membrane fluidity


Summary: The motion of phospholipid molecules within the lipid bilayer, dependent on the classes of phospholipids present, their fatty acid composition and degree of unsaturation of the acyl chains, the cholesterol concentration, and temperature.

Top Publications

  1. Wrobel D, Kłys A, Ionov M, Vitovic P, Waczulikowa I, Hianik T, et al. Cationic carbosilane dendrimers-lipid membrane interactions. Chem Phys Lipids. 2012;165:401-7 pubmed publisher
    ..was observed for both fluorescent probes when dendrimers were added to lipids that means the decreased membrane fluidity. Both the hydrophobic and hydrophilic parts of liposome bilayers became more rigid...
  2. Saxena S, Srivastava P, Khanna V. Antioxidant supplementation improves platelet membrane fluidity in idiopathic retinal periphlebitis (Eales' disease). J Ocul Pharmacol Ther. 2010;26:623-6 pubmed publisher prospective study was undertaken to study the effect of antioxidant supplementation over membrane fluidity in platelets in idiopathic retinal periphlebitis (Eales' disease) for the first time...
  3. Chen L, Meng Q, Jing X, Xu P, Luo D. A role for protein kinase C in the regulation of membrane fluidity and Ca²(+) flux at the endoplasmic reticulum and plasma membranes of HEK293 and Jurkat cells. Cell Signal. 2011;23:497-505 pubmed publisher
    ..Measurements of membrane fluidity showed that, like the cell membrane stabilizers bovine serum albumin (BSA) and ursodeoxycholate (UDCA), PMA ..
  4. Mishra N, Liu G, Yeaman M, Nast C, Proctor R, McKinnell J, et al. Carotenoid-related alteration of cell membrane fluidity impacts Staphylococcus aureus susceptibility to host defense peptides. Antimicrob Agents Chemother. 2011;55:526-31 pubmed publisher
    ..aureus to subvert nonoxidative host defenses mediated by cationic peptides, potentially by increasing target membrane rigidity. ..
  5. Ajdžanović V, Spasojevic I, Sošić Jurjević B, Filipović B, Trifunović S, Sekulić M, et al. The negative effect of soy extract on erythrocyte membrane fluidity: an electron paramagnetic resonance study. J Membr Biol. 2011;239:131-5 pubmed publisher
    A decrease of erythrocyte membrane fluidity can contribute to the pathophysiology of hypertension...
  6. Yang X, Sheng W, Sun G, Lee J. Effects of fatty acid unsaturation numbers on membrane fluidity and ?-secretase-dependent amyloid precursor protein processing. Neurochem Int. 2011;58:321-9 pubmed publisher
    ..pathways of Alzheimer's disease (AD), we systematically investigated the effects of fatty acids on cell membrane fluidity and ?-secretase-cleaved soluble amyloid precursor protein (sAPP(?)) secretion in relation to unsaturation ..
  7. Maccarrone M, Bernardi G, Agrò A, Centonze D. Cannabinoid receptor signalling in neurodegenerative diseases: a potential role for membrane fluidity disturbance. Br J Pharmacol. 2011;163:1379-90 pubmed publisher
    ..Here, the hypothesis that changes in membrane fluidity alter function of the endocannabinoid system, as well as progression of particular neurodegenerative ..
  8. Capozzi V, Weidmann S, Fiocco D, Rieu A, Hols P, Guzzo J, et al. Inactivation of a small heat shock protein affects cell morphology and membrane fluidity in Lactobacillus plantarum WCFS1. Res Microbiol. 2011;162:419-25 pubmed publisher
    ..plantarum cells. Furthermore, inactivation of the hsp 18.55 gene affected membrane fluidity and physicochemical surface properties of L. plantarum WCFS1.
  9. Zhang X, Hurng J, Rateri D, Daugherty A, Schmid Schonbein G, Shin H. Membrane cholesterol modulates the fluid shear stress response of polymorphonuclear leukocytes via its effects on membrane fluidity. Am J Physiol Cell Physiol. 2011;301:C451-60 pubmed publisher
    ..96; P < 0.0001) with cholesterol-related membrane fluidity. Moreover, in low-density lipoprotein receptor-deficient (LDLr(-/-)) mice fed a high-fat diet (a ..

More Information


  1. Schaeffer E, Skaf H, Novaes B, da Silva E, Martins B, Joaquim H, et al. Inhibition of phospholipase A? in rat brain modifies different membrane fluidity parameters in opposite ways. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:1612-7 pubmed publisher
    ..of in vivo infusion of the dual cPLA(2) and iPLA(2) inhibitor MAFP into rat brain on PLA(2) activity and membrane fluidity parameters in the postmortem frontal cortex and dorsal hippocampus...
  2. Huffer S, Clark M, Ning J, Blanch H, Clark D. Role of alcohols in growth, lipid composition, and membrane fluidity of yeasts, bacteria, and archaea. Appl Environ Microbiol. 2011;77:6400-8 pubmed publisher
    Increased membrane fluidity, which causes cofactor leakage and loss of membrane potential, has long been documented as a cause for decreased cell growth during exposure to ethanol, butanol, and other alcohols...
  3. Turk M, Plemenitas A, Gunde Cimerman N. Extremophilic yeasts: plasma-membrane fluidity as determinant of stress tolerance. Fungal Biol. 2011;115:950-8 pubmed publisher the level of their plasma membranes, in order to elucidate the connections between their plasma-membrane fluidity (measured by electron paramagnetic resonance spectroscopy - EPR), growth temperature range, stress tolerance,..
  4. Rifler J, Lorcerie F, Durand P, Delmas D, Ragot K, Limagne E, et al. A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients. Mol Nutr Food Res. 2012;56:345-51 pubmed publisher
    ..of low wine consumption on blood parameters (decrease in total cholesterol and LDL; increase in erythrocyte membrane fluidity and antioxidant status)...
  5. Krtková J, Havelkova L, Krepelova A, Fiser R, Vosolsobě S, Novotná Z, et al. Loss of membrane fluidity and endocytosis inhibition are involved in rapid aluminum-induced root growth cessation in Arabidopsis thaliana. Plant Physiol Biochem. 2012;60:88-97 pubmed publisher
    ..from Arabidopsis plants and labeled with the fluorescent probe laurdan showed that Al induced a reduction in membrane fluidity. Application of the membrane fluidizer, benzyl alcohol, restored partially membrane fluidity and also ..
  6. Maurya S, Chaturvedi D, Mahalakshmi R. Modulating lipid dynamics and membrane fluidity to drive rapid folding of a transmembrane barrel. Sci Rep. 2013;3:1989 pubmed publisher
    ..We establish that OmpX thus folded is highly thermostable even in detergent micelles, and retains structural characteristics comparable to the protein in bilayers. ..
  7. Mendanha S, Moura S, Anjos J, Valadares M, Alonso A. Toxicity of terpenes on fibroblast cells compared to their hemolytic potential and increase in erythrocyte membrane fluidity. Toxicol In Vitro. 2013;27:323-9 pubmed publisher
    ..stearic acid (5-DSA) was used to monitor the effect of sesquiterpene nerolidol and various monoterpenes on membrane fluidity in erythrocyte and fibroblast cells...
  8. Mercier R, Domínguez Cuevas P, Errington J. Crucial role for membrane fluidity in proliferation of primitive cells. Cell Rep. 2012;1:417-23 pubmed publisher
    ..The failure in scission is associated with a reduction in membrane fluidity. The results identify a step in L-form proliferation and demonstrate that purely biophysical processes may ..
  9. Haratake M, Takahira E, Yoshida S, Osei Asante S, Fuchigami T, Nakayama M. Improved membrane fluidity of ionic polysaccharide bead-supported phospholipid bilayer membrane systems. Colloids Surf B Biointerfaces. 2013;107:90-6 pubmed publisher
    ..Furthermore, such fluid phospholipid bilayer membranes formed on the polysaccharide-based cationic polymer bead were maintained for 10 days, even though the complex sample was stood in plain buffer (pH 8.5) at ambient temperature. ..
  10. Miana Mena F, Piedrafita E, González Mingot C, Larrodé P, Muñoz M, Martínez Ballarín E, et al. Levels of membrane fluidity in the spinal cord and the brain in an animal model of amyotrophic lateral sclerosis. J Bioenerg Biomembr. 2011;43:181-6 pubmed publisher
    ..Using fluorescence spectroscopy, we monitored membrane fluidity in the spinal cord and the brain in a widely used animal model of ALS, the SOD(G93A) mouse, which develops ..
  11. Sonmez M, Ince H, Yalcin O, Ajdžanović V, Spasojevic I, Meiselman H, et al. The effect of alcohols on red blood cell mechanical properties and membrane fluidity depends on their molecular size. PLoS ONE. 2013;8:e76579 pubmed publisher
    The role of membrane fluidity in determining red blood cell (RBC) deformability has been suggested by a number of studies...
  12. Csoboz B, Balogh G, Kusz E, Gombos I, Peter M, Crul T, et al. Membrane fluidity matters: hyperthermia from the aspects of lipids and membranes. Int J Hyperthermia. 2013;29:491-9 pubmed publisher
    ..Due to lipid imbalances and 'membrane defects' most of the tumour cells possess elevated membrane fluidity. However, further increasing membrane fluidity to sensitise to chemo- or radiotherapy could have some other ..
  13. Dubas E, Janowiak F, Krzewska M, Hura T, Zur I. Endogenous ABA concentration and cytoplasmic membrane fluidity in microspores of oilseed rape (Brassica napus L.) genotypes differing in responsiveness to androgenesis induction. Plant Cell Rep. 2013;32:1465-75 pubmed publisher
    A better understanding of androgenesis with a focus on the changes in plasma membrane fluidity and endogenous ABA content affecting embryogenesis induction in microspore suspension of B. napus...
  14. Vilas Boas V, Silva R, Nunes C, Reis S, Ferreira L, Vieira C, et al. Mechanisms of P-gp inhibition and effects on membrane fluidity of a new rifampicin derivative, 1,8-dibenzoyl-rifampicin. Toxicol Lett. 2013;220:259-66 pubmed publisher
    ..b>Membrane fluidity changes were tracked by steady-state anisotropy measurements...
  15. Alvarez Berríos M, Castillo A, Méndez J, Soto O, Rinaldi C, Torres Lugo M. Hyperthermic potentiation of cisplatin by magnetic nanoparticle heaters is correlated with an increase in cell membrane fluidity. Int J Nanomedicine. 2013;8:1003-13 pubmed publisher
    ..Changes in membrane fluidity were tested through fluorescence anisotropy measurements using trimethylamine-diphenylhexatriene...
  16. Espinosa G, López Montero I, Monroy F, Langevin D. Shear rheology of lipid monolayers and insights on membrane fluidity. Proc Natl Acad Sci U S A. 2011;108:6008-13 pubmed publisher
    The concept of membrane fluidity usually refers to a high molecular mobility inside the lipid bilayer which enables lateral diffusion of embedded proteins...
  17. Lockshon D, Olsen C, Brett C, Chertov A, Merz A, Lorenz D, et al. Rho signaling participates in membrane fluidity homeostasis. PLoS ONE. 2012;7:e45049 pubmed publisher
    ..The differential influence of palmitoleate and oleate on growth of key mutants correlated with changes in membrane fluidity measured by fluorescence anisotropy of TMA-DPH, a plasma membrane-bound dye...
  18. Kingston A, Subramanian C, Rock C, Helmann J. A ?W-dependent stress response in Bacillus subtilis that reduces membrane fluidity. Mol Microbiol. 2011;81:69-79 pubmed publisher
    ..The net effect is to reduce membrane fluidity. The inactivation of the ?(W)-dependent promoter within fabHa increased sensitivity to detergents and to ..
  19. Grebowski J, Krokosz A, Puchala M. Membrane fluidity and activity of membrane ATPases in human erythrocytes under the influence of polyhydroxylated fullerene. Biochim Biophys Acta. 2013;1828:241-8 pubmed publisher
    ..Moreover, fullerenol influences membrane ATPases so that it may modulate ion transport across membranes...
  20. de la Haba C, Palacio J, Martinez P, Morros A. Effect of oxidative stress on plasma membrane fluidity of THP-1 induced macrophages. Biochim Biophys Acta. 2013;1828:357-64 pubmed publisher
    ..This process modifies membrane properties such as membrane fluidity, a very important physical feature known to modulate membrane protein localization and function...
  21. Mironov K, Sidorov R, Trofimova M, Bedbenov V, Tsydendambaev V, Allakhverdiev S, et al. Light-dependent cold-induced fatty acid unsaturation, changes in membrane fluidity, and alterations in gene expression in Synechocystis. Biochim Biophys Acta. 2012;1817:1352-9 pubmed publisher
    Cold stress causes unsaturation of the membrane lipids. This leads to adjustment of the membrane fluidity, which is necessary for cold acclimation of cells...
  22. Illien F, Piao H, Coué M, Di Marco C, Ayala Sanmartin J. Lipid organization regulates annexin A2 Ca(2+)-sensitivity for membrane bridging and its modulator effects on membrane fluidity. Biochim Biophys Acta. 2012;1818:2892-900 pubmed publisher
    ..the influence of lipid composition on the Ca(2+)-dependency of AnxA2-mediated membrane bridging and on membrane fluidity. Membrane models of ten different lipid compositions and detergent-resistant membranes from two cellular ..
  23. Gurtovenko A, Anwar J. Interaction of ethanol with biological membranes: the formation of non-bilayer structures within the membrane interior and their significance. J Phys Chem B. 2009;113:1983-92 pubmed publisher
  24. Mykytczuk N, Trevors J, Ferroni G, Leduc L. Cytoplasmic membrane fluidity and fatty acid composition of Acidithiobacillus ferrooxidans in response to pH stress. Extremophiles. 2010;14:427-41 pubmed publisher
    ..Growth rate, membrane fluidity and phase, determined from the fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene, and fatty acid ..
  25. Kadirvel G, Kumar S, Kumaresan A, Kathiravan P. Capacitation status of fresh and frozen-thawed buffalo spermatozoa in relation to cholesterol level, membrane fluidity and intracellular calcium. Anim Reprod Sci. 2009;116:244-53 pubmed publisher
    ..status of fresh and frozen-thawed buffalo spermatozoa and its relationship with sperm cholesterol level, membrane fluidity and intracellular calcium. Semen from seven buffalo bulls (eight ejaculates each) was divided into two parts...
  26. Banerjee S, Ghosh J, Sen S, Guha R, Dhar R, Ghosh M, et al. Designing therapies against experimental visceral leishmaniasis by modulating the membrane fluidity of antigen-presenting cells. Infect Immun. 2009;77:2330-42 pubmed publisher
    The membrane fluidity of antigen-presenting cells (APCs) has a significant bearing on T-cell-stimulating ability and is dependent on the cholesterol content of the membrane...
  27. Ariola F, Li Z, Cornejo C, Bittman R, Heikal A. Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative. Biophys J. 2009;96:2696-708 pubmed publisher
    ..Here, we use a new Bodipy-labeled cholesterol (Bdp-Chol) derivative to investigate membrane fluidity, lipid order, and partitioning in various lipid phases in giant unilamellar vesicles (GUVs) as a model ..
  28. Najle S, Inda M, de Mendoza D, Cybulski L. Oligomerization of Bacillus subtilis DesR is required for fine tuning regulation of membrane fluidity. Biochim Biophys Acta. 2009;1790:1238-43 pubmed publisher
    ..In addition, we present evidence showing that RB is physiologically relevant to control the activation of the des gene when the levels of DesR-P reach a critical threshold...
  29. Sergent O, Ekroos K, Lefeuvre Orfila L, Rissel M, Forsberg G, Oscarsson J, et al. Ximelagatran increases membrane fluidity and changes membrane lipid composition in primary human hepatocytes. Toxicol In Vitro. 2009;23:1305-10 pubmed publisher
    ..The aim of this study was to investigate whether ximelagatran has an effect on the plasma membrane fluidity and the membrane lipid composition which may be important for the cell integrity...
  30. Yang X, Sheng W, He Y, Cui J, Haidekker M, Sun G, et al. Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity. J Lipid Res. 2010;51:957-66 pubmed publisher
    ..and decreased levels of Abeta(1-42) in SH-SY5Y cells, and these changes were accompanied by increased membrane fluidity. We further tested whether sPLA(2)-III-enhanced sAPP(alpha) release is due in part to the production of its ..
  31. Beranová J, Jemioła Rzemińska M, Elhottová D, Strzałka K, Konopasek I. Metabolic control of the membrane fluidity in Bacillus subtilis during cold adaptation. Biochim Biophys Acta. 2008;1778:445-53 pubmed
    b>Membrane fluidity adaptation to the low growth temperature in Bacillus subtilis involves two distinct mechanisms: (1) long-term adaptation accomplished by increasing the ratio of anteiso- to iso-branched fatty acids and (2) rapid ..
  32. Coccia R, Spadaccio C, Foppoli C, Perluigi M, Covino E, Lusini M, et al. The effect of simvastatin on erythrocyte membrane fluidity during oxidative stress induced by cardiopulmonary bypass: a randomized controlled study. Clin Ther. 2007;29:1706-17 pubmed
    ..The goals of this study were to evaluate changes in erythrocyte membrane fluidity and lipid peroxidation during CPB and to examine the effect of simvastatin treatment on these parameters...
  33. Gossai D, Lau Cam C. The effects of taurine, hypotaurine, and taurine homologs on erythrocyte morphology, membrane fluidity and cytoskeletal spectrin alterations due to diabetes, alcoholism and diabetes-alcoholism in the rat. Adv Exp Med Biol. 2009;643:369-79 pubmed publisher
    ..HMTAU) were tested for their counteracting effects against alterations in erythrocyte (RBC) morphology, membrane fluidity and cytoskeletal spectrin distribution due to diabetes, alcoholism and diabetes-alcoholism in male Goto-..
  34. Cao Hoang L, Dumont F, Marechal P, Le Thanh M, Gervais P. Rates of chilling to 0 degrees C: implications for the survival of microorganisms and relationship with membrane fluidity modifications. Appl Microbiol Biotechnol. 2008;77:1379-87 pubmed
    ..2 degrees C min(-1)) and rapid chilling (2,000 degrees C min(-1)) were investigated on the survival and membrane fluidity of Escherichia coli, of Bacillus subtilis, and of Saccharomyces cerevisiae...
  35. Gunawan R, Auguste D. The role of antibody synergy and membrane fluidity in the vascular targeting of immunoliposomes. Biomaterials. 2010;31:900-7 pubmed publisher
    ..SMCs, which do not express ELAM, show a dependence on aICAM surface density. These results suggest that antibody mobility and molar ratio play a key role in increasing receptor-mediated cell targeting. ..
  36. Chadha V, Dhawan D. Membrane fluidity and surface changes during initiation of 1,2 dimethylhydrazine-induced colon carcinogenesis: protection by zinc. Oncol Res. 2009;18:17-23 pubmed
    The present study evaluated the modulatory effects of zinc on colonic membrane fluidity and surface abnormalities following 1,2 dimethylhydrazine (DMH)-induced colon carcinogenesis...
  37. Hon G, Hassan M, van Rensburg S, Abel S, van Jaarsveld P, Erasmus R, et al. Red blood cell membrane fluidity in the etiology of multiple sclerosis. J Membr Biol. 2009;232:25-34 pubmed publisher
    ..We investigated membrane fluidity using the phospholipid, fatty acid and cholesterol content of red blood cells (RBCs) from multiple sclerosis ..
  38. Ding L, Chi E, Schanze K, Lopez G, Whitten D. Insight into the mechanism of antimicrobial conjugated polyelectrolytes: lipid headgroup charge and membrane fluidity effects. Langmuir. 2010;26:5544-50 pubmed publisher
    ..We observe that increasing membrane fluidity enhances both the conformational changes of polymer 1 upon associating with lipid membranes and the extent ..
  39. Palma Guerrero J, Lopez Jimenez J, Pérez Berná A, Huang I, Jansson H, Salinas J, et al. Membrane fluidity determines sensitivity of filamentous fungi to chitosan. Mol Microbiol. 2010;75:1021-32 pubmed publisher
    ..acids than chitosan-resistant fungi, suggesting that their permeabilization by chitosan may be dependent on membrane fluidity. A fatty acid desaturase mutant of Neurospora crassa with reduced plasma membrane fluidity exhibited ..
  40. Shlomovitz R, Gov N. Physical model of contractile ring initiation in dividing cells. Biophys J. 2008;94:1155-68 pubmed
    ..We find a quantization of this process at distinct length-scales, which we compare to available data for different types of eukaryote cells. ..
  41. Tsuda K. Electron paramagnetic resonance investigation on modulatory effect of benidipine on membrane fluidity of erythrocytes in essential hypertension. Heart Vessels. 2008;23:134-9 pubmed publisher
    ..We measured the membrane fluidity of erythrocytes by using an electron paramagnetic resonance (EPR) and spin-labeling method...
  42. Deng Y, Wang Y, Holtz B, Li J, Traaseth N, Veglia G, et al. Fluidic and air-stable supported lipid bilayer and cell-mimicking microarrays. J Am Chem Soc. 2008;130:6267-71 pubmed publisher
    ..These demonstrations establish the viability of the fluidic and air-stable SLB platform for generating content microarrays in high throughput studies, e.g., the screening of drugs and nanomedicine targeting cell surface receptors. ..
  43. Sousa C, Nunes C, Lucio M, Ferreira H, Lima J, Tavares J, et al. Effect of nonsteroidal anti-inflammatory drugs on the cellular membrane fluidity. J Pharm Sci. 2008;97:3195-206 pubmed
    ..Fluorescence anisotropy measurements were also made to investigate the effects on membrane fluidity resulting from the interaction between the drugs and membrane systems...
  44. Mishra M, Ghosh D, Duseja R, Basu A. Antioxidant potential of Minocycline in Japanese Encephalitis Virus infection in murine neuroblastoma cells: correlation with membrane fluidity and cell death. Neurochem Int. 2009;54:464-70 pubmed publisher
    ..Our findings suggest that Minocycline reduces the neuronal damage seen in JEV infection in neuronal cell culture models at least in part through inhibition of oxidative stress. ..
  45. Yeruva L, Elegbede J, Carper S. Methyl jasmonate decreases membrane fluidity and induces apoptosis through tumor necrosis factor receptor 1 in breast cancer cells. Anticancer Drugs. 2008;19:766-76 pubmed publisher
    ..Cellular signaling studies with MJ showed decreased membrane fluidity and activation of extrinsic and intrinsic apoptotic pathways...
  46. Königshofer H, Tromballa H, Löppert H. Early events in signalling high-temperature stress in tobacco BY2 cells involve alterations in membrane fluidity and enhanced hydrogen peroxide production. Plant Cell Environ. 2008;31:1771-80 pubmed publisher
    Alterations in membrane fluidity are among the early events in plants that detect changes in ambient temperature. However, signal transduction downstream of the membrane-associated processes is still not well understood...
  47. Kamboj S, Chopra K, Sandhir R. Hyperglycemia-induced alterations in synaptosomal membrane fluidity and activity of membrane bound enzymes: beneficial effect of N-acetylcysteine supplementation. Neuroscience. 2009;162:349-58 pubmed publisher
    ..4-1.5 g/kg body weight) for eight weeks and lipid composition along with membrane fluidity were determined...
  48. Zhang G, Bao P, Zhang Y, Deng A, Chen N, Wen T. Enhancing electro-transformation competency of recalcitrant Bacillus amyloliquefaciens by combining cell-wall weakening and cell-membrane fluidity disturbing. Anal Biochem. 2011;409:130-7 pubmed publisher
    ..hypertonic medium, cell walls were weakened by adding glycine (Gly) and DL-threonine (DL-Thr), and the cell-membrane fluidity was elevated by supplementing Tween 80...
  49. Goi G, Massaccesi L, Baquero Herrera C, Musetti C, Ciurlino D, Cusi D, et al. Oxidative stress in elderly chronic renal failure patients: effects of renal replacement therapies on cell membrane fluidity. J Nephrol. 2009;22:630-6 pubmed
    ..and formation of reactive oxygen species (ROS), which are a major factor involved in alterations of plasma membrane fluidity and endothelial activation, but their role on plasma membrane fluidity in vivo is still unclear...
  50. Man D, Olchawa R, Kubica K. Membrane fluidity and the surface properties of the lipid bilayer: ESR experiment and computer simulation. J Liposome Res. 2010;20:211-8 pubmed publisher
    ..The limited mobility of lipid polar heads (k < 0.2) prevents the appearance of such areas facilitating the penetration of the lipid membrane by alien particles in the gel phase. ..
  51. Maturu P, Vaddi D, Pannuru P, Nallanchakravarthula V. Alterations in erythrocyte membrane fluidity and Na+/K+ -ATPase activity in chronic alcoholics. Mol Cell Biochem. 2010;339:35-42 pubmed publisher
    ..Alcohol-induced overproduction of nitric oxide reacts with superoxide radicals to produce peroxynitrite, which appears to be responsible for changes in erythrocyte membrane lipids and the activity of Na(+)/K(+)-ATPase. ..
  52. Ajdžanović V, Spasojevic I, Filipović B, Sošić Jurjević B, Sekulić M, Milosevic V. Effects of genistein and daidzein on erythrocyte membrane fluidity: an electron paramagnetic resonance study. Can J Physiol Pharmacol. 2010;88:497-500 pubmed publisher
    The maintenance of erythrocyte membrane fluidity at the physiological level is an important factor affecting the ability of erythrocytes to pass through blood vessels of small luminal diameter...
  53. Becker S, Ardisson V, Lepareur N, Sergent O, Bayat S, Noiret N, et al. Increased Lipiodol uptake in hepatocellular carcinoma possibly due to increased membrane fluidity by dexamethasone and tamoxifen. Nucl Med Biol. 2010;37:777-84 pubmed publisher
    ..The effect of dexamethasone and tamoxifen on membrane fluidity was studied in vitro by electron paramagnetic resonance applied to rat hepatocarcinoma cell line N1S1...