adrenergic agonists


Summary: Drugs that bind to and activate adrenergic receptors.

Top Publications

  1. El Hajj H, Chandrasekhar B, Kadavil E, Oriowo M. Interaction of BKCa channel modulators with adrenergic agonists in the rat aorta is influenced by receptor reserve. Vascul Pharmacol. 2004;41:119-24 pubmed
    Our main objective was to study the interaction of BKCa channel modulators with adrenergic agonists UK 14304 and noradrenaline (NA), acting on alpha1-adrenoceptors, in the rat aorta and how this is affected by receptor reserve...
  2. Al Shahwan M, Al Khenaizan S, Al Khalifa M. Black (samsum) ant induced anaphylaxis in Saudi Arabia. Saudi Med J. 2006;27:1761-3 pubmed
    ..This is the first report of black (samsum) ant allergy in Saudi Arabia. ..
  3. Drake M, Violin J, Whalen E, Wisler J, Shenoy S, Lefkowitz R. beta-arrestin-biased agonism at the beta2-adrenergic receptor. J Biol Chem. 2008;283:5669-76 pubmed
    ..Thus, these studies demonstrate the potential for developing a novel class of 7TMR ligands with a distinct bias for beta-arrestin-mediated signaling. ..
  4. Audet M, Bouvier M. Insights into signaling from the beta2-adrenergic receptor structure. Nat Chem Biol. 2008;4:397-403 pubmed publisher
    ..The different binding modes of these ligands, which correlated with their reported efficacy profiles, suggest that it could be possible to predict the structural determinants of drug signaling efficacies. ..
  5. Pekarova M, Kralova J, Kubala L, Ciz M, Papezikova I, Macickova T, et al. Carvedilol and adrenergic agonists suppress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors. J Physiol Pharmacol. 2009;60:143-50 pubmed
    The interaction of adrenergic agonists and/or antagonists with the adrenergic receptors expressed on immunologically active cells including macrophages plays an important role in regulation of inflammatory responses...
  6. Shpakov A, Shipilov V, Bondareva V. Sensitivity of adenylyl cyclase signaling system of the mollusk Anodonta cygnea ganglions to serotonin and adrenergic agonists. Ann N Y Acad Sci. 2005;1040:466-8 pubmed
  7. Kimura M, Okamoto H, Ogihara M. Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes. J Pharmacol Sci. 2007;103:398-407 pubmed
    We investigated the effects of alpha(1)- and beta(2)-adrenergic agonists on hepatocyte growth factor (HGF)-stimulated mitogen-activated protein kinase (MAPK) isoforms in primary cultures of adult rat hepatocytes...
  8. Kobayashi M. Differential regulation of synaptic transmission by adrenergic agonists via protein kinase A and protein kinase C in layer V pyramidal neurons of rat cerebral cortex. Neuroscience. 2007;146:1772-84 pubmed
    ..There was no significant difference in the effects of adrenergic agonists/antagonists and protein kinase activators/inhibitors between regular spiking and bursting neurons in layer ..
  9. Ma L, Li D, Wang J, He J, Yin Z. Effects of adrenergic agonists on the extrahepatic expression of vitellogenin Ao1 in heart and brain of the Chinese rare minnow (Gobiocypris rarus). Aquat Toxicol. 2009;91:19-25 pubmed publisher
    ..The results also indicated that the production of teleost vtg in vivo can be regulated by not only estrogenic agents, but adrenergic signals as well. ..

More Information

Publications106 found, 100 shown here

  1. Cassidy S, McGovern J, Chan D, Allen H. Effects of commonly used adrenergic agonists on left ventricular function and systemic vascular resistance in young piglets. Am Heart J. 1997;133:174-83 pubmed
    This study compared the effects of high-dose infusions of various adrenergic agonists on cardiovascular function in piglets. We hypothesized that agonists would have different effects on systolic, diastolic, and vascular functions...
  2. Pawelczyk J, Levine B. Heterogeneous responses of human limbs to infused adrenergic agonists: a gravitational effect?. J Appl Physiol (1985). 2002;92:2105-13 pubmed
    ..The relatively greater response to alpha1-adrenergic-receptor stimulation in the calf may represent an adaptive mechanism that limits blood pooling and capillary filtration in the legs during standing. ..
  3. Baker J, Hall I, Hill S. Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses. Mol Pharmacol. 2003;64:679-88 pubmed
  4. Pellati F, Benvenuti S, Melegari M, Firenzuoli F. Determination of adrenergic agonists from extracts and herbal products of Citrus aurantium L. var. amara by LC. J Pharm Biomed Anal. 2002;29:1113-9 pubmed
    ..amara. Taking into account that some authors have reported that l-synephrine may be converted into its d-form by high temperature, this optical isomerization was monitored by the same HPLC method used for the separation of enantiomers...
  5. Vitousek M, Romero L, Tarlow E, Cyr N, Wikelski M. Island tameness: an altered cardiovascular stress response in Galápagos marine iguanas. Physiol Behav. 2010;99:544-8 pubmed publisher
    ..Understanding how the response to predators differs in predator-naïve species could enable the design of maximally effective techniques for inducing an anti-predator response in these vulnerable species...
  6. Corboz M, Rivelli M, Shah H, Boyce C, McCormick K, Chapman R, et al. Role of ?2-adrenoceptors in electrical field stimulation-induced contraction of pig nasal mucosa and pharmacologic characterization of a novel ?2C-adrenoceptor agonist. Am J Rhinol Allergy. 2013;27:84-90 pubmed publisher
  7. Munk M, Jampol L, Cunha Souza E, de Andrade G, Esmaili D, Sarraf D, et al. New associations of classic acute macular neuroretinopathy. Br J Ophthalmol. 2016;100:389-94 pubmed publisher
    ..b>Adrenergic agonists such as lisdexamphetamine may also contribute to the manifestation of AMN.
  8. Bagatto B. Ontogeny of cardiovascular control in zebrafish (Danio rerio): effects of developmental environment. Comp Biochem Physiol A Mol Integr Physiol. 2005;141:391-400 pubmed
    ..Furthermore, long term studies are also needed to assess whether the plasticity measured in this study is adaptive in the evolutionary sense. ..
  9. Desalu I, Kushimo O, Akinlaja O. Adherence to CPR guidelines during perioperative cardiac arrest in a developing country. Resuscitation. 2006;69:517-20 pubmed
    ..The lack of organised simulation practice resulted in deficient knowledge and skills. There is a need for continuing training in basic and advanced resuscitation for all anaesthetists according to the guidelines. ..
  10. Probst A, Maerkl B, Bittinger M, Messmann H. Gastric ischemia following endoscopic submucosal dissection of early gastric cancer. Gastric Cancer. 2010;13:58-61 pubmed publisher
    ..A conservative treatment approach seems justifiable. However, close endoscopic follow up for early recognition and treatment of a resulting stricture is recommended. ..
  11. Le Guen M, Liu N, Tounou F, Augé M, Tuil O, Chazot T, et al. Dexmedetomidine reduces propofol and remifentanil requirements during bispectral index-guided closed-loop anesthesia: a double-blind, placebo-controlled trial. Anesth Analg. 2014;118:946-55 pubmed publisher
    ..Dexmedetomidine also delayed postoperative analgesic use. Dexmedetomidine is a useful adjuvant that reduces anesthetic requirement and provides postoperative analgesia. ..
  12. Kasjan G. [MIRABEGRON--A NEW DRUG FOR TREATMENT OF OVERACTIVE BLADDER]. Urologiia. 2015;:121-4 pubmed
    ..Mirabegron is used in primary patients, or in patients who previously were unsuccessfully treated with anticholinergics. The drug has a good safety profile and causes no side effects typical of anticholinergics. ..
  13. Bella E, Tramacere I, Antonini G, Borghero G, Capasso M, Caponnetto C, et al. Protein misfolding, amyotrophic lateral sclerosis and guanabenz: protocol for a phase II RCT with futility design (ProMISe trial). BMJ Open. 2017;7:e015434 pubmed publisher
    ..The study protocol was approved by the Ethics Committee of IRCCS 'Carlo Besta Foundation' of Milan (Eudract no. 2014-005367-32 Pre-results) based on the Helsinki declaration. ..
  14. Pedroso S, de Souza B, Jurkiewicz A, Juriewicz N, da Silva Júnior E. Effects of in vitro, acute and chronic treatment with fluoxetine on the sympathetic neurotransmission of rat vas deferens. Auton Neurosci. 2017;203:17-24 pubmed publisher
    ..animals were isolated and mounted in an isolated organ bath for the study of the contractions induced by adrenergic agonists, tyramine, 5-HT, Ca2+ or electrical field stimulation...
  15. Jiang Y, Liu L, Steinle J. Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature. Invest Ophthalmol Vis Sci. 2017;58:185-189 pubmed publisher
    ..Compound 49b increased ZO-1 and occludin protein levels, likely leading to decreased permeability. ..
  16. Bégin Heick N. Liver beta-adrenergic receptors, G proteins, and adenylyl cyclase activity in obesity-diabetes syndromes. Am J Physiol. 1994;266:C1664-72 pubmed
    ..Adrenalectomy normalizes the exaggerated response to beta-adrenergic agonists and the number of beta-adrenergic binding sites in the ob/ob mouse...
  17. Golden K, Ren J, O CONNOR J, Dean A, DiCarlo S, Marsh J. In vivo regulation of Na/Ca exchanger expression by adrenergic effectors. Am J Physiol Heart Circ Physiol. 2001;280:H1376-82 pubmed
    ..05) after a 7-day treatment. We conclude that a 7-day treatment of alpha- and beta-adrenergic agonists increases the expression of functional Na/Ca exchangers in adult rat heart.
  18. Tanaka Y, Horinouchi T, Koike K. New insights into beta-adrenoceptors in smooth muscle: distribution of receptor subtypes and molecular mechanisms triggering muscle relaxation. Clin Exp Pharmacol Physiol. 2005;32:503-14 pubmed
  19. Hudson S, Emamdee R, Htut Y, Pal S. The transarterial brachial plexus block for hand and forearm surgery: a review of 1062 cases. Eur J Anaesthesiol. 2007;24:470-2 pubmed
  20. Szepietowska B, Zhu W, Sherwin R. ?2-Adrenergic receptor agonist administration promotes counter-regulatory responses and recovery from hypoglycaemia in rats. Diabetologia. 2013;56:2517-23 pubmed publisher
    ..Our data suggest that formoterol may have therapeutic value to limit the risk of hypoglycaemia in patients with diabetes. ..
  21. Cummins Jacklin E, Boughner E, Kent K, Kwiatkowski D, MacDonald T, Leri F. Memory of a drug lapse: Role of noradrenaline. Neuropharmacology. 2015;99:98-105 pubmed publisher
    ..These findings in rats support the hypothesis that relapse involves memory stabilization processes that can be disrupted by suppression of central NA activity. ..
  22. Fukuda H, Hirakawa T, Iritani N. Nutritional and hormonal regulation of uncoupling protein gene expression in rat adipocytes. J Nutr Sci Vitaminol (Tokyo). 2007;53:426-31 pubmed
    ..Thus, UCP-2 expression appears to be stimulated by energy sources such as glucose and fat, and by regulators of thermogenesis and basal metabolic rate such as T3 and insulin, in contrast to UCP-1 and -3 expression. ..
  23. Yi H, Kim D, Suh J. Hypotensive shock during anesthesia for endovascular embolization. J Neurosurg Anesthesiol. 2008;20:153 pubmed publisher
  24. Petrakis I, Ralevski E, Desai N, Trevisan L, Gueorguieva R, Rounsaville B, et al. Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence. Neuropsychopharmacology. 2012;37:996-1004 pubmed publisher
    ..This study was registered with, registration number NCT00338962 and URL: ..
  25. Phillips C, Fahimi A, Das D, Mojabi F, Ponnusamy R, Salehi A. Noradrenergic System in Down Syndrome and Alzheimer's Disease A Target for Therapy. Curr Alzheimer Res. 2016;13:68-83 pubmed date are NE reuptake inhibitors, presynaptic α-adrenergic receptor antagonists, NE prodrugs, and β-adrenergic agonists. Here we examine alterations in the NE-ergic system in AD and DS and suggest that NE-ergic system rescue is ..
  26. Liu L, Jiang Y, Chahine A, Curtiss E, Steinle J. Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice. Mol Vis. 2017;23:1-7 pubmed
    ..These data indicate that Epac1 may be protective to the retina through inhibition of key inflammatory mediators. ..
  27. Al Shawwa B, Al Huniti N, Weinberger M, Abu Hasan M. Clinical and therapeutic variables influencing hospitalisation for bronchiolitis in a community-based paediatric group practice. Prim Care Respir J. 2007;16:93-7 pubmed
    ..05). Early treatment of bronchiolitis with oral corticosteroid in an outpatient clinic setting was associated with lower hospitalisation rates in patients with a family history of asthma or allergic rhinitis and in RSV-negative patients. ..
  28. Kirillova V, Dzhordzhikiya R, Nigmatullina R. Adrenergic and serotoninergic regulation of myocardial contractility in patients with various morphofunctional changes in the heart resulting from chronic heart failure. Bull Exp Biol Med. 2007;144:501-3 pubmed
    ..During left ventricular hypertrophy, the strength of myocardial contraction in response to serotonin exceeded that induced by epinephrine and was realized via 5-HT2 receptors. ..
  29. Xu Y, Ventura S. Extracts of bark from the traditional Chinese herb Phellodendron amurense inhibit contractility of the isolated rat prostate gland. J Ethnopharmacol. 2010;127:196-9 pubmed publisher
    ..To assess the effectiveness of the traditional Chinese herb Phellodendron amurense in treating urological disorders...
  30. Gill K, Bayart C, Desai R, Golden A, Raimer P, Tamburro J. Brimonidine Toxicity Secondary to Topical Use for an Ulcerated Hemangioma. Pediatr Dermatol. 2016;33:e232-4 pubmed publisher
  31. Beier J, Fuhr R, Seoane B, Massana E, de Miquel G, Pujol H, et al. Efficacy, safety, and tolerability of once-daily abediterol in patients with stable, persistent asthma: a Phase II, randomized, 7-day, crossover study. Pharmacol Res Perspect. 2017;5: pubmed publisher
    ..Abediterol 2.5, 5, and 10 ?g once daily achieved statistically and clinically significant improvements in pulmonary function versus placebo over 7 days and demonstrated a safety and tolerability profile comparable with placebo...
  32. Mastrianni K, Metavarayuth K, Brewer W, Wang Q. Analysis of 10 β-agonists in pork meat using automated dispersive pipette extraction and LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2018;1084:64-68 pubmed publisher
    An analytical procedure for the analysis of 10 β-adrenergic agonists (cimaterol, terbutaline, salbutamol, isoxsuprine, ractopamine, cimbuterol, clenbuterol, brombuterol, mabuterol and mapenterol) in pork meat was developed and ..
  33. Davidsen J, Lambrechtsen J, Egstrup K. [ST elevation myocardial infarction after therapeutic injection of adrenaline]. Ugeskr Laeger. 2006;168:1137-8 pubmed
    ..This patient had an asymptomatic RCA stenosis that probably became symptomatic due to coronary artery spasm related to adrenaline injection and thereby presented symptoms and signs of AMI. ..
  34. Chamberlain S, Muller U, Blackwell A, Robbins T, Sahakian B. Noradrenergic modulation of working memory and emotional memory in humans. Psychopharmacology (Berl). 2006;188:397-407 pubmed
    ..Future research directions are discussed in relation to neuroimaging techniques, functional central nervous system polymorphisms and study designs. ..
  35. Hongo M, Fujisawa S, Adachi T, Shimbo T, Shibata S, Ohba T, et al. Age-related effects of dexmedetomidine on myocardial contraction and coronary circulation in isolated guinea pig hearts. J Pharmacol Sci. 2016;131:118-25 pubmed publisher
    ..The age-related changes in ? adrenoceptor subtypes may be linked to the cardiodepressant effects of dexmedetomidine. ..
  36. Gerresheim G, Brederlau J, Schwemmer U. [Dexmedetomidine in the treatment of acute alcohol withdrawal delirium]. Anaesthesist. 2016;65:525-31 pubmed publisher
    ..Case studies with dexmedetomidine in alcohol withdrawal syndrome show the safety of its application and a benzodiazepine-sparing effect. Its incorporation in escalating intensive care therapy of severe cases could be appropriate. ..
  37. Marquis R, Whitson J. Management of glaucoma: focus on pharmacological therapy. Drugs Aging. 2005;22:1-21 pubmed
    ..The introduction of a variety of well tolerated and potent medications over the past few years now allows the clinician to choose a treatment regimen on an individual patient basis and thereby treat this disorder more effectively. ..
  38. Marin E, Jozsef L, Di Lorenzo A, Held K, Luciano A, Melendez J, et al. The Protein Acyl Transferase ZDHHC21 Modulates ?1 Adrenergic Receptor Function and Regulates Hemodynamics. Arterioscler Thromb Vasc Biol. 2016;36:370-9 pubmed publisher
    ..This is to our knowledge the first demonstration of a ZDHHC isoform affecting vascular function in vivo and identifies a novel molecular mode of regulation of vascular tone and blood pressure. ..
  39. Zhu Q, Cai F, Zhang J, Zhao K, Deng A, Li J. Highly sensitive electrochemiluminescent immunosensor based on gold nanoparticles-functionalized zinc oxide nanorod and poly(amidoamine)-graphene for detecting brombuterol. Biosens Bioelectron. 2016;86:899-906 pubmed publisher
    b>adrenergic agonists (?-agonists) recognized as a growth promoter will reflect the health of human. Sensitive detection of ?-agonists in foodstuff is valuable for the health of animals and human...
  40. Coelho M, Soares Silva C, Brandão D, Marino F, Cosentino M, Ribeiro L. ?-Adrenergic modulation of cancer cell proliferation: available evidence and clinical perspectives. J Cancer Res Clin Oncol. 2017;143:275-291 pubmed publisher
    ..types express both ?1- and ?2-AR, with the exception of neuroblastoma only seeming to express ?2-AR; (2) adrenergic agonists are able to increase proliferation of several types of cancers; (3) the proliferative effect seems to be ..
  41. Krüger B, Kurmann J, Corti N, Spahn D, Bettex D, Rudiger A. Dexmedetomidine-Associated Hyperthermia: A Series of 9 Cases and a Review of the Literature. Anesth Analg. 2017;125:1898-1906 pubmed publisher
    ..The underlying mechanisms and risk factors are uncertain and require further research...
  42. Paradis N, Wenzel V, Southall J. Pressor drugs in the treatment of cardiac arrest. Cardiol Clin. 2002;20:61-78, viii pubmed
    ..Other agents appear promising. This article addresses pressor drugs and adrenergic agonists, including a review of their history, basic science, mechanism of action, and efficacy...
  43. Simons K, Simons F. Epinephrine and its use in anaphylaxis: current issues. Curr Opin Allergy Clin Immunol. 2010;10:354-61 pubmed publisher
  44. Clinckers R, Zgavc T, Vermoesen K, Meurs A, Michotte Y, Smolders I. Pharmacological and neurochemical characterization of the involvement of hippocampal adrenoreceptor subtypes in the modulation of acute limbic seizures. J Neurochem. 2010;115:1595-607 pubmed publisher
  45. Malling H, Hansen K, Mosbech H. [Indication for adrenalin autoinjector after anaphylaxis]. Ugeskr Laeger. 2012;174:1741-3 pubmed
    ..The recommended dose of adrenaline is 0.15 mg for children up to 20 kg and 0.30 mg for larger children and adults. ..
  46. Gallego Ligorit L, Vives M, Vallés Torres J, Sanjuán Villarreal T, Pajares A, Iglesias M. Use of Dexmedetomidine in Cardiothoracic and Vascular Anesthesia. J Cardiothorac Vasc Anesth. 2018;32:1426-1438 pubmed publisher
    ..The benefits of dexmedetomidine in critically ill patients and in cardiac, electrophysiology-related, vascular, and thoracic procedures are discussed. ..
  47. Gil D, Wang J, Gu C, Donello J, Cabrera S, Al Chaer E. Role of sympathetic nervous system in rat model of chronic visceral pain. Neurogastroenterol Motil. 2016;28:423-31 pubmed publisher
    ..The findings further suggest that treatments that decrease sympathetic outflow or block activation of adrenergic receptors on sensory nerves could be beneficial in the treatment of generalized pain syndromes. ..
  48. de Jong J, Wouters R, Boulet N, Cannon B, Nedergaard J, Petrovic N. The β3-adrenergic receptor is dispensable for browning of adipose tissues. Am J Physiol Endocrinol Metab. 2017;312:E508-E518 pubmed publisher
    ..Nonetheless, the present data indicate that the β3-adrenergic receptor is dispensable for cold-induced transcriptional activation in both classical brown and, as opposed to earlier studies, brite/beige cells. ..
  49. Choi H, Lee Y, Yeon S, Lee H, Lee H. Effects of anti-glaucoma drugs on resistive index of the medial long posterior ciliary artery using color Doppler imaging in Beagle dogs. J Vet Sci. 2011;12:99-101 pubmed
    ..05) or dipivefrin (p < 0.05). Pilocarpine showed no effects on RI values after topical administration. The results suggest that some anti-glaucoma drugs could affect ophthalmic blood flow. ..
  50. Breuer C, Wachall B, Gerbeth K, Abdel Tawab M, Fuhr U. Pharmacokinetics and pharmacodynamics of moist inhalation epinephrine using a mobile inhaler. Eur J Clin Pharmacol. 2013;69:1303-10 pubmed publisher
    ..This suggests that administration of epinephrine via a suitable pocket inhaler device may be beneficial in ambulatory emergency treatment of systemic hypersensitivity reactions. EudraCT number: 2010-021493-11. ..
  51. Shaver K, Adams C, Weiss S. Acute myocardial infarction after administration of low-dose intravenous epinephrine for anaphylaxis. CJEM. 2006;8:289-94 pubmed
    ..The authors were able to identify only 2 other case reports where therapeutic doses of epinephrine have been reported to cause this phenomenon. ..
  52. Janwitayanujit S. Anaphylaxis. J Med Assoc Thai. 2007;90:195-200 pubmed
    ..Since life-threatening manifestations may recur during the recurrent phase, it may be necessary to observe the patients for up to 48 hours after apparent recovery from an anaphylactic episode. ..
  53. Minorics R, Gaspar R, Gál A, Klukovits A, Falkay G. Progesterone decreases the relaxing effect of the beta3-adrenergic receptor agonist BRL 37344 in the pregnant rat myometrium. Reproduction. 2009;138:383-90 pubmed publisher
    ..The inhibitory effect of progesterone on the functional activity of the beta(3)-ARs may have important consequences in the case of human application if this effect is also demonstrated in pregnant human myometrial tissue. ..
  54. Salingre A, Klosen P, Pevet P, Simonneaux V. Daytime gating in the Syrian hamster pineal gland. J Neuroendocrinol. 2009;21:760-9 pubmed publisher
    ..the daily cycle but reached the highest levels at early day, when gene expression can be induced by adrenergic agonists. Additionally, CREB phosphorylation was subjected to the same daily gating with an adrenergic induction ..
  55. Methven L, McBride M, Wallace G, McGrath J. The alpha 1B/D-adrenoceptor knockout mouse permits isolation of the vascular alpha 1A-adrenoceptor and elucidates its relationship to the other subtypes. Br J Pharmacol. 2009;158:209-24 pubmed publisher
    ..The alpha(1B/D)-KO provides robust assays for the alpha(1A)-adrenoceptor and takes us closer to understanding multi-receptor subtype interactions. ..
  56. Fernando A, Economidou D, Theobald D, Zou M, Newman A, Spoelder M, et al. Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists. Psychopharmacology (Berl). 2012;219:341-52 pubmed publisher
    ..These findings indicate that high impulsivity can be ameliorated in rats by drugs that mimic the effects of DA and NA, just as in ADHD, and that activation of D2/3 receptors selectively decreases high impulsivity on the 5CSRTT. ..
  57. Yalcin S, Ertunc M, Ardıçlı B, Kabakus I, Tas T, Sara Y, et al. Ureterovesical junction obstruction causes increment in smooth muscle contractility, and cholinergic and adrenergic activity in distal ureter of rabbits. J Pediatr Surg. 2013;48:1954-61 pubmed publisher
    ..We evaluated smooth muscle contractility, and cholinergic, adrenergic and serotonergic activity of rabbit distal ureters after ureterovesical junction (UVJ) obstruction...
  58. Guo R, Xue Q, Qian Y, Hu Y, Tan J. The Effects of Ephedrine and Phenylephrine on Placental Vascular Resistance During Cesarean Section Under Epidual Anesthesia. Cell Biochem Biophys. 2015;73:687-93 pubmed publisher
    ..The discrepancy between the results of human and animal studies may be related to species differences and the mechanism of human placental vascular remodeling. ..
  59. Tahsili Fahadan P, Yahyavi Firouz Abadi N, Khoshnoodi M, Motiei Langroudi R, Tahaei S, Ghahremani M, et al. Agmatine potentiates morphine-induced conditioned place preference in mice: modulation by alpha2-adrenoceptors. Neuropsychopharmacology. 2006;31:1722-32 pubmed
    ..Our results indicate that pretreatment of animals with agmatine enhances the rewarding properties of morphine via a mechanism which may involve alpha2-adrenergic receptors. ..
  60. Naumann G, Koelbl H. Pharmacotherapy of female urinary incontinence. J Br Menopause Soc. 2005;11:160-5 pubmed
    ..The past few years have seen significant advances in the pharmacotherapy of overactive bladder and stress incontinence. The review examines the evidence regarding their benefits and side-effects. ..
  61. Sawa M, Harada H. Recent developments in the design of orally bioavailable beta3-adrenergic receptor agonists. Curr Med Chem. 2006;13:25-37 pubmed
    ..This review summarizes recent advances in beta3-AR agonists with an emphasis on recent attempts to create potent, selective and orally bioavailable small-molecule agonists. ..
  62. Singer M. Catecholamine treatment for shock--equally good or bad?. Lancet. 2007;370:636-7 pubmed
  63. Copeland J, Dzialowski E. Effects of hypoxic and hyperoxic incubation on the reactivity of the chicken embryo (Gallus gallus) ductus arteriosi in response to catecholamines and oxygen. Exp Physiol. 2009;94:152-61 pubmed publisher
    ..Incubation in hypoxia significantly delays the maturation of DA, while incubation in hyperoxia accelerates development. ..
  64. Van der Sterren S, Agren P, Zoer B, Kessels L, Blanco C, Villamor E. Morphological and functional alterations of the ductus arteriosus in a chicken model of hypoxia-induced fetal growth retardation. Pediatr Res. 2009;65:279-84 pubmed publisher
    ..chronic in ovo hypoxia-induced growth retardation in fetal chickens and altered the response of the DA to adrenergic agonists and to endothelium-dependent and -independent relaxing agents...
  65. Rietz A, Spiers J. The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatases. Br J Pharmacol. 2012;166:1225-43 pubmed publisher
  66. Castro Diaz D, Amoros M. Pharmacotherapy for stress urinary incontinence. Curr Opin Urol. 2005;15:227-30 pubmed
    ..this condition has remained in the off-label prescription of some products particularly estrogens and alpha-adrenergic agonists. In this review we provide an update of the most recent developments on the pharmacological therapy for ..
  67. Ring C, Idriss S, Neu W. Variability of action potential duration in pharmacologically induced long QT syndrome type 1. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4520-2 pubmed publisher
    ..Chromanol preferentially changes APD variability in the midwall. Infusing epinephrine returns the variability to near-control levels. These results differ substantially from clinical studies and show the need for further study. ..
  68. Realini T. A history of glaucoma pharmacology. Optom Vis Sci. 2011;88:36-8 pubmed publisher
    ..In addition, some unmet needs that persist in glaucoma pharmacology are discussed. ..
  69. Aboukhoudir F, Rekik S. Left ventricular systolic function deterioration during dobutamine stress echocardiography as an early manifestation of diabetic cardiomyopathy and reversal by optimized therapeutic approach. Int J Cardiovasc Imaging. 2012;28:1329-39 pubmed publisher
    ..This specific condition could be largely reversed through an optimized therapy based on a tighter metabolic control and a more stringent renin-angiotensin-aldosterone system inhibition. ..
  70. Lopes G, Smaili S, Neto A, Vladimirova I, Jurkiewicz A, Jurkiewicz N. Aging-induced decrease of cholinergic response and calcium sensitivity on rat jejunum contractions. J Gerontol A Biol Sci Med Sci. 2007;62:264-70 pubmed
    ..Changes were not detected for relaxation by adrenergic agonists. In conclusion, aging caused a decrease of MCh potency, which is probably related to the reduction of ..
  71. Chinushi M, Izumi D, Iijima K, Ahara S, Komura S, Furushima H, et al. Antiarrhythmic vs. pro-arrhythmic effects depending on the intensity of adrenergic stimulation in a canine anthopleurin-A model of type-3 long QT syndrome. Europace. 2008;10:249-55 pubmed publisher
    ..Since beta-adrenergic blockade suppressed epinephrine-induced PVC and polymorphic VA, it might be considered for supplemental therapy to suppress VA in patients presenting with LQT3. ..
  72. Abrar H, Aftab M. Study of alteration of adrenergic receptor response by chronic use of lisinopril: an ACE inhibitor. Pak J Pharm Sci. 2013;26:421-3 pubmed
    ..05).Therefore it is suggested to use higher doses of adrenaline in cardiac units in patients who have used therapeutic doses of lisinopril for longer periods provided it is supported by clinical studies. ..
  73. Arai S, Stotts N, Puntillo K. Thirst in critically ill patients: from physiology to sensation. Am J Crit Care. 2013;22:328-35 pubmed publisher
    ..thirst, is subject to the tight osmoregulation of the renin-angiotensin aldosterone system and accompanying adrenergic agonists. Understanding the essential role that thirst plays in salt and water regulation can provide clinicians ..
  74. Casella G, Bonforte G, Corso R, Buda C, Corti G, Cambareri A, et al. Rectal bleeding by Dieulafoy-like lesion: successful endoscopic treatment. G Chir. 2005;26:415-8 pubmed
    ..The arteriographic diagnosis associated to endoscopic treatment by epinephrine and BICAP enabled a successful therapy. ..
  75. Pouessel G, Deschildre A, Castelain C, Sardet A, Sagot Bevenot S, de Sauve Boeuf A, et al. Parental knowledge and use of epinephrine auto-injector for children with food allergy. Pediatr Allergy Immunol. 2006;17:221-6 pubmed
    ..The use of auto-injectors was not adequately demonstrated. The prescription of epinephrine for food-allergic children at risk of anaphylaxis requires accurate diagnosis, educational programs, information, and follow up. ..
  76. Shi T, Gaivin R, McCune D, Gupta M, Perez D. Dominance of the alpha1B-adrenergic receptor and its subcellular localization in human and TRAMP prostate cancer cell lines. J Recept Signal Transduct Res. 2007;27:27-45 pubmed
  77. Guntz E, Van den Broeck V, Dereeper E, El Founas W, Sosnowski M. Ultrasound-guided block of the brachial plexus at the humeral canal. Can J Anaesth. 2009;56:109-14 pubmed publisher
    ..We describe an approach to, and the feasibility of ultrasound-guided block of the brachial plexus at the humeral canal. Further study will be required to establish the effectiveness and the safety of this technique. ..
  78. Carey R, DePalma G, Shanahan A, Damianopoulos E, Müller C, Huston J. Effects on spontaneous and cocaine-induced behavior of pharmacological inhibition of noradrenergic and serotonergic systems. Pharmacol Biochem Behav. 2008;89:54-63 pubmed
    ..While both Clonidine and 8-OHDPAT can substantially attenuate a number of cocaine behavioral effects, these inhibitory effects appear to be secondary to reductions in the behavioral baseline rather than reversals of cocaine effects. ..
  79. Görnemann T, Villalón C, Centurión D, Pertz H. Phenylephrine contracts porcine pulmonary veins via alpha(1B)-, alpha(1D)-, and alpha(2)-adrenoceptors. Eur J Pharmacol. 2009;613:86-92 pubmed publisher
    ..It is concluded that, in addition to alpha(1B)- and alpha(1D)-adrenoceptors, phenylephrine can stimulate alpha(2)-adrenoceptors in porcine pulmonary veins. ..
  80. Zhou L, Sleiman M, Ferronato C, Chovelon J, de Sainte Claire P, Richard C. Sulfate radical induced degradation of ?2-adrenoceptor agonists salbutamol and terbutaline: Phenoxyl radical dependent mechanisms. Water Res. 2017;123:715-723 pubmed publisher
    ..The present work could help for a better understanding of the difference in oxidation reactivity of substituted phenols widely present in natural waters. ..
  81. Nai Q, Dong H, Hayar A, Linster C, Ennis M. Noradrenergic regulation of GABAergic inhibition of main olfactory bulb mitral cells varies as a function of concentration and receptor subtype. J Neurophysiol. 2009;101:2472-84 pubmed publisher
  82. Creech C, Neumann D. Changes to euchromatin on LAT and ICP4 following reactivation are more prevalent in an efficiently reactivating strain of HSV-1. PLoS ONE. 2010;5:e15416 pubmed publisher
    ..Our results implicate that chromatin remodeling is an early and essential step involved in the process of in vivo HSV-1 reactivation. ..
  83. Sanghvi M, Ramamoorthy A, Strait J, Wainer I, Moaddel R. Development and validation of a sensitive LC-MS/MS method for the determination of fenoterol in human plasma and urine samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2013;933:37-43 pubmed publisher
    ..The data suggest that a non-racemic mixture of the Fen enantiomers may provide better bioavailability of the active (R,R')-Fen for use in the treatment of cardiovascular disease. ..
  84. Ding X, Lichti K, Kim I, Gonzalez F, Staudinger J. Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha. J Biol Chem. 2006;281:26540-51 pubmed
  85. Järvinen K, Sicherer S, Sampson H, Nowak Wegrzyn A. Use of multiple doses of epinephrine in food-induced anaphylaxis in children. J Allergy Clin Immunol. 2008;122:133-8 pubmed publisher
    ..Prospective studies are necessary to identify risk factors for severe anaphylaxis and to establish rational guidelines for prescribing multiple epinephrine autoinjectors for children with food allergy. ..
  86. Pérez Piñero C, Bruzzone A, Sarappa M, Castillo L, Luthy I. Involvement of ?2- and ?2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation. Br J Pharmacol. 2012;166:721-36 pubmed publisher
    ..The ?-adrenoceptor agonists were as effective as the ?(2) -adrenoceptor antagonist rauwolscine, providing possible novel adjuvant treatments for breast cancer. ..
  87. Chinushi M, Sato A, Iijima K, Suzuki K, Hiroshi F, Izumi D, et al. Exercise-related QT interval shortening with a peaked T wave in a healthy boy with a family history of sudden cardiac death. Pacing Clin Electrophysiol. 2012;35:e239-42 pubmed publisher
    ..Genetic analysis did not show the mutation in KCNQ1, KCNH2, KCNE1, KCNE2, KCNJ2, SCN5A genes but revealed single nucleotide polymorphism (C5457T) in SCN5A gene. ..
  88. Klemans R, Le T, Sigurdsson V, Enters Weijnen C, van Hoffen E, Bruijnzeel Koomen C, et al. Management of acute food allergic reactions by general practitioners. Eur Ann Allergy Clin Immunol. 2013;45:43-51 pubmed
    ..Education programs are needed to increase the awareness of GPs to recognize and treat anaphylactic reactions. ..
  89. Wellman P. Modulation of eating by central catecholamine systems. Curr Drug Targets. 2005;6:191-9 pubmed
  90. Smati B, Sadok Boudaya M, Marghli A, Mestiri T, Baccari S, Hantous T, et al. [Management of postoperative chylothorax]. Rev Mal Respir. 2006;23:152-6 pubmed
    ..A chylothorax can occur following any intrathoracic procedure. It is generally straightforward to make the diagnosis but optimal management can be problematic...
  91. Beer A, Lukanov J, Sagorchev P. Effect of Thymol on the spontaneous contractile activity of the smooth muscles. Phytomedicine. 2007;14:65-9 pubmed
    ..By influencing the beta-adrenergic receptors in the adipose cells, it is possible to induce increased synthesis of fatty acids and glycerol, which is a prerequisite for increased heat release. ..
  92. Boatto G, Culeddu N, Testa C, Neri B, Brambilla G, Barbosa J, et al. Identification of a probable new adrenergic agonist by nuclear magnetic resonance and mass spectrometry. Anal Chim Acta. 2007;586:223-7 pubmed
    ..mode, matching the molecular ion and the fragmentation pattern with those of most recently described new adrenergic agonists. After the loss of a ter-butylic group, the structure shows an internal symmetry along with the presence of ..