light signal transduction


Summary: The conversion of absorbed light energy into molecular signals.

Top Publications

  1. Gasser C, Dean C. Growth and development: a broad view of fine detail. Curr Opin Plant Biol. 2009;12:1-3 pubmed publisher
  2. Kaylor J, Xu T, Ingram N, Tsan A, Hakobyan H, Fain G, et al. Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. Nat Commun. 2017;8:16 pubmed publisher
    ..Here the authors show that mammalian photoreceptors also regenerate opsin pigments in light through photoisomerization of N-ret-PE (N-retinylidene-phosphatidylethanolamine. ..
  3. Expósito Rodríguez M, Laissue P, Yvon Durocher G, Smirnoff N, Mullineaux P. Photosynthesis-dependent H2O2 transfer from chloroplasts to nuclei provides a high-light signalling mechanism. Nat Commun. 2017;8:49 pubmed publisher
    ..Here the authors use a fluorescent hydrogen peroxide sensor to provide evidence that H2O2 is transferred directly from chloroplasts to nuclei to control nuclear gene expression. ..
  4. Dikic I, Robertson M. Ubiquitin ligases and beyond. BMC Biol. 2012;10:22 pubmed publisher
  5. Saari P, French A, Torkkeli P, Liu H, Immonen E, Frolov R. Distinct roles of light-activated channels TRP and TRPL in photoreceptors of Periplaneta americana. J Gen Physiol. 2017;149:455-464 pubmed publisher
    ..We conclude that TRPL channels provide high-gain/high-noise transduction, suitable for vision in dim light, whereas transduction by TRP channels is relatively low-gain/low-noise and allows better information transfer in bright light. ..
  6. Peinado Allina G, Fortenbach C, Naarendorp F, Gross O, Pugh E, Burns M. Bright flash response recovery of mammalian rods in vivo is rate limited by RGS9. J Gen Physiol. 2017;149:443-454 pubmed publisher
    ..These results are important for understanding retinal circuitry, in particular as modeled in the large literature that addresses the relationship between the kinetics and sensitivity of retinal responses and visual perception. ..
  7. Rose K, Walston S, Chen J. Separation of photoreceptor cell compartments in mouse retina for protein analysis. Mol Neurodegener. 2017;12:28 pubmed publisher
  8. Zhu J, Hu L, Li L, Huang X, Shi H. Comparison of phenotypic and global gene expression changes in Xenopus tropicalis embryos induced by agonists of RAR and RXR. Toxicol Appl Pharmacol. 2017;330:40-47 pubmed publisher
    ..Our data indicates that not only RXR-RAR but also RXR-PPAR plays important roles in the control of metabolism with retinoid treatment in X. tropicalis embryos. ..
  9. Kim S, Kim H, Chung S, Lee J. DHU1 negatively regulates UV-B signaling via its direct interaction with COP1 and RUP1. Biochem Biophys Res Commun. 2017;491:285-290 pubmed publisher
    ..This study will serve as a platform to further understand more detailed action mechanism of DHU1 in UV-B response and DHU1-mediated core UV-B signaling in Arabidopsis. ..

More Information


  1. Yu P, Song L, Qin J, Wang J. Capturing the photo-signaling state of a photoreceptor in a steady-state fashion by binding a transition metal complex. Protein Sci. 2017;26:2249-2256 pubmed publisher
    ..The organometallic reagents hold promise as protein engineering tools. This work highlights a novel approach to structurally accessing short lived intermediates of proteins in a steady-state fashion. ..
  2. Hochrein L, Machens F, Messerschmidt K, Mueller Roeber B. PhiReX: a programmable and red light-regulated protein expression switch for yeast. Nucleic Acids Res. 2017;45:9193-9205 pubmed publisher
    ..Time course experiments demonstrate high-level induction over a period of at least 48 h. ..
  3. Foyer C, Ruban A, Noctor G. Viewing oxidative stress through the lens of oxidative signalling rather than damage. Biochem J. 2017;474:877-883 pubmed publisher
    ..Examining the multifaceted roles of ROS as crucial cellular signals, we highlight as an example the loss of photosystem II function called photoinhibition, where photoprotection has classically been conflated with oxidative damage. ..
  4. Gu D, Chen C, Zhao M, Zhao L, Duan X, Duan J, et al. Identification of HDA15-PIF1 as a key repression module directing the transcriptional network of seed germination in the dark. Nucleic Acids Res. 2017;45:7137-7150 pubmed publisher
  5. Olivares A, Han Y, Soto D, Flattery K, Marini J, Mollema N, et al. The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning. Dev Biol. 2017;429:343-355 pubmed publisher
    ..This study supports a role for Nr2c1 in defining the biphasic period of retinal development and specifically influencing the early phase of retinal cell fate. ..
  6. Zhang Y, Li C, Zhang J, Wang J, Yang J, Lv Y, et al. Dissection of HY5/HYH expression in Arabidopsis reveals a root-autonomous HY5-mediated photomorphogenic pathway. PLoS ONE. 2017;12:e0180449 pubmed publisher
    ..Collectively, these results indicate that an organ-specific HY5-mediated pathway controls root photomorphogenic development independently of light signaling in the shoot. ..
  7. Holtkotte X, Ponnu J, Ahmad M, Hoecker U. The blue light-induced interaction of cryptochrome 1 with COP1 requires SPA proteins during Arabidopsis light signaling. PLoS Genet. 2017;13:e1007044 pubmed publisher
    ..Blue light is sensed by the Arabidopsis photoreceptors CRY1 and CRY2 which subsequently initiate light signal transduction by repressing the COP1/SPA E3 ubiquitin ligase...