htlv ii antibodies

Summary

Summary: Antibodies reactive with the HTLV-II ANTIGENS.

Top Publications

  1. ncbi Molecular characterization of human T-cell lymphotropic virus type 2 (HTLV-II) from people living in urban areas of Sao Paulo city: evidence of multiple subtypes circulation
    Patricia Novoa
    Institute of Infectious Diseases Emilio Ribas, Sao Paulo, Brazil
    J Med Virol 79:182-7. 2007
  2. ncbi [Sero-epidemiological study on the human T-cell leukaemia virus type I/II infection in the east coastal areas of Fujian province]
    Hui rong Wang
    Fujian Province Center for Disease Control and Prevention, Fuzhou 350001, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:428-30. 2004
  3. ncbi Unusually high incidence of positive HTLV I/II results among young female organ donors in the peripartum period
    Ernesto P Molmenti
    Baylor University Medical Center, Transplantation Services, Dallas, Texas 75246, USA
    Dig Dis Sci 47:2383-5. 2002
  4. ncbi Effectiveness of human T-lymphotropic virus (HTLV) recipient tracing (lookback) and the current HTLV-I and -II confirmatory algorithm, 1999 to 2004
    S L Stramer
    American Red Cross, Biomedical Services Scientific Support Office, Gaithersburg, Maryland 20877, USA
    Transfusion 46:703-7. 2006
  5. pmc Post-transplantation HTLV-1 myelopathy in three recipients from a single donor
    J J Zarranz Imirizaldu
    Department of Neurology, Hospital of Cruces, s n CP 48903 Baracaldo, Vizcaya, Spain
    J Neurol Neurosurg Psychiatry 74:1080-4. 2003
  6. ncbi HTLV-1 infection is frequent among out-patients with pulmonary tuberculosis in northern Lima, Peru
    K Verdonck
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Tuberc Lung Dis 11:1066-72. 2007
  7. ncbi Prevalence and molecular characterization of human T cell leukemia virus type 2 in a group of intravenous drug users coinfected with HIV type 1 in Portugal
    Ana Filipa Silva
    Laboratório de Referência da SIDA Centro de Virologia, Instituto Nacional de Saude, P 1649 016 Lisbon, Portugal
    AIDS Res Hum Retroviruses 21:249-55. 2005
  8. ncbi HTLV infection among young injection and non-injection heroin users in Spain: prevalence and correlates
    Luis de la Fuente
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, C Sinesio Delgado 6, 28029 Madrid, Spain
    J Clin Virol 35:244-9. 2006
  9. ncbi Is seroprevalence of HTLV-I/II among blood donors in India relevant?
    Harsh Kumar
    Department of Transfusion Medicine, Armed Forces Medical College, Pune 411 040
    Indian J Pathol Microbiol 49:532-4. 2006
  10. ncbi Evaluation of surrogate markers for human immunodeficiency virus infection among blood donors at the blood bank of "Hospital Universitário Regional Norte do Paraná", Londrina, PR, Brazil
    Edna Maria Vissoci Reiche
    Departamento de Patologia Aplicada, Legislação e Deontologia, Centro de Ciencias da Saude, Universidade Estadual de Londrina, Londrina, PR, Brasil
    Rev Inst Med Trop Sao Paulo 45:23-7. 2003

Scientific Experts

Detail Information

Publications81

  1. ncbi Molecular characterization of human T-cell lymphotropic virus type 2 (HTLV-II) from people living in urban areas of Sao Paulo city: evidence of multiple subtypes circulation
    Patricia Novoa
    Institute of Infectious Diseases Emilio Ribas, Sao Paulo, Brazil
    J Med Virol 79:182-7. 2007
    ..This is the first time HTLV-II subtype b has been described in Brazil. However, further studies, such as a complete nucleotide DNA sequencing, need to be done to confirm these findings...
  2. ncbi [Sero-epidemiological study on the human T-cell leukaemia virus type I/II infection in the east coastal areas of Fujian province]
    Hui rong Wang
    Fujian Province Center for Disease Control and Prevention, Fuzhou 350001, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:428-30. 2004
    ..To study the seroprevalence of human T-cell leukaemia virus type I/II (HTLV-I/II) infection in adult population in the east coastal areas of Fujian and to explore the possible risk factors of HTLV-I/II...
  3. ncbi Unusually high incidence of positive HTLV I/II results among young female organ donors in the peripartum period
    Ernesto P Molmenti
    Baylor University Medical Center, Transplantation Services, Dallas, Texas 75246, USA
    Dig Dis Sci 47:2383-5. 2002
    ..Further confirmatory tests may be difficult to obtain because of time and economic constraints associated with organ procurement...
  4. ncbi Effectiveness of human T-lymphotropic virus (HTLV) recipient tracing (lookback) and the current HTLV-I and -II confirmatory algorithm, 1999 to 2004
    S L Stramer
    American Red Cross, Biomedical Services Scientific Support Office, Gaithersburg, Maryland 20877, USA
    Transfusion 46:703-7. 2006
    ..This study reports on the efficacy of an investigational human T-lymphotropic virus (HTLV)-I and -II lookback program in the context of differing confirmatory testing algorithms...
  5. pmc Post-transplantation HTLV-1 myelopathy in three recipients from a single donor
    J J Zarranz Imirizaldu
    Department of Neurology, Hospital of Cruces, s n CP 48903 Baracaldo, Vizcaya, Spain
    J Neurol Neurosurg Psychiatry 74:1080-4. 2003
    ..The need is considered for the implementation of compulsory screenings for HTLV antibodies on organ donors and on blood banks...
  6. ncbi HTLV-1 infection is frequent among out-patients with pulmonary tuberculosis in northern Lima, Peru
    K Verdonck
    Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Tuberc Lung Dis 11:1066-72. 2007
    ..Tuberculosis (TB) and human T-lymphotropic virus 1 (HTLV-1) are frequent in Peru. The prevalence of HTLV-1 among Peruvian TB patients is unknown...
  7. ncbi Prevalence and molecular characterization of human T cell leukemia virus type 2 in a group of intravenous drug users coinfected with HIV type 1 in Portugal
    Ana Filipa Silva
    Laboratório de Referência da SIDA Centro de Virologia, Instituto Nacional de Saude, P 1649 016 Lisbon, Portugal
    AIDS Res Hum Retroviruses 21:249-55. 2005
    ....
  8. ncbi HTLV infection among young injection and non-injection heroin users in Spain: prevalence and correlates
    Luis de la Fuente
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, C Sinesio Delgado 6, 28029 Madrid, Spain
    J Clin Virol 35:244-9. 2006
    ....
  9. ncbi Is seroprevalence of HTLV-I/II among blood donors in India relevant?
    Harsh Kumar
    Department of Transfusion Medicine, Armed Forces Medical College, Pune 411 040
    Indian J Pathol Microbiol 49:532-4. 2006
    ..The prevalence of HTLV-I/II carriers in India seems to be negligible and is not a major public health hazard. Hence, routine screening of Indian blood donors for antibody to HTLV-I/II is not warranted due to its low prevalence in India...
  10. ncbi Evaluation of surrogate markers for human immunodeficiency virus infection among blood donors at the blood bank of "Hospital Universitário Regional Norte do Paraná", Londrina, PR, Brazil
    Edna Maria Vissoci Reiche
    Departamento de Patologia Aplicada, Legislação e Deontologia, Centro de Ciencias da Saude, Universidade Estadual de Londrina, Londrina, PR, Brasil
    Rev Inst Med Trop Sao Paulo 45:23-7. 2003
    ....
  11. ncbi Heterogeneous geographic distribution of human T-cell lymphotropic viruses I and II (HTLV-I/II): serological screening prevalence rates in blood donors from large urban areas in Brazil
    Bernadette Catalan-Soares
    Fundação Hemominas, Belo Horizonte, Brazil
    Cad Saude Publica 21:926-31. 2005
    ..0/1,000 in São Luiz, Maranhão State, in the Northeast. EIA prevalence rates are lower in the South and higher in the North and Northeast. The reasons for such heterogeneity may be multiple and need further studies...
  12. ncbi High prevalence of HTLV-I and HTLV-II among blood donors in Argentina: a South American health concern
    Mirna M Biglione
    Centro Nacional de Referencia para el SIDA CNRS, Departamento Microbiologia, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    AIDS Res Hum Retroviruses 21:1-4. 2005
    ..01%) were born in HTLV-I/II South American endemic areas. Although Argentina has been considered a nonendemic country for HTLV-I/II, the need for systematic screening for such infection became imperative based on the present study...
  13. ncbi Low prevalence of antibodies to human T-lymphotropic virus-I/II among blood donors in eastern Saudi Arabia
    Naglaa A Fawaz
    Department of Hematology, King Faisal University, Damman, Saudi Arabia
    Am J Infect Control 33:189-91. 2005
    ..Although the very low prevalence of HTLV-I/II among Saudi donors does not support routine screening, screening of donors from other nationalities may be initiated, especially those from HTLV-I/II endemic areas...
  14. ncbi [HTLV 1/2 infection: prenatal performance as a disease control strategy in State of Mato Grosso do Sul]
    Márcia Maria Ferrairo Janini Dal Fabbro
    Instituto de Pesquisas, Ensino e Diagnósticos, Associação de Pais e Amigos dos Excepcionais de Campo Grande, Campo Grande, MS
    Rev Soc Bras Med Trop 41:148-51. 2008
    ..Comorbidities were found in 17% (26/153), among whom 3.3% (5/153) had HIV (p<0.000002). The authors emphasize the importance of identifying pregnant women with HTLV 1/2 infection, as a strategy for disease control and prevention...
  15. doi Serological patterns and temporal trends of HTLV-1/2 infection in high-risk populations attending Public Health Units in São Paulo, Brazil
    Fabrício Jacob
    Immunology Department, Instituto Adolfo Lutz, Av Dr Arnaldo 355, 11 andar, 01246 902 São Paulo, SP, Brazil
    J Clin Virol 42:149-55. 2008
    ..HTLV-1/2 diagnosis in high-risk populations from São Paulo, Brazil has been problematic due a high proportion of seroindeterminate results...
  16. ncbi Human T-cell lymphotropic virus types I and II infections in a cohort of patients with neurological disorders in Belém, Pará, Brazil
    Olinda Macedo
    Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministerio da Saude, Belem, Para, Brasil
    Rev Inst Med Trop Sao Paulo 46:13-7. 2004
    ..These findings provide evidence that both HTLV-I and HTLV-II play a role in the development of chronic myelopathy in Belém, Pará, Northern Brazil...
  17. ncbi Screening for viral markers in volunteer and replacement blood donors in West Africa
    F Sarkodie
    Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana
    Vox Sang 80:142-7. 2001
    ..No p24 antigen-positive/anti-HIV-negative donations were found. The prevalence of HTLV-I/II was generally low (0.5%). CONCLUSION: All blood donations should be screened for hepatitis B virus (HBV), HIV and HCV markers...
  18. pmc Seroprevalence and molecular epidemiology of human T-Cell leukemia virus type 1 (HTLV-1) and HTLV-2 in blood donors from Dakar, Senegal
    Saliou Diop
    Unité d Epidémiologie et Physiopathologie des Virus Oncogènes, Département Ecosytèmes et Epidémiologie des Maladies Infectieuses, Batiment Lwoff, Institut Pasteur, 25 28 Rue du Dr Roux, 75724 Paris, Cedex 15, France
    J Clin Microbiol 44:1550-4. 2006
    ..These data highlight the problem of transfusion safety in this area where HTLV-1-associated lymphoproliferative and neurological diseases are endemic...
  19. ncbi Human T-cell lymphotropic virus type II in Guaraní Indians, Southern Brazil
    Marcio Menna-Barreto
    Hospital Sao Lucas, Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, Brasil
    Cad Saude Publica 21:1947-51. 2005
    ..76%) showed positive anti-HTLV-II antibodies (enzyme-linked immunosorbent assay and Western blot). This preliminary report is the first seroepidemiological study showing HTLV-II infection among Indians in the South of Brazil...
  20. ncbi Prevalence of human T-lymphotropic virus type I and type II antibody among blood donors in Eastern Saudi Arabia
    Zahoor Ul-Hassan
    Department of Laboratory and Blood Bank, King Fahad Hospital and Tertiary Care Center, Al Hofuf, Al Hasa, Kingdom of Saudi Arabia
    Saudi Med J 25:1419-22. 2004
    ..The aim of this study is to circumvent the risk of transmission through blood transfusion and to describe the prevalence of HTLV-I/II antibody among blood donors of Al-Hasa region and the cost effectiveness of screening blood donors...
  21. ncbi Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I
    Karen Yao
    Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurologic Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Infect Dis 193:427-37. 2006
    ..Our findings warrant further investigation of the possible clinical outcomes associated with WB seroindeterminate status...
  22. ncbi The seroepidemiology of human T-lymphotropic viruses: types I and II in Europe: a prospective study of pregnant women
    Graham P Taylor
    Faculty of Medicine, Wright Fleming Institute, Imperial College, Norfolk Place, London, United Kingdom
    J Acquir Immune Defic Syndr 38:104-9. 2005
    ..Most data on the seroprevalence of HTLV-I and HTLV-II in Europe are from studies of low-risk blood donors or high-risk injection drug users (IDUs). Little is known about the general population...
  23. ncbi HTLV-2 horizontal and vertical transmission in a family from a Brazilian urban area: seroepidemiological, clinical and molecular study
    Bernadette Catalan-Soares
    Fundação Centro de Hematologia e Hemoterapia de Minas Gerais Hemominas, Minas Gerais, Brazil
    AIDS Res Hum Retroviruses 21:521-6. 2005
    ..Analyzing both LTR and env regions, the family's sequences clustered with isolates of Brazilian intravenous drug users and transfusion transmitted virus...
  24. ncbi Seroprevalence of human T cell leukemia virus in HIV antibody-negative populations in rural Cameroon
    Ana Machuca
    Division Diagnosticos, Quimica Farmaceutica Bayer, Madrid, Spain
    Clin Infect Dis 40:1673-6. 2005
    ..Of the 88 serum samples that the enzyme immunoassay found to be repeatedly reactive, the HTLV status of 49 samples was confirmed by Western blot assay to be HTLV type I, and the status of 6 samples was confirmed to be HTLV type II...
  25. pmc Molecular evidence for infection by HTLV-2 among individuals with negative serological screening tests for HTLV antibodies
    R Ishak
    Laboratorio de Virologia, Centro de Ciencias Biologicas, Universidade Federal do Para, Belem, Para, Brasil
    Epidemiol Infect 135:604-9. 2007
    ....
  26. ncbi High seroprevalence of anti-HTLV-I/II antibodies among solid organ donors necessitates confirmatory testing
    Marek J Nowicki
    National Institute of Transplantation, Los Angeles, CA 90057, USA
    Transplantation 82:1210-3. 2006
    ..Confirmatory testing is not routinely performed, and the number of false positive organ donors is unknown...
  27. ncbi [Prevalence, risk factors and genetic characterization of human T-cell lymphotropic virus types 1 and 2 in patients infected with human immunodeficiency virus type 1 in the cities of Ribeirão Preto and São Paulo]
    Walter Kleine Neto
    Fundação Pró Sangue, Hemocentro de São Paulo, Av Dr Enéas Carvalho de Aguiar 155, Sao Paulo, SP
    Rev Soc Bras Med Trop 42:264-70. 2009
    ..Among the 12 HTLV type 2 samples, seven were from injected drug users, thus indicating that this route is an important risk factor for HTLV type 2 transmission among our population infected with HIV type 1...
  28. pmc Epidemiology of human T-cell lymphotropic virus type 1 infection in blood donors, Israel
    Shmuel Stienlauf
    Sheba Medical Center, Tel Hashomer, Israel
    Emerg Infect Dis 15:1116-8. 2009
    ..In donors originating from Eastern Europe, the Middle East, and Latin America, prevalences are 7.7, 14.6, and 20.4, respectively. HTLV-1 prevalence may be high outside areas where HTLV-1 previously was known to be endemic...
  29. ncbi Confirming the presence of HTLV-1 infection and the absence of HTLV-2 in blood donors from Arequipa, Peru
    Nadia Carmela Santos Quispe
    Hospital Goyeneche, Arequipa, Peru
    Rev Inst Med Trop Sao Paulo 51:25-9. 2009
    ....
  30. doi Seroprevalence of human T lymphtropic virus (HTLV) among tissue donors in Iranian tissue bank
    Babak Arjmand
    Iranian Tissue Bank Research and Preparation Center and Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Imam Khomeini Hospital, Keshavarz Blvd, Tehran, Iran
    Cell Tissue Bank 10:247-52. 2009
    ....
  31. doi Seroprevalence of human T-lymphotropic virus type 1 and 2 in Korean blood donors
    So Yong Kwon
    Blood Transfusion Research Institute, Korean Red Cross, Seoul, Korea
    J Med Virol 80:1864-7. 2008
    ..007%. Based on the results of this study, an extended study will be conducted to evaluate whether introduction of HTLV screening is necessary in Korea...
  32. doi Evaluation of a new, fully automated immunoassay for detection of HTLV-I and HTLV-II antibodies
    Xiaoxing Qiu
    Abbott Diagnostics, AIDS Research and Retrovirus Discovery, Abbott Park, Illinois 60064 6015, USA
    J Med Virol 80:484-93. 2008
    ..6) populations. Based on the excellent specificity and sensitivity, the new ARCHITECT rHTLV-I/II assay should be an effective test for the diagnosis of HTLV-I/II infection and also for blood donor screening...
  33. doi Evaluation of a new screening assay for HTLV-1 and -2 antibodies for large-scale use
    Kerstin Malm
    Department of Laboratory Medicine, Microbiology, Orebro University Hospital, 70185 Orebro, Sweden
    J Med Virol 82:1606-11. 2010
    ..Taken together, the overall specificity was 99.8%. The assay was sensitive, specific and appropriate for the large-scale screening of samples for HTLV-1/2 antibodies...
  34. ncbi Performances of HTLV serological tests in diagnosing HTLV infection in high-risk population of São Paulo, Brazil
    Fabrício Jacob
    Seção de Imunologia, Instituto Adolfo Lutz, Sao Paulo, SP, Brasil
    Rev Inst Med Trop Sao Paulo 49:361-4. 2007
    ....
  35. ncbi Comparison of four commercial screening assays for the diagnosis of human T-cell lymphotropic virus types 1 and 2
    Carolina A Berini
    Centro Nacional de Referencia para el SIDA, Departamento de Microbiologia, Parasitología e Immunología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, Piso 11, C1121ABG Buenos Aires, Argentina
    J Virol Methods 147:322-7. 2008
    ..These results should be considered for choosing the most accurate serological screening assays in order to obtain an optimal efficiency of the current algorithm for HTLV-1/2 diagnosis...
  36. ncbi Serologial screening of human T cell lymphotropic virus I and II (HTLV I/II) in blood banks by immunoblotting and enzyme-immuno assays: to demand or to defeat?
    Maha I Sh Kawashti
    Microbiology and Immunology Department, Faculty of Medicine for Girls, AI Azhar University, Cairo, Egypt
    Egypt J Immunol 12:137-42. 2005
    ..As screening for HTLV I/II is still mandatory, it could be done on pools of sera rather than on individual serum samples, after standardization of a pooling protocol, to fulfill coast-effectiveness and reduce the coasts by 90-95%...
  37. ncbi [Evaluation of new fourth-generation human immunodeficiency virus antigen and antibody detection assay with enzyme-linked fluorescent immunoassay]
    Takako Shima
    Department of Biology, Kanagawa Prefectural Institute of Public Health
    Kansenshogaku Zasshi 81:562-72. 2007
    ..DUOII has sufficient specificity and sensitivity for HIV screening, and detects primary infection sooner than other assays. These results indicate that DUOII is useful and reliable in HIV screening...
  38. ncbi Hospital-based surveillance for HTLV-1/2 infections in Spain
    Carlos Toro
    Service of Infectious Diseases, Hospital Carlos III, Madrid, Spain
    AIDS Res Hum Retroviruses 23:1075-7. 2007
    ..However, a rapidly growing population of immigrants from HTLV-1-endemic areas in Spain could modify this pattern and periodic surveillance studies including both natives and immigrants are warranted...
  39. ncbi Difficulties in the diagnosis of HTLV-2 infection in HIV/AIDS patients from Brazil: comparative performances of serologic and molecular assays, and detection of HTLV-2b subtype
    Helena Kaminami Morimoto
    Departamento de Patologia, Análises Clínicas e Toxicológicas, Centro de Ciencias da Saude, Universidade Estadual de Londrina, Parana, Brasil
    Rev Inst Med Trop Sao Paulo 49:225-30. 2007
    ..These results emphasize the need of improving serologic tests for detecting truly HTLV-2 infected patients from Brazil, and confirm the presence of HTLV-2b subtype in the South of this country...
  40. ncbi Potential impact of AUSFTA on Australia's blood supply. Comment
    Wolfgang Frenzel
    Med J Aust 186:427-8; author reply 430. 2007
  41. ncbi Unusual finding of HTLV-I infection among Amazonian Amerindians
    Luis Isamu Barros Kanzaki
    Laboratory of Molecular Pharmacology, Faculty of Health Sciences, University of Brasilia, Brasilia, DF, Brazil
    Arch Med Res 38:897-900. 2007
    ..Also, the very low prevalence of HTLV type I infection among these ethnic groups probably indicates contamination by blood transfusion (external transmission route)...
  42. ncbi Human T-cell lymphotropic virus types I and II (HTLV-I and -II) infection among seroindeterminate cases in Argentina
    Carolina A Berini
    Centro Nacional de Referencia para el SIDA, Departamento de Microbiologia, Parasitología e Immunología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    J Med Virol 79:69-73. 2007
    ..However, when seroreactivity to Env and Gag proteins are observed on the WB and especially in at-risk populations, HTLV infection should be suspected; such individuals should be followed-up and retested...
  43. ncbi Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil
    Maísa Aparecida Ribeiro
    Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil
    Rev Panam Salud Publica 27:330-7. 2010
    ....
  44. ncbi Prevalence of HIV-1 non-B subtypes, syphilis, HTLV, and hepatitis B and C viruses among immigrant sex workers in Madrid, Spain
    Maite Gutiérrez
    Microbiology Unit, Hospital Carlos III, Madrid, Spain
    J Med Virol 74:521-7. 2004
    ..A relatively high proportion of immigrant sex workers in Madrid were infected with HIV-1 and syphilis, whereas infections with hepatitis viruses or HTLV were uncommon...
  45. ncbi Antigenic mixture of synthetic peptides for the immunodiagnosis of HTLV I/II infection
    Yadaris Márquez Bocalandro
    Department of Retroviruses, National Center for Scientific Research, Havana, Cuba
    J Immunoassay Immunochem 25:205-14. 2004
    ..The highest sensitivity and specificity was obtained with mixture 1, which could be very useful in the immunodiagnostic of HTLV infection...
  46. ncbi Differential serological diagnosis of HTLV-I and HTLV-II infection by external membrane protein peptide-based enzyme immunoassays
    H H Lee
    Department of Haematology, University of Cambridge, UK
    Clin Diagn Virol 8:9-16. 1997
    ..It is critical to make a differential diagnosis of the two viruses...
  47. ncbi [Determination of anti-HTLV-I/II antibodies: Experience in 28,897 blood donations in Buenos Aires]
    J L Blejer
    División Medicina Transfusional, Instituto de Cardiologia y Cirugia Cardiovascular, Buenos Aires, Argentina
    Sangre (Barc) 40:447-51. 1995
    ..This study could serve as a measure of the infection in the general population...
  48. ncbi Detection of human T-lymphotropic virus type-I/II env antibodies by immunoassays using recombinant fusion proteins
    D L Rudolph
    Retrovirus Diseases Branch, Centers for Disease Control, Atlanta, Georgia 30333
    Diagn Microbiol Infect Dis 17:35-9. 1993
    ..We, therefore, conclude that although rEnv-93 is highly sensitive for detection of env protein, it has the potential to yield some false-positive reactions presumably due to the conserved nature of retroviral transmembrane epitopes...
  49. ncbi Serological speciation of human T-cell leukaemia virus infections using synthetic peptide antigens
    J H Tosswill
    Virus Reference Division, Central Public Health Laboratory, London, England
    J Med Virol 40:83-5. 1993
    ..However, they should only be applied to sera that have been confirmed by Western blot or other methods as anti-HTLV-I/II positive. Even then they may fail to speciate sera from non-Japanese, non-Afrocaribbean populations...
  50. pmc Evaluation of two commercial human T-cell lymphotropic virus western blot (immunoblot) kits with problem specimens
    D Gallo
    Viral and Rickettsial Disease Laboratory, State of California Department of Health Services, Berkeley 94704
    J Clin Microbiol 32:2046-9. 1994
    ..If all samples not reacting with this protein were interpreted as WB negative, regardless of other bands, the specificity would improve to 90% for CBC and 86% for DBL...
  51. ncbi Human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in São Paulo, Brazil
    R B Domingues
    Department of Neurology, University of Sao Paulo School of Medicine, Brazil
    Clin Infect Dis 20:1540-2. 1995
    ..Despite the presence of HTLV-II virus in Brazil, all patients whose serum was tested by PCR were found to be infected with the HTLV-I virus...
  52. ncbi Frequent detection of antibodies against HTLV antigens in patients with AIDS-related non-Hodgkin lymphoma
    G Zehender
    Clinica delle Malattie Infettive, University of Milan, Italy
    AIDS Res Hum Retroviruses 11:823-7. 1995
    ..These data suggest that HTLV-II or a closely homologous retrovirus infects a high proportion of patients with AIDS-associated NHL...
  53. ncbi Serological discrimination between HTLV-I and HTLV-II antibodies by ELISA using synthetic peptides as antigens
    Y Washitani
    Fukuoka Red Cross Blood Center, Japan
    Int J Cancer 49:173-7. 1991
    ....
  54. ncbi Infectious transmission of human T-cell lymphotropic virus type II in rabbits
    G L Cockerell
    Department of Pathology, Colorado State University, Fort Collins 80523
    Blood 78:1532-7. 1991
    ..These results provide the first evidence of HTLV-II infection in a species other than humans, and demonstrate the usefulness of the rabbit as an animal model to study the biologic response to different isolates of this human retrovirus...
  55. ncbi Identification of immunodominant epitopes in envelope glycoprotein of human T lymphotropic virus type II
    R B Lal
    Retrovirus Diseases Branch, Centers for Disease Control, Atlanta, Georgia 30333
    Virology 186:274-9. 1992
    ..We conclude that peptides Env-20(85-102) and Env-202(173-209) represent the type-specific immunodominant epitopes of HTLV-II external glycoprotein...
  56. ncbi Antibody to human retroviruses among drug users in three east coast American cities, 1972-1976
    R J Biggar
    Viral Epidemiology Section, National Cancer Institute, Bethesda, Maryland 20852
    J Infect Dis 163:57-63. 1991
    ..Therefore, HTLV (probably HTLV-II) has been a common infection of drug users for many years but adverse outcomes following infection were not demonstrated...
  57. ncbi Human T-cell leukemia virus type-I/II (HTLV-I/II) serologic testing: the importance of assaying for the full complement of viral antigens
    D M Aboulafia
    Department of Medicine, Virginia Mason Medical Center, Seattle, Washington
    Viral Immunol 5:105-11. 1992
    ..Current HTLV-I/II ELISA kits may yield false negative results. Additional research into the development of rapid detection cost-efficient assays that test for the full compliment of viral antigens is needed...
  58. ncbi Human T lymphotropic virus types I- and II-specific antibody-dependent cellular cytotoxicity: strain specificity and epitope mapping
    X Q Zhang
    Infectious Disease Division, University of Colorado Health Sciences Center, Denver 80262
    J Infect Dis 165:805-12. 1992
    ....
  59. pmc Sensitivity and specificity of a recombinant transmembrane glycoprotein (rgp21)-spiked western immunoblot for serological confirmation of human T-cell lymphotropic virus type I and type II infections
    R B Lal
    Retrovirus Diseases Branch, Center for Disease Control, Atlanta, Georgia 30333
    J Clin Microbiol 30:296-9. 1992
    ..Thus, specimens exhibiting reactivity with rgp21 in the absence of reactivity with native gp46 and/or gp61/68 by Western blot should be tested further by a radioimmunoprecipitation assay to verify HTLV type I or type II infection...
  60. ncbi Health care worker exposure to HIV-1 and HTLV I-II in critically ill, resuscitated emergency department patients
    C Lewandowski
    Department of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan
    Ann Emerg Med 21:1353-9. 1992
    ..The purpose was to determine the seroprevalence of HIV-1 and HTLV I-II in patients undergoing ED resuscitations, the magnitude of health care worker exposure, and risk factors associated with infection...
  61. ncbi Laboratory characterization of human T cell lymphotropic virus types 1 (HTLV-1) and 2 (HTLV-2) infections in blood donors from Sao Paulo, Brazil
    A A Segurado
    Department of Infectious Diseases, School of Medicine, University of Sao Paulo, Brazil
    Am J Trop Med Hyg 57:142-8. 1997
    ....
  62. ncbi Detection of HTLV-I in clinical specimens
    M A Beilke
    Section of Infectious Diseases, Tulane University School of Medicine, New Orleans, LA 70112
    J Virol Methods 40:133-44. 1992
    ..This review summarizes the techniques currently in use to screen for HTLV-I/II antibodies, as well as methods to detect viral genome and/or gene products in blood and tissue specimens...
  63. ncbi Human T lymphotropic virus types I and II proviral sequences in Argentinian blood donors with indeterminate Western blot patterns
    A M Mangano
    Laboratorio de Biología Celular y Retrovirus, Hospital Nacional de Pediatria J P Garrahan, Buenos Aires, Argentina
    J Med Virol 74:323-7. 2004
    ..However, seroreactivity to env proteins, in particular to GD21, may indicate infection and a follow-up study of each seroreactive blood donor should be considered...
  64. pmc Isolation of human T-cell lymphotropic virus type 2 from Guaymi Indians in Panama
    M D Lairmore
    Retrovirus Disease Branch, Centers for Disease Control, Atlanta, GA 30333
    Proc Natl Acad Sci U S A 87:8840-4. 1990
    ....
  65. ncbi Is seroprevalence of HTLV-I/II among blood donors in Lebanon relevant?
    Hala Tamim
    Department of Epidemiology and Biostatistics, Faculty of Health Sciences, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Infect Control 32:220-3. 2004
    ....
  66. pmc Detection of human T-lymphotropic virus (HTLV) tax sequences in New York City blood donors seronegative for HTLV types 1 and 2
    Charlene S Dezzutti
    Division of AIDS, STD, and TB Laboratory Research, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Clin Diagn Lab Immunol 10:715-7. 2003
    ..All NYBD tested negative for antibodies to HTLV types 1 and 2 and HTLV Tax. HTLV tax sequences were not detected in the NYBD lymphocytes. These data demonstrate the lack of HTLV-1 tax in this group of NYBD at low risk for HTLV infection...
  67. ncbi [Absence of HTLV-I/II virus circulation in blood donors from the provinces of Santa Fe and Santiago del Estero]
    R Gastaldello
    Laboratorio de Virus Linfotrópicos Humanos, Instituto de Virologia, Facultad de Medicina, Universidad Nacional de Cordoba, Av Enfermera Gordillo Gomez s n, Ciudad Universitaria, 5016 Cordoba, Argentina
    Rev Argent Microbiol 34:107-9. 2002
    ..These results suggest that HTLV-I/II are not circulating in low risk populations in these provinces or that the prevalences of infection would be lower than that reported by blood banks in other provinces of Argentina...
  68. ncbi [The prevalence of serum IgG antibodies against HTLV viruses type I and II in sarcoidosis patients]
    Alicja Sieminska
    Katedry i Kliniki Chorób Płuc i Gruźlicy AM w Gdańsku
    Pneumonol Alergol Pol 70:52-7. 2002
    ..The values of OD ranged in group I from 0.061 to 0.384 and in group II from 0.047 to 0.213; thus, no positive results of the test were observed. The values of OD did not differ significantly in both groups (p = 0.59)...
  69. ncbi Strategies for diagnosis of HTLV-I and -II
    Rigmor Thorstensson
    Department of Immunology, Swedish Institute for Infectious Disease Control, Solna, Sweden
    Transfusion 42:780-91. 2002
    ..No gold standard exists for diagnosis of HTLV infection. The aim of thus study was to compare the accuracy of a combination of two sensitive ELISAs with Western blot (WB), a line immunoassay, and PCR for diagnosis of HTLV infection...
  70. pmc High prevalence of simian T-lymphotropic virus type L in wild ethiopian baboons
    Taichiro Takemura
    Institute for Virus Research, Kyoto University, Kyoto 606 8507, Japan
    J Virol 76:1642-8. 2002
    ..Further studies are required to know if STLV-L is spreading into human populations...
  71. ncbi Chimeric synthetic peptides from the envelope (gp46) and the transmembrane (gp21) glycoproteins for the detection of antibodies to human T-cell leukemia virus type II
    M Hernández Marin
    Department of Peptide Synthesis, Immunoassay Center, Havana, Cuba
    Biochem Biophys Res Commun 289:7-12. 2001
    ..Those results may be related to a higher peptide adsorption capacity to the solid surface and for epitope accessibility to the antibodies. This chimeric peptide would be very useful for HTLV-II diagnostic...
  72. ncbi Immunofluorescence assay reactivity patterns of serum samples presenting indeterminate Western blot results for antibodies to HIV-1 and HTLV-I/II in Cordoba, Argentina
    R Gastaldello
    Institute of Virology Dr J M Vanella, Faculty of Medical Science, National University of Cordoba, Cordoba, Argentina
    Rev Inst Med Trop Sao Paulo 43:277-82. 2001
    ..Finally, this study shows the potential usefulness of IFA in elucidating the status of HIV-1 and HTLV-I/II infection of individuals with indeterminate Wb profiles, thus enabling resolution of retrovirus infection status...
  73. ncbi Seroprevalence of specific viral infections in confiscated orangutans (Pongo pygmaeus)
    K S Warren
    Wanariset Orangutan Reintroduction Centre, East Kalimantan, Indonesia
    J Med Primatol 27:33-7. 1998
    ..The results confirm the importance of quarantine and the need for diagnostic differentiation of virus infections to determine if they are of human origin or unique orangutan viruses...
  74. ncbi HTLV-I in Northeast Brazil: differences for male and female injecting drug users
    I Dourado
    Instituto De Saude Coletiva, Salvador, Bahia, Brazil
    J Acquir Immune Defic Syndr Hum Retrovirol 19:426-9. 1998
    ..To investigate the seroprevalence of HTLV-I infection among male and female injecting drug users (IDUs)...
  75. ncbi Evidence among blood donors for a 30-year-old epidemic of human T lymphotropic virus type II infection in the United States
    E L Murphy
    Department of Laboratory Medicine, UCSF Box 0884, San Francisco, CA 94143, USA
    J Infect Dis 180:1777-83. 1999
    ..These data are consistent with a 30-year-old epidemic of HTLV-II in the United States due to injection drug use and secondary sexual transmission and with an apparent West Coast focus...
  76. ncbi A seroepidemiological survey of HTLV-I/II carriers in the Puna Jujeña
    J E Dipierri
    Instituto de Biologia de la Altura, Universidad Nacional de Jujuy, Argentina
    Medicina (B Aires) 59:717-20. 1999
    ..This distribution is probably linked both to a history of prehistoric human dispersal in the Andes and to high mother- to-child transmission of the virus under close conditions of each group...
  77. ncbi [Screening of donor blood for viral markers. Anti-HIV, HBsAg and anti-HTLV-I/II in Denmark 1990-1999]
    E Dickmeiss
    H:S Rigshospitalet, klinisk immunologisk afdeling, og epidemiologisk afdeling, Statens Serum Institut,
    Ugeskr Laeger 163:2623-8. 2001
    ..The frequency of HTLV-I infection among candidate donors was 1 in 50,000 and that of HTLV-II infection 1 in 100,000. No seroconverters have been found...
  78. ncbi [HTLV-I/II seroprevalence and risk factors associated with infection in a blood donor population in Córdoba, Argentina]
    S Gallego
    Instituto de Virologia Dr J M Vanella, Facultad de Ciencias Medicas, Universidad Nacional de Cordoba, Argentina
    Rev Argent Microbiol 33:182-6. 2001
    ....
  79. ncbi Constitutive production of interleukin-6 and tumor necrosis factor-alpha from spontaneously proliferating T cells in patients with human T-cell lymphotropic virus type-I/II
    R B Lal
    Retrovirus Diseases Branch, Centers for Disease Control, Atlanta, GA 30333
    Blood 78:571-4. 1991
    ..None of the other cytokines (IL-1 beta, IL-2, IL-3, IL-4, and IFN-tau) were detectable in any of the culture. These data suggest that release of IL-6 and TNF-alpha may regulate lymphocyte proliferation in HTLV-I/II-infected individuals...
  80. ncbi Evaluation of a combined lysate/recombinant antigen anti-HTLV-I/II ELISA in high and low endemic areas of HTLV-I/II infection
    H Vrielink
    Red Cross Blood Bank Amsterdam, The Netherlands
    Transfus Med 5:135-7. 1995
    ..In Ethiopia 55% of the HTLV-I/II WB-positive individuals were exclusively HTLV-II positive, whereas in Curaçao no HTLV-II infections were found...
  81. ncbi Sensitivity of two enzyme-linked immunosorbent assay tests in relation to western blot in detecting human T-cell lymphotropic virus types I and II infection among HIV-1 infected patients from São Paulo, Brazil
    A Caterino de Araujo
    Instituto Adolfo Lutz, , Brazil
    Diagn Microbiol Infect Dis 30:173-82. 1998
    ....