poisoning

Summary

Summary: A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.

Top Publications

  1. Hawton K, Bergen H, Simkin S, Dodd S, Pocock P, Bernal W, et al. Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses. BMJ. 2013;346:f403 pubmed publisher
    To assess the long term effect of United Kingdom legislation introduced in September 1998 to restrict pack sizes of paracetamol on deaths from paracetamol poisoning and liver unit activity.
  2. Hanwella R, Senanayake S, de Silva V. Geographical variation in admissions due to poisoning in Sri Lanka: a time series analysis. Ceylon Med J. 2012;57:152-8 pubmed publisher
    To carry out time series analyses of hospital admissions for poisoning between 1995-2008 in all districts in Sri Lanka to identify trends and geographical variations in the substances used in poisoning.
  3. Churi S, Ramesh M, Bhakta K, Chris J. Prospective assessment of patterns, severity and clinical outcome of Indian poisoning incidents. Chem Pharm Bull (Tokyo). 2012;60:859-64 pubmed
    The objective of this study was to assess the patterns, severity and clinical outcome of poisoning incidents. A prospective assessment was conducted over a period of 1 year in tertiary-care teaching hospitals...
  4. Chen L, Huang G. Poisoning by toxic animals in China--18 autopsy case studies and a comprehensive literature review. Forensic Sci Int. 2013;232:e12-23 pubmed publisher
    ..Causes of death were grouped into 6 categories, including 1 case of tetrodotoxin poisoning, 1 case of gallbladder poisoning, 3 cases of snake venom toxicity, 4 cases of melittin toxicity, 4 cases of ..
  5. Ghannoum M, Nolin T, Goldfarb D, Roberts D, Mactier R, Mowry J, et al. Extracorporeal treatment for thallium poisoning: recommendations from the EXTRIP Workgroup. Clin J Am Soc Nephrol. 2012;7:1682-90 pubmed publisher
    The EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup was formed to provide recommendations on the use of extracorporeal treatment (ECTR) in poisoning...
  6. Rajapakse T, Griffiths K, Christensen H. Characteristics of non-fatal self-poisoning in Sri Lanka: a systematic review. BMC Public Health. 2013;13:331 pubmed publisher
    The rate of non-fatal self-poisoning in Sri Lanka has increased in recent years, with associated morbidity and economic cost to the country...
  7. Carter G, Clover K, Whyte I, Dawson A, D Este C. Postcards from the EDge: 5-year outcomes of a randomised controlled trial for hospital-treated self-poisoning. Br J Psychiatry. 2013;202:372-80 pubmed publisher
    Repetition of hospital-treated self-poisoning and admission to psychiatric hospital are both common in individuals who self-poison. To evaluate efficacy of postcard intervention after 5 years...
  8. Senarathna L, Jayamanna S, Kelly P, Buckley N, Dibley M, Dawson A. Changing epidemiologic patterns of deliberate self poisoning in a rural district of Sri Lanka. BMC Public Health. 2012;12:593 pubmed
    Acute poisoning is a major public health issue in many parts of the world. The epidemiology and the mortality rate is higher in low and middle income countries, including Sri Lanka...
  9. Singh S, Aggarwal A, Oberoi S, Aggarwal K, Thind A, Bhullar D, et al. Study of poisoning trends in north India--a perspective in relation to world statistics. J Forensic Leg Med. 2013;20:14-8 pubmed publisher
    ..contributed significantly to increase the crop yield while on the other hand has led to sharp increase in the poisoning cases in the region...

More Information

Publications62

  1. Heppner H, Christ M, Gosch M, Muhlberg W, Bahrmann P, Bertsch T, et al. Polypharmacy in the elderly from the clinical toxicologist perspective. Z Gerontol Geriatr. 2012;45:473-8 pubmed
    ..Polypharmacy is closely associated with multimorbidity in the elderly and can lead to problems and drug interactions...
  2. Sawalha A. Deliberate self-poisoning: a study from Nablus. Int J Adolesc Med Health. 2012;24:373-7 pubmed publisher
    ..studies haves been published to describe the patterns and rates of deliberate self-harm, particularly self-poisoning, in the Palestinian Authority...
  3. Bateman D, Dear J, Thanacoody H, Thomas S, Eddleston M, Sandilands E, et al. Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. Lancet. 2014;383:697-704 pubmed publisher
    Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption...
  4. Espinoza T, Bryant S, Aks S. Hyperinsulin therapy for calcium channel antagonist poisoning: a seven-year retrospective study. Am J Ther. 2013;20:29-31 pubmed publisher
    The use of hyperinsulin therapy (HIT) in severe calcium channel antagonist (CCA) poisoning has become a more common therapy within the last decade. The objective of this study is to report 7 years of experience recommending HIT...
  5. Choi Y, Kim Y, Ko Y, Cha E, Kim J, Lee W. Economic burden of acute pesticide poisoning in South Korea. Trop Med Int Health. 2012;17:1534-43 pubmed publisher
    To investigate the magnitude and characteristics of the economic burden resulting from acute pesticide poisoning (APP) in South Korea.
  6. Soltaninejad K, Nelson L, Bahreini S, Shadnia S. Fatal aluminum phosphide poisoning in Tehran-Iran from 2007 to 2010. Indian J Med Sci. 2012;66:66-70 pubmed publisher
    Aluminum phosphide (AlP) is also known as "rice tablet" in Iran. Due to the high incidence of acute AlP poisoning and its associated mortality in Iran, the authorities banned AlP-containing tablets in 2007...
  7. Galicia M, Nogué S, To Figueras J, Echarte J, Iglesias M, Miro O. [Poisoning by liquid ecstasy (GHB) in hospital emergency departments of Barcelona: a 2-years study]. Med Clin (Barc). 2008;130:254-8 pubmed
    ..To describe the epidemiological profile and clinical manifestations, we analyzed cases of poisoning by GHB attended by the Emergency Departments (ED) of 2 hospitals of the city of Barcelona.
  8. Lee H, Lin H, Yeh S, Chi C, Guo H. Presentations of patients of poisoning and predictors of poisoning-related fatality: findings from a hospital-based prospective study. BMC Public Health. 2008;8:7 pubmed publisher
    b>Poisoning is a significant public health problem worldwide and is one of the most common reasons for visiting emergency departments (EDs), but factors that help to predict overall poisoning-related fatality have rarely been elucidated...
  9. Shadnia S, Okazi A, Akhlaghi N, Sasanian G, Abdollahi M. Prognostic value of long QT interval in acute and severe organophosphate poisoning. J Med Toxicol. 2009;5:196-9 pubmed
    Suicidal poisoning with organophosphorus (OP) pesticides is common, particularly from rural areas. This highlights the importance of determining an OP poisoning prognosis to decide how aggressive treatment should be...
  10. Abula T, Wondmikun Y. The pattern of acute poisoning in a teaching hospital, north-west Ethiopia. Ethiop Med J. 2006;44:183-9 pubmed
    b>Poisoning by means of hazardous chemicals through ignorance, mishap or intentionally is becoming a serious health problem worldwide. Epidemiological data on this important health issue are, however, scarce in Ethiopia...
  11. Borron S, Baud F. Antidotes for acute cyanide poisoning. Curr Pharm Biotechnol. 2012;13:1940-8 pubmed
    Cyanide poisoning can present in multiple ways, given its widespread industrial use, presence in combustion products, multiple physical forms, and chemical structures. The primary target of toxicity is mitochondrial cytochrome oxidase...
  12. Zhang X, Zhao W, Jing R, Wheeler K, Smith G, Stallones L, et al. Work-related pesticide poisoning among farmers in two villages of Southern China: a cross-sectional survey. BMC Public Health. 2011;11:429 pubmed publisher
    Pesticide poisoning is an important health problem among Chinese farm workers, but there is a paucity of pesticide poisoning data from China...
  13. Schep L, Slaughter R, Temple W, Beasley D. Diethylene glycol poisoning. Clin Toxicol (Phila). 2009;47:525-35 pubmed publisher
    ..Despite DEG's toxicity and associated epidemics of fatal poisonings, a comprehensive review has not been published...
  14. Berend S, Vrdoljak A, Radic B, Kuca K. New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning. Chem Biol Interact. 2008;175:413-6 pubmed publisher
    ..In tabun-poisoned mice very good antidotal efficacy was obtained with K027, K048, and K074, which makes them interesting for future investigation. The combination of HI-6 and atropine is the therapy of choice for soman poisoning.
  15. Hovda K, Jacobsen D. Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. Hum Exp Toxicol. 2008;27:539-46 pubmed publisher
    Fomepizole is now the antidote of choice in methanol poisoning. The use of fomepizole may also change the indications for hemodialysis in these patients. We have addressed this change in a review of articles on methanol poisonings...
  16. Cook R, Allcock R, Johnston M. Self-poisoning: current trends and practice in a U.K. teaching hospital. Clin Med (Lond). 2008;8:37-40 pubmed
    The epidemiology of deliberate self-poisoning presentations to the emergency department (ED) of Ninewells Hospital was reviewed over a six-month period. The results were related to previously published Scottish data...
  17. Charlson F, Degenhardt L, McLaren J, Hall W, Lynskey M. A systematic review of research examining benzodiazepine-related mortality. Pharmacoepidemiol Drug Saf. 2009;18:93-103 pubmed publisher
    ..This paper will review literature examining the association of benzodiazepine use and mortality...
  18. Lai Becker M, Huntington N, Woolf A. Brimonidine tartrate poisoning in children: frequency, trends, and use of naloxone as an antidote. Pediatrics. 2009;123:e305-11 pubmed publisher
    ..We investigated characteristics of childhood exposures to brimonidine-containing products...
  19. Ali R, Jain G, Iqbal Z, Talegaonkar S, Pandit P, Sule S, et al. Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote. Nanomedicine. 2009;5:55-63 pubmed publisher
    ..The formulation seems to have the advantage of early therapeutic drug concentration in blood due to absorption through the lungs as well as sustained action due to absorption from the gut of the remaining portion of the drug...
  20. Mutlu M, Cansu A, Karakas T, Kalyoncu M, Erduran E. Pattern of pediatric poisoning in the east Karadeniz region between 2002 and 2006: increased suicide poisoning. Hum Exp Toxicol. 2010;29:131-6 pubmed publisher
    In the present study, 386 patients with the diagnosis of poisoning admitted to the Pediatric Emergency Unit of Farabi Hospital of Medical Faculty of Karadeniz Technical University between January 2002 and December 2006 were ..
  21. Karasouli E, Owens D, Abbott R, Hurst K, Dennis M. All-cause mortality after non-fatal self-poisoning: a cohort study. Soc Psychiatry Psychiatr Epidemiol. 2011;46:455-62 pubmed publisher
    ..The present study's aim was to describe mortality and risk factors concerning all causes of death after non-fatal self-poisoning.
  22. Phua D, Tsai W, Ger J, Deng J, Yang C. Human Melia azedarach poisoning. Clin Toxicol (Phila). 2008;46:1067-70 pubmed publisher
    ..Although toxicity of this plant has been widely described in veterinary literature, human poisoning is rarely reported. We describe five patients with M. azedarach poisoning who recovered with supportive care.
  23. Sawalha A, Sweileh W, Tufaha M, Al Jabi D. Analysis of the pattern of acute poisoning in patients admitted to a governmental hospital in Palestine. Basic Clin Pharmacol Toxicol. 2010;107:914-8 pubmed publisher
    The objectives were to (i) analyse the pattern of poisoning and (ii) study gender distribution and management protocol of poisoning in patients diagnosed with acute poisoning...
  24. Solodun I, Klevno V, Leliukh T, Maslauskaĭte L, Iaverbaum A, Ermolaeva N, et al. [Forensic-medical evaluation of toxic hepatitis associated with surrogate alcohol poisoning]. Sud Med Ekspert. 2008;51:23-8 pubmed
    Medical cards of 1,116 inpatient victims of surrogate alcohol poisoning and 242 cases of its fatal outcome associated with jaundice were available for analysis form Irkutsk Region and other regions of the Russian Federation in the second ..
  25. Kohli U, Kuttiat V, Lodha R, Kabra S. Profile of childhood poisoning at a tertiary care centre in North India. Indian J Pediatr. 2008;75:791-4 pubmed publisher
    To determine the profile and outcome (discharge from emergency room after observation, admission or death) of pediatric patients presenting with acute poisoning to a tertiary care centre in north India.
  26. Caballero Vallés P, Dorado Pombo S, Díaz Brasero A, García Gil M, Yubero Salgado L, Torres Pacho N, et al. [Epidemiologic survey of acute poisoning in the south area of the Community of Madrid: the VEIA 2004 study]. An Med Interna. 2008;25:262-8 pubmed
    ..We present the 2004 study and compare the results with the previous years...
  27. Thiermann H, Steinritz D, Worek F, Radtke M, Eyer P, Eyer F, et al. Atropine maintenance dosage in patients with severe organophosphate pesticide poisoning. Toxicol Lett. 2011;206:77-83 pubmed publisher
    Although the importance of atropine in therapy of organophosphate (OP) poisoning is generally recognized, its dosing is a matter of debate...
  28. Eisenbach C, Ungur A, Unger J, Stremmel W, Encke J. Admission to intensive care for parasuicide by self-poisoning: variation by time cycles, climate and the lunar cycle. Psychiatry Res. 2008;161:177-84 pubmed publisher
    The aim of this study was to characterize patients after self-poisoning with suicidal intent regarding age, sex and type of substances ingested, as well as to identify temporal variations of attempted suicides and associations with ..
  29. Sabzghabaee A, Eizadi Mood N, Montazeri K, Yaraghi A, Golabi M. Fatality in paraquat poisoning. Singapore Med J. 2010;51:496-500 pubmed
    Acute paraquat (PQ) poisoning continues to be a major public health concern in many developing countries...
  30. Yurumez Y, Durukan P, Yavuz Y, Ikizceli I, Avsarogullari L, Ozkan S, et al. Acute organophosphate poisoning in university hospital emergency room patients. Intern Med. 2007;46:965-9 pubmed
    In the present study, we evaluated patients who were admitted to our emergency department with a diagnosis of organophosphate poisoning and discussed clinical, social and demographic features.
  31. Roberts D, Aaron C. Management of acute organophosphorus pesticide poisoning. BMJ. 2007;334:629-34 pubmed
  32. Greene S, Harris C, Singer J. Gastrointestinal decontamination of the poisoned patient. Pediatr Emerg Care. 2008;24:176-86; quiz 187-9 pubmed publisher
    ..It challenges the accepted precepts of gut decontamination and assesses the utility of syrup of ipecac-induced emesis, orogastric lavage, single-dose-activated charcoal, cathartics, and whole-bowel irrigation...
  33. Ambali S, Akanbi D, Igbokwe N, Shittu M, Kawu M, Ayo J. Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effect of vitamin C. J Toxicol Sci. 2007;32:111-20 pubmed
  34. Senarathna L, Buckley N, Jayamanna S, Kelly P, Dibley M, Dawson A. Validity of referral hospitals for the toxicovigilance of acute poisoning in Sri Lanka. Bull World Health Organ. 2012;90:436-443A pubmed publisher
    To identify the hospital admission data set that best captures the incidence of acute poisoning in rural Sri Lanka.
  35. Woolf A, Erdman A, Nelson L, Caravati E, Cobaugh D, Booze L, et al. Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila). 2007;45:203-33 pubmed
    ..Because of the potential severity of TCA poisoning, transportation by EMS, with close monitoring of clinical status and vital signs en route, should be considered (..
  36. Lee B, Jeung K, Lee H, Jung Y. Mortality rate and pattern following carbamate methomyl poisoning. Comparison with organophosphate poisoning of comparable toxicity. Clin Toxicol (Phila). 2011;49:828-33 pubmed publisher
    Methomyl is a widely used carbamate insecticide. It is known that mortality rate is generally low in carbamate poisoning, but fatalities from methomyl poisoning have been reported...
  37. Montiel V, Gougnard T, Hantson P. Diltiazem poisoning treated with hyperinsulinemic euglycemia therapy and intravenous lipid emulsion. Eur J Emerg Med. 2011;18:121-3 pubmed publisher
    ..The mechanism of action of ILE is not known, including its role in insulin resistance and myocardial metabolism in calcium-channel blocker poisoning.
  38. Senarathna S, Ranganathan S, Dawson A, Buckley N, Fernandopulle B. Management of acute paracetamol poisoning in a tertiary care hospital. Ceylon Med J. 2008;53:89-92 pubmed
    To compare the management of acute paracetamol poisoning with the best evidence available, and to determine the effect of plasma paracetamol level estimation on the management.
  39. Sun M, Ma D, Liu M, Yu Y, Cao D, Ma C, et al. Successful treatment of paraquat poisoning by Xuebijing, an injection concocted from multiple Chinese medicinal herbs: a case report. J Altern Complement Med. 2009;15:1375-8 pubmed publisher
    1,1'-Dimethyl-4,4'-bipyridinium dichloride (Paraquat) poisoning remains a significant global health problem...
  40. Zaloshnja E, Miller T, Jones P, Litovitz T, Coben J, Steiner C, et al. The impact of poison control centers on poisoning-related visits to EDs--United States, 2003. Am J Emerg Med. 2008;26:310-5 pubmed publisher
    This study analyzes the association between center usage rates and the rates of nonadmitted visits to emergency departments (EDs) for poisoning.
  41. Minervino A, Barrêto Júnior R, Ferreira R, Rodrigues F, Headley S, Mori C, et al. Clinical observations of cattle and buffalos with experimentally induced chronic copper poisoning. Res Vet Sci. 2009;87:473-8 pubmed publisher
    The susceptibility of cattle and buffalos to chronic copper poisoning (CCP) was compared by using cattle (n=10) and buffalo (n=10) steers distributed into two copper supplemented (n=6) and two control (n=4) groups...
  42. Chen Y, Wu M, Deng J, Yang C. The epidemiology of glyphosate-surfactant herbicide poisoning in Taiwan, 1986-2007: a poison center study. Clin Toxicol (Phila). 2009;47:670-7 pubmed publisher
    ..However, there are many controversies with regard to the exact causes and determinants of developing severe/death outcome after exposure to GlySH...
  43. Velez L, Gracia R, Neerman M. Ethylene glycol poisoning: current diagnostic and management issues. J Emerg Nurs. 2007;33:342-5 pubmed
  44. Wood S, Heath M, Holland P, Munday R, McGregor G, Ryan K. Identification of a benthic microcystin-producing filamentous cyanobacterium (Oscillatoriales) associated with a dog poisoning in New Zealand. Toxicon. 2010;55:897-903 pubmed publisher
    ..To our knowledge, however, this is the first instance of a benthic microcystin-producing species causing an animal death in New Zealand...
  45. Jain P, Agarwal N, Kumar P, Sengar N, Agarwal N, Akhtar A. Hair dye poisoning in Bundelkhand region (prospective analysis of hair dye poisoning cases presented in Department of Medicine, MLB Medical College, Jhansi). J Assoc Physicians India. 2011;59:415-9 pubmed
    Hair dye (Paraphenylene di-amine, PPD) poisoning has high morbidity and mortality and its incidence has increased dramatically in the past 4 years...
  46. Gjelsvik B, Heyerdahl F, Hawton K. Prescribed medication availability and deliberate self-poisoning: a longitudinal study. J Clin Psychiatry. 2012;73:e548-54 pubmed publisher
    The availability of prescribed medication to patients who engage in deliberate self-poisoning (DSP) is not known, and it is not clear whether patients choose drugs prescribed to them for self-poisoning...
  47. Ahmadi A, Pakravan N, Ghazizadeh Z. Pattern of acute food, drug, and chemical poisoning in Sari City, Northern Iran. Hum Exp Toxicol. 2010;29:731-8 pubmed publisher
    This descriptive and retrospective study was conducted at the poisoning ward of Imam teaching hospital, Sari, Iran, with the aim of evaluating the pattern of poisoning...
  48. Lilley R, Owens D, Horrocks J, House A, Noble R, Bergen H, et al. Hospital care and repetition following self-harm: multicentre comparison of self-poisoning and self-injury. Br J Psychiatry. 2008;192:440-5 pubmed publisher
    Quantitative research about self-harm largely deals with self-poisoning, despite the high incidence of self-injury.
  49. Nissen L, Wong K, Jones A, Roberts D. Availability of antidotes for the treatment of acute poisoning in Queensland public hospitals. Aust J Rural Health. 2010;18:78-84 pubmed publisher
    ..To determine the sufficiency of stock levels of 13 antidotes in Queensland hospitals...
  50. Simonsen K, Normann P, Ceder G, Vuori E, Thordardottir S, Thelander G, et al. Fatal poisoning in drug addicts in the Nordic countries in 2007. Forensic Sci Int. 2011;207:170-6 pubmed publisher
    ..Norway had the highest incidence of drug addict deaths by poisoning followed by Denmark, with 8.24 and 6.92 per 100,000 inhabitants, respectively. The death rates in Finland (4...
  51. Dawson A, Eddleston M, Senarathna L, Mohamed F, Gawarammana I, Bowe S, et al. Acute human lethal toxicity of agricultural pesticides: a prospective cohort study. PLoS Med. 2010;7:e1000357 pubmed publisher
    agricultural pesticide poisoning is a major public health problem in the developing world, killing at least 250,000-370,000 people each year...
  52. Hawkins L, Edwards J, Dargan P. Impact of restricting paracetamol pack sizes on paracetamol poisoning in the United Kingdom: a review of the literature. Drug Saf. 2007;30:465-79 pubmed
    Paracetamol (acetaminophen) is the most common drug taken in overdose in the UK, accounting for 48% of poisoning admissions to hospital and being involved in an estimated 100-200 deaths per year...
  53. Ivanoff C, Ivanoff A, Hottel T. Gallium poisoning: a rare case report. Food Chem Toxicol. 2012;50:212-5 pubmed publisher
    The authors present a case of a college student who suffered acute gallium poisoning as a result of accidental exposure to gallium halide complexes. This is extremely rare and has never been reported in the literature...