Summary: Drugs that are used to reduce body temperature in fever.

Top Publications

  1. Froes T, Melo M, Souza G, Castilho M, Soares D. Virtual screening and biological evaluation of novel antipyretic compounds. Chem Biol Drug Des. 2017;90:739-752 pubmed publisher
    Due to the absence of safety of the antipyretics to patients with cardiovascular dysfunction, new targets to treat inflammation have been pursued...
  2. Sullivan J, Farrar H. Fever and antipyretic use in children. Pediatrics. 2011;127:580-7 pubmed publisher
    ..Many parents administer antipyretics even when there is minimal or no fever, because they are concerned that the child must maintain a "normal&..
  3. King D. Question 2: does a failure to respond to antipyretics predict serious illness in children with a fever?. Arch Dis Child. 2013;98:644-6 pubmed publisher
  4. Niven D, Laupland K, Tabah A, Vesin A, Rello J, Koulenti D, et al. Diagnosis and management of temperature abnormality in ICUs: a EUROBACT investigators' survey. Crit Care. 2013;17:R289 pubmed publisher
  5. Bhowmick R, Sarwar M, Dewan S, Das A, Das B, Uddin M, et al. In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosa leaves. Biol Res. 2014;47:56 pubmed publisher
    ..In the context, it can be said that the leaves of L. glutinosa possess remarkable pharmacological effects, and justify its traditional use as analgesic, antipyretic, anti-inflammatory, and thrombolytic agent. ..
  6. Richardson M, Purssell E. Who's afraid of fever?. Arch Dis Child. 2015;100:818-20 pubmed publisher
  7. Khan M, Hamid A, Akram M, Mustafa S, Sami A, Shah S, et al. Antipyretic potential of herbal coded formulation (Pyrexol). Pak J Pharm Sci. 2017;30:195-198 pubmed
    ..It is concluded that herbal coded medicine at a dose of 240mg/kg has marked antipyretic activity in animal models and this strongly supports the ethno pharmacological uses of medicinal plants of this formulation. ..
  8. Luyasu S, Wamelink M, Galanti L, Dive A. Pyroglutamic acid-induced metabolic acidosis: a case report. Acta Clin Belg. 2014;69:221-3 pubmed publisher
    ..Hemodialysis accelerated the clearance of the accumulated organic acid, and was followed by a sustained clinical improvement. ..
  9. Stretti F, Gotti M, Pifferi S, Brandi G, Annoni F, Stocchetti N. Body temperature affects cerebral hemodynamics in acutely brain injured patients: an observational transcranial color-coded duplex sonography study. Crit Care. 2014;18:552 pubmed publisher
    ..When cerebral compliance is reduced and compensation mechanisms are exhausted, even modest temperature changes can greatly affect ICP. ..

More Information


  1. Johnson R, Rice A. Clinical practice. Postherpetic neuralgia. N Engl J Med. 2014;371:1526-33 pubmed publisher
  2. Forray C, Buller R. Challenges and opportunities for the development of new antipsychotic drugs. Biochem Pharmacol. 2017;143:10-24 pubmed publisher
  3. Shah M, Parveen Z, Khan M. Evaluation of antioxidant, anti-inflammatory, analgesic and antipyretic activities of the stem bark of Sapindus mukorossi. BMC Complement Altern Med. 2017;17:526 pubmed publisher
    ..The resulted obtained in this study suggested the therapeutic importance of stem bark of S. mukorossi in inflammatory related disorders. ..
  4. Teagle A, Powell C. Is fever phobia driving inappropriate use of antipyretics?. Arch Dis Child. 2014;99:701-2 pubmed
  5. Raju G, Moghal M, Hossain M, Hassan M, Billah M, Ahamed S, et al. Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation. Biol Res. 2014;47:55 pubmed publisher
  6. Uchida N, Silva Filho S, Aguiar R, Wiirzler L, Cardia G, Cavalcante H, et al. Protective Effect of Cymbopogon citratus Essential Oil in Experimental Model of Acetaminophen-Induced Liver Injury. Am J Chin Med. 2017;45:515-532 pubmed publisher
    ..LGO inhibited neutrophil migration and exhibited anti-oxidant activity. Our results suggest that LGO has protective activity against liver toxicity induced by paracetamol. ..