feeder cells


Summary: Cells used in COCULTURE TECHNIQUES which support the growth of the other cells in the culture. Feeder cells provide auxillary substances including attachment substrates, nutrients, or other factors that are needed for growth in culture.

Top Publications

  1. Zhang Y, Wang S, Wang X, Liao S, Wu Y, Han C. Endogenously produced FGF2 is essential for the survival and proliferation of cultured mouse spermatogonial stem cells. Cell Res. 2012;22:773-6 pubmed publisher
  2. Nishimura T, Hatoya S, Kanegi R, Wijesekera D, Sanno K, Tanaka E, et al. Feeder-independent canine induced pluripotent stem cells maintained under serum-free conditions. Mol Reprod Dev. 2017;84:329-339 pubmed publisher
    ..were dissociated into single cells for passaging, and were maintained on a Matrigel-coated dish without feeder cells in a serum-free medium...
  3. Farahat M, Sathi G, Hara E, Taketa H, Kuboki T, Matsumoto T. MSCs feeder layers induce SMG self-organization and branching morphogenesis. PLoS ONE. 2017;12:e0176453 pubmed publisher
    ..In response to this, we hypothesized that bone marrow derived mesenchymal stem cells (MSCs) could be used as feeder cells to induce salivary epithelial tissues/cells branching...
  4. Ogihara T, Arakawa H, Jomura T, Idota Y, Koyama S, Yano K, et al. Utility of human hepatocyte spheroids without feeder cells for evaluation of hepatotoxicity. J Toxicol Sci. 2017;42:499-507 pubmed publisher
    We investigated the utility of three-dimensionally cultured hepatocytes (spheroids) without feeder cells (Sph(f-)) for the prediction of drug-induced liver injury (DILI) in humans...
  5. Rogers P, Driessnack M, Hiltbold Schwartz E. Analysis of the developmental stages, kinetics, and phenotypes exhibited by myeloid cells driven by GM-CSF in vitro. PLoS ONE. 2017;12:e0181985 pubmed publisher
    ..Finally, within the moMac population we also identified moDC precursor activity (moDP) that could be distinguished from moMac and moDC based on their level of MHC class II expression and developmental plasticity. ..
  6. Streltsova M, Barsov E, Erokhina S, Kovalenko E. Retroviral gene transfer into primary human NK cells activated by IL-2 and K562 feeder cells expressing membrane-bound IL-21. J Immunol Methods. 2017;450:90-94 pubmed publisher
    ..Our findings may facilitate retroviral vector-mediated genetic engineering of human primary NK cells for future immunotherapies. ..
  7. Meleis A, Mahtabfar A, Danish S, Foty R. Dexamethasone-mediated inhibition of Glioblastoma neurosphere dispersal in an ex vivo organotypic neural assay. PLoS ONE. 2017;12:e0186483 pubmed publisher
    ..These doses are 3-30-fold lower than those used to control edema. This study extends our previous in vitro data and identifies the mouse retina as a potential substrate for in vivo studies of GBM dispersal. ..
  8. Mei H, González S, Nakatsu M, Baclagon E, Chen F, Deng S. Human adipose-derived stem cells support the growth of limbal stem/progenitor cells. PLoS ONE. 2017;12:e0186238 pubmed publisher
    ..possible xenobiotic contamination from 3T3s, primary human adipose-derived stem cells (ASCs) were examined as feeder cells to support the expansion of LSCs in vitro...