Genomes and Genes
pituitary hormone releasing hormones
Summary: Hormones released by one structure (e.g., the hypothalamus or the thyroid gland) that effect the secretion of hormones from the pituitary gland.
Publications121 found, 100 shown here
- Chronology of advances in neuroendocrine immunomodulationSamuel M McCann
Centro de Estudios Farmacologicos y Botanicos, Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires, Argentina
Ann N Y Acad Sci 1088:1-11. 2006..All of these transmitters are controlled by neuronal transmitters. We anticipate further rapid progress and clinical application of these transmitters and the discovery of new ones...
- Synthesis of the porcine LH- and FSH-releasing hormone by the solid-phase methodH Matsuo
Biochem Biophys Res Commun 45:822-7. 1971
- Transgenic studies on the regulation of the anterior pituitary gland function by the hypothalamusSara Wells
Molecular Neuroendocrinology Research Group, University Research Centre for Neuroendocrinology, University of Bristol, Bristol Royal Infirmary, UK
Front Neuroendocrinol 24:11-26. 2003....
- Structure of the porcine LH- and FSH-releasing hormone. II. Confirmation of the proposed structure by conventional sequential analysesY Baba
Biochem Biophys Res Commun 44:459-63. 1971
- On the tryptophan residue in porcine LH and FSH-releasing hormoneY Baba
Biochem Biophys Res Commun 45:483-7. 1971
- Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphinW Vale
Science 213:1394-7. 1981
- Effect of active and passive immunization of male and female rats with a recombinantly expressed bonnet monkey pituitary GnRH receptor fragmentSumana Santra
Department of Biochemistry, Indian Institute of Science, Bangalore
Am J Reprod Immunol 48:117-25. 2002..However, in the female rats, active immunization with the receptor fragment did not have any effect on the gonadal steroid levels but had a selective effect on the uterine morphology...
- Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LRF) (LH-hypothalamus-LRF-gas chromatography-mass spectrometry-decapeptide-Edman degradation)R Burgus
Proc Natl Acad Sci U S A 69:278-82. 1972..The synthetic decapeptide possesses the same biological activities as the native ovine LRF. The amino-acid sequence of ovine LRF is identical to that already published for porcine LRF...
- An improved computational method to assess pituitary responsiveness to secretagogue stimuliAlessandro Sartorio
Laboratorio Sperimentale di Ricerche Endocrinologiche, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Eur J Endocrinol 147:323-32. 2002..The objective was to introduce and validate an easy-to-compute responsiveness index, robust in the face of measurement errors and interindividual variability of kinetics parameters...
- Brain grafts reverse hypogonadism of gonadotropin releasing hormone deficiencyD T Krieger
Nature 298:468-71. 1982..The testes were enlarged and had descended into the scrotum. Evidence of full spermatogenesis and interstitial cell development was present in testicular sections. No such effects were seen with transplants of cortical tissue...
- Development of radioimmunoassay for bullfrog thyroid-stimulating hormone (TSH): effects of hypothalamic releasing hormones on the release of TSH from the pituitary in vitroReiko Okada
Department of Biology, School of Education, Waseda University, Nishiwaseda 1 6 1, Shinjuku ku, 169 8050, Tokyo, Japan
Gen Comp Endocrinol 135:42-50. 2004....
- Phenotypic characterization of multi-functional somatotropes, mammotropes and gonadotropes of the mouse anterior pituitaryCarlos Villalobos
Departamento de Fisiologia y Bioquimica, Facultad de Medicina, Instituto de Biología y Genética Molecular IBGM, Universidad de Valladolid and Consejo Superior de Investigaciones Cientificas CSIC, Ramón y Cajal 7, 47005 Valladolid, Spain
Pflugers Arch 449:257-64. 2004....
- Stimulatory effects of gonadotropin-releasing hormone and dopamine on growth hormone release and growth hormone mRNA expression in Epinephelus coioidesXue Qin Ran
Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, Zhongshan University, Guangzhou 510275, China
Sheng Li Xue Bao 56:644-50. 2004..These results demonstrate that both GnRH and DA directly stimulate GH release and GH mRNA expression at the pituitary level, the actions of GnRH are more potent than that of DA in orange-spotted grouper...
- Luteinizing hormone stimulates the formation of inositol trisphosphate and cyclic AMP in rat granulosa cells. Evidence for phospholipase C generated second messengers in the action of luteinizing hormoneJ S Davis
Biochem J 238:597-604. 1986..Our findings suggest that two messenger systems exist to mediate the action of LH in granulosa cells...
- Regulative actions of the Chinese drugs for tonifying the kidney on gene expression of the hypothalamic GnRH, pituitary FSH, LH and osteoblastic BGPDepei Cai
Pediatric Hospital Affiliated to Shanghai Medical University, Shanghai 200032, China
J Tradit Chin Med 25:58-61. 2005....
- Effects of oxytocin alone and in combination with selected hypothalamic hormones on ACTH, beta-endorphin, LH and PRL secretion by anterior pituitary cells of cyclic pigsGenowefa Kotwica
Department of Animal Physiology, University of Warmia and Mazury in Olsztyn, 10 719 Olsztyn Kortowo, ul Oczapowskiego 1A, Poland
Reprod Biol 6:115-31. 2006..Moreover, interaction between OT and CRH in affecting beta-endorphin secretion was shown. These results suggest that OT may be transiently involved in the modulation of anterior pituitary hormone secretion in cyclic pigs...
- Regulation of hypophysiotrophic corticotrophin-releasing hormone- and thyrotrophin-releasing hormone-synthesising neurones by brainstem catecholaminergic neuronesG Wittmann
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
J Neuroendocrinol 20:952-60. 2008..The present review summarises the data obtained in recent years concerning the functional significance of the catecholaminergic innervation of hypophysiotrophic CRH and TRH neurones in rats...
- Endocrine function is not impaired in patients with a continuous MicroMed-DeBakey axial flow pumpGeorg M Wieselthaler
Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
J Thorac Cardiovasc Surg 133:2-6. 2007..Patients with implanted MicroMed-DeBakey axial pumps show nonphysiologic low-pulsatile blood flow profiles, and therefore it appeared to be of interest to evaluate their possible effect on the endocrine system...
- Emerging functions for tuberoinfundibular peptide of 39 residuesTed B Usdin
Laboratory of Genetics, National Institute of Mental Health, National Institutes of Health, Building 36 Room 3D06, 36 Convent Drive, Bethesda, MD 20892 4094, USA
Trends Endocrinol Metab 14:14-9. 2003..Injection of TIP39, and sequestration of endogenous TIP39 by intrathecal injection of an antibody to TIP39, have provided evidence that it is involved in some aspects of pain sensitivity. Thus, TIP39 might be a new neuromodulator...
- The rat gonadotropin-releasing hormone: SH locus: structure and hypothalamic expressionC T Bond
Department of Cell Biology, Oregon Health Sciences University, Portland 97201
Mol Endocrinol 3:1257-62. 1989..The SH gene contains at least two distinct promoters, from which two populations of transcripts are derived containing unique 5'-sequences spliced to a common 3'-region...
- GnRH stimulates expression of PACAP in the pituitary gonadotropes via both the PKA and PKC signaling systemsConstance M Grafer
Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9032, USA
Mol Endocrinol 23:1022-32. 2009..Because both PACAP and GnRH regulate gonadotropin biosynthesis and secretion, these results provide important insight into the critical fine tuning of gonadotrope function and, thereby, the maintenance of normal reproductive function...
- Cloning of a cDNA encoding an ectoenzyme that degrades thyrotropin-releasing hormoneB Schauder
Max Planck Institut fur Experimentelle Endokrinologie, Hannover, Federal Republic of Germany
Proc Natl Acad Sci U S A 91:9534-8. 1994..Finally, transient transfection of COS-7 cells with this cDNA led to the expression of an active ectopeptidase that displayed the characteristics of the TRH-degrading ectoenzyme...
- Pyroglutamyl peptidase: an overview of the three known enzymatic formsP M Cummins
School of Biological Sciences, Dublin City University, Dublin, Ireland
Biochim Biophys Acta 1429:1-17. 1998..Pyroglutamyl peptidase activities isolated and characterized from bacterial sources are also reviewed and compared with their mammalian counterparts...
- Neuroendocrine control of food intakeElena Valassi
Chair of Endocrinology, University of Milan, Ospedale San Luca IRCCS, Istituto Auxologico Italiano, Via Spagnoletto 3, 20149 Milan, Italy
Nutr Metab Cardiovasc Dis 18:158-68. 2008..In conclusion, the present work reviews the most recent insights into the complex and redundant molecular mechanisms regulating food intake, focusing on the most encouraging perspectives for the treatment of obesity...
- Excess corticotropin releasing hormone-binding protein in the hypothalamic-pituitary-adrenal axis in transgenic miceH L Burrows
Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, Michigan 48109, USA
J Clin Invest 101:1439-47. 1998..Alterations in CRH and AVP in response to elevated pituitary CRH-BP clearly demonstrate that regulation of CRH-BP is important in the function of the HPA axis...
- Mating and pregnancy can occur in genetically hypogonadal mice with preoptic area brain graftsM J Gibson
Science 225:949-51. 1984..Immunocytochemistry revealed GnRH-containing neurons in the grafts and GnRH-containing processes extending to the lateral median eminence of the host brains...
- Usefulness of the free alpha-subunit to diagnose hypogonadotropic hypogonadismAlberto Scofano Mainieri
Adolescent Medical Service and Endocrinology Service, , Brazil
Clin Endocrinol (Oxf) 59:307-13. 2003..This distinction allows early investigation and treatment of patients with hypogonadotropic hypogonadism and reassurance for those with constitutional delay of growth and puberty...
- The parathyroid hormone 2 (PTH2) receptorT B Usdin
Laboratory of Genetics, National Institute of Mental Health, Building 36 Room 3D06, 36 Convent Drive, Bethesda, Maryland 20892 4094, USA
Receptors Channels 8:211-8. 2002..Functional hypotheses based on the receptor's distribution are being tested. Recent data support involvement in hypothalamic releasing-factor secretion and pain...
- Leukotriene C4-induced release of LHRH into the hypophyseal portal blood and of LH into the peripheral bloodM Saadi
Institut Pasteur, URIA, INSERM U 207, Paris, France
Life Sci 46:1857-65. 1990..Then the action of LTC4 on LH release in vivo is quite different from the indirect action of PGE2...
- Thymocytes express a mRNA that is identical to hypothalamic luteinizing hormone-releasing hormone mRNAC C Maier
Department of Physiology and Biophysics, University of Alamaba, Birmingham 35294 0005
Cell Mol Neurobiol 12:447-54. 1992..4. This is the first report showing conclusively that cell of the immune system transcribe the authentic mRNA for a hypothalamic releasing factor, LHRH...
- Fishy tales of prolactin-releasing peptideTatsuya Sakamoto
Ushimado Marine Laboratory, Okayama University, Okayama 701 4303, Japan
Int Rev Cytol 225:91-130. 2003..Moreover, it plays a direct role in hypertension and retinal information processing. It is the purpose of this review to provide a comprehensive survey of our current knowledge of PrRP and to provide a comparative point of view...
- Mass spectrometry, high performance liquid chromatography, and brain peptidesD M Desiderio
Department of Neurology, Charles B Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee, Memphis 38163, USA
Biopolymers 40:257-64. 1996....
- Effects of progesterone and weaning on LH and FSH responses to naloxone in postpartum beef cowsJ C Cross
Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada
Domest Anim Endocrinol 4:111-22. 1987..We conclude that LH release in the early postpartum cow is partially regulated by endogenous opioid peptides. We were unable to detect any effects on FSH secretion nor on pituitary sensitivity to exogenous GnRH...
- Pituitary and Leydig cell function in boars actively immunized against gonadotrophin-releasing hormoneC A Awoniyi
Department of Physiology, School of Medicine, Southern Illinois University, Carbondale, IL 62901
J Reprod Fertil 84:295-302. 1988..05) in GnRH-immunized boars. These results indicate that active immunization against GnRH impairs pituitary and Leydig cell functions in boars...
- Culture of functionally active human pituitary cells: investigation of gonadotropin regulationP J Wormald
Department of Chemical Pathology, University of Cape Town Medical School, Observatory, Republic of South Africa
J Clin Endocrinol Metab 66:1272-7. 1988..We conclude that functionally active cells can be cultured from human pituitaries obtained postmortem and that the mechanism of GnRH action and the relative potencies of GnRH analogs closely parallel those in the rat...
- Ovulation inductionJ L Kennedy
Department of Obstetrics and Gynecology, University of Maryland School of Medicine and Hospital, Baltimore
Obstet Gynecol Clin North Am 14:831-64. 1987..Methods to restore ovulation in patients with polycystic ovarian disease refractory to clomiphene citrate is the quest of future investigations...
- Plasma gonadotropin-releasing hormone profiles after intravenous and subcutaneous bolus injection in thin and obese womenR Lyles
Reproductive Research Laboratory, St Luke s Episcopal Hospital, Houston, Texas
Obstet Gynecol 71:44-8. 1988..These findings may be relevant to therapeutic failures observed in obese subjects using the subcutaneous route...
- [Clinical value of the gonadotropic hormone releasing hormone (GHRH) test in the diagnosis of growth deficiency]R Hümmelink
Pädiatrische Endokrinologie, Universitäts Kinderklinik Kiel
Monatsschr Kinderheilkd 136:618-21. 1988..05) in the group of children with constitutional short stature than in GH deficient patients, but there were overlaps in this group with normal volunteers and other groups of patients with growth failure...
- Pre- and postsynaptic actions of GABA on the release of hypothalamic gonadotropin-releasing hormone (GnRH)K E Nikolarakis
Department of Neuropharmacology, , Planegg Martinsried
Brain Res Bull 21:677-83. 1988..Lastly, all the effects of GABA upon GnRH release appear to be mediated through GABAA receptors...
- Indomethacin inhibits hCG and GnRH agonist-induced secretion of plasminogen activator by granulosa and theca interstitial cells of hypophysectomized ratsY X Liu
Laboratory of Reproductive Biology, Institute of Zoology, Academia Sinica, Beijing
Sci Sin B 31:807-17. 1988..The results indicate that indomethacin can only suppress hCG- and GnRH agonist-induced PA secretion, but not suppress the ovarian content of these enzymes...
- Induction of spermatogenesis and fertility in hypogonadotropic azoospermic men by intravenous pulsatile gonadotropin-releasing hormone (GnRH)Z Blumenfeld
Department of Obstetrics and Gynecology A, Rambam Medical Center, Haifa, Israel
Gynecol Endocrinol 2:151-64. 1988..The second pregnancy ended in spontaneous delivery of a healthy female. We conclude that i.v. pulsatile, intermittent GnRH administration is a safe, efficient and highly successful means of treating azoospermic men with HH...
- Effect of hysterectomy on the short life-cycle corpus luteum produced after GnRH-induced ovulation in the anoestrous eweJ A Southee
A F R C Research Group on Hormones and Farm Animal Reproduction, University of Nottingham, Faculty of Agricultural Science, Leics, U K
J Reprod Fertil 84:149-55. 1988....
- Effects of estrogen on hypothalamic gonadotropin-releasing hormone release in castrated male rhesus macaquesK Y Pau
Reproductive Biology and Behavior, Oregon Regional Primate Research Center, Beaverton 97006
Brain Res 459:70-5. 1988..In contrast, estrogen enhanced GnRH level and pulse amplitude, but not pulse frequency, several hours before mean peripheral plasma LH increased from suppressed values (n = 4).(ABSTRACT TRUNCATED AT 250 WORDS)..
- Neuronal systems immunoreactive with antiserum to lamprey gonadotropin-releasing hormone in the brain of Petromyzon marinusJ C King
Department of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston, Massachusetts 02111
Cell Tissue Res 253:1-8. 1988..No reaction product was detected in sections incubated with an antiserum to the interior amino acid sequences of mammalian LHRH. This finding supports the structure reported for lamprey GnRH by Sherwood et al. (1986)...
- Normal neonatal surge of gonadotrophins and sex steroids in infants of men with isolated hypogonadotrophic hypogonadismS R Rose
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD
Clin Endocrinol (Oxf) 29:577-82. 1988....
- Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputsEduardo A Nillni
Division of Endocrinology, Department of Medicine, The Warren Alpert Medical School of Brown University Rhode Island Hospital, RI, USA
Front Neuroendocrinol 31:134-56. 2010....
- The endocrinology of varicocelesR W Hudson
Faculty of Medicine, Queen s University, Kingston, Ontario, Canada
Fertil Steril 49:199-208. 1988..As our knowledge of the paracrine system within the testis increases, so should our understanding of the mechanisms involved in the association of varicoceles and infertility...
- Intact adrenocorticotropic hormone secretion but impaired cortisol response in patients with active rheumatoid arthritis. Effect of glucocorticoidsB Gudbjornsson
Department of Medicine, Uppsala University Hospital, Sweden
J Rheumatol 23:596-602. 1996..To study the hypothalamic-pituitary-adrenal axis in rheumatoid arthritis (RA) and the influence of glucocorticoid treatment...
- Effects of thyrotropin-releasing hormone on the sleep EEG and nocturnal hormone secretion in male volunteersU Hemmeter
Max Planck Institute of Psychiatry, Munich, Germany
Neuropsychobiology 38:25-31. 1998..On the basis of these findings, we surmise that TRH may contribute to the disturbed sleep continuity seen in depressed patients, probably acting as a cofactor of CRH in a synergistic manner...
- The hypothalamic mechanisms of the hypophysiotropic action of ghrelinAlison M Wren
Endocrine Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK
Neuroendocrinology 76:316-24. 2002..These data suggest that the mechanisms of GH and ACTH regulation by ghrelin may include hypothalamic release of GHRH, CRH, AVP and NPY...
- Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuitP J Larsen
Rheoscience, Rødovre, Denmark
J Neuroendocrinol 15:219-26. 2003..The current study provides further evidence that CART is a neuroendocrine-releasing factor with a possible impact on anterior pituitary function during states of haemodynamic stress...
- Suppression of serum immunoreactive human epidermal growth factor by acute increase in prolactin in womenC F Chen
Department of Obstetrics and Gynecology, Osaka University Medical School, Japan
Endocrinol Jpn 36:203-9. 1989..These results suggest that an acute increase of serum PRL in normoprolactinemic women, but not in hyperprolactinemic patients, suppresses serum EGF...
- In vivo correlation between c-Fos expression and corticotroph stimulation by adrenocorticotrophic hormone secretagogues in rat anterior pituitary glandShu Takigami
Department of Anatomy, Jichi Medical University School of Medicine, Shimotsuke shi, Tochigi, Japan
Cell Tissue Res 331:589-94. 2008..Although the mechanism underlying the different responses to CRH is not apparent, c-Fos is probably a useful immunohistochemical marker for corticotrophs stimulated by ACTH secretagogues...
- Combined pituitary stimulation test: interactions of hypothalamic releasing hormones in manR W Holl
Department of Pediatrics, University of Ulm, West Germany
J Endocrinol Invest 11:219-23. 1988..05). This exaggerated TSH-response to TRH was demonstrated to be entirely due to simultaneous administration of GRF, whereas CRF and LHRH in combination with TRH had no additional effect on TSH release.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Gonadal regulation of corticotropin-releasing factor immunoreactivity in hypothalamusD A Haas
Department of Medicine, University of Toronto, Ontario, Canada
Brain Res Bull 20:361-7. 1988..Chronic estradiol treatment decreased hypothalamic CRF-ir, by a non-pituitary mechanism. These data show significant effects of the gonadal axis in the regulation of CRF in the hypothalamus in both sexes...
- Pulsatile infusion of gonadotrophin releasing hormone (GnRH): investigative and therapeutic applicationsI A Sutherland
Department of Obstetrics and Gynaecology, St Mary s Hospital Medical School, London, UK
J Biomed Eng 10:110-2. 1988..There was only one multiple pregnancy (twins)...
- The efficacy of every-other-day administration of gonadotropin-releasing hormone in women with hypothalamic amenorrhea: gonadotropin-releasing hormone treatment can induce clomiphene responsivenessF Kotsuji
Department of Obstetrics and Gynecology, Fukui Medical School, Japan
Obstet Gynecol 71:615-21. 1988..In normogonadotropic women, gonadotropin-releasing hormone treatment may be useful in those who have been amenorrheic for less than a year...
- Clinical applications of gonadotrophin-releasing hormone and its analoguesG Bartfai
Department of Obstetrics and Gynecology, University Medical School of Szeged, Hungary
Hum Reprod 3:51-7. 1988..They are more valuable in the treatment of endometriosis, hormone-dependent cancers, the polycystic ovary and for the induction of ovulation for in-vitro fertilization...
- Pulsatile administration of gonadotrophin-releasing hormone stimulates, in oestrogen-treated anaesthetized ovariectomized ewes, a surge release of LH qualitatively and quantitatively different from that induced by oestradiol in conscious ovariectomized ewP J Wright
Department of Veterinary Clinical Sciences, University of Melbourne, Werribee, Victoria, Australia
J Endocrinol 116:143-8. 1988....
- Effect of injection of gonadotrophin-releasing hormone on testicular steroidogenesis in the hypogonadal (hpg) mouseJ W Sheffield
Department of Veterinary Basic Sciences, Royal Veterinary College, London, UK
J Reprod Fertil 86:609-17. 1989..These results show that GnRH treatment of hpg mice will induce testicular steroidogenesis.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Metabolic regulation of the growth hormone independent insulin-like growth factor binding protein in human plasmaS I Yeoh
Department of Endocrinology, Royal Prince Alfred Hospital, Camperdown, Australia
Acta Endocrinol (Copenh) 119:465-73. 1988..We conclude that BP-28 levels in adults are metabolically regulated, and postulate a role for this protein in the maintenance of glucose homeostasis...
- Acute dexamethasone suppression of ACTH secretion stimulated by human corticotrophin releasing hormone, AVP and hypoglycaemiaJ Hohnloser
Medizinishce Klinik Innenstadt, University of Munich, FR Germany
Clin Endocrinol (Oxf) 31:175-84. 1989..The GRH-stimulated GH secretion (3596 +/- 820 (mU/l) min) was not suppressed by prior intravenous treatment with dexamethasone (2916 +/- 504 (mU/l) min, NS)...
- Progestins modulate the action of estrogen on gonadotropin-releasing hormone, luteinizing hormone and prolactin in the ratA R Genazzani
Department of Obstetrics and Gynecology, University of Modena, Italy
Gynecol Obstet Invest 29:197-202. 1990..These results showed that progesterone and progestins have a marked effect on hypothalamic and pituitary hormone secretion and that they modulate estrogen-induced effects...
- Simultaneous effect of gonadotropin-releasing hormone (GnRH) on the expression of two gonadotropin beta genes by passive immunization to GnRHY Kato
Hormone Assay Center, Gunma University, Japan
Mol Cell Endocrinol 62:135-9. 1989..0-fold for alpha, 1.2-fold for LH beta and 1.1-fold for FSH beta relative to the respective control values. These results showed that the two gonadotropin beta genes respond more rapidly to GnRH action that the common alpha gene...
- Evaluation of hypothalamic-pituitary function in a combination of tests with four hypothalamic releasing hormones and L-dopa in normal subjects and in patients with hypothalamic and/or pituitary disordersH Bando
First Department of Internal Medicine, School of Medicine, University of Tokushima, Japan
Endocrinol Jpn 36:705-20. 1989....
- Differential actions of dopamine receptor subtypes on gonadotropin and growth hormone release in vitro in goldfishJ P Chang
Department of Zoology, University of Alberta, Edmonton, Canada
Neuroendocrinology 51:664-74. 1990..abstract truncated at 400 words)..
- Studies on the subcellular mechanisms mediating the negative estradiol effect on GnRH-induced LH-release by rat pituitary cells in cultureG Emons
, , FRG
Acta Endocrinol (Copenh) 121:350-60. 1989..abstract truncated at 400 words)..
- Effects of thyrotropin-releasing hormone and gonadotropin-releasing hormone on inositol phospholipid turnover in endocrinologically inactive pituitary adenomas and prolactinomasA Levy
Department of Medicine, Charing Cross and Westminster Hospital Medical School, London, United Kingdom
J Clin Endocrinol Metab 69:122-6. 1989..The phosphatidyl inositol-linked receptor status of these tumors differs from that of prolactinomas. These receptors may offer a possible target for therapeutic intervention in endocrinologically inactive adenomas...
- Effects of gonadotropin-releasing hormone and human chorionic gonadotropin on pregnancy rate in dairy cattleG S Lewis
Reproduction Laboratory, US Department of Agriculture, Beltsville, MD 20705
J Dairy Sci 73:66-72. 1990..This study does not support the general use of gonadotropin-releasing hormone at AI or human chorionic gonadotropin 15 d after AI as methods for enhancing pregnancy rates of dairy cattle...
- The effect of HCG supplementation after combined GnRH agonist/HMG treatment in an IVF programmeJ Belaisch Allart
Department of Obstetrics and Gynaecology, , Clamart, France
Hum Reprod 5:163-6. 1990..7 versus 9.3). This is the first truly objective (randomized) study demonstrating the beneficial effect of supporting the luteal phase in an IVF programme...
- Ultrastructural differences between smooth and thorny gonadotropin-releasing hormone neuronsJ W Witkin
Columbia University College of Physicians and Surgeons, Department of Anatomy and Cell Biology, New York, NY 10032
Neuroscience 34:777-83. 1990..abstract truncated at 250 words)..
- Gonadotropin-releasing hormone inhibition of LH stimulated progesterone secretion by porcine granulosa cells in vitroF Ledwitz Rigby
Department of Biological Sciences, Northern Illinois University, DeKalb 60115
Domest Anim Endocrinol 7:265-72. 1990..GnRHa did not alter the DNA content of the cultures in up to 6 day incubations or the number of viable cells attached to the wells in up to 3 day incubations.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Gonadotrophin response to releasing hormone in post-menopausal patients with ovarian tumoursD Mango
Department of Obstetrics and Gynaecology, Catholic University, Rome, Italy
Maturitas 11:129-36. 1989..001). These data are consistent with an increased LH response to GnRH in post-menopausal patients with ovarian tumours. The augmented LH release may be related to increased steroid plasma levels...
- Combined anterior pituitary function test using CRH, GRH, LH-RH, TRH and vasopressin in patients with non-functioning pituitary tumorsK Hashimoto
Third Department of Internal Medicine, Okayama University Medical School, Japan
Acta Med Okayama 44:141-7. 1990..No subjects experienced any serious adverse effects related to the testing. These results suggest that combined testing with hypothalamic hormones is a convenient and useful method for evaluating pituitary function...
- Effects of a gonadotropin-releasing hormone agonist on sexual behavior in male rhesus monkeys (Macaca mulatta)J J Turner
Division of Neurobiology, Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia
Fertil Steril 53:578-80. 1990..The normal, seasonal cessation of sexual behavior in male rhesus monkeys may result from changes in behavioral sensitivity to circulating androgens...
- [In situ biosynthesis of LH in cultured anterior pituitary cells: effects of GnRH]R Counis
Laboratorie des Hormones Polypeptidiques, CNRS, Gif sur Yvette, France
Pathol Biol (Paris) 35:1147-51. 1987..This stimulatory effect of GnRH was more pronounced for the highly glycosylated forms of alpha (23 and 25 K) compared to the 16 and 21 K forms.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Circulating inhibin alpha concentrations in infant, prepubertal, and adult male rhesus monkeys (Macaca mulatta) and in juvenile males during premature initiation of puberty with pulsatile gonadotropin-releasing hormone treatmentS A Abeyawardene
Department of Physiology, University of Pittsburgh School of Medicine, Pennsylvania 15261
Endocrinology 125:250-6. 1989..The results also fail to provide evidence for the view that changes in circulating inhibin concentrations are robustly related, in an inve..
- Detection of testicular endocrine abnormalities and their correlation with serum antisperm antibodies in men following vasectomyH Fisch
Department of Urology, Einstein Montefiore Medical Center, Bronx, New York
J Urol 141:1129-32. 1989..In addition, serum antisperm antibodies are most likely to be present in men who demonstrate normal seminiferous tubular activity after vasectomy...
- Estradiol-concentrating cells in the brains of hypogonadal female mice and in their intraventricular preoptic area implantsM J Gibson
Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029
Exp Neurol 105:127-34. 1989..No specific relationship between GnRH cells and estradiol-concentrating cells was evident within the grafts, nor was there any indication of identity of estrogen-concentrating cells with GnRH cells...
- Relationship of plasma beta-carotene and vitamin A to luteal function in postpartum cattleR L Graves Hoagland
Department of Animal Science, University of Connecticut, Storrs 06268
J Dairy Sci 72:1854-8. 1989..The regression coefficients were positive for beta-carotene and negative for vitamin A in all cases. In conclusion, luteal function in the postpartum cow appears to be related to plasma concentrations of beta-carotene and vitamin A...
- Plasma prolactin response to gonadotropin-releasing hormone during benzodiazepine treatmentL De Marinis
Institute of Endocrinology, The Catholic University School of Medicine, Rome, Italy
Psychoneuroendocrinology 13:325-31. 1988..5%) and at 60-90 min in the postmenopausal subjects (mean % increase: 110.6 +/- 34.7%). A saline infusion, performed on a separate day during benzodiazepine treatment as a control, did not influence PRL...
- Estradiol stimulates preoptic area-anterior hypothalamic proGnRH-GAP gene expression in ovariectomized ratsJ L Roberts
Fishberg Research Center for Neurobiology, Mt Sinai School of Medicine, New York, NY 10029
Brain Res Mol Brain Res 6:127-34. 1989..These data support the view that estradiol stimulates the levels of both proGnRH-GAP mRNA and its primary translation product in the POA-AH region of the OVX rat...
- Gonadal steroid modulation of signal transduction and luteinizing hormone release in cultured chicken pituitary cellsJ A King
Department of Chemical Pathology, University of Cape Town Medical School, South Africa
Endocrinology 124:1830-40. 1989....
- A comparison of the actions of stimulatory follicular fluid and gonadotropin-releasing hormone analogs on progesterone secretion by porcine granulosa cellsF Ledwitz Rigby
Department of Biological Sciences, Northern Illinois University, DeKalb 60115
Biol Reprod 41:604-9. 1989..Alternatively, the stimulatory follicular fluid molecule may not resemble GnRH but may act via a mechanism that is opposed by GnRH...
- [Male hypogonadism in children and adolescents: diagnostic assessment and therapy indications]F Braggion
Istituto Scientifico H San Raffaele, , Italia
Pediatr Med Chir 11:577-82. 1989..Standardized and widely accepted therapies for specific forms of hypogonadism are briefly exposed. Three cases of hypogonadotropic hypogonadism are reported...
- Utility of free alpha-subunit as an alternative neuroendocrine marker of gonadotropin-releasing hormone (GnRH) stimulation of the gonadotroph in the human: evidence from normal and GnRH-deficient menR W Whitcomb
Department of Medicine, Massachusetts General Hospital, Boston 02114
J Clin Endocrinol Metab 70:1654-61. 1990....
- The response of cultured gonadotrophs to inhibin: the role of calcium mobilizationW G Simpson
Department of Anatomy, University of Kentucky College of Medicine, Lexington 40536
Endocr Res 13:267-84. 1987..Further investigation is warranted to assess a possible action of inhibin which is antagonistic to that of calcium in the transduction of GnRH stimulation into FSH release by the pituitary gonadotroph...
- The effects of chronic intermittent stress on basal and acute stress levels of TSH and GH, and their response to hypothalamic regulatory factors in the ratA Armario
, , Spain
Psychoneuroendocrinology 12:399-406. 1987..These data indicate that this type of chronic stress induced significant changes in basal and acute stress levels of GH and TSH in the rat...
- Opioid control of luteinizing hormone secretion in humansA R Genazzani
Department of Obstetrics and Gynecology, University of Modena, Italy
J Steroid Biochem 33:751-5. 1989..The clinical implications of EOP in reproductive medicine appear to be promising...
- Ultrasound monitoring of testis and prostate maturation in hypogonadotropic hypogonadic males during gonadotropin-releasing hormone treatmentD Canale
Postgraduate School of Andrology, University of Pisa Medical School, Italy
Fertil Steril 53:537-40. 1990..The ultrasound monitoring of the modifications of testis and prostate volume may represent a biological assay of the effects of GnRH treatment and offer additional data on the response of target organs to the hormonal treatment...
- Efficacy of intermittent or continuous administration of GnRH in inducing ovulation in early and late seasonal anoestrus in the PÃ¨re David's deer hind (Elaphurus davidianus)B J McLeod
AFRC Institute for Grassland and Animal Production, Hurley, Maidenhead, Berks, UK
J Reprod Fertil 91:229-38. 1991..However, more animals ovulate in response to this treatment in late than in early anoestrus (75% compared with 23%)...
- Mechanism of action of GnRH: the participation of calcium mobilization and activation of protein kinase C in gonadotropin secretionS S Stojilkovic
Endocrinology and Reproduction Research Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892
J Steroid Biochem 33:693-703. 1989....
- Pregnancy following administration of GNRH by means of portable pump: hormonal evaluation before and during therapyA Oliva
Istituto di Ginecologia,
Acta Eur Fertil 20:71-5. 1989..Some considerations about the results were suggested...
- Endocrine function in multiple sclerosisP Klapps
Neurology Clinic, Steglitz Clinic, Free University of Berlin, Germany
Acta Neurol Scand 85:353-7. 1992..However, the poststimulatory secretion of cortisol, growth hormone or thyroid-stimulating hormone was impaired in 7/31 patients, suggesting a possible preclinical endocrine insufficiency in these patients...
- Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapourE M Erfurth
Department of Internal Medicine, University Hospital, Lund, Sweden
Br J Ind Med 47:639-44. 1990..Increased plasma concentrations of selenium (Se) were associated with increased basal serum concentrations of TSH, decreased concentrations of basal serum cortisol, and decreased release of FSH...
- The influence of psychotropic drugs and releasing hormones on anterior pituitary hormone secretion in healthy subjects and depressed patientsG Laakmann
Psychiatrische Klinik, , FRG
Pharmacopsychiatry 23:18-26. 1990..The blunted growth hormone response in endogenous depression could be explained by inhibitory influences such as increased somatomedin-C concentrations or a hyperactivity of central beta-adrenergic-receptors...
- [Pulsatile administration of gonadotropin releasing hormone in the female. Diagnostic and therapeutic indications]J Bringer
Service d endocrinologie, , Montpellier
Presse Med 19:1276-81. 1990..However such a combined therapy is time-consuming and only permits to attempt 3 to 4 stimulated cycles during a year. Therefore the successful preliminary reports need to be confirmed by a further randomized study...
- The effect of acute ethanol exposure on clonidine-induced growth hormone release in male ratsH J Mauceri
Department of Biological Sciences, Northern Illinois University, DeKalb 60115
Alcohol 8:7-11. 1991..Anti-SRIF administered 30 minutes before ETOH or saline did not alter the response to GRH. These results suggest that ETOH reduces the GH responsiveness to alpha 2-GRH stimulation...
- Alpha-fetoprotein controls female fertility and prenatal development of the gonadotropin-releasing hormone pathway through an antiestrogenic actionChristelle De Mees
Universite Libre de Bruxelles, IBMM, Laboratoire de Biologie du Developpement, Rue Pr Jeener and Brachet 12, B 6041 Gosselies Charleroi, Belgium
Mol Cell Biol 26:2012-8. 2006..These results show that AFP protects the developing female brain from the adverse effects of prenatal estrogen exposure and clarify a long-running debate on the role of this fetal protein in brain sexual differentiation...
- Secretory patterns of LH and FSH during development and hypothalamic and hypophysial characteristics following development of steroid-induced ovarian follicular cysts in dairy cattleD L Cook
Department of Dairy Science, University of Missouri, Columbia 65211
J Reprod Fertil 91:19-28. 1991..2, respectively) groups during the follicular phase. There were no differences in the FSH, oestradiol-17 beta or progesterone characteristics in cows of any of the 3 groups during the follicular phase.(ABSTRACT TRUNCATED AT 400 WORDS)..
- Developmental changes in pituitary-gonadal function in free-ranging lions (Panthera leo leo) of the Serengeti Plains and Ngorongoro CraterJ L Brown
Department of Obstetrics and Gynecology, Uniformed Services University, Bethesda, MD 20814
J Reprod Fertil 91:29-40. 1991..The striking seminal/endocrine differences among pride (breeding) males of different ages raises questions about the impact of age on individual reproductive performance in this species...
- Corticotropin-Releasing Hormone-Binding ProteinAUDREY SEASHOLTZ; Fiscal Year: 2004....
- Pituitary PACAP gene regulation by hypothalamic, pituitary and gonadal factorsLisa Halvorson; Fiscal Year: 2007....
- Pituitary PACAP gene regulation by hypothalamic, pituitary and gonadal factorsLisa M Halvorson; Fiscal Year: 2010....
- PROTRH GENE TRANSCRIPTION AND BIOSYNTHESES BY LEPTINEDUARDO NILLNI; Fiscal Year: 2007..B) Since the melanocortin system represents the indirect pathway of action on TRH neurons, we will also determine whether alpha- MSH affects the biosynthesis, maturation and activity of PCI, PC2, proSAAS, 7B2 and CPE. ..
- ProTRH sorting to the regulated secretory pathwayEDUARDO NILLNI; Fiscal Year: 2006..The sorting of the proTRH N- and C-terminal fragments is routed to two different pathways. Aim 4. The tertiary structure of proTRH contributes to its processing by PC1 and PC2 and further sorting to the RSP. ..
- PROTRH GENE TRANSCRIPTION AND BIOSYNTHESIS BY LEPTINEDUARDO NILLNI; Fiscal Year: 2003..As a model system we will utilize our established primary cultures of hypothalamic neurons that express high levels of endogenous proTRH and leptin receptors. Some aspects will be corroborated with in vivo studies. ..
- Hypothalamic SIRT1 and Energy BalanceEduardo A Nillni; Fiscal Year: 2010..Therefore, this proposal provides a novel view assigned to Sirt1 as a cellular energy sensor regulating energy balance at the hypothalamic level. ..