oncogene proteins v fos

Summary

Summary: Transforming proteins coded by fos oncogenes. These proteins have been found in the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses which induce osteogenic sarcomas in mice. The FBJ-MSV v-fos gene encodes a p55-kDa protein and the FBR-MSV v-fos gene encodes a p75-kDa fusion protein.

Top Publications

  1. ncbi Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats
    Judney C Cavalcante
    Laboratory of Chemical Neuroanatomy, Department of Anatomy, Institute of Biomedical Sciences, , , SP-05508-900, Brazil
    Physiol Behav 88:160-6. 2006
  2. ncbi Estrogen and progesterone do not activate Fos in AVPV or LHRH neurons in male rats
    G E Hoffman
    Department of Anatomy and Neurobiology, University of Maryland, School of Medicine, 685 W Baltimore Street, Baltimore, MD 21201, USA
    Brain Res 1054:116-24. 2005
  3. ncbi Habituation reduces novelty-induced FOS expression in the striatum and cingulate cortex
    William M Struthers
    Psychology Department, Wheaton College, 501 East College Ave, Wheaton, IL 60187, USA
    Exp Brain Res 167:136-40. 2005
  4. ncbi Influence of feeding status on neuronal activity in the hypothalamus during lipopolysaccharide-induced anorexia in rats
    L Gautron
    , EA 2972, , 33400 Talence, France
    Neuroscience 134:933-46. 2005
  5. ncbi Effect of acute tyrosine depletion in using a branched chain amino-acid mixture on dopamine neurotransmission in the rat brain
    Marisa Le Masurier
    Department of Pharmacology, Oxford University, UK
    Neuropsychopharmacology 31:310-7. 2006
  6. ncbi Fos responses of dopamine neurons to sociosexual stimuli in male zebra finches
    I S Bharati
    Psychology Department, 9500 Gilman Drive, University of California, San Diego, La Jolla, CA 92093-0109, USA
    Neuroscience 143:661-70. 2006
  7. ncbi Differential fos expression following aspiration, electrolytic, or excitotoxic lesions of the perirhinal cortex in rats
    Melissa J Glenn
    Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Quebec, Canada
    Behav Neurosci 119:806-13. 2005
  8. ncbi A role for midbrain raphe gamma aminobutyric acid neurons in 5-hydroxytryptamine feedback control
    Laura J Boothman
    University Department of Pharmacology, Mansfield Road, Oxford, OX1 3QT, UK
    Neuroreport 16:891-6. 2005
  9. ncbi GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin-induced prolonged noxious stimulation
    Yoshihiro Handa
    Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Pain 117:271-9. 2005
  10. ncbi Enhanced thermal avoidance in mice lacking the ATP receptor P2X3
    Isao Shimizu
    Department of Biological Chemistry, Johns Hopkins School of Medicine, 408 Biophysics Building, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Pain 116:96-108. 2005

Research Grants

  1. Neural Analysis of Maternal Aggression
    STEPHEN GAMMIE; Fiscal Year: 2006
  2. Role of Lateral Septum in Emotional Reactivity During the Postpartum Period
    Stephen C Gammie; Fiscal Year: 2010
  3. Role of Lateral Septum in Emotional Reactivity During the Postpartum Period
    Stephen C Gammie; Fiscal Year: 2011
  4. Nucleus Accumbens-Mediated Feeding: Output Pathways
    Thomas R Stratford; Fiscal Year: 2010
  5. Form/function of Extended Amygdala/Accumbens Shell:CRF
    DANIEL ZAHM; Fiscal Year: 2005
  6. Estrogen Induced Neuroplasticity in the Lordosis Pathway
    LORI FLANAGAN CATO; Fiscal Year: 2004
  7. FUNCTIONAL CORRELATES OF MOLECULAR MARKERS OF ADAPTATION
    Galen Kaufman; Fiscal Year: 2004
  8. Early Experience and Adult Responses to Stress
    Brian Sanders; Fiscal Year: 2003
  9. Optimization of Bimolecular Fluorescence Complementation Probes for New Imaging F
    Tzvi Tzfira; Fiscal Year: 2010
  10. Convergent Versus Parallel Striatal Afferents
    Daniel S Zahm; Fiscal Year: 2010

Detail Information

Publications113 found, 100 shown here

  1. ncbi Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats
    Judney C Cavalcante
    Laboratory of Chemical Neuroanatomy, Department of Anatomy, Institute of Biomedical Sciences, , , SP-05508-900, Brazil
    Physiol Behav 88:160-6. 2006
    ....
  2. ncbi Estrogen and progesterone do not activate Fos in AVPV or LHRH neurons in male rats
    G E Hoffman
    Department of Anatomy and Neurobiology, University of Maryland, School of Medicine, 685 W Baltimore Street, Baltimore, MD 21201, USA
    Brain Res 1054:116-24. 2005
    ..Together, these data indicate that the male lacks a substantial population of steroid receptive AVPV neurons and is unable to respond to the presence of E and P and activate either AVPV or LHRH neurons...
  3. ncbi Habituation reduces novelty-induced FOS expression in the striatum and cingulate cortex
    William M Struthers
    Psychology Department, Wheaton College, 501 East College Ave, Wheaton, IL 60187, USA
    Exp Brain Res 167:136-40. 2005
    ..Behavioral measures of activity decreased with repeated exposure suggesting that the decrease in FLI may be due to either a reduction in motor activity or increasing familiarity with the environments...
  4. ncbi Influence of feeding status on neuronal activity in the hypothalamus during lipopolysaccharide-induced anorexia in rats
    L Gautron
    , EA 2972, , 33400 Talence, France
    Neuroscience 134:933-46. 2005
    ..Together, our data show that fasting modulates lipopolysaccharide-induced anorexia and body weight loss in association with neural changes in specific hypothalamic nuclei...
  5. ncbi Effect of acute tyrosine depletion in using a branched chain amino-acid mixture on dopamine neurotransmission in the rat brain
    Marisa Le Masurier
    Department of Pharmacology, Oxford University, UK
    Neuropsychopharmacology 31:310-7. 2006
    ..This minimal mixture may have use as a dopamine reducing paradigm in patient and volunteer studies...
  6. ncbi Fos responses of dopamine neurons to sociosexual stimuli in male zebra finches
    I S Bharati
    Psychology Department, 9500 Gilman Drive, University of California, San Diego, La Jolla, CA 92093-0109, USA
    Neuroscience 143:661-70. 2006
    ..This colocalization decreased in response to all conspecific stimuli except fighting, and did not decrease following exposure to a heterospecific male...
  7. ncbi Differential fos expression following aspiration, electrolytic, or excitotoxic lesions of the perirhinal cortex in rats
    Melissa J Glenn
    Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Quebec, Canada
    Behav Neurosci 119:806-13. 2005
    ....
  8. ncbi A role for midbrain raphe gamma aminobutyric acid neurons in 5-hydroxytryptamine feedback control
    Laura J Boothman
    University Department of Pharmacology, Mansfield Road, Oxford, OX1 3QT, UK
    Neuroreport 16:891-6. 2005
    ..These findings suggest that activated local GABA neurons may play an important role in 5-HT2 receptor-mediated feedback control of DRN 5-HT neurons...
  9. ncbi GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin-induced prolonged noxious stimulation
    Yoshihiro Handa
    Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Pain 117:271-9. 2005
    ..Moreover, they play an important role in the development of hyperalgesia induced by inflammation...
  10. ncbi Enhanced thermal avoidance in mice lacking the ATP receptor P2X3
    Isao Shimizu
    Department of Biological Chemistry, Johns Hopkins School of Medicine, 408 Biophysics Building, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Pain 116:96-108. 2005
    ..Regardless, this study illustrates the utility of thermal preference assays as part of a comprehensive approach to the analysis of mouse thermosensation...
  11. ncbi Activation of feeding-related neural circuitry after unilateral injections of muscimol into the nucleus accumbens shell
    Thomas R Stratford
    Laboratory of Integrative Neuroscience, University of Illinois at Chicago, 1007 West Harrison Street, Chicago, IL 60607 7137, USA
    Brain Res 1048:241-50. 2005
    ....
  12. ncbi Endogenous opioids and attenuated hypothalamic-pituitary-adrenal axis responses to immune challenge in pregnant rats
    Paula J Brunton
    Laboratory of Neuroendocrinology, Centre for Integrative Physiology, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom
    J Neurosci 25:5117-26. 2005
    ..Thus, the HPA axis responses to immune signals are suppressed in pregnancy at the level of pPVN CRH neurons through an opioid mechanism, possibly acting by preterminal autoinhibition of NTS projections to the pPVN...
  13. ncbi Effect of number of tailshocks on learned helplessness and activation of serotonergic and noradrenergic neurons in the rat
    Luiz F Takase
    Departmento de Anatomia, , , Brasil
    Behav Brain Res 162:299-306. 2005
    ..The relevance of these results for elucidating the neural bases of psychopathology is discussed...
  14. ncbi Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: Evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene
    Anika Agarwal
    Tufts-New England Medical Center, Boston, MA 02111, USA
    Brain Res Mol Brain Res 138:45-57. 2005
    ..Both in vivo and in vitro data point to the importance of PACAP-mediated activation of the cAMP/PKA signaling pathway for stimulation of CRH gene transcription, likely via the CRE...
  15. ncbi Attraction to sexual pheromones and associated odorants in female mice involves activation of the reward system and basolateral amygdala
    Jose Moncho-Bogani
    , , , C. Dr Moliner, 50, 46100 Burjassot, , Spain
    Eur J Neurosci 21:2186-98. 2005
    ..Therefore, the basolateral amygdala stands out as the key centre for vomeronasal-olfactory associative learning...
  16. ncbi Unilateral cortical application of tumor necrosis factor alpha induces asymmetry in Fos- and interleukin-1beta-immunoreactive cells within the corticothalamic projection
    Lynn Churchill
    Department of VCAPP, College of Veterinary Medicine, Washington State University, PO Box 646520, Pullman, WA 99164 6520, USA
    Brain Res 1055:15-24. 2005
    ..Current results indicated that Fos- and IL1beta-IR may be utilized to study the functional neuroanatomy involved in the TNFalpha-mediated state-dependent enhancement of EEG slow wave activity...
  17. ncbi Individual differences in male rat ejaculatory behaviour: searching for models to study ejaculation disorders
    Tommy Pattij
    Department of Anatomy, University Medical Center St Radboud, Nijmegen, The Netherlands
    Eur J Neurosci 22:724-34. 2005
    ..Further exploring the neurobiological mechanisms underlying these differences may be a promising approach to gain insights into the aetiology of sexual dysfunctions such as premature, retarded or an-ejaculation...
  18. ncbi Neural activation during cat odor-induced conditioned fear and 'trial 2' fear in rats
    Lauren G Staples
    School of Psychology, University of Sydney, NSW 2006, Australia
    Neurosci Biobehav Rev 29:1265-77. 2005
    ..Little activation was seen in the amygdala or hippocampus. These results show that stimuli associated with predatory threat come to activate similar brain regions to the threat stimulus itself...
  19. ncbi Maturation of otolith-related brainstem neurons in the detection of vertical linear acceleration in rats
    Suk-King Lai
    Department of Physiology, Faculty of Medicine, The University of Hong Kong, Sassoon Road, Hong Kong
    Eur J Neurosci 23:2431-46. 2006
    ..Taken together, our findings reveal the developmental profile of neuronal subpopulations within the vertical otolith system, thereby providing an anatomical basis for postnatal coding of gravity-related vertical head movements...
  20. ncbi Is neuroplasticity of the hypothalamic-pituitary-adrenal axis maternally mediated?
    Bethany C Reeb
    Department of Psychology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Neurosci 26:5589-90. 2006
  21. ncbi Intrathecal clonidine suppresses zymosan-induced peripheral leukocyte migration in a mouse air pouch model via activation of spinal muscarinic type 2 receptors and sympathoadrenal medullary activity
    Seo-Yeon Yoon
    Department of Veterinary Physiology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, South Korea
    Neuropharmacology 51:829-37. 2006
    ..Collectively, these findings suggest that IT clonidine suppresses peripheral leukocyte migration via a sympathoadrenal medullary pathway, and that this suppressive effect is mediated by spinal M2 receptors...
  22. ncbi Activation of spinally projecting and nitrergic neurons in the PVN following heat exposure
    Joo Lee Cham
    School of Medical Sciences, RMIT University, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 291:R91-101. 2006
    ..1%) (P < 0.0001). These results suggest that spinally projecting and nitrergic neurons in the PVN may contribute to the central pathways activated by thermal stimulation...
  23. ncbi Neuroplasticity of the hypothalamic-pituitary-adrenal axis early in life requires recurrent recruitment of stress-regulating brain regions
    Kristina A Fenoglio
    Department of Anatomy/Neurobiology, University of California, Irvine, California 92697-4475, USA
    J Neurosci 26:2434-42. 2006
    ..These studies provide a neurobiological foundation for the profound neuroplasticity of stress-related genes evoked by early-life experience...
  24. ncbi CNS activational responses to staphylococcal enterotoxin B: T-lymphocyte-dependent immune challenge effects on stress-related circuitry
    Jordi Serrats
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies and The Foundation for Medical Research, La Jolla, California 92037, USA
    J Comp Neurol 495:236-54. 2006
    ..Core SEB-responsive cell groups exclude a medullary-PVH circuit implicated in pituitary-adrenal responses to LPS...
  25. ncbi Activation and circuitry of uterine-cervix-related neurons in the lumbosacral dorsal root ganglia and spinal cord at parturition
    B A Puder
    Department of Neurobiology, Northeastern Ohio Universities College of Medicine, Rootstown, 44272, USA
    J Neurosci Res 82:875-89. 2005
    ..Moreover, some activated sensory neurons may be involved in the animal's perception of labor pain...
  26. ncbi Effect of adrenalectomy on cholecystokinin-8-induced Fos-like immunoreactivity in myenteric neurons and the dorsal vagal complex in rats
    Shannon J Raboin
    Gastroenterology Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine, Tuskegee University, Tuskegee, AL 36088, USA
    Am J Vet Res 67:1552-6. 2006
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Results indicate that the adrenal gland has a role in the activation of myenteric neurons by CCK-8 in rats...
  27. ncbi mGluR2 activation of medial amygdala input impairs vomeronasal organ-mediated behavior
    Christopher M Nolte
    Program in Neuroscience and Department of Biological Science, Florida State University, Tallahassee, FL 32306-4340, USA
    Physiol Behav 86:314-23. 2005
    ..Thus, modification of the pattern by addition of non-specific activation from mGluR2 agonist is sufficient to disrupt behavior normally driven by conspecific chemosensory stimulation...
  28. ncbi A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain
    Heather A Halem
    IPSEN Group, Milford, MA 01757, USA
    Neuroendocrinology 81:339-49. 2005
    ....
  29. ncbi Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memory
    Courtney A Miller
    Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California 92627, USA
    Neuron 47:873-84. 2005
    ..Together, these findings indicate the necessity of the AcbC ERK signaling pathway for drug-paired contextual cue memories and suggest that these strong memories can become susceptible to disruption by therapeutic agents...
  30. ncbi Type II glucocorticoid receptor involvement in habituated activation of lateral hypothalamic area orexin-A-immunopositive neurons during recurring insulin-induced hypoglycemia
    Ajay Y Kale
    Department of Basic Pharmaceutical Sciences, College of Pharmacy, The University of Louisiana at Monroe, Monroe, LA 71209, United States
    Neurosci Res 56:309-13. 2006
    ....
  31. ncbi An alternative experimental procedure for studying predator-related defensive responses
    E R Ribeiro-Barbosa
    Department of Anatomy, Institute of Biomedical Sciences, , Av. Lineu Prestes, 2415, CEP 05508-900 Sao Paulo, SP, Brazil
    Neurosci Biobehav Rev 29:1255-63. 2005
    ..Taken together, the evidence suggests the present experimental procedure as particularly suitable for analyzing the neural basis of a number of specific defensive responses...
  32. ncbi Preference for cocaine- versus pup-associated cues differentially activates neurons expressing either Fos or cocaine- and amphetamine-regulated transcript in lactating, maternal rodents
    B J Mattson
    Rutgers University, Center for Molecular and Behavioral Neuroscience, Newark, NJ 07102, USA
    Neuroscience 135:315-28. 2005
    ..We hypothesize that the expression of preference for cocaine versus pup-associated cues is made possible by the concerted activity of these regionally distributed networks of neurons that are in part specific to the preference response...
  33. ncbi Involvement of forebrain in parabrachial neuronal activation induced by aversively conditioned taste stimuli in the rat
    Kenichi Tokita
    Department of Oral Physiology, Showa University School of Dentistry, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8555, Japan
    Brain Res 1141:188-96. 2007
    ....
  34. ncbi Losartan blocks the excitatory effect of peripheral hypertonic stimulation on vasopressinergic neurons in hypothalamic paraventricular nucleus in rats: electrophysiological and immunocytochemical evidence
    Qi Zhu
    Department of Neurobiology, School of Medicine, Soochow University, 48 Renmin Road, Suzhou 215007, PR China
    Neurosci Lett 380:12-6. 2005
    ..001) as well. The result demonstrated that the vasopressinergic neurons in PVN could be excited by peripheral hypertonic stimulation, and this excitation might be mediated by angiotensin II fibers projecting from subfornical organ to PVN...
  35. ncbi Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin
    James E Blevins
    Division of Endocrinology Metabolism, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    Brain Res 993:30-41. 2003
    ..These findings support the hypothesis that oxytocin exerts a tonic stimulatory effect on the response of key neurons within the NTS to CCK and further reduce meal size...
  36. ncbi Repeated amphetamine administration outside the home cage enhances drug-induced Fos expression in rat nucleus accumbens
    Brandi J Mattson
    Behavioral Neuroscience Branch, Intramural Research Program, The National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Behav Brain Res 185:88-98. 2007
    ..We conclude that repeated amphetamine administration outside the home cage recruits the activation of enkephalin-containing nucleus accumbens neurons during sensitized amphetamine-induced psychomotor activity...
  37. ncbi Inhibition of rostral basal forebrain neurons promotes wakefulness and induces FOS in orexin neurons
    Shinsuke Satoh
    Second Department of Anatomy and Neurobiology, Kinki University School of Medicine, Osaka Sayama, Osaka 589 8511, Japan
    Eur J Neurosci 17:1635-45. 2003
    ..These functional data suggested that a sleep-generating element in the ventromedial part of the rostral basal forebrain provides an inhibitory influence on the activities of the orexin neurons in the tuberal part of the hypothalamus...
  38. ncbi Selective stimulation of striatal dopamine receptors of the D1- or D2-class causes opposite changes of fos expression in the rat cerebral cortex
    Fabio Blandini
    Laboratory of Functional Neurochemistry, IRCCS C Mondino, Pavia, Italy
    Eur J Neurosci 17:763-70. 2003
    ..Our results confirm that striatal D1 dopamine receptors play a central role in the modulation of cortical activity, thus providing additional information on the functional interaction between basal ganglia circuitry and cerebral cortex...
  39. ncbi An integrated study of heart pain and behavior in freely moving rats (using fos as a marker for neuronal activation)
    Ibrahim A M Albutaihi
    Faculty of Medical Sciences, Thoraxcenter, University Hospital of Groningen, Groningen, The Netherlands
    Neurosignals 13:207-26. 2004
    ..The role of these cerebral areas in the integration of cardiac pain is discussed in relation to the identified pathways which transmit cardiac pain...
  40. ncbi Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs
    Elisabeth B Binder
    Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Neuropsychopharmacology 29:2200-7. 2004
    ..The effects of the NT receptor antagonist were paralleled by its effects on catalepsy in olanzapine--but not haloperidol--treated animals...
  41. ncbi Dynamics of hippocampal and cortical activation during consolidation of a nonspatial memory
    Robert S Ross
    Center for Memory and Brain, Psychology Department, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 26:4852-9. 2006
    ..These findings support the view that different cortical networks support long-term memory for different types of information...
  42. ncbi Expansion of formalin-evoked Fos-immunoreactivity in rats with a spinal cord injury
    Daniel A Castellanos
    The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, R 48, Miami, FL 33136, USA
    Neurosci Res 58:386-93. 2007
    ....
  43. ncbi Corticofugal modulation of acoustically induced Fos expression in the rat auditory pathway
    Xia Sun
    Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
    J Comp Neurol 501:509-25. 2007
    ..Further investigations are needed to assess the functional implications of the morphological differences observed between the descending corticofugal projections to the thalamus and the IC...
  44. ncbi Role of amygdalo-nigral circuitry in conditioning of a visual stimulus paired with food
    Hongjoo J Lee
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 25:3881-8. 2005
    ..These experiments demonstrate a role for amygdalo-nigral circuitry in learned modulation of attention to signals for biologically significant events...
  45. ncbi Dopamine manipulation alters immediate-early gene response of striatal parvalbumin interneurons to cortical stimulation
    Jennifer T Trevitt
    Psychology Department, California State University, Fullerton, 92631, USA
    Brain Res 1035:41-50. 2005
    ..Taken together, these results indicate that DA may importantly control striatal output via influences on PV-ir interneurons. Possible mechanisms for these influences are discussed...
  46. ncbi Opioid limbic circuit for reward: interaction between hedonic hotspots of nucleus accumbens and ventral pallidum
    Kyle S Smith
    Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 27:1594-605. 2007
    ..This pattern reveals differences between limbic opioid circuits that control reward "liking" and "wanting" functions...
  47. ncbi Rapid and preferential activation of Fos protein in hypocretin/orexin neurons following the reversal of dehydration-anorexia
    Alan G Watts
    The Neuroscience Research Institute and the Department of Biological Sciences, USC College, University of Southern California, Los Angeles, California 90089 2520, USA
    J Comp Neurol 502:768-82. 2007
    ..However, when water is returned, contributions to the network controlling responses evidently come from hypocretin/orexin, but not CRH or MCH, neurons in the LHA...
  48. ncbi The rodent amygdala contributes to the production of cannabinoid-induced antinociception
    B H Manning
    Department of Neuroscience, Merck Research Laboratories, 770 Sumneytown Pike WP46 300, West Point, PA 19486 0004, USA
    Neuroscience 120:1157-70. 2003
    ..Furthermore, the results complement previous findings suggesting an overlap in neural circuitry activated by opioids and cannabinoids...
  49. ncbi Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat
    Michael S Irwig
    Department of Medicine, University of Washington, Seattle, WA, USA
    Neuroendocrinology 80:264-72. 2004
    ....
  50. ncbi Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia
    Loïs S Miraucourt
    INSERM, U929, F 63000 Clermont Ferrand, France
    J Neurosci 29:2519-27. 2009
    ....
  51. ncbi Investigating the role of substance P in photic responses of the circadian system: individual and combined actions with gastrin-releasing peptide
    Roxanne Sterniczuk
    Department of Psychology, University of Calgary, 2500 University Dr NW, Calgary, AB, T2N 1N4, Canada
    Neuropharmacology 58:277-85. 2010
    ..Distinct biochemical mechanisms that underlie behavioral phase shifts may account for the differences observed in the early- vs. late-subjective night...
  52. ncbi Possible inhibitory role of prolactin-releasing peptide for ACTH release associated with running stress
    Nao Ohiwa
    Laboratory of Exercise Biochemistry, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Ibaraki, Japan
    Am J Physiol Regul Integr Comp Physiol 292:R497-504. 2007
    ..Here we provide a novel perspective on understanding of PrRP in the endocrine-metabolic response associated with running stress...
  53. ncbi Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism
    Jason R Clapper
    Department of Pharmacology, University of California Irvine, Irvine, California, USA
    Nat Neurosci 13:1265-70. 2010
    ..Brain-impenetrant FAAH inhibitors, which strengthen this gating mechanism, might offer a new approach to pain therapy...
  54. ncbi Activation of neurons in the hypothalamic dorsomedial nucleus via hypothalamic projections of the nucleus of the solitary tract following refeeding of fasted rats
    Eva Renner
    Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary
    Eur J Neurosci 31:302-14. 2010
    ..These findings suggest that PrRP projections from the nucleus of the solitary tract contribute to the activation of ventral DMH neurons during refeeding, possibly by transferring information on cholecystokinin-mediated satiation...
  55. ncbi Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes
    Liou Y Sun
    Department of Pathology and Geriatrics Center, University of Michigan, Ann Arbor, MI 48109, USA
    Free Radic Biol Med 47:1753-61. 2009
    ..These alterations in kinase pathways may contribute to the resistance of these cells to lethal injury...
  56. ncbi Brainstem and hypothalamic regulation of sleep pressure and rebound in newborn rats
    William D Todd
    Department of Psychology, University of Iowa, USA
    Behav Neurosci 124:69-78. 2010
    ....
  57. ncbi Light induces Fos expression via extracellular signal-regulated kinases 1/2 in melanopsin-expressing PC12 cells
    Marie Louise Moldrup
    Department of Clinical Biochemistry, Faculty of Health Sciences, Bispebjerg Hospital, University of Copenhagen, Copenhagen NV, Denmark
    J Neurochem 112:797-806. 2010
    ..Our data strongly indicate that Galpha(q/11)-mediated ERK1/2 activation is essential for expression of Fos upon illumination of melanopsin-expressing PC12 cells...
  58. ncbi Inhibition of tetanically sciatic stimulation-induced LTP of spinal neurons and Fos expression by disrupting glutamate transporter GLT-1
    Zhi-Yong Wang
    Institute of Neurobiology, Institutes of Brain Sciences, Fudan University, 220 Han-Dan Road, Shanghai 200433, PR China
    Neuropharmacology 51:764-72. 2006
    ..In conclusion, glial GLT-1 may play an important role in tetanically sciatic stimulation-induced LTP of spinal nociceptive neurons via the regulation of extracellular levels of glutamate to an appropriate concentration...
  59. ncbi Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions
    David S Tait
    School of Psychology, University of St Andrews, St Andrews, Scotland, KY169RH, UK
    Psychopharmacology (Berl) 202:295-306. 2009
    ..This study examined the effect of asenapine, a novel psychopharmacologic agent being developed for schizophrenia and bipolar disorder, on cognitive dysfunction in the rat...
  60. ncbi Intra-carotid hyperosmotic stimulation increases Fos staining in forebrain organum vasculosum laminae terminalis neurones that project to the hypothalamic paraventricular nucleus
    Peng Shi
    Department of Physiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Physiol 586:5231-45. 2008
    ..001). These findings support the conclusion that PVN-projecting neurones in the DC and LM of OVLT could participate in behavioural, neuroendocrine, and sympathetic nervous system responses to body fluid hyperosmolality...
  61. ncbi Lasting changes in neuronal activation patterns in select forebrain regions of aggressive, adolescent anabolic/androgenic steroid-treated hamsters
    Lesley A Ricci
    Behavioral Neuroscience Program, Department of Psychology, 125 Nightingale Hall, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, United States
    Behav Brain Res 176:344-52. 2007
    ..A model for how persistent activation of neurons in one of these brain regions (i.e., the anterior hypothalamus) may facilitate the development of the aggressive phenotype in adolescent-AAS exposed animals is presented...
  62. ncbi Differential responses to anxiogenic drugs in a mouse model of panic disorder as revealed by Fos immunocytochemistry in specific areas of the fear circuitry
    I Sahún
    Genes and Disease Program, Center for Genomic Regulation CRG, Barcelona Biomedical Research Park PRBB, Barcelona, Spain
    Amino Acids 33:677-88. 2007
    ....
  63. ncbi Role of G(q) protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane
    Efrain E Garcia
    Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Neuropharmacology 52:1671-7. 2007
    ..These results, combined with our finding that DOI-induced FOS expression in the medial prefrontal cortex was also eliminated in Galpha(q)(-/-) mice, suggests a key role for G(q) protein in hallucinogenic drug effects...
  64. ncbi Differential disruption of nuclear volume and neuronal phenotype in the preoptic area by neonatal exposure to genistein and bisphenol-A
    Heather B Patisaul
    CIIT Centers for Health Research, 6 Davis Drive, RTP, NC 27709, United States
    Neurotoxicology 28:1-12. 2007
    ..These results suggest that acute exposure to EACs during a critical developmental period can independently alter nuclear volumes of sexually dimorphic nuclei and their phenotypic profiles in a region specific manner...
  65. ncbi Diabetes-induced chemogenic hypoalgesia is paralleled by attenuated stimulus-induced fos expression in the spinal cord of diabetic mice
    Megan S Johnson
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Pain 8:637-49. 2007
    ..This murine model may be better suited to understanding the insensate symptoms of diabetic patients in the absence of chronic pain...
  66. ncbi Identification of rat brainstem neuronal structures activated during cancer-induced anorexia
    Johan Ruud
    Division of Cell Biology, Department of Biomedicine and Surgery, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    J Comp Neurol 504:275-86. 2007
    ....
  67. ncbi Heterogeneous co-localization of AT 1A receptor and Fos protein in forebrain neuronal populations responding to acute hydromineral deficit
    Magali Grob
    Centre de Recherche en Neurosciences, , CHUL, RC 9800, 2705, boulevard Laurier, Sainte-Foy, QC, Canada G1V 4G2
    Brain Res 996:81-8. 2004
    ..This observation underlines the complexity of molecules and neurocircuits in the preoptic region that are involved in the control of acute Na(+) and water deficit...
  68. ncbi The involvement of spinal bovine adrenal medulla 22-like peptide, the proenkephalin derivative, in modulation of nociceptive processing
    Meifang Cai
    Key Provincial Laboratory of Developmental Biology and Neuroscience, College of Life Sciences, Fujian Normal University, Fuzhou, People s Republic of China, 350108
    Eur J Neurosci 26:1128-38. 2007
    ..Our study also provides evidence suggesting that BAM22 plays a role in the modulation of nociceptive processing at the spinal level under normal and inflammatory conditions...
  69. ncbi PPADS, a purinergic antagonist reduces Fos expression at spinal cord level in a mouse model of mononeuropathy
    E Borsani
    Department of Biomedical Sciences and Biotechnologies, Division of Human Anatomy, University of Brescia, Brescia, Italy
    Brain Res 1199:74-81. 2008
    ..These results suggest that PPADS reduces neuronal activation at spinal cord level and that P2 receptors are involved in the retrograde signalling progress exciting sensory spinal neurons...
  70. ncbi Hypovolemic shock: critical involvement of a projection from the ventrolateral periaqueductal gray to the caudal midline medulla
    D J Vagg
    School of Medical Sciences Anatomy and Histology, Anderson Stuart Building, The University of Sydney, NSW, Australia
    Neuroscience 152:1099-109. 2008
    ....
  71. ncbi Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, Clayton Medical Research Foundation, La Jolla, California 92037, USA
    J Neurosci 28:5806-16. 2008
    ..These findings identify the LC as an upstream component of a circuitry providing for dorsal mPFC modulation of emotional stress-induced HPA activation...
  72. ncbi Fos expression following activation of the ventral pallidum in normal rats and in a model of Parkinson's Disease: implications for limbic system and basal ganglia interactions
    Michael S Turner
    M D Ph D Program and the Neuroscience Graduate Program, Loyola University Chicago, Medical Center, Maywood, IL, USA
    Brain Struct Funct 213:197-213. 2008
    ..As the VP regulates motivation and cognition, adaptations in this system may contribute to the mood and mnemonic disorders that can accompany PD...
  73. ncbi Site-specific habituation of insulin-induced hypoglycemic induction of fos immunoreactivity in glucocorticoid receptor: immunopositive neurons in the male rat brain
    Ajay Y Kale
    Department of Basic Pharmaceutical Sciences, College of Pharmacy, The University of Louisiana at Monroe, Monroe, LA 71209, USA
    Exp Brain Res 176:260-6. 2007
    ....
  74. ncbi Amphetamine-elicited striatal Fos expression is attenuated in neurotensin null mutant mice
    Jim Fadel
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, Columbia, SC 29208, USA
    Neurosci Lett 402:97-101. 2006
    ..These data suggest that NT is required for the full activation by AMP of medial striatal neurons...
  75. ncbi Spinal neurons activated with the urethrogenital reflex in the male rat
    Lesley Marson
    Division of Urology, University of North Carolina, 2330 MBRB, CB 7052, 103 Mason Farm Road, Chapel Hill, NC 27599, USA
    Brain Res 1026:108-15. 2004
    ..These studies demonstrate the multisegmental intraspinal circuitry responsible for ejaculatory-like responses and demonstrate the potential involvement of galanin, acetylcholine and serotonin in mediation of the UG reflex...
  76. ncbi Mineralocorticoid treatment upregulates the hypothalamic vasopressinergic system of spontaneously hypertensive rats
    Luciana Pietranera
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biologia y Medicina Experimental, Buenos Aires, Argentina
    Neuroendocrinology 80:100-10. 2004
    ..These data suggest that the enhanced response of the vasopressinergic system to mineralocorticoids may contribute to the abnormal blood pressure of SHR...
  77. ncbi Rapid effects of androgens in macrophages
    W Peter M Benten
    Division of Molecular Parasitology and Centre for Biological Medical Research, Heinrich Heine University, 40225 Duesseldorf, Germany
    Steroids 69:585-90. 2004
    ..e. testosterone augments the activation of c-fos promoter and ERK1/2. Our studies demonstrate a cross-talk between the testosterone-induced nongenomic Ca2+ signaling and the genotropic signaling induced by LPS and FCS in macrophages...
  78. ncbi Lesions of the dorsal noradrenergic bundle augment the renin response to blood loss but do not alter hypothalamic Fos expression
    Rebecca L Jaworski
    Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY 14642, USA
    Brain Res Bull 63:451-9. 2004
    ..However, one or more of the forebrain regions innervated by the dorsal noradrenergic bundle may attenuate the sympathetic outflow that initiates renin release in response to hemorrhage...
  79. ncbi Activation of trigeminal nociceptive neurons by parotid PAR-2 activation in rats
    Atsufumi Kawabata
    Division of Physiology and Pathophysiology, School of Pharmaceutical Sciences, Kinki University, 3 4 1 Kowakae, Higashi Osaka 577 8502, Japan
    Neuroreport 15:1617-21. 2004
    ..Our data thus reveal that activation of PAR-2 in the parotid gland can cause activation of trigeminal nociceptive neurons via capsaicin-sensitive sensory nerves most probably by a non-inflammatory mechanism...
  80. ncbi Peripheral olfactory ensheathing cells reduce scar and cavity formation and promote regeneration after spinal cord injury
    Leanne M Ramer
    Department of Zoology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada
    J Comp Neurol 473:1-15. 2004
    ..Thus, even in a xenotransplant paradigm, LP-OECs work collaboratively with host glial cells to create an environment to ameliorate local damage and simultaneously promote a regenerative response in multiple axonal populations...
  81. ncbi Response of seizure-induced newborn neurons in the dentate gyrus of adult rats to second episode of seizures
    Wen Jiang
    Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Brain Res 1006:248-52. 2004
    ..These findings provide important evidence indicating that seizure-induced newborn neurons in freely moving adult rats are able to respond to pathophysiological stimuli in the same way as neighboring neurons do...
  82. ncbi Invasion of normal human fibroblasts induced by v-Fos is independent of proliferation, immortalization, and the tumor suppressors p16INK4a and p53
    Linda A Scott
    Beatson Institute for Cancer Research, Cancer Research UK Beatson Laboratories, Glasgow G61 1BD, United Kingdom
    Mol Cell Biol 24:1540-59. 2004
    ....
  83. ncbi Fetal brain regional responses to cerebral hypoperfusion: modulation by estrogen
    Charles E Wood
    Department of Physiology and Functional Genomics, University of Florida College of Medicine, P O Box 100274, Gainesville, FL 32610 0274, USA
    Brain Res 993:84-9. 2003
    ..The measurement of regional Fos responses using Western blot reveals a negative interaction between estrogen and BCO which might result from alterations in cerebral blood flow or metabolism...
  84. ncbi Enhanced up-regulation of corticotropin-releasing hormone gene expression in response to restraint stress in the hypothalamic paraventricular nucleus of oxytocin gene-deficient male mice
    M Nomura
    Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
    J Neuroendocrinol 15:1054-61. 2003
    ..Furthermore, neuronal activity in the BNST and the medial amygdala may be involved in this neuroendocrine regulatory system...
  85. ncbi Effects of gustatory nerve transection and regeneration on quinine-stimulated Fos-like immunoreactivity in the parabrachial nucleus of the rat
    Camille Tessitore King
    Department of Psychology, Stetson University, DeLand, Florida 32723, USA
    J Comp Neurol 465:296-308. 2003
    ....
  86. ncbi Systemic apomorphine alters HPA axis responses to interleukin-1 beta administration but not sound stress
    K M Buller
    Department of Physiology and Pharmacology, School of Biomedical Science, University of, 4072 Queensland, QLD, Australia
    Psychoneuroendocrinology 28:715-32. 2003
    ..A candidate for this site of action is the nucleus tractus solitarius catecholamine cell population and, in particular, A2 noradrenergic neurons...
  87. ncbi 2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism
    Xiao Lin
    Section of Cancer Biology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA
    Cancer Res 63:3413-7. 2003
    ....
  88. ncbi Kynurenic acid enhances electroacupuncture analgesia in normal and carrageenan-injected rats
    Yu Qiu Zhang
    Institute of Neurobiology, Fudan University, 220 Han Dan Road, 200433, Shanghai, China
    Brain Res 966:300-7. 2003
    ..t. injection of KYNA or EA alone. These results demonstrated that EAA receptor(s) antagonist could enhance EA-induced anti-nociception and anti-hyperalgesia...
  89. ncbi v-FBR-fos oncogene fails to rescue mammalian cells from growth arrest but affects the responses of human fibroblasts to heparin
    E Kolettas
    Cell and Molecular Physiology Unit, Laboratory of Experimental Physiology, University of Ioannina School of Medicine, 45110 Ioannina, Greece
    Anticancer Res 21:435-44. 2001
    ..These data show that v-FBR-fos is not sufficient to rescue mammalian cells from senescence but it can affect the responses of human fibroblasts to heparin suggesting a role of fos in cell proliferation...
  90. ncbi B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos
    D R Echlin
    Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907 1392, USA
    Oncogene 19:1752-63. 2000
    ..These findings demonstrate that B-ATF is a tissue-specific transcription factor with the potential to function as a dominant-negative to AP-1...
  91. ncbi Requirements for repression of retinoid X receptor by the oncoprotein P75gag-v-erbA and the thyroid hormone receptors
    G M Wahlström
    Department of Cellular and Molecular Biology, Karolinska Institute, Stockholm, Sweden
    Mol Endocrinol 12:645-53. 1998
    ..In addition, the data suggest that the interaction between RXR and P75gag-v-erbA on the CRBPII element is too weak to inhibit RXR from binding a ligand and therefore also to repress...
  92. ncbi Learning-stage dependent Fos expression in the rat brain during acquisition of an olfactory discrimination task
    Florence Roullet
    CESG-CNRS UMR 5170 - 15 rue H. Picardet, 21000 Dijon, France
    Behav Brain Res 157:127-37. 2005
    ..The present data suggest an early implication of the hippocampal formation and a later involvement of neocortical areas throughout different stages of a progressively acquired olfactory learning task...
  93. ncbi Ginsenosides attenuate methamphetamine-induced behavioral side effects in mice via activation of adenosine A2A receptors: possible involvements of the striatal reduction in AP-1 DNA binding activity and proenkephalin gene expression
    Eun Joo Shin
    Neurotoxicology Program, Department of Pharmacy, College of Pharmacy, Korea Institute of Drug Abuse, Kangwon National University, Chunchon 200 701, Republic of Korea
    Behav Brain Res 158:143-57. 2005
    ....
  94. ncbi Ovariotomy and persistent pain affect long-term Fos expression in spinal cord
    Xin Zhao
    Department of Anesthesiology, Ruijin Hospital, Shanghai 200025, PR China
    Neurosci Lett 375:165-9. 2005
    ..We find that ovariotomy can regulate the sensitivity to thermal stimuli and Fos protein level will change in the spinal dorsal horn. However, the alternation of Fos expression does not extremely account for the behavior...
  95. ncbi Gastric distension enhances CCK-induced Fos-like immunoreactivity in the dorsal hindbrain by activating 5-HT3 receptors
    Matthew R Hayes
    Department of Nutritional Sciences, College of Health and Human Development, The Pennsylvania State University, 126 South Henderson, University Park, PA 16802 6504, USA
    Brain Res 1088:120-30. 2006
    ..In conjunction with previous behavioral data, these results show that gastric distension enhances CCK-induced neuronal activation in the DVC by activating 5-HT3 receptors...
  96. ncbi Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's anti-inflammatory effect
    Young Bae Kwon
    Department of Pharmacology, Institute for Medical Science, Chonbuk National University Medical School, Jeonju, South Korea
    Neurosci Res 55:197-203. 2006
    ..v. idazoxan) completely blocked BVAI. Taken together, these results suggest that BVAI is mediated by peripheral activation of capsaicin-insensitive primary afferent fibers and subsequent central noradrenergic activation including the LC...
  97. ncbi Expression pattern of FOS in orexin neurons during sleep induced by an adenosine A2A receptor agonist
    Shinsuke Satoh
    Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Osaka 569 8686, Japan
    Behav Brain Res 170:277-86. 2006
    ..MCH neurons are not likely to change their activities during this sleep-promoting process...
  98. ncbi Airjet and FG-7142-induced Fos expression differs in rats selectively bred for high and low anxiety-related behavior
    Peter Salchner
    Department of Pharmacology and Toxicology, Institute of Pharmacy and Center of Molecular Biosciences Innsbruck, University of Innsbruck, Peter-Mayr-Strasse 1, A-6020 Innsbruck, Austria
    Neuropharmacology 50:1048-58. 2006
    ....
  99. ncbi Activity-dependent heterogeneous populations of nitric oxide synthase neurons in the rat dorsal raphe nucleus
    Chuma O Okere
    Department of Neurobiology and Anatomy, Drexel University College of Medicine, 2900 W Queen Lane, Philadelphia, PA 19129, USA
    Brain Res 1086:117-32. 2006
    ....
  100. ncbi Intergeniculate leaflet: contributions to photic and non-photic responsiveness of the hamster circadian system
    L Muscat
    Graduate Program in Neuroscience, Stony Brook University, Stony Brook, NY 10016, USA
    Neuroscience 140:305-20. 2006
    ....
  101. ncbi Polycose taste pre-exposure fails to influence behavioral and neural indices of taste novelty
    Sabiha K Barot
    Program of Neurobiology and Behavior, Department of Psychology, University of Washington, Seattle, WA 98195 1525, USA
    Behav Neurosci 119:1640-7. 2005
    ..Novel NaCl, on the other hand, showed patterns of FLI activation and aversion learning similar to that of novel sweet tastes. Possible reasons for the resistance of Polycose to typical pre-exposure effects are discussed...

Research Grants92

  1. Neural Analysis of Maternal Aggression
    STEPHEN GAMMIE; Fiscal Year: 2006
    ..Basic research into sex differences in aggression, then, is important to understanding the biological underpinnings of sex and gender differences in social behavior, health, and disease. ..
  2. Role of Lateral Septum in Emotional Reactivity During the Postpartum Period
    Stephen C Gammie; Fiscal Year: 2010
    ..Another benefit of this research is that it is expected to provide insights into the production of maladaptive fierce reactive aggression and open avenues for developing interventions to reduce aggression in humans. ..
  3. Role of Lateral Septum in Emotional Reactivity During the Postpartum Period
    Stephen C Gammie; Fiscal Year: 2011
    ..Another benefit of this research is that it is expected to provide insights into the production of maladaptive fierce reactive aggression and open avenues for developing interventions to reduce aggression in humans. ..
  4. Nucleus Accumbens-Mediated Feeding: Output Pathways
    Thomas R Stratford; Fiscal Year: 2010
    ....
  5. Form/function of Extended Amygdala/Accumbens Shell:CRF
    DANIEL ZAHM; Fiscal Year: 2005
    ....
  6. Estrogen Induced Neuroplasticity in the Lordosis Pathway
    LORI FLANAGAN CATO; Fiscal Year: 2004
    ..The results of these studies may illuminate the effects of estrogen on neural function. ..
  7. FUNCTIONAL CORRELATES OF MOLECULAR MARKERS OF ADAPTATION
    Galen Kaufman; Fiscal Year: 2004
    ..These findings could provide evidence regarding how the brain develops sensorimotor sets appropriate for two environments. ..
  8. Early Experience and Adult Responses to Stress
    Brian Sanders; Fiscal Year: 2003
    ..Consistent with the mission of the AREA program, this project will provide a significant training and educational opportunity for undergraduate students. ..
  9. Optimization of Bimolecular Fluorescence Complementation Probes for New Imaging F
    Tzvi Tzfira; Fiscal Year: 2010
    ..This work will improve our understanding of interactions among cellular components that are important for the health of the cell and the organism. ..
  10. Convergent Versus Parallel Striatal Afferents
    Daniel S Zahm; Fiscal Year: 2010
    ....
  11. Optimization of Bimolecular Fluorescence Complementation Probes for New Imaging F
    Tom Kerppola; Fiscal Year: 2009
    ..This work will improve our understanding of interactions among cellular components that are important for the health of the cell and the organism. ..
  12. Ontogenetic Changes in Control of Rhythmicity in rabbits
    Mario Caba; Fiscal Year: 2007
    ..g. jet lag, shift work. Once characterized, we can use this information to control circadian rhythms in circumstances where it is disrupted. ..
  13. Antipsychotic Actions in Models of NMDA Hypofunction
    Gary Duncan; Fiscal Year: 2007
    ....
  14. Estrogen and Inflammation in TMD Pain
    DAVID BEREITER; Fiscal Year: 2006
    ..This information may lead to a better understanding of how the brain integrates pain-like signals relevant for TMD in women ..
  15. Renal Transporters and Fetal Neuroendocrinology
    Charles Wood; Fiscal Year: 2009
    ..This proposal is aimed at providing a novel understanding of fetal stress hormones and novel approaches towards manipulating the fetal stress response. ..
  16. Endocrine Disruption of the Hypothalamic Signaling That Regulates Puberty
    Heather B Patisaul; Fiscal Year: 2010
    ..AIM 4: Characterize the impact of neonatal BPA, GEN, DPN or PPT on AVPV volume, AVPV ER and kisspeptin content, and hormone-stimulated GnRH neuronal activation post-puberty. ..
  17. SEX-RELATED OPIATE AND AUTONOMIC MECHANISMS IN TMD PAIN
    DAVID BEREITER; Fiscal Year: 2001
    ..The shorter term goal is to define the involvement of opiate and vagal afferent nerve mechanisms at the level of the trigeminal brainstem complex that may have analgesic effects after inflammation of the TMJ region. ..
  18. TRIGEMINAL CONTROL OF ADRENAL AUTONOMIC FUNCTION
    DAVID BEREITER; Fiscal Year: 1990
    ..This proposal focuses on the spinal trigeminal system as a model to assess the degree of overlap between the sensory- discriminative and the autonomic aspects of nociception...
  19. MECHANISMS OF CANNABINOIDS ANTIEMETIC ACTIONS
    NISSAR DARMANI; Fiscal Year: 2001
    ..The results will define an important role for the cannabinoid receptors in the vomiting circuits and may implicate an antiemetic role for the endogenous cannabinoids. ..
  20. TRIGEMINAL CONTROL OF ADRENAL AUTONOMIC FUNCTION
    DAVID BEREITER; Fiscal Year: 1993
    ....
  21. OPIATE MODULATION OF CORNEA PAIN PATHWAYS
    DAVID BEREITER; Fiscal Year: 1999
    ....
  22. NEUROPEPTIDES AND THEIR PHYSIOLOGICAL CONTROL
    ALAN WATTS; Fiscal Year: 1999
    ....
  23. Neuron Phenotype Changes During Lactation
    Gloria Hoffman; Fiscal Year: 2005
    ..abstract_text> ..
  24. NEUROTROPHIN CONTROL OF REM SLEEP
    Jack Yamuy; Fiscal Year: 2004
    ..This concerted set of experiments will be critical in elucidating the role that neurotrophins play in the control of REM sleep. ..
  25. Optimization of Bimolecular Fluorescence Complementation Probes for New Imaging F
    Tom Kerppola; Fiscal Year: 2009
    ..This work will improve our understanding of interactions among cellular components that are important for the health of the cell and the organism. ..
  26. FETAL REFLEX RESPONSES TO CEREBRAL HYPOPERFUSION
    Charles Wood; Fiscal Year: 1999
    ..Improvement of our knowledge of the rnle of prostanoids in the control of fetal blood pressure is also quite important in light of the use of prostaglandin synthase inhibitors clinically for various reasons, including tocolysis. ..
  27. NEUROPEPTIDES AND THEIR PHYSIOLOGICAL CONTROL
    ALAN WATTS; Fiscal Year: 2002
    ..hypertension, obesity, eating disorders) currently of central importance to human health, that have perturbed homeostatic regulation at the core of their etiology. ..
  28. CONVERGENT VS PARALLEL STRIATAL DOPAMINERGIC AFFERENTS
    DANIEL ZAHM; Fiscal Year: 1991
    ..In concert, the two components of the proposed investigation should contribute to bridging conceptual gaps separating structure and function in striatum...
  29. CONVERGENT VS PARALLEL STRIATAL DOPAMINERGIC AFFERENTS
    DANIEL ZAHM; Fiscal Year: 2000
    ..The third aim will use a complex set of pharmacologically-mediated changes in specific gene expression to distinguish among and characterize different populations of striatal NT neurons. ..
  30. Estrogen Influences on Fetal Adrenocorticotropin
    Charles Wood; Fiscal Year: 2006
    ..abstract_text> ..
  31. NEURAL MECHANISMS OF ANOREXIA
    ALAN WATTS; Fiscal Year: 2006
    ..abstract_text> ..
  32. Spatial aspects of coding in piriform cortex
    KURT ILLIG; Fiscal Year: 2007
    ..abstract_text> ..
  33. 5-HT3 receptor mediation of 5-HT & CCK-induced satiation
    Matthew Hayes; Fiscal Year: 2005
    ....
  34. FETAL CARDIOVASCULAR AND ENDOCRINE REFLEX RESPONSES
    Charles Wood; Fiscal Year: 2007
    ..The results will identify the processes within the reflex pathway that can be manipulated pharmacologically and therefore enhance fetal survival during hypotensive stress. ..
  35. FETAL CARDIOVASCULAR AND ENDOCRINE REFLEX RESPONSES
    Charles Wood; Fiscal Year: 2005
    ..abstract_text> ..