retinal telangiectasis


Summary: A group of rare, idiopathic, congenital retinal vascular anomalies affecting the retinal capillaries. It is characterized by dilation and tortuosity of retinal vessels and formation of multiple aneurysms, with different degrees of leakage and exudates emanating from the blood vessels.

Top Publications

  1. Song H, Ai H, Zhu Q, Lei C, Wang J, Lei X. Stage 3B Coats disease in a premature and low-birth-weight infant. Chin Med J (Engl). 2012;125:3759-60 pubmed
  2. Ehmann D, Riyaz R, Greve M. Central retinal artery occlusion in a child with Parry-Romberg syndrome. Can J Ophthalmol. 2014;49:e9-10 pubmed publisher
  3. Ong S, Buckley E, McCuen B, Jaffe G, Postel E, Mahmoud T, et al. Comparison of Visual Outcomes in Coats' Disease: A 20-Year Experience. Ophthalmology. 2017;124:1368-1376 pubmed publisher
    ..This is due to a combination of factors, including earlier presentation of disease, fewer eyes being observed without treatment, and eyes, when treated, receiving a higher number of procedures. ..
  4. Gonzalez M, Shechtman D, Haynie J, Semes L. Unveiling idiopathic macular telangiectasia: clinical applications of optical coherence tomography angiography. Eur J Ophthalmol. 2017;27:e129-e133 pubmed publisher
    ..Additionally, these examples emphasize the critical importance of OCTA in the clinical diagnosis and management of IMT2. ..
  5. Runkle A, Kaiser P, Srivastava S, Schachat A, Reese J, Ehlers J. OCT Angiography and Ellipsoid Zone Mapping of Macular Telangiectasia Type 2 From the AVATAR Study. Invest Ophthalmol Vis Sci. 2017;58:3683-3689 pubmed publisher
    ..OCT-A was a useful adjunct for determining disease severity. ..
  6. Fortunato M, Turtoro A, Cennamo G. Optical Coherence Tomography Angiography in Children with Leber-Coats Disease. Ophthalmic Res. 2017;58:185-187 pubmed publisher
    ..OCTA is a non-invasive and non-contact technique, which can be considered of fundamental importance for the diagnosis, clinical management, and follow-up of the disease. ..
  7. Baumann B, Sterling J, Song Y, Song D, Fruttiger M, Gillies M, et al. Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation. Invest Ophthalmol Vis Sci. 2017;58:4223-4234 pubmed publisher
    ..The retinal iron accumulation resulting from blood-retinal barrier dysfunction may contribute to retinal degeneration in this model and in diseases such as MacTel2 and diabetic retinopathy. ..
  8. Guo J, Tang W, Ye X, Wu H, Xu G, Liu W, et al. Predictive multi-imaging biomarkers relevant for visual acuity in idiopathic macular telangiectasis type 1. BMC Ophthalmol. 2018;18:69 pubmed publisher
    ..CMT, SCP density, total area of EZ disruption, and lengths of EZ and ELM disruption within the 1-mm-diameter central region were strongly associated with VA. ..
  9. Li S, Deng G, Liu J, Ma Y, Lu H. The effects of a treatment combination of anti-VEGF injections, laser coagulation and cryotherapy on patients with type 3 Coat's disease. BMC Ophthalmol. 2017;17:76 pubmed publisher
    ..We retrospectively registered our study, The trial registration number (TRN) is ChiCTR-ONC-17011161 and date of registration is April 16, 2017. ..

More Information


  1. Mukherjee D, Lad E, Vann R, Jaffe S, Clemons T, Friedlander M, et al. Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2. Invest Ophthalmol Vis Sci. 2017;58:BIO291-BIO299 pubmed publisher
    ..Our software allows determination of functional and structural changes with increasing disease severity and demonstrates that functional loss on microperimetry may be used as a surrogate marker of EZ loss on SD-OCT in type 2 MacTel. ..