cell membrane structures

Summary

Summary: Structures which are part of the CELL MEMBRANE or have cell membrane as a major part of their structure.

Top Publications

  1. Lee E, Marcucci M, Daniell L, Pypaert M, Weisz O, Ochoa G, et al. Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science. 2002;297:1193-6 pubmed
    ..These findings support a role of the bilayer-deforming properties of amphiphysin at T-tubules and, more generally, a physiological role of amphiphysin in membrane deformation...
  2. Nevot M, Deroncele V, Messner P, Guinea J, Mercade E. Characterization of outer membrane vesicles released by the psychrotolerant bacterium Pseudoalteromonas antarctica NF3. Environ Microbiol. 2006;8:1523-33 pubmed
    ..antarctica NF3, might function to deliver proteins to the external media, and therefore play an important role in the survival of the bacterium in the extreme Antarctic environment...
  3. Buschman M, Bromann P, Cejudo Martin P, Wen F, Pass I, Courtneidge S. The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation. Mol Biol Cell. 2009;20:1302-11 pubmed publisher
    ..These findings suggest that Tks4 and Tks5 have overlapping, but not identical, functions, and implicate Tks4 in MT1-MMP recruitment and ECM degradation...
  4. Poincloux R, Lizarraga F, Chavrier P. Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. J Cell Sci. 2009;122:3015-24 pubmed publisher
    ..Furthermore, the recent identification of cellular components that control delivery of MT1-MMP to invadopodia brings new insight into mechanisms of cancer-cell invasion and reveals potential pharmacological targets...
  5. Albiges Rizo C, Destaing O, Fourcade B, Planus E, Block M. Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions. J Cell Sci. 2009;122:3037-49 pubmed publisher
    ..Targeting actin-regulatory molecules that specifically promote invadopodium formation is an attractive strategy against cancer-cell invasion...
  6. Hasegawa J, Tokuda E, Tenno T, Tsujita K, Sawai H, Hiroaki H, et al. SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain. J Cell Biol. 2011;193:901-16 pubmed publisher
    ..These results provide new insight into the molecular mechanism of dorsal ruffle formation and its regulation by phosphoinositide metabolism...
  7. DerMardirossian C, Rocklin G, Seo J, Bokoch G. Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling. Mol Biol Cell. 2006;17:4760-8 pubmed
    ..These results suggest that Src-mediated RhoGDI phosphorylation is a novel physiological mechanism for regulating Rho GTPase cytosol membrane-cycling and activity...
  8. Shimada A, Niwa H, Tsujita K, Suetsugu S, Nitta K, Hanawa Suetsugu K, et al. Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell. 2007;129:761-72 pubmed
    ..Furthermore, FBP17 is recruited to clathrin-coated pits in the late stage of CME, indicating its physiological role...
  9. Lee E, Bang J, Park G, Choi D, Kang J, Kim H, et al. Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Proteomics. 2007;7:3143-53 pubmed
    ..This information will help us not only to elucidate the biogenesis and functions of OMV from nonpathogenic and pathogenic bacteria but also to develop vaccines and antibiotics effective against pathogenic strains...
  10. Gu Z, Noss E, Hsu V, Brenner M. Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. J Cell Biol. 2011;193:61-70 pubmed publisher
    ..These findings explain why integrins have long been observed to redistribute through both surface-based and internal routes and identify a new function for macropinocytosis during growth factor-induced cell migration...

Detail Information

Publications105 found, 100 shown here

  1. Lee E, Marcucci M, Daniell L, Pypaert M, Weisz O, Ochoa G, et al. Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science. 2002;297:1193-6 pubmed
    ..These findings support a role of the bilayer-deforming properties of amphiphysin at T-tubules and, more generally, a physiological role of amphiphysin in membrane deformation...
  2. Nevot M, Deroncele V, Messner P, Guinea J, Mercade E. Characterization of outer membrane vesicles released by the psychrotolerant bacterium Pseudoalteromonas antarctica NF3. Environ Microbiol. 2006;8:1523-33 pubmed
    ..antarctica NF3, might function to deliver proteins to the external media, and therefore play an important role in the survival of the bacterium in the extreme Antarctic environment...
  3. Buschman M, Bromann P, Cejudo Martin P, Wen F, Pass I, Courtneidge S. The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation. Mol Biol Cell. 2009;20:1302-11 pubmed publisher
    ..These findings suggest that Tks4 and Tks5 have overlapping, but not identical, functions, and implicate Tks4 in MT1-MMP recruitment and ECM degradation...
  4. Poincloux R, Lizarraga F, Chavrier P. Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. J Cell Sci. 2009;122:3015-24 pubmed publisher
    ..Furthermore, the recent identification of cellular components that control delivery of MT1-MMP to invadopodia brings new insight into mechanisms of cancer-cell invasion and reveals potential pharmacological targets...
  5. Albiges Rizo C, Destaing O, Fourcade B, Planus E, Block M. Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions. J Cell Sci. 2009;122:3037-49 pubmed publisher
    ..Targeting actin-regulatory molecules that specifically promote invadopodium formation is an attractive strategy against cancer-cell invasion...
  6. Hasegawa J, Tokuda E, Tenno T, Tsujita K, Sawai H, Hiroaki H, et al. SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain. J Cell Biol. 2011;193:901-16 pubmed publisher
    ..These results provide new insight into the molecular mechanism of dorsal ruffle formation and its regulation by phosphoinositide metabolism...
  7. DerMardirossian C, Rocklin G, Seo J, Bokoch G. Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling. Mol Biol Cell. 2006;17:4760-8 pubmed
    ..These results suggest that Src-mediated RhoGDI phosphorylation is a novel physiological mechanism for regulating Rho GTPase cytosol membrane-cycling and activity...
  8. Shimada A, Niwa H, Tsujita K, Suetsugu S, Nitta K, Hanawa Suetsugu K, et al. Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell. 2007;129:761-72 pubmed
    ..Furthermore, FBP17 is recruited to clathrin-coated pits in the late stage of CME, indicating its physiological role...
  9. Lee E, Bang J, Park G, Choi D, Kang J, Kim H, et al. Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Proteomics. 2007;7:3143-53 pubmed
    ..This information will help us not only to elucidate the biogenesis and functions of OMV from nonpathogenic and pathogenic bacteria but also to develop vaccines and antibiotics effective against pathogenic strains...
  10. Gu Z, Noss E, Hsu V, Brenner M. Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. J Cell Biol. 2011;193:61-70 pubmed publisher
    ..These findings explain why integrins have long been observed to redistribute through both surface-based and internal routes and identify a new function for macropinocytosis during growth factor-induced cell migration...
  11. Kozlova E, Chernysh A, Moroz V, Kuzovlev A. Analysis of nanostructure of red blood cells membranes by space Fourier transform of AFM images. Micron. 2013;44:218-27 pubmed publisher
    ..The blood intoxication was modeled by adding hemin, furosemide, chlorpromazine and zinc ions into blood, in vitro...
  12. Morin Ganet M, Rambourg A, Deitz S, Franzusoff A, Kepes F. Morphogenesis and dynamics of the yeast Golgi apparatus. Traffic. 2000;1:56-68 pubmed
    ..Retention could arise from intra-compartmental flow of cargo/carrier, hinted at by the varying calibers within a single nodular network. ..
  13. Yamaguchi K, Hata K, Wada T, Moriya S, Miyagi T. Epidermal growth factor-induced mobilization of a ganglioside-specific sialidase (NEU3) to membrane ruffles. Biochem Biophys Res Commun. 2006;346:484-90 pubmed
    ..These results indicate that NEU3 is able to mobilize to membrane ruffles in response to growth stimuli and activate the Rac-1 signaling by co-localization with Rac-1, leading to increased cell motility. ..
  14. Henrich P, Kilian N, Lanzer M, Cyrklaff M. 3-D analysis of the Plasmodium falciparum Maurer's clefts using different electron tomographic approaches. Biotechnol J. 2009;4:888-94 pubmed publisher
    ..Our data show that the different approaches tested all have their merits, revealing different aspects of the complex structure of the Maurer's clefts. ..
  15. Svistounov D, Warren A, McNerney G, Owen D, Zencak D, Zykova S, et al. The Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cells. PLoS ONE. 2012;7:e46134 pubmed publisher
    ..The results are consistent with a sieve-raft interaction, where fenestrations form in non-raft lipid-disordered regions of endothelial cells once the membrane-stabilizing effects of actin cytoskeleton and membrane rafts are diminished. ..
  16. Kopp P, Lammers R, Aepfelbacher M, Woehlke G, Rudel T, Machuy N, et al. The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages. Mol Biol Cell. 2006;17:2811-23 pubmed
    ..This is the first report to implicate a kinesin in podosome regulation and also the first to describe a function for KIF1C in human cells. ..
  17. Goh T, Uchida W, Arakawa S, Ito E, Dainobu T, Ebine K, et al. VPS9a, the common activator for two distinct types of Rab5 GTPases, is essential for the development of Arabidopsis thaliana. Plant Cell. 2007;19:3504-15 pubmed
    ..These results indicate that the two types of plant Rab5 members are functionally differentiated, even though they are regulated by the same activator, VPS9a. ..
  18. Schramp M, Ying O, Kim T, Martin G. ERK5 promotes Src-induced podosome formation by limiting Rho activation. J Cell Biol. 2008;181:1195-210 pubmed publisher
    ..We conclude that ERK5 promotes Src-induced podosome formation by inducing RhoGAP7 and thereby limiting Rho activation. ..
  19. Murphy E, Boxberger J, Colvin R, Lee S, Zahn G, Loor F, et al. Pil1, an eisosome organizer, plays an important role in the recruitment of synaptojanins and amphiphysins to facilitate receptor-mediated endocytosis in yeast. Eur J Cell Biol. 2011;90:825-33 pubmed publisher
    ..Together, these results establish that Pil1 is involved in the recruitment of endocytic proteins to optimize endocytosis. ..
  20. Bandorowicz Pikuła J, Wos M, Pikuła S. [Participation of annexins in signal transduction, regulation of plasma membrane structure and membrane repair mechanisms]. Postepy Biochem. 2012;58:135-48 pubmed
    ..In this review the data are presented that annexins participate in the regulation of membrane structure and may be involved in the calcium-dependent membrane repair mechanisms. ..
  21. Arur S, Uche U, Rezaul K, Fong M, Scranton V, Cowan A, et al. Annexin I is an endogenous ligand that mediates apoptotic cell engulfment. Dev Cell. 2003;4:587-98 pubmed
    ..These results provide novel mechanistic insights into how apoptotic cells are removed and may explain a pathogenic mechanism of chronic inflammatory diseases where annexin I autoantibodies have been described. ..
  22. Pisoni M, Cogotzi L, Frigeri A, Corsi I, Bonacci S, Iacocca A, et al. DNA adducts, benzo(a)pyrene monooxygenase activity, and lysosomal membrane stability in Mytilus galloprovincialis from different areas in Taranto coastal waters (Italy). Environ Res. 2004;96:163-75 pubmed
    ..Overall, the integrated use of biomarkers of exposure and the effects of environmental contaminants on living marine organisms may help to better interpret the impact of pollutants in a marine coastal environment. ..
  23. Li A, Dawson J, Forero Vargas M, Spence H, Yu X, König I, et al. The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol. 2010;20:339-45 pubmed publisher
    ..We provide a potential molecular mechanism for how fascin increases the invasiveness of cancer cells, and we compare invadopodia with invasive filopod-like structures in 3D. ..
  24. Lam B, Anthony E, Hordijk P. Cytoplasmic targeting of the proto-oncogene SET promotes cell spreading and migration. FEBS Lett. 2013;587:111-9 pubmed publisher
    ..Pharmacological inhibition of PP2A did not mimic the effects of SET(?NLS), however, we found that expression of SET and SET(?NLS) increases the levels of the MAP kinases ERK1 and ERK2. ..
  25. Corriden R, Self T, Akong Moore K, Nizet V, Kellam B, Briddon S, et al. Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. EMBO Rep. 2013;14:726-32 pubmed publisher
    ..Our results shed new light on the behaviour of neutrophils and identify the A3AR as a potential target for modulating their function. ..
  26. Kono M, Herrmann S, Loughran N, Cabrera A, Engelberg K, Lehmann C, et al. Evolution and architecture of the inner membrane complex in asexual and sexual stages of the malaria parasite. Mol Biol Evol. 2012;29:2113-32 pubmed publisher
  27. Mital J, Miller N, Dorward D, Dooley C, Hackstadt T. Role for chlamydial inclusion membrane proteins in inclusion membrane structure and biogenesis. PLoS ONE. 2013;8:e63426 pubmed publisher
    ..Overall, it appears that Incs may have an intrinsic ability to induce membrane formation and that individual Incs can induce membranous structures with unique properties. ..
  28. Pan Y, Tseng W, Chang P, Chen H. Phosphorylation of moesin by Jun N-terminal kinase is important for podosome rosette formation in Src-transformed fibroblasts. J Cell Sci. 2013;126:5670-80 pubmed publisher
    ..Taken together, our results unveil a novel role of JNK in podosome rosette formation through the phosphorylation of moesin. ..
  29. Kim G, Klotchkova T, Kang Y. Life without a cell membrane: regeneration of protoplasts from disintegrated cells of the marine green alga Bryopsis plumosa. J Cell Sci. 2001;114:2009-14 pubmed
    ..About a thousand new cells were generated from a single disintegrated branch and 40% of them eventually developed into mature plants. ..
  30. Demchenko A, Yesylevskyy S. Nanoscopic description of biomembrane electrostatics: results of molecular dynamics simulations and fluorescence probing. Chem Phys Lipids. 2009;160:63-84 pubmed publisher
  31. Ecsedy M, Recsan Z. Posterior hyaloid peeling in advanced stages of aggressive posterior ROP. Eur J Ophthalmol. 2011;21:179-82 pubmed
    ..To evaluate the indications and timing of surgical intervention on eyes with aggressive posterior retinopathy of prematurity (ROP)...
  32. Kamaguchi A, Nakayama K, Ichiyama S, Nakamura R, Watanabe T, Ohta M, et al. Effect of Porphyromonas gingivalis vesicles on coaggregation of Staphylococcus aureus to oral microorganisms. Curr Microbiol. 2003;47:485-91 pubmed
    ..aureus, but the yeast-type did not. These results indicate that strains of S. aureus, including MRSA, could adhere to oral biofilms in dental plaque on the tooth surface or in the gingival crevice when P. gingivalis is present. ..
  33. Kondylis V, van Nispen tot Pannerden H, van Dijk S, Ten Broeke T, Wubbolts R, Geerts W, et al. Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells. Autophagy. 2013;9:861-80 pubmed publisher
  34. Cheng J, Huang S, Fan C, Zheng N, Zhang Y, Li S, et al. Metabolomic analysis of alterations in lipid oxidation, carbohydrate and amino acid metabolism in dairy goats caused by exposure to Aflotoxin B1. J Dairy Res. 2017;84:401-406 pubmed publisher
    ..bodies (acetate, ?-hydroxybutyrate), amino acids (citrulline, leucine/isoleucine, valine, creatine) and cell membrane structures (choline, lipoprotein, N-acetyl glycoproteins) in the serum...
  35. Delaguillaumie A, Lagaudrière Gesbert C, Popoff M, Conjeaud H. Rho GTPases link cytoskeletal rearrangements and activation processes induced via the tetraspanin CD82 in T lymphocytes. J Cell Sci. 2002;115:433-43 pubmed
    ..This novel link between a tetraspanin and the Rho GTPase cascade could explain why tetraspanins, which are known to form heterocomplexes, are involved in cell activation, adhesion, growth and metastasis. ..
  36. Hua Z, Graham T. Requirement for neo1p in retrograde transport from the Golgi complex to the endoplasmic reticulum. Mol Biol Cell. 2003;14:4971-83 pubmed
    ..We propose that loss of lipid asymmetry in the cis Golgi perturbs retrograde protein transport to the ER. ..
  37. Wileman T. Aggresomes and autophagy generate sites for virus replication. Science. 2006;312:875-8 pubmed
    ..Here I review the evidence that some viruses induce aggresomes and autophagosomes to generate sites of replication. ..
  38. Schmutz C, Stevens J, Spang A. Functions of the novel RhoGAP proteins RGA-3 and RGA-4 in the germ line and in the early embryo of C. elegans. Development. 2007;134:3495-505 pubmed
    ..We propose that RGA-3/4 and CYK-4 control with which effector molecules RHO-1 interacts at particular sites at the cortex in the zygote and in the germ line. ..
  39. Yu R, Wu J, Liu M, Chen L, Zhu G, Lu H. Physiological and transcriptional responses of Nitrosomonas europaea to TiO2 and ZnO nanoparticles and their mixtures. Environ Sci Pollut Res Int. 2016;23:13023-34 pubmed publisher
    ..In addition, the damage of cell membrane structures and the suppression of cell membrane biogenesis-related gene expressions under the influence of either ..
  40. Angstadt J, Donmoyer J, Stretton A. The number of morphological synapses between neurons does not predict the strength of their physiological synaptic interactions: a study of dendrites in the nematode Ascaris suum. J Comp Neurol. 2001;432:512-27 pubmed
    ..However, the numbers of synapses from this motor neuron were very small relative to inputs from other identified cells. Thus, direct synapses are unlikely to explain the robust nature of this physiological interaction. ..
  41. Sokac A, Wieschaus E. Zygotically controlled F-actin establishes cortical compartments to stabilize furrows during Drosophila cellularization. J Cell Sci. 2008;121:1815-24 pubmed publisher
  42. Sowinski S, Alakoskela J, Jolly C, Davis D. Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1. Methods. 2011;53:27-33 pubmed publisher
    ..Here, we describe detailed protocols for observing membrane nanotubes and HIV-1 trafficking by live cell fluorescence microscopy. ..
  43. Heasman S, Carlin L, Cox S, Ng T, Ridley A. Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. J Cell Biol. 2010;190:553-63 pubmed publisher
    ..Our data indicate that RhoA activity is dynamically regulated at the front and back of T cells to coordinate TEM...
  44. Boulanger C, Scoazec A, Ebrahimian T, Henry P, Mathieu E, Tedgui A, et al. Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction. Circulation. 2001;104:2649-52 pubmed
  45. Ratajczak J, Miekus K, Kucia M, Zhang J, Reca R, Dvorak P, et al. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia. 2006;20:847-56 pubmed
    ..We postulate that ES-MV may efficiently expand HPC by stimulating them with ES-MV expressed ligands (e.g., Wnt-3) as well as increase their pluripotency after horizontal transfer of ES-derived mRNA. ..
  46. Clement C, Tiwari V, Scanlan P, Valyi Nagy T, Yue B, Shukla D. A novel role for phagocytosis-like uptake in herpes simplex virus entry. J Cell Biol. 2006;174:1009-21 pubmed
    ..Collectively, our data suggests a novel mode of uptake by which the virus can infect both professional and nonprofessional phagocytes. ..
  47. Caldieri G, Capestrano M, Bicanova K, Beznoussenko G, Baldassarre M, Buccione R. Polarised apical-like intracellular sorting and trafficking regulates invadopodia formation and degradation of the extracellular matrix in cancer cells. Eur J Cell Biol. 2012;91:961-8 pubmed publisher
  48. Erlandson K, Bisht H, Weisberg A, Hyun S, Hansen B, Fischer E, et al. Poxviruses Encode a Reticulon-Like Protein that Promotes Membrane Curvature. Cell Rep. 2016;14:2084-2091 pubmed publisher
    ..We suggest that A17 is a viral reticulon-like protein that contributes to curvature during biogenesis of the poxvirus membrane. ..
  49. Tatin F, Grise F, Reuzeau E, Genot E, Moreau V. Sodium fluoride induces podosome formation in endothelial cells. Biol Cell. 2010;102:489-98 pubmed publisher
    ..Podosomes are actin-based structures endowed with adhesion and matrix-degradation functions. This study investigates actin cytoskeleton reorganization induced by fluoride in endothelial cells...
  50. Chapman D, Buxser S. Effects of membrane partitioning and other physical chemical properties on the apparent potency of "membrane active" compounds evaluated using red blood cell lysis assays. Anal Biochem. 2002;303:153-66 pubmed
    ..The methods may prove generally useful for distinguishing compounds whose primary activity is membrane destabilization from more interesting and useful pharmacological mechanisms of action...
  51. Anderson L. Discovery of a new cellular structure--the porosome: elucidation of the molecular mechanism of secretion. Cell Biol Int. 2004;28:3-5 pubmed
  52. Colvard M, Ashrafi S, Alonge O, Cordell G. Smokeless tobacco-induced lamellar body abnormalities. Oral Dis. 2006;12:343-8 pubmed
    ..To compare the morphological changes and quantitative distribution of lamellar bodies (Lb) (membrane coating granules) in the hamster cheek pouch epithelium with smokeless tobacco (ST)...
  53. Le Lay S, Li Q, Proschogo N, Rodriguez M, Gunaratnam K, Cartland S, et al. Caveolin-1-dependent and -independent membrane domains. J Lipid Res. 2009;50:1609-20 pubmed publisher
    ..In contrast, the abundance of ordered domains in adherent cells is reduced in Cav1(-/-) compared with WT MEFs, suggesting that cell architecture is critical in maintaining Cav1-induced lipid rafts...
  54. Gao X, Xing D, Liu L, Tang Y. H-Ras and PI3K are required for the formation of circular dorsal ruffles induced by low-power laser irradiation. J Cell Physiol. 2009;219:535-43 pubmed publisher
    ..J. Cell. Physiol. 219: 535-543, 2009. (c) 2009 Wiley-Liss, Inc...
  55. Koehne J, Stevens R, Zink T, Deng Z, Chen H, Weng I, et al. Using carbon nanotube probes for high-resolution three-dimensional imaging of cells. Ultramicroscopy. 2011;111:1155-62 pubmed publisher
    ..The high aspect ratio of CNT probes provides a very effective remedy to the cliff-like artifacts as well as tip convolution of conventional probes, which shall enhance the validity and application of AFM in cellular biology research...
  56. Manning A, Kuehn M. Contribution of bacterial outer membrane vesicles to innate bacterial defense. BMC Microbiol. 2011;11:258 pubmed publisher
    ..Antimicrobial peptides as well as bacteriophage were used to examine the effectiveness of OMV protection...
  57. Herault O, Binet C, Rico A, Degenne M, Bernard M, Chassaigne M, et al. Evaluation of performance of white blood cell reduction filters: an original flow cytometric method for detection and quantification of cell-derived membrane fragments. Cytometry. 2001;45:277-84 pubmed
    ..We developed an original flow cytometric method that allows the detection and quantification of membrane fragments in filtered products and the evaluation of the quantity of destroyed cells...
  58. Rohde M, Püls J, Buhrdorf R, Fischer W, Haas R. A novel sheathed surface organelle of the Helicobacter pylori cag type IV secretion system. Mol Microbiol. 2003;49:219-34 pubmed
    ..These observations demonstrate for the first time by microscopic techniques a complex T4SS-associated, sheathed surface organelle reminiscent to the needle structures of bacterial type III secretion systems...
  59. Siegel R, Muppidi J, Sarker M, Lobito A, Jen M, Martin D, et al. SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane. J Cell Biol. 2004;167:735-44 pubmed
    ..Analysis of cells expressing Fas mutations from patients with the autoimmune lymphoproliferative syndrome (ALPS) reveals that formation of SPOTS can be disrupted by distinct mechanisms in ALPS...
  60. Webb B, Eves R, Mak A. Cortactin regulates podosome formation: roles of the protein interaction domains. Exp Cell Res. 2006;312:760-9 pubmed
    ..These results suggest that the SH3 domain and the actin-binding repeat region are involved, respectively, in the early and late stages of podosome formation process...
  61. Rehm M, Huber H, Hellwig C, Anguissola S, Dussmann H, Prehn J. Dynamics of outer mitochondrial membrane permeabilization during apoptosis. Cell Death Differ. 2009;16:613-23 pubmed publisher
    ..Taken together, our study yielded the first comprehensive analysis of clonal cell-to-cell variability in apoptosis execution and allowed to visualize and explain the dynamics of MOMP in cells undergoing apoptosis...
  62. Tao Cheng J, Dosemeci A, Gallant P, Miller S, Galbraith J, Winters C, et al. Rapid turnover of spinules at synaptic terminals. Neuroscience. 2009;160:42-50 pubmed publisher
    ..The rapid turnover of synaptic spinules may represent an aspect of membrane retrieval during synaptic activity. ..
  63. Destaing O, Planus E, Bouvard D, Oddou C, Badowski C, Bossy V, et al. ?1A integrin is a master regulator of invadosome organization and function. Mol Biol Cell. 2010;21:4108-19 pubmed publisher
  64. Hurley J, Boura E, Carlson L, Różycki B. Membrane budding. Cell. 2010;143:875-87 pubmed publisher
    ..This Review discusses progress toward understanding the structural and energetic bases of these different membrane-budding paradigms. ..
  65. Wakita Y, Kakimoto T, Katoh H, Negishi M. The F-BAR protein Rapostlin regulates dendritic spine formation in hippocampal neurons. J Biol Chem. 2011;286:32672-83 pubmed publisher
    ..We conclude that the F-BAR protein Rapostlin, whose activity is regulated by Rnd2, plays a key role in spine formation through the regulation of membrane dynamics...
  66. Buys A, Van Rooy M, Soma P, van Papendorp D, Lipinski B, Pretorius E. Changes in red blood cell membrane structure in type 2 diabetes: a scanning electron and atomic force microscopy study. Cardiovasc Diabetol. 2013;12:25 pubmed publisher
    ..Effectiveness of treatment regimes on the integrity, cell shape and roughness of RBCs may be tracked, as this cell's health status is crucial to the overall wellness of the diabetic patient...
  67. Angelini M, Akhlaghpour M, Neuman B, Buchmeier M. Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles. MBio. 2013;4: pubmed publisher
    ..This activity appears to require the full-length form of nsp3 for action, as double-membrane vesicles were not seen in cells coexpressing the C-terminal truncation nsp3 with nsp4 and nsp6...
  68. Kriebel M, Keller B, Silver R, Fox G, Pappas G. Porocytosis: a new approach to synaptic function. Brain Res Brain Res Rev. 2001;38:20-32 pubmed
    ..Changes in the number of docked vesicle-secretory pore complexes composing the array can explain facilitation, depletion, graded excitation-secretion and long term plasticity...
  69. Cunderlikova B, Sikurova L, Moan J. pH, serum proteins and ionic strength influence the uptake of merocyanine 540 by WiDr cells and its interaction with membrane structures. Bioelectrochemistry. 2003;59:1-10 pubmed
    ..The results might provide an explanation of the pH dependency of the cellular uptake of MC 540 observed in this study...
  70. Janssens B, Chavrier P. Mediterranean views on epithelial polarity. Nat Cell Biol. 2004;6:493-6 pubmed
  71. Johansson M, Lye M, Barthel S, Duffy A, Annis D, Mosher D. Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes. Am J Respir Cell Mol Biol. 2004;31:413-22 pubmed
    ..Podosome-mediated VCAM-1 clearance may be a mechanism to regulate eosinophil arrest and extravasation in allergic conditions such as asthma...
  72. Resh M. Membrane targeting of lipid modified signal transduction proteins. Subcell Biochem. 2004;37:217-32 pubmed
    ..Heterogeneity in the types of membrane subdomains, as well as in the types of lipophilic groups that are attached to proteins, provide an additional level of complexity in the regulation of signaling by membrane bound proteins...
  73. Sharma N, Low S, Misra S, Pallavi B, Weimbs T. Apical targeting of syntaxin 3 is essential for epithelial cell polarity. J Cell Biol. 2006;173:937-48 pubmed
    ..These results indicate that SNARE proteins contribute to the overall specificity of membrane trafficking in vivo, and that the polarity of syntaxin 3 is essential for epithelial cell polarization...
  74. Treanor B, Lanigan P, Kumar S, Dunsby C, Munro I, Auksorius E, et al. Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses. J Cell Biol. 2006;174:153-61 pubmed
    ..Spatial confinement of receptor phosphorylation within the immune synapse may be critical to how activating and inhibitory signals are integrated in NK cells...
  75. Jena B. Intracellular organelle dynamics at nm resolution. Methods Cell Biol. 2008;90:19-37 pubmed publisher
    ..Atomic force microscopy and photon correlation spectroscopy have been major players in these studies...
  76. Li Y, Lipowsky R, Dimova R. Membrane nanotubes induced by aqueous phase separation and stabilized by spontaneous curvature. Proc Natl Acad Sci U S A. 2011;108:4731-6 pubmed publisher
    ..Membrane tubes, which can form and be retracted easily, should be relevant for lipid storage in cells...
  77. Sikorska E, Iłowska E, Wyrzykowski D, Kwiatkowska A. Membrane structure and interactions of peptide hormones with model lipid bilayers. Biochim Biophys Acta. 2012;1818:2982-93 pubmed publisher
    ..In turn, above T(m), the electrostatic interactions become also relevant for the conformation of the acyclic tail of the AVP-like peptides...
  78. Soberon M, Perez R, Nuñez Valdéz M, Lorence A, Gomez I, Sanchez J, et al. Evidence for intermolecular interaction as a necessary step for pore-formation activity and toxicity of Bacillus thuringiensis Cry1Ab toxin. FEMS Microbiol Lett. 2000;191:221-5 pubmed
    ..sexta larvae when mixed, showing that monomers affected in different steps of their mode of action can form functional hetero-oligomers...
  79. Salehnia M. Different pattern of pinopodes expression in stimulated mouse endometrium. Exp Anim. 2005;54:349-52 pubmed
  80. Kenis H, van Genderen H, Deckers N, Lux P, Hofstra L, Narula J, et al. Annexin A5 inhibits engulfment through internalization of PS-expressing cell membrane patches. Exp Cell Res. 2006;312:719-26 pubmed
    ..Interestingly, cells with internalized annexin A5 still express PS at their surface. We conclude that other ligands within the PS-expressing membrane patch act together with PS as an "eat me" signal...
  81. Bargmann B, Munnik T. The role of phospholipase D in plant stress responses. Curr Opin Plant Biol. 2006;9:515-22 pubmed
    ..PLD and its product, phosphatidic acid, exert their effects by functioning in signal transduction cascades and by influencing the biophysical state of lipid membranes...
  82. Yamashita S, Oku M, Sakai Y. Functions of PI4P and sterol glucoside are necessary for the synthesis of a nascent membrane structure during pexophagy. Autophagy. 2007;3:35-7 pubmed
    ..In this addendum, we review these findings, and speculate on the mechanistic and physiological implications of the functions of these lipids during the autophagic process...
  83. Carneiro S, Fernandes W, Sant Anna S, Yamanouye N. Microvesicles in the venom of Crotalus durissus terrificus (Serpentes, Viperidae). Toxicon. 2007;49:106-10 pubmed
    ..A fine fuzzy coat surrounded each microvesicle. The function of these venom vesicles is still unknown, but they may contribute to inactivation of stored venom components, or their activation after the venom is released...
  84. Håberg K, Lundmark R, Carlsson S. SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking. J Cell Sci. 2008;121:1495-505 pubmed publisher
    ..The results indicate that SNX9-family members make up discrete membrane-scission units together with dynamin, and suggest that SNX18 mediates budding of carriers for AP-1-positive endosomal trafficking...
  85. Xu Friedman M, Harris K, Regehr W. Three-dimensional comparison of ultrastructural characteristics at depressing and facilitating synapses onto cerebellar Purkinje cells. J Neurosci. 2001;21:6666-72 pubmed
    ..Similarities in the number of docked vesicles for PF and CF synapses indicate that differences in probability of release are unrelated to the number of anatomically docked vesicles at these synapses...
  86. Cohen R. The role of membranes and membrane trafficking in RNA localization. Biol Cell. 2005;97:5-18 pubmed
    ..9, m60-m64)...
  87. Spitzer N. A Rosetta stone for analysis of human membrane protein function. Proc Natl Acad Sci U S A. 2008;105:10641-2 pubmed publisher
  88. Pan Y, Chen C, Chen H. FAK is required for the assembly of podosome rosettes. J Cell Biol. 2011;195:113-29 pubmed publisher
    ..Collectively, our results strongly suggest a link between FAK, podosome rosettes, and tumor invasion and unveil a negative role for Rho signaling and vimentin filaments in podosome rosette assembly...
  89. McLaughlin L, Haft R, Forest K. Structural insights into the Type II secretion nanomachine. Curr Opin Struct Biol. 2012;22:208-16 pubmed publisher
    ..Combining structures and protein interactions, we synthesize a 3D view of the complete complex consistent with a stepwise pathway in which secretin oligomerization defines sites of nanomachine biogenesis...
  90. Ben Dov N, Korenstein R. Enhancement of cell membrane invaginations, vesiculation and uptake of macromolecules by protonation of the cell surface. PLoS ONE. 2012;7:e35204 pubmed publisher
    ..We suggest that protonation of the cell's surface induces local charge asymmetries across the cell membrane bilayer, inducing inward curvature of the cell membrane and consequent vesiculation and uptake...
  91. Al Abdul Wahid M, DeMill C, Serwin M, Prosser R, Stewart B. Effect of juxtamembrane tryptophans on the immersion depth of Synaptobrevin, an integral vesicle membrane protein. Biochim Biophys Acta. 2012;1818:2994-9 pubmed publisher
    ..These data therefore indicate that juxtamembrane tryptophan residues are important determinants of the position of Synaptobrevin in the membrane...
  92. Laukaitis C, Webb D, Donais K, Horwitz A. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. J Cell Biol. 2001;153:1427-40 pubmed
    ..After adhesions broke down in the rear, alpha 5-GFP was found in fibrous structures behind the cell, whereas alpha-actinin--GFP and paxillin-GFP moved up the lateral edge of retracting cells as organized structures and then dissipated...
  93. Wang C, Grishanin R, Earles C, Chang P, Martin T, Chapman E, et al. Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles. Science. 2001;294:1111-5 pubmed
    ..Both synaptotagmin isoforms reduced norepinephrine flux through open fusion pores. Thus, synaptotagmin interacts with fusion pores, possibly by associating with a core complex of membrane proteins and/or lipid...
  94. Patel P, Harrison R. Membrane ruffles capture C3bi-opsonized particles in activated macrophages. Mol Biol Cell. 2008;19:4628-39 pubmed publisher
    ..Importantly, this work also demonstrates a strong functional link between integrin activation, macropinocytosis and phagocytosis in macrophages...
  95. Bloodgood R. The future of ciliary and flagellar membrane research. Mol Biol Cell. 2012;23:2407-11 pubmed publisher