Genomes and Genes
Summary: Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.
Publications309 found, 100 shown here
- Percutaneous vertebroplastyDavid F Kallmes
Department of Radiology, University of Virginia Health Sciences Center, PO Box 800170, Charlottesville, VA 22908, USA
Radiology 229:27-36. 2003..Finally, the current state of evidence in support of the efficacy of vertebroplasty are discussed, with particular attention to the need for ongoing clinical trials...
- Bone substitutes: an updatePeter V Giannoudis
Academic Department of Orthopaedics and Trauma, St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
Injury 36:S20-7. 2005..We present here an overview of bone grafts and graft substitutes available for clinical applications...
- The Norwegian Arthroplasty Register: 11 years and 73,000 arthroplastiesL I Havelin
Department of Orthopaedic Surgery, Haukeland University Hospital, Norway
Acta Orthop Scand 71:337-53. 2000..Since the practice of using undocumented implants has not changed, the register will continue to survey these implants. We plan to assess the mid- and long-term results of implants that have so far had good short-term results...
- Cemented versus uncemented hemiarthroplasty for displaced femoral neck fracturesWender Figved
Orthopaedic Centre, Ulleval University Hospital, Oslo, Norway
Clin Orthop Relat Res 467:2426-35. 2009..The rates of complications and mortality were similar between groups. Both arthroplasties may be used with good results after displaced femoral neck fractures...
- New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fracturesS R Garfin
University of California, San Diego, California, USA
Spine (Phila Pa 1976) 26:1511-5. 2001..Literature review...
- Percutaneous vertebroplasty for spinal metastases: complicationsHéctor Manuel Barragán-Campos
Department of Diagnostic and Interventional Neuroradiology, Groupe Hospitalier Pitie Salpetriere, Universite Pierre et Marie Curie Paris VI, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
Radiology 238:354-62. 2006..To retrospectively evaluate complications of percutaneous vertebroplasty (PV) performed with polymethylmethacrylate cement to treat pain in patients with metastases to the spine...
- Percutaneous transpedicular vertebroplasty with calcium phosphate cement in the treatment of osteoporotic vertebral compression and burst fracturesMasato Nakano
Department of Orthopaedic Surgery, Toyama Rosai Hospital, Japan
J Neurosurg 97:287-93. 2002..The authors describe a series of patients in whom they performed percutaneous vertebroplasty by using calcium phosphate cement (CPC) to obtain early pain relief and improve the integrity of the osteoporotic vertebral body (VB)...
- Hemiarthroplasty of the hip with and without cement: a randomized clinical trialFraser Taylor
Auckland City Hospital, Private Bag 92 024, Auckland Mail Centre, Auckland 1142, New Zealand
J Bone Joint Surg Am 94:577-83. 2012..The primary hypothesis of this study was that use of cement would provide better visual analog pain scores following this procedure in an elderly patient population...
- Development of a strontium-containing hydroxyapatite bone cementDagang Guo
State Key Laboratory for Mechanical Behavior of Materials, Xi an Jiaotong University, Xianning Western Road No 28, Xi an, Shaan X 710049, China
Biomaterials 26:4073-83. 2005....
- Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trialDouglas Wardlaw
Orthopaedic Department, Woodend Hospital, NHS Grampian, Aberdeen, UK
Lancet 373:1016-24. 2009..Balloon kyphoplasty is a minimally invasive procedure for the treatment of painful vertebral fractures, which is intended to reduce pain and improve quality of life. We assessed the efficacy and safety of the procedure...
- Giant cell tumor of bone: risk factors for recurrenceFrank M Klenke
Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Clin Orthop Relat Res 469:591-9. 2011..However, the best treatment of these tumors and risk factors for recurrence remain controversial...
- Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trialCaroline A H Klazen
Radiology, St Elisabeth Ziekenhuis, Tilburg, Netherlands
Lancet 376:1085-92. 2010..We aimed to clarify whether vertebroplasty has additional value compared with optimum pain treatment in patients with acute vertebral fractures...
- An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplastyFrank M Phillips
University of Chicago Spine Center, Chicago, Illinois 60640, USA
Spine (Phila Pa 1976) 27:2173-8; discussion 2178-9. 2002..A prospective in vivo study was conducted during the performance of kyphoplasty for the treatment of osteoporotic vertebral compression fractures, comparing extravertebral contrast extravasation with kyphoplasty and vertebroplasty...
- Bioactive bone cement as a principal fixture for spinal burst fracture: an in vitro biomechanical and morphologic studyW W Lu
Department of Orthopaedic Surgery, University of Hong Kong, China
Spine (Phila Pa 1976) 26:2684-90; discussion 2690-1. 2001..An in vitro biomechanical and radiographic study to evaluate the properties of a newly developed bioactive bone cement for stabilization of the fractured spine, suitable for minimally invasive application...
- A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastasesIra J Miller
Department of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison 300 Chicago, IL, 60612, USA
Diagn Pathol 5:62. 2010..Here we report a case of GCT of bone that at the time of recurrence was found to have undergone malignant transformation. Concurrent metastases were found in the lung, but these were non-transformed GCT...
- Durable infection control and function with the PROSTALAC spacer in two-stage revision for infected knee arthroplastyChristopher R Gooding
Division of Lower Limb Reconstruction and Oncology, Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada
Clin Orthop Relat Res 469:985-93. 2011..The PROSTALAC knee spacer is an antibiotic-loaded cement articulating spacer that allows some movement of the knee between stages. Whether motion enhances long-term function is unknown...
- Adjacent vertebral fractures after percutaneous vertebral augmentation of osteoporotic vertebral compression fracture: a comparison of balloon kyphoplasty and vertebroplastyI Movrin
Department of Traumatology, University Medical Centre Maribor, Ljubljanska 5, Maribor, Slovenia
Arch Orthop Trauma Surg 130:1157-66. 2010..The purpose of this study was to evaluate the adjacent level fracture risk after BK as compared with VP and to determine the possible dominant risk factor associated with new compression fractures...
- An intraoperatively moulded PMMA prostheses like spacer for two-stage revision of infected total knee arthroplastySandro Kohl
Department of Orthopaedic Surgery, Inselspital, University of Bern, Switzerland
Knee 18:464-9. 2011..The use of this spacer is a time sparing, cheap and convenient option in 2-stage TKA revision...
- Shrinkage stresses in bone cementJ F Orr
School of Mechanical and Manufacturing Engineering, Queen s University Belfast, Ashby Building, Stranmillis Road, Belfast BT9 5AH, UK
Biomaterials 24:2933-40. 2003..Moduli of elasticity values were measured for acrylic bone cements ranging from 2.1 to 2.7GPa, as were Poisson's ratio values ranging from 0.38 to 0.46...
- Early radiographic and clinical results of balloon kyphoplasty for the treatment of osteoporotic vertebral compression fracturesFrank M Phillips
The University of Chicago Spine Center, Chicago, Illinois, USA
Spine (Phila Pa 1976) 28:2260-5; discussion 2265-7. 2003..A prospective consecutive cohort study of clinical and radiographic outcomes after kyphoplasty for treatment of osteoporotic vertebral compression fractures...
- Development of specimen-specific finite element models of human vertebrae for the analysis of vertebroplastyV N Wijayathunga
School of Mechanical Engineering, University of Leeds, Leeds, UK
Proc Inst Mech Eng H 222:221-8. 2008....
- In vitro activities of daptomycin-, vancomycin-, and teicoplanin-loaded polymethylmethacrylate against methicillin-susceptible, methicillin-resistant, and vancomycin-intermediate strains of Staphylococcus aureusYuhan Chang
Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Antimicrob Agents Chemother 55:5480-4. 2011The objective of this study was to evaluate the antibacterial effects of polymethylmethacrylate (PMMA) bone cements loaded with daptomycin, vancomycin, and teicoplanin against methicillin-susceptible Staphylococcus aureus (MSSA), ..
- Biomechanical study of pedicle screw fixation in severely osteoporotic boneStephen D Cook
Tulane University Health Sciences Center, Department of Orthopaedic Surgery, 1430 Tulane Avenue, SL 32, New Orleans, LA 70112, USA
Spine J 4:402-8. 2004..An expandable pedicle screw design has been shown to significantly improve fixation compared to a conventional screw in poor quality bone...
- Bone cement implantation syndromeA J Donaldson
Department of Anaesthesia, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK
Br J Anaesth 102:12-22. 2009..Invasive anaesthetic monitoring should be considered during cemented arthroplasty in high risk patients...
- Two-stage total hip arthroplasty: how often does it control methicillin-resistant infection?Fay Leung
Department of Orthopaedics, University of British Columbia, 3114 910 West 10th Avenue, Vancouver, BC V5Z 4E3, Canada
Clin Orthop Relat Res 469:1009-15. 2011..Methicillin-resistant hip infections are increasingly common. Reports of the surgical management of these patients using two-stage THA show variable control of infection, but all reports used static spacers...
- Mixed-mode failure strength of implant-cement interface specimens with varying surface roughnessJ Zelle
Orthopaedic Research Laboratory, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
J Biomech 44:780-3. 2011..The findings presented in this paper can be used in numerical models to simulate loosening at the implant-cement interface...
- Mechanical and histological evaluation of a PMMA-based bone cement modified with gamma-methacryloxypropyltrimethoxysilane and calcium acetateTadashi Tsukeoka
Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8677, Japan
Biomaterials 27:3897-903. 2006..The modification was found to be effective in enabling osteoconduction with PMMA bone cement, thus providing stable fixation for a long period after implantation...
- Cemented versus uncemented hemiarthroplasty for displaced femoral neck fractures: a prospective randomized trial with early follow-upJoseph P Deangelis
Department of Orthopaedics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
J Orthop Trauma 26:135-40. 2012..To prospectively compare the functional outcome associated with cemented and uncemented hemiarthroplasty...
- Bone substitutes in vertebroplastyP F Heini
Department of Orthopaedic Surgery, Spine Service, Inselspital, University of Bern, Switzerland
Eur Spine J 10:S205-13. 2001..Animal studies confirm their biocompatibility and osteoconductivity. However, handling problems and the limited radiopacity of these cements currently preclude their clinical use...
- The Harris-Galante porous-coated, hemispherical, polyethylene-lined acetabular component in patients under 50 years of age: a 12- to 16-year reviewM R Utting
Royal Perth Rehabilitation Hospital, 6 Selby Street, Shenton Park, Western Australia 6008, Australia
J Bone Joint Surg Br 90:1422-7. 2008..5 to 93.5) and for impending revision 55.3% (95% confidence interval 40.6 to 70) at 16 years. Uncemented acetabular components with polyethylene liners undergo silent lysis and merit regular long-term radiological review...
- Primary pedicle screw augmentation in osteoporotic lumbar vertebrae: biomechanical analysis of pedicle fixation strengthDaniel J Burval
Cleveland Clinic Foundation, Cleveland Clinic Spine Institute, Cleveland, OH 44195, USA
Spine (Phila Pa 1976) 32:1077-83. 2007..Pedicle screw pullout testing in osteoporotic and control human cadaveric vertebrae, comparing augmented and control vertebrae...
- Injectable PLGA microsphere/calcium phosphate cements: physical properties and degradation characteristicsW J E M Habraken
Department of Periodontology and Biomaterials, College of Dental Science, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
J Biomater Sci Polym Ed 17:1057-74. 2006..In conclusion, all physical parameters were well within workable ranges with both 10:90 and 20:80 PLGA microsphere/CaP cements. After 12 weeks the PLGA was totally degraded and a highly porous, but strong scaffold remained...
- 18 years of results with cemented primary hip prostheses in the Norwegian Arthroplasty Register: concerns about some newer implantsBirgitte Espehaug
The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
Acta Orthop 80:402-12. 2009..We studied long-term outcome based on data in the Norwegian Arthroplasty Register...
- Pullout strength of pedicle screws augmented with particulate calcium phosphate: an experimental studyAta Hashemi
Department of Mechanical Engineering, McMaster University, 1280 Main Street, Hamilton, ON L8L 568, Canada
Spine J 9:404-10. 2009Pressure-injected and in situ curing bone cements have been studied as alternatives in augmenting lumbar pedicle screw fixation but are frequently found to leak outside the confines of the target vertebra.
- Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivoKonstantinos Anagnostakos
Klinik fur Orthopadie und Orthopadische Chirurgie, Universitat des Saarlandes, Homburg Saar, Germany
Acta Orthop 80:193-7. 2009..However, little is known about antibiotic elution from bone cement beyond the first 2-3 postoperative days in humans...
- New fractures after vertebroplasty: adjacent fractures occur significantly soonerA T Trout
Mayo Clinic College of Medicine, Rochester, MN 55905, USA
AJNR Am J Neuroradiol 27:217-23. 2006..We specifically hypothesized that subsequent fractures would occur sooner and more frequently in the vertebrae adjacent to the treated level...
- Biomechanical evaluation of vertebroplasty and kyphoplasty with polymethyl methacrylate or calcium phosphate cement under cyclic loadingHans Joachim Wilke
Institute of Orthopaedic Research and Biomechanics, University of Ulm, Ulm, Germany
Spine (Phila Pa 1976) 31:2934-41. 2006..We developed a new method to simulating in vivo dynamic loading as closely as possible, which allows comparison of kyphoplasty and vertebroplasty, as well as augmentation materials...
- Cemented tibial component fixation performs better than cementless fixation: a randomized radiostereometric study comparing porous-coated, hydroxyapatite-coated and cemented tibial components over 5 yearsAke Carlsson
Department of Orthopedicsy, Malmo University Hospital, SE 205 02 Malmo, Sweden
Acta Orthop 76:362-9. 2005....
- Percutaneous vertebroplasty: history, technique and current perspectivesI G Hide
Department of Radiology, Freeman Hospital, Newcastle upon Tyne, UK
Clin Radiol 59:461-7. 2004..NICE guidelines are now available for this procedure, which is relatively new in the UK, but has been performed for more than 15 years in continental Europe...
- Biomechanical comparison of kyphoplasty with different bone cementsSeiji Tomita
Orthopaedic Instrumentation Laboratory, Department of Orthopaedic Surgery, Johns Hopkins University Johns Hopkins Bay view Medical Center, Baltimore, MD 21224 2780, USA
Spine (Phila Pa 1976) 29:1203-7. 2004..Ex vivo biomechanical study...
- Comparison of total hip arthroplasty performed with and without cement : a randomized trialAndreas Laupacis
Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Bone Joint Surg Am 84:1823-8. 2002..This study was designed to compare the fixation of a Mallory-Head total hip prosthesis with and without cement...
- Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticlesZhilong Shi
Department of Chemical and Biomolecular Engineering, National University of Singapore, 10 Kent Ridge, Singapore 119260, Singapore
Biomaterials 27:2440-9. 2006..The inhibition of S. aureus and S. epidermidis growth on the surface of the CS NP and QCS NP-loaded bone cements was clearly shown using the LIVE/DEAD Baclight bacterial viability kits and fluorescence microscopy...
- Effect of postoperative mechanical axis alignment on the fifteen-year survival of modern, cemented total knee replacementsSebastien Parratte
Department of Orthopedic Surgery, Mayo Clinic, 200 First Street S W, Rochester, MN 55905, USA
J Bone Joint Surg Am 92:2143-9. 2010..We hypothesized that a postoperative mechanical axis of 0° ± 3° would result in better long-term survival of total knee arthroplasty implants as compared with that in a group of outliers...
- Antibiotic-loaded bone cement spacers in two-stage management of infected total knee arthroplastyR P Pitto
Department of Orthopaedic Surgery, South Auckland Clinical School, University of Auckland, Auckland, New Zealand
Int Orthop 28:129-33. 2004..Last but not the least, the cost of spacers represents only a small fraction of the total expenses for management of infected knee arthroplasties...
- Infection of orthopedic implants and the use of antibiotic-loaded bone cements. A reviewH van de Belt
Department of Orthopedic Surgery, University Hospital Groningen, The Netherlands
Acta Orthop Scand 72:557-71. 2001..made to prevent and cure orthopedic implant infections by incorporating antibiotics in polymethylmethacrylate bone cements, in primary and revision surgery...
- Is there a difference in perioperative mortality between cemented and uncemented implants in hip fracture surgery?M Hossain
Department of Trauma and Orthopaedics, Ysbyty Gwynedd Hospital, Penrhosgarnedd Road, Bangor LL57 2LW, Wales, UK
Injury 43:2161-4. 2012..We compared the incidence and pattern of 48 h perioperative mortality between patients receiving cemented and uncemented implants after hip fracture surgery...
- Temperature elevation after vertebroplasty with polymethyl-methacrylate in the goat spineJorrit Jan Verlaan
Department of Orthopaedics, University Medical Center Utrecht, The Netherlands
J Biomed Mater Res B Appl Biomater 67:581-5. 2003..0 and 37.5 degrees C, respectively. The local temperature measured after in vivo vertebroplasty did not reach values that are known to cause tissue necrosis...
- Antimicrobial activity of gentamicin palmitate against high concentrations of Staphylococcus aureusClemens Kittinger
Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria
J Mater Sci Mater Med 22:1447-53. 2011..Both pre and post operative systemic antibiotic treatment and gentamicin containing bone cements (polymethylmethacrylate, PMMA) are commonly used strategies to overcome infections...
- Characterization of daptomycin-loaded antibiotic cementLige Kaplan
Department of Orthopaedic Surgery, Beaumont Health System, Royal Oak, Michigan 48073, USA
Orthopedics 35:e503-9. 2012..Based on the findings of our study, 2 g of daptomycin and 3.6 g of tobramycin per 40-g packet of cement should be used to promote daptomycin elution without sacrificing PMMA mechanical properties...
- Antibiotic-loaded bone cement reduces deep infection rates for primary reverse total shoulder arthroplasty: a retrospective, cohort study of 501 shouldersRobert J Nowinski
Orthopaedic and Neurological Consultants, Inc, New Albany, OH 43054, USA
J Shoulder Elbow Surg 21:324-8. 2012..We conducted a retrospective cohort study to evaluate the effect of antibiotic-loaded bone cement vs plain bone cement on the prevention of deep infection after primary reverse total shoulder arthroplasty...
- Evaluation of the ultrasonication process for injectability of hydraulic calcium phosphate pastesMohamed Habib
Laboratoire de Biomecanique, Département de Génie, Universite de Sherbrooke, Sherbrooke, Quebec, Canada J1K 2R1
Acta Biomater 8:1164-8. 2012..4 ± 2.3% without ultrasonication to 97.3 ± 2.4% with 30%. This result shows that ultrasonication is an effective solution to improve injectability...
- Biocompatibility and osteogenicity of degradable Ca-deficient hydroxyapatite scaffolds from calcium phosphate cement for bone tissue engineeringHan Guo
Key Laboratory for Ultrafine Materials of Ministry of Education, and Engineering Research Center for Biomedical Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, PR China
Acta Biomater 5:268-78. 2009..However, the CDHA scaffolds showed as good biocompatibility and osteogenicity as the hybrid ones at 8 weeks. These results indicate that the CDHA scaffolds fulfill the basic requirements of bone tissue engineering scaffold...
- Self-setting bioactive calcium-magnesium phosphate cement with high strength and degradability for bone regenerationFan Wu
Key Laboratory for Ultrafine Materials of Ministry of Education, Engineering Research Center for Biomedical Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, People s Republic of China
Acta Biomater 4:1873-84. 2008....
- A randomized trial of vertebroplasty for osteoporotic spinal fracturesDavid F Kallmes
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
N Engl J Med 361:569-79. 2009..Vertebroplasty is commonly used to treat painful, osteoporotic vertebral compression fractures...
- Porous surface modified bioactive bone cement for enhanced bone bondingQiang He
Institute of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, People s Republic of China
PLoS ONE 7:e42525. 2012..Bioactive bone cements show bone bonding ability, but their clinical application is limited because bone resorption is observed after ..
- Cardiac perforation and tricuspid regurgitation as a complication of percutaneous vertebroplastyKuk Hui Son
Department of Thoracic and Cardiovascular Surgery, Korea University Medical Center, Seoul, Republic of Korea
Eur J Cardiothorac Surg 33:508-9. 2008....
- Micro and nano MgO particles for the improvement of fracture toughness of bone-cement interfacesMORSHED KHANDAKER
Department of Engineering and Physics, University of Central Oklahoma, Edmond, OK 73034, USA
J Biomech 46:1035-9. 2013..0001). Results indicated that the addition of the micro and nano MgO particles to PMMA improved the quality of bone-cement union...
- Anterior spinal column augmentation with injectable bone cementsJorrit Jan Verlaan
Department of Orthopaedics, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
Biomaterials 27:290-301. 2006..In this paper, both vertebroplasty and balloon vertebroplasty and their respective indications, techniques and results are described in relation with the application and limitations of permanent and resorbable injectable bone cements.
- Asymptomatic diffuse pulmonary embolism caused by acrylic cement: an unusual complication of percutaneous vertebroplastyJ Bernhard
Department of Rheumatology and Clinical Immunology Allergology, University Hospital, CH 3010 Berne, Switzerland
Ann Rheum Dis 62:85-6. 2003
- The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodiesMarta L Villarraga
Exponent, Inc, 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA
J Spinal Disord Tech 18:84-91. 2005..Therefore, subsequent adjacent level fractures may be related to the underlying etiology (weakening of the bone) rather than the surgical intervention...
- Bone cement with reduced proportion of monomer in total hip arthroplasty: preclinical evaluation and randomized study of 47 cases with 5 years' follow-upB Nivbrant
Department of Orthopedics, NUS, University Hospital of Northern Sweden, Umea
Acta Orthop Scand 72:572-84. 2001..Collagen markers (PICP, ICTP) showed similar increases in bone turnover 6 weeks and 6 months after operation in both groups...
- Prophylaxis and treatment of implant-related infections by local application of antibioticsMichael Diefenbeck
Klinik fur Unfall und Wiederherstellungschirurgie, Berufsgenossenschaftliche Kliniken Bergmannstrost, Halle Saale, Germany
Injury 37:S95-104. 2006..The second part discusses the role of local antibiotics such as gentamicin PMMA beads, and gentamicin-collagen and antibiotic-loaded cement spacers in treating implant-related infections...
- Aseptic loosening, not only a question of wear: a review of different theoriesMikael Sundfeldt
Department of Biomaterials Handicap Research, Sahlgrenska University Hospital, University of Gothenburg, Sweden
Acta Orthop 77:177-97. 2006..In this review, we discuss the most common theories concerning aseptic loosening. It emerges from this review that aseptic loosening has a multifactorial etiology and cannot be explained by a single theory...
- Quality assurance guidelines for percutaneous vertebroplastyAfshin Gangi
Department of Radiology, University Louis Pasteur, Strasbourg, France
Cardiovasc Intervent Radiol 29:173-8. 2006
- Balloon kyphoplasty and vertebroplasty for vertebral compression fractures: a comparative systematic review of efficacy and safetyRod S Taylor
Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, United Kingdom
Spine (Phila Pa 1976) 31:2747-55. 2006..Systematic review and meta-regression...
- Renal cement embolism during percutaneous vertebroplastySeung Eun Chung
Department of Diagnostic Radiology, Wooridul Spine Hospital, Seoul, Republic of Korea
Eur Spine J 15:590-4. 2006..leakage occurred outside of the anterior cortical fracture site of the L1 vertebral body, and multiple tubular bone cements migrated to the course of the renal vessels via the valveless collateral venous network surrounding the L1 body...
- Physico-chemical-mechanical and in vitro biological properties of calcium phosphate cements with doped amorphous calcium phosphatesMarion Julien
INSERM, U 791, 1 place A Ricordeau, Nantes, F 44042, France
Biomaterials 28:956-65. 2007..The total porosity of Mg-CPC was greater compared to Zn-CPC or F-CPC. Osteoblast-like cells, MC3T3-E1, remained viable and maintained their ability to express alkaline phosphatase in contact with the CPCs with doped ACCPs...
- Intraoperative molds to create an articulating spacer for the infected knee arthroplastyGeoffrey S Van Thiel
Rush University Medical Center, 1611 West Harrison Street, Suite 300, Chicago, IL 60612, USA
Clin Orthop Relat Res 469:994-1001. 2011....
- In vitro elution of vancomycin from calcium phosphate cementTomoyuki Sasaki
Department of Orthopaedic Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
J Arthroplasty 20:1055-9. 2005..From this study, we concluded that VCM-impregnated CPC might be an effective material for the treatment of osteomyelitis and/or prosthesis infection...
- Articulating spacers used in two-stage revision of infected hip and knee prostheses abrade with timeBernd Fink
Clinic of Joint Replacement, General and Rheumatic Orthopaedics, Orthopaedic Clinic Markgröningen gGmbH, Kurt Lindemann Weg 10, 71706 Markgröningen, Germany
Clin Orthop Relat Res 469:1095-102. 2011..Articulating spacers used in two-stage revision surgery of infected prostheses have the potential to abrade and subsequently induce third-body wear of the new prosthesis...
- Vertebroplasty by use of a strontium-containing bioactive bone cementKenneth M C Cheung
Department of Orthopaedics and Traumatology, University of Hong Kong, Hong Kong, China
Spine (Phila Pa 1976) 30:S84-91. 2005..A review of the laboratory and clinical data for a new strontium-containing hydroxyapatite bioactive bone cement...
- Bone response and mechanical strength of rabbit femoral defects filled with injectable CaP cements containing TGF-beta 1 loaded gelatin microparticlesDennis P Link
Department of Periodontology and Biomaterials, Radboud University Nijmegen Medical Center, Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Biomaterials 29:675-82. 2008..The results of this study showed that CaP/gelatin composites show excellent osteogenic properties and a rapid increase in mechanical strength. The addition of TGF-beta1 significantly enhances the bone remodeling process...
- The operation of the century: total hip replacementIan D Learmonth
Department of Orthopaedics, Bristol Royal Infirmary, Bristol BS2 8HW, UK
Lancet 370:1508-19. 2007..Universal economic constraints in healthcare services dictate that further developments in total hip replacement will be governed by their cost-effectiveness...
- Percutaneous vertebroplasty for the treatment of burst fractures. Case reportJyi Feng Chen
Department of Neurosurgery, Chang Gung University and Chang Gung Memorial Hospital, Taoyuan, Taiwan, Republic of China
J Neurosurg Spine 1:228-31. 2004..The authors propose this procedure as a useful intervention in selected patients with lumbar burst fractures. The complications associated with major surgical procedures are absent...
- Bioactive cement or ceramic/porous coating vs. conventional cement to obtain early stability of the acetabular cup. Randomised study of 96 hips followed with radiostereometryGeorgios Digas
Department of Orthopaedics, Sahlgrenska University Hospital, S 41345 Goteborg, Sweden
J Orthop Res 22:1035-43. 2004..Uncemented cups had less radiolucent lines at 2 years. Fluoride containing cement or uncemented fixation did not improve the early postoperative stability of the socket...
- Total hip arthroplasty for primary osteoarthrosis in younger patients in the Finnish arthroplasty register. 4,661 primary replacements followed for 0-22 yearsAntti Eskelinen
Department of Orthopedics, Surgical Hospital, Helsinki University Central Hospital, Helsinki, Finland
Acta Orthop 76:28-41. 2005..Many studies have found a higher risk of revision after hip arthroplasty in younger patients. We evaluated the population-based survival of total hip arthroplasty (THA) in patients under 55 years of age and the factors affecting survival...
- High rate of aminoglycoside resistance among staphylococci causing prosthetic joint infectionPaloma Anguita-Alonso
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Clin Orthop Relat Res 439:43-7. 2005..The findings suggest that consideration should be given to the further study of agents other than aminoglycosides for incorporation into polymethylmethacrylate for the treatment and prevention of prosthetic joint infection...
- Finite element and experimental models of cemented hip joint reconstructions can produce similar bone and cement strains in pre-clinical testsJ Stolk
Orthopaedic Research Laboratory, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, Netherlands
J Biomech 35:499-510. 2002..The objective of overall agreement within 10% was achieved, indicating that both FE models were successfully validated. This prerequisite for accurately predicting long-term failure has been satisfied...
- Calcium-phosphate-silicate composite bone cement: self-setting properties and in vitro bioactivityZhiguang Huan
Biomaterials and Tissue Engineering Research Center, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai, 200050, People s Republic of China
J Mater Sci Mater Med 20:833-41. 2009..With good hydraulic properties, improved biocompatibility and moderate degradability, the novel DCPD/C(3)S bone cement may be a potential candidate as bone substitute...
- Cement augmentation of intertrochanteric fractures stabilised with intramedullary nailingC Dall'Oca
Department of Orthopaedic and Traumatology, University of Verona, G B Rossi Hospital, Piazzale Scuro 10, 37134 Verona, Italy
Injury 41:1150-5. 2010..We believe that in femoral intertrochanteric fractures cement augmentation could improve the mechanical stability of the implant, ensuring early functional recovery...
- Alginate/poly (lactic-co-glycolic acid)/calcium phosphate cement scaffold with oriented pore structure for bone tissue engineeringXiaopeng Qi
Key Laboratory of Specially Functional Materials, Ministry of Education, South China University of Technology, Guangzhou 510641, China
J Biomed Mater Res A 89:980-7. 2009..Alginate/PLGA/CPC scaffold preserved the open directional macropores and might be a potential scaffold for bone tissue engineering...
- Multi-axial loading micromechanics of the cement-bone interface in postmortem retrievals and lab-prepared specimensMark A Miller
SUNY Upstate Medical University, Syracuse, NY, USA
J Mech Behav Biomed Mater 4:366-74. 2011..The magnitude of the compliance could be modified to simulate immediate post-operative conditions (using laboratory prepared data set) or long-term remodeling (using postmortem data set)...
- Vertebroplasty and kyphoplasty: reasons for concern?Luca Denaro
Department of Neurosurgery, Catholic University School of Medicine, Policlinico Gemelli, Largo Gemelli 8, 00168 Rome, Italy
Orthop Clin North Am 40:465-71, viii. 2009..This article provides an overview of the state of the art in vertebroplasty and kyphoplasty, discussing the indications, techniques, results, and pitfalls...
- A randomized trial of vertebroplasty for painful osteoporotic vertebral fracturesRachelle Buchbinder
Monash Department of Clinical Epidemiology, Cabrini Hospital, and Monash University, Malvern, Vic, Australia
N Engl J Med 361:557-68. 2009..Vertebroplasty has become a common treatment for painful osteoporotic vertebral fractures, but there is limited evidence to support its use...
- Vesselplasty: a new technical approach to treat symptomatic vertebral compression fracturesLucía Flors
Department of Radiology, Hospital Universitario Doctor Peset, Avd Gaspar Aguilar 90, Valencia 46017, Spain
AJR Am J Roentgenol 193:218-26. 2009..The objective of our study was to evaluate the effectiveness and safety of vesselplasty to treat symptomatic vertebral compression fractures (VCFs)...
- The long-term results of the original Exeter polished cemented femoral component: a follow-up reportRobin S M Ling
Princess Elizabeth Orthopaedic Centre Exeter, United Kingdom
J Arthroplasty 24:511-7. 2009..With the end point reoperation for aseptic stem loosening, the survivorship is 93.5% (95% confidence interval, 90.0%-97.0%). The reoperation rate for aseptic femoral component loosening is 3.23% into the 33rd year of follow-up...
- The cytocompatibility and early osteogenic characteristics of an injectable calcium phosphate cementDennis P Link
Radboud University Nijmegen Medical Center, Department of Periodontology and Biomaterials, Nijmegen, The Netherlands
Tissue Eng 13:493-500. 2007..In contrast to in vivo studies, the Calcibon CaP cement is not suitable as a scaffold for cell-based tissue-engineering strategies...
- Metal-backed acetabular components with conventional polyethylene: a review of 9113 primary components with a follow-up of 20 yearsG Hallan
Department of Orthopaedic Surgery, Haukeland University Hospital, Jonas Liesvei 65, 5021 Bergen, Norway geir hallan helse bergen no
J Bone Joint Surg Br 92:196-201. 2010..None of the metal-backed uncemented acetabular components with ultra-high-molecular-weight polyethylene liners in our study had satisfactory long-term results because of high rates of wear, osteolysis, aseptic loosening and dislocation...
- The influence of cement viscosity on the early migration of a tapered polished femoral stemS Glyn-Jones
Oxford Orthopaedic Engineering Centre, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7LD, UK
Int Orthop 27:362-5. 2003..For a polished, tapered implant that is designed to subside, cement viscosity does not influence the 1-year migration, and it is therefore unlikely to affect long-term outcome...
- Evaluation of calcium sulfate paste for augmentation of lumbar pedicle screw pullout strengthMichael T Rohmiller
Vanderbilt University, Department of Orthopedics and Rehabilitation, Vanderbilt University Spine Center, Nashville, TN, USA
Spine J 2:255-60. 2002..Calcium sulfate is an alternative to PMMA, because it lacks the exothermic reaction, is potentially osteoconductive and is resorbed by the body in 30 to 60 days...
- Addressing severe bone deficiency: what a cage will not doWayne G Paprosky
Department of Orthopaedic Surgery, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois
J Arthroplasty 22:111-5. 2007..Deficiencies of acetabular bone can be independently addressed and reconstructed providing initial stability and, we believe, long-term biologic fixation to host bone...
- Augmentation of pedicle screw fixation strength using an injectable calcium sulfate cement: an in vivo studyXiaodong Yi
Department of Orthopedic Surgery, Peking University First Hospital, Beijing, China
Spine (Phila Pa 1976) 33:2503-9. 2008..An in vivo landrace model of cement augmentation of pedicle screw was established, and axial pull-out tests and histological analysis were performed...
- The rates of osteolysis and loosening associated with a modular posterior stabilized knee replacement. Results at five to fourteen yearsPaul F Lachiewicz
Department of Orthopaedics, University of North Carolina, Chapel Hill, 242 Burnett Womack Building, CB 7055, Chapel Hill, NC 27599, USA
J Bone Joint Surg Am 86:525-30. 2004..The purpose of the present study was to evaluate a modular posterior stabilized prosthesis to determine its clinical performance as well as the rates of component loosening and osteolysis...
- Assessment of different screw augmentation techniques and screw designs in osteoporotic spinesS Becker
Spine Centre, Orthopaedic Hospital Speising, Vienna, Austria
Eur Spine J 17:1462-9. 2008..Nevertheless, using a properly designed perforated screw will facilitate augmentation and instrumentation in osteoporotic spines...
- Local recurrence of giant cell tumor of bone after intralesional treatment with and without adjuvant therapyWolfgang T Becker
Orthopädische Klinik Volmarstein, Universitat Witten Herdecke, Wetter, Germany
J Bone Joint Surg Am 90:1060-7. 2008..The purpose of this study was to analyze the rates of recurrence following different types of treatment as well as the influence of various factors of tumor presentation on those rates...
- Giant-cell tumor of the distal forearmNeil G Harness
Orthopaedic Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Hand Surg Am 29:188-93. 2004..We have studied the results from our institution for 49 patients with giant-cell tumors of the distal forearm treated from 2 to 28 years (mean, 14 +/- 7 years) and compared the results for different methods of treatment...
- Micro-mechanical modeling of the cement-bone interface: the effect of friction, morphology and material properties on the micromechanical responseDennis Janssen
Radboud University Nijmegen Medical Centre, Orthopaedic Research Laboratory, P O Box 9101, 6500 HB Nijmegen, The Netherlands
J Biomech 41:3158-63. 2008..The current study provides information that may help to better understand the load-transfer mechanisms taking place at the cement-bone interface...
- Clinical effectiveness of antibiotic-impregnated cement spacers for the treatment of infected implants of the hip jointKengo Yamamoto
Department of Orthopedic Surgery, Tokyo Medical University, 6 7 1 Nishi shinjuku, Shinjuku ku, Tokyo 160 0023, Japan
J Orthop Sci 8:823-8. 2003..All revision surgeries were performed using a two-stage procedure. No infection has recurred at a mean follow-up of 3 years 2 months...
- Documentation of hip prostheses used in Norway: a critical review of the literature from 1996--2000Arild Aamodt
Department of Orthopaedic Surgery, Trondheim University Hospital, Trondheim
Acta Orthop Scand 75:663-76. 2004....
- All-polyethylene vs. metal-backed tibial component in total knee arthroplasty-a randomized RSA study comparing early fixation of horizontally and completely cemented tibial components: part 1. Horizontally cemented components: AP better fixated than MBHans Hyldahl
Department of Orthopaedics, St Goran s Hospital, SE 112 81 Stockholm, Sweden
Acta Orthop 76:769-77. 2005..Furthermore, the tibial component can be either horizontally or completely cemented. We evaluated metal backing versus all-polyethylene using horizontal cementing technique...
- Polymethylmethacrylate augmentation of pedicle screw for osteoporotic spinal surgery: a novel techniqueMing Chau Chang
Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Spine (Phila Pa 1976) 33:E317-24. 2008..A retrospective study to evaluate the clinical results of patients with osteoporosis and various spinal diseases treated surgically with polymethylmethacrylate (PMMA) augmented pedicle screw...
- Fatigue Crack Morphology in Cemented HipsAmos Race; Fiscal Year: 2002....
- A Novel Biomimetic Bone Cement For Immediately Loaded Dental ImplantsDAVID ALLEN GAUL; Fiscal Year: 2010..Due to biological and mechanical reasons, the currently available bone cements such as poly(methyl methacrylate) cement and calcium phosphate cement typically used in the cemented orthopedic ..
- DEVELOPMENT OF PICKERING EMULSIONS AS INJECTABLE BONE GRAFTSELIZABETH MARIE COSGRIFF-HERNANDEZ; Fiscal Year: 2013..g., bone cements) or inability to withstand physiological loading (e.g., hydrogels)...
- Polyurethane Bone Cements for Total Hip ImplantsIbrahim Sendijarevic; Fiscal Year: 2010..The technology developed in this study has the potential to improve the lives of over 1.5 million new patients each year who undergo hip replacement surgeries. ..
- Bone cements for delivery of osteoinductive growth factorsJonathan A Hodges; Fiscal Year: 2011DESCRIPTION (provided by applicant): Bone cements are widely used in maxillofacial surgery, repair of cranial defects, and dental fillings...
- Calcium Phosphate Bone Cement NanocompositesKENNETH LAWRENCE LAMBERT; Fiscal Year: 2010..The current prosthesis fixation using PMMA bone cements has a market of about $200 million...
- INJECTABLE RESORBABLE BONE CEMENTJOSEPH GRESSER; Fiscal Year: 1999..characterization of the candidate cements, 5) material loss by cure in aqueous medium, 6) in-vivo screening of bone cements of varying viscosities in rats, 7) in-vivo histological and mechanical evaluation in rabbits, and 8) in-vivo ..
- A NOVEL METAL-POLYMER COMPOSITE FOR AMALGAM REPLACEMENTIvan Stangel; Fiscal Year: 2001..They could be used for indirect restorative procedures in dentistry where metal appliances or single tooth restorations are bonded to enamel/dentin, or as bone cements in orthopedics when metal implants are used.
- BIODEGRADABLE POLYACTIDE-CO-GLYCOLIDE MEDICAL CEMENTSLarry Nichols; Fiscal Year: 2000..As bone cements these new materials can also be expected to lead to products which dispense growth hormones and healing factors ..
- BIOACTIVE CALCIUM PHOSPHATE GLASSES FOR HYPERTHERMIAYONGREN PENG; Fiscal Year: 1993..properties will make such glass ideal as filler to bone defects after curettage of bone tumors, as filler in bone cements, etc. at the same time it is used as thermoseeds...
- Effect of Femoral Stem Design om Cement Mantle FailureAmos Race; Fiscal Year: 2006..Specific Aims: 1 To formulate sub-cement, which will be similar to conventional PMMA bone cements in terms of modulus, yield stress, and viscosity but will be substantially more susceptible to fatigue crack ..
- CERAMIC WHISKER REINFORCEMENT OF DENTAL COMPOSITE RESINSHUAKUN XU; Fiscal Year: 2002....
- Osteolysis and Implant Wear: Biological, Biomedical Engineering, and Surgical PriStuart Goodman; Fiscal Year: 2007..unreadable] [unreadable] [unreadable] [unreadable]..
- Rabbit Model for In Vivo Monitoring of Bone StructureMichael Voor; Fiscal Year: 2003..It will give investigators the opportunity to watch the specific trabecular surfaces that are affected by various treatments and to observe when these effects occur. ..
- P I/II Intraventricular DepoCyt (OD # 06-2348) in Glioblastoma (76,730, 11/06)BRUCE MICHAEL FRANKEL; Fiscal Year: 2010..This has also been the basis for successful application and granting of Orphan-Drug designation for cytarabine (Ara-C) liposome injection (trade name: DepoCyt) for the treatment of gliomas. ..
- Improved Animal Modeling of Saccular AneurysmsDavid F Kallmes; Fiscal Year: 2010..This program will enhance health by preventing the catastrophic events resulting from spontaneous rupture of intracranial aneurysms. ..
- SHAM-CONTROLLED TRIAL OF PERCUTANEOUS VERTEBROPLASTYDavid Kallmes; Fiscal Year: 2008..abstract_text> ..
- Regulation of Cranial Suture Development by TGF-Beta and Fibroblast Growth FactorArun Gosain; Fiscal Year: 2007..This proposal will provide mechanistic insights into the regulation of cranial suture development, and help to relate mouse and human models of craniosynostosis. ..
- Genetic and Tissue Engineering for AneurysmsDavid Kallmes; Fiscal Year: 2004..Successful implementation of this research program will advance the field of genetic and tissue engineering and will improve the care of patients harboring life-threatening cerebral aneurysms. ..
- PREVENTION OF DENTAL CARIESShozo Takagi; Fiscal Year: 2005....
- Infusion of Particles at Implant interfecesStuart Goodman; Fiscal Year: 2006..abstract_text> ..
- Development of a Spinal Intervertebral Disc ProsthesisGLENN BUTTERMANN; Fiscal Year: 2003..The objective of Phase I is to demonstrate that the device restores normal spine biomechanics (range of motion and stiffness) and is durable in fatigue testing. ..
- Fibronectin Antagonists in Cranial Suture FormationAmr Moursi; Fiscal Year: 2006..abstract_text> ..
- Cleveland Clinic Orthopaedic Research Training GrantJOSEPH IANNOTTI; Fiscal Year: 2008..abstract_text> ..
- Outcomes of Furlow&Conventional Palatoplasty ProceduresRobert Havlik; Fiscal Year: 2002..In addition, there have been no studies on the palatal architecture parameters and their influence upon oronasal fistulae and velopharyngeal competence that have been published. ..
- Aging and Fatigue Crack Growth in DentinDWAYNE DALE AROLA; Fiscal Year: 2010..These achievements should reduce the incidence of restorative failures associated with tooth fracture, resulting in billions of dollars in savings of health care costs, as well as a reduction in human suffering. ..
- ENHANCED THERAPY RESPONSE IN OSTEOSARCOMAGENE DIRESTA; Fiscal Year: 2001..The MSKCC Therapeutics faculty believes that the ALS, if successful in this model, has promise as an adjunct for limb salvage procedures and in the treatment of many unresectable or disfiguring tumors. ..
- Fatigue and the Endurance Strength of DentinDwayne Arola; Fiscal Year: 2003..Therefore, results from this study could have tremendous impact on the clinical techniques and procedures used for restorative dentistry. ..