dental amalgam

Summary

Summary: An alloy used in restorative dentistry that contains mercury, silver, tin, copper, and possibly zinc.

Top Publications

  1. ncbi Adverse health effects related to mercury exposure from dental amalgam fillings: toxicological or psychological causes?
    J Bailer
    Department of Clinical Psychology, Central Institute of Mental Health, Mannheim, Germany
    Psychol Med 31:255-63. 2001
  2. ncbi Amalgam-contact hypersensitivity lesions and oral lichen planus
    Martin H Thornhill
    Department of Dental Diagnostic Science, University of Texas Health Science Center San Antonio, 78229 3900, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:291-9. 2003
  3. doi 12-year survival of composite vs. amalgam restorations
    N J M Opdam
    College of Dental Science, Department of Preventive and Restorative Dentistry, Radboud University Nijmegen Medical Centre, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    J Dent Res 89:1063-7. 2010
  4. ncbi Oral lichenoid reactions associated with amalgam: improvement after amalgam removal
    A Dunsche
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, Germany
    Br J Dermatol 148:70-6. 2003
  5. ncbi LTT-MELISA is clinically relevant for detecting and monitoring metal sensitivity
    Elizabeth Valentine-Thon
    Laboratory Center Bremen, Bremen, Germany
    Neuro Endocrinol Lett 27:17-24. 2006
  6. doi Biomonitoring of DNA damage in peripheral blood lymphocytes of subjects with dental restorative fillings
    Angela Di Pietro
    Department of Hygiene, Public Health and Preventive Medicine, University of Messina, Italy
    Mutat Res 650:115-22. 2008
  7. ncbi Neurobehavioral effects of dental amalgam in children: a randomized clinical trial
    Timothy A DeRouen
    Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195, USA
    JAMA 295:1784-92. 2006
  8. pmc Changes in health complaints after removal of amalgam fillings
    T T Sjursen
    Department of Clinical Dentistry, University of Bergen, Bergen, Norway
    J Oral Rehabil 38:835-48. 2011
  9. pmc Dental amalgam and psychosocial status: the New England Children's Amalgam Trial
    D C Bellinger
    Harvard Medical School, Harvard School of Public Health, Children s Hospital, Boston, MA, USA
    J Dent Res 87:470-4. 2008
  10. ncbi Release of mercury from dental amalgam and its influence on salivary antioxidant activity
    M Pizzichini
    Department of Biomedical Sciences, University of Siena, Italy
    Sci Total Environ 284:19-25. 2002

Detail Information

Publications298 found, 100 shown here

  1. ncbi Adverse health effects related to mercury exposure from dental amalgam fillings: toxicological or psychological causes?
    J Bailer
    Department of Clinical Psychology, Central Institute of Mental Health, Mannheim, Germany
    Psychol Med 31:255-63. 2001
    ..Thus, a psychosomatic aetiology of the complaints should be considered and psychological factors contributing to their aetiology should be identified...
  2. ncbi Amalgam-contact hypersensitivity lesions and oral lichen planus
    Martin H Thornhill
    Department of Dental Diagnostic Science, University of Texas Health Science Center San Antonio, 78229 3900, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:291-9. 2003
    ..The purpose of this study was to investigate the relationship between amalgam restorations and oral lichen planus...
  3. doi 12-year survival of composite vs. amalgam restorations
    N J M Opdam
    College of Dental Science, Department of Preventive and Restorative Dentistry, Radboud University Nijmegen Medical Centre, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    J Dent Res 89:1063-7. 2010
    ..Large composite restorations showed a higher survival in the combined population and in the low-risk group. For three-surface restorations in high-risk patients, amalgam showed better survival...
  4. ncbi Oral lichenoid reactions associated with amalgam: improvement after amalgam removal
    A Dunsche
    Department of Oral and Maxillofacial Surgery, University of Kiel, Arnold Heller Str 16, Germany
    Br J Dermatol 148:70-6. 2003
    The pathogenetic relationship between oral lichenoid reactions (OLR) and dental amalgam fillings is still a matter of controversy.
  5. ncbi LTT-MELISA is clinically relevant for detecting and monitoring metal sensitivity
    Elizabeth Valentine-Thon
    Laboratory Center Bremen, Bremen, Germany
    Neuro Endocrinol Lett 27:17-24. 2006
    ..In addition, we determined the reproducibility of the assay and assessed its clinical relevance for detecting and monitoring hypersensitivity to metals...
  6. doi Biomonitoring of DNA damage in peripheral blood lymphocytes of subjects with dental restorative fillings
    Angela Di Pietro
    Department of Hygiene, Public Health and Preventive Medicine, University of Messina, Italy
    Mutat Res 650:115-22. 2008
    ....
  7. ncbi Neurobehavioral effects of dental amalgam in children: a randomized clinical trial
    Timothy A DeRouen
    Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195, USA
    JAMA 295:1784-92. 2006
    ..No randomized clinical trials have determined whether there are significant health risks associated with this low-level mercury exposure...
  8. pmc Changes in health complaints after removal of amalgam fillings
    T T Sjursen
    Department of Clinical Dentistry, University of Bergen, Bergen, Norway
    J Oral Rehabil 38:835-48. 2011
    ..The mechanisms behind this remain to be identified. Reduced exposure to dental amalgam, patient-centred treatment and follow-ups, and elimination of worry are factors that may have influenced the ..
  9. pmc Dental amalgam and psychosocial status: the New England Children's Amalgam Trial
    D C Bellinger
    Harvard Medical School, Harvard School of Public Health, Children s Hospital, Boston, MA, USA
    J Dent Res 87:470-4. 2008
    ..vapor cause emotional dysfunction, but it is uncertain whether the levels of exposure that result from having dental amalgam restorations do so...
  10. ncbi Release of mercury from dental amalgam and its influence on salivary antioxidant activity
    M Pizzichini
    Department of Biomedical Sciences, University of Siena, Italy
    Sci Total Environ 284:19-25. 2002
    b>Dental amalgam fillings are known to release significant amounts of mercury (Hg) in saliva which could represent a continuous source of oxidative damage to mouth tissues...
  11. ncbi Determination of mercury in blood, urine and saliva for the biological monitoring of an exposure from amalgam fillings in a group with self-reported adverse health effects
    Holger Zimmer
    Institute and Policlinic of Occupational and Social Medicine, University Hospital of Heidelberg, Heidelberg, Germany
    Int J Hyg Environ Health 205:205-11. 2002
    ..Mercury levels in saliva did not correlate with the concentrations in blood and urine, but merely with the number of amalgam fillings or of the filling surfaces. Mercury in saliva is therefore not recommended for a biological monitoring...
  12. doi Migration of mercury from dental amalgam through human teeth
    Hugh H Harris
    School of Chemistry, The University of Sydney, NSW 2006, Australia
    J Synchrotron Radiat 15:123-8. 2008
    ..Most importantly the detection of Hg in areas of the tooth that once contained an active bloodstream and in calculus indicates that both exposure pathways should be considered as significant...
  13. ncbi Oral lichen planus and dental materials: a case-control study
    Michael D Martin
    Department of Oral Medicine, School of Dentistry, University of Washington, Seattle, WA 98195, USA
    Contact Dermatitis 48:331-6. 2003
    ....
  14. ncbi Whole-body imaging of the distribution of mercury released from dental fillings into monkey tissues
    L J Hahn
    Department of Radiology, University of Calgary, Faculty of Medicine, Alberta, Canada
    FASEB J 4:3256-60. 1990
    ..The dental profession's advocacy of silver amalgam as a stable tooth restorative material is not supported by these findings...
  15. pmc The three modern faces of mercury
    Thomas W Clarkson
    Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Environ Health Perspect 110:11-23. 2002
    ..Mechanisms of action are discussed where possible. Key gaps in our current knowledge are identified from the points of view both of risk assessment and of mechanisms of action...
  16. ncbi Dental amalgam and mercury levels in autopsy tissues: food for thought
    Gianpaolo Guzzi
    Italian Association for Metals and Biocompatibility Research AIRMEB, Milan, Italy
    Am J Forensic Med Pathol 27:42-5. 2006
    ..On these same cadavers, all dental amalgam fillings (the most important source of inorganic mercury exposure in the general population, according to the ..
  17. ncbi Healing of oral lichenoid lesions after replacing amalgam restorations: a systematic review
    Y Issa
    University Dental Hospital of Manchester, England, UK
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:553-65. 2004
    ..We sought to systematically review the literature related to oral lichenoid lesions (OLLs) and amalgam restorations...
  18. ncbi Blood and urine mercury levels in adult amalgam patients of a randomized controlled trial: interaction of Hg species in erythrocytes
    S Halbach
    Institute of Toxicology, GSF Research Center for Environment and Health, Munich, Germany
    Environ Res 107:69-78. 2008
    Parts of the population are permanently exposed to low levels of Hg degrees and Hg(II) from dental amalgam. It was the aim (1) to investigate the internal exposure to amalgam-related mercury from the kinetics of inorganic Hg in plasma and ..
  19. ncbi Mercury release from dental amalgam restorations after magnetic resonance imaging and following mobile phone use
    S M J Mortazavi
    Department of Medical Physics, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
    Pak J Biol Sci 11:1142-6. 2008
    ..b>Dental amalgam restoration was performed for all 14 students...
  20. ncbi Dental amalgam fillings and the amount of organic mercury in human saliva
    J Leistevuo
    The National Public Health Institute, Antimicrobial Research Laboratory, Turku University, Turku, Finland
    Caries Res 35:163-6. 2001
    ..001) in subjects with dental amalgam fillings (n = 88) compared to the nonamalgam study groups (n = 43 and n = 56): log(e) (organic mercury) was ..
  21. pmc The association between serotonin transporter gene promoter polymorphism (5-HTTLPR), self-reported symptoms, and dental mercury exposure
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, Washington 98109 3598, USA
    J Toxicol Environ Health A 71:1318-26. 2008
    ..These findings suggest that within this restricted population increased symptoms of depression, anxiety, and memory are associated with the 5-HTTLPR polymorphism among both males and females...
  22. ncbi Memory functions in persons with dental amalgam
    K Dalen
    Department of Clinical Neuropsychology, University of Bergen, Jonas Liesvei 91, N 5009, Bergen, Norway
    J Dent 31:487-92. 2003
    Memory and psychophysiological variables in persons with self-reported reactions to dental amalgam (amalgam patients: N=26) and in persons without such symptoms (controls: N=21) were compared...
  23. ncbi Amalgam exposure and neurological function
    Albert Kingman
    Division of Clinical Research and Health Promotion, National Institute of Dental and Craniofacial Research, National Institutes of Health, 45 Center Drive, Room 4As 25U, Bethesda, MD 20892 6401, USA
    Neurotoxicology 26:241-55. 2005
    ..An assessment of exposure to dental amalgam fillings was added to the 1997-1998 health examination to investigate possible associations between amalgam ..
  24. ncbi Oral lichen planus and allergy to dental amalgam restorations
    Ronald Laeijendecker
    Department of Dermatology, Albert Schweitzer Hospital, Dordrecht, The Netherlands
    Arch Dermatol 140:1434-8. 2004
    ....
  25. doi A significant relationship between mercury exposure from dental amalgams and urinary porphyrins: a further assessment of the Casa Pia children's dental amalgam trial
    David A Geier
    Institute of Chronic Illnesses, Inc, Silver Spring, MD, USA
    Biometals 24:215-24. 2011
    ..trial that was designed to evaluate the potential health consequences of prolonged exposure to Hg from dental amalgam fillings (the parent study)...
  26. ncbi Improved orthodontic bonding to silver amalgam. Part 2. Lathe-cut, admixed, and spherical amalgams with different intermediate resins
    T Buyukyilmaz
    Department of Orthodontics, Dental Faculty, Blindern, Oslo, Norway
    Angle Orthod 68:337-44. 1998
    ..05). The implications of these findings are discussed in relationship to clinical experience bonding orthodontic attachments to large amalgam restorations in posterior teeth...
  27. ncbi A new multipurpose dental adhesive for orthodontic use: an in vitro bond-strength study
    D Harari
    Department of Orthodontics, Hebrew University Hadassah Faculty of Dental Medicine, Jerusalem, Israel
    Am J Orthod Dentofacial Orthop 118:307-10. 2000
    ..It is suggested that HQB can be applied for orthodontic use, but further clinical studies are required to evaluate its efficacy...
  28. ncbi Mercury vapor release from dental amalgam after laser treatment
    T Pioch
    Department of Restorative Dentistry, University of Heidelberg, Germany
    Eur J Oral Sci 106:600-2. 1998
    ..With the solid state lasers tested, however, the Hg vapor measurements taken indicated that pulses applied to amalgam cause a substantially increased release of Hg vapor. This vapor may contribute to the patient's total mercury exposure...
  29. ncbi Oral lichenoid lesions related to dental restorative materials
    Y Issa
    Turner School of Dentistry, University of Manchester, UK
    Br Dent J 198:361-6; disussion 549; quiz 372. 2005
    ..To determine the effectiveness of replacing restorations considered to be the cause of an oral lichenoid lesion (oral lichenoid reaction)(OLL)...
  30. ncbi Magnetic susceptibility and electrical conductivity of metallic dental materials and their impact on MR imaging artifacts
    Jana Starcuková
    Institute of Scientific Instruments of the ASCR, v v i, Academy of Sciences of the Czech Republic, Kralovopolska 147, 612 64 Brno, Czech Republic
    Dent Mater 24:715-23. 2008
    ....
  31. doi Stressful negative life events and amalgam-related complaints
    Anna Sundström
    Centre for Population Studies Ageing and Living Conditions Programme, Umea University, Umea, Sweden
    Community Dent Oral Epidemiol 39:12-8. 2011
    ..The role of stressful life events in the onset of self-reported amalgam-related complaints is unclear. The aim of this study was to examine the relationship between life events and amalgam-related complaints...
  32. doi Shear bond strength of brackets bonded to amalgam with different intermediate resins and adhesives
    Derya Germec
    Department of Orthodontics, Yeditepe University, Istanbul, Turkey
    Eur J Orthod 31:207-12. 2009
    ..Bond failure occurred at the amalgam-adhesive interface regardless of the adhesive system and without damage to the amalgam restoration...
  33. ncbi The role of histopathological characteristics in distinguishing amalgam-associated oral lichenoid reactions and oral lichen planus
    Martin H Thornhill
    Department of Oral and Maxillofacial Medicine and Surgery, University of Sheffield School of Clinical Dentistry, UK
    J Oral Pathol Med 35:233-40. 2006
    ..To identify histological features that distinguish amalgam-associated oral lichenoid reactions (AAOLR) from oral lichen planus (OLP)...
  34. pmc Immune function effects of dental amalgam in children: a randomized clinical trial
    Bruce J Shenker
    Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Dent Assoc 139:1496-505. 2008
    b>Dental amalgam is a widely used restorative material containing 50 percent elemental mercury that emits mercury vapor...
  35. doi Mercury exposure and risks from dental amalgam in the US population, post-2000
    G M Richardson
    SNC Lavalin Environment, Suite 110, 20 Colonnade Road, Ottawa, ON Canada
    Sci Total Environ 409:4257-68. 2011
    b>Dental amalgam is 50% metallic mercury (Hg) by weight and Hg vapour continuously evolves from in-place dental amalgam, causing increased Hg content with increasing amalgam load in urine, faeces, exhaled breath, saliva, blood, and various ..
  36. ncbi Lichenoid reaction associated to amalgam restoration
    Juan Jose Segura-Egea
    Dpto de Estomatologia, Facultad de Odontologia, Universidad de Sevilla
    Med Oral Patol Oral Cir Bucal 9:423-4; 421-3. 2004
    ..a delayed, type IV, cell mediated immune response to mercury or one of the other constituents of the dental amalgam. We report a case of oral lichenoid reaction associated to amalgam restoration...
  37. ncbi A method of eliminating streak artifacts from metallic dental restorations in CTs of head and neck cancer patients
    O Odlum
    Faculty of Dentistry, University of Manitoba, 789 Bannatyne Avenue, Winnipeg, Manitoba, Canada R3E 0W2
    Spec Care Dentist 21:72-4. 2001
    ..The substitution of radiolucent for metallic restorations in special cases should be considered as a solution to CT dental artifact problems...
  38. ncbi The clinicopathological characteristics of oral lichen planus and its relationship with dental materials
    P Lopez-Jornet
    Oral Medicine, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain
    Contact Dermatitis 51:210-1. 2004
    ..The histological variables showed no statistically significant differences between the groups...
  39. doi Oral lichenoid reaction associated with tin component of amalgam restorations: a case report
    Vivek Aggarwal
    Department of Dental Surgery, Safdarjung Hospital, New Delhi, India
    Am J Dermatopathol 32:46-8. 2010
    ..The clinician should be aware of all possible pathological etiologies of white lesions. If there is any doubt about the nature or management of an unusual oral lesion, referral to appropriate specialists is mandatory...
  40. ncbi Effects of surface treatment on orthodontic bonding to amalgam
    Jonathan W Skilton
    School of Dental Science, The University of Melbourne, Melbourne, Victoria, Australia
    Aust Orthod J 22:59-66. 2006
    ..This study aimed to compare the shear bond strengths of metal brackets bonded to amalgam surfaces...
  41. ncbi Maternal and neonatal hair mercury concentrations: the effect of dental amalgam
    S W Lindow
    Department of Obstetrics and Gynaecology, Hull Maternity Hospital, UK
    BJOG 110:287-91. 2003
    To evaluate maternal and fetal hair mercury levels in relation to the placement of dental amalgam tooth restorations.
  42. ncbi A dose-effect analysis of children's exposure to dental amalgam and neuropsychological function: the New England Children's Amalgam Trial
    David C Bellinger
    Children s Hospital, Boston, MA, USA
    J Am Dent Assoc 138:1210-6. 2007
    ..10-year-old children that compared the neuropsychological outcomes of those whose caries were restored using dental amalgam with the outcomes of those those whose caries were restored using mercury-free resin-based composite...
  43. ncbi Maternal-fetal distribution of mercury (203Hg) released from dental amalgam fillings
    M J Vimy
    Department of Medicine, Faculty of Medicine, University of Calgary, Alberta, Canada
    Am J Physiol 258:R939-45. 1990
    In humans, the continuous release of Hg vapor from dental amalgam tooth restorations is markedly increased for prolonged periods after chewing...
  44. ncbi Compressive strength of some polyalkenoates with or without dental amalgam alloy incorporation
    H M Beyls
    Department of Conservative Dentistry and Pedodontics, University of Ghent
    Dent Mater 7:151-4. 1991
    ..restorative materials with that of glass ionomers reinforced by the addition of ceramic-coated silver or dental amalgam alloy particles to the aluminosilicate glass powder...
  45. ncbi A 7-year prospective quasi-experimental study of the effects of removing dental amalgam in 76 self-referred patients compared with 146 controls
    Per Nerdrum
    Oslo University College, Pilestredet 56, 0167 Oslo, Norway
    J Psychosom Res 57:103-11. 2004
    b>Dental amalgam has been suggested to cause long-term physical and mental problems...
  46. ncbi Decrease of trace elements in erythrocytes and plasma after removal of dental amalgam and other metal alloys
    Peter Frisk
    Foundation for Metal Biology, Uppsala, Sweden
    Biol Trace Elem Res 113:247-59. 2006
    ..was to determine the concentration changes of 13 elements in erythrocytes and plasma after the removal of dental amalgam and other metal alloys...
  47. doi Biomonitoring of mercury in patients with complaints attributed to dental amalgam, healthy amalgam bearers, and amalgam-free subjects: a diagnostic study
    Dieter Melchart
    Technical University Munich, Munich, Germany
    Clin Toxicol (Phila) 46:133-40. 2008
    To investigate the suitability of measurements of mercury (Hg) concentration as a means of identifying patients with health complaints attributed to dental amalgam.
  48. doi Predictors of treatment outcomes after removal of amalgam fillings: associations between subjective symptoms, psychometric variables and mercury levels
    Wolfgang Weidenhammer
    Centre for Complementary Medicine Research, Internal Medicine II, Technical University Munich, Munich, Germany
    Community Dent Oral Epidemiol 38:180-9. 2010
    ..This analysis aimed to study predictors of different treatment outcomes and associations between subjective symptoms, psychometric variables and mercury levels in patients who subjectively attributed their health problems to dental amalgam.
  49. ncbi Diagnostic value of a chelating agent in patients with symptoms allegedly caused by amalgam fillings
    J S Vamnes
    University of Bergen, Department of Odontology Dental Biomaterials, Norway
    J Dent Res 79:868-74. 2000
    ..21 healthy controls with amalgam fillings; 20 patients who claimed symptoms of "mercury poisoning" from dental amalgam; and 20 patients who had amalgam fillings removed because of such symptoms...
  50. pmc Renal effects of dental amalgam in children: the New England children's amalgam trial
    Lars Barregard
    Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital and Academy, Gothenburg, Sweden
    Environ Health Perspect 116:394-9. 2008
    Mercury is nephrotoxic and dental amalgam is a source of mercury exposure.
  51. ncbi The effect of hydrogen peroxide concentration on metal ion release from dental amalgam
    S K al-Salehi
    Centre for Biomaterials and Tissue Engineering, Department of Adult Dental Care, School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield S10 2TA, UK
    J Dent 35:172-6. 2007
    The aim of this study was to investigate the effect of hydrogen peroxide (HP) concentration on metal ion release from dental amalgam.
  52. ncbi A 30-year follow-up of residual effects on New Zealand School Dental Nurses, from occupational mercury exposure
    Linda Jones
    School of Psychology, Massey University, Wellington, New Zealand
    Hum Exp Toxicol 26:367-74. 2007
    ..In general, the study suggests that acute symptoms from mercury exposure may be reversible, while some residual health effects may be becoming more of a concern with the women's increasing age...
  53. ncbi Neuropsychological and renal effects of dental amalgam in children: a randomized clinical trial
    David C Bellinger
    Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, Mass, USA
    JAMA 295:1775-83. 2006
    ..No randomized trials have been published that address the concern that inhalation of mercury vapor released by amalgam dental restorations causes adverse health effects...
  54. ncbi Dental amalgam as one of the risk factors in autoimmune diseases
    Jirina Bartova
    Institute of Dental Research, lst Medical Faculty, Charles University and General Faculty Hospital Prague, Vinohradská 48, 120 60 Prague 2, Czech Republic
    Neuro Endocrinol Lett 24:65-7. 2003
    Experimental and clinical data published recently show that dental amalgam can give rise to undesirable immunological responses in susceptible individuals...
  55. ncbi The effect of tin in the Ag-Hg phase of dental amalgam on dissolution of mercury
    M Marek
    School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, USA
    Dent Mater 13:353-9. 1997
    The aim of this study was to determine the relationship between the tin content in the gamma 1 phase of dental amalgam and the kinetics of mercury dissolution.
  56. doi Mercury pink exanthem after dental amalgam placement
    P D Pigatto
    J Eur Acad Dermatol Venereol 22:377-8. 2008
  57. ncbi Four years of clinical experience with an adverse reaction unit for dental biomaterials
    Jan Sverre Vamnes
    Department of Odontology, Dental Biomaterials, University of Bergen, Norway
    Community Dent Oral Epidemiol 32:150-7. 2004
    ..We describe the function of, and results from, the Norwegian National Dental Biomaterials Adverse Reaction Unit after 4 years of activity from 1993 to 1997...
  58. ncbi Removal of dental amalgam and other metal alloys supported by antioxidant therapy alleviates symptoms and improves quality of life in patients with amalgam-associated ill health
    Ulf Lindh
    Department of Oncology, Radiology and Clinical Immunology, Rudbeck Laboratory, SE 751 85 Uppsala, Sweden
    Neuro Endocrinol Lett 23:459-82. 2002
    The purpose of this study was to evaluate treatment of patients suffering from chronic ill health with a multitude of symptoms associated with metal exposure from dental amalgam and other metal alloys.
  59. ncbi Patients' choice of dental treatment following examination at a specialty unit for adverse reactions to dental materials
    Gunvor Bentung Lygre
    University of Bergen, Norway
    Acta Odontol Scand 62:258-63. 2004
    ..It appears that the examination at the Dental Biomaterials Adverse Reaction Unit is one of several inputs that influence a person's decision to replace dental materials...
  60. ncbi The release of mercury from dental amalgam and potential neurotoxicological effects
    M Sweeney
    Hard Tissue Research Group, Glasgow Dental Hospital and School, University of Glasgow, 378 Sauchiehall Street, Scotland Glasgow G2 3JZ, UK
    J Dent 30:243-50. 2002
    ..The aim of this study was to estimate the amount of mercury released into both air and saliva from fresh and aged, abraded amalgam discs and then investigate neurotoxic effects of inorganic mercury upon sensory neuronal cultures...
  61. pmc The chemical forms of mercury in aged and fresh dental amalgam surfaces
    Graham N George
    Department of Geological Sciences, University of Saskatchewan, 114 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada
    Chem Res Toxicol 22:1761-4. 2009
    Mercury-containing dental amalgam is known to be a source of human exposure to mercury. We have explored the use of electron yield Hg L(III) X-ray absorption spectroscopy to characterize the chemical nature of dental amalgam surfaces...
  62. ncbi Mercury amalgam dental fillings: an epidemiologic assessment
    Michael N Bates
    Division of Environmental Health Sciences, School of Public Health, 140 Warren Hall, University of California, Berkeley, CA 94720 7360, USA
    Int J Hyg Environ Health 209:309-16. 2006
    b>Dental amalgam fillings containing approximately 50% mercury have been used for almost 200 years and have been controversial for almost the same time. Allegations of effects caused by amalgams have involved many diseases...
  63. ncbi Has dental amalgam been torpedoed and sunk?
    Derek W Jones
    J Dent Res 87:101-2. 2008
  64. ncbi Number of amalgam tooth fillings in relation to subjectively experienced symptoms in a study of Swedish women
    M Ahlqwist
    Department of Oral Radiology, School of Dentistry, , Sweden
    Community Dent Oral Epidemiol 16:227-31. 1988
    ..This study does not support the view of a correlation between amalgam fillings and symptoms and complaints, at least not on a population level...
  65. ncbi The role of environmental factors in autoimmune thyroiditis
    Monika Hybenova
    Institute of Immunology and Microbiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 31:283-9. 2010
    ..The important source of mercury is dental amalgam. Replacement of amalgam in mercury-allergic subjects resulted in improvement of health in about 70% of ..
  66. ncbi Mercury inductions in persons with subjective symptoms alleged to dental amalgam fillings
    R Stromberg
    Department of Public Health Sciences, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Eur J Oral Sci 107:208-14. 1999
    This study was carried out to determine whether health disturbances alleged to mercury release from dental amalgam fillings, i.e. "amalgam disease", may be caused by an increased sensitivity to mercury (Hg)...
  67. ncbi Dental amalgam restorations: daily mercury dose and biocompatibility
    Richard J Mitchell
    Department of Oral Health Practice, Division of Restorative Dentistry, College of Dentistry, University of Kentucky, Lexington, Kentucky 40536 0027, USA
    J Long Term Eff Med Implants 15:709-21. 2005
    ..Along the way, the history and chemistry of dental amalgam are outlined...
  68. ncbi Treatment of health complaints attributed to amalgam
    D Melchart
    Centre for Complementary Medicine Research, Internal Medicine II, Technische Universitat Munchen, Munich, Germany
    J Dent Res 87:349-53. 2008
    ..The individuals were randomly assigned either to removal of dental amalgam only (removal group), or removal in combination with a "biological detoxification" therapy with high doses of ..
  69. ncbi A follow-up study of patients with subjective symptoms related to dental materials
    Gunvor Bentung Lygre
    Dental Biomaterials Adverse Reaction Unit, UNIFOB, University of Bergen, Bergen, Norway
    Community Dent Oral Epidemiol 33:227-34. 2005
    ....
  70. ncbi Changed clinical chemistry pattern in blood after removal of dental amalgam and other metal alloys supported by antioxidant therapy
    Peter Frisk
    Foundation for Metal Biology, Uppsala, Sweden
    Biol Trace Elem Res 120:163-70. 2007
    This study aimed to investigate a possible connection between removal of dental amalgam restorations supported by antioxidant therapy and indicative changes of clinical chemistry parameters...
  71. ncbi Dental amalgam and multiple sclerosis: a systematic review and meta-analysis
    Kevin K Aminzadeh
    Center for Clinical Epidemiology and Evaluation, Vancouver Hospital, Vancouver, Canada
    J Public Health Dent 67:64-6. 2007
    ..To explore and quantify the association between amalgam restorations and MS we have conducted a systematic review and meta-analysis of the literature...
  72. ncbi Mercury recovery in situ of four different dental amalgam separators
    Lars D Hylander
    Department of Earth Sciences, Air and Water Science, Uppsala University, Villavägen 16, S 752 36 Uppsala, Sweden
    Sci Total Environ 366:320-36. 2006
    Amalgam separators are used to physically remove dental amalgam from waste water in dental clinics. They are thereby supposed to reduce mercury (Hg) emissions to the municipal waste water system to acceptable levels...
  73. ncbi Multidisciplinary examination of patients with illness attributed to dental fillings
    S Langworth
    Department of Public Health Sciences, Division of Occupational Medicine, Karolinska Hospital and Karolinska Institutet, Stockholm, Sweden
    J Oral Rehabil 29:705-13. 2002
    ..Patients were examined by a dentist (n 428), a physician (n 379), and a psychologist (n 360). Sixty-nine per cent were women and 31% men; the mean patient age was 46 years...
  74. ncbi The potential adverse health effects of dental amalgam
    Amy M Brownawell
    Life Sciences Research Office, Bethesda, Maryland 20814 3998, USA
    Toxicol Rev 24:1-10. 2005
    ..public concern about the potential health effects of exposure to mercury vapour (Hg(0)) released from dental amalgam restorations...
  75. ncbi Risks of dental amalgam in children
    Paolo D Pigatto
    JAMA 296:1461; author reply 1461. 2006
  76. ncbi Placental transfer of mercury in pregnant rats which received dental amalgam restorations
    Yoshifumi Takahashi
    Department of Dental Material Science, School of Dentistry, Aichi Gakuin University, 1 100 Kusumoto cho, Chikusa ku, Nagoya 464 8650, Japan
    Toxicology 185:23-33. 2003
    ..The results of the present study demonstrated that mercury vapor released from the amalgam fillings in pregnant rats was distributed to maternal and fetal organs in dose-dependent amounts of the amalgam fillings...
  77. ncbi [10 years of observation by public health offices in Baden-Württemberg--assessment of human biomonitoring for mercury due to dental amalgam fillings and other sources]
    T Gabrio
    Landesgesundheitsamt Baden Württemberg, Stuttgart
    Gesundheitswesen 65:327-35. 2003
    ..The decrease in the body burden of mercury as a result of the declining usage of dental amalgam fillings, was been verified...
  78. pmc Evaluation of the mercury exposure of dental amalgam patients by the Mercury Triple Test
    G Hansen
    Laboratoire d Hygiène du Milieu et de Surveillance Biologique, Laboratoire National de Santé, Luxembourg
    Occup Environ Med 61:535-40. 2004
    ..To establish and analyse reference data for the mercury burden of patients with and without amalgam fillings...
  79. ncbi Changes in surface levels of mercury, silver, tin, and copper of dental amalgam treated with carbamide peroxide and hydrogen peroxide in vitro
    I Rotstein
    Department of Endodontics, Hebrew University Hadassah Faculty of Dental Medicine, Jerusalem, Israel
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83:506-9. 1997
    ....
  80. ncbi Revised and new reference values for arsenic, cadmium, lead, and mercury in blood or urine of children: basis for validation of human biomonitoring data in environmental medicine
    Micheal Wilhelm
    Department of Hygiene, Social and Environmental Medicine, Ruhr University Bochum, Bochum, Germany
    Int J Hyg Environ Health 209:301-5. 2006
    ..5 microg/l) were confirmed. The following reference values were lowered: for lead in blood from 60 to 50 microg/l, for mercury in whole blood from 1.5 to 1.0 microg/l and for mercury in urine from 1.4 to 0.7 microg/l...
  81. ncbi The use of amalgam in pediatric dentistry
    Anna B Fuks
    Department of Pediatric Dentistry, Hebrew University, Hadassah School of Dental Medicine, Jerusalem, Israel
    Pediatr Dent 24:448-55. 2002
    ..Currently, amalgam demonstrates the best clinical success for Class II restorations that extend beyond the proximal line angles of permanent molars...
  82. ncbi Urinary mercury in people living near point sources of mercury emissions
    Lars Barregard
    Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital and Academy, Goteborg University, Goteborg, Sweden
    Sci Total Environ 368:326-34. 2006
    ..This was the case also when the comparison was restricted to subjects with no dental amalgam and low fish consumption...
  83. ncbi Anaerobic microflora under Class I and Class II composite and amalgam restorations
    Christian Splieth
    Department of Restorative Dentistry, Periodontology, and Pediatric Dentistry, University of Greifswald, Greifswald, Germany
    Quintessence Int 34:497-503. 2003
    ..The aim of this pilot study was to determine and compare the microbial spectrum under composite and amalgam restorations with special attention to the anaerobic flora...
  84. ncbi Dental workplace exposure and effect on fertility
    J E Dahl
    NIOM Scandinavian Institute of Dental Materials, Haslum, Norway
    Scand J Work Environ Health 25:285-90. 1999
    ..This study assessed occupational exposure in dental surgeries on the basis of the reported use of dental materials and techniques and applied waiting-time-to-pregnancy methodology to study fertility in relation to the occupational exposure...
  85. ncbi Health effects of dental amalgam exposure: a retrospective cohort study
    Michael N Bates
    Institute of Environmental Science and Research Ltd ESR, PO Box 50 348, Porirua, New Zealand
    Int J Epidemiol 33:894-902. 2004
    Whether dental amalgam fillings (containing mercury) are hazardous is a long-standing issue, with few epidemiological investigations...
  86. ncbi Mercury uptake and kinetics after ingestion of dental amalgam
    E af Geijersstam
    Dept. of Basic Oral Sciences, School of Dentistry, Karolinska Institutet, Huddinge, Sweden
    J Dent Res 80:1793-6. 2001
    ..The absorbed fraction of the administered dose was estimated to be about 0.04%. It is concluded that the G-1 uptake of Hg is of quantitative importance during dental treatment...
  87. ncbi The use of dental amalgam in pediatric dentistry: review of the literature
    J W Osborne
    University of Colorado Health Science Center, Denver, USA
    Pediatr Dent 24:439-47. 2002
    b>Dental amalgam is widely used as a restorative material even though it is not esthetic and there has been extensive anti-amalgam rhetoric...
  88. ncbi Impact of nocturnal bruxism on mercury uptake from dental amalgams
    G Isacsson
    Orofacial Pain Clinic, Postgraduate Dental Education Centre, Orebro County Council, Sweden
    Eur J Oral Sci 105:251-7. 1997
    The mercury (Hg) release from dental amalgam fillings increases by mechanical stimulation...
  89. ncbi Reasons for replacement of restorations in permanent teeth in general dental practice
    I A Mjor
    JHMHSC, Gainesville, FL 32610 0415, USA
    Int Dent J 50:361-6. 2000
    ..The analysis of reasons for the replacement of 9,805 amalgam, composite, glass ionomer, resin modified glass ionomer and 'other' restorations in permanent teeth in general dental practice...
  90. ncbi Mercury and silver in saliva from subjects with symptoms self-related to amalgam fillings
    G B Lygre
    Dental Biomaterials Adverse Reaction Unit, University of Bergen, Norway
    Clin Oral Investig 3:216-8. 1999
    The amount of mercury released into saliva from dental amalgam fillings is currently being debated. Mercury enters saliva as vapor, ions and particles of amalgam...
  91. doi Influence of restorative technique on the biomechanical behavior of endodontically treated maxillary premolars. Part II: strain measurement and stress distribution
    Paulo Vinicius Soares
    Biomechanical Group, Dentistry and Dental Materials, School of Dentistry, Federal University of Uberlandia, Minas Gerais, Brazil
    J Prosthet Dent 99:114-22. 2008
    ..Unresolved controversy exists concerning the preferred cavity design and restorative technique used to restore endodontically treated maxillary premolars to minimize strain and improve stress distribution under occlusal load...
  92. ncbi Bacterial penetration of restored cavities
    S Zivkovic
    Clinic for Conservative Dentistry and Endodontics, Faculty of Stomatology, University of Belgrade, Yugoslavia
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91:353-8. 2001
    ..The bacterial penetration test showed that the use of restorative material does not entirely eliminate microleakage...
  93. ncbi Fracture resistance of endodontically treated teeth restored with combined composite-amalgam restorations
    Selly Geiger
    Department of Restorative Dentistry, The Maurice and Gabriella Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel
    Quintessence Int 39:e58-62. 2008
    ..To evaluate the resistance to fracture of endodontically treated teeth restored with combined composite-amalgam restorations in comparison to all-amalgam restorations...
  94. ncbi Remaining challenges with Class II resin-based composite restorations
    Gordon J Christensen
    CRA Foundation, 3707 N Canyon Road, Provo, UT 84604, USA
    J Am Dent Assoc 138:1487-9. 2007
  95. ncbi Marginal adaptation of amalgam and resin composite restorations in Class II conservative preparations
    W V Duncalf
    University Dental Hospital of Manchester, Higher Cambridge Street, Manchester M15 6FH, England
    Quintessence Int 32:391-5. 2001
    ....
  96. ncbi Effectiveness of glass-ionomer (ART) and amalgam restorations in the deciduous dentition: results after 3 years
    D Taifour
    Regional WHO Demonstration, Training and Research Centre for Oral Health, Damascus, Syria
    Caries Res 36:437-44. 2002
    ..It is recommended to select the ART approach to complement the other activities of the school oral health programme...
  97. ncbi Clinical evaluation of a compomer and an amalgam primary teeth class II restorations: a 2-year comparative study
    Katerina Kavvadia
    Department of Pediatric Dentistry, University of Athens, Greece
    Pediatr Dent 26:245-50. 2004
    ..This study was performed to compare the clinical performance between the compomer F2000 and amalgam Dispersalloy in Class II restorations in primary molars over a 2-year period...
  98. ncbi On material choice and fracture susceptibility of restored teeth: an asymptotic stress analysis approach
    Bill Kahler
    School of Dentistry, University of Adelaide, SA 5005, Australia
    Dent Mater 22:1109-14. 2006
    ..The purpose of this study was to specifically examine aspects of the material choice holding other factors constant...
  99. ncbi Amalgam repair: evaluation of bond strength and microleakage
    F Ozer
    Selcuk University, Faculty of Dentistry, Department of Operative Dentistry, Konya, Turkiye
    Oper Dent 27:199-203. 2002
    ..PF, MB, 3MOLC and FB performed better at the amalgam "repair" interface. The A+LB2V+A group showed no microleakage at both the occlusal and gingival test regions...
  100. ncbi Suitability of a shear punch test for dental restorative materials
    R Nomoto
    Dental Materials Science Unit, Department of Restorative Dentistry, The Dental School, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4BW, UK
    Dent Mater 17:415-21. 2001
    ..However, for some glass ionomer and amalgam specimens radial cracking was also observed. SIGNIFICANCE: This study suggests that the simple test described is suitable for standardization purposes...
  101. doi Effect of erosive pH cycling on different restorative materials and on enamel restored with these materials
    Luciana Fávaro Francisconi
    Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of Sao Paulo, Bauru SP, Brazil
    Oper Dent 33:203-8. 2008
    ..In conclusion, there were only subtle differences among the materials, and these differences were not able to protect the surrounding enamel from erosion...

Research Grants80

  1. Im/Miscible Adhesive/Dentin Interface: Structure/Mechanic
    Paulette Spencer; Fiscal Year: 2009
    ..This emphasis on replacement therapy is expected to grow as the public's concern regarding mercury and dental amalgam forces dentists to select alternative materials, e.g. composite...
  2. Im/Miscible Adhesive/Dentin Interface: Structure/Mechanic
    Paulette Spencer; Fiscal Year: 2010
    ..This emphasis on replacement therapy is expected to grow as the public's concern regarding mercury and dental amalgam forces dentists to select alternative materials, e.g. composite...
  3. EVALUATION OF MERCURY RELEASE FROM DENTAL AMALGAMS
    Toru Okabe; Fiscal Year: 2003
    ..to determine the mechanism by which changes in the formulation of the alloy reduce mercury (Hg) release from dental amalgam. A series of alloys will be prepared to test specific hypotheses about the effect of palladium (Pd) additions, ..
  4. DISSOLUTION OF MERCURY FROM DENTAL AMALGAMS
    Miroslav Marek; Fiscal Year: 2001
    b>Dental amalgam remains the most common direct filling material for restoration of tooth structure. The presence of mercury in a material used in the oral cavity has raised some concerns...
  5. Determinants of the Durability of Resin-Dentin Bonds
    David Pashley; Fiscal Year: 2006
    ..This should provide important new insight into designing more durable resin-dentin bonds that can justify the placement of resin-based posterior composites. ..
  6. HEALTH EFFECTS OF DENTAL AMALGAMS IN CHILDREN
    Sonja McKinlay; Fiscal Year: 2005
    ..introduction 150 years ago, but-until recently it has been generally assumed that the exposure to mercury from dental amalgam is limited to the acute placement phase...
  7. CERAMIC WHISKER REINFORCEMENT OF DENTAL COMPOSITE RESINS
    HUAKUN XU; Fiscal Year: 2002
    Concerns about mercury in dental amalgam have created a need to extend the use of composite resins to posterior applications...
  8. Im/Miscible Adhesive/Dentin Interface: Structure/Mechanic
    Paulette Spencer; Fiscal Year: 2007
    DESCRIPTION: If composite resins are to be considered a viable alternative to Dental amalgam, the durability of the dentin/adhesive (d/a) bond must be improved...
  9. Mercury Vapor from Amalgam and Methylmercury Co-Exposure on Neurodevelopment
    Gene Watson; Fiscal Year: 2009
    Mercury (Hg) vapor and monomethylmercury (MeHg) are separately potent neurotoxins. Dental amalgam restorations, which are composed of approximately 50% metallic Hg, are the principal source of human exposure to Hg vapor, while most ..
  10. Mercury Vapor from Amalgam and Methylmercury Co-Exposure on Neurodevelopment
    GENE E WATSON; Fiscal Year: 2010
    Mercury (Hg) vapor and monomethylmercury (MeHg) are separately potent neurotoxins. Dental amalgam restorations, which are composed of approximately 50% metallic Hg, are the principal source of human exposure to Hg vapor, while most ..
  11. Mercury Vapor from Amalgam and Methylmercury Co-Exposure on Neurodevelopment
    Gene Watson; Fiscal Year: 2007
    Mercury (Hg) vapor and monomethylmercury (MeHg) are separately potent neurotoxins. Dental amalgam restorations, which are composed of approximately 50% metallic Hg, are the principal source of human exposure to Hg vapor, while most ..
  12. ENHANCED DENTAL AMALGAM TRAP
    CRAIG TURCHI; Fiscal Year: 2003
    ..ADA Technologies will utilize its network of partners and experience in dental waste treatment and equipment manufacturing to bring this enhanced trap rapidly to the marketplace. ..
  13. THERMALLY INDUCED CHANGES IN DENTAL PORCELAIN EXPANSION
    JOHN MACKERT; Fiscal Year: 2002
    ..evidence, as well as assurances from international health advisory groups, that mercury release from dental amalgam poses no health threat to the general population (Mackert and Berglund, 1997a, b), a number of countries have ..
  14. IMMUNOTOXIC PROPERTIES OF MERCURIC COMPOUNDS
    BRUCE SHENKER; Fiscal Year: 2003
    ..Sources of human exposure to mercury include seafood, seeds, foodstuffs, water, and dental amalgam. In previous studies, the Principal Investigator has shown that mercury, at low concentrations, kills human ..