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| mouthwashesSummarySummary: Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed) Top Publications
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Publications
A method to compare four mouthrinses: time to gingivitis level as the primary outcome variableR Yates
Division of Restorative Dentistry, Dental School, Bristol, UK
J Clin Periodontol 29:519-23. 2002..Some modification of the method, primarily to group sizes, should improve specificity. The method has the considerable volunteer appeal of early exit, particularly when allocated to control or low activity treatments for plaque...
The effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc lactate on the microflora of oral halitosis patients: a dual-centre, double-blind placebo-controlled studyS Roldan
Universidad Complutense de Madrid, Spain
J Clin Periodontol 30:427-34. 2003..This study evaluated the microbial effects of a newly formulated mouthwash (Halita) on oral halitosis patients...
The rational use of oral care products in the elderlyR M Davies
Dental Health Unit, Manchester Science Park, Lloyd Street North, M15 6SH, Manchester, UK
Clin Oral Investig 8:2-5. 2004..Powered toothbrushes with an oscillation-rotation action are more effective in reducing plaque and improving gingival health than manual toothbrushes...
A 6-month clinical study assessing the safety and efficacy of two cetylpyridinium chloride mouthrinsesGeorge K Stookey
Indiana University Emerging Technologies Center, Indianapolis, Indiana 46202, USA
Am J Dent 18:24A-28A. 2005..To evaluate the effects of two experimental cetylpyridinium chloride (CPC) mouthrinses containing 0.075% and 0.10% CPC on the development of gingivitis and plaque versus a placebo control over a period of 6 months...
Effect of two new chlorhexidine mouthrinses on the development of dental plaque, gingivitis, and discolouration. A randomized, investigator-blind, placebo-controlled, 3-week experimental gingivitis studyK Lorenz
Department of Conservative Dentistry Medical Faculty, Dresden University of Technology, Dresden, Germany
J Clin Periodontol 33:561-7. 2006..The aim of this experimental gingivitis study was to assess the efficacy and safety of two new chlorhexidine (CHX) mouthrinses...
A high molecular mass cranberry constituent reduces mutans streptococci level in saliva and inhibits in vitro adhesion to hydroxyapatiteErvin I Weiss
Department of Prosthodontics, Faculty of Dentistry, Hebrew University Hadassah, Jerusalem, Israel
FEMS Microbiol Lett 232:89-92. 2004..The data suggest that the ability to reduce mutans streptococci counts in vivo is due to the anti-adhesion activity of the cranberry constituent...
Effect of different mouthrinses on morning breathD van Steenberghe
Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium
J Periodontol 72:1183-91. 2001..CHX-Alc and CHX-CPC-Zn mouthrinses result in a significant reduction of the microbial load of tongue and saliva...
The effect on early plaque formation, gingivitis and salivary bacterial counts of mouthwashes containing hexetidine/zinc, aminefluoride/tin or chlorhexidineA F Hefti
Department of Preventive Dentistry, University of Basel, Switzerland
J Clin Periodontol 14:515-8. 1987This study was designed to investigate the effectiveness of mouthwashes containing hexetidine/zinc (HZA) or tin (ASF) in inhibiting plaque formation and gingivitis in humans...
The antiplaque efficacy of pomegranate mouthrinseSmruti J Bhadbhade
Department of Periodontics and Oral Implantology, SDM College of Dental Sciences and Hospital, Dhawad, Karnataka, India
Quintessence Int 42:29-36. 2011..to evaluate the effect of a pomegranate-containing mouthrinse on plaque, determine whether it has any adverse effects, and evaluate its antibacterial properties against selected periodontopathogens in vitro...
Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositisE E Mazokopakis
Department of Internal Medicine, University General Hospital of Heraklion Crete, P.O. Box 1352, 71110 Heraklion, Crete, Greece
Phytomedicine 12:25-7. 2005..We report a case of MTX-induced oral mucositis in a patient with rheumatoid arthritis, who was successfully treated with Wild chamomile mouthwashes.
Inhibition of orally produced volatile sulfur compounds by zinc, chlorhexidine or cetylpyridinium chloride--effect of concentrationAlix Young
Department of Cariology, Faculty of Dentistry, University of Oslo, Oslo, Norway
Eur J Oral Sci 111:400-4. 2003..Although Zn had the best anti-VSC effect at 1 h, 0.2% CHX was at least as effective as 1% Zn at 3 h, most likely as a result of its unique substantivity...
The efficacy of amine fluoride/stannous fluoride in the suppression of morning breath odourMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Heverlee, Belgium
J Clin Periodontol 29:944-54. 2002..a control solution in the prevention of morning bad breath during an experimental period of 7 days without mechanical plaque control...
Comparative effects of different chlorhexidine mouth-rinse formulations on volatile sulphur compounds and salivary bacterial countsSilvia Roldán
Section of Graduate Periodontology, Faculty of Odontology, University Complutense, Madrid 28040, Spain
J Clin Periodontol 31:1128-34. 2004..And secondly, to validate the study model proposed in the evaluation of patients suffering from halitosis...
Prophylactic chlorhexidine oral rinse decreases ventilator-associated pneumonia in surgical ICU patientsT Genuit
VA Maryland Health Care System and University of Maryland School of Medicine, Baltimore, Maryland, USA
Surg Infect (Larchmt) 2:5-18. 2001..The purpose of this study was to determine whether adherence to a ventilator weaning protocol (WP) and the use of chlorhexidine gluconate (CH) oral rinse for oral hygiene would decrease the incidence of VAP in surgical ICU patients...
Microbiology and treatment of halitosisWalter J Loesche
Department of Microbiology and Immunology, School of Medicine, University of Michigan, Ann Arbor, USA
Periodontol 2000 28:256-79. 2002....
Oral care reduces incidence of ventilator-associated pneumonia in ICU populationsHideo Mori
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba 260 8677, Chuou, Japan
Intensive Care Med 32:230-6. 2006..To examine whether oral care contributes to preventing ventilator-associated pneumonia (VAP) in ICU patients...
Clinical and microbiological efficacy of chlorine dioxide in the management of chronic atrophic candidiasis: an open studyAbdel R Mohammad
The Ohio State University College of Dentistry, Section of Primary Care, Postle Hall Office 3058, 305 West 12th Avenue, Columbus, OH 43210, USA
Int Dent J 54:154-8. 2004..To assess the clinical and microbiological efficacy of chlorine dioxide (ClO2) as a topical antiseptic for the treatment of chronic atrophic candidiasis in geriatric patients...
A multifactorial investigation of the ability of oral health care products (OHCPs) to alleviate oral malodourC J Silwood
Room AW518, Medical Unit, 5th Floor, Alexandra Wing, Royal London Hospital, London E1 1BB, UK
J Clin Periodontol 28:634-41. 2001..CONCLUSIONS: We therefore conclude that oral health care products containing such oxohalogen oxidants may provide a useful therapeutic strategy for the treatment of oral malodour...
Effect of a carbohydrate mouthwash on running time-trial performanceMartin Whitham
Sport, Health and Exercise Sciences, University of Wales, Bangor, UK
J Sports Sci 25:1385-92. 2007..Blood lactate and glucose increased as a result of the exercise protocol, with no between-trial differences. In conclusion, there was no positive effect of a carbohydrate mouthwash on running performance of approximately 1 h duration...
Evidence for the microbicidal activity of a chlorine dioxide-containing oral rinse formulation in vivoM Grootveld
St Bartholomew s and the Royal London School of Medicine and Dentistry, London, United Kingdom
J Clin Dent 12:67-70. 2001..The therapeutic, microbial and biochemical ramifications of the results obtained are discussed...
Analysis of the effect of DNA purification on detection of human papillomavirus in oral rinse samples by PCRElizabeth Sugar
Department of Epidemiology, Johns Hopkins University, Baltimore, MD 21231, USA
J Clin Microbiol 43:5526-35. 2005..The method of DNA purification significantly affects the detection of HPV genomic DNA from oral rinse samples and may result in exposure misclassification that could contribute to the inconsistent associations reported in the literature...
Rinsing with chlorhexidine gluconate solution after brushing and flossing teeth: a systematic review of effectivenessJafar Kolahi
Torabinejad Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Quintessence Int 37:605-12. 2006..CONCLUSION: To optimize the antiplaque effect of CHX, it seems best that the interval between toothbrushing and rinsing with CHX be more than 30 minutes, cautiously close to 2 hours after brushing...
Use of buccal cells collected in mouthwash as a source of DNA for clinical testingE M Heath
Department of Chemistry Research and Development, Gentra Systems Inc, Minneapolis, Minn 55441, USA
Arch Pathol Lab Med 125:127-33. 2001..Buccal cells, if collected and purified efficiently, offer an acceptable source for DNA to be used in research and clinical applications...
The effect of carbohydrate mouth rinse on 1-h cycle time trial performanceJames M Carter
Human Performance Laboratory, School of Sport and Exercise Sciences, The University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK
Med Sci Sports Exerc 36:2107-11. 2004..The nature and role of putative CHO receptors in the mouth warrants further investigation...
Effectiveness of 0.12% chlorhexidine gluconate oral rinse in reducing prevalence of nosocomial pneumonia in patients undergoing heart surgerySusan Houston
St. Luke's Episcopal Hospital, Houston, Tex, USA
Am J Crit Care 11:567-70. 2002....
Carbohydrate mouth rinsing in the fed state: lack of enhancement of time-trial performanceMilou Beelen
Nutrition and Toxicology Research Institute, Maastricht, Maastricht University, The Netherlands
Int J Sport Nutr Exerc Metab 19:400-9. 2009..Carbohydrate mouth rinsing does not improve time-trial performance when exercise is performed in a practical, postprandial setting...
Comparative antiplaque and antigingivitis effectiveness of a chlorhexidine and an essential oil mouthrinse: 6-month clinical trialC H Charles
Dental Products Testing, West Palm Beach, FL, USA
J Clin Periodontol 31:878-84. 2004..The objective of this study was to compare the antiplaque and antigingivitis effectiveness and the side-effect profiles of an essential oil-containing mouthrinse and a chlorhexidine-containing mouthrinse...
Impact of mouthrinses on morning bad breath in healthy subjectsM D Carvalho
Department of Prosthodontics and Periodontics, Faculty of Dentistry of Piracicaba, University of Campinas, Piracicaba, SP, Brazil
J Clin Periodontol 31:85-90. 2004..CONCLUSIONS: These findings suggest that mouthrinses can reduce morning bad breath, and that such a reduction is not attributable only to the reduction of supragingival plaque formation...
Relationship of oral malodor to periodontitis: evidence of independence in discrete subpopulationsA Bosy
Department of Periodontics, University of Toronto, Faculty of Dentistry, ON
J Periodontol 65:37-46. 1994..These data indicate that a large proportion of individuals with oral malodor are periodontally healthy and that the mucosal surface of the tongue is a major site of oral malodor production...
Clinical effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc-lactate on oral halitosis. A dual-center, double-blind placebo-controlled studyE G Winkel
Clinic for Periodontology Amsterdam, de Boelelaan 589, 1082 RM Amsterdam, The Netherlands
J Clin Periodontol 30:300-6. 2003..The aim of this double-blind, parallel study was to test the clinical efficacy of a newly developed mouthrinse in the treatment of oral halitosis in patients without periodontitis...
Prevention of nosocomial infection in cardiac surgery by decontamination of the nasopharynx and oropharynx with chlorhexidine gluconate: a randomized controlled trialPatrique Segers
Department of Cardiothoracic Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
JAMA 296:2460-6. 2006..Nosocomial infections are an important cause of morbidity and mortality after cardiac surgery. Decolonization of endogenous potential pathogenic microorganisms is important in the prevention of nosocomial infections...
Mouth rinse but not ingestion of a carbohydrate solution improves 1-h cycle time trial performanceA Pottier
Department of Movement and Sports Sciences, Ghent University, Ghent, Belgium
Scand J Med Sci Sports 20:105-11. 2010..Blood glucose concentration increased after ingestion of but not after mouth rinse with CES. The interesting finding of the present study is that rinsing the mouth with but not ingestion of CES resulted in improved performance...
Short-term side effects of 0.2% alcohol-free chlorhexidine mouthrinse used as an adjunct to non-surgical periodontal treatment: a double-blind clinical studyCem A Gurgan
Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey
J Periodontol 77:370-84. 2006..2% chlorhexidine (CHX) mouthrinse without alcohol used as an adjunct to non-surgical periodontal treatment and to elucidate the relationship between the subjective and objective evaluations...
Influence of alcohol in mouthwashes containing triclosan and zinc: an experimental gingivitis studyJ M Almerich
Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain
J Clin Periodontol 32:539-44. 2005An experimental gingivitis model was used to analyse the influence of alcohol in mouthwashes containing 0...
Odor reduction potential of a chlorine dioxide mouthrinseJ Frascella
TKL Research, Inc, Paramus, New Jersey, USA
J Clin Dent 9:39-42. 1998..Thus, this study demonstrates that a one-time use of a chlorine dioxide-containing mouthrinse significantly improves mouth odor pleasantness and reduces mouth odor intensity for at least 4 hours...
The effectiveness of commonly used mouthwashes for the prevention of chemotherapy-induced oral mucositis: a systematic reviewC M J Potting
Department of Haematology, Radboud University Nijmegen Medical Centre, The Netherlands
Eur J Cancer Care (Engl) 15:431-9. 2006..9%, water salt soda solution and chamomile mouthwash are also recommended. However, the effectiveness of these mouthwashes is unclear...
Toxicity screening of mouthwashes in the pollen tube growth test: safety assessment of recommended dilutions of twenty brandsUdo Kristen
Institute of General Botany, University of Hamburg, Ohnhorstrasse 18, D-22609 Hamburg, Germany
In Vivo 18:803-7. 2004..The IC50s clearly revealed that none of the tested mouthwashes should cause acute irritation if used at the recommended dilution...
Hemostatic mouthwashes in anticoagulated patients undergoing dental extractionEdna Patatanian
Department of Pharmacy Practice, College of Pharmacy, Southwestern Oklahoma State University, Oklahoma City, OK 73103 2600, USA
Ann Pharmacother 40:2205-10. 2006..To evaluate the efficacy and safety of local acting hemostatic agents in patients who are undergoing dental extraction(s) and are taking oral anticoagulants...
The role of alcohol in oral carcinogenesis with particular reference to alcohol-containing mouthwashesM J McCullough
Melbourne Dental School, The University of Melbourne, Victoria
Aust Dent J 53:302-5. 2008..Further, we review the literature that associates alcohol-containing mouthwashes and oral cancer...
Prevention of upper respiratory tract infections by gargling: a randomized trialKazunari Satomura
Department of Public Health and International Health, Kyoto University School of Public Health, Kyoto, Japan
Am J Prev Med 29:302-7. 2005..055). CONCLUSIONS: Simple water gargling was effective to prevent URTIs among healthy people. This virtually cost-free modality would appreciably benefit the general population...
The effect of three mouthwashes on radiation-induced oral mucositis in patients with head and neck malignancies: a randomized control trialP D Kumar Madan
Department of Preventive and Community Dentistry, Ragas Dental College and Hospital, Chennai 600 119, India
J Cancer Res Ther 4:3-8. 2008The present study was done to assess the effect of three alcohol-free mouthwashes on radiation-induced oral mucositis in patients with head and neck malignancies.
Radiation-induced mucositis: a randomized clinical trial of micronized sucralfate versus salt & soda mouthwashesMarylin J Dodd
Department of Physiological Nursing, UCSF School of Nursing, Box 0610, San Francisco, CA 94143 0610, USA
Cancer Invest 21:21-33. 2003..Patients who developed RT-induced mucositis anytime during their course of RT were randomized to one of the two mouthwashes and followed to the completion of RT and at one month following RT. Two referral sites were used for the study...
Influence of oral detergents and chlorhexidine on soft-layer electrokinetic parameters of the acquired enamel pellicleH J Busscher
Department of Biomedical Engineering, University of Groningen, Groningen, The Netherlands
Caries Res 37:431-6. 2003....
Comparison of two clinical methods for evaluating the anti-plaque efficacy of a dentifriceTao Xu
Colgate Palmolive Technology Center Piscataway, NJ, USA
J Clin Dent 16:97-102. 2005....
The development of a new dental probe and a new plaque indexTao Xu
Colgate Palmolive Technology Center, Piscataway, NJ, USA
J Clin Dent 14:93-7. 2003..The purpose of this research was to evaluate the efficacy of three marketed antiplaque products using the MGMPI...
The comparative effects of 0.12% chlorhexidine and herbal oral rinse on dental plaque-induced gingivitisElizabeth N Southern
J Dent Hyg 80:12. 2006..005 and p=.032, respectively). The effects of HBR on reducing mean GI, BOP, and PI scores were not statistically greater than placebo at any time during the study...
Differences in efficacy of two commercial 0.2% chlorhexidine mouthrinse solutions: a 4-day plaque re-growth studyNicole B Arweiler
Department of Operative Dentistry and Periodontology, Dental School and Hospital, Albert Ludwigs University, Freiburg, Germany
J Clin Periodontol 33:334-9. 2006..The purpose of this clinical cross-over study was to examine the antibacterial and plaque-inhibiting properties of two chlorhexidine solutions compared with a negative control...
Influence of a SLS-containing dentifrice on the anti-plaque efficacy of a chlorhexidine mouthrinseD A C Van Strydonck
Department of Periodontology, Academic Centre for Dentistry, Amsterdam, The Netherlands
J Clin Periodontol 31:219-22. 2004..The purpose of the present study was to investigate the effect of toothbrushing with a SLS-containing dentifrice in one jaw, on the plaque inhibition of a CHX mouthrinse in the opposite jaw during a 4-day study period...
Practical protocols for the prevention of dental disease in community settings for people with special needs: the protocolsPaul Glassman
University of the Pacific School of Dentistry, USA
Spec Care Dentist 23:160-4. 2003..This article presents a set of practical protocols for preventing dental disease in people with special needs. These protocols are designed to be used in community settings outside of a dental office...
A combined therapeutic approach to manage oral halitosis: a 3-month prospective case seriesSilvia Roldán
Section of Graduate Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain
J Periodontol 76:1025-33. 2005..The aim of this study was to evaluate the effects of a combined mechanical and pharmacological approach to treat oral halitosis on clinical and microbiological outcomes on patients followed for 3 months...
Chlorhexidine with an Anti Discoloration System. A comparative studyF Bernardi
Department of Dental Sciences, Degree course for Dental Hygienists, Alma Mater Studiorum, University of Bologna, Italy
Int J Dent Hyg 2:122-6. 2004..contains chlorhexidine and Anti Discoloration System (ADS), not only to prevent plaque formation like the other mouthwashes containing chlorhexidine but also to avoid staining that is one of the most frequent side-effects...
A randomized clinical trial on the short-term clinical and microbiological effects of the adjunctive use of a 0.05% chlorhexidine mouth rinse for patients in supportive periodontal careSagrario Santos
Section of Graduate Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain
J Clin Periodontol 31:45-51. 2004..CONCLUSIONS: The newly formulated mouth rinse demonstrated short-term plaque-inhibitory activity. This was associated with a reduction in the total load of anaerobic subgingival microflora...
The prevention of plaque re-growth by toothpastes and solutions containing block copolymers with and without polypeptideN C Claydon
Department of Oral and Dental Science, University of Bristol, Bristol, UK
J Clin Periodontol 32:545-8. 2005..This study investigated whether two anti-adherent systems could inhibit plaque re-growth in the mouth when rinsed as a solution or as a toothpaste slurry...
The effect of a polyhexamethylene biguanide mouthrinse compared with a triclosan rinse and a chlorhexidine rinse on bacterial counts and 4-day plaque re-growthA Welk
Department of Operative Dentistry, Periodontology, and Paediatric Dentistry, University of Greifswald, Germany
J Clin Periodontol 32:499-505. 2005..12% aqueous chlorhexidine solution (B), a commercially available 0.3% triclosan/2.0% polyvinyl methyl ether maleic acid copolymer mouthrinse (Colgate Total Plax) (C), and a negative control placebo rinse (10% ethanol, flavour) (D)...
A 0.05% cetyl pyridinium chloride/0.05% chlorhexidine mouth rinse during maintenance phase after initial periodontal therapyMarc Quirynen
Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 32:390-400. 2005..CONCLUSIONS: The results of this study demonstrated the potential of a new CHX 0.05%+CPC 0.05% non-alcoholic formulation as an effective antiplaque agent for long-term use with reduced subjective side effects...
Short-term anti-plaque effect of two chlorhexidine varnishesJan Cosyn
Department of Periodontology, School of Dental Medicine, Free University of Brussels VUB, Brussels, Belgium
J Clin Periodontol 32:899-904. 2005..Reports regarding their anti-plaque effect on a clinical level are limited to non-existing as opposed to their microbiological impact on plaque formation...
Plaque inhibition of two commercially available chlorhexidine mouthrinsesD A C Van Strydonck
Department of Periodontology, Academic Centre for Dentistry, Amsterdam, The Netherlands
J Clin Periodontol 32:305-9. 2005..12% CHX non-alcohol base with 0.05% cetyl pyridinium chloride (Cpc) versus 0.2% CHX alcohol base)...
The effect of systemic administration of ibuprofen in the experimental gingivitis modelSatoshi Sekino
Department of Periodontology, Faculty of Odontology, , , Sweden
J Clin Periodontol 32:182-7. 2005..CONCLUSION: It is suggested that ibuprofen administered via the systemic route has an effect on gingivitis but not on de novo plaque formation...
Essentials oils for implant maintenance: an evidence based appraisalV Yengopal
School of Public Health, Division of Public Oral Health, Wits
SADJ 59:296, 298. 2004
Effects of post-surgical cleansing protocols on early plaque control in periodontal and/or periimplant wound healingF Heitz
School of Dental Medicine, University of Berne, Berne, Switzerland
J Clin Periodontol 31:1012-8. 2004..CONCLUSION: The use of specific post-surgical cleansing protocols including the introduction of mechanical cleansing at day 3, using local application of CHX in addition to daily rinsing with CHX may be recommended...
The effect of two different dental gels and a mouthwash on plaque and gingival scores: a six-week clinical studyM R Pai
Zydus Research Centre, NDDS Department, Sarkhej bavla NH 8A, Changodhar Ahmedabad 382213 Gujarat, India
Int Dent J 54:219-23. 2004..To evaluate the clinical efficacy of two gel formulations containing chlorhexidine gluconate and neem extract with a commercially available chlorhexidine gluconate mouthwash...
Effects of low dose chlorhexidine mouthrinses on oral bacteria and salivary microflora including those producing hydrogen sulfideP K Sreenivasan
Colgate Palmolive Company, Piscataway, NJ, USA
Oral Microbiol Immunol 19:309-13. 2004..This investigation examined the efficacy of lower concentrations of chlorhexidine...
A simple approach to examine early oral microbial biofilm formation and the effects of treatmentsP K Sreenivasan
Colgate Palmolive Company, River Road, Piscataway, NJ, USA
Oral Microbiol Immunol 19:297-302. 2004..A simple in vivo approach to examine early dental plaque formation in the human mouth and to determine the effects of common dietary and oral hygiene procedures on biofilm formation is reported...
The effect of a chlorhexidine regimen on de novo plaque formationSatoshi Sekino
, Faculty of Odontology, Department of Periodontology, , Sweden
J Clin Periodontol 31:609-14. 2004..CONCLUSION: Habitat is critical in controlling the bacterial composition of the dental biofilm. The microbiota will tend to go back to the one that is characteristic of a given subject, once chemical antimicrobial means are withdrawn...
Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month studyN Sharma
BioSci Research Canada, Mississauga, Ontario
J Am Dent Assoc 135:496-504. 2004..CLINICAL IMPLICATIONS: An EO-containing mouthrinse is an effective adjunct to regular brushing and flossing. Therefore, the BFEO regimen can be beneficial for patients with gingival inflammation...
A method to study sustained antimicrobial activity of rinse and dentifrice components on biofilm viability in vivoH C van der Mei
Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Clin Periodontol 33:14-20. 2006..To develop an improved method for quantitative assessment of antimicrobial efficacy and substantivity of mouth rinses and dentifrices on in vivo treated plaque...
Randomized controlled clinical trials on agents used for chemical plaque controlS Paraskevas
Academic Center for Dentistry Amsterdam ACTA, Amsterdam, The Netherlands
Int J Dent Hyg 3:162-78. 2005..The present review deals with randomized controlled clinical trials of >or=6 months in duration, on the use of those agents and their effects on plaque and gingival inflammation...
An in vitro oral biofilm model for comparing the efficacy of antimicrobial mouthrinsesS Shapiro
Institute for Oral Microbiology and General Immunology, Center for Dentistry, Oral Medicine, and Maxillofacial Surgery, University of Zurich, Switzerland
Caries Res 36:93-100. 2002..This polyspecies biofilm model can be a valuable tool for preclinical testing of antiplaque formulations, particularly during the product development stage...
Effect of an amine-fluoride-triclosan mouthrinse on plaque regrowth and biofilm vitalityNicole B Arweiler
Albert Ludwigs University of Freiburg, Dept of Operative Dentistry and Periodontology, Freiburg, Germany
J Clin Periodontol 29:358-63. 2002....
Acidogenicity of buccal plaque after a single rinse with amine fluoride - stannous fluoride mouthrinse solutionJ J M Damen
Department of Cariology Endodontology Pedodontology, Academic Centre for Dentistry Amsterdam (ACTA, The Netherlands
Caries Res 36:53-7. 2002..To conclude, AmF-SnF2 in both Meridol formulations and CHX were shown to have a similar potency to inhibit acid production after a single rinse...
Prevention of maternal bacterial transmission on children's dental-caries-development: 4-year results of a pilot study in a rural-child populationErtugrul Ercan
University of Kirikkale, Dental Faculty, Department of Operative Dentistry, Turkey
Arch Oral Biol 52:748-52. 2007....
The effect of polyvinyl pyrrolidone on the clinical activity of 0.09% and 0.2% chlorhexidine mouthrinsesN Claydon
Division of Restorative Dentistry, Dental School, Bristol, UK
J Clin Periodontol 28:1037-44. 2001..These data are further evidence that chlorhexidine oral hygiene products, which, do not or claim not to cause staining, are most probably lacking efficacy...
The clinical efficacy of triclosan/copolymer and other common therapeutic approaches to periodontal healthR M Davies
Dental Health Unit, University of Manchester, Manchester, UK
Clin Microbiol Infect 13:25-9. 2007..The delivery of such benefits has positive implications for the oral health of individuals and populations...
A comparative study of two mouthrinses on plaque and gingivitis in school children in the age group of 13-16 years in Bangalore cityK Jayaprakash
Department of Preventive and Community Dentistry, Rama Dental College and Hospital, Kanpur 208 024, India
J Indian Soc Pedod Prev Dent 25:126-9. 2007..This combination along with the well-established effect of fluoride in the prevention of caries, presents an important contribution to dental public health...
Treatment protocol to control Streptococcus mutans level in an orthodontic patient with high caries riskPatricia V M Alves
Department of Orthodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Am J Orthod Dentofacial Orthop 133:91-4. 2008..At the end of orthodontic treatment, periodontal health was observed, and enamel surfaces showed signs of remineralization...
Oral hygiene regimens, plaque control, and gingival health: a two-month clinical trial with antimicrobial agentsAaron R Biesbrock
The Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
J Clin Dent 18:101-5. 2007..The purpose of this study was to examine the effects of various product combinations involving brush, paste, rinse, and floss on the prevention of plaque regrowth and gingivitis...
Effect of various mouthwashes on the levels of interleukin-2 and interferon-gamma in chronic gingivitisShivalal Sharma
Department of Periodontics, College of Dental Surgery, B P Koirala Institute of Health Sciences, Dharan, Nepal
J Clin Pediatr Dent 32:111-4. 2008The aim of this double blind study was to evaluate the effect of various mouthwashes: Chlorhexidine, Essential oil, Azadirachta indica (Neem) extract, and Povidone iodine on gingival tissue interleukin-2 (IL-2) and interferon-gamma (IFN-..
The effects of an essential oil and an amine fluoride/stannous fluoride mouthrinse on supragingival plaque regrowthGiuseppe Pizzo
Department of Oral Sciences, Section of Periodontology, University of Palermo, Palermo, Italy
J Periodontol 79:1177-83. 2008..The aim of the study was to investigate the plaque-inhibiting effects of two commercially available mouthrinses containing ASF and EO, respectively...
Comparison of the use of different modes of mechanical oral hygiene in prevention of plaque and gingivitisNanning A M Rosema
Department of Periodontology, Academic Center for Dentistry Amsterdam, Amsterdam, The Netherlands
J Periodontol 79:1386-94. 2008..The objective of this study was to evaluate the effect of an oscillating/rotating/pulsating powered toothbrush on plaque and gingivitis prevention over a 9-month period...
Chlorine dioxide and chlorhexidine mouthrinses compared in a 3-day plaque accumulation modelSpiros Paraskevas
Department of Periodontology, Academic Center for Dentistry Amsterdam, Amsterdam, The Netherlands
J Periodontol 79:1395-400. 2008..The aim of this study was to investigate the inhibiting effect of a chlorine dioxide mouthrinse as opposed to a mouthrinse containing chlorhexidine (0.20%) during 3 days of plaque accumulation...
The effect of 0.12% chlorhexidine dentifrice gel on plaque accumulation: a 3-day non-brushing modelD E Slot
School for Dental Hygiene, INHOLLAND University of Professional Education, Amsterdam, The Netherlands
Int J Dent Hyg 5:45-52. 2007..Effective chemotherapeutic agents as an adjunct to mechanical plaque control would therefore be valuable. Chlorhexidine (CHX) mouthwash has proved to be an effective inhibitor of plaque accumulation...
Plaques from different individuals yield different microbiota responses to oral-antiseptic treatmentSara K Filoche
Dental Research Group, Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
FEMS Immunol Med Microbiol 54:27-36. 2008..These findings indicate that efficacious caries treatments would depend on the responses of an individual's microbiota, which may differ from person to person...
Clinical efficacy of flossing versus use of antimicrobial rinsesStefan Zimmer
Department of Operative and Preventive Dentistry and Endodontics, Heinrich Heine University of Duesseldorf, Dusseldorf, Germany
J Periodontol 77:1380-5. 2006..This alternative could be a mouthrinse with antimicrobial activity for daily use. The aim of the present study was to evaluate the efficacy of two mouthrinses in reducing interdental plaque and gingivitis compared to dental floss...
A salivary incubation test for evaluation of oral malodor: a pilot studyMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Periodontol 74:937-44. 2003....
Chlorhexidine mouthrinse in combination with an SLS-containing dentifrice and a dentifrice slurryD A C Van Strydonck
Department of Periodontology, Academic Centre for Dentistry Amsterdam, ACTA, Louwesweg, EA Amsterdam, The Netherlands
J Clin Periodontol 33:340-4. 2006..5% sodium lauryl sulphate (SLS)-containing dentifrice to the effect of the same rinse when used alone, or when preceded by rinsing with an SLS-containing slurry...
Benefit of "one-stage full-mouth disinfection" is explained by disinfection and root planing within 24 hours: a randomized controlled trialMarc Quirynen
Department of Periodontology, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 33:639-47. 2006..This parallel, single blind RCT study aimed to compare several full-mouth treatment strategies with each other...
Evidence-based control of plaque and gingivitisA Santos
Department of Periodontology, Universitat Internacional de Catalunya, Bercelona, Spain
J Clin Periodontol 30:13-6. 2003..To date, two antiseptic mouthwashes have received the ADA Seal of Acceptance: Peridex (Zila Pharmaceuticals, Phoenix, AZ, USA; CHX, chlorhexidine) ..
The effect of toothbrushing regimens on the plaque inhibitory properties of an experimental cetylpyridinium chloride mouthrinseJon Witt
Health Care Research Center, Procter and Gamble Company, Mason, OH 45040 8006, USA
J Clin Periodontol 33:737-42. 2006..07% cetylpyridinium chloride (CPC) mouthrinse...
[Delmopinol--an alternative to chlorhexidine?]Nicole B Arweiler
Poliklinik für Zahnerhaltungskunde und Parodontologie, Albert Ludwigs Universitat, Freiburg, Deutschland
Schweiz Monatsschr Zahnmed 113:136-42. 2003..For the time being there is a lack of studies comparing the efficacy of delmopinol to that of other antibacterial substances such as amine fluoride/stannous fluoride, triclosan/copolymer or cetylpyridinium chloride...
In vivo antiplaque efficacy of combined antimicrobial dentifrice and rinse hygiene regimensDonald J White
Procter and Gamble Company, Mason Business Center, OH 45040, USA
Am J Dent 21:189-96. 2008..To evaluate using digital plaque image analysis the antiplaque efficacy of oral care regimens including use of antimicrobial toothpaste in combination with antimicrobial mouthrinse...
A meta-analysis of six-month studies of antiplaque and antigingivitis agentsJohn C Gunsolley
Department of Periodontics, Virginia Commonwealth University, Richmond, VA 23298, USA
J Am Dent Assoc 137:1649-57. 2006..In addition, the author solicited unpublished studies from manufacturers...
Antiplaque biocides and bacterial resistance: a reviewPrem Sreenivasan
Colgate-Palmolive Company, Piscataway, New Jersey 08855, USA
J Clin Periodontol 29:965-74. 2002....
Plaque-inhibiting effect of bioadhesive mucosal tablets containing chlorhexidine in a 4-day plaque regrowth modelP Coessens
Department of Periodontology, Dental School, Faculty of Medicine and Health Sciences, Gent University, Gent, Belgium
Clin Oral Investig 6:217-22. 2002..2% CHX rinses. However, unpleasant taste and superficial mucosal lesions are local side effects to be considered...
Efficacy of an amine fluoride-triclosan mouthrinse as compared to the individual active ingredientsNicole B Arweiler
Department of Operative Dentistry and Periodontology, Albert Ludwigs University, Freiburg, Germany
J Clin Periodontol 30:192-6. 2003..A placebo solution (PLA) and a 0.2% chlorhexidine solution (CHX) served as negative and positive controls, respectively...
Oral health, mouthwashes and cancer--what is the story?David Conway
Dental Public Health Unit, Dental School, Medical Faculty, University of Glasgow, Glasgow, Scotland, UK
Evid Based Dent 10:6-7. 2009..Both studies were coordinated by the International Agency for Research on Cancer according to an identical protocol for both case and control recruitment...
Topical corticosteroids in association with miconazole and chlorhexidine in the long-term management of atrophic-erosive oral lichen planus: a placebo-controlled and comparative study between clobetasol and fluocinonideM Carbone
Department of Oral Medicine, School of Medicine and Dentistry, University of Turin, Italy
Oral Dis 5:44-9. 1999..To evaluate the efficacy of a combination of topical corticosteroids with topical antimycotic drugs in the therapy of atrophic-erosive forms of oral lichen planus (OLP)...
Safety evaluation of topical applications of ethanol on the skin and inside the oral cavityDirk W Lachenmeier
Chemisches und Veterinaruntersuchungsamt CVUA Karlsruhe, Weissenburger Strasse 3, D 76187 Karlsruhe, Germany
J Occup Med Toxicol 3:26. 2008..g. medicinal products like hand disinfectants in occupational settings, cosmetics like hairsprays or mouthwashes, pharmaceutical preparations, and many household products)...
The effectiveness of triclosan-incorporated plastic against bacteria on beef surfacesC N Cutter
U S Department of Agriculture, Agricultural Research Service, Roman L Hruska U S Meat Animal Research Center, Clay Center, Nebraska 68933, USA
J Food Prot 62:474-9. 1999..been incorporated into a variety of personal hygiene products, including hand soaps, deodorants, shower gels, mouthwashes, and toothpastes...
Comparison of granulocyte-macrophage colony-stimulating factor and sucralfate mouthwashes in the prevention of radiation-induced mucositis: a double-blind prospective randomized phase III studyKauko Saarilahti
Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
Int J Radiat Oncol Biol Phys 54:479-85. 2002To compare granulocyte-macrophage colony-stimulating factor (GM-CSF) mouthwashes with sucralfate mouthwashes in the prevention of radiation-induced mucositis.
[The topical treatment of atrophic-erosive oral lichen planus with fluocinonide in a bioadhesive gel, chlorhexidine and miconazole gel. A totally open trial]M Carbone
Istituto Policattedra di Clinica, Universita degli Studi, Torino
Minerva Stomatol 45:61-8. 1996..Moreover, chlorhexidine (Plakout) 0.12%, 3 mouthwashes/daily and miconazole gel (Micotef) applied 1 times/daily were used for the entire period of the steroid therapy ..
Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosanW H Ward
AstraZeneca, Mereside, Macclesfield, Cheshire, U K
Biochemistry 38:12514-25. 1999Triclosan is used widely as an antibacterial agent in dermatological products, mouthwashes, and toothpastes. Recent studies imply that antibacterial activity results from binding to enoyl (acyl carrier protein) reductase (EACPR, EC 1.3.1...
Research Grants
- CONTROL OF PERIODONTAL INFECTIONSSigmund Socransky; Fiscal Year: 2003..These include effective antibacterial dentifrices and mouthwashes, powered toothbrushes, local drug delivery systems and better systemic antimicrobial therapies...
- Mulago Inpatient Noninvasive Diagnosis of Pneumocystis Pneumonia (MIND PCP) StudyJohn Davis; Fiscal Year: 2007..Diagnosing pneumonia by standard methods is impossible because of limited resources. This study will test if DNA- fingerprinting of special mouthwashes can accurately diagnose HIV-related pneumonia, and save lives.
- Taste Quality Coding Of SaltsSTEVEN ST JOHN; Fiscal Year: 2004..mechanism is inhibited by cetylpiridinium chloride (CPC), an over-the-counter surface disinfectant used in mouthwashes, fluoride rinses, and snore-relief sprays...
- Symptom Interpretation & Oral Health among Harlem AdultsKarolynn Siegel; Fiscal Year: 2005..e. oral health behaviors). Particularly brushing, flossing, use of interdental devices, use of mouthwashes, and regular dental visits...
- Guided Pocket Recolonization (GPR) in PeriodontitisMarc Quirynen; Fiscal Year: 2004..Clinical data will be collected after 2, 4, 6, 8 and 12 weeks. The results should indicate the possible role for commensal organisms in periodontal disease and subgingival biofilm formation. ..
- Localized Aggressive Periodontitis: Microbial & Host Markers for SusceptibilityDaniel Fine; Fiscal Year: 2009....
- Oral Immunology/Microbiology Annual MeetingDaniel Fine; Fiscal Year: 2003..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
- Microbial Markers for Periodontal Disease in ChildrenDaniel Fine; Fiscal Year: 2005....
- Attachment of Oral Actinobacillus to EpitheliumDaniel Fine; Fiscal Year: 2007..The longterm goal of this application is to use this information to identify targets for therapeutic agents that can interfere with attachment of Aa to oral tissues and thus prevent colonization leading to LAP. ..
- Localized Aggressive Periodontitis: Microbial & Host Markers for SusceptibilityDaniel Fine; Fiscal Year: 2009....
- Oral Immunology/Microbiology Research Group Annual MtgDaniel Fine; Fiscal Year: 2003..Perpetuation of the OIMRG and its annual meetings greatly enhances the spirit of collegial interaction/collaboration among investigators with expertise in immunology and microbial pathogenesis as related to oral health and disease. ..
- Localized Aggressive Periodontitis: Microbial & Host Markers for SusceptibilityDaniel H Fine; Fiscal Year: 2010....
- Impact of Oral bacterial interactions on periodontitisEric Reynolds; Fiscal Year: 2004..gingivalis, T. denticola, B. forsythus and F. nucleatum grown in monoculture and as polymicrobial cultures using 2D-gel electrophoresis, mass spectrometry and Western blotting. ..
- Development of a P.gingivalis vaccineEric Reynolds; Fiscal Year: 2006..The recombinant proteins, protein fragments and synthetic peptide multivalent constructs will be tested as defined vaccines against P. gingivalis in murine models of disease. ..
- Identification of Uncultivated and Unrecognized Pathogens of PeriodontitisANNE DENISE HAFFAJEE; Fiscal Year: 2010..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
- Identification of Uncultivated and Unrecognized Pathogens of PeriodontitisAnne Haffajee; Fiscal Year: 2009..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
- Three Periodontal Therapies in Current & Non-SmokersAnne Haffajee; Fiscal Year: 2007..The proposed investigation should provide a model to examine methods that could be useful in treating compromised patients whether compromised by harmful habits such as smoking, systemic disease, or genetic background. ..
- Longitudinal Study of Fluoride, Diet, Caries & FluorosisSteven Levy; Fiscal Year: 2007..As studies involving recruitment and successful retention of a cohort from birth are extremely rare, the Iowa Fluoride Study offers a unique opportunity to study these relationships in unprecedented detail. ..
- Identification of Uncultivated and Unrecognized Pathogens of PeriodontitisAnne Haffajee; Fiscal Year: 2007..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
- Fluoride & Other Factors in Childhood and Adolescent Bone DevelopmentSteven M Levy; Fiscal Year: 2010..Findings will improve our understanding of the best strategies to optimize skeletal health and prevent future bone disease. ..
- LONGITUDINAL STUDY--FLUORIDE EXPOSURE & DENTAL FLUORIDESteven Levy; Fiscal Year: 1993....
- MICROBIAL ASSOCIATIONS IN PERIODONTAL HEALTH AND DISEASEAnne Haffajee; Fiscal Year: 2000..In addition the importance and biological basis of supragingival plaque control in the treatment and prevention of periodontal diseases and in maintaining stability of the periodontium will be determined. ..
- FLUORIDE AND OTHER FACTORS IN CHILDHOOD BONE DEVELOPMENTSteven Levy; Fiscal Year: 2002....
- LONGITUDINAL STUDY OF FLUORIDE EXPOSURES & FLUORIDESteven Levy; Fiscal Year: 2004....
- LONGITUDINAL STUDY--FLUORIDE EXPOSURES & FLUOROSISSteven Levy; Fiscal Year: 1999..The ultimate goal will be to provide the scientific basis necessary to assure that fluorides can be used appropriately for maximum public health caries prevention with minimal dental fluorosis risk. ..
- EFFECT OF ANTIBIOTICS ON ORAL BIOFILMS IN VIVOAnne Haffajee; Fiscal Year: 2001..abstract_text> ..
- MICROBIAL ASSOCIATIONS IN PERIODONTAL HEALTH AND DISEASEAnne Haffajee; Fiscal Year: 2006..These data will provide a basis for understanding microbial community structure, ecological relationships and define desired microbiological end-point of therapy. ..
- Human Tissue Model For Heterosexual HIV TransmissionMitchell Klausner; Fiscal Year: 2003..Protocols for irritation studies will be finalized and the mechanisms of HIV infection and transmission in the tissue will be delineated. Finally, methodology for testing HIV microbicides will be developed. ..
- AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIESFrank Scannapieco; Fiscal Year: 2001..Such studies are crucial to better understand oral biofilm formation, which causes dental caries and periodontitis. ..
- Intervention Planning to Reduce Nursing Home PneumoniaVincent Quagliarello; Fiscal Year: 2005..A feasible and effective intervention for pneumonia prevention will hold great promise in reducing clinical morbidity and costs among this vulnerable population of citizens. ..
- In Vitro Skin Model for Percutaneous Absorption StudiesMitchell Klausner; Fiscal Year: 2002..In addition, the methodology developed will likely improve cultured skin graft material since it has ben reported that skin tissue with improved barrier properties increases the efficacy of such grafts. ..
- Amylase Binding Streptococci Dental Plaque and CariesFrank Scannapieco; Fiscal Year: 2007..mutans made to express AbpA show altered colonization and/or cariogenic abilities. Integration of in vitro with in vivo studies is crucial for mechanistic understanding of Dental plaque formation. ..
- Super-persistent cells and the paradox of untreatable infectionsKim Lewis; Fiscal Year: 2009..Our findings are likely to change the way we view infectious diseases and will provide rational approaches for discovering drugs that completely eradicate the infection. ..
- SCREEN DEVELOPMENT FOR ANTIMICROBIAL PRODRUGSKim Lewis; Fiscal Year: 2007....
- NOVEL METHODS FOR DISCOVERY OF ANTI-MICROBIALSKim Lewis; Fiscal Year: 2005..Determination of chemical structure will be performed by a combination of MS and NMR methods. ..
- A GENOMICS APPROACH TO DRUG TOLERANCEKim Lewis; Fiscal Year: 2009....
- Clinical Models Workshop:Remin-Demin, Precavity, CariesGeorge Stookey; Fiscal Year: 2005..The meeting will be held on July 3-5, 2005 in the Downtown Marriott Hotel in Indianapolis, Indiana, immediately prior to the annual ORCA (European Organization for Caries Research) meeting. ..
- NATURAL SUBSTRATES AND INHIBITORS OF MICROBIAL MDR PUMPSKim Lewis; Fiscal Year: 2002..MDR inhibitors will potentiate the action of conventional antibiotics, aiding eradication of multidrug resistant human pathogens. ..
- Oral Health and Ventilator Associated PneumoniaFrank Scannapieco; Fiscal Year: 2006..abstract_text> ..
- Optically enhanced dental sealants to indicate placement and material conditionGeorge Stookey; Fiscal Year: 2006..3) An optically doped sealant combines the efficacy advantages of a clear sealant with the visibility advantages of an opaque sealant. ..
