 621. The purified enzyme reduced D-xylulose to xylitol in the presence of NADH with an optimum pH of around 5.0...
  24. ncbi Lipase-catalyzed synthesis of xylitol monoesters: solvent engineering approach
    E Castillo
    Departamento de Bioingeniería, Instituto de Biotecnologia, UNAM, Apartado Postal 510 3, Cuernavaca, Morelos 62271, Mexico
    J Biotechnol 102:251-9. 2003
    A solvent engineering strategy was applied to the lipase-catalyzed synthesis of xylitol-oleic acid monoesters. The different esterification degrees for this polyhydroxylated molecule were examined in different organic solvent mixtures...
  25. ncbi A model of xylitol production by the yeast Candida mogii
    Worasit Tochampa
    Department of Biotechnology, Kasetsart University, Bangkok, 10900 Thailand
    Bioprocess Biosyst Eng 28:175-83. 2005
    Production of xylitol from xylose in batch fermentations of Candida mogii ATCC 18364 is discussed in the presence of glucose as the cosubstrate...
  26. ncbi Cloning and expression of a xylitol-4-dehydrogenase gene from Pantoea ananatis
    J S Aarnikunnas
    Division of Microbiology and Epidemiology, Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Appl Environ Microbiol 72:368-77. 2006
    The Pantoea ananatis ATCC 43072 mutant strain is capable of growing with xylitol as the sole carbon source...
  27. ncbi Increase of xylitol productivity by cell-recycle fermentation of Candida tropicalis using submerged membrane bioreactor
    Soun-Gyu Kwon
    Department of Bioscience and Biotechnology, Sejong University, 98 Gunja-Dong, Gwangin-gu, Seoul 143-747, Korea
    J Biosci Bioeng 101:13-8. 2006
    Candida tropicalis, an osmophilic strain isolated from honeycomb, produced xylitol at a maximal volumetric productivity of 3.5 g l(-1) h(-1) from an initial xylose concentration of 200 g l(-1). Even at a very high xylose concentration, e...
  28. ncbi Enhancement of xylitol productivity and yield using a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis under fully aerobic conditions
    Byoung Sam Ko
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon, 305-701, Republic of Korea
    Biotechnol Lett 28:1159-62. 2006
    The effects of glycerol and the oxygen transfer rate on the xylitol production rate by a xylitol dehydrogenase gene (XYL2)-disrupted mutant of Candida tropicalis were investigated...
  29. ncbi Xylitol enhances bacterial killing in the rabbit maxillary sinus
    Christopher L Brown
    Department of Otolaryngology--Head and Neck Surgery, University of Iowa College of Medicine, Iowa City, Iowa 52242-1093, USA
    Laryngoscope 114:2021-4. 2004
    ..b>Xylitol has been shown to effect ASL ionic composition in vitro and to reduce nasal bacterial carriage, otitis media, and ..
  30. ncbi Effect of xylitol on mutans streptococci and lactic acid formation in saliva and plaque from adolescents and young adults with fixed orthodontic appliances
    Christina Stecksén-Blicks
    Department of Odontology, Pediatric Dentistry, Umea University, Umea, Sweden
    Eur J Oral Sci 112:244-8. 2004
    This study aimed to investigate two dose regimens of xylitol-containing tablets on the ecology of dental plaque and saliva during treatment with fixed orthodontic appliances. The study group comprised 56 healthy patients (mean age 15...
  31. ncbi Evaluation of the dental plaque pH recovery effect of a xylitol lozenge on patients with fixed orthodontic appliances
    Abdulkadir Sengun
    Department of Conservative Dentistry, Faculty of Dentistry, Selcuk University, Campus Konya, Turkey
    Angle Orthod 74:240-4. 2004
    The purpose of this study was to evaluate the influence of a xylitol lozenge on the dental plaque pH profile of fixed orthodontic patients. Twelve volunteers participated in this study...
  32. ncbi Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis
    Jung Kul Lee
    BioNgene Co, Ltd, Jongro Ku, Seoul 110 521, Korea
    Appl Environ Microbiol 69:6179-88. 2003
    Xylose reductase (XR) is a key enzyme in D-xylose metabolism, catalyzing the reduction of D-xylose to xylitol. An NADH-preferring XR was purified to homogeneity from Candida parapsilosis KFCC-10875, and the xyl1 gene encoding a 324-amino-..
  33. ncbi Optimization of fed-batch fermentation for xylitol production by Candida tropicalis
    J-H Kim
    Department of Food Science and Technology, Research Center for New Bio-Materials in Agriculture, Seoul National University, Suwon 441-744, South Korea
    J Ind Microbiol Biotechnol 29:16-9. 2002
    b>Xylitol, a functional sweetener, was produced from xylose by biological conversion using Candida tropicalis ATCC 13803...
  34. ncbi Improvement of xylitol production by Candida guilliermondii FTI 20037 previously adapted to rice straw hemicellulosic hydrolysate
    C J Silva
    Department of Biotechnology/FAENQUIL, , Lorena-SP, Brazil
    Lett Appl Microbiol 32:248-52. 2001
    AIMS: To evaluate a simple and economical technique to improve xylitol production using concentrated xylose solutions prepared from rice straw hemicellulosic hydrolysate...
  35. ncbi Effect of chewing gums containing xylitol or probiotic bacteria on salivary mutans streptococci and lactobacilli
    E Caglar
    Department of Paediatric Dentistry, School of Dentistry, Yeditepe University, Bagdat cad 238, Goztepe, 34728 Istanbul, Turkey
    Clin Oral Investig 11:425-9. 2007
    The aim was to evaluate the effect of xylitol and probiotic chewing gums on salivary mutans streptococci (MS) and lactobacilli (LB). The material consisted of 80 healthy young adults (21-24 years) who volunteered after informed consent...
  36. ncbi Difference in the xylitol sensitivity of acid production among Streptococcus mutans strains and the biochemical mechanism
    H Miyasawa-Hori
    Division of Oral Ecology and Biochemistry, Department of Oral Biology, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Oral Microbiol Immunol 21:201-5. 2006
    b>Xylitol inhibits the glycolysis and growth of Streptococcus mutans, but to different degrees among strains. Thus, we studied the biochemical mechanism through which the inhibition varies, using S...
  37. ncbi Influence of maternal xylitol consumption on acquisition of mutans streptococci by infants
    E Soderling
    Institute of Dentistry, University of Turku, Finland
    J Dent Res 79:882-7. 2000
    b>Xylitol is effective as a non-cariogenic sugar substitute. Habitual xylitol consumption appears to select for mutans streptococci (MS) with impaired adhesion properties, i.e., they shed easily to saliva from plaque...
  38. ncbi Thirty-nine-month xylitol chewing-gum programme in initially 8-year-old school children: a feasibility study focusing on mutans streptococci and lactobacilli
    Kauko K Mäkinen
    Institute of Dentistry, University of Turku, Finland
    Int Dent J 58:41-50. 2008
    To investigate the use of xylitol-containing chewing-gums in public elementary schools as a means to affect the growth of salivary and plaque mutans streptococci and salivary lactobacilli.
  39. ncbi Xylitol for messrooms--a method worth trying to prevent caries among seafarers
    U Saarni
    Finnish Student Health Service, Turku, Finland
    Bull Inst Marit Trop Med Gdynia 48:91-7. 1997
    ..A newer method to prevent caries is systematic use of xylitol. Scientific evidence shows that the addition of small quantities of xylitol, a natural carbohydrate sweetener, to ..
  40. ncbi Xylitol gum and maternal transmission of mutans streptococci
    Y Nakai
    Department of Behavioral Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama Shi, Okayama 700 8525, Japan
    J Dent Res 89:56-60. 2010
    ..This study confirmed the effectiveness of maternal early exposure to xylitol chewing gum on mother-child transmission of MS...
  41. ncbi D-xylose metabolism in Hypocrea jecorina: loss of the xylitol dehydrogenase step can be partially compensated for by lad1-encoded L-arabinitol-4-dehydrogenase
    Bernhard Seiboth
    Abteilung für Angewandte Biochemie und Gentechnologie, Institut fur Verfahrenstechnik, Umwelttechnik, und Technische Biowissenschaften, A 1060 Wien, Austria
    Eukaryot Cell 2:867-75. 2003
    ..the D-xylose pathway in Hypocrea jecorina (anamorph: Trichoderma reesei), we cloned the xdh1 gene, encoding NAD-xylitol dehydrogenase, which catalyzes the second step of fungal D-xylose catabolism...
  42. ncbi Heterologous expression, purification, and characterization of a highly active xylose reductase from Neurospora crassa
    Ryan Woodyer
    Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave, Urbana, IL 61801, USA
    Appl Environ Microbiol 71:1642-7. 2005
    ..This enzyme is one of the most active XRs thus far characterized and may be used for the in vitro production of xylitol.
  43. ncbi Xylitol production by Candida tropicalis in a chemically defined medium
    Teak-Bum Kim
    Department of Bioscience and Biotechnology, Sejong University, Seoul 143-747, Republic of Korea
    Biotechnol Lett 25:2085-8. 2003
    ..various vitamins was substituted for a complex medium containing yeast extract (10 g l(-1)) in the production of xylitol by Candida tropicalis...
  44. ncbi The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing
    J Zabner
    Howard Hughes Medical Institute, Departments of Internal Medicine, Pediatrics, and Physiology and Biophysics, and Nuclear Magnetic Resonance Facility, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Proc Natl Acad Sci U S A 97:11614-9. 2000
    ..We found that the five-carbon sugar xylitol has a low transepithelial permeability, is poorly metabolized by several bacteria, and can lower the ASL salt ..
  45. ncbi Xylitol and glycine fillers increase permeability of PMMA to enhance elution of daptomycin
    Alex C McLaren
    Department of Orthopaedic Surgery, University of Arkansas Medical Sciences, Little Rock, AR, USA
    Clin Orthop Relat Res 451:25-8. 2006
    ..We propose xylitol, a naturally occurring sweetener with direct antibiofilm properties, as a filler material...
  46. ncbi Effect of xylitol on growth of Streptococcus pneumoniae in the presence of fructose and sorbitol
    T Tapiainen
    Department of Pediatrics, University of Oulu, Oulu, Finland
    Antimicrob Agents Chemother 45:166-9. 2001
    b>Xylitol is effective in preventing acute otitis media by inhibiting the growth of Streptococcus pneumoniae. To clarify this inhibition we used fructose, which is known to block similar growth inhibition observed in Streptococcus mutans...
  47. ncbi Xylitol concentration in saliva and dental plaque after use of various xylitol-containing products
    P Lif Holgerson
    Department of Odontology, Pediatric Dentistry, Faculty of Medicine, Umea University, Umea, Sweden
    Caries Res 40:393-7. 2006
    The study consisted of two sets of experiments, one in saliva and one in dental plaque. The xylitol concentration in saliva was determined enzymatically in 12 children (mean age 11...
  48. ncbi Hypoglycemia following canine ingestion of xylitol-containing gum
    Eric K Dunayer
    ASPCA Animal Poison Control Center, 1717 S Philo Rd, Suite 36, Urbana, IL 61802, USA
    Vet Hum Toxicol 46:87-8. 2004
    ..collapse, and seizures after consuming a large quantity of sugar-free gum sweetened with the sugar-alcohol xylitol. The dog was treated with i.v...
  49. ncbi Use of xylitol chewing gum in daycare centers: a follow-up study in Savonlinna, Finland
    Helena Kovari
    Savonlinna Health Care Centre, Savonlinna, Finland
    Acta Odontol Scand 61:367-70. 2003
    ..Several field studies have demonstrated a caries-preventive effect of xylitol chewing gum--a measure that could be a practical way of taking care of oral hygiene during daycare hours without ..
  50. ncbi Xylitol and D-arabitol toxicities due to derepressed fructose, galactitol, and sorbitol phosphotransferases of Escherichia coli
    A M Reiner
    J Bacteriol 132:166-73. 1977
    d-Arabitol was observed to be toxic to many laboratory strains of Escherichia coli K-12, and xylitol was found to be toxic to an existing E. coli C mutant strain...
  51. ncbi Ultrastructure of Streptococcus pneumoniae after exposure to xylitol
    Terhi Tapiainen
    Department of Pediatrics, University of Oulu, PO Box 5000, FIN-90014, Oulu
    J Antimicrob Chemother 54:225-8. 2004
    OBJECTIVES: Xylitol is a sugar alcohol which reduces the growth of Streptococcus pneumoniae and the adherence of pneumococci and Haemophilus influenzae to nasopharyngeal cells...
  52. ncbi The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol
    R Bais
    Biochem J 230:53-60. 1985
    ..of the two enzymes was tested to determine the conditions that favour the formation of glycolaldehyde from xylitol. The results indicate that few of these metabolites affect the activity of ketohexokinase, but that aldolase can ..
  53. ncbi Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis
    Su-Ji Han
    Department of Oral Microbiology, School of Dentistry, Pusan National University, Pusan, Korea 602-739
    Clin Diagn Lab Immunol 12:1285-91. 2005
    ..b>Xylitol stands out and is widely believed to possess anticaries properties...
  54. ncbi Morphological changes in Streptococcus mutans after chewing gum containing xylitol for twelve months
    Young Eun Lee
    Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, SamDuk Dong, Daegu 700 412, Republic of Korea
    Curr Microbiol 58:332-7. 2009
    Few studies have been conducted to evaluate the effect of xylitol on the virulence and morphology of Streptococcus mutans (S. mutans). This study was conducted to evaluate changes in the morphology and virulence of S...
  55. ncbi Development of a xylitol biosensor composed of xylitol dehydrogenase and diaphorase
    K Takamizawa
    Department of Bioprocessing, Faculty of Agriculture, Gifu University, Japan
    Can J Microbiol 46:350-7. 2000
    In preparation for the development of a xylitol biosensor, the xylitol dehydrogenase of Candida tropicalis IFO 0618 was partially purified and characterized. The optimal pH and temperature of the xylitol dehydrogenase were pH 8...
  56. ncbi Ion-molecule reactions for the characterization of polyols and polyol mixtures by ESI/FT-ICR mass spectrometry
    Michael A Watkins
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907-2084, and Eli Lilly and Company, Indianapolis, Indiana 46285, USA
    Anal Chem 77:1385-92. 2005
    ..The utility of this method for the analysis of polyols as single-component solutions, as mixtures, or in HPLC effluent (LC-MS analysis) is demonstrated...
  57. ncbi Effect of maternal use of chewing gums containing xylitol, chlorhexidine or fluoride on mutans streptococci colonization in the mothers' infant children
    Ingrid Thorild
    Public Dental Clinic, Varberg, Sweden
    Oral Health Prev Dent 1:53-7. 2003
    PURPOSE: The aim was to evaluate the effect of maternal use of chewing gums containing xylitol, chlorhexidine/xylitol or fluoride on the prevalence of mutans streptococci (MS) in the mothers' 18-month-old offsprings...
  58. ncbi Xylitol candies in caries prevention: results of a field study in Estonian children
    P Alanen
    Institute of Dentistry, University of Turku, Finland
    Community Dent Oral Epidemiol 28:218-24. 2000
    ..reported significant reductions in dental caries occurrence associated with the use of chewing gum containing xylitol. No other xylitol products besides chewing gum have so far been tested in field trials...
  59. ncbi A screening study of xylitol binding in vitro to activated charcoal
    R B Cope
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon 97331, USA
    Vet Hum Toxicol 46:336-7. 2004
    Ingestion of foods containing the sweetener xylitol by dogs results in a significant, and often sustained, insulin-mediated hypoglycemic crisis...
  60. ncbi Maintaining mutans streptococci suppression with xylitol chewing gum
    G H Hildebrandt
    School of Dentistry, University of Minnesota, Minneapolis 55455 0348, USA
    J Am Dent Assoc 131:909-16. 2000
    ..Oral MS levels, however, tend to quickly return to baseline values without further intervention. In this clinical study, the authors evaluated the effect of xylitol chewing gum on MS regrowth.
  61. ncbi Field trial on caries prevention with xylitol candies among disabled school students
    E Honkala
    Faculty of Dentistry, Kuwait University, Safat, Kuwait
    Caries Res 40:508-13. 2006
    ..In a 1999 survey high caries levels were found among physically disabled school students in Kuwait...
  62. ncbi Evaluation of nonglucose carbohydrates in parenteral nutrition for diabetic patients
    M A Valero
    Clinical Nutrition, Hospital Doce de Octubre, Madrid, Spain
    Eur J Clin Nutr 55:1111-6. 2001
    ..patients were randomly divided into two groups receiving either glucose (G), n=71, or glucose-fructose-xylitol 2:1:1 (GFX), n=67...
  63. ncbi Xylitol pediatric topical oral syrup to prevent dental caries: a double-blind randomized clinical trial of efficacy
    Peter Milgrom
    Northwest Center to Reduce Oral Health Disparities, Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195 7475, USA
    Arch Pediatr Adolesc Med 163:601-7. 2009
    To evaluate the effectiveness of a xylitol pediatric topical oral syrup to reduce the incidence of dental caries among very young children and to evaluate the effect of xylitol in reducing acute otitis media in a subsequent study.
  64. ncbi Influence of cultivation conditions on xylose-to-xylitol bioconversion by a new isolate of Debaryomyces hansenii
    Fabio C Sampaio
    Department of Microbiology, Instituto de Biotecnologia Aplicada à Agropecuária, Federal University of Vicosa, Av P H Rolfs s n, 36571 000 Vicosa, Minas Gerais, Brazil
    Bioresour Technol 99:502-8. 2008
    About 270 yeast isolates were screened for xylitol production using xylose as the sole carbon source. The best isolate, Debaryomyces hansenii UFV-170, released 5...
  65. ncbi Xylitol: effects on the acquisition of cariogenic species in infants
    Margherita Fontana
    Microbial Caries Facility, School of Dentistry and Medicine, Indiana University, Indianapolis, USA
    Pediatr Dent 31:257-66. 2009
    The purpose of this study was to examine the effects of xylitol gum (XG) on the acquisition pattern of 39 bacterial species, including mutans streptococci (MS), in infants.
  66. ncbi Chemostat study of xylitol production by Candida guilliermondii
    T Granström
    Helsinki University of Technology, Laboratory of Bioprocess Engineering, Finland
    Appl Microbiol Biotechnol 55:36-42. 2001
    The mechanism of production of xylitol from xylose by Candida guilliermondii was studied using chemostat cultures and enzymatic assays. The maximum dilution rate in aerobic conditions was 0.34 1/h. No xylitol was produced...
  67. ncbi Production of ethanol and xylitol from corn cobs by yeasts
    F Latif
    National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan
    Bioresour Technol 77:57-63. 2001
    ..Maximal xylitol concentration of 21, 20 and 15 g/l from 200 g/l (w/v) dry corn cobs was obtained by C...
  68. ncbi Effect of a xylitol and fluoride containing toothpaste on the remineralization of human enamel in vitro
    Hiroshi Sano
    Product Development Department, International Division, Lion Corporation, Tokyo, Japan
    J Oral Sci 49:67-73. 2007
    The aim of this study was to examine the effect of a fluoride and xylitol containing toothpaste on the remineralization of human enamel using Quantitative Light-induced Fluorescence (QLF)...
  69. ncbi Metabolic engineering of Saccharomyces cerevisiae for conversion of D-glucose to xylitol and other five-carbon sugars and sugar alcohols
    Mervi H Toivari
    VTT Technical Research Centre of Finland, P O Box 1000, FI 02044 VTT, Espoo, Finland
    Appl Environ Microbiol 73:5471-6. 2007
    Recombinant Saccharomyces cerevisiae strains that produce the sugar alcohols xylitol and ribitol and the pentose sugar D-ribose from D-glucose in a single fermentation step are described. A transketolase-deficient S...
  70. ncbi Threshold for transitory diarrhea induced by ingestion of xylitol and lactitol in young male and female adults
    Tsuneyuki Oku
    Graduate School of Human Health Science, Siebold University of Nagasaki, Nagayo, Nagasaki 851 2195, Japan
    J Nutr Sci Vitaminol (Tokyo) 53:13-20. 2007
    ..The objective is to estimate the non-effective dosage that does not cause transitory diarrhea for xylitol, lactitol, and erythritol in healthy subjects...
  71. ncbi Xylitol production from rice straw hemicellulose hydrolyzate by polyacrylic hydrogel thin films with immobilized Candida subtropicalis WF79
    Wen Chang Liaw
    Department of Chemical Engineering, National Yunlin University of Science and Technology, 123, Section 3, University Road, Touliu, Yunlin 640, Taiwan, ROC
    J Biosci Bioeng 105:97-105. 2008
    Xylose from rice straw hemicellulose hydrolysate was fermented for xylitol production using Candida subtropicalis WF79 cells immobilized in polyacrylic hydrogel thin films of 200 mum thickness...
  72. ncbi Xylitol for caries prevention
    John Peldyak
    Institute of Dentistry, University of Turku, Turku, Finland
    J Dent Hyg 76:276-85. 2002
    ..When tested as a sucrose replacer, or even as a small dietary addition, systematic xylitol use leads to impressive reductions in caries incidence...
  73. ncbi Electrochemical reduction of xylose to xylitol by whole cells or crude enzyme of Candida peltata
    Sun Mi Park
    Department of Biological Engineering, Seokyeong University, Seoul 136-704, Republic of Korea
    J Microbiol 43:451-5. 2005
    ..were applied to an electrochemical bioreactor, in order to induce an increment of the reduction of xylose to xylitol. Neutral red was utilized as an electron mediator in the whole cell reactor, and a graphite-Mn(IV) electrode was ..
  74. ncbi Effect of xylitol and sorbitol on plaque acidogenesis
    Christian H Splieth
    Department for Preventive and Pediatric Dentistry, Ernst Moritz Arndt University, Greifswald, Germany
    Quintessence Int 40:279-85. 2009
    To evaluate the in vivo potential of xylitol to reduce plaque acidogenicity in comparison to sorbitol.
  75. ncbi Anticaries efficacy of a sodium monofluorophosphate dentifrice containing xylitol in a dicalcium phosphate dihydrate base. A 30-month caries clinical study in Costa Rica
    Jorge L Sintes
    International Relations and Convention Management, GBD Oral Care, Colgate Palmolive Technology Center, Piscataway, NJ, USA
    Am J Dent 15:215-9. 2002
    ..836% sodium monofluorophosphate (1100 ppm F) in a dicalcium phosphate dihydrate base plus 10% xylitol; and (2) a positive control dentifrice containing 0...
  76. ncbi Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase
    Federico Forneris
    Department of Genetics and Microbiology, University of Pavia, Via Ferrata 1, 27100 Pavia, Italy
    Biochemistry 47:978-85. 2008
    ..in its native state and in complex with both six-carbon (mannitol and sorbitol) and five-carbon substrates (xylitol)...
  77. ncbi Long-term effect of xylitol gum use on mutans streptococci in adults
    S Haresaku
    Department of Preventive and Public Health Dentistry, Oral Public Health, Fukuoka Dental College, Fukuoka, Japan
    Caries Res 41:198-203. 2007
    Many studies have shown the effects of chewing xylitol gum on mutans streptococci (MS) over short- and long-term periods in children; however, few studies have addressed long-term periods in adults...
  78. ncbi Dissolution of xylitol from a food supplement administered with a novel slow-release pacifier: preliminary results
    T Taipale
    Korpilahti Muurame Health Care Center University of Turku, Finland
    Eur Arch Paediatr Dent 8:123-5. 2007
    The aim of the study was to monitor the pattern of release and salivary xylitol concentrations during sucking of a slow-release pacifier used to deliver a novel food supplement.
  79. ncbi Are sugar substitutes also anticariogenic?
    Domenick T Zero
    Department of Preventiuve and Community Dentistry, Indiana University School of Dentistry, 415 Lansing Street, Indianapolis, IN 46202, USA
    J Am Dent Assoc 139:9S-10S. 2008
  80. ncbi Variables that affect xylitol production from sugarcane bagasse hydrolysate in a zeolite fluidized bed reactor
    Julio C Santos
    Departamento de Biotecnologia, Faculdade de Engenharia Quimica de Lorena, Rodovia Itajubá Lorena, Km 74, 5, SP, Brazil
    Biotechnol Prog 21:1639-43. 2005
    The operational conditions for xylitol production by fermentation of sugarcane bagasse hydrolysate in a fluidized bed reactor with cells immobilized on zeolite were evaluated...
  81. ncbi Effect of xylitol/chlorhexidine versus xylitol or chlorhexidine as single rinses on initial biofilm formation of cariogenic streptococci
    Eva Maria Decker
    Department of Conservative Dentistry, School of Dental Medicine, University of Tubingen, Tubingen, Germany
    Quintessence Int 39:17-22. 2008
    ..b>Xylitol, mostly applied via chewing gum, is known to possess favorable plaque-reducing properties...
  82. ncbi Buffering effect of a prophylactic gel on dental plaque in institutionalised elderly
    Anitha Persson
    Department of Odontology, University of Umea, Umea, Sweden
    Gerodontology 24:98-104. 2007
    ..The effect of multiple daily applications of a prophylactic gel, with buffering substances, on plaque acidogenicity in elderly institutionalised individuals was evaluated...
  83. ncbi Fermentation performance of Candida guilliermondii for xylitol production on single and mixed substrate media
    Solange I Mussatto
    Departamento de Biotecnologia, Faculdade de Engenharia Quimica de Lorena, Rodovia Itajubá Lorena, Km 74, 5, Cx Postal 116, Cep 12600 970 Lorena, SP, Brazil
    Appl Microbiol Biotechnol 72:681-6. 2006
    ..glucose, and 9 g l(-1) arabinose) was investigated to evaluate the glucose and arabinose influence on xylose-to-xylitol bioconversion by Candida guilliermondii...
  84. ncbi Effect of phosphate buffer concentration on the batch xylitol production by Candida guilliermondii
    D V Cortez
    Department of Biotechnology, College of Chemical Engineering of Lorena, , Brazil
    Lett Appl Microbiol 42:321-5. 2006
    AIMS: To evaluate the effect of phosphate buffer concentration on growth and xylitol production by Candida guilliermondii FTI 20037...
  85. ncbi Xylitol, sweeteners, and dental caries
    Kiet A Ly
    Department of Dental Public Health Sciences, the Northwest/Alaska Center to Reduce Oral Health Disparities, USA
    Pediatr Dent 28:154-63; discussion 192-8. 2006
    The purpose of this report was to provide an overview of xylitol and other polyol sweeteners and dental caries for clinicians and to discuss current applications for dental practice and potential community-based public health ..
  86. ncbi Influence of a low xylitol-dose on mutans streptococci colonisation and caries development in preschool children
    P Oscarson
    Lycksele Public Dental Clinic, Ume, Sweden
    Eur Arch Paediatr Dent 7:142-7. 2006
    AIM: To evaluate the effect of xylitol-containing tablets on mutans streptococci colonisation and caries development in preschool children. STUDY DESIGN: Randomised single-blind prospective design...
  87. ncbi Caries in 4-year-old children after maternal chewing of gums containing combinations of xylitol, sorbitol, chlorhexidine and fluoride
    I Thorild
    Public Dental Clinic, Varberg
    Eur Arch Paediatr Dent 7:241-5. 2006
    AIM: To evaluate the effect of maternal use of chewing gums containing combinations of xylitol, sorbitol, chlorhexidine and fluoride on caries prevalence in a group of mother's 4-year-old children...
  88. ncbi Screening and characterization of yeasts for xylitol production
    C Guo
    Centre of Microbial Biotechnology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    J Appl Microbiol 101:1096-104. 2006
    AIMS: To discover novel naturally occurring xylitol producing yeast species with potential for industrial applications...
  89. ncbi Preventing dental disease
    Jeffrey P Huston
    American Board of Pediatric Dentistry, USA
    J Calif Dent Assoc 34:491-2. 2006
  90. ncbi Repeated-batch xylitol bioproduction using yeast cells entrapped in polyvinyl alcohol-hydrogel
    M A A Cunha
    Department of Biotechnology, Faculty of Chemical Engineering, Lorena, Rodovia Itajubá Lorena, Km 74 5, C P 116, 12600 970, Lorena SP, Brazil
    Curr Microbiol 54:91-6. 2007
    Xylose-to-xylitol conversion was investigated in a bench-scale bioreactor using Candida guilliermondii cells entrapped within polyvinyl alcohol-hydrogel beads in a system operated in repeated-batch mode with cell recycling...
  91. ncbi Dental plaque formation and salivary mutans streptococci in schoolchildren after use of xylitol-containing chewing gum
    Pernilla Lif Holgerson
    Department of Odontology, Paediatric Dentistry, Faculty of Medicine, Umea University, Umea, Sweden
    Int J Paediatr Dent 17:79-85. 2007
    The aim of this study was to investigate the effect of a fixed daily dose of xylitol on mutans streptococci in saliva and the amount of visible dental plaque...
  92. ncbi A modern paradigm for caries management, part 1: diagnosis and treatment
    Steven Steinberg
    Dent Today 26:134, 136-9; quiz 139. 2007
  93. ncbi The effect of xylitol on Streptococcus mutans in children
    Dominique Massoth
    University of California School of Dentistry, USA
    J Calif Dent Assoc 34:231-4. 2006
    ..was performed on 91 second-grade students from the Los Angeles Unified School District to test the effects of xylitol chewing gum on Streptococcus mutans in the saliva...
  94. ncbi Engineering Escherichia coli for xylitol production from glucose-xylose mixtures
    Patrick C Cirino
    Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Biotechnol Bioeng 95:1167-76. 2006
    The range of value-added chemicals produced by Escherichia coli from simple sugars has been expanded to include xylitol. This was accomplished by screening the in vivo activity of a number of heterologous xylitol-producing enzymes...
  95. ncbi Decreased salivary uptake of [14C]-xylitol after a four-week xylitol chewing gum regimen
    Pernilla Lif Holgerson
    Department of Odontology, Pediatric Dentistry, Faculty of Medicine, Umea University, Sweden
    Oral Health Prev Dent 5:313-9. 2007
    ..were to evaluate a simple method to disclose a microbial shift in saliva and to investigate the short- and long-term effects of daily use of xylitol-containing chewing gums on mutans streptococci (MS) and [14C]-xylitol uptake in saliva.
  96. ncbi Enhanced xylitol production by precultivation of Candida guilliermondii cells in sugarcane bagasse hemicellulosic hydrolysate
    Rita C L B Rodrigues
    Departamento de Biotecnologia, DEBIQ, Faculdade de Engenharia Quimica de Lorena, FAENQUIL, Lorena, SP, Brazil
    Curr Microbiol 53:53-9. 2006
    The present work evaluated the key enzymes involved in xylitol production (xylose reductase [XR] and xylitol dehydrogenase [XDH]) and their correlation with xylose, arabinose, and acetic acid assimilation during cultivation of Candida ..
  97. ncbi Similarity of the effects of erythritol and xylitol on some risk factors of dental caries
    K K Makinen
    Institute of Dentistry, University of Turku, Lemminkaisenkatu 2, FI 20520 Turku, Finland
    Caries Res 39:207-15. 2005
    ..The effects of 6-month use of erythritol (a sugar alcohol of the tetritol type), xylitol (a pentitol) and D-glucitol (sorbitol, a hexitol) were investigated in a cohort of 136 teenage subjects assigned ..
  98. ncbi Mutans streptococci dose response to xylitol chewing gum
    P Milgrom
    Department of Dental Public Health Sciences, Northwest Alaska Center to Reduce Oral Health Disparities, University of Washington, Seattle, WA 98195 USA
    J Dent Res 85:177-81. 2006
    b>Xylitol is promoted in caries-preventive strategies, yet its effective dose range is unclear. This study determined the dose-response of mutans streptococci in plaque and unstimulated saliva to xylitol gum...
  99. ncbi Model compound studies: influence of aeration and hemicellulosic sugars on xylitol production by Candida tropicalis
    T Walthers
    Department of Mechanical Engineering, Technical University of Dresden, Germany
    Appl Biochem Biotechnol 91:423-35. 2001
    ..mannose, and glucose), oxygen limitation, and initial xylose concentration on the fermentation of xylose to xylitol was investigated using experimental design methodology...
  100. ncbi Effect of acetic acid present in bagasse hydrolysate on the activities of xylose reductase and xylitol dehydrogenase in Candida guilliermondii
    Luanne Helena Augusto Lima
    Departamento de Biologia Celular, , 70910-900 Brasilia, DF, Brazil
    Appl Microbiol Biotechnol 65:734-8. 2004
    ..1.1.21) and NAD(P)-dependent xylitol dehydrogenase (XDH) (EC 1.1.1.9), which lead to xylose-->xylitol-->xylulose conversion...
  101. ncbi Metabolic behavior of immobilized Candida guilliermondii cells during batch xylitol production from sugarcane bagasse acid hydrolyzate
    Walter Carvalho
    Department of Biotechnology, Faculty of Chemical Engineering of Lorena, , Km 74.5, Lorena, S.P, Brazil, 12600-000
    Biotechnol Bioeng 79:165-9. 2002
    Candida guilliermondii cells, immobilized in Ca-alginate beads, were used for batch xylitol production from concentrated sugarcane bagasse hydrolyzate. Maximum xylitol concentration (20.6 g/L), volumetric productivity (0.43 g/L...

Research Grants79

  1. Xylitol Adult Caries Trial (X-ACT)--UNC Clinical Center
    Daniel Shugars; Fiscal Year: 2007
    ..The Xylitol for Adult Caries Trial (X-ACT) is a three-year, multi-center, randomized, placebo-controlled, double-blind study ..
  2. Xylitol Adult Caries Trial (X-ACT)--Study Chair application
    James Bader; Fiscal Year: 2007
    ..The Xylitol for Adult Caries Trial (X-ACT) is a three-year, multi-center, randomized, placebo-controlled, double-blind study ..
  3. PREVENT TRANSMIS OF MUTANS STREPTOC FR MOTHER TO CHILD
    Walter Bretz; Fiscal Year: 2004
    ..young infants by an intervention program which may include restorative procedures, topical fluorides, the use of xylitol chewing gum, and chlorhexidine varnishes; 2) to determine whether this intervention reduces or delays the ..
  4. Xylitol Adult Caries Trial (X-ACT): UAB Clinical Center
    GREGG GILBERT; Fiscal Year: 2007
    ..The Xylitol for Adult Caries Trial (X-ACT) is a three-year, multi-center, randomized, placebo-controlled, double-blind study ..
  5. Xylitol Adult Caries Trial (X-ACT) UTHSC San Antonio Clinical Center
    Bennett Amaechi; Fiscal Year: 2007
    ..The Xylitol for Adult Caries Trial (X-ACT) is a three-year, multi-center, randomized, placebo-controlled, double-blind study ..
  6. Identification of anti-cariogenic/low-glycemic activity factors from Lo Han Kuo
    CHIFU HUANG; Fiscal Year: 2006
    ..g. phenylketonurics and diabetics). Moreover, altered sugar alcohol substitute sweeteners, i.e. sorbitol, xylitol, that have been marketed as noncariogenic sweeteners, and more recently as sweeteners for low carbohydrate diets, ..
  7. Xylitol Adult Caries Trial (X-ACT) Data Coordinating Center
    William Vollmer; Fiscal Year: 2007
    ..The Xylitol for Adult Caries Trial (X-ACT) is a three-year, multi-center, randomized, placebo-controlled, double-blind study ..
  8. Structural Basis of Selective Permeability in Aquaporin
    Dax Fu; Fiscal Year: 2006
    ..Aim (2) will determine the structures of GlpF in complex with ribitol and its stereoisomer xylitol to elucidate the structural basis for stereo-selectivity in GlpF. Aim (3) will crystallize AqpZ, an E...
  9. Planning Grant for Xylitol Trial in Caries-Active Adults
    James Bader; Fiscal Year: 2005
    ..The intervention is the daily use of xylitol lozenges...
  10. Fluoride Varnish to Prevent Caries in Toddlers - An Expanded Immunization Program
    Peter Milgrom; Fiscal Year: 2007
    ..Keywords: fluoride varnish, dental caries, oral health, early prevention, multi-center, toddlers. ..
  11. Biotech & Materials Research to Reduce Caries Disparity
    Peter Milgrom; Fiscal Year: 2005
    ..The conference will be co-sponsored by the Northwest/Alaska Center to Reduce Oral Health Disparities, the University of Washington UWeb Bioengineering Center, and the Salivary Diagnostics Project. ..
  12. Aerosolized xylitol for ventilator-associated pneumonia
    Lakshmi Durairaj; Fiscal Year: 2007
    ..The focus of this proposal is to study the effectiveness of a new intervention namely xylitol, a 5-carbon sugar, for the prevention of ventilator-associated pneumonia, a common nosocomial infection among ..
  13. XYLITOL FOR ACUTE OTITIS MEDIA PROPHYLAXIS
    Louis Vernacchio; Fiscal Year: 2003
    ..b>Xylitol, a naturally occurring sugar alcohol, has been proposed as a prophylactic therapy for AOM...
  14. Xylitol Enhancement of Bacterial Killing by Airway
    Joseph Zabner; Fiscal Year: 2003
    ..This could reduce ASL NaCI concentration by substituting the osmotic effect of NaCI with a non-ionic osmolyte. Xylitol is a simple 5-carbon sugar, commonly used as a non-metabolizable sweetener...
  15. Practitioners Engaged in Applied Research and Learning
    Jonathan Ship; Fiscal Year: 2006
    ..In summary, the PEARL Network is uniquely positioned to establish and Maintain a PBRN that will conduct research studies designed to positively impact oral health. ..
  16. Ligand-Receptor Segregation and Airway Remodeling
    Joseph Zabner; Fiscal Year: 2007
    ..We hypothesize that in the asthmatic airways, alterations in the epithelial barrier play a central role in airway epithelial remodeling. ..