blood glucose

Summary

Summary: Glucose in blood.

Top Publications

  1. ncbi Preventive effect of diabegon, a polyherbal preparation, during progression of diabetes induced by high-fructose feeding in rats
    Hariom Yadav
    School of Studies in Biochemistry, Jiwaji University, Gwalior 474011, Madhya Prakesh, India
    J Pharmacol Sci 105:12-21. 2007
  2. ncbi GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide
    Dariush Elahi
    Department of Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    Obesity (Silver Spring) 16:1501-9. 2008
  3. ncbi New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    Josee Dupuis
    Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA
    Nat Genet 42:105-16. 2010
  4. ncbi Cardiovascular morbidity and mortality associated with the metabolic syndrome
    B Isomaa
    Department of Internal Medicine, Jakobstad Hospital, Finland
    Diabetes Care 24:683-9. 2001
  5. ncbi Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
    K Hotta
    Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan
    Arterioscler Thromb Vasc Biol 20:1595-9. 2000
  6. ncbi Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    William C Knowler
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    N Engl J Med 346:393-403. 2002
  7. ncbi Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes
    R Paul Robertson
    Pacific Northwest Research Institute, Seattle, Washington 98122, USA
    J Biol Chem 279:42351-4. 2004
  8. ncbi Follow-up report on the diagnosis of diabetes mellitus
    Saul Genuth
    Diabetes Care 26:3160-7. 2003
  9. ncbi Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
    Samar I Itani
    Diabetes Unit, Section of Endocrinology, Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Diabetes 51:2005-11. 2002
  10. ncbi Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008
    R Phillip Dellinger
    Cooper University Hospital, Camden, NJ, USA
    Crit Care Med 36:296-327. 2008

Research Grants

  1. The effects of glucose on central vagal brainstem circuits
    KIRSTEEN NAIRN BROWNING; Fiscal Year: 2010
  2. Passivating Proteins in Implantable Glucose Sensors
    W Ward; Fiscal Year: 2004
  3. Glucose monitoring using polarized light
    Gerard L Cote; Fiscal Year: 2010
  4. Glucose monitoring using polarized light
    GERARD COTE; Fiscal Year: 2007
  5. Effect of exendin-(9-39) on glucose metabolism in subjects with hyperinsulinism
    DIVA DE LEON; Fiscal Year: 2007
  6. Momentary Biobehavioral Effects on Physical Activity in Adults with T2 Diabetes
    CYNTHIA J FRITSCHI; Fiscal Year: 2010
  7. MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related Gluconeogenesis
    Haiyan Xu; Fiscal Year: 2010
  8. MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related Gluconeogenesis
    Haiyan Xu; Fiscal Year: 2009
  9. MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related Gluconeogenesis
    Haiyan Xu; Fiscal Year: 2010
  10. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William S Harris; Fiscal Year: 2010

Detail Information

Publications262 found, 100 shown here

  1. ncbi Preventive effect of diabegon, a polyherbal preparation, during progression of diabetes induced by high-fructose feeding in rats
    Hariom Yadav
    School of Studies in Biochemistry, Jiwaji University, Gwalior 474011, Madhya Prakesh, India
    J Pharmacol Sci 105:12-21. 2007
    ..Our present results suggest that diabegon may be included in diabetes mellitus treatment regimens, as a drug with good antidiabetic actions but no toxic manifestations...
  2. ncbi GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide
    Dariush Elahi
    Department of Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    Obesity (Silver Spring) 16:1501-9. 2008
    ..We determined whether the insulinomimetic effects of GLP-1 are mediated through its principal metabolite, GLP-1 (9-36) amide (GLP-1m)...
  3. ncbi New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    Josee Dupuis
    Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA
    Nat Genet 42:105-16. 2010
    ....
  4. ncbi Cardiovascular morbidity and mortality associated with the metabolic syndrome
    B Isomaa
    Department of Internal Medicine, Jakobstad Hospital, Finland
    Diabetes Care 24:683-9. 2001
    ..To estimate the prevalence of and the cardiovascular risk associated with the metabolic syndrome using the new definition proposed by the World Health Organization..
  5. ncbi Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
    K Hotta
    Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan
    Arterioscler Thromb Vasc Biol 20:1595-9. 2000
    ..These results suggest that the decreased plasma adiponectin concentrations in diabetes may be an indicator of macroangiopathy...
  6. ncbi Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    William C Knowler
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    N Engl J Med 346:393-403. 2002
    ..9 would have to receive metformin. CONCLUSIONS: Lifestyle changes and treatment with metformin both reduced the incidence of diabetes in persons at high risk. The lifestyle intervention was more effective than metformin...
  7. ncbi Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes
    R Paul Robertson
    Pacific Northwest Research Institute, Seattle, Washington 98122, USA
    J Biol Chem 279:42351-4. 2004
  8. ncbi Follow-up report on the diagnosis of diabetes mellitus
    Saul Genuth
    Diabetes Care 26:3160-7. 2003
  9. ncbi Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
    Samar I Itani
    Diabetes Unit, Section of Endocrinology, Department of Medicine, Boston University Medical Center, Boston, MA, USA
    Diabetes 51:2005-11. 2002
    ..Whether acute FFA-induced insulin resistance in human skeletal muscle is caused by the activation of these specific PKC isoforms and the IKK-beta/IkappaB/NFkappaB pathway remains to be established...
  10. ncbi Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008
    R Phillip Dellinger
    Cooper University Hospital, Camden, NJ, USA
    Crit Care Med 36:296-327. 2008
    ..To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," published in 2004...
  11. ncbi Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
    N Sarwar
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK
    Lancet 375:2215-22. 2010
    ..We aimed to quantify these associations for a wide range of circumstances...
  12. ncbi Fasting serum glucose level and cancer risk in Korean men and women
    Sun Ha Jee
    Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea
    JAMA 293:194-202. 2005
    ..Diabetes is a serious and costly disease that is becoming increasingly common in many countries. The role of diabetes as a cancer risk factor remains unclear...
  13. ncbi Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    A M Shapiro
    Surgical Medical Research Institute and the Department of Surgery, University of Alberta, Edmonton, Canada
    N Engl J Med 343:230-8. 2000
    ..Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that only 8 percent are free of the need for insulin therapy at one year...
  14. ncbi Relationship between blood glucose and carotid intima media thickness: A meta-analysis
    Thomas R Einarson
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
    Cardiovasc Diabetol 9:37. 2010
    ..The link has not been established between glucose and CIMT; therefore, we sought to assess the relationship between glucose and CIMT...
  15. ncbi Evaluating the glucose tolerance test in mice
    Sofianos Andrikopoulos
    Univ of Melbourne, Dept of Medicine, Heidelberg Heights, Victoria, Australia
    Am J Physiol Endocrinol Metab 295:E1323-32. 2008
    ..We conclude that 2 g/kg glucose administered orally following 6 h of fasting is best to assess glucose tolerance in mice under these conditions...
  16. ncbi Systematic review: glucose control and cardiovascular disease in type 2 diabetes
    Tanika N Kelly
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2000, New Orleans, LA 70112, USA
    Ann Intern Med 151:394-403. 2009
    ..Results from clinical trials examining the effect of intensive glucose control on cardiovascular disease have been conflicting...
  17. ncbi The natural history of nonalcoholic fatty liver disease: a population-based cohort study
    Leon A Adams
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Gastroenterology 129:113-21. 2005
    ..Liver-related death is a leading cause of mortality, although the absolute risk is low...
  18. ncbi Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat
    Doris A Stoffers
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Clinical Research Building 611B, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA
    Diabetes 52:734-40. 2003
    ..These results indicate that exposure to Ex-4 in the newborn period reverses the adverse consequences of fetal programming and prevents the development of diabetes in adulthood...
  19. ncbi Intensive glucose control and macrovascular outcomes in type 2 diabetes
    F M Turnbull
    The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
    Diabetologia 52:2288-98. 2009
    ..The aim of these analyses was to generate more precise estimates of the effects of more-intensive, compared with less-intensive, glucose control on the risk of major cardiovascular events amongst patients with type 2 diabetes...
  20. ncbi Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006
    Bernard M Y Cheung
    Department of Clinical Pharmacology, School of Clinical and Experimental Medicine, University of Birmingham, United Kingdom
    Am J Med 122:443-53. 2009
    ..Changes in the prevalence, treatment, and management of diabetes in the United States from 1999 to 2006 were studied using data from the National Health and Nutrition Examination Survey...
  21. ncbi Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus
    David B Sacks
    Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Thorn 530, 75 Francis St, Boston, MA 02115, USA
    Clin Chem 48:436-72. 2002
    ..Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially...
  22. ncbi Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
    Jing Xu
    Department of Metabolic Disorders, Amgen, Thousand Oaks, California, USA
    Diabetes 58:250-9. 2009
    ..The aims of the current study are to evaluate the role of FGF21 in energy metabolism and to provide mechanistic insights into its glucose and lipid-lowering effects in a high-fat diet-induced obesity (DIO) model...
  23. ncbi The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes
    Francesco Rubino
    IRCAD European Institute of Telesurgery, University Louis Pasteur, Strasbourg, France
    Ann Surg 244:741-9. 2006
    ..We sought to distinguish between these two mechanisms...
  24. ncbi Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways
    Nicole Soranzo
    Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U K
    Diabetes 59:3229-39. 2010
    ..We aimed to identify such genetic factors and investigate the extent to which they influence diabetes classification based on HbA₁(c) levels...
  25. ncbi Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
    Faramarz Ismail-Beigi
    Department of Medicine, Division of Clinical and Molecular Endocrinology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106 4951, USA
    Lancet 376:419-30. 2010
    ..We investigated whether reduction of blood glucose concentration decreases the rate of microvascular complications in people with type 2 diabetes.
  26. ncbi Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content
    Balasubramanian Ravikumar
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U K
    Diabetes 57:2288-95. 2008
    ..We studied the effect of pioglitazone on hepatic triglyceride content and the consequent effect on postprandial endogenous glucose production (EGP) in type 2 diabetes...
  27. ncbi Endosperm and whole grain rye breads are characterized by low post-prandial insulin response and a beneficial blood glucose profile
    Liza A H Rosén
    Division of Applied Nutrition and Food Chemistry, Department of Food Technology, Engineering and Nutrition, Lund University, Lund, Sweden
    Nutr J 8:42. 2009
    ..The objective of this study was to explore the mechanism for a reduced post-prandial insulin demand with rye products...
  28. ncbi Effect of treatment of gestational diabetes mellitus on pregnancy outcomes
    Caroline A Crowther
    Department of Obstetrics and Gynaecology, University of Adelaide, Adelaide, Australia
    N Engl J Med 352:2477-86. 2005
    ..assigned women between 24 and 34 weeks' gestation who had gestational diabetes to receive dietary advice, blood glucose monitoring, and insulin therapy as needed (the intervention group) or routine care...
  29. ncbi Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle
    Michale Bouskila
    Am J Physiol Endocrinol Metab 294:E28-35. 2008
    ..This suggests that allosteric regulation of GS by G-6-P may play a key role in insulin-stimulated muscle glycogen synthesis in vivo...
  30. ncbi Objectively measured light-intensity physical activity is independently associated with 2-h plasma glucose
    Genevieve N Healy
    Cancer Prevention Research Centre, School of Population Health, The University of Queensland, Brisbane, Australia
    Diabetes Care 30:1384-9. 2007
    ..We examined the associations of objectively measured sedentary time, light-intensity physical activity, and moderate- to vigorous-intensity activity with fasting and 2-h postchallenge plasma glucose in Australian adults...
  31. ncbi Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice
    Hayato Maeda
    Faculty of Fisheries Sciences, Hokkaido University, 3 1 1 Minato, Hakodate, Hokkaido 041 8611, Japan
    J Agric Food Chem 55:7701-6. 2007
    ..and antidiabetic effects of fucoxanthin and fish oil, we investigated the effect on the WAT weight, blood glucose, and insulin levels of KK- A(y) mice...
  32. ncbi Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population
    Yong Ho Lee
    Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon dong Seodaemun gu, Seoul 120 752, South Korea
    J Hum Genet 53:991-8. 2008
    ..In conclusion, we have shown that SNPs in HHEX, CDKN2A/B, CDKAL1, KCNQ1 and SLC30A8 confer a risk of T2DM in the Korean population...
  33. ncbi Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults
    Elizabeth Selvin
    Department of Epidemiology and the Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA
    N Engl J Med 362:800-11. 2010
    ..Fasting glucose is the standard measure used to diagnose diabetes in the United States. Recently, glycated hemoglobin was also recommended for this purpose...
  34. ncbi Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice
    Masahito Takikawa
    College of Bioscience and Biotechnology, Chubu University, Kasugai, Aichi 487 8501, Japan
    J Nutr 140:527-33. 2010
    ..Dietary BBE significantly reduced the blood glucose concentration and enhanced insulin sensitivity...
  35. ncbi Effect of a low-glycemic index or a high-cereal fiber diet on type 2 diabetes: a randomized trial
    David J A Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
    JAMA 300:2742-53. 2008
    ..Low-glycemic index diets may improve both glycemic control and cardiovascular risk factors for patients with type 2 diabetes but debate over their effectiveness continues due to trial limitations...
  36. ncbi A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women
    S Liu
    Departments of Epidemiology and Nutrition, The Harvard School of Public Health, Boston, MA 02215, USA
    Am J Clin Nutr 71:1455-61. 2000
    ..Little is known about the effects of the amount and type of carbohydrates on risk of coronary heart disease (CHD)...
  37. ncbi Increased arterial stiffness in healthy subjects with high-normal glucose levels and in subjects with pre-diabetes
    Jin Young Shin
    Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
    Cardiovasc Diabetol 10:30. 2011
    ..The purpose of this study is to investigate the relationship between FPG and arterial stiffness in non-diabetic healthy subjects...
  38. ncbi National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
    Goodarz Danaei
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Lancet 378:31-40. 2011
    ..We estimated trends and their uncertainties in mean fasting plasma glucose (FPG) and diabetes prevalence for adults aged 25 years and older in 199 countries and territories...
  39. ncbi Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease
    Emmanuel Planel
    Laboratory for Alzheimer's Disease, The Institute of Physical and Chemical Research, Wako-shi, Saitama 351-0198, Japan
    J Neurosci 24:2401-11. 2004
    ..Our results imply that serine-threonine protein phosphatase 2A plays a major role in regulating tau phosphorylation in the adult brain and provide in vivo evidence for its crucial role in abnormal tau hyperphosphorylation in AD...
  40. ncbi Serum C-reactive protein level and prediabetes in two Asian populations
    C Sabanayagam
    Department of Community Medicine, West Virginia University School of Medicine, PO Box 9190, Morgantown, WV 26506 9190, USA
    Diabetologia 54:767-75. 2011
    ..C-reactive protein (CRP), a marker of inflammation, is associated with diabetes and CVD. However, studies examining the association between CRP and prediabetes among participants without diabetes are limited...
  41. ncbi Diagnosing insulin resistance in the general population
    K A McAuley
    Department of Human Nutrition, Otago University, Dunedin, New Zealand
    Diabetes Care 24:460-4. 2001
    ....
  42. ncbi Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training
    B F Vind
    Diabetes Research Center, Department of Endocrinology, Odense University Hospital, Denmark
    Diabetologia 54:157-67. 2011
    ..In this study, we examined insulin action on site-specific phosphorylation of TBC1D4 and the effect of exercise training on insulin action and signalling to TBC1D4 in skeletal muscle from type 2 diabetic patients...
  43. ncbi Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians
    John C Chambers
    Department of Epidemiology and Public Health, Imperial College London, London, U K
    Diabetes 58:2703-8. 2009
    ..Fasting plasma glucose and risk of type 2 diabetes are higher among Indian Asians than among European and North American Caucasians. Few studies have investigated genetic factors influencing glucose metabolism among Indian Asians...
  44. ncbi Description of outcomes of experimental infection with feline haemoplasmas: copy numbers, haematology, Coombs' testing and blood glucose concentrations
    Severine Tasker
    School of Clinical Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU, United Kingdom
    Vet Microbiol 139:323-32. 2009
    ..to 85 days post-infection (DPI) for haemoplasma real-time quantitative PCR, haematology, Coombs' testing and blood glucose measurement...
  45. ncbi Emerging cardiovascular actions of the incretin hormone glucagon-like peptide-1: potential therapeutic benefits beyond glycaemic control?
    David J Grieve
    Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen s University Belfast, UK
    Br J Pharmacol 157:1340-51. 2009
    ..This review will discuss the current understanding of GLP-1 biology, examine its emerging cardiovascular actions in both health and disease and explore the potential use of GLP-1 as a novel treatment for CVD...
  46. ncbi Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression
    Hao Zhang
    Department of Pharmacology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing 100050, China
    Metabolism 59:285-92. 2010
    ..In the clinical study, BBR significantly lowered fasting blood glucose (FBG), hemoglobin A(1c), triglyceride, and insulin levels in patients with type 2 diabetes mellitus (T2DM)...
  47. ncbi International trial of the Edmonton protocol for islet transplantation
    A M James Shapiro
    Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada
    N Engl J Med 355:1318-30. 2006
    ..We conducted an international, multicenter trial to explore the feasibility and reproducibility of islet transplantation with the use of a single common protocol (the Edmonton protocol)...
  48. ncbi Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy
    Heather D VanGuilder
    Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
    PLoS ONE 6:e16271. 2011
    ....
  49. ncbi Physical exercise for the prevention and treatment of type 2 diabetes
    C Sanz
    Department of Diabetology, Metabolic Diseases and Nutrition, CHU de Toulouse, 31073 Toulouse, France
    Diabetes Metab 36:346-51. 2010
    ..studies have confirmed that physical training based on endurance and/or resistance exercises can also improve blood glucose control in type 2 diabetics with a mean glycated haemoglobin decrease of 0.6%...
  50. ncbi Clinical risk factors, DNA variants, and the development of type 2 diabetes
    Valeriya Lyssenko
    Department of Clinical Sciences, Lund University, Malmo, Sweden
    N Engl J Med 359:2220-32. 2008
    ..Type 2 diabetes mellitus is thought to develop from an interaction between environmental and genetic factors. We examined whether clinical or genetic factors or both could predict progression to diabetes in two prospective cohorts...
  51. ncbi Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes
    Eric J Rulifson
    Department of Developmental Biology, Beckman Center B300, Stanford University, Stanford, CA 94305 5329, USA
    Science 296:1118-20. 2002
    ..Interestingly, the phenotype of flies lacking IPCs includes certain features of diabetes mellitus...
  52. ncbi Insulin-S.O (sodium oleate) complex-loaded PLGA nanoparticles: formulation, characterization and in vivo evaluation
    Shaoping Sun
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, PR China
    J Microencapsul 27:471-8. 2010
    ..The results showed that the use of Ins-S.O complex-loaded PLGA nanoparticles is an effective method of reducing plasma glucose levels. The insulin nanoparticles also improved the glycaemic response to an oral glucose challenge...
  53. ncbi Berberine inhibits adipogenesis in high-fat diet-induced obesity mice
    Yueshan Hu
    Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
    Fitoterapia 81:358-66. 2010
    ..Berberine had no adverse effects on ND mice. These encouraging findings suggest that berberine has excellent pharmacological potential to prevent obesity...
  54. ncbi Severe hypoglycemia and risks of vascular events and death
    Sophia Zoungas
    George Institute for International Health, University of Sydney, Sydney, Australia
    N Engl J Med 363:1410-8. 2010
    ..We analyzed data from a large study of intensive glucose lowering to explore the relationship between severe hypoglycemia and adverse clinical outcomes...
  55. ncbi Vitamin D status is modestly associated with glycemia and indicators of lipid metabolism in French-Canadian children and adolescents
    Edgard E Delvin
    Department of Clinical Biochemistry, CHU Sainte Justine, Montreal, Canada
    J Nutr 140:987-91. 2010
    ..Although the observed associations between 25(OH)D concentrations and fasting glucose, and variables of lipid metabolism are modest, they may have a potential long-term impact on cardiovascular risk...
  56. ncbi Preventive effects of fenofibrate on insulin resistance, hyperglycaemia, visceral fat accumulation in NIH mice induced by small-dose streptozotocin and lard
    Weidong Xie
    Life Sciences Division, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China
    Pharmacol Res 55:392-9. 2007
    ..In the future study, we should investigate if higher dosage of vitamin C or other antioxidants would enhance preventive effects of fenofibrate in type 2 diabetes...
  57. ncbi Persistent hyperglycemia is predictive of outcome in critically ill trauma patients
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center, Baltimore, MD 21201, USA
    J Trauma 58:921-4. 2005
    ..Our objectives were to determine whether persistent hyperglycemia was predictive of outcome in critically ill trauma patients...
  58. ncbi Effect of cereal test breakfasts differing in glycemic index and content of indigestible carbohydrates on daylong glucose tolerance in healthy subjects
    Anne C Nilsson
    Division of Applied Nutrition and Food Chemistry, Department of Food Technology, Engineering and Nutrition, Lund University, Sweden
    Am J Clin Nutr 87:645-54. 2008
    ..Frequent hyperglycemic episodes are increasingly being associated with an increased risk of type 2 diabetes and cardiovascular disease...
  59. ncbi Amylin and its relation to insulin and lipids in obese children before and after weight loss
    Thomas Reinehr
    Vestische Hospital for Children and Adolescents Datteln, University of Witten Herdecke, Dr F Steiner Str 5, 45711 Datteln, Germany
    Obesity (Silver Spring) 15:2006-11. 2007
    ..There are limited data concerning the relationships between amylin, weight status, lipids, insulin, and insulin resistance in obese humans. Therefore, the aim was to study these relationships in cross-sectional and longitudinal analyses...
  60. ncbi Prevalence of metabolic syndrome in obese Turkish children and adolescents
    Mehmet Emre Atabek
    Department of Pediatric Endocrinology and Diabetes, Selcuk University, School of Medicine, Konya, Turkey
    Diabetes Res Clin Pract 72:315-21. 2006
    ..The aim of our study was to assess the prevalence of metabolic syndrome and the other metabolic features in obese children...
  61. ncbi Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians
    Steven J R Meex
    Cardiovascular Research Institute Maastricht, Department of Internal Medicine, University of Maastricht, 6200 MD Maastricht, The Netherlands
    J Clin Endocrinol Metab 92:2720-5. 2007
    ..Activating transcription factor 6 (ATF6) is critical for initiation and full activation of the unfolded protein response. An association between genetic variation in ATF6 and type 2 diabetes (DM2) was recently reported in Pima Indians...
  62. ncbi Improved glycemic control and lipid profile and normalized fibrinolytic activity on a low-glycemic index diet in type 2 diabetic patients
    A E Järvi
    Clinical Nutrition Research Unit, Uppsala University, Sweden
    Diabetes Care 22:10-8. 1999
    ..To evaluate the effects of varying the glycemic index (GI) of carbohydrate-rich foods on metabolic control in type 2 diabetic patients...
  63. ncbi Effects of propolis on blood glucose, blood lipid and free radicals in rats with diabetes mellitus
    H U Fuliang
    College of Animal Science, Zhejiang University, Hangzhou 310029, China
    Pharmacol Res 51:147-52. 2005
    The effects of ethanol (EEP) and water (WSD) extracts of propolis collected from north China on blood glucose, blood lipid and free radicals in rats with diabetes mellitus were studied...
  64. ncbi Plasma visfatin concentrations and fat depot-specific mRNA expression in humans
    Janin Berndt
    University of Leipzig, D 04103 Leipzig, Germany
    Diabetes 54:2911-6. 2005
    ..In addition, we did not find differences in visfatin mRNA expression between visceral and subcutaneous adipose tissue in humans...
  65. ncbi The influence of the glycaemic index of breakfast and lunch on substrate utilisation during the postprandial periods and subsequent exercise
    Emma Stevenson
    Sport and Exercise Nutrition Research Group, School of Sport and Exercise Sciences, Loughborough University, Loughborough, Leicestershire, LE11 3TU, UK
    Br J Nutr 93:885-93. 2005
    ..Furthermore, during subsequent exercise, plasma glucose concentrations were better maintained following the LGI CHO meals...
  66. ncbi Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men
    Nelly Pitteloud
    Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Diabetes Care 28:1636-42. 2005
    ....
  67. ncbi The relationship between thyrotropin and low density lipoprotein cholesterol is modified by insulin sensitivity in healthy euthyroid subjects
    S J Bakker
    Department of Internal Medicine, University Hospital Groningen, 9700 RB Groningen
    J Clin Endocrinol Metab 86:1206-11. 2001
    ..Importantly, the effect-modification of the association of TSH with LDL-C by insulin sensitivity suggests that insulin-resistant subjects are most susceptible to this increased risk...
  68. ncbi Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    J C Yoon
    Dana Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 413:131-8. 2001
    b>Blood glucose levels are maintained by the balance between glucose uptake by peripheral tissues and glucose secretion by the liver. Gluconeogenesis is strongly stimulated during fasting and is aberrantly activated in diabetes mellitus...
  69. ncbi Non-high-density-lipoprotein cholesterol and cardiovascular risk factors among adolescents with and without impaired fasting glucose
    Jian Liu
    Department of Community Health Sciences, Brock University, St Catharines, ON L2S3A1, Canada
    Appl Physiol Nutr Metab 34:136-42. 2009
    ..Thus, the levels of non-HDL cholesterol may be an important indicator in monitoring cardiovascular disease risk among adolescents with IFG...
  70. ncbi Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats
    J Cacho
    Facultades de Farmacia y Medicina, Universidad CEU Centro de Estudios Universitarios San Pablo, Madrid, Spain
    Am J Physiol Endocrinol Metab 295:E1269-76. 2008
    ..Together, our data demonstrate that these indexes provide an easy and accurate measure of insulin sensitivity during pregnancy in the rat...
  71. ncbi Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    Loredana Farilla
    Cedars-Sinai Medical Center, Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Los Angeles, California 90048, USA
    Endocrinology 143:4397-408. 2002
    ..Our findings provide evidence that the beneficial effects of GLP-1 in Zucker diabetic rats is mediated by an increase in islet cell proliferation and a decrease of cellular apoptosis...
  72. ncbi Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet
    Jamie W Joseph
    Department of Medicine, University of Toronto, Ontario, Canada
    Diabetes 51:3211-9. 2002
    ..HFD-fed UCP2 (-/-) mice have lower fasting blood glucose and elevated insulin levels when compared with wild-type (WT) mice...
  73. ncbi Fish oil and argan oil intake differently modulate insulin resistance and glucose intolerance in a rat model of dietary-induced obesity
    Samira Samane
    Department of Pharmacology, Universite de Montreal, Montreal, Quebec, Canada
    Metabolism 58:909-19. 2009
    ..Our data also show for the first time that AO can improve some of the metabolic and insulin signaling abnormalities associated with HFHS feeding...
  74. ncbi Improvement in glucose tolerance as a result of enhanced insulin sensitivity during electroacupuncture in spontaneously diabetic Goto-Kakizaki rats
    Naoto Ishizaki
    Division of Acupuncture for Visceral Functions, Department of Clinical Acupuncture and Moxibustion, Meiji University of Integrative Medicine, Hiyoshi cho, Nantan shi, Kyoto 629 0392, Japan
    Metabolism 58:1372-8. 2009
    ..A significant decrease in fasting blood glucose and an increase in plasma insulin levels were observed during the fasting period in GK rats treated with EA...
  75. ncbi Dietary glycemic index: health implications
    Jennie Brand-Miller
    Human Nutrition Unit, University of Sydney, NSW 2006, Australia
    J Am Coll Nutr 28:446S-449S. 2009
    ..Although lower carbohydrate, higher protein diets increase the rate of weight loss, cohort studies and meta-analyses of clinical trials suggest the potential for increased mortality...
  76. ncbi Are metabolic indices different between drug-naïve first-episode psychosis patients and healthy controls?
    Sarojini Sengupta
    Douglas Mental Health University Institute, Louis H Lafontaine Hospital, Montreal, Canada
    Schizophr Res 102:329-36. 2008
    ..To compare glucose and lipid metabolism parameters between drug-naïve first-episode psychosis (FEP) patients with a diagnosis of schizophrenia spectrum disorder and healthy controls matched for age, ethnicity, and gender...
  77. ncbi Thiazolidinediones increase hepatic insulin extraction in African Americans with impaired glucose tolerance and type 2 diabetes mellitus. A pilot study of rosiglitazone
    Kwame Osei
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, The Ohio State University College of Medicine and Public Health, Columbus, OH 43210, USA
    Metabolism 56:24-9. 2007
    ..The significance of the increased insulin clearance by TZD therapy remains uncertain and deserves further investigation in patients with insulin resistance and glucose intolerance...
  78. ncbi A randomized, double-blind, placebo-controlled trial of metformin treatment of weight gain associated with initiation of atypical antipsychotic therapy in children and adolescents
    David J Klein
    Division of Endocrinology, Cincinnati Children s Hospital Medical Center, ML 7012, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Am J Psychiatry 163:2072-9. 2006
    ..Second-generation, or atypical, antipsychotics effectively treat psychiatric illness in children and adolescents. However, weight gain and abnormalities in insulin sensitivity, including diabetes, complicate this therapy...
  79. ncbi Haemoglobin A1c is not a surrogate for glucose and insulin measures for investigating the early life and childhood determinants of insulin resistance and Type 2 diabetes in healthy children. An analysis from the Avon Longitudinal Study of Parents and Chil
    W A Shultis
    Department of Social Medicine, University of Bristol, UK
    Diabet Med 23:1357-63. 2006
    ..We investigated haemoglobin A(1c) (HbA(1c)), a marker of glycaemia measured in non-fasting blood, as an alternative...
  80. ncbi Dietary red chilli (Capsicum frutescens L.) is insulinotropic rather than hypoglycemic in type 2 diabetes model of rats
    Md Shahidul Islam
    Department of Food and Nutrition, Seoul National University, Seoul 151 742, South Korea
    Phytother Res 22:1025-9. 2008
    ..After 4 weeks feeding of experimental diets, the fasting blood glucose concentrations in both RC fed groups were not significantly different...
  81. ncbi Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model
    Michela Novelli
    Dipartimento di Patologia Sperimentale, University of Pisa, Pisa, Italy
    Pancreas 35:e10-7. 2007
    ....
  82. ncbi Improvement of glycemic control after a 3-5 day insulin infusion in type 2-diabetic patients with insulin resistance can be maintained with glitazone therapy
    Georg Biesenbach
    2nd Department of Internal Medicine, Hospital Linz, Linz, Austria
    Wien Klin Wochenschr 118:543-8. 2006
    ....
  83. ncbi Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats
    Meng Kwoon Sim
    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Endocrinology 148:5925-32. 2007
    ..d for 4 and 6 wk, respectively. Control diabetic animals were similarly administered water. Blood glucose of each animal was determined fortnightly by oral glucose tolerance test and blood insulin on the last day of ..
  84. ncbi Antidiabetic zinc(II)-N-acetyl-L-cysteine complex: evaluations of in vitro insulinomimetic and in vivo blood glucose-lowering activities
    Yusuke Adachi
    Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan
    Biofactors 29:213-23. 2007
    ..Recently, we found that Zn(II) complexes have in vitro insulinomimetic and in vivo blood glucose-lowering activities...
  85. ncbi Is Ramadan fasting safe in type 2 diabetic patients in view of the lack of significant effect of fasting on clinical and biochemical parameters, blood pressure, and glycemic control?
    M M'guil
    UFR Physiologie Pharmacologie, Faculte des Sciences, Fes, Morocco
    Clin Exp Hypertens 30:339-57. 2008
    ..With a regimen adjustment of OHD, diet control, and physical activity, most patients with T2D whose diabetes was well-controlled before Ramadan can safely observe Ramadan fasting...
  86. ncbi Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats
    Chan Sik Kim
    Department of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine, 461 24 Jeonmin dong, Yuseong Gu, Daejeon 305 811, Republic of Korea
    J Ethnopharmacol 111:240-7. 2007
    ..001), PKC protein (p<0.01), TGF-beta mRNA (p<0.05) and VEGF mRNA (p<0.05). Thus, based on our finding, KIOM-79 could reduce the hyperglycemia, and prevent or retard the development of diabetic nephropathy...
  87. ncbi Phylloquinone intake, insulin sensitivity, and glycemic status in men and women
    Makiko Yoshida
    Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 88:210-5. 2008
    ..Limited evidence suggests that vitamin K may have a beneficial role in glucose homeostasis. No observational data exist on the associations between vitamin K intake and insulin sensitivity...
  88. ncbi Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats
    Md Shahidul Islam
    Department of Food and Nutrition, Seoul National University, Seoul, Republic of Korea
    J Med Food 11:152-9. 2008
    ..Final body weight, fasting blood glucose, blood glycated hemoglobin, liver weight, liver glycogen levels, and serum lipid profiles were not influenced ..
  89. ncbi Effect of Withania somnifera on insulin sensitivity in non-insulin-dependent diabetes mellitus rats
    Tarique Anwer
    Department of Pharmacology, Faculty of Pharmacy, Jamia Hamdard, Hamdard University, New Delhi, India
    Basic Clin Pharmacol Toxicol 102:498-503. 2008
    ..A significant increase in blood glucose, glycosylated haemoglobin (HbA(1)c) and serum insulin levels were observed in NIDDM control rats...
  90. ncbi Diabetes. Paradoxical effects of tightly controlled blood sugar
    Gary Taubes
    Science 322:365-7. 2008
  91. ncbi Beneficial effects of insulin on glycemic control and beta-cell function in newly diagnosed type 2 diabetes with severe hyperglycemia after short-term intensive insulin therapy
    Harn Shen Chen
    Department of Medicine, Division of Endocrinology and Metabolism, Taipei Veterans General Hospital, Taipei, Taiwan
    Diabetes Care 31:1927-32. 2008
    ..To evaluate whether treatment with insulin is advantageous compared with oral antidiabetes agents in newly diagnosed type 2 diabetes with severe hyperglycemia after short-term intensive insulin therapy...
  92. ncbi Effect of pioglitazone on the metabolic and hormonal response to a mixed meal in type II diabetes
    A Gastaldelli
    Metabolism Unit, CNR Institute of Clinical Physiology, University of Pisa School of Medicine, Pisa, Italy
    Clin Pharmacol Ther 81:205-12. 2007
    ..In mild-to-moderate T2D, pioglitazone monotherapy decreased fasting and post-prandial glycemia, principally via inhibition of gluconeogenesis, improved hepatic and peripheral insulin resistance...
  93. ncbi Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes
    Antonio Cervera
    Division of Diabetes, Department of Medicine, University of Texas Health Science Center, San Antonio, TX, USA
    Am J Physiol Endocrinol Metab 294:E846-52. 2008
    ..CON). Acetaminophen((AUC)) was reduced by approximately 80% in EXE vs. CON (P < 0.01). We conclude that exenatide infusion attenuates postprandial hyperglycemia by decreasing EGP (by approximately 50%) and by slowing gastric emptying...
  94. ncbi Intermediate postchallenge hyperglycemia in overweight and obese subjects: a new marker of impaired glucose regulation?
    Emmanuel J Diamantopoulos
    4th Department of Internal Medicine, Evangelismos State General Hospital, Athens, Greece
    Angiology 57:709-16. 2006
    ..Therefore, evaluating intermediate glucose levels in an OGTT could contribute to better identify overweight individuals at risk of developing diabetes mellitus and cardiovascular events...
  95. ncbi Effect of periodontitis on insulin resistance and the onset of type 2 diabetes mellitus in Zucker diabetic fatty rats
    Keiko Watanabe
    Department of Periodontics, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612 5176, USA
    J Periodontol 79:1208-16. 2008
    ..The purpose of this study was to determine the causal effect of periodontitis and the concomitant impact of diet on the onset of insulin resistance (IR) and T2DM using a rat model system that simulates human obesity and T2DM...
  96. ncbi Effects of S 15511, a therapeutic metabolite of the insulin-sensitizing agent S 15261, in the Zucker Diabetic Fatty rat
    L C Pickavance
    Department of Veterinary Preclinical Sciences, University of Liverpool, Liverpool, UK
    Diabetes Obes Metab 9:114-20. 2007
    ..The study was designed to determine the biological activity of its two major metabolites, S 15511 and Y 415, and whether or not they have an additive effect...
  97. ncbi Effects of pioglitazone vs glibenclamide on postprandial increases in glucose and triglyceride levels and on oxidative stress in Japanese patients with type 2 diabetes
    Yutaka Mori
    Department of Internal Medicine, National Hospital Organization, Utsunomiya National Hospital, Kawachi, Tochigi, Japan
    Endocrine 29:143-8. 2006
    ..Our study results suggest that PG suppresses increases in postprandial glucose and TG levels, and improves insulin resistance; and, in addition, that PG may have a favorable impact on oxidative stress in type 2 diabetic patients...
  98. ncbi Oral therapies for diabetic hyperglycemia
    H E Lebovitz
    Department of Medicine, State University of New York Health Science Center at Brooklyn, Brooklyn, New York, USA
    Endocrinol Metab Clin North Am 30:909-33. 2001
    ..In choosing combinations of oral antihyperglycemic agents, their effects on the components treatment of type 2 diabetic patients. These classes improve glucose considered, as must the specific effects of the agents on glucose metabolism...
  99. ncbi [Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes]
    M Hanefeld
    , GWT-TU Dresden mbH
    MMW Fortschr Med 145:30-4. 2003
    ..rarely suffices to correct the complex dysregulation, when close-to normalization of the glucose triad fasting blood glucose, postprandial blood glucose and HbA1C fails, early application of complementary combinations offer advantages, ..
  100. ncbi Effect of pioglitazone compared with metformin on glycemic control and indicators of insulin sensitivity in recently diagnosed patients with type 2 diabetes
    Imre Pavo
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46201, USA
    J Clin Endocrinol Metab 88:1637-45. 2003
    ....
  101. ncbi Leptin levels in type 2 diabetes: associations with measures of insulin resistance and insulin secretion
    M Wauters
    Department of Diabetology, Metabolism and Clinical Nutrition, University Hospital Antwerp, Belgium
    Horm Metab Res 35:92-6. 2003
    ....

Research Grants83

  1. The effects of glucose on central vagal brainstem circuits
    KIRSTEEN NAIRN BROWNING; Fiscal Year: 2010
    ..b>Blood glucose levels oscillate throughout the day and increase dramatically following food intake;adaptive autonomic sensory ..
  2. Passivating Proteins in Implantable Glucose Sensors
    W Ward; Fiscal Year: 2004
    Inadequate control of blood glucose contributes to the complications of diabetes (renal, retinal, neural)...
  3. Glucose monitoring using polarized light
    Gerard L Cote; Fiscal Year: 2010
    Diabetes mellitus is a chronic disease that requires daily management to prevent large fluctuations in blood glucose levels and Diabetes disease management as well as biomedical sensor development is prime targets of the NIDDK and ..
  4. Glucose monitoring using polarized light
    GERARD COTE; Fiscal Year: 2007
    Diabetes mellitus is a chronic disease that requires daily management to prevent large fluctuations in blood glucose levels and Diabetes disease management as well as biomedical sensor development is prime targets of the NIDDK and NIBIB ..
  5. Effect of exendin-(9-39) on glucose metabolism in subjects with hyperinsulinism
    DIVA DE LEON; Fiscal Year: 2007
    ..Our overall hypothesis is that antagonism of the GLP-1 receptor by exendin-(9-39) will increase fasting blood glucose levels and decrease glucose requirement to maintain euglycemia in subjects with KATP HI as a result of ..
  6. Momentary Biobehavioral Effects on Physical Activity in Adults with T2 Diabetes
    CYNTHIA J FRITSCHI; Fiscal Year: 2010
    ..technology continuously over 6 days to measure physical activity (wrist actigraphy), fatigue (self-report), blood glucose levels (CGM), and related self-care behaviors (nightly diary), alongside retrospective measures of other ..
  7. MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related Gluconeogenesis
    Haiyan Xu; Fiscal Year: 2010
    ..In the insulin resistant diabetic state, blood glucose levels are elevated due to increased glucose production from the liver (mainly through de novo glucose ..
  8. MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related Gluconeogenesis
    Haiyan Xu; Fiscal Year: 2009
    ..In the insulin resistant diabetic state, blood glucose levels are elevated due to increased glucose production from the liver (mainly through de novo glucose ..
  9. MAP Kinase Phosphatase 3 (MKP-3) and Obesity-related Gluconeogenesis
    Haiyan Xu; Fiscal Year: 2010
    ..In the insulin resistant diabetic state, blood glucose levels are elevated due to increased glucose production from the liver (mainly through de novo glucose ..
  10. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William S Harris; Fiscal Year: 2010
    ..FA levels over several weeks and are less variable (analogous to hemoglobin A1C in the assessment of average blood glucose levels)...
  11. Red Blood Cell Fatty Acid Biomarkers and Cardiovascular Disease Risk
    William Harris; Fiscal Year: 2009
    ..FA levels over several weeks and are less variable (analogous to hemoglobin A1C in the assessment of average blood glucose levels)...
  12. Race and Long-Term Diabetes Self-Management in an HMO
    Dennis Ross Degnan; Fiscal Year: 2004
    ..will examine the complex relationships between race, diabetes self-management (including self-monitoring of blood glucose and diabetes drug therapy), glycemic control, and diabetes complications in a managed care setting over a nine-..
  13. ATP-SENSITIVE POTASSIUM CHANNELS AND INSULIN SECRETION
    Show Ling Shyng; Fiscal Year: 2010
    ATP-sensitive potassium (KATP) channels in pancreatic b-cells couple blood glucose concentrations to membrane excitability thus control insulin secretion...
  14. MODULAR BIO-BEHAVIORAL CLOSED-LOOP CONTROL OF TYPE 1 DIABETES
    Boris Kovatchev; Fiscal Year: 2009
    DESCRIPTION: By nature, the development of a closed-loop system (known as artificial pancreas) controlling blood glucose (BG) in diabetes is an interdisciplinary project involving physiology, behavioral science, and engineering...
  15. MODULAR BIO-BEHAVIORAL CLOSED-LOOP CONTROL OF TYPE 1 DIABETES
    Boris P Kovatchev; Fiscal Year: 2010
    DESCRIPTION: By nature, the development of a closed-loop system (known as artificial pancreas) controlling blood glucose (BG) in diabetes is an interdisciplinary project involving physiology, behavioral science, and engineering...
  16. Use of Continuous Glucose Sensors in Adolescents with Inadequate Diabetic Control
    Tim Wysocki; Fiscal Year: 2010
    ..quality and quantity of glucose data could be an excellent adjunct to conventional self-monitoring of blood glucose, permitting more informed diabetes decision-making...
  17. Use of Continuous Glucose Sensors in Adolescents with Inadequate Diabetic Control
    Tim Wysocki; Fiscal Year: 2011
    ..quality and quantity of glucose data could be an excellent adjunct to conventional self-monitoring of blood glucose, permitting more informed diabetes decision-making...
  18. Use of Continuous Glucose Sensors in Adolescents with Inadequate Diabetic Control
    Tim Wysocki; Fiscal Year: 2009
    ..quality and quantity of glucose data could be an excellent adjunct to conventional self-monitoring of blood glucose, permitting more informed diabetes decision-making...
  19. Novel Glucagon Modulators and the Closed Loop System
    Rubina Heptulla; Fiscal Year: 2009
    ..This method relies on the patient being engaged in blood glucose monitoring and insulin delivery, especially for meal boluses...
  20. Glycemic control in pediatric critical illness: The Ped-E-Trol trial
    MARK RANSFORD RIGBY; Fiscal Year: 2010
    ..We have determined that our protocol appears to be an efficient means to maintain our target blood glucose levels of 80-140 mg/dL without increasing rates of hypoglycemia...
  21. GLYCEMIC INDEX/GLYCEMIC LOAD AND BLOOD LIPIDS IN THE WHI
    James Shikany; Fiscal Year: 2004
    ..Recent evidence suggest that diets abundant in high-starch carbohydrates may have an adverse effect on blood glucose and insulin concentrations, resulting in alterations of blood lipids that may increase the risk of developing ..
  22. Mexican-American Trial of Community Health Workers-MATCH
    Steven Rothschild; Fiscal Year: 2007
    ..Trials show that self-management behaviors (self monitoring of blood glucose, taking medications as prescribed, and periodic scheduled clinic attendance) can make a positive difference in ..
  23. Novel Puerarin Analogs with Anti-Diabetic Activity
    NICHOLAS CAIRNS; Fiscal Year: 2007
    ..and/or promoting glucose disposal in the tissues may be beneficial for diabetic patients to control the blood glucose level in the postprandial state...
  24. Properties of Ion Channels that Control Secretion
    JOHN ENYEART; Fiscal Year: 2007
    ..Precise control of blood glucose by cortisol is essential because this sugar is the brain's primary energy source...
  25. Dopamine action in pancreatic islet function
    David W Piston; Fiscal Year: 2010
    ..b>Blood glucose homeostasis depends on glucose-stimulated insulin secretion (GSIS) from islet 2 cells, but we also know that ..