tardive dyskinesia


Summary: Drug-related movement disorder characterized by uncontrollable movements in certain muscles. It is associated with a long-term exposure to certain neuroleptic medications (e.g., METOCLOPRAMIDE).

Top Publications

  1. Paton D. Deutetrabenazine: Treatment of hyperkinetic aspects of Huntington's disease, tardive dyskinesia and Tourette syndrome. Drugs Today (Barc). 2017;53:89-102 pubmed publisher
    ..with deutetrabenazine significantly improved chorea in Huntington's disease, the hyperkinetic features of tardive dyskinesia, and tics in Tourette syndrome...
  2. Holder S, Edmunds A, Morgan S. Psychotic and Bipolar Disorders: Antipsychotic Drugs. FP Essent. 2017;455:23-29 pubmed
    ..antipsychotic drugs are more likely to cause adverse effects such as extrapyramidal symptoms and tardive dyskinesia. Adverse effects of second-generation antipsychotic drugs typically are related to metabolic abnormalities ..
  3. Witter D, Holbert R, Suryadevara U. Pharmacotherapy for the treatment of tardive dyskinesia in schizophrenia patients. Expert Opin Pharmacother. 2017;18:965-972 pubmed publisher
    b>Tardive dyskinesia (TD) is an iatrogenic movement disorder most commonly observed in patients with psychotic disorders who are treated with dopamine blocking antipsychotic medications...
  4. Fernandez H, Factor S, Hauser R, Jimenez Shahed J, Ondo W, Jarskog L, et al. Randomized controlled trial of deutetrabenazine for tardive dyskinesia: The ARM-TD study. Neurology. 2017;88:2003-2010 pubmed publisher
    To determine the efficacy and safety of deutetrabenazine as a treatment for tardive dyskinesia (TD)...
  5. Pitzer M, Engelmann G, Stammschulte T. [Tardive movement disorders with antipsychotics – a case of aripirazole-induced tardive dystonia and review of the literature]. Z Kinder Jugendpsychiatr Psychother. 2017;45:325-334 pubmed publisher
    ..b>Tardive dyskinesia (TD), but not tardive dystonia (TDt), also seems to occur less often in adults...
  6. Seeberger L, Hauser R. Valbenazine for the treatment of tardive dyskinesia. Expert Opin Pharmacother. 2017;18:1279-1287 pubmed publisher
    b>Tardive dyskinesia (TD) is a hyperkinetic movement disorder that may result from treatment with antipsychotics or other dopamine receptor blocking agents...
  7. Bielefeldt K. From Harmful Treatment to Secondary Gain: Adverse Event Reporting in Dyspepsia and Gastroparesis. Dig Dis Sci. 2017;62:2999-3013 pubmed publisher
    ..Submissions related to metoclopramide by far exceeded reports about other agents and mostly described tardive dyskinesia or other neurological concerns. They peaked around 2012, driven by submissions through legal workers...
  8. Kim E. Valbenazine: First Global Approval. Drugs. 2017;77:1123-1129 pubmed publisher
    ..Valbenazine has been approved in the USA for the treatment of adults with tardive dyskinesia (TD), is at various stages of development in other countries for TD and is in phase 2 development in the ..