Summary: Peptide hormones that cause an increase in the absorption of GLUCOSE by cells within organs such as LIVER, MUSCLE and ADIPOSE TISSUE. During normal metabolism insulins are produced by the PANCREATIC BETA CELLS in response to increased GLUCOSE. Natural and chemically-modified forms of insulin are also used in the treatment of GLUCOSE METABOLISM DISORDERS such as DIABETES MELLITUS.

Top Publications

  1. Madsbad S. LY2605541--a preferential hepato-specific insulin analogue. Diabetes. 2014;63:390-2 pubmed publisher
  2. Gianello P, Mourad N, Cozzi E. Immunoisolation of Human or Xenogeneic Insulin-Producing Cells: The Next Step for Treating Patients With Type 1 Diabetes?. Transplantation. 2016;100:1592-4 pubmed publisher
  3. Reid T, Schafer F, Brusko C. Higher concentration insulins: an overview of clinical considerations. Postgrad Med. 2017;129:554-562 pubmed publisher
    ..Higher concentration insulins have some unique safety and efficacy considerations...
  4. Mora P. Addressing Unmet Needs With Injectable Medications in Type 2 Diabetes Treatment: Basal insulins. J Fam Pract. 2017;66:S7-S11 pubmed
    ..To approximate this physiologic state, 2 general types of insulin formulations have been developed. Basal insulins are intended to address the body's basal metabolic needs over 24 hours, and prandial (or bolus) insulins to ..
  5. Baron H. Addressing Unmet Needs With Injectable Medications in Type 2 Diabetes Treatment: Using Combinations of a Basal Insulin and a Glucagon-Like Peptide-1 Receptor Agonist. J Fam Pract. 2017;66:S17-S28 pubmed
    ..This article presents the rationale and data for combining a basal insulin with a GLP-1RA, including as fixed-ratio products...